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https://www.readbyqxmd.com/read/29228870/augmented-photocatalytic-antibacterial-and-antifungal-activity-of-prunosynthetic-silver-nanoparticles
#1
Shaan Bibi Jaffri, Khuram Shahzad Ahmad
The present study has demystified the first and single step prunosynthesis of the spherical silver nanoparticles (AgNPs) from aqueous fruit extract of angiospermic plant, Prunus cerasifera, which has remarkable fusion of reducing cum stabilizing bioactive components (phenols, anthocyanins, carotenoids, flavonoids, organic acids, tannins and vitamins). Highly stable prunosynthetic AgNPs with 2.04 nm average crystallite size were synthesized in dark and in sunlight at optimized condition of temperature, time and P...
December 11, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29200478/submission-to-publication-demystified-a-guide-for-authors
#2
EDITORIAL
Ish Kumar Dhammi, Rehan Ul Haq
No abstract text is available yet for this article.
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29182323/demystifying-p2y1-receptor-ligand-recognition-through-docking-and-molecular-dynamics-analyses
#3
Antonella Ciancetta, Robert D O'Connor, Silvia Paoletta, Kenneth A Jacobson
We performed a molecular modeling analysis of 100 nucleotide-like bisphosphates and 46 non-nucleotide arylurea derivatives previously reported as P2Y1R binders using the recently solved hP2Y1R structures. We initially docked the compounds at the X-ray structures and identified the binding modes of representative compounds highlighting key patterns in the structure-activity relationship (SAR). We subsequently subjected receptor complexes with selected key agonists (2MeSADP and MRS2268) and antagonists (MRS2500 and BPTU) to membrane molecular dynamics (MD) simulations (at least 200 ns run in triplicate, simulation time 0...
November 28, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29159675/diffusion-weighted-imaging-demystified-the-technique-and-potential-clinical-applications-for-soft-tissue-imaging
#4
REVIEW
Shivani Ahlawat, Laura M Fayad
Diffusion-weighted imaging (DWI) is a fast, non-contrast technique that is readily available and easy to integrate into an existing imaging protocol. DWI with apparent diffusion coefficient (ADC) mapping offers a quantitative metric for soft tissue evaluation and provides information regarding the cellularity of a region of interest. There are several available methods of performing DWI, and artifacts and pitfalls must be considered when interpreting DWI studies. This review article will review the various techniques of DWI acquisition and utility of qualitative as well as quantitative methods of image interpretation, with emphasis on optimal methods for ADC measurement...
November 20, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29074394/n-6-adenine-dna-methylation-demystified-in-eukaryotic-genome-from-biology-to-pathology
#5
REVIEW
Nidarshana Chaturvedi Parashar, Gaurav Parashar, Harsh Nayyar, Rajat Sandhir
N(6)-methyl-2'-deoxyadenosine (m6dA) is a well characterized DNA modification in prokaryotes. Its existence in eukaryotic DNA remained doubtful until recently. Evidence suggests that the m6dA levels decrease with the increasing complexity of eukaryotic genomes. Analysis of m6dA levels in genome of lower eukaryotes reveals its role in gene regulation, nucleosome positioning and early development. In higher eukaryotes m6dA is enriched in nongenic region compared to genic region, preferentially in chromosome X and 13 suggesting a chromosome bias...
October 23, 2017: Biochimie
https://www.readbyqxmd.com/read/29072121/colonic-stasis-and-chronic-constipation-demystifying-proposed-risk-factors-for-colon-polyp-formation-in-a-spinal-cord-injury-veteran-population
#6
Jason Colizzo, Jonathan Keshishian, Ambuj Kumar, Gitanjali Vidyarthi, Donald Amodeo
BACKGROUND AND AIMS: Patients with spinal cord injury (SCI) suffer significant morbidity from neurogenic bowel. Chronic constipation has long-been a proposed risk factor for polyp development. We performed a retrospective cohort study in veterans with SCI to assess polyp presence in the setting of colonic stasis. METHODS: All consecutive patients at the James A. Haley Veterans Affairs Hospital with SCI and neurogenic bowel who completed screening colonoscopy between January 1, 2004 to June 30, 2013 were included...
October 26, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29067928/multi-organ-igg4-related-disease-demystifying-the-diagnostic-enigma
#7
S Bhardwaj, S Goyal, A K Yadav, A Goyal
IgG4-related disease (IgG4-RD) is a multisystemic mass forming immune-mediated disease entity, commonly creating confusion and diagnostic challenges. We present a case of a 25-year-old female who presented with bilateral orbital masses, lymphadenopathy, paraspinal and renal masses, which clinicoradiologically simulated lymphoma. The lymph node biopsy revealed interfollicular sheets of plasma cells creating confusion with Castleman's disease and marginal zone lymphoma. The orbital biopsy revealed ductular destruction, periductular plasma cells, and fibrosis, mimicking Sjogren's syndrome and Castleman's disease...
October 23, 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/29066449/effect-of-vitamin-d-supplementation-on-arterial-stiffness-and-central-blood-pressure-indexes-demystifying-the-evidence
#8
EDITORIAL
Pankaj Arora, Thomas J Wang
No abstract text is available yet for this article.
October 24, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29052731/demystifying-neurosarcoidosis-and-informing-prognosis
#9
Jeffrey M Gelfand
No abstract text is available yet for this article.
