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https://www.readbyqxmd.com/read/29150373/chromagar-msupercarba-and-rapidec%C3%A2-carba-np-test-for-detection-of-carbapenemase-producing-enterobacteriaceae
#1
Meritxell Garcia-Quintanilla, Laurent Poirel, Patrice Nordmann
A novel chromogenic medium CHROMagar mSuperCARBA was evaluated to detect carbapenem-resistant Gram-negatives. This medium is as sensitive and as specific as the SUPERCARBA medium for detecting KPC, MBL and OXA-48-type producers (100% and 100%, respectively) and is compatible with subsequent testing of carbapenemase activity using the RAPIDEC(®) CARBA NP.
October 19, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29148260/peri-implant-parameters-and-c-reactive-protein-levels-among-patients-with-different-obesity-levels
#2
Fahim Vohra, Fahad Alkhudhairy, Abdulaziz A Al-Kheraif, Zohaib Akram, Fawad Javed
BACKGROUND: It is hypothesized that peri-implant conditions are worse with increasing severity of obesity, because systemic low-grade inflammatory marker (C-reactive protein [CRP]) is higher in severe form of obese individuals. PURPOSE: The aim of the cross-sectional retrospective study was to compare clinical and radiographic peri-implant inflammatory parameters in patients with different levels of obesity and correlate these parameters with CRP levels. MATERIALS AND METHODS: Eighty-four patients who participated in this study were divided into 4 groups: class I obese (group 1), class II obese (group 2), class III obese (group 3), and nonobese individuals (group 4) were included...
November 16, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29140382/implant-mandibular-overdentures-retained-by-immediately-loaded-implants-a-1-year-randomized-trial-comparing-the-clinical-and-radiographic-outcomes-between-mini-dental-implants-and-standard-sized-implants
#3
Kostas Zygogiannis, Irene Ha Aartman, Azin Parsa, Ali Tahmaseb, Daniel Wismeijer
PURPOSE: The aim of this 1-year randomized trial was to evaluate and compare the clinical and radiographic performance of four immediately loaded mini dental implants (MDIs) and two immediately loaded standard-sized tissue-level (STL) implants, placed in the interforaminal region of the mandible and used to retain mandibular overdentures (IODs) in completely edentulous patients. MATERIALS AND METHODS: A total of 50 completely edentulous patients wearing conventional maxillary dentures and complaining about insufficient retention of their mandibular dentures were divided into two groups; 25 patients received four MDIs and 25 patients received two STL implants...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29140379/seven-year-follow-up-of-full-arch-prostheses-supported-by-four-implants-a-prospective-study
#4
Karen Vaz Ayub, Eduardo Antônio Ayub, Accácio Lins do Valle, Gerson Bonfante, Thiago Pegoraro, Luiz Fernando
PURPOSE: To evaluate biologic and prosthetic outcomes of implant-supported mandibular full-arch fixed prostheses treated with the All-on-4 treatment concept after 7 years. MATERIALS AND METHODS: Patients were selected to receive full-arch fixed immediate prostheses supported by four implants up to 72 hours after surgery. The following biologic aspects were evaluated: Plaque Index (PI) and Bleeding Index (BI), implant stability by resonance frequency, and marginal bone loss (MBL) measured with the aid of periapical radiographs...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29140373/clinical-considerations-of-adapted-drilling-protocol-by-bone-quality-perception
#5
Marco Toia, Michele Stocchero, Francesca Cecchinato, Enrico Corrà, Ryo Jimbo, Denis Cecchinato
PURPOSE: To evaluate insertion torque value (ITV) and marginal bone loss (MBL) of an implant system after a clinically perceived bone quality-adapted drilling. MATERIALS AND METHODS: This multicenter retrospective study included patients treated with implants, conventionally loaded, in completely healed sites. Operators customized the osteotomy preparation according to radiographic assessment and their perception of bone quality. Drilling sequence, bone quality, and ITV were recorded at the time of surgery...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29131134/mannose-binding-lectin-is-not-acting-as-a-biomarker-for-the-progression-of-pre-invasive-lesions-of-invasive-cervical-cancer
#6
Carlos Afonso Maestri, Renato Nisihara, Guilherme P Ramos, Hellen Weinschutz Mendes, Iara Messias-Reason, Newton Sérgio de Carvalho
OBJECTIVE: To evaluate serum concentrations of mannose binding lectin (MBL) in women presenting with different human papilloma virus (HPV)-associated cervical lesions. SUBJECTS AND METHODS: A total of 364 women, who underwent screening for cervical cancer or treatment at Erasto Gaertner Cancer Hospital (HEG), Curitiba, Southern region, Brazil, were enrolled in the study. Based on latest cervical colposcopy-guided biopsy results, the women were divided into four groups: cervical intraepithelial neoplasia (CIN) CIN-I (n=54); CIN-II (n=72); CIN-III (n=145) and invasive cancer (n=93)...
