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https://www.readbyqxmd.com/read/28540570/magnesium-supplementation-and-the-effects-on-wound-healing-and-metabolic-status-in-patients-with-diabetic-foot-ulcer-a-randomized-double-blind-placebo-controlled-trial
#1
Reza Razzaghi, Farangis Pidar, Mansooreh Momen-Heravi, Fereshteh Bahmani, Hossein Akbari, Zatollah Asemi
Hypomagnesemia is associated with the development of neuropathy and abnormal platelet activity, both of which are risk factors for diabetic foot ulcer (DFU). This study was carried out to evaluate the effects of magnesium administration on wound healing and metabolic status in subjects with DFU. This randomized, double-blind, placebo-controlled trial was performed among 70 subjects with grade 3 DFU. Subjects were randomly divided into two groups (35 subjects each group) to receive either 250 mg magnesium oxide supplements or placebo daily for 12 weeks...
May 24, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28530485/energy-requirement-assessment-in-japanese-table-tennis-players-using-the-doubly-labeled-water-method
#2
Hiroyuki Sagayama, Genki Hamaguchi, Makiko Toguchi, Mamiko Ichikawa, Yosuke Yamada, Naoyuki Ebine, Yasuki Higaki, Hiroaki Tanaka
Total daily energy expenditure (TEE) and physical activity level (PAL) are important for adequate nutritional management in athletes. The PAL of table tennis has been estimated to about 2.0: it is categorized as a moderate-activity sport (4.0 metabolic equivalents [METs]) in the Compendium of Physical Activities. However, modern table tennis makes high physiological demands. The aims of the present study were to examine (1) TEE and PAL of competitive table tennis players and (2) the physiological demands of various types of table tennis practice...
May 22, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28526346/release-study-and-inhibitory-activity-of-thyme-essential-oil-loaded-chitosan-nanoparticles-and-nanocapsules-against-foodborne-bacteria
#3
M Sotelo-Boyás, Z Correa-Pacheco, S Bautista-Baños, Y Gómez Y Gómez
The antibacterial property of thyme essential oil due to different volatile compounds, has been well documented in the literature. To overcome the high volatility of essential oil components, encapsulation has emerged as a new alternative. In this work, chitosan and thyme essential oil-loaded chitosan nanoparticles (TEO-CSNPs) and nanocapsules (TEO-CSNCs) were prepared by nanoprecipitation and nanoencapsulation, respectively. The morphology, encapsulation efficiency, release kinetics, and inhibitory activity were evaluated...
May 16, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28526090/reduced-hdac2-in-skeletal-muscle-of-copd-patients
#4
Masako To, Elisabeth B Swallow, Kenich Akashi, Kosuke Haruki, S Amanda Natanek, Michael I Polkey, Kazuhiro Ito, Peter J Barnes
BACKGROUND: Skeletal muscle weakness in chronic obstructive pulmonary disease (COPD) is an important predictor of poor prognosis, but the molecular mechanisms of muscle weakness in COPD have not been fully elucidated. The aim of this study was to investigate the role of histone deacetylases(HDAC) in skeletal muscle weakness in COPD. METHODS AND RESULTS: Twelve COPD patients, 8 smokers without COPD (SM) and 4 healthy non-smokers (NS) were recruited to the study. HDAC2 protein expression in quadriceps muscle biopsies of COPD patients (HDAC2/β-actin: 0...
