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https://www.readbyqxmd.com/read/28801112/clinical-efficacies-of-coracoclavicular-ligament-reconstruction-using-suture-anchor-versus-hook-plate-in-the-treatment-of-distal-clavicle-fracture
#1
H W Yan, L Li, R C Wang, Y Yang, Y Xie, J Tang, Z Y Shi
INTRODUCTION: Comparison of clinical efficacies between coracoclavicular ligament reconstruction using autologous gracilis tendon with suture anchor and clavicular hook plate for the treatment of acute Neer type II distal clavicle fracture. HYPOTHESIS: Both coracoclavicular reconstruction with autologous gracilis tendon and clavicular hook plate could achieve satisfactory results for treating acute Neer type II distal clavicle fracture. METHODS: Acute Neer type II distal clavicle fracture patients enrolled in this prospective randomized study were divided into the coracoclavicular ligament reconstruction group (using autologous gracilis tendon and suture anchor) and the hook plate group...
August 8, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28797801/dimeric-and-trimeric-homo-and-heteroleptic-hydroxamic-acid-macrocycles-formed-using-mixed-ligand-fe-iii-based-metal-templated-synthesis
#2
Athavan Sresutharsan, William Tieu, Tomas Richardson-Sanchez, Cho Zin Soe, Rachel Codd
Macrocyclic hydroxamic acids coordinate Fe(III) with high affinity as part of siderophore-mediated bacterial iron acquisition. Trimeric hydroxamic acid macrocycles, such as desferrioxamine E (DFOE), are prevalent in nature, with fewer dimeric macrocycles identified, including putrebactin (pbH2), avaroferrin (avH2), bisucaberin (bsH2) and alcaligin (alH2). This work used metal-templated synthesis (MTS) to pre-assemble complexes between one equivalent of Fe(III) and two equivalents of 4-((4-aminobutyl)(hydroxy)amino)-4-oxobutanoic acid (BBH) or 4-((5-aminopentyl)(hydroxy)amino)-4-oxobutanoic acid (PBH)...
August 1, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28797282/who-should-take-care-of-me-preferences-of-old-age-individuals-for-characteristics-of-professional-long-term-caregivers-an-observational-cross-sectional-study
#3
André Hajek, Thomas Lehnert, Annemarie Wegener, Steffi G Riedel-Heller, Hans-Helmut König
BACKGROUND: It is most likely that the need for long-term care increases considerably in the next decades due to demographic shifts. Thus, we aimed at identifying the preferences for characteristics of professional long-term caregivers among old age individuals in Germany. METHODS: Data were gathered from a population-based survey of the German population aged 65 and above in 2015 (n = 1006). RESULTS: It was important for individuals in old age that long-term caregivers were 'empathetic, kind' (99...
August 10, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28776754/quantitative-two-dimensional-ultrashort-echo-time-magnetization-transfer-2d-ute-mt-imaging-of-cortical-bone
#4
Ya-Jun Ma, Anthony Tadros, Jiang Du, Eric Y Chang
PURPOSE: To investigate quantitative 2D ultrashort echo time magnetization transfer (UTE-MT) imaging in ex vivo bovine cortical bone and in vivo human tibial cortical bone. METHODS: Data were acquired from five fresh bovine cortical bone samples and five healthy volunteer tibial cortical bones using a 2D UTE-MT sequence on a clinical 3T scanner. The 2D UTE-MT sequence used four or five MT powers with five frequency offsets. Results were analyzed with a two-pool quantitative MT model, providing measurements of macromolecular fraction (f), macromolecular proton transverse relaxation times (T2m ), proton exchange rates from water/macromolecular to the macromolecular/water pool (RM0m /RM0w ), and spin-lattice relaxation rate of water pool (R1w )...
August 3, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28776339/trends-in-malignancies-among-korean-patients-infected-with-human-immunodeficiency-virus-in-the-highly-active-antiretroviral-therapy-era
#5
Shinwon Lee, Sun Hee Lee, Jeong Eun Lee, Jin Suk Kang, Seung Geun Lee, Joo Seop Chung, Ihm Soo Kwak
Since the introduction of highly active antiretroviral therapy, the life span of people with human immunodeficiency virus (HIV) or AIDS (PWHA) has been extended significantly. Therefore, the importance of non-AIDS-defining cancers (NADCs), as well as AIDS-defining cancers (ADCs) has increased. There is little information concerning the epidemiology of malignancies in PWHA in Korea. A descriptive epidemiologic study was conducted at a tertiary care hospital in Korea. PWHA who visited Pusan National University Hospital from January 2000 to October 2014 were included...
