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https://www.readbyqxmd.com/read/28944359/crestal-sinus-lift-using-an-implant-with-an-internal-l-shaped-channel-1-year-after-loading-results-from-a-prospective-cohort-study
#1
Marco Tallarico, David L Cochran, Erta Xhanari, Claudia Dellavia, Elena Canciani, Eitan Mijiritsky, Silvio Mario Meloni
PURPOSE: To evaluate the clinical and radiographic outcomes of a one-stage crestal sinus elevation procedure using a self-tapping endosseous implant system (iRaise, Maxillent, Herzliya, Israel) developed for sinus augmentation, 1 year after loading. MATERIALS AND METHODS: Patients needing restoration in the posterior maxilla with a residual alveolar crest of 3 to 8 mm in height and 5 mm in width distal to the canine as measured on CBCT scan were treated using the iRaise sinus lift system...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28940709/a-comparative-study-of-encode-protocol-versus-conventional-protocol-for-restoring-single-implants-one-year-prospective-randomized-controlled-clinical-trial
#2
Jaafar Abduo, Lakshmi Gade, Harjot Gill, Roy Judge, Ivan Darby
BACKGROUND: The Encode protocol (Biomet 3i, Palm Beach Gardens, Fla) has been proposed as a simplified implant restoration protocol. PURPOSE: To compare the 1-year clinical outcome of the Encode and conventional protocols for restoring single implants. MATERIALS AND METHODS: Forty-seven implants were inserted in 44 patients. After randomizing the implants, 24 implants were allocated to the Encode protocol and 23 implants were allocated to the conventional protocol...
September 21, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28939965/complement-immune-evasion-by-spirochetes
#3
Angela S Barbosa, Lourdes Isaac
The complement system plays an important role in the innate and acquired immune response against pathogens. A sophisticated network of activating and regulating proteins allows the distinction between intact and damaged host and non-host surfaces such as bacteria and other parasites. Non-host structures trigger the alternative pathway which may lead to their elimination by phagocytosis or cell lysis. In addition, complement proteins such as C1q, mannose binding lectin (MBL), and ficolins act as pathogen pattern-recognition molecules...
September 23, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28929963/-comparison-of-phenotypic-methods-and-polymerase-chain-reaction-for-the-detection-of-carbapenemase-production-in-clinical-klebsiella-pneumoniae-isolates
#4
Yamaç Tekintaş, Feriha Çilli, Bayrı Eraç, Melike Yaşar, Sabire Şöhret Aydemir, Mine Hoşgör Limoncu
Being a member of the Enterobacteriaceae family, Klebsiella pneumoniae is an opportunistic pathogen that inhabits normal human microbiota and causes predominantly hospital-acquired infections. The emergence of K.pneumoniae isolates which are resistant particularly to the carbapenem group of antibiotics has led to an increase in hospitalization period, mortality and morbidity. Although different rates of resistance are observed between countries, regions and even healthcare facilities, there has been a rapid increase in the prevalence of carbapenem-resistant strains in the last 10 years...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28927454/extended-spectrum-beta-lactamase-and-metallo-beta-lactamase-production-among-escherichia-coli-and-klebsiella-pneumoniae-isolated-from-different-clinical-samples-in-a-tertiary-care-hospital-in-kathmandu-nepal
#5
Krishus Nepal, Narayan Dutt Pant, Bibhusan Neupane, Ankit Belbase, Rikesh Baidhya, Ram Krishna Shrestha, Binod Lekhak, Dwij Raj Bhatta, Bharat Jha
BACKGROUND: Extended spectrum beta-lactamase (ESBL) and metallo beta-lactamase (MBL) production in Klebsiella pneumoniae and Escherichia coli are the commonest modes of drug resistance among these commonly isolated bacteria from clinical specimens. So the main purpose of our study was to determine the burden of ESBL and MBL production in E. coli and K. pneumoniae isolated from clinical samples. Further, the antimicrobial susceptibility patterns of E. coli and K. pneumoniae were also determined...
