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trigeminal neuralgia treatment

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https://www.readbyqxmd.com/read/28087952/an-observational-study-of-trigeminal-neuralgia-patients-taking-carbamazepine-during-the-fasting-month-of-ramadan
#1
A J Ajura, S H Lau, S Nur Suffia
INTRODUCTION: Trigeminal neuralgia is an agonising orofacial pain affecting unilaterally the distribution of the trigeminal nerve and it usually occurs in the middle and older age groups. Carbamazepine which is an anti-neuralgic as well as an anti-convulsant medication is the first line drug for treatment of trigeminal neuralgia. It is commonly taken as one tablet (200 mg) three times a day. MATERIALS AND METHODS: This is an observational study carried out from April to September 2014 to determine how Muslim patients on carbamazepine treatment for trigeminal neuralgia cope with their neuralgic pain...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28076964/trigeminal-neuralgia-diagnosis-and-treatment
#2
Stine Maarbjerg, Giulia Di Stefano, Lars Bendtsen, Giorgio Cruccu
Introduction Trigeminal neuralgia (TN) is characterized by touch-evoked unilateral brief shock-like paroxysmal pain in one or more divisions of the trigeminal nerve. In addition to the paroxysmal pain, some patients also have continuous pain. TN is divided into classical TN (CTN) and secondary TN (STN). Etiology and pathophysiology Demyelination of primary sensory trigeminal afferents in the root entry zone is the predominant pathophysiological mechanism. Most likely, demyelination paves the way for generation of ectopic impulses and ephaptic crosstalk...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28063126/a-retrospective-study-of-neurocombing-for-the-treatment-of-trigeminal-neuralgia-without-neurovascular-compression
#3
X Liang, X Dong, S Zhao, X Ying, Y Du, W Yu
BACKGROUND: Microvascular decompression (MVD) is the most effective and non-ablative treatment for trigeminal neuralgia (TN). However, it is not possible when neurovascular compression (NVC) is absent. Neurocombing is a possible treatment option for TN patients without NVC. AIM: To evaluate and describe the clinical outcome of neurocombing for the treatment of TN when NVC was absent. METHODS: We retrospectively reviewed the clinical data of the 37 patients of Type 1 TN without NVC who underwent neurocombing in our department between January 2013 and November 2014...
January 6, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28047547/su-f-t-647-linac-based-stereotactic-radiosurgery-srs-in-the-treatment-of-trigeminal-neuralgia-detailed-description-of-srs-procedural-technique-and-reported-clinical-outcomes
#4
D Pokhrel, S Sood, R Badkul, H Jiang, T Stepp, P Camarata, F Wang
PURPOSE: SRS is an effective non-invasive alternative treatment modality with minimal-toxicity used to treat patients with medically/surgically refractory trigeminal neuralgia root(TNR) or those who may not tolerate surgical intervention. We present our linac-based SRS procedure for TNR treatment and simultaneously report our clinical outcomes. METHODS: Twenty-eight TNR-patients treated with frame-based SRS at our institution (2009-2015) with a single-fraction point-dose of 60-80Gy to TNR were included in this IRB-approved study...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046293/su-f-t-631-linear-accelerator-based-frameless-extracranial-radiosurgery-for-treatment-of-occipital-neuralgia-for-non-surgical-candidates
#5
T Denton, J Howe, A Spalding
PURPOSE: Occipital neuralgia is a condition wherein pain is transmitted by the occipital nerves. Non-invasive therapies generally alleviate symptoms; however, persistent or recurring pain may require invasive procedures. Repeated invasive procedures upon failure are considered higher risk and are often contraindicated due to compounding inherent risk. SRS has not been explored as a treatment option largely due to the extracranial nature of the target (as opposed to the similar, more established trigeminal neuralgia), but advances in linear-accelerator frameless-based SRS now present an opportunity to evaluate the novel potential of this modality for this application...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046289/su-f-j-160-clinical-evaluation-of-targeting-accuracy-in-radiosurgery-using-tractography