September 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28760696/simulation-training-to-improve-9-1-1-dispatcher-identification-of-cardiac-arrest-a-randomized-controlled-trial
#6
Hendrika Meischke, Ian S Painter, Scott R Stangenes, Marcia R Weaver, Carol E Fahrenbruch, Tom Rea, Anne M Turner
BACKGROUND: The objective of this study was to test the effectiveness of simulation training, using actors to make mock calls, on improving Emergency Medical Dispatchers' (EMDs) ability to recognize the need for, and reduce the time to, telephone-assisted CPR (T-CPR) in simulated and real cardiac arrest 9-1-1 calls. METHODS: We conducted a parallel prospective randomized controlled trial with n=157 EMDs from thirteen 9-1-1 call centers. Study participants were randomized within each center to intervention (i...
July 29, 2017: Resuscitation
https://www.readbyqxmd.com/read/28760181/school-physical-activity-programming-and-gross-motor-skills-in-children
#7
Ryan D Burns, You Fu, James C Hannon, Timothy A Brusseau
OBJECTIVE: We examined the effect of a comprehensive school physical activity program (CSPAP) on gross motor skills in children. METHODS: Participants were 959 children (1st-6th grade; Mean age = 9.1 ± 1.5 years; 406 girls, 553 boys) recruited from 5 low-income schools receiving a year-long CSPAP intervention. Data were collected at the beginning of the school year and at a 36-week follow-up. Gross motor skills were assessed using the Test for Gross Motor Development (3rd ed...
September 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/28759396/pictograms-units-and-dosing-tools-and-parent-medication-errors-a-randomized-study
#8
H Shonna Yin, Ruth M Parker, Lee M Sanders, Alan Mendelsohn, Benard P Dreyer, Stacy Cooper Bailey, Deesha A Patel, Jessica J Jimenez, Kwang-Youn A Kim, Kara Jacobson, Michelle C J Smith, Laurie Hedlund, Nicole Meyers, Terri McFadden, Michael S Wolf
BACKGROUND AND OBJECTIVES: Poorly designed labels and dosing tools contribute to dosing errors. We examined the degree to which errors could be reduced with pictographic diagrams, milliliter-only units, and provision of tools more closely matched to prescribed volumes. METHODS: This study involved a randomized controlled experiment in 3 pediatric clinics. English- and Spanish-speaking parents (n = 491) of children ≤8 years old were randomly assigned to 1 of 4 groups and given labels and dosing tools that varied in label instruction format (text and pictogram, or text only) and units (milliliter-only ["mL"] or milliliter/teaspoon ["mL/tsp"])...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28758628/dictyobacter-aurantiacus-gen-nov-sp-nov-a-member-of-the-family-ktedonobacteraceae-isolated-from-soil-and-emended-description-of-the-genus-thermosporothrix
#9
Shuhei Yabe, Yasuteru Sakai, Keietsu Abe, Akira Yokota, Akira Také, Atsuko Matsumoto, Arwan Sugiharto, Dwiningsih Susilowati, Moriyuki Hamada, Kazuhide Nara, I Made Sudiana, Shigeto Otsuka
A mesophilic, Gram-stain-positive, spore-forming bacterium that formed branched mycelia was isolated from paddy soil in Gunung Salak (Mount Salak), West Java, Indonesia. This strain, designated S-27T, grew at temperatures between 20 and 37 °C; the optimum growth temperature was 25 to 30 °C, and no growth was observed at 15 or 45 °C. The pH range for growth was pH 3.5 to 8.6; the optimum pH was 6.0, and no growth was observed at pH 3.0 or 9.2. Strain S-27T was able to hydrolyse polysaccharides such as starch, cellulose and xylan...
July 31, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28754436/sex-differences-in-coronary-atherosclerosis-progression-and-major-adverse-cardiac-events-in-patients-with-suspected-coronary-artery-disease
#10
Hui Gu, Yang Gao, Haiping Wang, Zhihui Hou, Lei Han, Ximing Wang, Bin Lu
BACKGROUND: Little is known about the influence of coronary atherosclerosis progression on the risk of major adverse cardiac events (MACE). Similarly, differences between men and women regarding atherosclerosis progression are poorly understood. The purpose of this study was to investigate the progression of coronary atherosclerosis by coronary CT angiography (coronary CTA) in men and women, and to evaluate its prognostic value regarding MACE. METHODS: This study included 1046 patients with suspected coronary artery disease (CAD) who underwent serial coronary CTA because of new or worsening symptoms or because follow-up coronary CTA had been recommended by attending physicians...
