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https://www.readbyqxmd.com/read/28438383/remitting-seronegative-symmetrical-synovitis-with-pitting-edema-rs3pe-syndrome-induced-by-nivolumab
#1
Marie-Léa Gauci, Barouyr Baroudjian, Pauline Laly, Isabelle Madelaine, Laetitia Da Meda, Laetitia Vercellino, Martine Bagot, Frédéric Lioté, Cécile Pages, Céleste Lebbé
INTRODUCTION: A new articular syndrome described as immunrelated side effect of immunotherapy: PD-1 inhibitors have revolutionized the treatment of advanced melanoma but are responsible for immune-related toxicity. We report a case of remitting seronegative symetrical synovitis with pitting edema (RS3PE) syndrome induced by nivolumab. CASE REPORT: A 80 year-old man with stage IV BRAF-wild type and NRAS exon 2-mutated melanoma was treated first line by nivolumab 3mg/kg every 2 weeks...
March 8, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28427100/dystrophinopathies-and-limb-girdle-muscular-dystrophies
#2
Joana Domingos, Anna Sarkozy, Mariacristina Scoto, Francesco Muntoni
Muscular dystrophies are a heterogeneous group of inherited diseases. The natural history of these disorders along with their management have changed mainly due to a better understanding of their pathophysiology, the evolution of standards of care, and new treatment options. Dystrophinopathies include both Duchenne's and Becker's muscular dystrophies, but in reality they are a spectrum of muscle diseases caused by mutations in the gene that encodes the protein dystrophin. Duchenne's muscular dystrophy is the most common form of inherited muscle disease of childhood...
April 20, 2017: Neuropediatrics
https://www.readbyqxmd.com/read/28418359/-a-rare-concurrence-of-polymyalgia-rheumatica-and-aa-amyloidosis
#3
S G Radenska-Lopovok, O N Kotenko, N F Frolova, A I Zagrebneva, E S Stolyarevich, E V Volodina, V I Chervinko, E V Kryukov, M L Zubkin
Polymyalgia rheumatica (PMR) is a rare chronic inflammatory disease. It predominantly affects the elderly. The disease has a slow onset, pain and stiffness in the muscles of the shoulder and pelvic girdle, fever, weight loss, and a high acute-phase inflammatory response. The disease is concurrent with giant cell arteritis in a quarter of cases, which allows some authors to consider them as two different manifestations of the same pathological process. The kidneys are rarely involved. This disease is rarely complicated by AA amyloidosis...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28409140/osteoid-osteoma-of-the-distal-clavicle
#4
Bernardo Barcellos Terra, Leandro Marano Rodrigues, David Victoria Hoffmann Padua, Tannous Jorge Sassine, José Maria Cavatte, Anderson De Nadai
The osteoid osteoma is a bone tumor that accounts for 10% of benign tumors. It was described in 1935 by Jaffe, as a tumor that affects the young adult population, with a predominance of males. This study aims to present a case of late diagnosis of a patient with osteoid osteoma of the distal clavicle region. Female patient, 44 years old, non-professional volleyball player, reported pain in the anterior and superior region of the shoulder girdle, specifically in the acromioclavicular joint, which worsened at night and had been treated for nine months as tendinitis of the rotator cuff and acromioclavicular joint arthritis...
March 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28406877/scapulothoracic-dissociation-evaluation-and-management
#5
Andrew M Choo, Patrick C Schottel, Andrew R Burgess
Scapulothoracic dissociation is a rare, potentially limb- and life-threatening injury of the shoulder girdle. The injury is characterized by lateral displacement of the scapula resulting from traumatic disruption of the scapulothoracic articulation. The typical physical examination findings consist of substantial swelling of the shoulder girdle, along with weakness, numbness, and pulselessness in the ipsilateral upper extremity. Radiographic evaluation includes measurement of the scapular index on a nonrotated chest radiograph and assessment for either a distracted clavicle fracture or a disrupted acromioclavicular or sternoclavicular joint...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28364009/imaging-findings-in-patients-with-zoster-associated-plexopathy
#6
A S Zubair, C Hunt, J Watson, A Nelson, L K Jones
Herpes zoster is a reactivation of the latent varicella zoster virus. Among the complications of herpes zoster is zoster-associated limb paresis. The clinical and imaging features of patients with zoster-associated limb paresis due to plexopathies (zoster-associated plexopathy) have had limited description in the literature. The Mayo Clinic patient data base was searched by diagnostic code for patients diagnosed with herpes zoster between January 1, 1996, and September 30, 2012. Patients who met the inclusion criteria for zoster-associated limb paresis or herpes zoster with MRIs obtained were reviewed...
March 31, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28361653/hand-function-in-muscular-dystrophies
#7
Mariana C Artilheiro, Cristina Dos Santos Cardoso de Sá, Francis M Fávero, Hanna C Wutzki, Maria Bernadete Dutra de Resende, Fátima A Caromano, Mariana C Voos
The aim of this study was to investigate the relationship between Performance of Upper Limb (PUL) and Jebsen-Taylor Test (JTT) to assess and monitor upper limb function progression in patients with muscular dystrophy. Thirty patients diagnosed with Duchenne muscular dystrophy, limb-girdle muscular dystrophy, Becker muscular dystrophy, myotonic dystrophy Type 1, and fascioscapulohumeral dystrophy were submitted to the shoulder, elbow, and wrist domains of PUL, and to JTT subtests. Spearman tests investigated the relationships between PUL and JTT total scores and domains...
