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https://www.readbyqxmd.com/read/29779290/-maxillary-first-premolar-with-four-canals-a-case-report
#1
Yang Meng, De-Gang Sun
This article presented a case of discovering and diagnosing three roots with four canals of the maxillary first premolar. We found and located the extra root canal by clinical diagnosis, careful observation during the operation, and multiangle X-ray. We further confirmed the existence of the three roots with four canals with the help of cone-beam computed tomography. Finally, we verified the success of the high-quality root-canal therapy through root optical microscopy.
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29778474/a-longitudinal-observational-study-of-the-dynamics-of-mycoplasma-bovis-antibodies-in-naturally-exposed-and-diseased-dairy-cows
#2
Mette B Petersen, Jeanette Pedersen, Dinah L Holm, Matthew Denwood, Liza R Nielsen
Mycoplasma bovis is an important pathogen causing disease and substantial economic losses in cattle. However, knowledge of the dynamics of antibody responses in individual cows in the face of an outbreak is currently extremely limited. The use of commercial antibody tests to support clinical decision-making and for surveillance purposes is therefore challenging. Our objective was to describe the dynamics of M. bovis antibody responses in 4 Danish dairy herds experiencing an acute outbreak of M. bovis-associated disease, and to compare the antibody dynamics between dairy cows with different disease manifestations...
May 16, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29777580/context-encoding-enables-machine-learning-based-quantitative-photoacoustics
#3
Thomas Kirchner, Janek Gröhl, Lena Maier-Hein
Real-time monitoring of functional tissue parameters, such as local blood oxygenation, based on optical imaging could provide groundbreaking advances in the diagnosis and interventional therapy of various diseases. Although photoacoustic (PA) imaging is a modality with great potential to measure optical absorption deep inside tissue, quantification of the measurements remains a major challenge. We introduce the first machine learning-based approach to quantitative PA imaging (qPAI), which relies on learning the fluence in a voxel to deduce the corresponding optical absorption...
May 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29774418/prevalence-of-glaucoma-in-germany-results-from-the-gutenberg-health-study
#4
René Höhn, Stefan Nickels, Alexander K Schuster, Philipp S Wild, Thomas Münzel, Karl J Lackner, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer
PURPOSE: To determine the prevalence of glaucoma according to the International Society for Geographical and Epidemiological Ophthalmology (ISGEO) classification in an adult German cohort. METHODS: The Gutenberg Health Study is a population-based, prospective cohort study in the Rhine-Main Region in mid-western Germany with a total of 15,010 participants. In this study, the first 5000 subjects with an age range between 35 and 74 years were included. Optic disk pictures were obtained by a non-mydriatic fundus camera (Visucam™) and analyzed using the Visupac™ software...
May 17, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29774372/-optical-coherence-tomography-for-skin-pathologies
#5
REVIEW
J Welzel, S Schuh
Optical coherence tomography (OCT) has become established in routine diagnosis in dermatology only in the last few years. The reason is that the skin is a challenge for OCT as a strong scattering medium, because only a very small proportion of photons is reflected and can be used for imaging. In addition, in most cases a visual assessment or a biopsy is sufficient. Nevertheless, the main field of application in dermatology is the diagnostics of epithelial skin tumors. The OCT is suitable for the early recognition of small, clinically and light microscopically unspecific basal cell carcinomas as well as for the differential diagnosis of other tumors and precancerous lesions...
May 17, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29774297/parasitic-and-zoonotic-meningoencephalitis-in-humans-and-equids-current-knowledge-and-the-role-of-halicephalobus-gingivalis
#6
REVIEW
ThankGod E Onyiche, Theresa O Okute, Oluwasina S Oseni, Dennis O Okoro, Abdullahi A Biu, Albert W Mbaya
Halicephalobus gingivalis is a saprophytic nematode parasite that causes a rare form of fatal meningoencephalomyelitis in equids, humans, and ruminants. This nematode has neurotropic activity, but has also been found in the kidney, liver, lungs, optic nerves and even heart of its host. Despite the zoonotic potential and severity of the disease, the epidemiology, pathogenesis, life cycle, and risk factors are poorly understood. Cases have been reported from several countries in Europe countries and North America but none is recorded in Africa except Egypt...
February 2018: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29772589/-optical-care-in-low-vision-patients
#7
Bettina von Livonius
The numbers of low vision patients will steadily increase because of increasing longevity. It is important to be aware of those patients so that visual rehabilitation can be started as soon as possible and needed. Before the adjustment of low vision devices a diagnosis should be confirmed in order to check any therapeutic option and to ensure the best individual rehabilitation. If there is no further therapeutic option left a detailed anamnesis of the problems due to low vision should be made to ensure that every patient gets the optical or electronic device he really needs in his everyday life...
