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Hearing Preservation

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https://www.readbyqxmd.com/read/29775147/intraoperative-cochlear-nerve-mapping-with-the-mobile-cochlear-nerve-compound-action-potential-tracer-in-vestibular-schwannoma-surgery
#1
Nobuyuki Watanabe, Takuya Ishii, Kazuhiko Fujitsu, Shogo Kaku, Teruo Ichikawa, Kosuke Miyahara, Tomu Okada, Shin Tanino, Yasuhiro Uriu, Yuichi Murayama
OBJECTIVE The authors describe the usefulness and limitations of the cochlear nerve compound action potential (CNAP) mobile tracer (MCT) that they developed to aid in cochlear nerve mapping during vestibular schwannoma surgery (VSS) for hearing preservation. METHODS This MCT device requires no more than 2 seconds for stable placement on the nerve to obtain the CNAP and thus is able to trace the cochlear nerve instantaneously. Simultaneous bipolar and monopolar recording is possible. The authors present the outcomes of 18 consecutive patients who underwent preoperative useful hearing (defined as class I or II of the Gardner-Robertson classification system) and underwent hearing-preservation VSS with the use of the MCT...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29773417/stapes-surgery-preserving-the-superstructure-of-stapes-takagi-s-stapedotomy-in-otosclerosis-a-retrospective-study-of-24-consecutive-cases
#2
Shin-Ichi Sato, Akira Takagi, Takashi Fujiwara
OBJECTIVE: The aim of this study was to evaluate the hearing outcomes and complications of stapedotomy in which the stapes superstructure was preserved (Takagi's stapedotomy). In this surgical approach, the lenticular process of the incus rather is removed, than the superstructure of the stapes. METHODS: A single-center retrospective observational study was performed. We included all patients having Takagi's stapedotomy for otosclerosis between January 2005 and April 2016...
May 14, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29764773/cochlear-implant-electrode-array-from-partial-to-full-insertion-in-non-human-primate-model
#3
Raquel Manrique-Huarte, Diego Calavia, Maria Antonia Gallego, Manuel Manrique
OBJECTIVES: To determine the feasibility of progressive insertion (two sequential surgeries: partial to full insertion) of an electrode array and to compare functional outcomes. MATERIAL AND METHODS: 8 normal-hearing animals (Macaca fascicularis (MF)) were included. A 14 contact electrode array, which is suitably sized for the MF cochlea was partially inserted (PI) in 16 ears. After 3 months of follow-up revision surgery the electrode was advanced to a full insertion (FI) in 8 ears...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29761349/intracochlear-administration-of-steroids-with-a-catheter-during-human-cochlear-implantation-a-safety-and-feasibility-study
#4
Nils K Prenzler, Rolf Salcher, Max Timm, Lutz Gaertner, Thomas Lenarz, Athanasia Warnecke
Suppression of foreign body reaction, improvement of electrode-nerve interaction, and preservation of residual hearing are essential research topics in cochlear implantation. Intracochlear pharmaco- or cell-based therapies can open new horizons in this field. Local drug delivery strategies are desirable as higher local concentrations of agents can be realized and side effects can be minimized compared to systemic administrations. When administered locally at accessible, basal parts of the cochlea, drugs reach apical regions later and in much lower concentrations due to poor diffusion patterns in cochlear fluids...