April 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/28350234/inclined-weight-loaded-walking-at-different-speeds-pelvis-shoulder-coordination-trunk-movements-and-cost-of-transport
#8
Rodrigo Gomes da Rosa, Natalia Andrea Gomeñuka, Henrique Bianchi de Oliveira, Leonardo Alexandre Peyré-Tartaruga
Although studied at level surface, the trunk kinematics and pelvis-shoulder coordination of incline walking are unknown. The aim of this study was to evaluate the speed effects on pelvis-shoulder coordination and trunk movement and the cost of transport (C) during unloaded and loaded (25% of body mass) 15% incline walking. We collected 3-dimensional kinematic and oxygen consumption data from 10 physically active young men. The movements were analyzed in the sagittal plane (inclination and range of trunk motion) and the transverse plane (range of shoulder and pelvic girdle motion and phase difference)...
March 28, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28279851/the-sensitivity-of-shoulder-muscle-and-joint-force-predictions-to-changes-in-joint-kinematics-a-monte-carlo-analysis
#9
Wen Wu, Peter Vee Sin Lee, David C Ackland
Kinematics of the shoulder girdle obtained from non-invasive measurement systems such as video motion analysis, accelerometers and magnetic tracking sensors has been shown to be adversely affected by instrumentation measurement errors and skin motion artefact. The degree to which musculoskeletal model calculations of shoulder muscle and joint loading are influenced by variations in joint kinematics is currently not well understood. A three-dimensional musculoskeletal model of the upper limb was used to evaluate the sensitivity of shoulder muscle and joint force...
March 1, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28276913/postural-stability-clicker-reaction-time-and-bow-draw-force-predict-performance-in-elite-recurve-archery
#10
Wayne Spratford, Rhiannon Campbell
Recurve archery is an Olympic sport that requires extreme precision, upper body strength and endurance. The purpose of this research was to quantify how postural stability variables both pre- and post-arrow release, draw force, flight time, arrow length and clicker reaction time, collectively, impacted on the performance or scoring outcomes in elite recurve archery athletes. Thirty-nine elite-level recurve archers (23 male and 16 female; mean age = 24.7 ± 7.3 years) from four different countries volunteered to participate in this study prior to competing at a World Cup event...
February 14, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28275882/management-of-chronic-unstable-acromioclavicular-joint-injuries
#11
REVIEW
Luis Natera Cisneros, Juan Sarasquete Reiriz
The acromioclavicular joint represents the link between the clavicle and the scapula, which is responsible for the synchronized dynamic of the shoulder girdle. Chronic acromioclavicular joint instability involves changes in the orientation of the scapula, which provokes cinematic alterations that might result in chronic pain. Several surgical strategies for the management of patients with chronic and symptomatic acromioclavicular joint instability have been described. The range of possibilities includes anatomical and non-anatomical techniques, open and arthroscopy-assisted procedures, and biological and synthetic grafts...
March 8, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28273959/morphometric-evaluation-of-adult-acromion-process-in-north-indian-population
#12
Susmita Saha, Neelam Vasudeva
INTRODUCTION: Dimensions of acromion process are important to show linkage to the shoulder girdle pathologies. Also morphometric analysis of acromion process would be helpful for surgeons while performing surgical procedures on the shoulder joint. AIM: The purpose of this present study was to observe the detailed morphometric evaluation of adult acromion processes in North Indian population because different morphometric dimensions play an important role in various disorders of the shoulder, particularly sub acromial impingement syndrome...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28264546/sonographic-guide-for-botulinum-toxin-injections-of-the-upper-limb-euro-musculus-usprm-spasticity-approach
#13
Murat Kara, Bayram Kaymak, Alper M Ulaşli, Fatih Tok, Gokhan T Öztürk, Ke-Vin Chang, Ming-Yen Hsiao, Chen-Yu Hung, Arzu Yağiz On, Levent Özçakar
The pertinent literature lacks overt technical data for optimal upper limb muscle botulinum toxin injections using ultrasound (US) imaging. Therefore, this guide is prepared for the commonly injected muscles of the upper limb and the shoulder girdle mainly in spasticity. It includes clinical information, anatomical description and explanation regarding the US imaging of several muscles. The figures have been organized to orient the readers on the innervation zones, injection sites, probe positionings and the US images simultaneously...
March 6, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28217183/affection-of-the-respiratory-muscles-in-combined-complex-i-and-iv-deficiency
#14
Josef Finsterer, Helmut Rauschka, Liane Segal, Gabor G Kovacs, Boris Rolinski
OBJECTIVES: Combined complex I+IV deficiency has rarely been reported to manifest with the involvement of the respiratory muscles. CASE REPORT: A 45y male was admitted for hypercapnia due to muscular respiratory insufficiency. He required intubation and mechanical ventilation. He had a previous history of ophthalmoparesis since age 6y, ptosis since age 23y, and anterocollis since at least age 40y. Muscle biopsy from the right deltoid muscle at age 41y was indicative of mitochondrial myopathy...
