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https://www.readbyqxmd.com/read/29143731/the-treatment-of-depression-in-primary-care
#1
Sebastian Trautmann, Katja Beesdo-Baum
BACKGROUND: General practitioners play a key role in the care of patients with depressive disorders. We studied the frequency and type of treatment of depressive disorders in primary care. METHODS: In a cross-sectional epidemiological study on a particular day in six different regions in Germany, 253 physicians and 3563 unselected patients were asked to fill in a questionnaire assessing the diagnosis and treatment of depression. A total of 3431 usable patient data sets and 3211 sets of usable data from both the patient and the physician were subjected to further analysis...
October 27, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29140748/paramedic-initiated-home-care-referrals-and-use-of-home-care-and-emergency-medical-services
#2
Amol A Verma, John Klich, Adam Thurston, Jordan Scantlebury, Alex Kiss, Gayle Seddon, Samir K Sinha
OBJECTIVE: We examined the association between paramedic-initiated home care referrals and utilization of home care, 9-1-1, and Emergency Department (ED) services. METHODS: This was a retrospective cohort study of individuals who received a paramedic-initiated home care referral after a 9-1-1 call between January 1, 2011 and December 31, 2012 in Toronto, Ontario, Canada. Home care, 9-1-1, and ED utilization were compared in the 6 months before and after home care referral...
November 15, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29138143/minimally-invasive-stand-alone-cox-maze-procedure-for-persistent-and-long-standing-persistent-atrial-fibrillation-perioperative-safety-and-5-year-outcomes
#3
Niv Ad, Sari D Holmes, Ted Friehling
BACKGROUND: Rhythm control is challenging in patients with extended atrial fibrillation (AF) duration and persistent/long-standing persistent AF. Among surgical approaches to treat AF, the Cox maze procedure performed using alternative energy sources remains superior to other beating heart techniques. We examined permanence of safety and success for the on-pump, minimally invasive, stand-alone Cox maze procedure 5 years after surgery. METHODS AND RESULTS: Stand-alone, right 5 cm minithoracotomy, Cox maze III/IV procedure for nonparoxysmal AF was conducted in 133 patients (mean follow-up=65±34 months)...
November 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29136152/concomitant-thoracoscopic-surgery-for-solitary-pulmonary-nodule-and-atrial-fibrillation
#4
Rongxin Lu, Ju Mei, Dongfang Zhao, Zhaolei Jiang, Haibo Xiao, Mingsong Wang, Nan Ma
OBJECTIVES: The incidence of both solitary pulmonary nodules (SPN) and non-valvular atrial fibrillation (NVAF) has increased over the past decade. We performed concomitant video-assisted thoracoscopic surgery with modified epicardial radiofrequency ablation procedure for NVAF and SPN resection. METHODS: Sixteen patients (7 men, mean age 62.6 ± 11.2 years) with SPN and NVAF underwent this procedure. Of these patients, 10 had paroxysmal atrial fibrillation and 6 persistent atrial fibrillation...
November 10, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29132455/going-beyond-the-9-1-1-call-what-bc-emergency-health-services-is-doing-to-improve-timely-access-to-emergency-care
#5
Kerry Campbell, Jessica Jaiven, Kimberly Banfield, Corinne Begg, Janice Butler, Leanne Thain
British Columbia Emergency Health Services (BCEHS) uses an internationally recognized Medical Priority Dispatch System to assign appropriate responses to 9-1-1 calls based on patients' clinical acuity. In 2015, 71% of Omega calls (classified as calls involving low acuity injuries) were assigned an ambulance. To better meet patients' needs, BCEHS collaborated with HealthLink BC's Nursing Services (HLBC NS) to audit over 2,000 calls. Based on the results, three Plan, Do, Study, Act (PDSA) cycles were implemented, yielding a 35% decrease in ambulances assigned and a 173% increase in referrals to HLBC NS to provide more suitable support...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/29129470/risk-stratification-for-surgical-outcomes-in-older-colorectal-cancer-patients-using-isar-hp-and-g8-screening-tools
#6
Esteban T D Souwer, Norbert M Verweij, Frederiek van den Bos, Esther Bastiaannet, Rob M E Slangen, Willem H Steup, Marije E Hamaker, Johanna E A Portielje
BACKGROUND: Older patients are at risk for adverse outcomes after surgical treatment of cancer. Identifying patients at risk could affect treatment decisions and prevent functional decline. Screening tools are available to select patients for Geriatric Assessment. Until now their predictive value for adverse outcomes in older colorectal cancer patients has not been investigated. OBJECTIVE: To study the predictive value of the Geriatric 8 (G8) and Identification of Seniors at Risk for Hospitalized Patients (ISAR-HP) screening tools for adverse outcomes after elective colorectal surgery in patients older than 70years...