May 17, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29772040/oct-angiography-helps-distinguish-between-proliferative-macular-telangiectasia-type-2-and-neovascular-age-related-macular-degeneration
#8
Fang Zheng, Elie H Motulsky, João Rafael de Oliveira Dias, Edith Pérez de López, Giovanni Gregori, Philip J Rosenfeld
BACKGROUND AND OBJECTIVE: To demonstrate the advantage of optical coherence tomography angiography (OCTA) for the diagnosis and management of proliferative macular telangiectasia type 2 (MacTel2) masquerading as neovascular age-related macular degeneration (AMD). PATIENTS AND METHODS: This is an observational cases series. Three patients referred with the diagnosis of neovascular AMD were identified in this retrospective study. In addition to color fundus, fluorescein angiography, and spectral-domain OCT (SD-OCT) imaging, SD-OCTA (AngioPlex; Carl Zeiss Meditec, Dublin, CA) was performed...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29768508/i-scan-optical-enhancement-for-the-in-vivo-prediction-of-diminutive-colorectal-polyp-histology-results-from-a-prospective-three-phased-multicentre-trial
#9
Entcho Klenske, Steffen Zopf, Clemens Neufert, Andreas Nägel, Jürgen Siebler, Jürgen Gschossmann, Steffen Mühldorfer, Lukas Pfeifer, Sarah Fischer, Francesco Vitali, Marietta Iacucci, Subrata Ghosh, Michelle G Rath, Peter Klare, Gian E Tontini, Markus F Neurath, Timo Rath
BACKGROUND AND AIMS: Dye-less chromoendoscopy is an emerging technology for colorectal polyp characterization. Herein, we investigated whether the newly introduced I-scan optical enhancement (OE) can accurately predict polyp histology in vivo in real-time. METHODS: In this prospective three-phased study, 84 patients with 230 diminutive colorectal polyps were included. During the first two study phases, five endoscopists assessed whether analysis of polyp colour, surface and vascular pattern under i-scan OE can differentiate in vivo between adenomatous and hyperplastic polyps...
2018: PloS One
https://www.readbyqxmd.com/read/29766684/neuromyelitis-optica-review-and-utility-of-testing-aquaporin-4-antibody-in-typical-optic-neuritis
#10
Meagan Seay, Janet C Rucker
Neuromyelitis optica (NMO) is an autoimmune, inflammatory demyelinating disorder often leading to severe vision impairment and disability. The discovery of a diagnostic biomarker, the aquaporin-4 antibody (AQP4-IgG), transformed the clinical diagnosis and treatment of NMO and broadened the spectrum of disease [NMO spectrum disorders (NMOSD)]. Though the antibody is highly sensitive and specific to NMOSD, routine testing in patients with typical optic neuritis is considered controversial. This article will provide a brief review of NMOSD and highlight the pros and cons of routine testing in typical optic neuritis...
May 16, 2018: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29766541/gold-nanoparticles-in-ophthalmology
#11
REVIEW
Florence Masse, Mathieu Ouellette, Guillaume Lamoureux, Elodie Boisselier
Many research projects are underway to improve the diagnosis and therapy in ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and different strategies are being developed to strengthen patient care. One of these strategies is the use of gold nanoparticles (GNP) for their multiple properties and their ability to be used as both diagnosis and therapy tools. This review exhaustively details research developing GNPs for use in ophthalmology. The toxicity of GNPs and their distribution in the eye are described through in vitro and in vivo studies...
May 16, 2018: Medicinal Research Reviews
https://www.readbyqxmd.com/read/29765954/an-unusual-presentation-of-esthesioneuroblastoma-in-a-young-pregnant-female
#12
Meenakshi Wadhwani, Amar Ranjan, Kulbhushan Gangwani, Prasenjit Das
Background: Esthesioneuroblastoma is a rare neuroepithelial tumor arising from the olfactory epithelium in the cribriform plate or nasal cavity. It accounts for 1-5% of cases of malignant neoplasms of the nasal cavity. Methods: A 20-year-old pregnant female presented with painful loss of vision in both eyes, on imaging diagnosed as meningioma. There was a progressive increase in pain along with diminution of vision to the extent of complete loss of vision in the right eye...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29765647/controlled-fluorescence-quenching-by-antibody-conjugated-graphene-oxide-to-measure-tau-protein
#13
Ao Huang, Luning Zhang, Weiwei Li, Zeyu Ma, Shi Shuo, Tianming Yao
We report an ultrasensitive immunoassay for tau protein-a key marker of Alzheimer's disease. This sensing platform relies on graphene oxide (GO) surfaces conjugated with anti-human tau antibody to provide quantitative binding sites for the tau protein. The GO quenches standard fluorescein isothiocyanate labelled tau (tau-FITC) when tau protein and tau-FITC are both present and compete for the binding sites. This change in fluorescence signal can be used to quantitate tau protein. In contrast with traditional enzyme-linked immunosorbent assay (ELISA), our method does not require enzyme-linked secondary antibodies for protein recognition nor does it require an enzyme substrate for optical signal generation...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29763544/multi-fluorophore-dna-origami-beacon-as-a-biosensing-platform
#14
Denis Selnihhin, Steffen Møller Sparvath, Søren Preus, Victoria Birkedal, Ebbe Sloth Andersen
Biosensors play increasingly important roles in many fields, from clinical diagnosis to environmental monitoring, and there is a growing need for cheap and simple analytical devices. DNA nanotechnology provides methods for the creation of sophisticated biosensors, however many of the developed DNA-based sensors are limited by cumbersome and time-consuming readouts involving advanced experimental techniques. Here we describe design, construction and characterization of an optical DNA origami nano-biosensor device exploiting arrays of precisely positioned organic fluorophores...
