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Migrain update

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https://www.readbyqxmd.com/read/28424953/treatment-update-of-chronic-migraine
#1
REVIEW
Soo-Jin Cho, Tae-Jin Song, Min Kyung Chu
PURPOSE OF REVIEW: Although chronic migraine (CM) is a common disorder that severely impacts patient functioning and quality of life, it is usually underdiagnosed, and treatment responses often remain poor even after diagnosis. In addition, effective treatment options are limited due to the rarity of randomized controlled trials (RCTs) involving patients with CM. In the present review, we discuss updated pharmacological, non-pharmacological, and neurostimulation treatment options for CM...
June 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28388266/neurological-disease-in-women-stroke-cognition-and-headache
#2
Lisa N Kransdorf, Anita P Mayer, Julia A Files
In this clinical update, we selected recent publications relevant to common neurological concerns in women, with specific attention to stroke, cognition, and headache. We have chosen to highlight articles on sex differences in stroke and stroke treatment, the effect of hormone therapy on stroke risk and on cognition, and symptoms of the migraine postdrome.
April 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28321564/an-update-on-migraine-current-understanding-and-future-directions
#3
Francesca Puledda, Roberta Messina, Peter J Goadsby
Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase in the interest around migraine pathophysiology has allowed researchers to unravel certain neurophysiological mechanisms and neurotransmitter involvement culminating in the recent development of novel therapies, which might substantially change the clinical approach to migraine patients. The present review will highlight the current aspects of migraine pathophysiology, covering an understanding of the complex workings of the migraine state and the brain regions responsible for them...
March 20, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28295242/an-update-on-non-pharmacological-neuromodulation-for-the-acute-and-preventive-treatment-of-migraine
#4
REVIEW
Francesca Puledda, Peter J Goadsby
OBJECTIVE: To review current neuromodulation treatments available for migraine therapy, both in the acute and preventive setting. METHODS: The published literature was reviewed for studies reporting the effects of different neuromodulation strategies in migraine with and without aura. The use of non-invasive: single pulse transcranial magnetic stimulation, non-invasive vagal nerve stimulation, supraorbital nerve stimulation, and transcranial direct current stimulation, as well as invasive methods such as occipital nerve stimulation and sphenopalatine ganglion stimulation, are assessed...
April 2017: Headache
https://www.readbyqxmd.com/read/28285826/the-clinical-manifestations-of-vestibular-migraine-a-review
#5
REVIEW
Ashley P O'Connell Ferster, Adrian J Priesol, Huseyin Isildak
OBJECTIVES: To provide an overview of vestibular migraines presentation, pathology, and diagnosis, as well as an update on current diagnostic criteria. METHODS: A review of the most recent literature on vestibular migraines was performed. RESULTS: Vestibular migraine is a process with significant impact on the quality of life for those afflicted with the disease, with attacks of spontaneous or positional vertigo and migraine symptoms lasting several minutes to 72h...
March 9, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28240609/migraine-and-magnetic-resonance-spectroscopy-a-systematic-review
#6
Samaira Younis, Anders Hougaard, Mark B Vestergaard, Henrik B W Larsson, Messoud Ashina
PURPOSE OF REVIEW: To present an updated and streamlined overview of the metabolic and biochemical aspect of the migraine pathophysiology based on findings from phosphorous (P) and hydrogen (H) magnetic resonance spectroscopy (MRS) studies. RECENT FINDINGS: Despite of the variation in the methodology and quality of the MRS migraine studies over time, some results were consistent and reproducible. P-MRS studies suggested reduced availability of neuronal energy and implied a mitochondrial dysfunction in the migraine brain...
June 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28150221/the-association-between-brain-derived-neurotrophic-factor-gene-polymorphism-and-migraine-a-meta-analysis
#7
REVIEW
Xiaoying Cai, Xiaolei Shi, Ximeng Zhang, Aiwu Zhang, Minying Zheng, Yannan Fang
BACKGROUND: Migraine is a recurrent headache disease related to genetic variants. The brain-derived neurotrophic factor (BDNF) gene rs6265 (Val66Met) and rs2049046 polymorphism has been found to be associated with migraine. However, their roles in this disorder are not well established. Then we conduct this meta-analysis to address this issue. METHODS: PubMed, Web of Science and Cochrane databases were systematically searched to identify all relevant studies. Odds ratio (OR) with corresponding 95% confidence interval (CI) was used to estimate the strength of association between BDNF gene rs6265 and rs2049046 polymorphism and migraine...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28042767/advantages-of-structure-based-drug-design-approaches-in-neurological-disorders
#8
Murali Aarthy, Umesh Panwar, Chandrabose Selvaraj, Sanjeev Kumar Singh
The nerve impulse that function during abnormal or due in illness may due to several genetic factors, metabolic, biological conditions or environmental components denominated as Neuro-biological disorders. This illness occurs mostly due to the innumerable biological modifications that alters the mechanistic condition of the brain. As per current update, more than a millions of people around the world are suffering through various kinds of neurological disorders. In case, 50 million people with Epilepsy, 35 million with dementia, mainly included Alzheimer's disease and the rest of other cases with Parkinson's, Migraine and Stroke...
