keyword
https://read.qxmd.com/read/38536889/multilocus-sequence-typing-and-antibiotic-resistance-of-aeromonas-isolated-from-freshwater-fish-in-hebei-province
#1
JOURNAL ARTICLE
Zixiao Yu, Yunseok Oh, Songmi Kim, Kyudong Han, Kornsorn Srikulnath, Qingyang Li, Ji-Seok Jang, Ho-Seong Lee
Aeromonas spp. are the opportunistic pathogens that infect both aquatic and terrestrial homeotherms. They were commonly present in aquatic environments, including effluent, tap water, marine, river, and lake, where they are often isolated from aquatic animals, including fish, molluscs, and crustaceans. The Aeromonas infections can cause sepsis, ulcer, and other symptoms, resulting in the death of massive aquatic animals. Therefore, the prevention and control of Aeromonas is of great significance for the healthy development of aquaculture...
2024: PloS One
https://read.qxmd.com/read/38536098/-escherichia-coli-isolated-from-bovine-sources-encoding-the-fosfomycin-resistance-gene-fosa7-5
#2
JOURNAL ARTICLE
Bradd J Haley, Seon Woo Kim, Jo Ann Van Kessel
Dairy animals are reservoirs of antimicrobial-resistant Escherichia coli that are frequently resistant to tetracycline, aminoglycoside, β-lactam, sulfonamide, and macrolide-lincosamide-streptogramin B antibiotics. However, resistance to other classes of antimicrobials is less frequently observed, and resistance to fosfomycin is rarely observed in E. coli . In this study, we describe the genomic characteristics of E. coli encoding fosA7.5 that have been recovered from bovine sources in the United States...
March 27, 2024: Foodborne Pathogens and Disease
https://read.qxmd.com/read/38535888/characteristics-of-pathogenic-escherichia-coli-associated-with-diarrhea-in-children-under-five-years-in-northwestern-ethiopia
#3
JOURNAL ARTICLE
Berihun Mossie Mulu, Mequanint Addisu Belete, Tiliksew Bialfew Demlie, Habtamu Tassew, Tesfaye Sisay Tessema
Diarrheagenic Escherichia coli (DEC) are the leading cause of infectious diarrhea and pose a significant global, regional, and national burden of disease. This study aimed to investigate the prevalence of six DEC pathotypes in children with diarrhea and determine their antibiotic resistance patterns. Samples from 107 diarrheagenic children were collected and processed for Escherichia coli ( E. coli ). Single-plex PCR was used to detect target virulence genes as well as characterize and categorize DEC pathotypes...
March 21, 2024: Tropical Medicine and Infectious Disease
https://read.qxmd.com/read/38535887/multiple-drug-resistant-shiga-toxin-producing-e-coli-in-raw-milk-of-dairy-bovine
#4
JOURNAL ARTICLE
Safir Ullah, Saeed Ul Hassan Khan, Muhammad Jamil Khan, Baharullah Khattak, Fozia Fozia, Ijaz Ahmad, Mohammad Ahmad Wadaan, Muhammad Farooq Khan, Almohannad Baabbad, Sagar M Goyal
INTRODUCTION: Raw milk may contain pathogenic microorganisms harmful to humans, e.g., multidrug-resistant Escherichia coli non-O157:H7, which can cause severe colitis, hemolytic uremia, and meningitis in children. No studies are available on the prevalence of Shiga toxin-producing E. coli (STEC O157:H7) in sick or healthy dairy animals in the Khyber Pakhtunkhwa Province of Pakistan. AIM: This study aimed to isolate, characterize, and detect antibiotic resistance in STEC non-O157:H7 from unpasteurized milk of dairy bovines in this province...