November 7, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29129586/mannose-binding-lectin-and-its-roles-in-immune-responses-in-grass-carp-ctenopharyngodon-idella-against-aeromonas-hydrophila
#7
Yunfei Dang, Xinzhan Meng, Shentong Wang, Lisen Li, Meng Zhang, Moyan Hu, Xiaoyan Xu, Yubang Shen, Liqun Lv, Rongquan Wang, Jiale Li
The complement system is a crucial component of the innate immune system that links innate and adaptive immunity via four pathways. Mannose-binding lectin (MBL), the initiating molecule of the lectin pathway, plays a significant role in the innate immune system in mammals and fish. Herein, we identified an MBL homolog (gcMBL) in grass carp (Ctenopharyngodon idella). The full-length 948 bp gcMBL cDNA includes a 741 bp open reading frame encoding a 246 amino acid protein with a signal peptide, collagen triple helix repeat domain, and a C-type lectin-like/link domain...
November 10, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29128031/development-of-a-menu-board-literacy-and-self-efficacy-scale-for-children
#8
Olajide Williams, Ellyn Leighton-Herrmann Quinn, Mildred Ramirez, Vanessa Sawyer, Joseph P Eimicke, Jeanne A Teresi
OBJECTIVE: An instrument to measure menu board literacy (MBL) was developed to capture children's understanding of menu board nutrition information, including abbreviations, serving sizes and calorie ranges, and self-efficacy for using this information. METHODS: A list of 55 potential items (47 MBL and 8 self-efficacy) was generated. Content validity was established by 29 registered dietitians. Cognitive interviews were conducted with 24 black and Hispanic fourth- and fifth-grade students to assess comprehension and readability...
November 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/29120581/serum-mannose-binding-lectin-in-egyptian-patients-with-chronic-hepatitis-c
#9
Laila M Yousef, Hesham M Hefny, Asmaa N Mohammad
Approximately 60 - 85% of HCV infections cannot eradicate the virus and progress to chronic hepatitis, this may be explained by failure in host immune responses or by the ability of HCV to defeat host defense mechanisms. Mannose-binding lectin (MBL) may play an immunomodulatory role. This work intended to evaluate the relationship of MBL concentration to chronic HCV infection. Two groups, a patient group (n=50) with chronic hepatitis C, and a control group, (n=35) apparently healthy non-infected subjects were studied...
January 2017: Egyptian Journal of Immunology
https://www.readbyqxmd.com/read/29119939/mannose-binding-lectin-protein-deficiency-among-patients-with-primary-immunodeficiency-disease-receiving-ivig-therapy
#10
Gholamreza Azizi, Fatemeh Kiaee, Naeimeh Tavakolinia, Hosein Rafiemanesh, Sara Mohammadikhajehdehi, Laleh Sharifi, Reza Yazdani, Hassan Abolhassani, Asghar Aghamohammadi
BACKGROUND: Primary immunodeficiencies (PIDs) are inherited disorders in which one or several components of the immune system are defective. Immunoglobulin replacement therapy is the mainstay of treatment for patients with impaired antibody production. However, recurrent infections would continue to occur in some patients due to the other high frequent concomitant defects such as mannose-binding lectin (MBL) deficiency. METHODS: A total of 51 PID patients participated in this cross-sectional study...
November 7, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29119559/preoperative-methylprednisolone-increases-plasma-pentraxin-3-early-after-total-knee-arthroplasty-a-randomized-double-blind-placebo-controlled-trial
#11
V Lindberg-Larsen, H Kehlet, K Pilely, J Bagger, M L Rovsing, P Garred
Preoperative glucocorticoid administration reduces the systemic inflammatory response. Pentraxin 3 (PTX3) is a novel inflammatory marker belonging to the humoral arm of innate immunity exerting a potentially protective host response. This study evaluated PTX3 and other complement marker changes after preoperative methylprednisolone (MP) early after total knee arthroplasty (TKA). Seventy patients were randomized (1 : 1) to preoperative intravenous (i.v.) MP 125 mg (group MP) or isotonic saline i.v. (group C)...