May 19, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28525482/artificial-cervical-disk-replacement-for-the-treatment-of-adjacent-segment-disease-after-anterior-cervical-decompression-and-fusion
#5
Sheng Bin, Huang Xiangwang, Xiao Sheng, Xiang Tiecheng, Liu Xiangyang, Zhang Yi, Liu Bin
STUDY DESIGN: Retrospective study. OBJECTIVE: To evaluate the outcome of artificial cervical disk replacement (ACDR) for the treatment of adjacent segment disease (ASD) after anterior cervical decompression and fusion (ACDF). SUMMARY OF BACKGROUND DATA: ACDF is the useful procedure for degenerative cervical diseases. However, studies have reported accelerated degeneration of functional spinal units adjacent to the fusion site after ACDF. MATERIALS AND METHODS: Between January 2004 and January 2011, 32 inpatients (18 male, 14 female; age, 38-61 y; mean, 48 y) underwent ACDR for the treatment of ASD after previous ACDF (single-level: n=12; 2-level: n=15; 3-level: n=5)...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28513218/three-cycles-of-radiofrequency-ablation-are-more-efficacious-than-two-in-the-management-of-morton-s-neuroma
#6
David Brooks, Adam Parr, William Bryceson
BACKGROUND: Morton's neuroma is a common cause of forefoot pain. Outcomes of conservative therapy are mixed and many patients undergo operative intervention. Radiofrequency ablation has recently gained favor as a treatment option, although the optimal regime is unknown. This study investigates the effectiveness of 2 versus 3 cycles of radiofrequency ablation for the treatment of Morton's neuroma. METHODS: We surveyed a cohort of patients with Morton's neuroma who had progressed to radiofrequency ablation after failed conservative treatment...
May 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28503504/antioxidant-status-and-risk-of-gestational-diabetes-mellitus-a-case-control-study
#7
Vida Mohammad Parast, Zamzam Paknahad
Gestational diabetes mellitus (GDM) is described as glucose intolerance diagnosed during pregnancy. Increased oxidative stress has implicated in diabetic problems. The aim of the current study was to compare antioxidant capacity and antioxidant nutrient intake between women with GDM (n = 40) and healthy pregnant women (n = 40). Demographic and obstetrics data were completed using interview technique and dietary intakes by using a semi-quantitative food frequency questionnaire (FFQ) with 168 items. The total antioxidant capacity (TAC) of serum was assessed by double-antibody sandwich enzyme-linked immune-sorbent assay (ELISA) method...
April 2017: Clinical Nutrition Research
https://www.readbyqxmd.com/read/28491086/left-univentricular-pacing-for-cardiac-resynchronization-therapy-using-rate-adaptive-atrioventricular-delay
#8
Li-Jin Pu, Yu Wang, Lu-Lu Zhao, Tao Guo, Shu-Min Li, Bao-Tong Hua, Ping Yang, Jun Yang, Yan-Zhou Lu, Liu-Qing Yang, Ling Zhao, Hai-Yun Luo
OBJECTIVE: To evaluate left univentricular (LUV) pacing for cardiac resynchronization therapy (CRT) using a rate-adaptive atrioventricular delay (RAAVD) algorithm to track physiological atrioventricular delay (AVD). METHODS: A total of 72 patients with congestive heart failure (CHF) were randomized to RAAVD LUV pacing versus standard biventricular (BiV) pacing in a 1: 1 ratio. Echocardiography was used to optimize AVD for both groups. The effects of sequential BiV pacing and LUV pacing with optimized A-V (right atrio-LV) delay using an RAAVD algorithm were compared...
February 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28490759/comorbidity-burden-of-patients-with-parkinson-s-disease-and-parkinsonism-between-2003-and-2012-a-multicentre-nationwide-retrospective-study-in-china
#9
Xin Wang, Fan Zeng, Wang-Sheng Jin, Chi Zhu, Qing-Hua Wang, Xian-Le Bu, Hong-Bo Luo, Hai-Qiang Zou, Jie Pu, Zhong-He Zhou, Xiao-Ping Cui, Qing-Song Wang, Xiang-Qun Shi, Wei Han, Qiang Wu, Hui-Sheng Chen, Hang Lin, Li-Li Zhang, Meng Zhang, Yan Lian, Zhi-Qiang Xu, Hua-Dong Zhou, Tao Zhang, Yan-Jiang Wang
Parkinson's disease (PD) and Parkinsonism are common neurodegenerative disorders with continuously increasing prevalence, causing high global burdens. However, data concerning the comorbidity burden of patients with PD or Parkinsonism in China are lacking. To investigate the health condition and comorbidity burden, a total of 3367 PD and 823 Parkinsonism patients were included from seven tertiary hospitals in seven cities across China from 2003 to 2012. Their comorbidity burden was collected and quantified by the Elixhauser Comorbidity Index (ECI) and Charlson Comorbidity Index (CCI)...