March 19, 2024: Tropical Medicine and Infectious Disease
https://read.qxmd.com/read/38534711/sub-mic-antibiotics-modulate-productions-of-outer-membrane-vesicles-in-tigecycline-resistant-escherichia-coli
#5
JOURNAL ARTICLE
Qianru Li, Jun Li, Tao He, Xing Ji, Ruicheng Wei, Meiling Yu, Ran Wang
Antimicrobial resistance (AMR) has been recognized as one of the most important crises affecting global human health in the 21st century. Tigecycline is one of the last resort antibiotics for treating severe infections caused by multi-drug resistant Enterobacteriaceae . However, the mobile resistance gene tet (X4), which could mediate high-level tigecycline resistance, was discovered in 2019. The outer membrane vesicle (OMV) has been recognized as a new route for horizontal gene transfer; antimicrobial resistant bacteria also have the ability to secret OMVs, while little is known about the impact of antibiotics on the secretion and characteristics of OMVs from tigecycline resistant bacteria till now...
March 19, 2024: Antibiotics
https://read.qxmd.com/read/38534710/phenotypic-and-genotypic-characterization-of-pan-drug-resistant-klebsiella-pneumoniae-isolated-in-qatar
#6
JOURNAL ARTICLE
Mazen A Sid Ahmed, Jemal M Hamid, Ahmed M M Hassan, Sulieman Abu Jarir, Emad Bashir Ibrahim, Hamad Abdel Hadi
In secondary healthcare, carbapenem-resistant Enterobacterales (CREs), such as those observed in Klebsiella pneumoniae , are a global public health priority with significant clinical outcomes. In this study, we described the clinical, phenotypic, and genotypic characteristics of three pan-drug-resistant (PDR) isolates that demonstrated extended resistance to conventional and novel antimicrobials. All patients had risk factors for the acquisition of multidrug-resistant organisms, while microbiological susceptibility testing showed resistance to all conventional antimicrobials...
March 19, 2024: Antibiotics
https://read.qxmd.com/read/38534706/antimicrobial-action-mechanisms-of-natural-compounds-isolated-from-endophytic-microorganisms
#7
REVIEW
Farkhod Eshboev, Nilufar Mamadalieva, Pavel A Nazarov, Hidayat Hussain, Vladimir Katanaev, Dilfuza Egamberdieva, Shakhnoz Azimova
Infectious diseases are a significant challenge to global healthcare, especially in the face of increasing antibiotic resistance. This urgent issue requires the continuous exploration and development of new antimicrobial drugs. In this regard, the secondary metabolites derived from endophytic microorganisms stand out as promising sources for finding antimicrobials. Endophytic microorganisms, residing within the internal tissues of plants, have demonstrated the capacity to produce diverse bioactive compounds with substantial pharmacological potential...
March 18, 2024: Antibiotics
https://read.qxmd.com/read/38534700/the-clinical-efficacy-of-adding-ceftazidime-avibactam-to-standard-therapy-in-treating-infections-caused-by-carbapenem-resistant-klebsiella-pneumonia-with-blaoxa-48-like-genes
#8
JOURNAL ARTICLE
Al Maamon R Abu Jaber, Bilgen Basgut, Ali Abdullah Hawan, Ali Amer Al Shehri, Sultan Ahmad AlKahtani, Nehad J Ahmed, Abdikarim Abdi
Ceftazidime/avibactam (CAZ-AVI) is FDA-approved for managing infections caused by resistant gram-negative bacilli, particularly infections via carbapenem-resistant Enterobacterales pathogens. The clinical data are still limited, particularly those in Saudi Arabia. The present study is a retrospective cohort study that was carried out at the Armed Forces Hospital in the southern region of Saudi Arabia to compare the clinical and microbiological outcomes for CAZ-AVI-treated patients as monotherapy and as an add-on to standard therapy for carbapenem-resistant Klebsiella pneumonia (CRKP) OXA-48 infections to those treated with standard drugs...