October 14, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/29112383/ozone-formation-induced-by-the-impact-of-reactive-bromine-and-iodine-species-on-photochemistry-in-a-polluted-marine-environment
#12
Moshe Shechner, Eran Tas
Reactive iodine and bromine species (RIS and RBS, respectively) are known for altering atmospheric chemistry, causing sharp tropospheric ozone (O3) depletion in polar regions and significant O3 reduction in the marine boundary layer (MBL). Here we use measurement-based modelling to show that, unexpectedly, both RIS and RBS can lead to enhanced O3 formation in a polluted marine environment under volatile organic compound (VOC)-limited conditions associated with high nitrogen oxide (NOX = [NO] + [NO2]) concentrations...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29110332/is-mbl-serum-concentration-a-reliable-predictor-for-recurrent-vulvovaginal-candidiasis
#13
Mona Ghazanfari, Mehraban Falahati, Azam Fattahi, Fatemeh Bazrafshan, Sanam Nami, Morteza Hosseinzadeh, Fariba Heydarikohan, Mohsen Ghelman, Majid Khoshmirsafa, Ali Farzanegan
BACKGROUND: Recurrent vulvovaginal candidiasis (RVVC) is acommon opportunistic, mucosal fungal infection, predominantly caused by the fungus Candida albicans.Mannose-binding lectin (MBL) is an acute-phase protein that plays a key role in the innate immunity defense against infectious disease. OBJECTIVES: The present study was conducted to evaluate the relationship between the MBL serum level and the relative expression of MBL mRNA in RVVC using real-time PCR for the first time...
November 6, 2017: Mycoses
https://www.readbyqxmd.com/read/29108580/development-of-flow-systems-incorporating-membraneless-vaporization-units-and-flow-through-contactless-conductivity-detector-for-determination-of-dissolved-ammonium-and-sulfide-in-canal-water
#14
Waleed Alahmad, Thanakorn Pluangklang, Thitirat Mantim, Victor Cerdà, Prapin Wilairat, Nuanlaor Ratanawimarnwong, Duangjai Nacapricha
Use of membraneless vaporization (MBL-VP) unit with two cone-shaped reservoirs is presented for on-line separation and detection of non-volatile species. A flow system comprising two sets of MBL-VP units with a single in-house capacitively coupled contactless conductivity detector (C4D) was developed for dual determination of ammonium and sulfide ions. Using the continuous-flow section, two zones (280μL) of a sample, either mixed with sodium hydroxide (for ammonium) or hydrochloric acid (for sulfide), are separately delivered into the donor reservoir of the MBL-VP units...
January 15, 2018: Talanta
https://www.readbyqxmd.com/read/29101284/genetic-mannose-binding-lectin-deficiency-is-associated-with-airway-microbiota-diversity-and-reduced-exacerbation-frequency-in-copd
#15
Alison J Dicker, Megan L Crichton, Andrew J Cassidy, Gill Brady, Adrian Hapca, Roger Tavendale, Gisli G Einarsson, Elizabeth Furrie, J Stuart Elborn, Stuart Schembri, Sara E Marshall, Colin N A Palmer, James D Chalmers
BACKGROUND: In cystic fibrosis and bronchiectasis, genetic mannose binding lectin (MBL) deficiency is associated with increased exacerbations and earlier mortality; associations in COPD are less clear. Preclinical data suggest MBL interferes with phagocytosis of Haemophilus influenzae, a key COPD pathogen. We investigated whether MBL deficiency impacted on clinical outcomes or microbiota composition in COPD. METHODS: Patients with COPD (n=1796) underwent MBL genotyping; linkage to health records identified exacerbations, lung function decline and mortality...