November 9, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29126871/lumacaftor-ivacaftor-in-patients-with-cystic-fibrosis-and-advanced-lung-disease-homozygous-for-f508del-cftr
#7
Jennifer L Taylor-Cousar, Manu Jain, Tara Lynn Barto, Tarik Haddad, Jeffrey Atkinson, Simon Tian, Rui Tang, Gautham Marigowda, David Waltz, Joseph Pilewski
OBJECTIVE: Evaluation of the safety, tolerability, and efficacy of lumacaftor/ivacaftor in patients with cystic fibrosis (CF) with severe lung disease. METHODS: Patients with CF 12 years of age and older, homozygous for F508del-CFTR, with percent predicted forced expiratory volume in 1 second (ppFEV1) <40 received lumacaftor 400 mg/ivacaftor 250mg every 12h (full dose) for 24weeks in an open-label, prospective study (NCT02390219). Dose modification to half dose for 1-2weeks (including at initiation) was permitted...
November 7, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/29124288/the-medial-tibial-joint-line-elevation-over-5%C3%A2-mm-restrained-the-improvement-of-knee-extension-angle-in-unicompartmental-knee-arthroplasty
#8
Koji Takayama, Kazunari Ishida, Hirotsugu Muratsu, Yuichi Kuroda, Masanori Tsubosaka, Shingo Hashimoto, Shinya Hayashi, Takehiko Matsushita, Takahiro Niikura, Ryosuke Kuroda, Tomoyuki Matsumoto
PURPOSE: The purpose of this study was to examine the relationship between medial tibial joint line elevation and the improvement of range of motion (ROM) in unicompartmental knee arthroplasty (UKA). The hypothesis was that limited elevation of tibial joint line will improve knee range of motion in UKA. METHODS: Forty-six consecutive medial UKAs were enrolled in this study. Medial tibial joint line elevation was defined as the polyethylene insert and tibial tray thickness minus the tibial osteotomy and sawblade thickness...
November 9, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29121084/fission-yeast-strains-with-circular-chromosomes-require-the-9-1-1-checkpoint-complex-for-the-viability-in-response-to-the-anti-cancer-drug-5-fluorodeoxyuridine
#9
Hossain Mohammad Shamim, Yukako Minami, Daiki Tanaka, Shinobu Ukimori, Johanne M Murray, Masaru Ueno
Thymidine kinase converts 5-fluorodeoxyuridine to 5-fluorodeoxyuridine monophosphate, which causes disruption of deoxynucleotide triphosphate ratios. The fission yeast Schizosaccharomyces pombe does not express endogenous thymidine kinase but 5-fluorodeoxyuridine inhibits growth when exogenous thymidine kinase is expressed. Unexpectedly, we found that 5-fluorodeoxyuridine causes S phase arrest even without thymidine kinase expression. DNA damage checkpoint proteins such as the 9-1-1 complex were required for viability in the presence of 5-fluorodeoxyuridine...
2017: PloS One
https://www.readbyqxmd.com/read/29118197/control-of-saccadic-latency-in-a-dynamic-environment-allocation-of-saccades-in-time-follows-the-matching-law
#10
Cécile Vullings, Laurent Madelain
When exploring the visual environment, one uses saccades to shift gaze and fixation to gather spatially and temporally localized information. We propose that the temporal structure of our environment should constrain the temporal allocation of saccades. Here, we probe the possibility of learning to control saccadic latencies in a choice paradigm. Six participants made saccades within 80-300ms following a target horizontally stepping by 10 deg between two fixed locations. For each participant we constructed two classes of latencies, "short" and "long", using the first and last quartiles of the individual baseline distribution (e...
