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Adenoid cystic carcinoma of cervix

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https://www.readbyqxmd.com/read/26745061/is-immunohistochemical-sex-hormone-binding-globulin-expression-important-in-the-differential-diagnosis-of-adenocarcinomas
#1
Gulay Bulut, Mustafa Kosem, Mehmet Deniz Bulut, Remzi Erten, Irfan Bayram
Adenocarcinomas (AC) are the most frequently encountered carcinomas. It may be quite challenging to detect the primary origin when those carcinomas metastasize and the first finding is a metastatic tumor. This study evaluated the role of sex hormone binding globulin (SHBG) positivity in tumor cells in the subclassification and detection of the original organ of adenocarcinomas. Between 1994 and 2008, 64 sections of normal tissue belonging to ten organs, and 116 cases diagnosed as adenoid cystic carcinoma and mucoepidermoid carcinoma of the salivary gland, lung adenocarcinoma, invasive ductal carcinoma of the breast, adenocarcinoma of stomach, colon, gallbladder, pancreas and prostate, endometrial adenocarcinoma and serous adenocarcinoma and mucinous adenocarcinoma of the ovary, were sent to the laboratory at the Department of Pathology at the Yuzuncu Yil University School of Medicine, where they were stained immunohistochemically, using antibodies against SHBG...
2015: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/26285694/co-existing-of-adenoid-cystic-carcinoma-and-invasive-squamous-cell-carcinoma-of-the-uterine-cervix-a-report-of-3-cases-with-immunohistochemical-study-and-evaluation-of-human-papillomavirus-status
#2
Xiaohua Shi, Shafei Wu, Zhen Huo, Qing Ling, Yufeng Luo, Zhiyong Liang
BACKGROUNDS: The aim of this study was to describe the clinicopathological characteristics and high-risk human papillomavirus (HPV) infection status in patients diagnosed with co-existing of adenoid cystic carcinoma (ACC) and invasive squamous cell carcinoma (SCC) of the uterine cervix. METHODS: Three patients were identified from the pathology databank of Peking Union Medical College Hospital from year 2000 to 2014. Immunohistochemistry and in situ hybridization (ISH) were employed in this study...
2015: Diagnostic Pathology
https://www.readbyqxmd.com/read/26278519/comparison-of-cytologic-characteristics-between-adenoid-cystic-carcinoma-and-adenoid-basal-carcinoma-in-the-uterine-cervix
#3
Juhyeon Jeong, Seung Yeon Ha, Hyun Yee Cho, Dong Hae Chung, Jungsuk An
BACKGROUND: Adenoid cystic carcinoma (ACC) and adenoid basal carcinoma (ABC) are rare in the uterine cervix. ACC is more aggressive than ABC, thus accurate differential diagnosis is important. In this study, we identified cytologic features useful in distinguishing these two tumors for diagnosis. METHODS: Three cases of ACC and five cases of ABC were selected for this study. Cervicovaginal smear slides were reviewed retrospectively, and the area, circumference, major axis, and minor axis of nuclei were measured using an image analyzer...
September 2015: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/26090035/adenoid-cystic-carcinoma-of-cervix-two-cases-report-and-review-of-the-literature
#4
REVIEW
Khadija Benhayoune, Hinde El Fatemi, Abdelaziz Bannani, Abdelilah Melhouf, Toufik Harmouch
Adenoid cystic carcinoma of the cervix is a rare and aggressive tumor with fatal outcome. In this paper we report two cases of primary adenoid cystic carcinoma and a review of literature. A 80 years old woman, admitted to our hospital with postmenopausal bleeding and hydrorrhea. Gynealogical examination showed a cervical stenotic with the presence of a tumor processus. Biopsy of cervical growth was done. 80-year-old woman presented with vaginal bleeding with pelvic pain. Physical examination revealed a friable mass in the cervix...
2015: Pan African Medical Journal
https://www.readbyqxmd.com/read/25722772/adenoid-cystic-carcinoma-of-cervix-in-younger-women-report-of-two-new-cases
#5
Mohamed Sinaa, Mohamed Oukabli, Abderahmane Albouzidi
Adenoid cystic carcinoma is a malignant epithelial neoplasm derived from the salivary glands. Primary adenoid cystic carcinoma of the cervix is extremely rare, accounting for less than 1% of all cervical carcinomas. Its origin is debatable. It generally presents in elderly age group, however only twenty three cases have been reported in women less than age 45 years old. In this paper we report two new cases of primary adenoid cystic carcinoma in younger women and include the cytopathology and histopathology findings...