May 15, 2018: ACS Nano
https://www.readbyqxmd.com/read/29763511/a-review-of-non-invasive-imaging-in-extramammary-paget-s-disease
#15
REVIEW
Claire-Audrey Y Bayan, Trisha Khanna, Veronica Rotemberg, Faramarz H Samie, Nathalie C Zeitouni
Extramammary Paget's Disease (EMPD) is a rare intraepithelial adenocarcinoma that classically manifests with pruritic, erythematous, scaling plaques. The clinical picture frequently mimics inflammatory or infectious conditions, and is thus commonly misdiagnosed. The assessment of tumor margins is equally challenging as tumors have a propensity to spread beyond clinically visible boundaries. Appropriate non-invasive diagnostic tools can assist in the early detection, diagnosis, and management of EMPD. This paper will review the literature on non-invasive imaging modalities used in EMPD...
May 15, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29761981/-plaque-segmentation-of-intracoronary-optical-coherence-tomography-images-based-on-k-means-and-improved-random-walk-algorithm
#16
Guanglei Wang, Pengyu Wang, Yechen Han, Xiuling Liu, Yan Li, Qian Lu
In recent years, optical coherence tomography (OCT) has developed into a popular coronary imaging technology at home and abroad. The segmentation of plaque regions in coronary OCT images has great significance for vulnerable plaque recognition and research. In this paper, a new algorithm based on K -means clustering and improved random walk is proposed and Semi-automated segmentation of calcified plaque, fibrotic plaque and lipid pool was achieved. And the weight function of random walk is improved. The distance between the edges of pixels in the image and the seed points is added to the definition of the weight function...
June 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29761698/assessment-of-compressive-raman-versus-hyperspectral-raman-for-microcalcification-chemical-imaging
#17
Camille Scotté, Hilton B de Aguiar, Didier Marguet, Ellen Marie Green, Pascaline Bouzy, Sébastien Vergnole, Charles Peter Winlove, Nicholas Stone, Herve Rigneault
We experimentally implement a compressive Raman technology (CRT) that incorporates chemometric analysis directly into the spectrometer hardware by means of a digital micromirror device (DMD). The DMD is a programmable optical filter on which optimized binary filters are displayed. The latter are generated with an algorithm based on the Cramer-Rao lower bound. We com-pared the developed CRT microspectrometer with two conventional state-of-the-art Raman hyperspectral imaging systems on samples mimicking microcalcifications relevant for breast cancer diagnosis...
May 15, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29760988/intra-class-variability-in-diffuse-reflectance-spectroscopy-application-to-porcine-adipose-tissue
#18
Félix Fanjul-Vélez, Laura Arévalo-Díaz, José L Arce-Diego
Optical diffuse reflectance spectroscopy (DRS) has great potential in the study, diagnosis, and discrimination of biological tissues. Discrimination is based on massive measurements that conform training sets. These sets are then used to classify tissues according to the biomedical application. Classification accuracy depends strongly on the training dataset, which typically comes from different samples of the same class, and from different points of the same sample. The variability of these measurements is not usually considered and is assumed to be purely random, although it could greatly influence the results...
May 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29760971/quantitative-characterization-of-turbidity-by-radiative-transfer-based-reflectance-imaging
#19
Peng Tian, Cheng Chen, Jiahong Jin, Heng Hong, Jun Q Lu, Xin-Hua Hu
A new and noncontact approach of multispectral reflectance imaging has been developed to inversely determine the absorption coefficient of μ a , the scattering coefficient of μs and the anisotropy factor g of a turbid target from one measured reflectance image. The incident beam was profiled with a diffuse reflectance standard for deriving both measured and calculated reflectance images. A GPU implemented Monte Carlo code was developed to determine the parameters with a conjugate gradient descent algorithm and the existence of unique solutions was shown...
May 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29757809/applicability-of-isnt-rule-using-bmo-mrw-to-differentiate-between-healthy-and-glaucomatous-eyes
#20
Do Young Park, Eun Jung Lee, Jong Chul Han, Changwon Kee
PURPOSE: We evaluated the applicability of the ISNT rule using Bruch's membrane opening minimum rim width (BMO-MRW) in healthy eyes and eyes with normal tension glaucoma (NTG). METHODS: 124 healthy eyes and 136 NTG eyes were analyzed. Using two-dimensional disc photographs, neuroretinal rim (NRR) thickness was measured at the superior, inferior, nasal, and temporal sides of the optic disc. Using spectral domain-optical coherence tomography (SD-OCT), BMO-MRW was measured at the same regions...
May 11, 2018: Journal of Glaucoma
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