November 1, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29040894/demystifying-endoscopic-retrograde-cholangiopancreatography-ercp-during-pregnancy
#10
REVIEW
Vítor Magno-Pereira, Pedro Moutinho-Ribeiro, Guilherme Macedo
BACKGROUND: For many years, ERCP was avoided in pregnancy given the concerns regarding the adverse effects that, with special focus on radiation, could occur in the developing fetus. However, the postponement or rejection of ERCP in pregnant women, may lead to a higher risk for mother and fetus, especially when the indication is unequivocal, namely cholangitis, biliary pancreatitis and symptomatic choledocholithiasis. SUMMARY AND KEY MESSAGES: This review aims to summarize the scarce literature on the subject in order to plan ERCP in pregnancy with the highest safety...
December 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29040397/demystifying-the-july-effect-in-plastic-surgery-a-multi-institutional-study
#11
Jordan T Blough, Sumanas W Jordan, Gildasio S De Oliveira, Michael M Vu, John Y S Kim
Background: The "July Effect" refers to a theoretical increase in complications that may occur with the influx of inexperienced interns and residents at the beginning of each academic year in July. Objectives: We endeavored to determine if a July Effect occurs in plastic surgery. Methods: Plastic surgery procedures were isolated from the National Surgical Quality Improvement Program registry. Cases involving residents were grouped as either having occurred within the first academic quarter (AQ1) or remaining year (AQ2-4)...
September 15, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29040371/commentary-on-demystifying-the-july-effect-in-plastic-surgery-a-multi-institutional-study
#12
Steven J Kasten, Paul S Cederna
No abstract text is available yet for this article.
September 16, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29037656/demystifying-shoulder-pain-with-electrodiagnosis-and-musculoskeletal-ultrasound-imaging
#13
EDITORIAL
Dimitrios Kostopoulos, Mohini Rawat
No abstract text is available yet for this article.
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29029663/demystifying-probiotics-use-in-the-elderly
#14
Caren McHenry Martin, Gianna Bryan
Pharmacists and other health care professionals can be perplexed by the growing body of literature regarding the use of probiotics for a variety of symptoms and conditions and by an increasing number of probiotic products available to consumers. Understanding the functions of the intestinal microbiome, the possible mechanisms of actions of probiotics, the research supporting or refuting probiotic use, and criteria for selecting a probiotic product is essential to making a rational recommendation for patients...
August 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28983203/enhancing-the-research-and-publication-efforts-of-health-sciences-librarians-via-an-academic-writing-retreat
#15
John W Bullion, Stewart M Brower
BACKGROUND: This case study describes the South Central Chapter of the Medical Library Association (SCC/MLA) initiative to develop an academic writing retreat for members who sought the necessary time and support to advance their research projects toward publication. CASE PRESENTATION: SCC/MLA staged a dedicated writing retreat to coincide with the organization's 2012, 2013, and 2014 annual meetings. Each cohort met over two days to write and to workshop their peers' manuscripts...
October 2017: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/28961982/rapid-evolution-of-genes-involved-in-learning-and-energy-metabolism-for-domestication-of-the-laboratory-rat
#16
Lin Zeng, Chen Ming, Yan Li, Ling-Yan Su, Yan-Hua Su, Newton O Otecko, He-Qun Liu, Ming-Shan Wang, Yong-Gang Yao, Hai-Peng Li, Dong-Dong Wu, Ya-Ping Zhang
The laboratory rat, widely used in biomedical research, is domesticated from wild brown rat. The origin and genetic mechanism underlying domestication of the laboratory rat remain largely elusive. In the present study, large scale genomes supported a single origin for the laboratory rat, possibly from a sister group to wild rats from Europe/Africa/Middle East. Genomic and transcriptomic analyses uncovered many artificially selected genes (e.g. FOXP2, B3GAT1, and CLOCK) involved in the nervous system. These genes associate with learning ability and regulation of circadian rhythm, which likely enabled the successful domestication of the laboratory rat...
September 12, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28938360/implant-porosity-and-the-foreign-body-response
#17
Sumanas W Jordan, Jennifer E Fligor, Lindsay E Janes, Gregory A Dumanian
The biocompatibility of prosthetic mesh is dependent on a number of physicochemical properties that ultimately incite an optimal foreign body response (FBR). The magnitude and character of the FBR directly affect the clinical success of the hernia repair, with too little scar resulting in bulge or hernia recurrence and too much scar causing mesh wrinkling and pain. Moreover, it is important to consider the effect of a sustained FBR and scar remodeling on the combined strength of the mesh-tissue construct over time...
September 15, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28886352/benchmarking-an-effective-tool-to-demystify-the-academic-career
#18
Gino Inverso, John R Zuniga, Neeraj H Panchal
No abstract text is available yet for this article.
August 12, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28873882/not-just-the-right-to-a-wheelchair-but-the-right-wheelchair-improving-brazilian-wheelchair-service-delivery
#19
Tulio Maximo, Laurence Clift
This paper discusses the barriers encountered before and after the implementation of good practice in the delivery of wheelchair provision services in Belo Horizonte city, Brazil. The results demystify some participants' initial idea that using an assessment form might take significantly more time. Major barriers to implementation had regard to the assessment of pressure sores and a lack of wheelchair suppliers.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28872869/demystifying-multitask-deep-neural-networks-for-quantitative-structure-activity-relationships
#20
Yuting Xu, Junshui Ma, Andy Liaw, Robert P Sheridan, Vladimir Svetnik
Deep neural networks (DNNs) are complex computational models that have found great success in many artificial intelligence applications, such as computer vision1,2 and natural language processing.3,4 In the past four years, DNNs have also generated promising results for quantitative structure-activity relationship (QSAR) tasks.5,6 Previous work showed that DNNs can routinely make better predictions than traditional methods, such as random forests, on a diverse collection of QSAR data sets. It was also found that multitask DNN models-those trained on and predicting multiple QSAR properties simultaneously-outperform DNNs trained separately on the individual data sets in many, but not all, tasks...
October 23, 2017: Journal of Chemical Information and Modeling
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