2014: Pan African Medical Journal
https://www.readbyqxmd.com/read/25607411/adenoid-basal-carcinoma-like-tumor-combined-with-invasive-squamous-cell-carcinoma-foci-of-uterine-cervix-a-case-report-of-55-year-old-woman-with-literature-review
#6
Andrzej Wincewicz, Piotr Lewitowicz, Sławka Urbaniak-Wąsik, Luiza Kanczuga-Koda, Mariusz Koda, Olga Adamczyk-Gruszka, Stanisław Sulkowski
BACKGROUND: Adenoid basal carcinoma (ABC) of uterine cervix is an extraordinary example of carcinoma with both basal and glandular cell types. Here we present such a case of ABC combined with invasive squamous cell carcinoma (SCC) of 55-year-old woman. METHODS: The tumor was stained with Hematoxylin-Eosin (HE), Mucicarmine, PAS/Alcian Blue, CK AE1/AE3, CK7, CD117 and Ki67. RESULTS: The whitish-grey 1 cm in-depth infiltration of endocervix was composed of infiltrative coalescing areas of CK AE1/AE3 positive carcinoma with peripheral palisading of basal cell type with spaces lined by Mucicarmine- and Alcian Blue-positive benign looking, glandular epithelium...
2014: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/25371884/a-case-of-adenoid-basal-carcinoma-of-the-uterine-cervix
#7
Hwi-Gon Kim, Yong Jung Song, Yong Jin Na, Ook-Hwan Choi
Adenoid basal carcinoma of the uterine cervix is uncommon neoplasia mostly occurring in postmenopausal women. It has excellent prognosis and a favorable clinical course. In addition, adenoid basal carcinoma is differentiated from adenoid cystic carcinoma by histologic and cellular morphologies, and immunohistochemistry. In this paper, we present the case of a 22 year old Korean female. She initially had a high-grade squamous intraepithelial lesion (HSIL) on Pap smear and a subsequent cervical loop electrosurgical excision procedure (LEEP) specimen revealing adenoid basal carcinoma...
December 2013: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/25361940/co-existing-adenoid-cystic-carcinoma-and-invasive-squamous-cell-carcinoma-of-the-uterine-cervix-a-rare-case-report-and-literature-review
#8
Xiaohua Shi, Xiaoyan Chang, Huanwen Wu, Xinyu Ren, Tonghua Liu, Marilyn M Bui
Adenoid cystic carcinoma (ACC) is a rare cervical malignancy, and its coexistence with other malignancies in the uterine cervix is extremely rare. Here, we present a case of coexistence of ACC and invasive squamous cell carcinoma (SCC) of the uterine cervix, as well as a literature review. A 68-year-old Chinese woman with vaginal bleeding underwent a cervical cytology screening, cervical biopsy, and finally cervical conization. Subsequent pathological diagnoses of coexisting ACC and invasive SCC were rendered with a positive margin...
2014: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/25207054/cervical-adenoid-basal-carcinoma-a-case-report
#9
Asuman Argon, Alper Sener, Osman Zekioğlu, Coşan Terek, Necmettin Ozdemir
Adenoid basal carcinoma (ABC) is a rare epithelial tumor of the cervix. It makes up approximately 1% of all cervical adenocarcinomas. Rare cases have been associated with common cervical epithelial tumors. We present a case of ABC associated with typical squamous cell carcinoma. A 54-year-old post-menopausal woman underwent D&C for vaginal bleeding. Histologically, the tumor was characterized by small cells with a narrow cytoplasm, making up islands and cords. Peripheral palissading in the cells surrounding the cystic areas that contained central cellular debris and keratin was noted...
December 2012: Balkan Medical Journal
https://www.readbyqxmd.com/read/24392415/adenoid-cystic-carcinoma-of-cervix-treatment-strategy
#10
Paramjeet Kaur, Anil Khurana, Ashok K Chauhan, Gajender Singh, Sant Parkash Kataria, Sunita Singh
Adenoid Cystic Carcinoma (ACC) of cervix behaves aggressively and it has a propensity for local infiltration, invasion in lymphatic vessels as well as perineural spaces, with subsequent haematogenous spread. In advanced disease (Stage III and IV), outcome is invariably poor. Moreover, these cases have a high tendency to recur locally and also to metastasize to distant sites. There are no standard treatment protocols because of rarity of disease. The guidelines for its management are established similarly as for staged squamous cell carcinoma of cervix...