May 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28481722/ems-provider-perceptions-on-termination-of-resuscitation-in-a-large-urban-ems-system
#10
Katie L Tataris, Christopher T Richards, Leslee Stein-Spencer, Stephanie Ryan, Pete Lazzara, Joseph M Weber
OBJECTIVE: Despite the value of out-of-hospital Termination of Resuscitation (TOR) and the scientific evidence in favor of this practice, TOR has not been uniformly adopted or consistently practiced in EMS systems. Previous focus group studies have identified multiple barriers to implementation of out of hospital TOR but existing literature on EMS provider perceptions is limited. We sought to identify EMS providers' perceived barriers to performing out-of-hospital TOR in a large urban EMS system...
May 8, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28481126/increased-levels-of-alveolar-and-airway-exhaled-nitric-oxide-in-runners
#11
Alexandra Thornadtsson, Nikola Drca, Fabio Ricciardolo, Marieann Högman
AIM: The objective of this study was to apply extended NO analysis for measurements of NO dynamics in the lung, divided into alveolar and airway contribution, in amateur runners and marathoners. METHODS: The athletes participated in either a marathon or a half marathon. The athletes self-reported their age, weight, height, training distance per week, competing distance, cardio-pulmonary health, atopic status, and use of tobacco. Measurements of exhaled NO (FENO) with estimation of alveolar NO (CANO) and airway flux (JawNO), ventilation, pulse oximetry, and peak flow were performed before, immediately after, and 1 hour after completing the race...
May 8, 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28467124/building-capacity-in-healthcare-by-re-examining-clinical-services-in-paramedicine
#12
Walter Tavares, Ian Drennan, Kelly Van Diepen, Michael Abanil, Natalie Kedzierski, Chris Spearen, Norm Barrette, Mathew Mercuri
OBJECTIVES: Emergency departments (ED) continue to be overburdened, leading to crowding and elevated risk of negative clinical outcomes. Extending clinical services to paramedics may support efforts to improve ED burdens by promoting health care access and capacity during times of patient crisis. The objective of this study was to identify the clinical course and most responsible diagnosis of patients transported by paramedic services to local EDs to then evaluate impact of various augmented 9-1-1/paramedic clinical service models on the need for additional ED services...
May 3, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28459350/positive-effects-of-augmented-feedback-to-reduce-time-on-ground-in-well-trained-runners
#13
Rahel Gilgen-Ammann, Thomas Wyss, Severin Troesch, Louis Heyer, Wolfgang Taube
PURPOSE: Successful elite sprint to long-distance runners are known to have shorter ground contact times (GCT) than their less successful counterparts. The purpose of this study was to investigate whether augmented feedback (aF) about GCT can reduce the time on ground (TOG) per minute in long-distance runners and if so, whether this reduction improves running performance. METHODS: Thirty well-trained runners were allocated to three groups. The intervention group (IG) received visual aF about their GCT during eight high-intensity interval sessions in the 4-week training period and were instructed to minimize GCT...
May 1, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28459159/a-comparison-of-time-delay-in-three-continuous-glucose-monitors-for-adolescents-and-adults
#14
Manasi Sinha, Katherine M McKeon, Savan Parker, Laura G Goergen, Hui Zheng, Firas H El-Khatib, Steven J Russell
BACKGROUND: The physiologic delay in glucose diffusion from the blood to the interstitial fluid and instrumental factors contribute to the delay between changes in plasma glucose (PG) and measurements made by continuous glucose monitors (CGMs). This study compared the duration of this delay for three CGMs. METHODS: A total of 24 healthy adolescent and adult subjects with type 1 diabetes wore three CGM devices simultaneously for 48 hours: Dexcom G4 Platinum, Abbott Navigator, and Medtronic Enlite...
April 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28448557/are-sex-differences-in-fundamental-motor-skills-uniform-throughout-the-entire-preschool-period
#15
Jakub Kokštejn, Martin Musálek, James J Tufano
The aim of this study was to assess differences in fundamental motor skills (FMS) proficiency between boys and girls of each age group, independently, across the entire preschool period. Using the Movement Assessment Battery for Children-second edition, FMS proficiency was tested in 325 preschoolers (4.9 ± 1.1 y, range 3-6) using a cross-sectional design. Compared to boys of the same age, 3- and 4-year-old girls had greater total (p < .01), fine motor skill (p < .01), and balance scores (p < .05)...