May 14, 2018: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/29756616/treatment-of-cholesteatoma-with-intact-ossicular-chain-anatomic-and-functional-results
#5
V Pontillo, F Barbara, V DE Robertis, N Quaranta
In case of cholesteatoma with intact ossicular chain, the primary aims of surgery are complete removal of the cholesteatoma matrix and reconstruction of a dry and safe middle ear; if possible, ossicular chain continuity and therefore the preoperative hearing must be preserved. The aim of this retrospective study is to present the experience of the U.O.C. Otorinolaringoiatria Universitaria of University of Bari "Aldo Moro" in treatment of intact ossicular chain cholesteatoma with Bondy modified radical mastoidectomy (BMRM) and canal wall up tympanoplasty (CWUT)...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29756611/cochlear-obliteration-following-a-translabyrinthine-approach-and-its-implications-in-cochlear-implantation
#6
B Delgado-Vargas, M Medina, R Polo, A Lloris, M Vaca, C Pérez, A Cordero, I Cobeta
The most frequent sequelae following a translabyrinthine approach for vestibular schwannoma resection is complete hearing loss on the affected side. Such patients could benefit from a cochlear implant, provided that two essential requisites are met before surgery: a preserved cochlear nerve and a patent cochlea to accommodate the electrode array. The goal of our study is to determine the prevalence and extent of cochlear ossification following a translabyrinthine approach. Postoperative MRI of 41 patients were retrospectively reviewed...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29750273/video-head-impulse-test-to-preoperatively-identify-the-nerve-of-origin-of-vestibular-schwannomas
#7
Felipe Constanzo, Patricia Sens, Bernardo Corrêa de Almeida Teixeira, Ricardo Ramina
BACKGROUND: Identification of the nerve of origin in vestibular schwannoma (VS) is an important prognostic factor for hearing preservation surgery. Thus far, vestibular functional tests and magnetic resonance imaging have not yielded reliable results to preoperatively evaluate this information. The development of the video head impulse test (vHIT) has allowed a precise evaluation of each semicircular canal, and its localizing value has been tested for some peripheral vestibular diseases, but not for VS...
May 10, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29748054/functional-and-anatomical-outcome-of-inside-out-technique-for-cholesteatoma-surgery
#8
Priyanka Chamoli, Chandra Veer Singh, Sheetal Radia, Anand K Shah
BACKGROUND: To study the efficacy of inside-out technique in completely eradicating the cholesteatoma from middle ear and mastoid, preservation of hearing & and quality of life post mastoidectomy with regards to recurrent discharge, wax, granulations. MATERIAL AND METHODS: Non-randomized, prospective, observational study performed at the Department of ENT in our hospital. In the study we included 100 patients presenting with chronic suppurative otitis media with cholesteatoma, they underwent inside out mastoidectomy and were followed up till the end of the study to evaluate the efficacy of inside out mastoidectomy in eradicating the disease from the middle ear cleft...
April 17, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29747962/comparison-of-vemps-vhit-and-caloric-test-outcomes-after-vestibular-neurectomy-in-meni%C3%A3-re-s-disease
#9
Andrea Canale, Federico Caranzano, Michele Lanotte, Alessandro Ducati, Francesco Calamo, Andrea Albera, Michelangelo Lacilla, Marco Boldreghini, Sergio Lucisano, Roberto Albera
OBJECTIVE: Selective unilateral vestibular neurectomy (VN) is considered a reliable surgical treatment in case of recurrent vertigo in Menière's disease (MD) because of hearing preservation and a minimally invasive posterior fossa retrosigmoid approach. The present study aimed to assess the quality of life and the long-term vestibular function in patients submitted to yearly follow-up after VN because of intractable MD. METHODS: Retrospective series of 15 MD patients undergoing retrosigmoid VN for recurrent vertigo...
May 7, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29744731/factors-affecting-speech-reception-in-background-noise-with-a-vocoder-implementation-of-the-fast-algorithm
#10
Shaikat Hossain, Raymond L Goldsworthy
Speech segregation in background noise remains a difficult task for individuals with hearing loss. Several signal processing strategies have been developed to improve the efficacy of hearing assistive technologies in complex listening environments. The present study measured speech reception thresholds in normal-hearing listeners attending to a vocoder based on the Fundamental Asynchronous Stimulus Timing algorithm (FAST: Smith et al. 2014), which triggers pulses based on the amplitudes of channel magnitudes in order to preserve envelope timing cues, with two different reconstruction bandwidths (narrowband and broadband) to control the degree of spectrotemporal resolution...