November 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29100764/arthroscopic-versus-open-iliac-crest-bone-grafting-in-recurrent-anterior-shoulder-instability-with-glenoid-bone-loss-a-computed-tomography-based-quantitative-assessment
#11
Lukas Ernstbrunner, Fabian Plachel, Philipp Heuberer, Leo Pauzenberger, Philipp Moroder, Herbert Resch, Werner Anderl
PURPOSE: To assess the iliac crest bone graft (ICBG) position in the en-face view and axial plane comparing arthroscopic with open procedures. METHODS: A total of 40 consecutive patients with recurrent anterior shoulder instability and glenoid bone loss over 10% treated by 2 independent orthopaedic departments were included. Two independent observers analyzed preoperative and immediate postoperative computed tomography scans of 20 open (group O) and 20 arthroscopic (group A) procedures...
October 31, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29090904/boosting-electrical-performance-of-high-%C3%AE%C2%BA-nanomultilayer-dielectrics-and-electronic-devices-by-combining-solution-combustion-synthesis-and-uv-irradiation
#12
Emanuel Carlos, Rita Branquinho, Asal Kiazadeh, Jorge Martins, Pedro Barquinha, Rodrigo Martins, Elvira Fortunato
In the past decade, solution-based dielectric oxides have been widely studied in electronic applications enabling the use of low-cost processing technologies and device improvement. The most promising are the high-κ dielectrics, like aluminum (AlOx) and hafnium oxide (HfOx), that allow an easier trap filling in the semiconductor and the use of low operation voltage. However, in the case of HfOx, a high temperature usually is needed to induce a uniform and condensed film, which limits its applications in flexible electronics...
November 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29076963/mechanical-and-metabolic-responses-to-traditional-and-cluster-set-configurations-in-the-bench-press-exercise
#13
Amador García-Ramos, Jorge M González-Hernández, Ezequiel Baños-Pelegrín, Adrián Castaño-Zambudio, Fernando Capelo-Ramírez, Daniel Boullosa, Guy G Haff, Pedro Jiménez-Reyes
García-Ramos, A, González-Hernández, JM, Baños-Pelegrín, E, Castaño-Zambudio, A, Capelo-Ramírez, F, Boullosa, D, Haff, GG, and Jiménez-Reyes, P. Mechanical and metabolic responses to traditional and cluster set configurations in the bench press exercise. J Strength Cond Res XX(X): 000-000, 2017-This study aimed to compare mechanical and metabolic responses between traditional (TR) and cluster (CL) set configurations in the bench press exercise. In a counterbalanced randomized order, 10 men were tested with the following protocols (sets × repetitions [inter-repetition rest]): TR1: 3 × 10 (0-second), TR2: 6 × 5 (0-second), CL5: 3 × 10 (5-second), CL10: 3 × 10 (10-second), and CL15: 3 × 10 (15-second)...
October 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29075842/superior-biomechanical-properties-and-tying-time-with-the-modified-prusik-knot-and-wittstein-suture-loop-to-the-krackow-stitch
#14
Chih-Kai Hong, Cheng-Li Lin, Jui-Ming Yang, Chien-An Shih, Yi-Chuan Chou, Ming-Long Yeh, Chen-Hao Chiang, Wei-Ren Su
INTRODUCTION: The purposes of the study were to compare (1) the biomechanical properties of the modified Prusik knot, Wittstein suture loop, and Krackow stitch fixation, and (2) the knot tying times for tendon graft fixation among the Krackow stitch, modified rolling hitch, modified Prusik knot, and Wittstein suture loop. MATERIALS AND METHODS: First, 33 fresh-frozen porcine flexor profundus tendons were randomly divided into three groups of 11 specimens. The experimental procedure was designed to assess elongation of the suture-tendon construct across the modified Prusik knot, Wittstein suture loop, and the Krackow stitch...
October 26, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29071237/the-effect-of-daily-versus-weekly-levothyroxine-replacement-on-thyroid-function-test-in-hypothyroid-patients-at-a-tertiary-care-centre-in-haryana
#15
Rajesh Rajput, Vaibhav Pathak
OBJECTIVE: We compare the effect of daily versus weekly levothyroxine (LT4) replacement on thyroid function test (TFT) in hypothyroid patients at a tertiary care centre in Haryana. MATERIALS AND METHODS: This was a randomised crossover study in which 100 hypothyroid patients on a stable LT4 dose were divided into 2 groups of 50 each. In group I, patients were given daily therapy for 6 weeks and then shifted to weekly therapy for the next 6 weeks. In group II, patients were given LT4 once a week for 6 weeks and then switched to daily therapy for the next 6 weeks...