2017: PloS One
https://www.readbyqxmd.com/read/28445855/speed-dependent-effects-of-laterally-wedged-insoles-on-gait-biomechanics-in-healthy-subjects
#16
Felix Kluge, Sebastian Krinner, Matthias Lochmann, Bjoern M Eskofier
Laterally wedged insoles have been shown to be effective for the reduction of the knee adduction moment and other biomechanical variables that are associated with the pathogenesis of knee osteoarthritis. However, inconclusive results such as adverse effects in individual subjects or even no group-wise wedge effects have been presented in different studies and it has been suggested to identify variables that potentially confound the wedge effect. The main objective of this study was the investigation of interaction effects of lateral wedges with walking speed, as different self-selected speeds have mainly been used in previous studies...
April 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28445224/impact-of-6-consecutive-days-of-sprint-training-in-hypoxia-on-performance-in-competitive-sprint-runners
#17
Nobukazu Kasai, Sahiro Mizuno, Sayuri Ishimoto, Etsuko Sakamoto, Misato Maruta, Toshiyuki Kurihara, Yuko Kurosawa, Kazushige Goto
The purpose of the present study was to determine the effects of 6 successive days of repeated sprint training in moderate hypoxia on anaerobic capacity in 100-200-m sprint runners. Eighteen male sprint runners (age, 20.0 ± 0.3 years; height, 175.9 ± 1.1 cm; body mass, 65.0 ± 1.2 kg) performed repeated cycling sprints for 6 consecutive days in either normoxic (NOR; fraction of inspired oxygen [FiO2], 20.9%; n = 9) or hypoxic conditions (HYPO; FiO2, 14.5%; n = 9). The repeated sprint ability (10 × 6-s sprints), 30-s maximal sprint ability, maximal oxygen uptake (VO2max), and 60-m running time on the track were measured before and after the training period...
April 18, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28445110/normobaric-hypoxia-increases-the-growth-hormone-response-to-maximal-resistance-exercise-in-trained-men
#18
Dean Filopoulos, Stuart J Cormack, Douglas G Whyte
This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82 ± 2%) and normoxia (NOR; FiO2 0.21, SpO2 98 ± 0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum...
April 26, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28432109/early-response-to-ranibizumab-predictive-of-functional-outcome-after-dexamethasone-for-unresponsive-diabetic-macular-oedema
#19
Maria Vittoria Cicinelli, Michele Cavalleri, Lea Querques, Alessandro Rabiolo, Francesco Bandello, Giuseppe Querques
PURPOSE: To analyse the effects of intravitreal dexamethasone implant in patients suffering from diabetic macular oedema (DME) on the basis of their visual and functional response to antivascular endothelial growth factor (VEGF) loading dose, in order to early shift to corticosteroids in poorly responding patients. DESIGN: Retrospective monocentric study. METHODS: Data of patients with diabetes shifted to 0.7 mg dexamethasone implant after three injections of ranibizumab (RNB) and followed-up to 12 months were reviewed...
April 21, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28428759/morphological-regeneration-and-functional-recovery-of-neuromuscular-junctions-after-tourniquet-induced-injuries-in-mouse-hindlimb
#20
Huiyin Tu, Dongze Zhang, Ryan M Corrick, Robert L Muelleman, Michael C Wadman, Yu-Long Li
Tourniquet application and its subsequent release cause serious injuries to the skeletal muscle, nerve, and neuromuscular junction (NMJ) due to mechanical compression and ischemia-reperfusion (IR). Monitoring structural and functional repair of the NMJ, nerve, and skeletal muscle after tourniquet-induced injuries is beneficial in exploring potential cellular and molecular mechanisms responsible for tourniquet-induced injuries, and for establishing effective therapeutic interventions. Here, we observed long-term morphological and functional changes of the NMJ in a murine model of tourniquet-induced hindlimb injuries...
2017: Frontiers in Physiology
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