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https://www.readbyqxmd.com/read/27908182/prostate-deformation-from-inflatable-rectal-probe-cover-and-dosimetric-effects-in-prostate-seed-implant-brachytherapy
#1
Jun Lian, Yeqin Shao, Larry D Potter, Ronald C Chen, Jordan A Holmes, Eleanor A Pryser, Jie Shen, Dinggang Shen, Andrew Z Wang
PURPOSE: Prostate brachytherapy is an important treatment technique for patients with localized prostate cancer. An inflatable rectal ultrasound probe cover is frequently utilized during the procedure to adjust for unfavorable prostate position relative to the implant grid. However, the inflated cover causes prostate deformation, which is not accounted for during dosimetric planning. Most of the therapeutic dose is delivered after the procedure when the prostate and surrounding organs-at-risk are less deformed...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27907976/are-complications-of-stress-urinary-incontinence-surgery-procedures-associated-with-the-position-of-the-sling
#2
Jacek Kociszewski, George Fabian, Susanne Grothey, Andrzej Kuszka, Aneta Zwierzchowska, Wojciech Majkusiak, Ewa Barcz
OBJECTIVES: To evaluate whether the sling position is associated with particular types of complications in patients undergoing suburethral sling placement for stress urinary incontinence. METHODS: Data from 100 women diagnosed at the Evangelical Hospital Hagen-Haspe with complications after suburethral sling insertion were analyzed. All patients underwent pelvic floor ultrasound to assess: urethral length, sling location in relation to the urethral length (%) and the sling distance to the longitudinal smooth muscle complex of the urethra (the sling-longitudinal smooth muscle distance)...
December 1, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/27904451/the-ratio-of-weight-loss-to-planning-target-volume-significantly-impacts-setup-errors-in-nasopharyngeal-cancer-patients-undergoing-helical-tomotherapy-with-daily-megavoltage-computed-tomography
#3
Wei-Hsien Hou, Chun-Wei Wang, Chiao-Ling Tsai, Feng-Ming Hsu, Jason Chia-Hsien Cheng
BACKGROUND: Changes in head and neck anatomy during radiation therapy (RT) produce setup uncertainties of nasopharyngeal cancer (NPC) irradiation. We retrospectively analyzed image guidance data to identify clinical predictors of setup errors. PATIENTS AND METHODS: The data of 217 NPC patients undergoing definitive RT on a helical tomotherapy (HT) unit were analyzed. Factors including tumor stage, body mass index, weight loss, and planning target volume (PTV) were assessed as predictors of daily megavoltage computed tomography (MVCT) setup displacements, which were automatically registered using software...
December 1, 2016: Radiology and Oncology
https://www.readbyqxmd.com/read/27903330/intraindividual-cognitive-variability-in-middle-age-predicts-cognitive-impairment-8-10-years-later-results-from-the-wisconsin-registry-for-alzheimer-s-prevention
#4
Rebecca L Koscik, Sara E Berman, Lindsay R Clark, Kimberly D Mueller, Ozioma C Okonkwo, Carey E Gleason, Bruce P Hermann, Mark A Sager, Sterling C Johnson
OBJECTIVES: Intraindividual cognitive variability (IICV) has been shown to differentiate between groups with normal cognition, mild cognitive impairment (MCI), and dementia. This study examined whether baseline IICV predicted subsequent mild to moderate cognitive impairment in a cognitively normal baseline sample. METHODS: Participants with 4 waves of cognitive assessment were drawn from the Wisconsin Registry for Alzheimer's Prevention (WRAP; n=684; 53.6(6.6) baseline age; 9...
November 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27893769/assessing-visual-fields-in-patients-with-retinitis-pigmentosa-using-a-novel-microperimeter-with-eye-tracking-the-mp-3
#5
Nozomi Igarashi, Masato Matsuura, Yohei Hashimoto, Kazunori Hirasawa, Hiroshi Murata, Tatsuya Inoue, Obata Ryo, Makoto Aihara, Ryo Asaoka
PURPOSE: The purpose of the current study is to investigate the test-retest reproducibility of visual fields (VFs) measured with the MP-3 microperimeter, in patients with retinitis pigmentosa (RP). METHOD: VFs were twice measured with the MP-3 and also the Humphrey Field Analyzer, using the 10-2 test grid pattern in both perimeters, in 30 eyes (15 right and 15 left eyes) of 18 RP patients (11 males and 7 females). Test-retest reproducibility was assessed using the mean absolute deviation (MAD) measure at all 68 points in the test grid...