January 2, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/27910097/chronic-migraine-an-update-on-physiology-imaging-and-the-mechanism-of-action-of-two-available-pharmacologic-therapies
#9
Sheena K Aurora, Mitchell F Brin
Several lines of research support the hypothesis that migraine is a spectrum of illness, with clinical symptoms that vary along a continuum from episodic migraine to chronic migraine. Physiologic changes may result in episodic migraine evolving into chronic migraine over months to years in susceptible individuals. With chronification, headache frequency increases, becoming more disabling and less responsive to therapy. Neurophysiologic and functional imaging research has reported that chronic migraine may be associated with severity-specific metabolic, functional, and structural abnormalities in the brainstem...
January 2017: Headache
https://www.readbyqxmd.com/read/27873122/how-well-does-the-ichd-3-beta-help-in-real-life-migraine-diagnosis-and-management
#10
REVIEW
Sait Ashina, Jes Olesen, Richard B Lipton
Classification has played a major role in the diagnosis of primary headache conditions including migraine with and without aura. With many updates and changes, the International Classification of Headache Disorders (ICHD)-3 beta is currently considered as the gold standard for classification of migraine and other headaches. Correct diagnosis of migraine and its subtypes is a first step toward appropriate treatment and crucial to minimizing disability and optimizing health-related quality of life. The ICHD-3 beta version represents the state of the art in migraine diagnosis but is expected to evolve as biological knowledge advances...
December 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27864731/multiple-sclerosis-related-pain-syndromes-an-imaging-update
#11
REVIEW
Amir Mazhari
Pain in multiple sclerosis (MS) is a common manifestation, made up of complex phenomenon involving intricate neurophysiological processing at central levels of the pain pathway. Our understanding of the clinical and neurophysiological mechanisms of central/neuropathic pain related to MS continues to improve with improved imaging techniques but remains a challenging area of research. The advancements in imaging techniques for lesion evaluation of the various neuroanatomic structures have improved our detection, diagnosis, and understanding of MS pain and help validate subjective symptoms...
December 2016: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/27785579/migraine-and-the-risk-of-stroke-an-updated-meta-analysis-of-prospective-cohort-studies
#12
REVIEW
Xianming Hu, Yingchun Zhou, Hongyang Zhao, Cheng Peng
Dozens of observational studies and two meta-analyses have investigated the association of migraine with the risk of stroke, but their results are inconsistent. We aimed to quantitatively evaluate the relationship between migraine and stroke risk by performing a meta-analysis of prospective cohort studies. PubMed and Embase were searched through July 2016 to identify studies that met pre-stated inclusion criterion and reference lists of retrieved articles were also reviewed. Information on the characteristics of the included study, risk estimates, and control for possible confounding factors were extracted independently by two authors...
January 2017: Neurological Sciences
https://www.readbyqxmd.com/read/27733282/global-regional-and-national-incidence-prevalence-and-years-lived-with-disability-for-310-diseases-and-injuries-1990-2015-a-systematic-analysis-for-the-global-burden-of-disease-study-2015
#13
COMMENT
(no author information available yet)
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015...
October 8, 2016: Lancet
https://www.readbyqxmd.com/read/27658514/-non-criteria-neurologic-manifestations-of-antiphospholipid-syndrome-a-hidden-kingdom-to-be-discovered
#14
Md Asiful Islam, Fahmida Alam, Mohammad Amjad Kamal, Kah Keng Wong, Teguh Haryo Sasongko, Siew Hua Gan
Neurological manifestations or disorders associated with central nervous system (CNS) are one of the most common as well as important clinical characteristics of antiphospholipid syndrome (APS). Although in the last updated (2006) classification criteria of APS its neurological manifestations encompassed only transient ischemic attack (TIA) and stroke, diverse 'non-criteria' neurological disorders or manifestations (headache, migraine, bipolar disorder, transverse myelitis, dementia, chorea, epileptic seizures, multiple sclerosis, psychosis, cognitive impairment, Tourette's syndrome, parkinsonism, dystonia, transient global amnesia, obsessive compulsive disorder and leukoencephalopathy) have been observed in APS patients...
