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Eva K Masel, Gudrun Kreye
There is robust data that palliative care is prolonging life while there are still prejudices towards this discipline that have to be demystified. Patients, relatives and caregivers benefit from the concept of early integration of palliative care and therefore, palliative care should not be mainly regarded as end-of-life care.
2018: Memo
Samantha Hurst, Meghan Maiya, Danielle Casteel, Andrew J Sarkin, Salvatore Libretto, A Rani Elwy, Crystal L Park, Erik J Groessl
OBJECTIVE: Millions of military personnel and veterans live with chronic mental and physical health conditions that often do not respond well to pharmacological treatments. Serious side effects and lack of treatment response have led to widespread efforts to study and promote non-pharmacological and behavioral health treatments for many chronic health conditions. Yoga is an increasingly popular mind-body intervention that has growing research support for its efficacy and safety. Our objective was to explore the attitudes, perspectives, and preferences of military personnel and veterans toward yoga as a therapeutic modality, thus providing needed information for designing and promoting yoga interventions for this population...
October 2018: Complementary Therapies in Medicine
Gouri Mukerjee, Andrea Huston, Boyko Kabakchiev, Micheline Piquette-Miller, Ron van Schaik, Ruslan Dorfman
Pharmacogenomic (PGx) testing is gaining recognition from physicians, pharmacists and patients as a tool for evidence-based medication management. However, seemingly similar PGx testing panels (and PGx-based decision support tools) can diverge in their technological specifications, as well as the genetic factors that determine test specificity and sensitivity, and hence offer different values for users. Reluctance to embrace PGx testing is often the result of unfamiliarity with PGx technology, a lack of knowledge about the availability of curated guidelines/evidence for drug dosing recommendations, and an absence of wide-spread institutional implementation efforts and educational support...
2018: NPJ Genomic Medicine
A H Fine
Over the past 20 years, a great deal of attention has been paid to the psychological and physiological impact that animals have on the lives of people with disabilities. The focus of this paper is to demystify the mechanisms that are affected as a consequence of these interactions as well as to describe the value of various types of therapeutic working animals. For human-animal interactions to become more legitimised, more rigorous empirical research needs to be undertaken to demonstrate the value of such interactions as well as the need for changes in the public policy impacting them...
April 2018: Revue Scientifique et Technique
Dana C Beck, Michelle L Munro-Kramer, Jody R Lori
This review integrates evidence on community mobilisation (CM) for maternal and child health in sub-Saharan Africa (SSA) to identify the impact on empowerment. For the purposes of this review we use the following definition of CM: 'a capacity-building process through which community members, groups or organizations plan, carry out and evaluate activities on a participatory and sustained basis to improve their health and other conditions, either on their own initiative or stimulated by others', [Howard-Grabman, L...
September 5, 2018: Global Public Health
Jennifer Sanchez-Davies
Literature can offer a wealth of information about epilepsy: from complex narratives to children's picture books, it can help broaden people's understanding, show what it is like to live with epilepsy and provide a medium to which people with epilepsy (PWE) can relate. The latter being particularly important in such cases where seizure experiences are highly subjective, such as those associated with 'focal seizures', a common seizure type, which are known for their variable and hard-to-describe symptoms, causing complications with diagnosis as many of the symptoms overlap with those of other psychological health conditions...
September 3, 2018: Medical Humanities
Anindya Das, Urvashi Rautela
The issue of culture in Indian psychiatry has endured increasing neglect with the burgeoning biological paradigm. This viewpoint debates and demystifies the connotation of "culture" in mainstream psychiatry. As a template to infer dominant thinking in mainstream psychiatry about culture, DLN Murty Rao Oration in 2011, "Indianizing Psychiatry - Is there a case enough?" by Avasthi (2011) (published in the Indian Journal of Psychiatry) has been used. Engaging a broad interdisciplinary view helps unravel the inherent biases in psychiatry and opens up space for analysis of the Indian psyche from a different philosophic tradition and ways of researching it...
April 2018: Indian Journal of Psychiatry
Hui Ouyang, Tao Bo, Zhengxiang Zhang, Xinqiu Guo, Mingzhen He, Junmao Li, Shilin Yang, Xin Ma, Yulin Feng
RATIONALE: In the medicine and drug development, molecular modelling is an important tool. It is attractive to develop a platform connecting the theoretical structure modelling and the results from experimental measurement. In addition, separation and structure analysis of bioactive constituent isomers are still challenging. METHODS: Drift tube ion mobility (IM)-mass spectrometry (MS) provides the experimental collision cross section (CCS) which contains the structural information...
August 27, 2018: Rapid Communications in Mass Spectrometry: RCM
Steven Lai, Ashika Jain, Jessica Mason, Andrew Grock
No abstract text is available yet for this article.
September 2018: Annals of Emergency Medicine
Adouda Adjiri
BACKGROUND: Cancer is a defiant disease which cure is still far from being attained besides the colossal efforts and financial means deployed towards that end. The continuing setbacks encountered with today's arsenal of anti-cancer drugs and cancer therapy modalities; show the need for a radical approach in order to get to the root of the problem. And getting to the root of cancer initiation and development leads us to challenge the present dogmas surrounding the pathogenesis of this disease...