2016: PloS One
https://www.readbyqxmd.com/read/27892671/association-between-the-xrcc3-thr241met-polymorphism-and-gastrointestinal-cancer-risk-a-meta-analysis
#6
Mohammad Hossein Sahami-Fard, Ali Reza Mousa Mayali, Ahmad Tajehmiri
Background: The x-ray repair cross-complementing group 3 (XRCC3) encodes a protein involved in the homologous recombination repair (HRR) pathway for double-strand DNA repair. Associations of the XRCC3 Thr241Met polymorphism with various cancers have been widely reported. However, published data on links between XRCC3 Thr241Met and gastrointestinal (GI) cancer risk are inconsistent. Objective and Methods: A meta-analysis was conducted to characterize the relationship between XRCC3 Thr241Met polymorphisms and GI cancer risk...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27886446/mean-platelet-volume-as-a-marker-for-differentiating-disease-flare-from-infection-in-beh%C3%A3-et-s-disease
#7
Hee Jung Ryu, Mi Ryoung Seo, Hyo Jin Choi, Kwang-Pil Ko, Pil Whan Park, Han Joo Baek
AIM: The aim of this study was to investigate the association between mean platelet volume (MPV) and clinical manifestations, disease activity or infection in patients with Behçet's disease (BD). METHODS: In total, 193 patients diagnosed with BD according to the international criteria for BD were enrolled. Demographic data, clinical manifestations and laboratory results were collected by medical interviews and reviewing medical records. RESULTS: The female : male ratio was 2 : 1 and the age of symptom onset was 32...
November 25, 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/27884318/n-acetylcysteine-ameliorates-liver-injury-in-a-rat-model-of-intestinal-ischemia-reperfusion
#8
Konstantinos Kalimeris, Panagiotis Briassoulis, Agathi Ntzouvani, Tzortzis Nomikos, Kleio Papaparaskeva, Aikaterini Politi, Chrysanthi Batistaki, Georgia Kostopanagiotou
BACKGROUND: N-acetylcysteine (NAC) is an antioxidant with direct and indirect antioxidant actions used in the clinical setting. Oxidative stress is known to play a pivotal role in the intestinal ischemia reperfusion (IIR). Therefore, we studied the effect of different pretreatment regimens with NAC on the IIR injury in rats. MATERIALS AND METHODS: Thirty-five male Wistar rats were randomly assigned to five groups. In group sham, only laparotomy was performed. Group control underwent IIR without NAC...
December 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27878751/assessment-of-the-relationship-between-serum-paraoxonase-activity-and-epicardial-adipose-tissue-in-hemodialysis-patients
#9
Emad Abdallah, Samya El-Shishtawy, Nevine Sherif, Ahmed Ali, Omnia El-Bendary
PURPOSE: Paraoxonase-1 (PON-1) is a high-density lipoprotein-associated (HDL) enzyme, which has been shown to reduce susceptibility to low-density lipoprotein (LDL) peroxidation. Epicardial adipose tissue (EAT) is a marker of atherosclerosis. The aim of this study was to determine the relationship between PON-1 activity and EAT in hemodialysis (HD) patients. METHODS: This is a cross-sectional study conducted on 72 (43 males) HD patients with end-stage renal disease...
November 23, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27876736/-the-speech-audiometry-using-the-matrix-sentence-test
#10
M Yu Boboshko, E V Zhilinskaya, A Vazhybok, N V Mal'tseva, M Tsokol', B Kol'meier
The matrix sentence test in which the five-word semantically unpredictable sentences presented under the background noise conditions are used as the speech material was designed and validated for many languages. The objective of the present study was to evaluate the Russian version of the matrix sentence test (RuMatrix test) in the listeners of different ages with normal hearing. At the first stage of the study, 35 listeners at the age from 18 to 33 year were examined. The results of the estimation of the training effect dictated the necessity of conducting two training tracks before carrying out the RuMatrix test proper...