#6
R Juh, T Suh, J Han, C Kim, C Oh
PURPOSE: Focal radiosurgery is a common treatment modality for trigeminal neuralgia (TN), a neuropathic facial pain condition. Assessment of treatment effectiveness is primarily clinical, given the paucity of investigational tools to assess trigeminal nerve changes. The efficiency of radiosurgery is related to its highly precise targeting. We assessed clinically the targeting accuracy of radiosurgery with Gamma knife. We hypothesized that trigeminal tractography provides more information than 2D-MR imaging, allowing detection of unique, focal changes in the target area after radiosurgery...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043642/-maxillary-trigeminal-schwannoma-presentation-of-a-case-and-review-of-literature
#7
Alejandro Jacob Madrid-Sánchez, Carlos Castillo-Rangel, Myriam Leticia Contreras-Ayala, Edgardo Ruiz-García, Ana Karen Castillo-Castro, Ricardo Ramírez-Aguilar
INTRODUCTION: Schwannomas are benign tumours that are relatively common in the head, however the involvement of the sinunasal region is rare and there are only 5 cases reported in the maxilla in current literature, representing less than 1% of bone tumours. CLINICAL CASE: We report the case of a woman with a right maxillary schwannoma who underwent a complete resection of the lesion. Emphasis is placed on the rarity of the lesion in terms of its location and includes a review of clinical behaviour, diagnosis and current treatment options...
December 30, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28005811/the-role-of-percutaneous-radiofrequency-thermocoagulation-for-persistent-or-recurrent-trigeminal-neuralgia-after-surgery
#8
Pengfei Liu, Wenxiang Zhong, Chenlong Liao, Min Yang, Wenchuan Zhang
Therapeutic strategy is controversial and not yet uniform for patients with trigeminal neuralgia (TN) and persistent or recurrent facial pain after microvascular decompression, percutaneous radiofrequency thermocoagulation (PRT), or Gamma Knife surgery. The outcomes and risks of PRT for these patients are not clearly understood. The authors performed a retrospective study of 84 patients with persistent or recurrent TN after surgery who then underwent PRT between 2007 and 2013. Data were obtained with chart review and telephone interviews...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005784/angular-relationship-between-the-foramen-ovale-and-the-trigeminal-impression-percutaneous-cannulation-trajectories-for-trigeminal-neuralgia
#9
Matthew J Zdilla, Scott A Hatfield, Kelsey R Mangus
The debilitating pain of trigeminal neuralgia often necessitates neurosurgical intervention via percutaneous transovale cannulation. While most percutaneous treatments of trigeminal neuralgia are successful, severe adverse events resulting from failure to properly cannulate the foramen ovale (FO) have been reported. With regard to specific targeting of particular trigeminal divisions (ie, V1, V2, V3, and combinations thereof), operative techniques have been described; however, these descriptions have not included specific angulation data...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27997548/using-diffusion-tensor-imaging-to-evaluate-microstructural-changes-and-outcomes-after-radiofrequency-rhizotomy-of-trigeminal-nerves-in-patients-with-trigeminal-neuralgia
#10
Shu-Tian Chen, Jen-Tsung Yang, Mei-Yu Yeh, Hsu-Huei Weng, Chih-Feng Chen, Yuan-Hsiung Tsai
Trigeminal neuralgia is characterized by facial pain that may be sudden, intense, and recurrent. Our aim was to investigate microstructural tissue changes of the trigeminal nerve in patients with trigeminal neuralgia resulting from neurovascular compression by diffusion tensor imaging, and to test the predictive value of diffusion tensor imaging for determining outcomes after radiofrequency rhizotomy. Forty-three patients with trigeminal neuralgia were recruited, and diffusion tensor imaging was performed before radiofrequency rhizotomy...
