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https://www.readbyqxmd.com/read/29775168/dysphagia-in-supratentorial-recent-small-subcortical-infarcts-results-from-bilateral-pyramidal-tract-damage
#1
Simon Fandler, Thomas Gattringer, Daniela Pinter, Lukas Pirpamer, Florian Borsodi, Sebastian Eppinger, Kurt Niederkorn, Christian Enzinger, Franz Fazekas
Background Dysphagia occurs in up to 20% of patients with a recent small subcortical infarct, even when excluding brainstem infarcts. Aim To examine the impact of lesion topography and concomitant cerebrovascular lesions on the occurrence of dysphagia in patients with a single supratentorial recent small subcortical infarct. Methods We retrospectively identified all inpatients with magnetic resonance imaging-confirmed supratentorial recent small subcortical infarcts over a five-year period. Dysphagia was determined by speech-language therapists...
January 1, 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29773961/an-example-of-aerosol-pattern-variability-over-bright-surface-using-high-resolution-modis-maiac-the-eastern-and-western-areas-of-the-dead-sea-and-environs
#2
Sever Lee, Alpert Pinhas, Lyapustin Alexei, Wang Yujie, Chudnovsky A Alexandra
The extreme rate of evaporation of the Dead Sea (DS) has serious implicatios for the surrounding area, including atmospheric conditions. This study analyzes the aerosol properties over the western and eastern parts of the DS during the year 2013, using MAIAC (Multi-Angle Implementation of Atmospheric Correction) for MODIS, which retrieves aerosol optical depth (AOD) data at a resolution of 1km. The main goal of the study is to evaluate MAIAC over the study area and determine, for the first time, the prevailing aerosol spatial patterns...
September 2017: Atmospheric Environment
https://www.readbyqxmd.com/read/29772915/a-comparison-of-the-antifouling-performance-of-air-plasma-spray-aps-ceramic-and-high-velocity-oxygen-fuel-hvof-coatings-for-use-in-marine-hydraulic-applications
#3
Richard Piola, Andrew S M Ang, Matthew Leigh, Scott A Wade
Maritime hydraulic components are often exposed to harsh environmental conditions which can lead to accelerated deterioration, reduced function, equipment failure and costly repair. Two leading causes of maritime hydraulic failure are biofouling accumulation and corrosion. This study examined the antifouling performance of three candidate replacement high velocity oxygen fuel (HVOF) coatings relative to the performance of the current baseline air plasma spray (APS) ceramic coating for protection of hydraulic actuators...
May 18, 2018: Biofouling
https://www.readbyqxmd.com/read/29772888/mapping-malaria-risk-using-geographic-information-systems-and-remote-sensing-the-case-of-bahir-dar-city-ethiopia
#4
Amare Sewnet Minale, Kalkidan Alemu
The main objective of this study was to develop a malaria risk map for Bahir Dar City, Amhara, which is situated south of Lake Tana on the Ethiopian plateau. Rainfall, temperature, altitude, slope and land use/land cover (LULC), as well as proximity measures to lake, river and health facilities, were investigated using remote sensing and geographical information systems. The LULC variable was derived from a 2012 SPOT satellite image by supervised classification, while 30-m spatial resolution measurements of altitude and slope came from the Shuttle Radar Topography Mission...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29772175/systematic-excited-state-studies-of-reversibly-switchable-fluorescent-proteins
#5
Daryna Smyrnova, María Del Carmen Marín, Massimo Olivucci, Arnout Ceulemans
A set formed by five reversibly-switchable fluorescent proteins (RSFPs) display spread over 40~nm in absorption maxima and only 18~nm in emission. The five proteins -- Dronpa, rsFastLime, rsKame, Padron(anionic form) and bsDronpa -- carry exactly the same chromophore and differ just in a few mutations. Thus they form an ideal set for mechanistic investigation. Starting with the results of molecular dynamics simulations we use QM/MM calculations to investigate the effects controlling the spectral tuning . In this contribution we show that the models, which are based on CASPT2//CASSCF level of QM theory, reproduce the observed absorption trend with only a limited blue-shift of 4...