March 16, 2024: Antibiotics
https://read.qxmd.com/read/38534699/generation-and-characterization-of-stable-small-colony-variants-of-usa300-staphylococcus-aureus-in-raw-264-7-murine-macrophages
#9
JOURNAL ARTICLE
Dalida Bivona, Carmelo Bonomo, Lorenzo Colombini, Paolo G Bonacci, Grete F Privitera, Giuseppe Caruso, Filippo Caraci, Francesco Santoro, Nicolò Musso, Dafne Bongiorno, Francesco Iannelli, Stefania Stefani
Intracellular survival and immune evasion are typical features of staphylococcal infections. USA300 is a major clone of methicillin-resistant S. aureus (MRSA), a community- and hospital-acquired pathogen capable of disseminating throughout the body and evading the immune system. Carnosine is an endogenous dipeptide characterized by antioxidant and anti-inflammatory properties acting on the peripheral (macrophages) and tissue-resident (microglia) immune system. In this work, RAW 264.7 murine macrophages were infected with the USA300 ATCC BAA-1556 S...
March 16, 2024: Antibiotics
https://read.qxmd.com/read/38534697/post-covid-19-pandemic-rebound-of-macrolide-resistant-mycoplasma-pneumoniae-infection-a-descriptive-study
#10
JOURNAL ARTICLE
Fan-Fan Xing, Kelvin Hei-Yeung Chiu, Chao-Wen Deng, Hai-Yan Ye, Lin-Lin Sun, Yong-Xian Su, Hui-Jun Cai, Simon Kam-Fai Lo, Lei Rong, Jian-Liang Chen, Vincent Chi-Chung Cheng, David Christopher Lung, Siddharth Sridhar, Jasper Fuk-Woo Chan, Ivan Fan-Ngai Hung, Kwok-Yung Yuen
The rebound characteristics of respiratory infections after lifting pandemic control measures were uncertain. From January to November 2023, patients presenting at a teaching hospital were tested for common respiratory viruses and Mycoplasma pneumoniae using a combination of antigen, nucleic acid amplification, and targeted next-generation sequencing (tNGS) tests. The number and rate of positive tests per month, clinical and microbiological characteristics were analyzed. A rapid rebound of SARS-CoV-2 was followed by a slower rebound of M...
March 15, 2024: Antibiotics
https://read.qxmd.com/read/38534694/detection-of-extended-spectrum-beta-lactamase-esbl-producing-enterobacteriaceae-from-diseased-broiler-chickens-in-lusaka-district-zambia
#11
JOURNAL ARTICLE
Chikwanda Chileshe, Misheck Shawa, Nelson Phiri, Joseph Ndebe, Cynthia Sipho Khumalo, Chie Nakajima, Masahiro Kajihara, Hideaki Higashi, Hirofumi Sawa, Yasuhiko Suzuki, Walter Muleya, Bernard Mudenda Hang'ombe
Poultry products in Zambia form an integral part of the human diet in many households, as they are cheap and easy to produce. The burden of poultry diseases has, however, remained a major challenge. Growing consumer demand for poultry products in Zambia has resulted in non-prudent antimicrobial use on farms, intending to prevent and treat poultry diseases for growth optimisation and maximising profits. This cross-sectional study aimed to identify the different types of bacteria causing diseases in chickens in Lusaka and to detect the extended-spectrum lactamase (ESBL)-encoding genes...
March 15, 2024: Antibiotics
https://read.qxmd.com/read/38534686/antimicrobial-properties-of-colostrum-and-milk
#12
REVIEW
Furkan Eker, Emir Akdaşçi, Hatice Duman, Yalçın Mert Yalçıntaş, Ahmet Alperen Canbolat, Arda Erkan Kalkan, Sercan Karav, Dunja Šamec
The growing number of antibiotic resistance genes is putting a strain on the ecosystem and harming human health. In addition, consumers have developed a cautious attitude towards chemical preservatives. Colostrum and milk are excellent sources of antibacterial components that help to strengthen the immunity of the offspring and accelerate the maturation of the immune system. It is possible to study these important defenses of milk and colostrum, such as lactoferrin, lysozyme, immunoglobulins, oligosaccharides, etc...
