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Galactooligosaccharide

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https://www.readbyqxmd.com/read/27909555/effect-of-dual-type-oligosaccharides-on-constipation-in-loperamide-treated-rats
#1
Sung Hee Han, Ki Bae Hong, Eun Young Kim, So Hyun Ahn, Hyung Joo Suh
BACKGROUND/OBJECTIVES: Constipation is a condition that can result from intestinal deformation. Because humans have an upright posture, the effects of gravity can cause this shape deformation. Oligosaccharides are common prebiotics and their effects on bowel health are well known. However, studies of the physiological functionality of a product that contains both lactulose and galactooligosaccharides are insufficient. We investigated the constipation reduction effect of a dual-type oligosaccharide, Dual-Oligo, in loperamide-treated rats...
December 2016: Nutrition Research and Practice
https://www.readbyqxmd.com/read/27904405/evaluation-of-prebiotic-effects-of-high-purity-galactooligosaccharides-in-vitro-and-in-vivo
#2
Ki Bae Hong, Jae Hwan Kim, Hyuk Kon Kwon, Sung Hee Han, Yooheon Park, Hyung Joo Suh
Galactooligosaccharides (GOS) are an important class of dietary prebiotics that exert beneficial effects on intestinal microbiota and gut barrier function. In this study, high-purity GOS (HP-GOS) were investigated in vitro and in vivo and confirmed as prebiotic ingredients in rat diet. HP-GOS were successfully produced using a two-step process, enzymatic hydrolysis and fermentation by yeast. They were found to serve as a good substrate and carbon source for supporting the growth of probiotic bacteria more effectively than other commercial GOS...
June 2016: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/27856622/in-vitro-fermentation-of-b-gos-impact-on-faecal-bacterial-populations-and-metabolic-activity-in-autistic-and-non-autistic-children
#3
Roberta Grimaldi, Drinalda Cela, Jonathan R Swann, Jelena Vulevic, Glenn R Gibson, George Tzortzis, Adele Costabile
Children with autism spectrum disorders (ASD) often suffer gastrointestinal problems consistent with imbalances in the gut microbial population. Treatment with antibiotics or pro/prebiotics has been postulated to regulate microbiota and improve gut symptoms, but there is a lack of evidence for such approaches, especially for prebiotics. This study assessed the influence of a prebiotic galactooligosaccharide (B-GOS) on gut microbial ecology and metabolic function using faecal samples from autistic and non-autistic children in an in vitro gut model system...
November 16, 2016: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/27775655/effects-of-proton-pump-inhibitor-administration-and-intake-of-a-combination-of-yogurt-and-galactooligosaccharides-on-bone-and-mineral-metabolism-in-rats
#4
Satoshi Takasugi, Miho Shioyama, Masami Kitade, Masashi Nagata, Taketo Yamaji
The aim of this study was to investigate the effects of proton pump inhibitor (PPI), the most potent acid-suppressing drug, administration and intake of a combination of yogurt and galactooligosaccharides (YG) on bone and mineral metabolism in adult rats. Twelve-week-old male Wistar rats were divided into three groups: a control group fed the control diet with vehicle administration, a PPI group fed the control diet with PPI administration and a YG + PPI group fed the YG diet with PPI administration. All of the groups received their respective experimental diets and daily subcutaneous injection of the vehicle or PPI for 12 weeks...
October 21, 2016: Nutrients
https://www.readbyqxmd.com/read/27763700/early-life-diets-with-prebiotics-and-bioactive-milk-fractions-attenuate-the-impact-of-stress-on-learned-helplessness-behaviours-and-alter-gene-expression-within-neural-circuits-important-for-stress-resistance
#5
Agnieszka Mika, Heidi E W Day, Alexander Martinez, Nicole L Rumian, Benjamin N Greenwood, Maciej Chichlowski, Brian M Berg, Monika Fleshner
Manipulating gut microbes may improve mental health. Prebiotics are indigestible compounds that increase the growth and activity of health-promoting microorganisms, yet few studies have examined how prebiotics affect CNS function. Using an acute inescapable stressor known to produce learned helplessness behaviours such as failure to escape and exaggerated fear, we tested whether early life supplementation of a blend of two prebiotics, galactooligosaccharide (GOS) and polydextrose (PDX), and the glycoprotein lactoferrin (LAC) would attenuate behavioural and biological responses to stress later in life...