May 17, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29771636/subcellular-topography-modulates-actin-dynamics-and-signaling-in-b-cells
#6
Christina M Ketchum, Xiaoyu Sun, Alexandra Suberi, John T Fourkas, Wenxia Song, Arpita Upadhyaya
B cell signaling activation is most effectively triggered by the binding of B cell receptors (BCRs) to membrane-bound antigens.  In vivo, B cells encounter antigen on antigen presenting cells (APC), which possess complex surfaces with convoluted topographies, a fluid membrane and deformable cell bodies. However, whether and how the physical properties of antigen presentation affect B cell activation is not well understood. Here, we use nanotopographic surfaces that allow systematic variation of geometric parameters to show that surface features on a subcellular scale influence B cell signaling and actin dynamics...
May 17, 2018: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/29770491/customised-spectacles-using-3-d-printing-technology
#7
Onder Ayyildiz
BACKGROUND: This study describes a novel method of customised spectacles prototyping and manufacturing using 3-D printing technology. METHODS: The procedure for manufacturing customised spectacles using 3-D printing technology in this study involved five steps: patient selection; using surface topography; 3-D printing of the phantom model; 3-D designing of the spectacles; and 3-D printing of the spectacles. RESULTS: The effective time required for 3-D printing of the spectacles was 14 hours...
May 16, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29770273/westwards-and-northwards-dispersal-of-triosteum-himalayanum-caprifoliaceae-from-the-hengduan-mountains-region-based-on-chloroplast-dna-phylogeography
#8
Hai-Rui Liu, Qing-Bo Gao, Fa-Qi Zhang, Gulzar Khan, Shi-Long Chen
The varying topography and environment that resulted from paleoorogeny and climate fluctuations of the Himalaya-Hengduan Mountains (HHM) areas had a considerable impact on the evolution of biota during the Quaternary. To understand the phylogeographic pattern and historical dynamics of Triosteum himalayanum (Caprifoliaceae), we sequenced three chloroplast DNA fragments ( rbcL-accD , rps15-ycf1 , and trnH-psbA ) from 238 individuals representing 20 populations. Nineteen haplotypes (H1-H19) were identified based on 23 single-site mutations and eight indels...
2018: PeerJ
https://www.readbyqxmd.com/read/29769543/the-cytokine-secretion-profile-of-mesenchymal-stromal-cells-is-determined-by-surface-structure-of-the-microenvironment
#9
Daniëlle G Leuning, Nick R M Beijer, Nadia A du Fossé, Steven Vermeulen, Ellen Lievers, Cees van Kooten, Ton J Rabelink, Jan de Boer
Mesenchymal stromal cells (MSC) secrete factors that contribute to organ homeostasis and repair in a tissue specific manner. For instance, kidney perivascular mesenchymal stromal cells (kPSCs) can facilitate renal epithelial repair through secretion of hepatocyte growth factor (HGF) while the secretome of bone marrow MSCs gives rise to immunosuppression. Stromal cells function in a complex 3-dimensional (3D) connective tissue architecture that induces conformational adaptation. Here we tested the hypothesis that surface topography and associated cell adaptations dictate stromal cell function through tuning of the cytokines released...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29767348/-dynamic-scheimpflug-analyzer-corvis-st-for-measurement-of-corneal-biomechanical-parameters-a-praxis-related-overview
#10
REVIEW
R Herber, N Terai, K R Pillunat, F Raiskup, L E Pillunat, E Spörl
BACKGROUND: Topographic and tomographic parameters alone are often not sufficient for early detection of corneal changes. Pathological alterations in the microstructure of the cornea occur before changes in topography and tomography can be detected. Biomechanical parameters show a strong correlation with microscopic structural changes. OBJECTIVE: The aim of the study was to gain information about the microscopic structure and consistency of the cornea by measuring biomechanical parameters...
