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https://www.readbyqxmd.com/read/29340805/cardiorespiratory-fitness-and-cardiovascular-disease-prevention-an-update
#1
REVIEW
Mouaz H Al-Mallah, Sherif Sakr, Ada Al-Qunaibet
PURPOSE OF REVIEW: Cardiovascular diseases account for nearly one third of all deaths globally. Improving exercise capacity and cardiorespiratory fitness (CRF) has been an important target to reduce cardiovascular events. In addition, the American Heart Association defined decreased physical activity as the fourth risk factor for coronary artery disease. Multiple large cohort studies have evaluated the impact of CRF on outcomes. In this review, we will discuss the role of CRF in reducing cardiovascular morbidity and mortality...
January 16, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29340149/acute-kidney-injury-due-to-multiple-hymenoptera-stings-a-clinicopathological-study
#2
Sanjay Vikrant, Anupam Parashar
Background: Acute kidney injury (AKI) after multiple Hymenoptera stings is well known but still a rare phenomenon. Methods: We conducted a retrospective study of the clinicopathological spectrum of AKI due to multiple Hymenoptera stings over 13 years (July 2003-June 2016). Results: A total of 35 patients were diagnosed with AKI due to multiple Hymenoptera stings. The mean age of the patients was 44.7 ± 17.4 years and the majority (60%) were men...
August 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29340036/the-association-between-elevated-fasting-plasma-glucose-levels-and-carotid-intima-media-thickness-in-non-diabetic-adults-a-population-based-cross-sectional-study
#3
Yalin Guan, Changshen Yu, Min Shi, Jingxian Ni, Yanan Wu, Hongfei Gu, Lingling Bai, Jie Liu, Jun Tu, Jinghua Wang, Xianjia Ning
We assessed the association between the mean carotid intima-media thickness (CIMT) and fasting plasma glucose (FPG) levels in a low-income population in rural China. Adults aged ≥45 years without a history of diabetes, stroke, or cardiovascular disease were recruited. All participants were categorized into four groups according to FPG level. A total of 3509 participants were analyzed in this study. In the univariate analysis, sex, age, education level, hypertension, central obesity, current smoking, alcohol consumption, and higher levels of FPG, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were associated with mean CIMT and frequency of increased CIMT...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29339206/objective-sleep-measures-in-subacute-stroke-inpatients-associated-with-levels-and-improvements-in-activities-of-daily-living
#4
Ren-Jing Huang, Ching-Hsiang Lai, Shin-Da Lee, Fang-Yu Pai, Shen-Wen Chang, Ai-Hui Chung, Yi-Fang Chang, Hua Ting
OBJECTIVE: To investigate whether objective polysomnographic measures of prevalent sleep problems such as sleep-disordered-breathing (SDB) and insomnia are associated with activities of daily living levels in inpatients at rehabilitation units DESIGN: Retrospective and observational study SETTING: Single rehabilitation center PARTICIPANTS: One hundred twenty-three enrolled subacute stroke inpatients (61.6 ± 13.1 years; 23.8 ± 3.4 kg/m2; 33% female; 90.5 ± 36.7 days post-stroke) underwent a one-night polysomnography study and one-month-long inpatient rehabilitation program...
January 12, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29337636/new-onset-cardiovascular-morbidity-in-older-adults-with-stage-i-to-iii-colorectal-cancer
#5
Kelly M Kenzik, Courtney Balentine, Joshua Richman, Meredith Kilgore, Smita Bhatia, Grant R Williams
Purpose We sought to determine the long-term risk of cardiovascular disease (CVD)-stroke and myocardial infarction-and congestive heart failure (CHF) in older patients with colorectal cancer, as well as to understand the roles that preexisting comorbidities and cancer therapy play in increasing this risk. Patients and Methods We evaluated individuals from the SEER-Medicare database with incident stage I to III colorectal cancer at age older than 65 years between January 1, 2000, and December 31, 2011 (n = 72,408) and compared these patients with a matched cohort of Medicare patients without cancer (n = 72,408)...