2016: PloS One
https://www.readbyqxmd.com/read/27996187/gasserian-ganglion-and-retrobulbar-nerve-block-in-the-treatment-of-ophthalmic-postherpetic-neuralgia-a-case-report
#11
Jie Huang, Ni Zhongge, Philip Finch
OBJECTIVES: Varicella-zoster virus reactivation can cause permanent histological changes in the central and peripheral nervous system. Neural inflammatory changes or damage to the dorsal root ganglia sensory nerve fibers during reactivation can lead to postherpetic neuralgia (PHN). For PHN of the first division of the fifth cranial nerve (ophthalmic division of the trigeminal ganglion), there is evidence of inflammatory change in the ganglion and adjacent ocular neural structures. First division trigeminal nerve PHN can prove to be difficult and sometimes even impossible to manage despite the use of a wide range of conservative measures, including anticonvulsant and antidepressant medication...
December 20, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27990312/ultra-extended-euthermic-pulsed-radiofrequency-for-the-treatment-of-ophthalmic-neuralgia-a-case-report-with-elaboration-of-a-new-technique
#12
Mohinish G Bhatjiwale, Mrudul M Bhatjiwale, Ami Bhagat
BACKGROUND: Pulsed radiofrequency although present for many years has been used little compared to ablative procedures for pain relief. Its use in trigeminal neuralgia is sparse and unreported in the ophthalmic division, where the possibility of sensory loss can lead to high morbidity. We wished to explore the potential of this reportedly safe modality for a prolonged duration in a highly sensitive anatomic neural location, however, in a very secure, structured, and staged manner. CASE DESCRIPTION: A patient suffering from ophthalmic division (V1) medically uncontrolled neuralgia with a preoperative visual analog scale (VAS) score of 9/10 was subjected to a percutaneous pain relief procedure...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27930513/percutaneous-trigeminal-ganglion-radiofrequency-thermocoagulation-alleviates-anxiety-and-depression-disorders-in-patients-with-classic-trigeminal-neuralgia-a-cohort-study
#13
YuanZhang Tang, Ling Ma, Na Li, Yuna Guo, Liqiang Yang, Baishan Wu, Jianning Yue, Qi Wang, Jingjie Liu, Jia-Xiang Ni
Trigeminal neuralgia (TN) is a neurological condition that presents as excruciating facial pain. Depression and anxiety are commonly associated with TN; however, anxiety and depression disorders in patients with TN and the effects of the various therapeutic strategies for TN on these disorders are not well studied.To evaluate depression and anxiety in patients with trigeminal neuralgia (TN), identify factors that predict their occurrence and study the effect of the percutaneous trigeminal ganglion radiofrequency thermocoagulation (PRT) procedure for alleviating pain on depression and anxiety...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27925184/a-case-report-about-cluster-tic-syndrome-due-to-venous-compression-of-the-trigeminal-nerve
#14
Ilse de Coo, J Marc C van Dijk, Jan D M Metzemaekers, Joost Haan
BACKGROUND: The term "cluster-tic syndrome" is used for the rare ipsilateral co-occurrence of attacks of cluster headache and trigeminal neuralgia. Medical treatment should combine treatment for cluster headache and trigeminal neuralgia, but is very often unsatisfactory. CASE: Here, we describe a 41-year-old woman diagnosed with cluster-tic syndrome who underwent microvascular decompression of the trigeminal nerve, primarily aimed at the "trigeminal neuralgia" part of her pain syndrome...
December 7, 2016: Headache
https://www.readbyqxmd.com/read/27919615/anatomical-study-of-the-superficial-temporal-branches-of-the-auriculotemporal-nerve-application-to-surgery-and-other-invasive-treatments-to-the-temporal-region
#15
Joe Iwanaga, Koichi Watanabe, Tsuyoshi Saga, Christian Fisahn, Rod J Oskouian, R Shane Tubbs
BACKGROUND AND AIM: The auriculotemporal nerve (ATN) is one of the branches of the mandibular division of the trigeminal nerve, which gives rise to many branches to the retromandibular and temporal regions. Of these, the superficial temporal branch can occasionally be the cause of migraine headaches and auriculotemporal neuralgia. The purpose of this study was to elucidate the anatomy of the superficial temporal branch, which has never been described in detail. METHODS: A total of 14 sides of cadaveric heads were used for this study...