October 20, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27720150/changes-in-the-intestinal-bacterial-community-short-chain-fatty-acid-profile-and-intestinal-development-of-preweaned-holstein-calves-1-effects-of-prebiotic-supplementation-depend-on-site-and-age
#6
J J Castro, A Gomez, B A White, H J Mangian, J R Loften, J K Drackley
Digestive disorders are common during the first few weeks of life of newborn calves. Prebiotics are nondigestible but fermentable oligosaccharides that modulate growth and activity of beneficial microbial populations, which can result in enhanced gut health and function. Galactooligosaccharides (GOS) have demonstrated such prebiotic potential. In this study, the effect of GOS supplementation on intestinal bacterial community composition and fermentation profiles; intestinal health, development, and function; and growth was evaluated in dairy calves fed for high rates of growth...
October 5, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27715472/a-novel-process-for-the-production-of-high-purity-galactooligosaccharides-gos-using-consortium-of-microbes
#7
Saravanan R, Shajahan Shubethar, Narayanan S, Manish Jain, Shankar Lade, Deepak Jadhav, Maheswaran P, Uday K Avalakki, Ashok Kumar Dubey
Galactooligosaccharides (GOS) are non-digestible dietary fibers which have a beneficial effect on human health by promoting the growth of probiotic bacteria in the gut. In addition, other health benefits have been reported from oligosaccharides consumption such as stimulation of intestinal mobility, colon cancer prevention, mineral absorption as well as protection against certain pathogenic bacterial infections. The goal of this research was to develop an efficient biotransformation system using a consortium of microbes for the production of ≥ 85% pure GOS and reusing the cell biomass in repeated cycles of biotransformation...
August 15, 2016: Preparative Biochemistry & Biotechnology
https://www.readbyqxmd.com/read/27699701/oligosaccharides-a-boon-from-nature-s-desk
#8
Seema A Belorkar, A K Gupta
This article reviews the varied sources of oligosaccharides available in nature as silent health promoting, integral ingredients of plants as well as animal products like honey and milk. The article focuses on exotic and unfamiliar oligosaccharides like Galactooligosaccharides, Lactulose derived Galactooligosaccharides, Xylooligosaccharides, Arabinooligosaccharides and algae derived Marine oligosaccharides along with the most acknowledged prebiotic fructooligosaccharides. The oligosaccharides are named as on the grounds of the monomeric units forming oligomers with functional properties...
December 2016: AMB Express
https://www.readbyqxmd.com/read/27664196/in-ovo-validation-model-to-assess-the-efficacy-of-commercial-prebiotics-on-broiler-performance-and-oxidative-stability-of-meat
#9
Giuseppe Maiorano, Katarzyna Stadnicka, Siria Tavaniello, Cinzia Abiuso, Joanna Bogucka, Marek Bednarczyk
The purpose of this study was to examine the effect of in ovo injection of 2 different prebiotics, DiNovo (DN; Laminaria spp., extract containing laminarin and fucoidan) and Bi(2)tos (BI; non-digestive trans-galactooligosaccharides from milk lactose digested with Bifidobacterium bifidum NCIMB 41171), on growth, slaughter traits, intramuscular fat percentage (IF) and muscle fiber diameter, and lipid oxidation of meat in chickens reared under commercial conditions, following an in ovo trial protocol. On d 12 of embryonic incubation, 350,560 Ross 308 eggs were randomly divided into 3 experimental groups and automatically injected in ovo with: physiological saline (control group), BI at dose of 3...
September 23, 2016: Poultry Science
https://www.readbyqxmd.com/read/27612304/an-in-vitro-approach-to-study-effects-of-prebiotics-and-probiotics-on-the-faecal-microbiota-and-selected-immune-parameters-relevant-to-the-elderly
#10
Yue Liu, Glenn R Gibson, Gemma E Walton
The aging process leads to alterations of gut microbiota and modifications to the immune response, such changes may be associated with increased disease risk. Prebiotics and probiotics can modulate microbiome changes induced by aging; however, their effects have not been directly compared. The aim of this study was to use anaerobic batch culture fermenters to assess the impact of various fermentable carbohydrates and microorganisms on the gut microbiota and selected immune markers. Elderly volunteers were used as donors for these experiments to enable relevance to an aging population...