January 16, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29336359/white-matter-lesions-predict-recurrent-vascular-events-in-patients-with-transient-ischemic-attacks
#6
Xiao-Mei Ren, Shu-Wei Qiu, Ren-Yuan Liu, Wen-Bo Wu, Yun Xu, Hong Zhou
BACKGROUND: White matter lesions (WMLs) are common findings in brain magnetic resonance imaging (MRI) and are strongly associated with stroke incidence, recurrence, and prognosis. However, the relationship between WMLs and transient ischemic attacks (TIAs) is not well established. This study aimed to determine the clinical significance of WMLs in patients with TIA. METHODS: A total of 181 consecutive inpatients with first-ever TIA were enrolled. Brain MRIs within 2 days of symptom onset were used to measure WML volumes...
January 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29336246/the-role-of-colchicine-in-the-prevention-of-cerebrovascular-ischemia
#7
Georgios Tsivgoulis, Aristeidis H Katsanos, Georgios Giannopoulos, Vasiliki Panagopoulou, Dalius Jatuzis, Robin Lemnens, Spyridon Deftereos, Peter J Kelly
INTRODUCTION: Despite the proven efficacy of anti-thrombotic, lipid-lowering, anti-hypertensive therapies and lifestyle modification changes for secondary ischemic stroke prevention, the risk of recurrent stroke, coronary events and vascular death remains substantial even for patients treated with high rates of established secondary preventive medications. METHODS: In the present review, we summarize available literature data on the association between systemic inflammation and symptomatic atherosclerosis including recurrent cerebral ischemia...
January 15, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29334713/-prevalence-and-influential-factors-of-stroke-in-jiangxi-province-in-2014
#8
W Zhou, B Zhang, X Huang, C J You, B M Zhan, R Q Yang, Y F Dong, J X Li, P Li, K Hong, Y Q Wu, Q H Wu, H Su, H H Bao, X S Cheng
Objective: To discuss the prevalence and influential factors of stroke among population in Jiangxi Province. Methods: Four cities in urban areas and four counties in rural areas were selected firstly, in which two districts or townships were selected; and then three communities or villages were chosen from each district and township, respectively, using the simple random sampling (SRS) method. Finally 15 269 subjects aging 15 years old or above, living in Jiangxi Province ≥6 months were randomly selected to participate in this survey from November 2013 to August 2014...
January 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29334526/airborne-particulate-matter-human-exposure-health-effects
#9
Jonathan E Thompson
OBJECTIVE: Exposure to airborne particulate matter (PM) is estimated to cause millions of premature deaths annually. This work conveys known routes of exposure to PM and resultant health effects. METHODS: Review of available literature. RESULTS: Estimates for daily PM exposure are provided. Known mechanisms by which insoluble particles are transported and removed from the body are discussed. Biological effects of PM, including immune response, cytotoxicity, and mutagenicity are reported...
January 12, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29334333/are-people-at-high-risk-for-diabetes-visiting-health-facility-for-confirmation-of-diagnosis-a-population-based-study-from-rural-india
#10
Nikhil Srinivasapura Venkateshmurthy, Kathirvel Soundappan, Balaji Gummidi, Malipeddi Bhaskara Rao, Nikhil Tandon, K Srinath Reddy, Dorairaj Prabhakaran, Sailesh Mohan
BACKGROUND: India is witnessing a rising burden of type 2 diabetes mellitus. India's National Programme for Prevention and Control of Diabetes, Cancer, Cardiovascular diseases and Stroke recommends population-based screening and referral to primary health centre for diagnosis confirmation and treatment initiation. However, little is known about uptake of confirmatory tests among screen positives. OBJECTIVE: To estimate the uptake of confirmatory tests and identify the reasons for not undergoing confirmation by those at high risk for developing diabetes...