November 2013: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/24075382/coexistent-squamous-cell-carcinoma-and-adenoid-basal-carcinoma-in-the-uterine-cervix-and-infection-with-human-papillomavirus-hpv-31
#11
Yu-Chieh Lin, Cherng-Lih Perng, Yi-Ming Chang, Yao-Feng Li, Yuan-Ming Tsai, Gwo-Jang Wu, Chih-Kung Lin
OBJECTIVE: Adenoid basal carcinoma (ABC) is an uncommon neoplasm of the uterine cervix. ABC can be accompanied by carcinoma in situ or invasive carcinoma. Most cases are discovered accidentally during radical hysterectomy. ABC is associated with a high risk of human papillomavirus infection (HPV), most often HPV 16 infection. CASE REPORT: We present a rare case of an 86-year-old Taiwanese married woman who suffered from bloody vaginal discharge and occasional lower abdominal pain and received cervical biopsy...
September 2013: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/22809729/adenoid-basal-hyperplasia-of-the-uterine-cervix-a-lesion-of-reserve-cell-type-distinct-from-adenoid-basal-carcinoma
#12
Olivier Kerdraon, Aurélie Cornélius, Marie-Odile Farine, Loïc Boulanger, Agnès Wacrenier
Adenoid basal hyperplasia is an underrecognized cervical lesion, resembling adenoid basal carcinoma, except the absence of deep invasion into the stroma. We report a series of 10 cases, all extending less than 1 mm from the basement membrane. Our results support the hypothesis that adenoid basal hyperplasia arises from reserve cells of the cervix. Lesions were found close to the squamocolumnar junction, in continuity with the nearby subcolumnar reserve cells. They shared the same morphology and immunoprofile using a panel of 4 antibodies (keratin 5/6, keratin 14, keratin 7 and p63) designed to differentiate reserve cells from mature squamous cells and endocervical columnar cells...
December 2012: Human Pathology
https://www.readbyqxmd.com/read/22679170/adenoid-cystic-carcinoma-of-the-breast-with-cerebral-metastisation-a-clinical-novelty
#13
Ines Silva, Vera Tome, Joao Oliveira
Adenoid cystic carcinoma (ACC) is a rare variant of adenocarcinoma of the breast. It affects mainly minor and major salivary glands, but may also occur in many others locations such as: breast (<1% of all breast cancers), lung, trachea, cervix and Bartholin's gland. Its prognosis is excellent, contrary to the extra-mammary form. In fact, metastisation is rare (there are only seven clinical cases with metastisation described in literature and the lung is the most affected organ) and when it occurs, generally, there is no axillary node involvement...
2011: BMJ Case Reports
https://www.readbyqxmd.com/read/22390868/-adenoid-cystic-carcinoma-of-the-uterine-cervix
#14
Péter Sámuel Nagy, Zoltán Tóth, Péter Gocze, László Adám
This report presents the history of a 35-year-old patient with adenoid cystic cervical cancer stage IIIB. Adenoid cystic carcinoma of the uterine cervix is a rare disease with poor prognosis. Following irradiation therapy, the patient was declared tumor free, and 20 years after diagnosis and treatment, she has no pathological signs or symptoms.
March 18, 2012: Orvosi Hetilap
https://www.readbyqxmd.com/read/22123720/adenoid-basal-carcinoma-of-the-uterine-cervix-clinicopathologic-features-of-12-cases-with-reference-to-cd117-expression
#15
Tai-Di Chen, Huei-Chieh Chuang, Li-yu Lee
Adenoid basal carcinoma is a rare tumor of the uterine cervix. Less than 100 cases have been documented thus far, and only a few cases have been reported among the Asian population. An important differential diagnosis is cervical adenoid cystic carcinoma because of their overlapping morphologic appearances but absolutely different clinical outcomes. The treatment of adenoid basal carcinoma should be conservative due to its generally benign behavior. CD117 (c-kit) have been recently found immunohistochemically positive for adenoid cystic carcinomas of other anatomic locations and may serve as a useful ancillary differential marker...