2017: Open Neurology Journal
https://www.readbyqxmd.com/read/28206991/a-jurassic-stem-pleurodire-sheds-light-on-the-functional-origin-of-neck-retraction-in-turtles
#15
Jérémy Anquetin, Haiyan Tong, Julien Claude
Modern turtles are composed of two monophyletic groups, notably diagnosed by divergent neck retraction mechanisms. Pleurodires (side-necked turtles) bend their neck sideways and protect their head under the anterior margin of the carapace. Cryptodires (hidden-necked turtles) withdraw their neck and head in the vertical plane between the shoulder girdles. These two mechanisms of neck retraction appeared independently in the two lineages and are usually assumed to have evolved for protective reasons. Here we describe the neck of Platychelys oberndorferi, a Late Jurassic early stem pleurodire, and find remarkable convergent morphological and functional similarities with modern cryptodires...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28193127/relations-between-the-results-of-complex-clinical-and-neurophysiological-examinations-in-patients-with-temporomandibular-disorders-symptoms
#16
Anna Sójka, Juliusz Huber, Wiesław Hędzelek, Agnieszka Wiertel-Krawczuk, Agnieszka Szymankiewicz-Szukała, Agnieszka Seraszek-Jaros, Aleksandra Kulczyk, Agnieszka Wincek, Magdalena Sobieska
OBJECTIVE: Reinvestigation of clinical importance of surface electromyography recordings (sEMG) from the masticatory, neck and shoulder girdle muscles in patients with various clinically detected temporomandibular disorders (TMDs). METHODS: Fifty women with myalgia diagnosis of Axis I DC/TMD and the same number of healthy female volunteers were studied clinically and neurophysiologically by means of sEMG. RESULTS: Unilateral more than bilateral complex symptoms of TMDs were related to the non-neurogenic masticatory rather than neck and shoulder girdle muscles dysfunctions at rest...
February 14, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/28185265/teres-major-muscle-insertion-footprint
#17
Malte Dancker, Simon Lambert, Erich Brenner
Teres major muscle (TM) and latissimus dorsi muscle (LD) are frequently used in muscle transfers around the shoulder girdle. Some authors have suggested harvesting techniques in which the muscle is detached in continuity with a bone segment. Information on the bony attachment footprint of these muscles is lacking. The purpose of this study was to investigate the region of attachment of the TM to facilitate safe and complete harvesting with a bone segment where it is indicated, and to determine the relationship of the TM footprint with that of the LD...
May 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28164062/case-report-of-mimicry-between-synovial-hemangioma-and-synovial-chondromatosis-of-the-shoulder
#18
Justin Colanese, Akin Cil, Nkem Egekeze, Kamani Lankachandra, Suhel Kotwal
INTRODUCTION: Synovial hemangioma is a developmental hamartoma of vascular tissue within the synovium; no cases involving the shoulder girdle have been described in the literature. Synovial chondromatosis is a benign condition in which synovial cells undergo metaplasia into hyaline cartilage and is also thought to infrequently affect the shoulder region. CASE REPORT: A 44-year-old female presented with left shoulder pain of 7-year duration. Magnetic resonance image displayed a 2...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28157257/compound-heterozygous-pomt1-mutations-in-a-chinese-family-with-autosomal-recessive-muscular-dystrophy-dystroglycanopathy-c1
#19
Pengzhi Hu, Song Wu, Lamei Yuan, Qiongfen Lin, Wen Zheng, Hong Xia, Hongbo Xu, Liping Guan, Hao Deng
Muscular dystrophy-dystroglycanopathy (MDDG) is a genetically and clinically heterogeneous group of muscular disorders, characterized by congenital muscular dystrophy or later-onset limb-girdle muscular dystrophy accompanied by brain and ocular abnormalities, resulting from aberrant alpha-dystroglycan glycosylation. Exome sequencing and Sanger sequencing were performed on a six-generation consanguineous Han Chinese family, members of which had autosomal recessive MDDG. Compound heterozygous mutations, c.1338+1G>A (p...
February 3, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28149720/arthroscopically-assisted-acromioclavicular-and-coracoclavicular-ligament-reconstruction-for-chronic-acromioclavicular-joint-instability
#20
Frank Martetschläger, Mark Tauber, Peter Habermeyer, Nael Hawi
Acromioclavicular (AC) joint injuries are common injuries, especially in the young and active, male population. AC joint injuries account for 12% of all injuries of the shoulder girdle in the overall population. Although conservative treatment is recommended for Rockwood type I and type II injuries, there is controversial debate about optimal treatment for type III injuries. High-grade injuries are typically treated operatively to avoid painful sequelae. A vast number of different surgical methods have been described over the past few decades...
December 2016: Arthroscopy Techniques
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