2018: Global Health Action
https://www.readbyqxmd.com/read/29334265/prevalence-and-covariates-of-uncontrolled-hypertension-in-ischemic-stroke-survivors-the-norwegian-stroke-in-the-young-study
#11
Åshild Oftedal, Eva Gerdts, Ulrike Waje-Andreassen, Annette Fromm, Halvor Naess, Anja Linde, Sahrai Saeed
PURPOSE: Hypertension is the most important modifiable risk factor for stroke. Few data are available on control of hypertension in younger ischemic stroke survivors. MATERIAL AND METHODS: We assessed clinic and ambulatory blood pressure (BP) measurements in 320 patients aged 15-60 years (mean 48 ± 10) included in the Norwegian Stroke in the Young Study during 3-months follow-up after the index stroke. Controlled hypertension was defined as ambulatory BP <130/80 mmHg...
January 15, 2018: Blood Pressure
https://www.readbyqxmd.com/read/29332678/relationship-of-sleep-pattern-and-snoring-with-chronic-disease-findings-from-a-nationwide-population-based-survey
#12
Fakir Md Yunus, Safayet Khan, Dipak K Mitra, Sabuj Kanti Mistry, Kaosar Afsana, Mahfuzar Rahman
OBJECTIVES: To investigate the association of total sleep time and presence or absence of snoring with chronic disease among the Bangladeshi adult population. DESIGN: Cross-sectional survey. SETTING: Urban and rural Bangladesh. PARTICIPANTS: A total of 12,338 men and women aged ≥35 years. MEASUREMENTS: Total sleep time was considered as the total hours of sleep in 24 hours. Furthermore, sleep time was categorized into <7, 7-9, and >9 hours according to National Sleep Foundation (2015) guidelines...
February 2018: Sleep Health
https://www.readbyqxmd.com/read/29331969/temporal-trends-in-antithrombotic-treatment-of-real-world-uk-patients-with-newly-diagnosed-atrial-fibrillation-findings-from-the-garfield-af-registry
#13
Patricia N Apenteng, Haiyan Gao, Fd Richard Hobbs, David A Fitzmaurice
OBJECTIVE: To investigate evolving patterns in antithrombotic treatment in UK patients with newly diagnosed non-valvular atrial fibrillation (AF). DESIGN: Prospective, multicentre, international registry. SETTING: 186 primary care practices in the UK. PARTICIPANTS: 3482 participants prospectively enrolled in four sequential cohorts (cohort 2 (C2) n=830, diagnosed September 2011 to April 2013; cohort 3 (C3) n=902, diagnosed April 2013 to June 2014; cohort 4 (C4) n=850, diagnosed July 2014 to June 2015; cohort 5 (C5) n=900, diagnosed June 2015 to July 2016)...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29330911/title-prognostic-significance-of-arterial-stiffness-and-osteoprotegerin-in-patients-with-stable-coronary-artery-disease
#14
Gerasimos Siasos, Evangelos Oikonomou, Konstantinos Maniatis, Georgios Georgiopoulos, Eleni Kokkou, Vasiliki Tsigkou, Marina Zaromitidou, Alexis Antonopoulos, Manolis Vavuranakis, Christodoulos Stefanadis, Athanasios G Papavassiliou, Dimitris Tousoulis
BACKGROUND: Arterial stiffness and vascular calcification significantly contribute to coronary atherosclerosis progression. The prognostic value of increased arterial stiffness and vascular calcification in subjects with stable coronary artery disease (CAD) after percutaneous coronary intervention(PCI) is currently under question. MATERIALS AND METHODS: We randomly enrolled 262 patients with stable CAD one month after successful PCI. Carotid femoral pulse wave velocity (PWV) was measured as a well-established index of central aortic stiffness...
January 13, 2018: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29330891/why-do-african-american-have-a-higher-risk-for-cerebral-disease
#15
Shigehiko Ogoh
Clinical and epidemiological studies have reported significant racial differences in cardiovascular (CVD) and metabolic disease including hypertension, stroke, atherosclerosis, and type II diabetes which is most prevalent in the African American population. This article is protected by copyright. All rights reserved.