September 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29069048/predictive-factors-associated-with-neck-pain-in-patients-with-cervical-disc-degeneration-a-cross-sectional-study-focusing-on-modic-changes
#16
Lingde Kong, Weifeng Tian, Peng Cao, Haonan Wang, Bing Zhang, Yong Shen
The predictive factors associated with neck pain remain unclear. We conducted a cross-sectional study to assess predictive factors, especially Modic changes (MCs), associated with the intensity and duration of neck pain in patients with cervical disc degenerative disease.We retrospectively reviewed patients in our hospital from January 2013 to December 2016. Severe neck pain (SNP) and persistent neck pain (PNP) were the 2 main outcomes, and were assessed based on the numerical rating scale (NRS). Basic data, and also imaging data, were collected and analyzed as potential predictive factors...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29066373/obesity-body-image-and-its-impact-on-children-s-eating-and-exercise-behaviors-in-china-a-nationwide-longitudinal-study
#17
Jungwon Min, Alice Fang Yan, Vivian H C Wang, Youfa Wang
Body image seems to mediate the association between obesity and health behaviors as well as weight control attempts. We examined the distribution of children's body image by demographic characteristics and their subsequent associations with eating, exercise, and weight change. Child body image and health behaviors from the China Health National Survey 2000-2011 were assessed at baseline and in follow-up for 6- to 17-year-old children during 2000-2011 using mixed models. There was a large discrepancy between children's actual weight status (overweight: 16...
October 21, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29061024/-comparison-of-laparoscopic-distal-pancreatectomy-and-open-distal-pancreatectomy-in-pancreatic-ductal-adenocarcinoma
#18
K Xu, J J Su, M Su, L Yan, J Feng, X L Xin, Y L Chen
Objective: To compare and evaluate the curative effect of laparoscopic distal pancreatectomy(LDP) and traditional open distal pancreatectomy(ODP) in pancreatic ductal adenocarcinoma. Methods: The clinical data of 15 patients treated by LDP and 87 contemporaneous cases treated by ODP from January 2010 to November 2015 was collected, and the curative effect and prognosis of these patients were retrospectively analyzed. Results: The operation time of LDP group was (286.5±48.1) min, significantly longer than that of OPD group(226...
October 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29059510/glucose-response-to-exercise-in-the-post-prandial-period-is-independent-of-exercise-intensity
#19
P Shambrook, M I Kingsley, D W Wundersitz, P D Xanthos, V L Wyckelsma, B A Gordon
This study investigated the acute glucose response to low-intensity, moderate-intensity, and high-intensity interval exercise compared to no-exercise in healthy insufficiently active males using a four-arm, randomised, crossover design. Ten males (age: 37.3±7.3 years, BMI: 29.3±6.5 kg·m(-2) ) completed four 30 minute interventions at weekly intervals comprising low-intensity exercise (LIE) at ~35% VO2 R, moderate-intensity exercise (MIE) at ~50% VO2 R, high-intensity interval exercise (HIIE) at ~80% VO2 R, and a no-exercise control...
October 23, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29053869/enzymatic-hydrolysis-of-fumonisins-in-the-gastrointestinal-tract-of-broiler-chickens
#20
B Grenier, H E Schwartz-Zimmermann, C Gruber-Dorninger, I Dohnal, M Aleschko, G Schatzmayr, W D Moll, T J Applegate
Fumonisins (FB) are among the most frequently detected mycotoxins in feedstuffs and finished feed, and recent data suggest that the functions of the gastrointestinal tract (GIT) in poultry species might be compromised at doses ranging from 10 to 20 mg/kg, close to field incidences and below the US and EU guidelines. Strategies are therefore necessary to reduce the exposure of poultry to FB. In the present study, we assessed the efficacy of fumonisin esterase FumD (EC 3.1.1.87, commercial name FUMzyme®) to cleave the tricarballylic acid side chains of FB, leading to the formation of non-toxic hydrolyzed fumonisins in the GIT of broiler chickens...
October 5, 2017: Poultry Science
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