July 16, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28745108/comparison-of-drug-survival-and-clinical-outcome-in-patients-with-ankylosing-spondylitis-treated-with-etanercept-or-adalimumab
#11
J Ruwaard, M J l'Ami, A F Marsman, E L Kneepkens, J C van Denderen, I E van der Horst-Bruinsma, M T Nurmohamed, G Wolbink
OBJECTIVE: To compare rates of drug survival and clinical response during 2 years of follow-up in ankylosing spondylitis (AS) patients treated with etanercept or adalimumab in routine care. METHOD: Biological-naïve consecutive AS patients treated with etanercept (n = 163) or adalimumab (n = 82) were followed. Treatment discontinuation was due to inefficacy, adverse events, loss to follow-up, planning a pregnancy, or uveitis. Disease activity was assessed by the Ankylosing Spondylitis Disease Activity Score using C-reactive protein (ASDAS-CRP)...
July 26, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28742758/the-effect-of-an-adjustable-hinged-operating-table-on-lumbar-lordosis-during-lumbar-surgery
#12
Arjun Sebastian, Amin Ahmed, Brian Vernon, Emily C Nguyen, Ilyas Aleem, Michelle J Clarke, Bradford L Currier, Paul Anderson, Mohamad Bydon, Ahmad Nassr
STUDY DESIGN: Prospective observational study OBJECTIVES.: Quantify the amount of lumbar lordosis achieved on a hinged operative table in neutral, flexion, and extension. SUMMARY OF BACKGROUND DATA: Hinged operative tables may allow surgeons to adjust lumbar spine positioning intraoperatively. The amount of lumbar lordosis in neutral, flexion, and extension positions has not been quantified prospectively using a hinged table. METHODS: Thirty patients undergoing elective lumbar surgery were enrolled...
July 24, 2017: Spine
https://www.readbyqxmd.com/read/28729910/drug-induced-gingival-hyperplasia-a-retrospective-study-using-spontaneous-reporting-system-databases
#13
Haruna Hatahira, Junko Abe, Yuuki Hane, Toshinobu Matsui, Sayaka Sasaoka, Yumi Motooka, Shiori Hasegawa, Akiho Fukuda, Misa Naganuma, Tomofumi Ohmori, Yasutomi Kinosada, Mitsuhiro Nakamura
BACKGROUND: Drug-induced gingival hyperplasia (DIGH) causes problems with chewing, aesthetics, and pronunciation, and leads to the deterioration of the patient's quality of life (QOL). Thus, the aim of this study was to evaluate the incidence of DIGH using spontaneous reporting system (SRS) databases. METHODS: We analyzed reports of DIGH from SRS databases and calculated the reporting odds ratios (RORs) of suspected drugs (immunosuppressants, calcium channel blockers, and anticonvulsants)...
2017: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/28721135/a-comprehensive-guidelines-based-approach-reduces-cardiovascular-risk-in-everyday-practice-the-varo-study
#14
Tomáš Štulc, Věra Lánská, Michaela Šnejdrlová, Michal Vrablík, Martina Prusíková, Richard Češka
INTRODUCTION: The aim of study was to investigate the possibility of cardiovascular risk improvement through systematic identification of high-risk individuals and treatment in accordance with current guidelines using modern therapy in daily clinical practice. MATERIAL AND METHODS: Two hundred and sixty-three physicians participated in the study. The physicians were asked to screen for cardiovascular risk factors in patients presenting with unrelated problems and to re-evaluate the attainment of treatment goals in those with already known risk factors...
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28721109/association-of-social-support-with-gratitude-and-sense-of-coherence-in-japanese-young-women-a-cross-sectional-study
#15
Tomoko Fujitani, Kumiko Ohara, Katsuyasu Kouda, Tomoki Mase, Chiemi Miyawaki, Katsumasa Momoi, Yoshimitsu Okita, Maki Furutani, Harunobu Nakamura
PURPOSE: Recent studies have shown that perceived social support is associated with gratitude and sense of coherence, but evidence for this concept remains scarce. In the present study, we investigated relationships between social support, gratitude, and sense of coherence, focusing on the construct of and source of social support among young women. METHODS: The study was conducted in 2014 in Japan. Participants comprised 208 female university students (aged 19...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28717922/healthy-living-behaviors-among-chinese-american-preschool-aged-children-results-of-a-parent-survey
#16
Virginia Rall Chomitz, Alison Brown, Victoria Lee, Aviva Must, Kenneth Kwan Ho Chui
Associations between diet, physical activity, parenting, and acculturation among Chinese-American children are understudied. Parents/caregivers of children attending child-care programs in Boston Chinatown completed a self-administered survey on demographics, child's diet, physical activities, anthropometrics, and parenting practices. Associations were evaluated in multivariable regression analysis, stratified by survey language preference, a proxy for acculturation. Responding Asian families = 132; 86...