September 19, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28923270/definitive-abutments-placed-at-implant-insertion-and-never-removed-is-it-an-effective-approach-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#6
REVIEW
Marco Tallarico, Martina Caneva, Silvio Mario Meloni, Erta Xhanari, Ugo Covani, Luigi Canullo
PURPOSE: To assess whether repeated abutment disconnections and reconnections have any impact on peri-implant bone resorption and soft tissue healing. MATERIALS AND METHODS: Electronic and manual searches were conducted for English-language articles published up to March 2017 that identified a relation between repeated disconnections of implant abutments (PA group) and prosthetic or implant failures, complications, marginal bone loss (MBL), soft tissue healing, and esthetic evaluation (pink esthetic score [PES]) after at least 1 year of function compared with implants receiving a final abutment at the time of implant placement (DA group)...
August 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28918528/signaling-of-the-complement-cleavage-product-anaphylatoxin-c5a-through-c5ar-cd88-contributes-to-pharmacological-hematopoietic-stem-cell-mobilization
#7
Kamila Bujko, Sylwia Rzeszotek, Kai Hoehlig, Jun Yan, Axel Vater, Mariusz Z Ratajczak
Several mechanisms have been postulated for orchestrating the mobilization of hematopoietic stem/progenitor cells (HSPCs), and we previously proposed that activation of the complement cascade plays a crucial role in the initiation and execution of the egress of HSPCs from bone marrow (BM) into peripheral blood (PB). In support of this notion, we demonstrated that mice deficient in the mannan-binding lectin (MBL) pathway, which activates the proximal part of the complement cascade, as well as mice deficient in the fifth component of the complement cascade (C5), which is part of the distal part of the complement cascade, are poor mobilizers...
September 16, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28906508/a-prospective-case-control-clinical-study-of-titanium-zirconium-alloy-implants-with-a-hydrophilic-surface-in-patients-with-type-2-diabetes-mellitus
#8
José Cabrera-Domínguez, Lizett Castellanos-Cosano, Daniel Torres-Lagares, Guillermo Machuca-Portillo
PURPOSE: To evaluate prospectively the behavior of narrow-diameter (3.3-mm) titanium-zirconium alloy implants with a hydrophilic surface (Straumann Roxolid SLActive) in patients with type 2 diabetes mellitus in single-unit restorations, compared with a healthy control group (assessed using the glycosylated hemoglobin HbA1c test). MATERIALS AND METHODS: The patients evaluated in this study required single-unit implant treatment; 15 patients had type 2 diabetes mellitus, and 14 patients were healthy (control group [CG])...
September 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28903342/patients-with-chronic-lymphocytic-leukemia-and-complex-karyotype-show-an-adverse-outcome-even-in-absence-of-tp53-atm-fish-deletions
#9
Anna Puiggros, Rosa Collado, Maria José Calasanz, Margarita Ortega, Neus Ruiz-Xivillé, Alfredo Rivas-Delgado, Elisa Luño, Teresa González, Blanca Navarro, MaDolores García-Malo, Alberto Valiente, José Ángel Hernández, María Teresa Ardanaz, María Ángeles Piñan, María Laura Blanco, María Hernández-Sánchez, Ana Batlle-López, Rocío Salgado, Marta Salido, Ana Ferrer, Pau Abrisqueta, Eva Gimeno, Eugènia Abella, Christelle Ferrá, María José Terol, Francisco Ortuño, Dolors Costa, Carol Moreno, Félix Carbonell, Francesc Bosch, Julio Delgado, Blanca Espinet
Genomic complexity identified by chromosome banding analysis (CBA) predicts a worse clinical outcome in CLL patients treated either with standard or new treatments. Herein, we analyzed the clinical impact of complex karyotypes (CK) with or without high-risk FISH deletions (ATM and/or TP53, HR-FISH) in a cohort of 1045 untreated MBL/CLL patients. In all, 99/1045 (9.5%) patients displayed a CK. Despite ATM and TP53 deletions were more common in CK (25% vs 7%; P < 0.001; 40% vs 5%; P < 0.001, respectively), only 44% (40/90) patients with TP53 deletions showed a CK...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28898115/mannose-binding-lectin-deficiency-and-miscarriages-in-rheumatoid-arthritis
#10
Juliana Z Cieslinski, Isabela Goeldner, Thelma L Skare, Renato Nisihara, Fabiana A De Andrade, Thirumalaisamy P Velavan, Iara Messias-Reason, Shirley R R Utiyama
OBJECTIVE: To investigate the association between mannose-binding lectin (MBL) serum level and MBL2 polymorphisms, and the frequency of spontaneous miscarriages in rheumatoid arthritis (RA) patients. METHODS: One hundred seventy seven women (mean age 50 years) with RA from Southern Brazil were studied and 4.5% had a history of abortion (8/177). The MBL levels were determined by ELISA. MBL2 polymorphisms in the promoter (-550H/L, -221X/Y), 5' untranslated region (4 P/Q) and exon 1 (p...