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27871837/modifying-the-risk-of-recurrent-preterm-birth-influence-of-trimester-specific-changes-in-smoking-behaviors
#11
Jessica L Wallace, Kristen L Aland, Kate Blatt, Elizabeth Moore, Emily A DeFranco
BACKGROUND: Women with at least 1 prior occurrence of premature birth often have demographic and medical risk factors that are not modifiable. However, smoking cessation could be a targeted intervention in which a woman with a history of premature birth may be able to reduce her future risk of recurrence. OBJECTIVE: This study aims to assess how trimester-specific smoking patterns influence the risk of recurrent premature birth. STUDY DESIGN: This was a population-based retrospective cohort study of singleton nonanomalous live births in Ohio, 2006-2012 using vital statistics birth records...
November 18, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27864725/endoscope-assisted-extracapsular-dissection-of-benign-parotid-tumors-through-a-single-cephaloauricular-furrow-incision-versus-a-conventional-approach
#12
Song Fan, Guo-Kai Pan, Wei-Liang Chen, Zhao-Yu Lin, Fa-Ya Liang, Qun-Xing Li, Da-Ming Zhang, You-Yuan Wang, Han-Qing Zhang, Wei-Xiong Chen, Rui Chen, Xiao-Ming Huang, Jian-Tao Ye, Jin-Song Li
BACKGROUND: A few modified approaches have been reported for performing endoscope-assisted dissections of benign parotid tumors, but none that use incisions totally hidden in a natural furrow. This study evaluated the feasibility of performing endoscope-assisted extracapsular dissections of benign parotid tumors using a single cephaloauricular furrow incision. METHODS: Forty-six patients with benign parotid superficial lobe tumors were randomly divided into two groups: an endoscope-assisted (21 patients) group or a conventional (25 patients) surgery group...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27863845/macular-atrophy-in-neovascular-age-related-macular-degeneration-with-monthly-versus-treat-and-extend-ranibizumab-findings-from-the-trex-amd-trial
#13
Nizar S Abdelfattah, Mayss Al-Sheikh, Sean Pitetta, Ahmed Mousa, SriniVas R Sadda, Charles C Wykoff
PURPOSE: To compare the enlargement rate of macular atrophy (ERMA) in eyes treated with ranibizumab monthly or using a treat-and-extend (TREX) regimen for neovascular age-related macular degeneration (AMD) or fellow control eyes, as well as analyze risk factors for macular atrophy (MA) development and progression. DESIGN: Eighteen-month, multicenter, randomized, controlled clinical trial. PARTICIPANTS: Sixty patients with treatment-naïve neovascular AMD in 1 eye randomized 1:2 to monthly or TREX ranibizumab...
November 15, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27863792/presence-of-latent-myofascial-trigger-points-and-determination-of-pressure-pain-thresholds-of-the-shoulder-girdle-in-healthy-children-and-young-adults-a-cross-sectional-study
#14
Luciane S Sacramento, Paula R Camargo, Aristides L Siqueira-Júnior, Jean P Ferreira, Tania F Salvini, Francisco Alburquerque-Sendín
OBJECTIVE: The primary objective of this study was to compare the number of myofascial trigger points (MTPs) and the pressure pain thresholds (PPTs) in the shoulder girdle, on the dominant and nondominant sides, between healthy children and adults. The secondary aim was to assess the correlations between the number of MTPs and the PPTs in these populations. METHODS: A cross-sectional study was performed. Thirty-five children (aged 9.1 ± 1.7 years) and 35 adults (aged 23...
November 15, 2016: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/27861889/margatoxin-bound-quantum-dots-as-a-novel-inhibitor-of-the-voltage-gated-ion-channel-kv1-3
#15
Austin B Schwartz, Anshika Kapur, Wentao Wang, Zhenbo Huang, Erminia Fardone, Goutam Palui, Hedi Mattoussi, Debra Ann Fadool
Venom-derived ion channel inhibitors have strong channel selectivity, potency, and stability; however, tracking delivery to their target can be challenging. Herein, we utilized luminescent quantum dots (QDs) conjugated to margatoxin (MgTx) as a traceable vehicle to target a voltage-dependent potassium channel, Kv1.3, which has a select distribution and well characterized role in immunity, glucose metabolism, and sensory ability. We screened both unconjugated (MgTx) and conjugated MgTx (QD-MgTx) for their ability to inhibit Shaker channels Kv1...