March 11, 2024: Antibiotics
https://read.qxmd.com/read/38534682/in-vitro-microevolution-and-co-selection-assessment-of-amoxicillin-and-cefotaxime-impact-on-escherichia-coli-resistance-development
#13
JOURNAL ARTICLE
Ádám Kerek, Bence Török, Levente Laczkó, Zoltán Somogyi, Gábor Kardos, Krisztián Bányai, Eszter Kaszab, Krisztina Bali, Ákos Jerzsele
The global spread of antimicrobial resistance has become a prominent issue in both veterinary and public health in the 21st century. The extensive use of amoxicillin, a beta-lactam antibiotic, and consequent resistance development are particularly alarming in food-producing animals, with a focus on the swine and poultry sectors. Another beta-lactam, cefotaxime, is widely utilized in human medicine, where the escalating resistance to third- and fourth-generation cephalosporins is a major concern. The aim of this study was to simulate the development of phenotypic and genotypic resistance to beta-lactam antibiotics, focusing on amoxicillin and cefotaxime...
March 7, 2024: Antibiotics
https://read.qxmd.com/read/38534680/whole-genome-sequencing-reveals-antimicrobial-resistance-and-virulence-genes-of-both-pathogenic-and-non-pathogenic-b-cereus-group-isolates-from-foodstuffs-in-thailand
#14
JOURNAL ARTICLE
Phornphan Sornchuer, Kritsakorn Saninjuk, Sumet Amonyingcharoen, Jittiporn Ruangtong, Nattaya Thongsepee, Pongsakorn Martviset, Pathanin Chantree, Kant Sangpairoj
Members of the Bacillus cereus group are spore-forming Gram-positive bacilli that are commonly associated with diarrheal or emetic food poisoning. They are widespread in nature and frequently present in both raw and processed food products. Here, we genetically characterized 24 B. cereus group isolates from foodstuffs. Whole-genome sequencing (WGS) revealed that most of the isolates were closely related to B. cereus sensu stricto (12 isolates), followed by B. pacificus (5 isolates), B. paranthracis (5 isolates), B...
March 7, 2024: Antibiotics
https://read.qxmd.com/read/38534677/assessing-the-microbial-quality-of-shrimp-xiphonaeus-kroyeri-and-mussels-perna-perna-illegally-sold-in-the-vit%C3%A3-ria-region-brazil-and-investigating-the-antimicrobial-resistance-of-escherichia-coli-isolates
#15
JOURNAL ARTICLE
Daniella Tosta Link, Gustavo Guimarães Fernandes Viana, Lívia Pasolini Siqueira, Carolina Magri Ferraz, Romário Alves Rodrigues, Luis Antonio Mathias, Marita Vedovelli Cardozo, Gabriel Augusto Marques Rossi
The consumption of seafood is crucial for food security, but poor hygiene along the food production chain can result in low microbiological quality, posing significant risks for public health and seafood quality. Thus, this study aimed to assess the microbiological quality and antimicrobial sensitivity of E. coli from 69 samples of illegally marketed shrimp and mussels in the Vitória Region, Brazil. These foods exhibited poor microbiological quality due to high counts of mesophilic, psychrotrophic, and enterobacteria microorganisms...
March 6, 2024: Antibiotics
https://read.qxmd.com/read/38534669/-scolopax-rusticola-carrying-enterobacterales-harboring-antibiotic-resistance-genes
#16
JOURNAL ARTICLE
Valeria Gargano, Delia Gambino, Adriana Maria Oddo, Mariangela Pizzo, Arianna Sucato, Gaetano Cammilleri, Francesco La Russa, Maria Liliana Di Pasquale, Maria Giovanna Parisi, Giovanni Cassata, Giuseppe Giangrosso
The Eurasian woodcock ( Scolopax rusticola ) belongs to those bird species that make systematic migratory flights in spring and autumn in search of favorable breeding and wintering areas. These specimens arrive in the Mediterranean Area from northeastern European countries during the autumn season. The purpose of this study was to assess whether woodcocks can carry antibiotic resistance genes (ARGs) along their migratory routes. Although the role of migratory birds in the spread of some zoonotic diseases (of viral and bacterial etiology) has been elucidated, the role of these animals in the spread of antibiotic resistance has not yet been clarified...