September 20, 2016: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/27582896/eletriptan-in-the-management-of-acute-migraine-an-update-on-the-evidence-for-efficacy-safety-and-consistent-response
#15
REVIEW
Matilde Capi, Martina Curto, Luana Lionetto, Fernando de Andrés, Giovanna Gentile, Andrea Negro, Paolo Martelletti
Migraine is a multifactorial, neurological and disabling disorder, also characterized by several autonomic symptoms. Triptans, selective serotonin 5-HT1B/1D agonists, are the first-line treatment option for moderate-to-severe headache attacks. In this paper, we review the recent data on eletriptan clinical efficacy, safety, and tolerability, and potential clinically relevant interactions with other drugs. Among triptans, eletriptan shows a consistent and significant clinical efficacy and a good tolerability profile in the treatment of migraine, especially for patients with cardiovascular risk factors without coronary artery disease...
September 2016: Therapeutic Advances in Neurological Disorders
https://www.readbyqxmd.com/read/27557333/evaluation-of-wet-cupping-therapy-systematic-review-of-randomized-clinical-trials
#16
REVIEW
Abdullah M N Al Bedah, Mohamed K M Khalil, Paul Posadzki, Imen Sohaibani, Tamer Shaaban Aboushanab, Meshari AlQaed, Gazzaffi I M Ali
BACKGROUND: Wet cupping is a widely used traditional therapy in many countries, which justifies a continuous scientific evaluation of its efficacy and safety. OBJECTIVES: To perform a systematic review to critically evaluate and update the available evidence of wet cupping in traditional and complementary medicine. METHODS: Ten electronic databases were searched from their inceptions to February 2016. Included studies were randomized clinical trials (RCTs) that evaluated wet cupping against any type of control interventions in patients with any clinical condition, as well as healthy individuals...
October 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/27513702/melatonin-as-add-on-treatment-for-epilepsy
#17
REVIEW
Francesco Brigo, Stanley C Igwe, Alessandra Del Felice
BACKGROUND: This is an updated version of the original Cochrane review published in Issue 6, 2012.Epilepsy is one of the most common chronic neurological disorders. Despite the plethora of antiepileptic drugs (AEDs) currently available, 30% of people continue having seizures. This group of people requires a more aggressive treatment, since monotherapy, the first choice scheme, fails to control seizures. Nevertheless, polytherapy often results in a number of unwanted effects, including neurological disturbances (somnolence, ataxia, dizziness), psychiatric and behavioural symptoms, and metabolic alteration (osteoporosis, inducement or inhibition of hepatic enzymes, etc...
August 11, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27467196/u-s-medical-eligibility-criteria-for-contraceptive-use-2016
#18
Kathryn M Curtis, Naomi K Tepper, Tara C Jatlaoui, Erin Berry-Bibee, Leah G Horton, Lauren B Zapata, Katharine B Simmons, H Pamela Pagano, Denise J Jamieson, Maura K Whiteman
The 2016 U.S. Medical Eligibility Criteria for Contraceptive Use (U.S. MEC) comprises recommendations for the use of specific contraceptive methods by women and men who have certain characteristics or medical conditions. These recommendations for health care providers were updated by CDC after review of the scientific evidence and consultation with national experts who met in Atlanta, Georgia, during August 26-28, 2015. The information in this report updates the 2010 U.S. MEC (CDC. U.S. medical eligibility criteria for contraceptive use, 2010...
July 29, 2016: MMWR. Recommendations and Reports: Morbidity and Mortality Weekly Report. Recommendations and Reports
https://www.readbyqxmd.com/read/27413503/update-on-normal-tension-glaucoma
#19
REVIEW
Jyotiranjan Mallick, Lily Devi, Pradeep K Malik, Jogamaya Mallick
Normal tension glaucoma (NTG) is labelled when typical glaucomatous disc changes, visual field defects and open anterior chamber angles are associated with intraocular pressure (IOP) constantly below 21 mmHg. Chronic low vascular perfusion, Raynaud's phenomenon, migraine, nocturnal systemic hypotension and over-treated systemic hypertension are the main causes of normal tension glaucoma. Goldmann applanation tonometry, gonioscopy, slit lamp biomicroscopy, optical coherence tomography and visual field analysis are the main tools of investigation for the diagnosis of NTG...
April 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27389092/chronic-migraine-risk-factors-mechanisms-and-treatment
#20
REVIEW
Arne May, Laura H Schulte
Chronic migraine has a great detrimental influence on a patient's life, with a severe impact on socioeconomic functioning and quality of life. Chronic migraine affects 1-2% of the general population, and about 8% of patients with migraine; it usually develops from episodic migraine at an annual conversion rate of about 3%. The chronification is reversible: about 26% of patients with chronic migraine go into remission within 2 years of chronification. The most important modifiable risk factors for chronic migraine include overuse of acute migraine medication, ineffective acute treatment, obesity, depression and stressful life events...
August 2016: Nature Reviews. Neurology
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