August 17, 2018: BMC Cancer
Selina Y L Holbrook, Sylvie Garneau-Tsodikova
Medicinal chemistry is a scientific discipline that has progressed rapidly over the last few decades. Facilitated by the technological advancement, the early understanding of medicinal chemistry as "synthesizing bioactive molecules" has become the connecting bridge of a variety of related scientific disciplines. This opinion article will guide you through a brief evolution of this discipline and discuss what medicinal chemistry has evolved to be in this era.
September 1, 2017: MedChemComm
Agnes Moors, Maja Fischer
The paper sketches the historical development from emotion as a mysterious entity and the source of maladaptive behaviour, to emotion as a collection of ingredients and the source of also adaptive behaviour. We argue, however, that the underlying mechanism proposed to take care of this adaptive behaviour is not entirely up for its task. We outline an alternative view that explains so-called emotional behaviour with the same mechanism as non-emotional behaviour, but that is at the same time more likely to produce adaptive behaviour...
August 13, 2018: Cognition & Emotion
Juan M Bolivar, Donya Valikhani, Bernd Nidetzky
Continuous (flow) reactors have drawn a wave of renewed interest in biocatalysis. Many studies find that the flow reactor offers enhanced conversion efficiency. What the reported reaction intensification actually consists in, however, often remains obscure. Here, a canonical microreactor design for heterogeneously catalyzed continuous biotransformations, featuring flow microchannels that contain the enzyme immobilized on their wall surface are examined. Glycosylations by sucrose phosphorylase are used to assess the potential for reaction intensification due to microscale effects...
August 9, 2018: Biotechnology Journal
Paulo Sérgio da Silva, Nébia Maria Almeida de Figueiredo
OBJECTIVE: to reflect on the body of the nursing professor in the subjectivity discourse. METHOD: this is a reflective essay on the theoretical and practical reverberations of the nursing professor's body based on the Deleuzoguattarian discourse. RESULTS: in the theoretical framework, the body of the nursing professor was considered as a producer of subjectivities and understood without organs, surrounded by strengths, desires, and affections...
2018: Revista Brasileira de Enfermagem
Laura Bishop
Music performance is inherently social. Most music is performed in groups, and even soloists are subject to influence from a (real or imagined) audience. It is also inherently creative. Performers are called upon to interpret notated music, improvise new musical material, adapt to unexpected playing conditions, and accommodate technical errors. The focus of this paper is how creativity is distributed across members of a music ensemble as they perform these tasks. Some aspects of ensemble performance have been investigated extensively in recent years as part of the broader literature on joint action (e...
2018: Frontiers in Psychology
Fiona Atim, Teddy Nagaddya, Florence Nakaggwa, Mary Gorrethy N-Mboowa, Peter Kirabira, John Charles Okiria
BACKGROUND: Canine Bud Extraction (CBE) is a process of removing or gouging children's healthy canine tooth buds embedded underneath the gum using traditional unsterilized tools. The practice of CBE commonly known as false teeth removal continues to be an adopted cultural intervention of choice, in the prevention of morbidity and mortality from common childhood illnesses. However, it is a practice against the rights of the children with serious consequences. While CBE is associated with the perceived myth of curative gains, the agony emanating from the cultural practice exposes children to ill-health conditions such as dehydration, malnutrition, blood-borne diseases like HIV/AIDs, septicemia, fever and death...
August 7, 2018: BMC Oral Health
David Ayobami Adewole
Health insurance scheme is relatively new in many low to middle income countries. Awareness about and knowledge of the scheme is poor among potential beneficiaries. There are some misconceptions associated with health insurance, which contributes to its low acceptance in affected nations. The aim of this work is to present an information-education and communication concept that will serve as a social marketing tool that could enhance peoples' understanding of the modus operandi of health insurance scheme, and as well as to demystify superstitious belief associated with it...
May 21, 2018: Journal of Public Health in Africa
Raju Vaishya
No abstract text is available yet for this article.
July 2018: Indian Journal of Orthopaedics
Mohamed Bekheit, Irfan Ahmed
No abstract text is available yet for this article.
July 30, 2018: Annals of Surgery
David G Whitten, Yanli Tang, Zhijun Zhou, Jianzhong Yang, Ying Wang, Eric H Hill, Harry C Pappas, Patrick L Donabedian, Eva Y Chi
In this retrospective, we first reviewed the synthesis of the oligo(phenylene-ethynylene) electrolytes (OPEs) we created in the past 10 years. Since the general antimicrobial activity of these OPEs had been reported in our previous account in Langmuir, we are focusing only on the unusual spectroscopic and photophysical properties of these OPEs and their complexes with anionic scaffolds and detergents in this Feature Article. We applied classical all-atom MD simulations to study the hydrogen bonding environment in the water surrounding the OPEs with and without detergents present...
August 14, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
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