May 9, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29728102/stenting-the-eustachian-tube-to-treat-chronic-otitis-media-a-feasibility-study-in-sheep
#11
Friederike Pohl, Robert A Schuon, Felicitas Miller, Andreas Kampmann, Eva Bültmann, Christian Hartmann, Thomas Lenarz, Gerrit Paasche
BACKGROUND: Untreated chronic otitis media severely impairs quality of life in affected individuals. Local destruction of the middle ear and subsequent loss of hearing are common sequelae, and currently available treatments provide limited relief. Therefore, the objectives of this study were to evaluate the feasibility of the insertion of a coronary stent from the nasopharynx into the Eustachian tube in-vivo in sheep and to make an initial assessment of its positional stability, tolerance by the animal, and possible tissue reactions...
May 4, 2018: Head & Face Medicine
https://www.readbyqxmd.com/read/29710020/-a-15-year-old-girl-with-congenital-cytomegalovirus-infection-presenting-with-sensorineural-hearing-impairment-and-cerebral-while-matter-lesions-but-no-intellectual-disability
#12
Keiichi Nakagawa, Masato Kadoya, Hiroshi Matsumoto, Hiroyuki Moriuchi, Katsunori Ikewaki, Kenichi Kaida
A 15-year-old girl presented with non-progressive sensorineural hearing impairment in her right ear since her early childhood. She had normal intellectual development. When she was 15 years old, small deep white matter lesions around the lateral ventricles were incidentally detected in brain MRI studies through further investigation of auditory organs. Laboratory data including cerebrospinal fluid analysis and antibodies to aquaporin-4 or myelin-oligodendrocyte glycoprotein were normal. She was diagnosed as a congenital cytomegalovirus (CMV) infection based on the detection of CMV DNA from preserved umbilical cord tissue by real-time polymerase chain reaction...
April 28, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29704694/flexible-endoscopic-assisted-microsurgical-radical-resection-of-intracanalicular-vestibular-schwannomas-by-retrosigmoid-approach-operative-technique
#13
Francesco Corrivetti, Guglielmo Cacciotti, Carlo Giacobbo Scavo, Raffaelino Roperto, Luciano Mastronardi
BACKGROUND: s: The efficacy of endoscopic techniques in the surgical management of intracanalicular vestibular schwannomas (ICVS) has been underlined in recent studies. Particularly, endoscopic assisted retrosigmoid approach (EARSA) appears particularly suitable in achieving complete resection of ICVS. OBJECTIVE: In this study we present the surgical treatment of 3 cases of ICVS, treated with an endoscopic assisted retrosigmoid approach, highlighting advantages and limitations of flexible endoscope in the accomplishment of a safe radical resection with hearing preservation...
April 25, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29702972/microsurgery-for-patients-diagnosed-with-neurofibromatosis-type-2-complicated-by-vestibular-schwannomas-clinical-experience-and-strategy-for-treatments
#14
Li-Hua Chen, Hong-Tian Zhang, Ru-Xiang Xu, Li Zhang, Wen-De Li, Kai Sun
Most patients diagnosed with neurofibromatosis type 2 (NF2) have bilateral vestibular schwannomas (VS). Through reviewing surgical method and clinical outcomes, we tried to find out a strategy for treatments in NF2 patients with VS.We retrospectively reviewed patients diagnosed pathological NF2 and have had microsurgery (MS) for VS in the PLA Army General Hospital. Seventeen patients were included from January 2000 to December 2016. Fifteen patients had progressive hearing impairment, and 7 ears were totally deaf...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29701288/cytokine-expression-profile-in-the-bone-anchored-hearing-system-12-week-results-from-a-prospective-randomized-controlled-study
#15
Tim George Ate Calon, Joost van Tongeren, Omar Omar, Martin Lars Johansson, Robert-Jan Stokroos
OBJECTIVE: To study the effect of implanting the percutaneous bone-anchored hearing system (BAHS) itself and inflammation of the peri-abutment skin warrant clarification. In this study, we aimed to acquire further insight into the immune responses related to BAHS surgery and peri-implant skin inflammation. MATERIALS AND METHODS: During surgery and 12 weeks post-implantation, skin biopsies were obtained. If applicable, additional biopsies were taken during cases of inflammation...