2016: PloS One
https://www.readbyqxmd.com/read/27603970/early-life-diet-containing-prebiotics-and-bioactive-whey-protein-fractions-increased-dendritic-spine-density-of-rat-hippocampal-neurons
#11
Rosaline V Waworuntu, Taleen Hanania, Steven R Boikess, Christopher S Rex, Brian M Berg
Early life nutrition plays an important role in brain development. Emerging research in rodents, piglets and humans suggest that prebiotics, milk fat globule membrane and lactoferrin may each play unique roles in brain development and cognitive functions. However, knowledge of their combined impact is lacking. We show here that providing weanling rats with a diet containing milk fat globule membrane, lactoferrin and a polydextrose/galactooligosaccharide prebiotic blend led to a significant increase in total dendritic spine density in hippocampal dentate gyrus neurons...
September 4, 2016: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/27571098/distant-site-effects-of-ingested-prebiotics
#12
REVIEW
Stephanie Collins, Gregor Reid
The gut microbiome is being more widely recognized for its association with positive health outcomes, including those distant to the gastrointestinal system. This has given the ability to maintain and restore microbial homeostasis a new significance. Prebiotic compounds are appealing for this purpose as they are generally food-grade substances only degraded by microbes, such as bifidobacteria and lactobacilli, from which beneficial short-chain fatty acids are produced. Saccharides such as inulin and other fructo-oligosaccharides, galactooligosaccharides, and polydextrose have been widely used to improve gastrointestinal outcomes, but they appear to also influence distant sites...
2016: Nutrients
https://www.readbyqxmd.com/read/27523186/a-prebiotic-galactooligosaccharide-mixture-reduces-severity-of-hyperpnoea-induced-bronchoconstriction-and-markers-of-airway-inflammation
#13
Neil C Williams, Michael A Johnson, Dominick E Shaw, Ian Spendlove, Jelena Vulevic, Graham R Sharpe, Kirsty A Hunter
Gut microbes have a substantial influence on systemic immune function and allergic sensitisation. Manipulation of the gut microbiome through prebiotics may provide a potential strategy to influence the immunopathology of asthma. This study investigated the effects of prebiotic Bimuno-galactooligosaccharide (B-GOS) supplementation on hyperpnoea-induced bronchoconstriction (HIB), a surrogate for exercise-induced bronchoconstriction, and airway inflammation. A total of ten adults with asthma and HIB and eight controls without asthma were randomised to receive 5·5 g/d of either B-GOS or placebo for 3 weeks separated by a 2-week washout period...
September 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27508111/effect-of-probiotic-and-prebiotic-fermented-milk-on-skin-and-intestinal-conditions-in-healthy-young-female-students
#14
Naoko Mori, Mitsuyoshi Kano, Norie Masuoka, Tomoe Konno, Yumiko Suzuki, Kouji Miyazaki, Yukihide Ueki
Although persistent constipation is considered to be associated with skin problems, the supporting evidence is limited. Hence, this study investigated the effects of probiotic and prebiotic fermented milk on skin and intestinal conditions in an open-label trial. Among the 101 Japanese healthy young female students that participated, the 81 subjects in the intake group consumed a bottle of probiotic and prebiotic fermented milk containing Bifidobacterium breve strain Yakult and galactooligosaccharides daily for 4 weeks after a pre-intake period of 4 weeks, while the 20 subjects in the non-intake group did not consume the test beverage...
2016: Bioscience of Microbiota, Food and Health
https://www.readbyqxmd.com/read/27507006/food-avoidance-in-athletes-fodmap-foods-on-the-list
#15
Dana Lis, Kiran D K Ahuja, Trent Stellingwerff, Cecilia M Kitic, James Fell
We surveyed 910 athletes to assess behaviours towards self-selected food/ingredient avoidance to minimize gastrointestinal distress. Fifty-five percent eliminated at least 1 high fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) food/category, with up to 82.6% reporting symptom improvement. In athletes indicating that high FODMAP foods trigger gastrointestinal symptoms, lactose (86.5%) was most frequently eliminated, followed by galactooligosaccharides (23.9%), fructose (23...