January 12, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29330695/glucosuria-and-all-cause-mortality-among-general-screening-participants
#16
Kunitoshi Iseki, Tsuneo Konta, Koichi Asahi, Kunihiro Yamagata, Shouichi Fujimoto, Kazuhiko Tsuruya, Ichiei Narita, Masato Kasahara, Yugo Shibagaki, Toshiki Moriyama, Masahide Kondo, Chiho Iseki, Tsuyoshi Watanabe
BACKGROUND: Dipstick urine tests are used for general health screening in Japan, but how the test results (e.g., glucosuria) relate to mortality is unknown. METHODS: Subjects participated in a nationwide screening in 2008 in six districts in Japan. We identified those who might have died using the national database of death certificates from 2008 to 2012 (total registered ~ 6 million) and verified candidates with the regional National Health Insurance Agency and public health nurses...
January 12, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29330520/association-of-homocysteine-with-aysmptomatic-intracranial-and-extracranial-arterial-stenosis-in-hypertension-patients
#17
Yan Wang, Jin Zhang, Yuesheng Qian, Xiaofeng Tang, Huawei Ling, Kemin Chen, Yan Li, Pingjin Gao, Dingliang Zhu
Elevated plasma homocysteine (Hcy) is suggested as an independent risk factor for stroke. We aimed to investigate the association of Hcy concentration with intracranial atherosclerosis (ICAS) and extracranial AS (ECAS) in hypertensive patients without stroke in Chinese population and to explore modified effect of methylenetetrahydrofolate reductase (MTHFR) C677T on their relationship. The stenosis of intracranial and extracranial arteries were evaluated in a total of 929 subjects through computerized tomographic angiography (CTA) from aortic arch to the skull base...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330420/left-ventricular-hypertrophy-and-cognitive-function-a-systematic-review
#18
C Restrepo, S K Patel, V Rethnam, E Werden, J Ramchand, L Churilov, L M Burrell, A Brodtmann
Cognitive impairment is common in patients with hypertension. Left ventricular hypertrophy (LVH) is recognised as a marker of hypertension-related organ damage and is a strong predictor of coronary artery disease, heart failure and stroke. There is evidence that LVH is independently associated with cognitive impairment, even after adjustment for the presence of hypertension. We conducted a systematic review that examined cognitive impairment in adults with LVH. Independent searches were performed in Ovid MEDLINE, Ovid psycInfo and PubMed with the terms left ventricular hypertrophy and cognition...
January 12, 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29327164/incremental-predictive-value-of-carotid-arterial-strain-in-patients-with-stroke
#19
Woo-In Yang, Ki-Woon Kang, Hye Young Lee, Chi-Young Shim, Geu-Ru Hong, Namsik Chung, Jong-Won Ha
Although increased carotid intima-media thickness (IMT) is a well-known risk factor for stroke, carotid IMT alone is not sufficient for risk stratification. The assessment of arterial properties using velocity vector imaging (VVI) represents a new method for quantifying structural changes. We sought to investigate the characteristics and the clinical value of carotid arterial mechanics using VVI in patients with stroke. Fifty male patients (55 ± 5 years) with stroke, 30 healthy age-matched volunteers (54 ± 8 years), and 30 healthy young male volunteers (29 ± 5 years) were evaluated...
January 11, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29326289/prevalence-of-hippocampal-enlarged-perivascular-spaces-in-a-sample-of-patients-with-hypertension-and-their-relation-with-vascular-risk-factors-and-cognitive-function
#20
Joan Jiménez-Balado, Iolanda Riba-Llena, Edurne Garde, Marta Valor, Belen Gutiérrez, Francesc Pujadas, Pilar Delgado
OBJECTIVES: The clinical importance of hippocampal enlarged perivascular spaces (H-EPVS) remains uncertain. We aimed to study their association with vascular risk factors, cognitive function and mild cognitive impairment (MCI). METHODS: Data were obtained from the ISSYS (Investigating Silent Strokes in hYpertensives, a magnetic resonance imaging Study) cohort, which is a prospective study of patients with hypertension aged 50-70 with no prior stroke or dementia...
January 11, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
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