September 12, 2017: Autoimmunity
https://www.readbyqxmd.com/read/28888401/detection-of-carbapenemases-and-other-mechanisms-of-enzymatic-resistance-to-%C3%AE-lactams-in-enterobacteriaceae-with-diminished-susceptibility-to-carbapenems-in-a-tertiary-care-hospital
#11
Marta María Gómara-Lomero, Ana Isabel López-Calleja, Berta María Pilar Vela Iglesia, Isabel Ferrer Cerón, Antonio Rezusta López, María José Revillo Pinilla
INTRODUCTION: Our objective was to characterize the enzymatic β-lactam resistance in clinical Enterobacteriaceae isolates with diminished susceptibility to carbapenems from 2013 to 2014 at Hospital Universitario Miguel Servet. MATERIAL/METHODS: A total of 63 clinical isolates were analyzed for the presence of carbapenemases (KPC, OXA-48 and MBL), ESBLs and AmpC enzymes by combined disk methods and PCR detection of carbapenemase-encoding and beta-lactamase-encoding genes...
September 6, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28879439/mannose-binding-lectin-mbl-deficiency-and-tuberculosis-infection-in-patients-with-ankylosing-spondylitis
#12
Renato Nisihara, Thelma Skare, Vinícius Maestri, Juliana S Alegretti, Ana Paula B Campos, Iara Messias-Reason
Ankylosing spondylitis (AS) patients may have higher prevalence of mannose-binding lectin (MBL) deficiency than normal individuals. MBL deficiency may influence susceptibility to infections. The aim of the study was to verify if MBL deficiency in patients with AS predisposes to infections. We studied 60 patients with AS diagnosed according to the Assessment of SpondyloArthritis international Society (ASAS) criteria. These patients had their MBL serum levels determinated. Twenty-five individuals were identified as MBL deficient (serum values 100 ng/mL)...
September 6, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28876169/ndm-1-hazard-in-the-balkan-states-evidence-of-the-first-outbreak-of-ndm-1-producing-klebsiella-pneumoniae-in-bulgaria
#13
Encho Savov, Lida Politi, Nicholas Spanakis, Angelina Trifonova, Elena Kioseva, Athanasios Tsakris
New Delhi MBL (NDM) carbapenemase-producing Klebsiella pneumoniae has become one of the most concerning multidrug-resistant pathogens. The Balkan counties are considered a reservoir for the spread of such strains based on several reports documenting NDM infections after hospitalization in this region. Nevertheless, NDM-producing K. pneumoniae have been only occasionally documented from Balkans. The current study documents the first polyclonal outbreak caused by NDM-1-producing K. pneumoniae in Bulgaria. From July 2015 to April 2016, all 25 single-patient carbapenem-nonsusceptible K...
September 6, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28865818/single-vs-2-implants-on-peri-implant-marginal-bone-level-and-implant-failures-in-mandibular-implant-overdentures-a-systematic-review-with-meta-analysis
#14
REVIEW
Dina Mohamed Ahmed Elawady, Amal Fathy Kaddah, Mohamed Talaat Khalifa
BACKGROUND: As a consensus, the 2-implant supported overdentures (ODs) are considered as the first choice of treatment for the edentulous mandible. In the same context, there is increased evidence supporting the use of single-implant OD. The aim of any design is to preserve the remaining structures and allow the longevity of the treatment. OBJECTIVES: To evaluate the impact of single implant vs 2 implants on the peri-implant marginal bone loss (MBL) and number of implant failures in mandibular implant overdentures...
September 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28864337/complement-genomics-and-antibody-mediated-rejection-in-heart-recipients
#15
EDITORIAL
Javier Carbone
In this issue of the Journal of Heart and Lung Transplantation, Marrón-Liñares et al report the results of an interesting study in which they evaluated 51 genes associated with the complement pathway in a small number of heart recipients to explore their relationship with antibody-mediated rejection (AMR). Next-generation sequencing was used in 46 heart transplant recipients (23 with AMR and 23 without AMR). The authors identified a significant association of 2 single-nucleotide polymorphisms with the absence or presence of AMR, respectively, p...