September 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27498222/dietary-galactooligosaccharide-elicits-positive-effects-on-non-specific-immune-parameters-and-growth-performance-in-caspian-white-fish-rutilus-frisii-kutum-fry
#16
Seyed Hossein Hoseinifar, Fazel Zoheiri, Maryam Dadar, Rudabeh Rufchaei, Einar Ringø
An eight-weeks feeding trial was conducted to investigate the effects of galactooligosaccharide (GOS), on the skin and serum non-specific immune parameters and growth performance of Caspian white fish (Rutilus frisii kutum) fry. Fish (2.07 ± 0.08 g) were fed different levels of GOS (0%, 1%, 2% and 3%). No significant (P > 0.05) difference was observed in mucus protease activity, but inclusion of 1% GOS significantly (P < 0.05) elevated total immunoglobulin (Ig) level and lysozyme activity. Evaluation of serum non-specific immune parameters revealed significant (P < 0...
September 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27446157/exploitation-of-common-bean-flours-with-low-antinutrient-content-for-making-nutritionally-enhanced-biscuits
#17
Francesca Sparvoli, Monica Laureati, Roberto Pilu, Ella Pagliarini, Ivan Toschi, Gianluca Giuberti, Paola Fortunati, Maria G Daminati, Eleonora Cominelli, Roberto Bollini
Consumption of legumes is associated with a number of physiological and health benefits. Legume proteins complement very well those of cereals and are often used to produce gluten-free products. However, legume seeds often contain antinutritional compounds, such as phytate, galactooligosaccharides, phenolic compounds, lectins, enzyme inhibitors, whose presence could affect their nutritional value. Screening natural and induced biodiversity for useful traits, followed by breeding, is a way to remove undesirable components...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27403155/a-prebiotic-formula-improves-the-gastrointestinal-bacterial-flora-in-toddlers
#18
Ya-Ling Chen, Fang-Hsuean Liao, Shyh-Hsiang Lin, Yi-Wen Chien
We aimed to investigate the effect of enriched 3-prebiotic formula (including inulin, fructooligosaccharides, and galactooligosaccharides) on toddler gut health by measuring fecal microbiota. Our results revealed that the consumption of 3-prebiotic formula three times per day giving total intake of 1.8 g prebiotic ingredients significantly showed the increased number of probiotic Bifidobacterium spp. colonies and the reduced populations of both C. perfringens and total anaerobic bacteria on the fecal bacterial flora in toddlers at 18~36 months...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27360566/a-prebiotic-galactooligosaccharide-mixture-b-gos-reduces-severity-of-hyperpnea-induced-bronchoconstriction-and-airway-inflammation-1647-board-300-june-2-9-00-am-10-30-am
#19
Neil C Williams, Michael A Johnson, Dominick E Shaw, Ian Spendlove, Jelena Vulevic, Graham R Sharpe, Kirsty A Hunter
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27311434/the-effects-of-galactooligosaccharide-on-systemic-and-mucosal-immune-response-growth-performance-and-appetite-related-gene-transcript-in-goldfish-carassius-auratus-gibelio
#20
Hamed Kolangi Miandare, Shoeib Farvardin, Ali Shabani, Seyed Hossein Hoseinifar, Seyyede Sanaz Ramezanpour
The present study investigates the effects of supplementation of goldfish (Carassius auratus gibelio) diet with galactooligosaccharide (GOS) on serum immune response, mucosal immune parameters as well as appetite-related (Ghrelin) and immune-related (TNF-1α and TNF-2α) genes expression. One hundred and eighty fish with an average weight of 4.88 ± 0.28 g were stocked in twelve 500-L fiberglass tank assigned to four treatments repeated in triplicates. Fish were fed on experimental diets contain 0.5, 1 and 2% GOS for 6 weeks...
August 2016: Fish & Shellfish Immunology
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