May 16, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29766589/dna-aggregation-induced-by-mg-2-ions-under-different-conditions
#11
REVIEW
Van-Chien Bui, Thi-Huong Nguyen
Cations-induced DNA aggregation can modify the local structure of oligonucleotides and has potential applications in medicine and biotechnology. Here, we used atomic force microscopy to investigate λ-DNA aggregation on Mg2+ -treated glass (Mg2+ /glass) and in Mg2+ solution. Atomic force microscopy topography images showed that some DNA fragments were slightly stacked together on 10 mM Mg2+ /glass and stacked stronger on ≥50 mM Mg2+ /glass. They also showed that DNA aggregated stronger in Mg2+ solution than on Mg2+ /glass, ie, DNAs are strongly stacked and twisted at 10 mM Mg2+ , rolled together at 50 mM Mg2+ , and slightly aggregated to form small particles at 100 mM Mg2+ ...
May 15, 2018: Journal of Molecular Recognition: JMR
https://www.readbyqxmd.com/read/29765941/nano-and-micro-patterned-s-h-and-x-pdms-for-cell-based-applications-comparison-of-wettability-roughness-and-cell-derived-parameters
#12
Marina Scharin-Mehlmann, Aaron Häring, Mathias Rommel, Tobias Dirnecker, Oliver Friedrich, Lothar Frey, Daniel F Gilbert
Polydimethylsiloxane (PDMS) is a promising biomaterial for generating artificial extracellular matrix (ECM) like patterned topographies, yet its hydrophobic nature limits its applicability to cell-based approaches. Although plasma treatment can enhance the wettability of PDMS, the surface is known to recover its hydrophobicity within a few hours after exposure to air. To investigate the capability of a novel PDMS-type (X-PDMS) for in vitro based assessment of physiological cell properties, we designed and fabricated plane as well as nano- and micrometer-scaled pillar-patterned growth substrates using the elastomer types S-, H- and X-PDMS, which were fabricated from commercially available components...
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29765476/developmental-trends-of-theta-beta-interelectrode-power-correlation-during-resting-state-in-normal-children
#13
Ernesto Buiza, Elena I Rodríguez-Martínez, Catarina I Barriga-Paulino, Antonio Arjona, Carlos M Gómez
The possibility that power-to-power (theta-beta) frequency coupling increases during development was analyzed. Three minutes of spontaneous EEG in an open eyes condition were recorded in a sample of 160 subjects ranging from 6 to 26 years old. Theta (4-7 Hz) and beta band (15-20 Hz) power was calculated in a trial-by-trial basis. Inter-electrode power correlations (IPC) were computed in each subject as the correlation between the power of two frequency bands recorded in two electrodes. An increase in theta-beta IPC with age was obtained...
June 2018: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29764301/bioinspired-biocompatible-and-peptide-decorated-silk-fibroin-coatings-for-enhanced-osteogenesis-of-bioinert-implant
#14
Chunyan Wang, Shengnan Wang, Yuanyi Yang, Zhuo Jiang, Yi Deng, Shaoli Song, Weizhong Yang, Zhi-Gang Chen
In this study, we develop an osteopromotive polyetheretherketone (PEEK) implant decorated with silk fibroin and bone forming peptide, in which the surface of bioinert PEEK implant is firstly sulfonated to form a three-dimensional, porous topography and then is functionalized with silk fibroin via spin-coating process and peptide decoration. The bio-test results show that cells on the functional bioinert implants exhibit better cell adhesion, proliferation and spreading, when compared with the uncoated ones...
May 15, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29763971/evaluation-of-the-effects-of-the-solution-used-for-electrochemical-dissolution-of-nickel-titanium-endodontic-files-on-dentine-structure-microhardness-and-cell-viability
#15
C C F Amaral, F Ormiga, L C Boldrini, P G Miranda, T A Mendonça, J M Granjeiro, J A C P Gomes
AIM: To evaluate the effects of the [NaF 12 g/L + NaCl 1 g/L] solution used in the electrochemical dissolution process of fractured endodontic files, as well as its NiTi-containing product, on dentine hardness, topography and human fibroblast viability. METHODOLOGY: Sixty single-rooted human teeth were evaluated for dentine microhardness using the Vickers hardness test and the area and number of dentinal tubules by scanning electron microscopy. The samples were divided according to the dentine surface treatment: distilled water; 17% EDTA; [NaF 12 g/L + NaCl 1 g/L]; and 17% EDTA + [NaF 12 g/L + NaCl 1 g/L]...