April 27, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29687008/secondary-degeneration-of-auditory-neurons-after-topical-aminoglycoside-administration-in-a-gerbil-model
#16
Jae-Hun Lee, Min Young Lee, Phil-Sang Chung, Jae Yun Jung
Hair cells in the cochlea can be damaged by various causes. Damaged hair cells can lead to additional destruction of parts of the auditory afferent pathway sequentially, which is called secondary degeneration. Recently, researches regarding cochlear implants have been actively carried out for clinical purposes; secondary degeneration in animals is a much more practical model for identifying the prognosis of cochlear implants. However, an appropriate model for this research is not established yet. Thus, we developed a secondary degeneration model using an ototoxic drug...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29685378/cochlear-implants-insertion-assessment-by-computed-tomography
#17
Ana Luiza Menegatti Pavan, Allan Felipe Fattori Alves, Guilherme Giacomini, João Maurício Carrasco Altemani, Arthur Menino Castilho, Raquel Andrade Lauria, Vagner Antonio Rodrigues da Silva, Alexandre Caixeta Guimarães, Diana Rodrigues de Pina
BACKGROUND AND OBJECTIVES: Imaging exams play a key role in cochlear implants with regard to both planning implantation before surgery and quality control after surgery. The ability to visualize the three-dimensional location of implanted electrodes is useful in clinical routines for assessing patient outcome. The aim of this study was to evaluate linear and angular insertion depth measurements of cochlear implants based on conventional computed tomography. METHODS: Tools for linear and angular measurements of cochlear implants were used in computed tomography exams...
April 14, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29680860/preservation-of-hearing-following-cochlear-implantation-using-different-steroid-therapy-regimens-a-prospective-clinical-study
#18
Magdalena Beata Skarżyńska, Piotr Henryk Skarżyński, Bartłomiej Król, Magdalena Kozieł, Kamila Osińska, Elżbieta Gos, Henryk Skarżyński
BACKGROUND A prospective clinical study was conducted to assess different regimens of steroid therapy and preservation of hearing following cochlear implantation. MATERIAL AND METHODS Study participants were ≥18 years-of-age, with a cochlear duct length ≥27.1 mm measured by computed tomography (CT), with hearing sound levels in the range of 10-120 decibels (dB) and sound frequencies of 125-250 hertz (Hz); sound levels of 35-120 dB and frequencies of 500-1,000 Hz; sound levels of 75-120 dB and frequencies of 2,000-8,000 Hz...
April 22, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29673835/effects-of-ovarian-reserve-and-hormone-therapy-on-hearing-in-premenopausal-and-postmenopausal-women-a-cross-sectional-study
#19
Jingfei Zhang, Tingyue Zhang, Lisheng Yu, Qianying Ruan, Lingxue Yin, Dong Liu, Haicheng Zhang, Wenpei Bai, Zhenghong Ren
OBJECTIVES: To observe the hearing function around menopause, to analyze the effects of ovarian reserve and hormone therapy on hearing, and to study factors related to hearing loss among women around menopause. STUDY DESIGN: In this cross-sectional study, we evaluated 109 women around menopause aged 45-55 years, including 40 women with ovarian failure, 48 with ovarian non-failure, and 21 receiving hormone therapy. All women underwent an audiologic evaluation, and hormone blood testing was performed...
May 2018: Maturitas
https://www.readbyqxmd.com/read/29673567/electric-acoustic-forward-masking-in-cochlear-implant-users-with-ipsilateral-residual-hearing
#20
Marina Imsiecke, Benjamin Krüger, Andreas Büchner, Thomas Lenarz, Waldo Nogueira
In order to investigate the temporal mechanisms of the auditory system, psychophysical forward masking experiments were conducted in cochlear implant users who had preserved acoustic hearing in the ipsilateral ear. This unique electric-acoustic stimulation (EAS) population allowed the measurement of threshold recovery functions for acoustic or electric probes in the presence of electric or acoustic maskers, respectively. In the electric masking experiment, the forward masked threshold elevation of acoustic probes was measured as a function of the time interval after the offset of the electric masker, i...
April 9, 2018: Hearing Research
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