November 11, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27911239/microvascular-decompression-of-the-cochleovestibular-nerve-for-treatment-of-tinnitus-and-vertigo-a-systematic-review-and-meta-analysis-of-individual-patient-data
#16
Minke J C van den Berge, J Marc C van Dijk, Iris A Posthumus, Nynke Smidt, Pim van Dijk, Rolien H Free
OBJECTIVE Microvascular decompression (MVD) is regarded as a valid treatment modality in neurovascular conflicts (NVCs) causing, for example, trigeminal neuralgia and hemifacial spasms. An NVC of the cochleovestibular nerve might cause tinnitus and/or vertigo; however, general acceptance of MVD for this indication is lacking. The aim of this study was to investigate the effectiveness, safety, and prognostic factors for success of MVD of the cochleovestibular nerve. METHODS A systematic review and meta-analysis of individual patient data (IPD) were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Individual Patient Data (PRISMA-IPD) guidelines...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27903196/the-impact-of-cobalt-60-source-age-on-biologically-effective-dose-in-high-dose-functional-gamma-knife-radiosurgery
#17
Benjamin H Kann, James B Yu, John M Stahl, James E Bond, Christopher Loiselle, Veronica L Chiang, Ranjit S Bindra, Jason L Gerrard, David J Carlson
OBJECTIVE Functional Gamma Knife radiosurgery (GKRS) procedures have been increasingly used for treating patients with tremor, trigeminal neuralgia (TN), and refractory obsessive-compulsive disorder. Although its rates of toxicity are low, GKRS has been associated with some, if low, risks for serious sequelae, including hemiparesis and even death. Anecdotal reports have suggested that even with a standardized prescription dose, rates of functional GKRS toxicity increase after replacement of an old cobalt-60 source with a new source...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27901275/peripheral-nerve-blocks-for-the-treatment-of-headache-in-older-adults-a-retrospective-study
#18
Jacob R Hascalovici, Matthew S Robbins
OBJECTIVE: The objective of this study is to provide demographical and clinical descriptions of patients age 65 years old and older who were treated with peripheral nerve blocks (PNBs) at our institution and evaluate the safety and efficacy of this treatment. BACKGROUND: Headache disorders are common, disabling chronic neurological diseases that often persist with advancing age. Geriatric headache management poses unique therapeutic challenges because of considerations of comorbidity, drug interactions, and adverse effects...
January 2017: Headache
https://www.readbyqxmd.com/read/27890181/imaging-of-vascular-compression-syndromes
#19
REVIEW
Joseph H Donahue, David A Ornan, Sugoto Mukherjee
Trigeminal neuralgia, hemifacial spasm, vestibulocochlear neuralgia and glossopharyngeal neuralgia represent the most common neurovascular compression syndromes. Repeated vascular pulsations at the vulnerable transitional zone of the individual cranial nerves lead to focal axonal injury and demyelination. High-resolution 3-D T2-weighted MR imaging is essential in detecting and mapping neurovascular compression for directed therapy. Knowledge of the specific nerve root exit, the transitional zones, and the adjacent vasculature is critical in proper management...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27885344/drug-induced-hypersensitivity-syndrome-caused-by-carbamazepine-used-for-the-treatment-of-trigeminal-neuralgia
#20
Yuko Ono, Tsuyoshi Shimo, Yoshinori Shirafuji, Toshihisa Hamada, Masanori Masui, Kyoichi Obata, Mayumi Yao, Koji Kishimoto, Akira Sasaki
An 88-year-old man was diagnosed with trigeminal neuralgia, and treatment of carbamazepine 200 mg/day was initiated. About 6 weeks later, the patient developed a skin rash accompanied by fever. He was admitted to hospital and diagnosed with drug-induced hypersensitivity syndrome (DIHS) caused by carbamazepine. Oral carbamazepine treatment was stopped, but blood tests showed acute liver and acute renal failure. Drug-induced lymphocyte stimulation test (DLST) for carbamazepine, human herpes virus-6 (HHV-6) IgG, and CMV-HRP were negative...
2016: Case Reports in Dentistry
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