January 2012: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/21556544/monoclonal-antibodies-5g8-and-2h6-are-complementary-immunohistochemical-markers-of-lung-carcinomas
#16
K Joh, T Sekine, K Ohkawa, S Aizawa
Two murine monoclonal antibodies (MAbs) 5G8 and 2H6 were generated by fusing spleen cells obtained from mice immunized with human fetal tissue extract (14 weeks, Nonidet P-40 membrane fraction) from the early first trimester, followed by a booster injection of a lung cancer cell line. The MAb 5G8 recognized antigens with a molecular weight of 90, 50, 20 kDa, was neuraminidase-resistant and showed cross-reactivity with both carcinoembryonic antigen and non-specific cross-reacting antigen. The MAb 2H6 reacted with a sialomucin whose molecular weight was more than 1000 kDa and was different from previously known tumor associated-marker antigens...
February 1995: International Journal of Oncology
https://www.readbyqxmd.com/read/21053595/adenoid-cystic-carcinoma-in-the-uterine-cervix-a-case-report
#17
Dilleswari Pradhan, Kaumudee Pattnaik, Jagannath Pahi, Pranati Mohanty, Surama Satpathy, Sasmita Behuria
BACKGROUND: Adenoid cystic carcinoma, a variant of adenocarcinoma of the uterine cervix, is an extremely rare neoplasm. This report describes a case of primary adenoid cystic carcinoma of the uterine cervix and includes the cytopathologic and histopathologic findings. CASE: A 55-year-old woman presented with postmenopausal bleeding for 2 months. Speculum examination showed a firm mass in the uterine cervix. A Pap smear was obtained, which showed small epithelial cells with hyperchromatic nuclei and coarse chromatin dispersed and adhered around hyaline stromal globular material, along with a few atypical squamous cells...
September 2010: Acta Cytologica
https://www.readbyqxmd.com/read/20432755/cytologic-characteristics-of-adenoid-cystic-carcinoma-of-the-cervix-uteri-case-report
#18
Ana Barisić, Vesna Mahovlić, Ana Ovanin-Rakić, Lada Skopljanac-Macina, Sanda Rajhvajn, Danijela Juric, Damir Babić
Adenoid cystic carcinoma is a rare malignancy, usually found in the salivary glands, although this unusual tumor can be found at other sites of the body. In particular, regarding adenoid cystic carcinoma of the cervix (ACCC) most frequently reports are given for postmenopausal women. In this respect, our work is one among very few in the literature that considers a cytologic picture of this uncommon cervix carcinoma. The case of 74 year old patient with postmenopausal bleeding is described. Both Pap smear and air dried smear of the uterine cervix were analyzed...
March 2010: Collegium Antropologicum
https://www.readbyqxmd.com/read/19829837/advanced-adenoid-cystic-carcinoma-of-the-cervix-a-case-report-and-review-of-the-literature
#19
Lalla Kawtar Elhassani, Hind Mrabti, Nabil Ismaili, Youssef Bensouda, Ouafae Masbah, Imane Bekkouch, Khalid Hassouni, Fouad Kettani, Hassan Errihani
INTRODUCTION: Adenoid cystic carcinoma is a malignant epithelial neoplasm derived from the salivary glands. Primary adenoid cystic carcinoma of the cervix is extremely rare, accounting for less than 1% of all cervical carcinomas. In this paper we report a case of primary adenoid cystic carcinoma and a review of the related literature. CASE PRESENTATION: A 68 year-old woman was admitted with signs and symptoms suggestive of a cervical cancer. The radiological and pathological investigations confirmed the diagnostic of primary adenoid cystic carcinoma of the cervix at Stage IIIB according to the International Federation of Gynaecology and Obstetrics classification...
2009: Cases Journal
https://www.readbyqxmd.com/read/19805968/adenoid-cystic-carcinoma-of-uterine-cervix-in-a-young-patient
#20
Ankit Seth, Asha Agarwal
Adenoid cystic carcinoma of uterine cervix is a rare tumor. Its origin is debatable. It has a high incidence in postmenopausal women but rarely can develop in patients under 40. An association with squamous cell carcinoma has been described. We report a case of adenoid cystic carcinoma of the endocervical canal with foci of squamous cell carcinoma in a 34-year-old suffering from menorrhagia associated with blood-stained vaginal discharge. Per vaginum and per speculum examination revealed a growth. Cervical biopsy showed bits of tissue, suggesting adenoid cystic carcinoma...
October 2009: Indian Journal of Pathology & Microbiology
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