July 17, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28696231/comparison-of-plasma-and-intrapulmonary-concentrations-of-nafithromycin-wck-4873-in-healthy-adult-subjects
#17
Keith A Rodvold, Mark H Gotfried, Rakesh Chugh, Mugdha Gupta, H David Friedland, Ashima Bhatia
Nafithromycin concentrations in plasma, epithelial lining fluid (ELF), and alveolar macrophage (AM) of 37 healthy adult subjects were measured following repeated dosing of oral nafithromycin 800 mg once daily for three days. Noncompartmental pharmacokinetic (PK) parameters were determined from serial plasma samples collected over a 24-hour interval following the first and third oral doses. Each subject underwent one standardized bronchoscopy with bronchoalveolar lavage (BAL) at 3, 6, 9, 12, 24 or 48 hours after the third dose of nafithromycin...
July 10, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28687420/hepatic-adverse-event-profile-of-inotuzumab-ozogamicin-in-adult-patients-with-relapsed-or-refractory-acute-lymphoblastic-leukaemia-results-from-the-open-label-randomised-phase-3-ino-vate-study
#18
Hagop M Kantarjian, Daniel J DeAngelo, Anjali S Advani, Matthias Stelljes, Partow Kebriaei, Ryan D Cassaday, Akil A Merchant, Naohito Fujishima, Toshiki Uchida, Maria Calbacho, Anna A Ejduk, Susan M O'Brien, Elias J Jabbour, Hui Zhang, Barbara J Sleight, Erik R Vandendries, David I Marks
BACKGROUND: The INO-VATE study demonstrated efficacy and safety of inotuzumab ozogamicin versus standard care in adults with relapsed or refractory B-cell acute lymphoblastic leukaemia. Here, we report the frequency of, and potential risk factors for, hepatotoxicity in patients in this trial and after treatment and subsequent haemopoietic stem-cell transplantation (HSCT). METHODS: In this open-label, phase 3, multicentre, international study, adults with relapsed or refractory, CD22-positive, Philadelphia chromosome (Ph)-positive or Ph-negative B-cell acute lymphoblastic leukaemia who were due to receive first or second salvage treatment were randomly assigned (1:1) via an interactive voice response system to receive inotuzumab ozogamicin (starting dose 1·8 mg/m(2) per cycle [0·8 mg/m(2) on day 1; 0·5 mg/m(2) on days 8 and 15 of a 21-28 day cycle for ≤6 cycles]) or standard care (either fludarabine plus cytarabine plus granulocyte colony-stimulating factor, mitoxantrone plus cytarabine, or high-dose cytarabine)...
July 4, 2017: Lancet Haematology
https://www.readbyqxmd.com/read/28681645/mean-platelet-volume-in-pemphigus-vulgaris
#19
Khalaf Kridin, Wesal Shihade, Shira Zelber-Sagi
Pemphigus vulgaris (PV) is an autoimmune blistering disease of the skin and mucous membranes. The mean platelet volume (MPV) is an index of platelet activation reported to be influenced by inflammation. We investigated the MPV in patients with PV relative to controls. This case-control study included 160 patients with PV and 640 age- and sex-matched controls. The MPV, platelet count, and other inflammatory parameters were measured for all study participants. A significantly decreased MPV was observed in patients with PV compared with controls, 9...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28678305/clinical-features-and-surgical-outcome-of-triad-exotropia
#20
Suk-Gyu Ha, Young-Woo Suh, Seung-Hyun Kim
PURPOSE: To describe the clinical features and surgical outcome of A-pattern exotropia combined with dissociated vertical deviation and superior oblique overaction. METHODS: The medical records of patients with A-pattern exotropia combined with dissociated vertical deviation and superior oblique overaction who underwent horizontal muscle surgery alone or in combination with superior oblique muscle weakening surgery were retrospectively reviewed. The patients were divided into two groups according to their surgery: the horizontal muscle surgery alone group and the horizontal muscle surgery with bilateral superior oblique weakening surgery (combined surgery) group...
July 5, 2017: Journal of Pediatric Ophthalmology and Strabismus
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