November 3, 2017: Thorax
https://www.readbyqxmd.com/read/29096652/biofilm-and-metallo-beta-lactamase-production-among-the-strains-of-pseudomonas-aeruginosa-and-acinetobacter-spp-at-a-tertiary-care-hospital-in-kathmandu-nepal
#16
Bandana Baniya, Narayan Dutt Pant, Sanjeev Neupane, Saroj Khatiwada, Uday Narayan Yadav, Nisha Bhandari, Rama Khadka, Sabita Bhatta, Raina Chaudhary
INTRODUCTION: Pseudomonas aeruginosa and Acinetobacter spp. are found to be associated with biofilm and metallo-β-lactamase production and are the common causes of serious infections mainly in hospitalized patients. So, the main aims of this study were to determine the rates of biofilm production and metallo beta-lactamase production (MBL) among the strains of Pseudomonas aeruginosa and Acinetobacter spp. isolated from hospitalized patients. METHODS: A total of 85 P...
November 2, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29094805/synthesis-of-naphthyridine-dimers-with-conformational-restriction-and-binding-to-dna-and-rna
#17
Kazuhiko Nakatani, Nozomi Natsuhara, Yuki Mori, Sanjukta Mukherjee, Bimolendu Das, Asako Murata
One of the important determinants in the efficiency of a molecular interaction is the necessity for conformational changes in host and/or guest molecules upon binding. In small-molecule interactions with nucleic acids, conformational changes on both molecules are often involved, especially in intercalating binding. Mismatch binding ligands (MBLs) we described here consist of two heterocycles that predominantly exist in one conformation, so it is of interest to determine if such molecules can bind to any DNA and RNA structures...
November 2, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29091730/probing-the-interaction-of-aspergillomarasmine-a-with-metallo-%C3%AE-lactamases-ndm-1-vim-2-and-imp-7
#18
Alexander Bergstrom, Andrew Katko, Zach Adkins, Jessica Hill, Zishuo Cheng, Mia Burnett, Hao Yang, Mahesh Aitha, M Rachel Mehaffey, Jennifer S Brodbelt, Kamaleddin H M E Tehrani, Nathaniel I Martin, Robert A Bonomo, Richard C Page, David L Tierney, Walter Fast, Gerard D Wright, Michael W Crowder
Metallo-β-lactamases (MBLs) are a growing threat to the continued efficacy of β-lactam antibiotics. Recently, aspergillomarasmine A (AMA) was identified as an MBL inhibitor, but the mode of inhibition was not fully characterized. Equilibrium dialysis and metal analysis studies revealed that 2 equiv of AMA effectively removes 1 equiv of Zn(II) from MBLs NDM-1, VIM-2, and IMP-7 when the MBL is at micromolar concentrations. Conversely, (1)H NMR studies revealed that 2 equiv of AMA remove 2 equiv of Co(II) from Co(II)-substituted NDM-1, VIM-2, and IMP-7 when the MBL/AMA are at millimolar concentrations...
November 9, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/29082655/immediately-restored-full-arch-fixed-prosthesis-on-implants-placed-in-both-healed-and-fresh-extraction-sockets-after-computer-planned-flapless-guided-surgery-a-3-year-follow-up-study
#19
Giampiero Ciabattoni, Alessandro Acocella, Roberto Sacco
BACKGROUND: The treatment of patients by the use of immediate implant placement in post-extractive site is a challenging procedure. PURPOSE: A 3-year clinical and radiological study of post-extractive implants placed using flapless guided surgery and immediately functioning. MATERIALS AND METHODS: Thirty-two patients (23 females and 9 males), aged between 44 and 73 years (a mean age of 59.5) were treated with immediate full arch restorations and flapless implant surgery in fresh extraction and healed sites...
October 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29054729/hib-antibody-responses-in-infants-following-diphtheria-tetanus-acellular-pertussis-and-conjugated-haemophilus-influenzae-type-b-hib-combination-vaccines-with-decreasing-amounts-of-tetanus-toxoid
#20
Henry H Bernstein, Elisabeth R Seyferth
BACKGROUND: While combination vaccines have contributed to improved vaccine uptake rates in children, studies have documented varied immunogenicity to specific vaccine components. We studied whether varying the amount of tetanus toxoid (TT) in a DTaP and Hib combination vaccine would result in immunogenicity comparable with separate, concurrent administration. METHODS: We evaluated the immunogenicity of Massachusetts Biologic Laboratories (MBL) diphtheria, tetanus, and acellular pertussis (mDTaP) vaccine combined with tetanus-conjugated MBL Haemophilus influenzae type b vaccine (mHib) in a single injection (DTaPH)...
October 17, 2017: Vaccine
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