August 19, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28862720/effect-of-the-different-implant-protocols-on-peri-implant-bone-a-6-month-prospective-study-in-beagle-dogs
#16
Dandan Song, Hui Zheng, Yan Huang, Xucheng Ma, Guowu Ma, Xin Liang
OBJECTIVE: To compare the effects of different implant placement and loading protocols on the marginal bone loss (MBL) in beagles by intraoral radiography. METHODS AND MATERIALS: 61 dental implants were inserted on 9 beagle dogs at bilateral lower posteriors according to 8 different protocols: immediate implant placement and immediate loading for 3 months (IIP + IL3) or 6 months (IIP + IL6) and unloading (IIP + UL), immediate implant placement and delayed loading for 3 months (IIP + DL3) or 6 months (IIP + DL6), delayed implant placement and immediate loading for 3 months (DIP + IL3) or delayed loading for 3 months (DIP + DL3) and unloading (DIP + UL)...
August 11, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28859500/emergence-of-ndm-1-among-carbapenem-resistant-klebsiella-pneumoniae-in-iraqi-hospitals
#17
Nadheema Hammood Hussein
Carbapenems are the last drugs of choice apart from colistin against serious infections caused by Gram-negative bacteria. However, there are increasing number of reports indicating prevailing emergence of metallo-β-lactamase (MBL)-producing clinical isolates worldwide and among them New Delhi MBL (NDM) is the most prevalent one. This study reports NDM-1 for the first time among Klebsiella pneumoniae from hospitalized patients in Baghdad, Iraq. Fifty-five clinical isolates of K. pneumoniae resistant to carbapenem were investigated from burned wounds, sputum, and blood samples...
September 1, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28858647/hair-segmentation-using-adaptive-threshold-from-edge-and-branch-length-measures
#18
Ian Lee, Xian Du, Brian Anthony
BACKGROUND: Non-invasive imaging techniques allow the monitoring of skin structure and diagnosis of skin diseases in clinical applications. However, hair in skin images hampers the imaging and classification of the skin structure of interest. Although many hair segmentation methods have been proposed for digital hair removal, a major challenge in hair segmentation remains in detecting hairs that are thin, overlapping, of similar contrast or color to underlying skin, or overlaid on highly-textured skin structure...
August 24, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28853215/survival-rate-of-titanium-zirconium-narrow-diameter-dental-implants-versus-commercially-pure-titanium-narrow-diameter-dental-implants-a-systematic-review
#19
Carolina Mayumi Iegami, Priscila Nakasone Uehara, Newton Sesma, Cláudio Mendes Pannuti, Pedro Tortamano Neto, Márcio Katsuyoshi Mukai
BACKGROUND: Despite the existence of several studies validating the use of narrow diameter implants, most of them are based on pure Ti alloys. There is few clinical evidence of the success of TiZr narrow diameter implants (TiZr NDIs) regarding survival rate (SR) and marginal bone loss (MLB). PURPOSE: The aim of this review was to systematically assess SR, as well as MBL of TiZr NDIs compared to commercially pure titanium narrow diameter implants (cpTi NDIs). MATERIAL AND METHODS: The search was conducted in Medline/PubMed, Cochrane, Scopus, and Embase databases (year 2000 to November 2016)...
August 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28853203/transcrestal-sinus-floor-augmentation-with-immediate-implant-placement-applied-in-three-types-of-fresh-extraction-sockets-a-clinical-prospective-study-with-1-year-follow-up
#20
Yaqian Chen, Shanshan Yuan, Nan Zhou, Yi Man
BACKGROUND: Immediate implant insertion and transcrestal sinus augmentation both can provide a lot of advantages for patients and clinicians. OBJECTIVE: This prospective study aims to verify the use of a modified technique for immediate implant insertion simultaneously with sinus augmentation in different types of sockets. MATERIALS AND METHODS: Thirty-seven patients were recruited for the clinical study and were divided into 3 groups according to the relationship of their maxillary molar roots and sinus floor: group 1 with none of the teeth roots contacts sinus floor; group 2 as at least 1 teeth root contacting sinus floor, but no root is observed penetrating into sinus cavity; group 3 with at least 1 teeth root penetrating into sinus cavity...
August 29, 2017: Clinical Implant Dentistry and related Research
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