May 15, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29762544/femtosecond-laser-texturing-of-surfaces-for-tribological-applications
#16
Jörn Bonse, Sabrina V Kirner, Michael Griepentrog, Dirk Spaltmann, Jörg Krüger
Laser texturing is an emerging technology for generating surface functionalities on basis of optical, mechanical, or chemical properties. Taking benefit of laser sources with ultrashort (fs) pulse durations features outstanding precision of machining and negligible rims or burrs surrounding the laser-irradiation zone. Consequently, additional mechanical or chemical post-processing steps are usually not required for fs-laser surface texturing (fs-LST). This work aimed to provide a bridge between research in the field of tribology and laser materials processing...
May 15, 2018: Materials
https://www.readbyqxmd.com/read/29760887/distribution-of-alien-animal-species-richness-in-the-czech-republic
#17
Radek Gebauer, Jan Divíšek, Miloš Buřič, Martin Večeřa, Antonín Kouba, Bořek Drozd
Biogeographical barriers formed by natural forces over billions of years have been substantially disrupted by human activity, particularly in recent centuries. In response to these anthropogenic changes, global homogenization of biota is observed at an ever-increasing rate, causing environmental and economic losses as well as emerging health risks. Identifying factors underlying alien species richness is essential for prevention of future introductions and subsequent spread. In this study, we examined the effects of environmental and human-related factors on distribution of alien animal species richness in the Czech Republic (Central Europe)...
May 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29760886/geographic-variation-in-body-size-and-its-relationship-with-environmental-gradients-in-the-oriental-garden-lizard-calotes-versicolor
#18
Xiaomei Wei, Linmiao Yan, Chengjian Zhao, Yueyun Zhang, Yongli Xu, Bo Cai, Ni Jiang, Yong Huang
Patterns of geographic variation in body size are predicted to evolve as adaptations to local environmental gradients. However, many of these clinal patterns in body size, such as Bergmann's rule, are controversial and require further investigation into ectotherms such as reptiles on a regional scale. To examine the environmental variables (temperature, precipitation, topography and primary productivity) that shaped patterns of geographic variation in body size in the reptile Calotes versicolor , we sampled 180 adult specimens (91 males and 89 females) at 40 locations across the species range in China...
May 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29756205/retrospective-analysis-of-changes-in-response-topographies-of-escape-maintained-aggressive-behavior-during-functional-analyses
#19
Varsovia Hernández, Jonathan K Fernand, Timothy R Vollmer, Sarah K Slocum
We observed changes in the rates of response topographies during the demand condition of functional analyses for participants who demonstrated problem behavior maintained by escape. Over the course of the functional analysis for each participant, the number of topographies decreased from the first to the last session. Additionally, after the first session of the demand condition the rate of responding for one topography increased or remained at high levels while the rates of all other topographies decreased...
May 13, 2018: Journal of Applied Behavior Analysis
https://www.readbyqxmd.com/read/29755816/does-dry-eye-affect-repeatability-of-corneal-topography-measurements
#20
Aysun Şanal Doğan, Canan Gürdal, Mehmet Talay Köylü
Objectives: The purpose of this study was to assess the repeatability of corneal topography measurements in dry eye patients and healthy controls. Materials and Methods: Participants underwent consecutive corneal topography measurements (Sirius; Costruzione Strumenti Oftalmici, Florence, Italy). Two images with acquisition quality higher than 90% were accepted. The following parameters were evaluated: minimum and central corneal thickness, aqueous depth, apex curvature, anterior chamber volume, horizontal anterior chamber diameter, iridocorneal angle, cornea volume, and average simulated keratometry...
April 2018: Turkish Journal of Ophthalmology
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