March 2, 2024: Antibiotics
https://read.qxmd.com/read/38534662/first-report-of-colistin-resistant-escherichia-coli-carrying-mcr-1-inci2-delta-and-incx4-plasmids-from-camels-camelus-dromedarius-in-the-gulf-region
#17
JOURNAL ARTICLE
Akela Ghazawi, Nikolaos Strepis, Febin Anes, Dana Yaaqeib, Amal Ahmed, Aysha AlHosani, Mirah AlShehhi, Ashrat Manzoor, Ihab Habib, Nisar A Wani, John P Hays, Mushtaq Khan
Addressing the emergence of antimicrobial resistance (AMR) poses a significant challenge in veterinary and public health. In this study, we focused on determining the presence, phenotypic background, and genetic epidemiology of plasmid-mediated colistin resistance ( mcr ) in Escherichia coli bacteria isolated from camels farmed in the United Arab Emirates (UAE). Fecal samples were collected from 50 camels at a Dubai-based farm in the UAE and colistin-resistant Gram-negative bacilli were isolated using selective culture...
February 28, 2024: Antibiotics
https://read.qxmd.com/read/38534659/predictive-modeling-of-phenotypic-antimicrobial-susceptibility-of-selected-beta-lactam-antimicrobials-from-beta-lactamase-resistance-genes
#18
JOURNAL ARTICLE
Md Kaisar Rahman, Ryan B Williams, Samuel Ajulo, Gizem Levent, Guy H Loneragan, Babafela Awosile
The outcome of bacterial infection management relies on prompt diagnosis and effective treatment, but conventional antimicrobial susceptibility testing can be slow and labor-intensive. Therefore, this study aims to predict phenotypic antimicrobial susceptibility of selected beta-lactam antimicrobials in the bacteria of the family Enterobacteriaceae from different beta-lactamase resistance genotypes. Using human datasets extracted from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program conducted by Pfizer and retail meat datasets from the National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS), we used a robust or weighted least square multivariable linear regression modeling framework to explore the relationship between antimicrobial susceptibility data of beta-lactam antimicrobials and different types of beta-lactamase resistance genes...
February 28, 2024: Antibiotics
https://read.qxmd.com/read/38534653/community-emergence-of-cefixime-resistant-escherichia-coli-belonging-to-st12-with-chromosomal-ampc-hyperproduction
#19
JOURNAL ARTICLE
Gloria Zaragoza, María Pérez-Vázquez, Laura Villar-Gómara, Andrea González-Prieto, Jesús Oteo-Iglesias, Juan-Ignacio Alós
Escherichia coli isolates that are resistant to cefixime and amoxicillin/clavulanic acid, but apparently susceptible to cefuroxime, with no ESBL identified, were initially detected in Madrid from urine samples in 2019. Throughout 2020 and 2021, all cases of community UTI by E. coli from six health areas in Madrid were studied. A representative sample of 23 cases was selected for further studies. The broth microdilution method and the agar diffusion method were performed to determine the antibiotic susceptibility...
February 27, 2024: Antibiotics
https://read.qxmd.com/read/38534648/risk-factors-associated-with-mortality-in-acinetobacter-baumannii-infections-results-of-a-prospective-cohort-study-in-a-tertiary-public-hospital-in-guayaquil-ecuador
#20
JOURNAL ARTICLE
Luz Abarca-Coloma, Miguel Puga-Tejada, Tamara Nuñez-Quezada, Otilia Gómez-Cruz, Carlos Mawyin-Muñoz, Shivan Barungi, Macarena Perán
Antibiotic overuse and the resulting antimicrobial resistance pose significant global public health challenges, providing an avenue for opportunistic pathogens like Acinetobacter baumannii to thrive. This study will report the trends of Acinetobacter baumannii antimicrobial resistance patterns at the Hospital Teodoro Maldonado Carbo, Ecuador. An observational, analytical, longitudinal, and prospective study was conducted involving patients diagnosed with hospital-acquired infections. Antimicrobial susceptibility testing was performed, followed by molecular analysis of carbapenemase genes in Acinetobacter baumannii isolates...
February 23, 2024: Antibiotics
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