November 8, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27861261/lung-recruitment-improves-right-ventricular-performance-after-cardiopulmonary-bypass-a-randomised-controlled-trial
#16
Silvina Longo, Juan Siri, Cecilia Acosta, Alberto Palencia, Arturo Echegaray, Iván Chiotti, Andrés Parisi, Lila Ricci, Marcela Natal, Fernando Suarez-Sipmann, Gerardo Tusman
BACKGROUND: Atelectasis after cardiopulmonary bypass (CPB) can affect right ventricular (RV) performance by increasing its outflow impedance. OBJECTIVE: The aim of this study was to determine whether a lung recruitment manoeuvre improves RV function by re-aerating the lung after CPB. DESIGN: Randomised controlled study. SETTING: Single-institution study, community hospital, Córdoba, Argentina. PATIENTS: Forty anaesthetised patients with New York Heart Association class I or II, preoperative left ventricular ejection fraction at least 50% and Euroscore 6 or less scheduled for cardiac surgery with CPB...
November 16, 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27859746/a-prospective-randomized-masked-placebo-controlled-clinical-study-of-capromorelin-in-dogs-with-reduced-appetite
#17
B Zollers, J A Wofford, E Heinen, M Huebner, L Rhodes
BACKGROUND: Reduced appetite is a common clinical sign in dogs. This study evaluated the effectiveness and safety of capromorelin oral solution, (ENTYCE(®) , Aratana Therapeutics, Leawood, KS) a new drug that is a ghrelin receptor agonist, for stimulation of appetite in dogs with reduced appetite. HYPOTHESIS/OBJECTIVES: Capromorelin will increase appetite, as measured by the owner's evaluation, over 4 days. An additional objective was to evaluate the safety of capromorelin at the labeled dose...
November 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27856801/efficacy-of-triamcinolone-acetate-and-methylprednisolone-acetonide-for-intrabursal-injection-after-ultrasound-guided-percutaneous-treatment-in-painful-shoulder-calcific-tendonitis-a-randomized-controlled-trial
#18
Milva Battaglia, Federica Guaraldi, Davide Gori, Emanuela Castiello, Emanuela Arvat, Alessandra Sudanese
BACKGROUND: Ultrasound-guided percutaneous irrigation of calcific tendinopathy (US-PICT) with intrabursal steroid injection is an elective treatment for painful rotator cuff calcific tendinopathy. PURPOSE: To compare the efficacy of post-US-PICT intrabursal 40 mg injection of triamcinolone acetonide (TA) versus methylprednisolone acetate (MA). MATERIAL AND METHODS: Forty patients (22 women; mean age 48.7 ± 7.2 years) with painful shoulder calcific tendinopathy, treated with TA or MA injected intrabursally after US-PICT, were included in this randomized controlled trial...
November 17, 2016: Acta Radiologica
https://www.readbyqxmd.com/read/27844413/relationship-between-circulating-anti-thyroglobulin-antibodies-tgab-and-tumor-metabolism-in-patients-with-differentiated-thyroid-cancer-dtc-prognostic-implications
#19
S Morbelli, G Ferrarazzo, E Pomposelli, F Pupo, G Pesce, I Calamia, F Fiz, A Clapasson, M Bauckneht, M Minuto, G Sambuceti, M Giusti, M Bagnasco
PURPOSE: TgAb have been proposed as tumor markers in DTC. Recent evidence links TgAb levels with DTC aggressiveness. We aimed to evaluate the relationship between TgAb and tumor glucose metabolism in DTC patients. METHODS: Seventy-one DTC patients who underwent (18)F-FDG PET/CT were included. According to TgAb value and trends, patients were divided into TgAb positive (TgAb+) or negative (TgAb-) as well as in patients with increasing (Inc-TgAb) or decreasing (Dec-TgAb) trend...
November 14, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27827311/comparative-effectiveness-of-second-line-agents-for-the-treatment-of-diabetes-type-2-in-preventing-kidney-function-decline
#20
Adriana M Hung, Christianne L Roumie, Robert A Greevy, Carlos G Grijalva, Xulei Liu, Harvey J Murff, T Alp Ikizler, Marie R Griffin
BACKGROUND AND OBJECTIVES: Diabetes is the leading cause of ESRD. Glucose control improves kidney outcomes. Most patients eventually require treatment intensification with second-line medications; however, the differential effects of those therapies on kidney function are unknown. DESIGN, SETTING, PARTICIPANTS & MEASUREMENTS: We studied a retrospective cohort of veterans on metformin monotherapy from 2001 to 2008 who added either insulin or sulfonylurea and were followed through September of 2011...
November 8, 2016: Clinical Journal of the American Society of Nephrology: CJASN
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