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Hearing Preservation

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https://www.readbyqxmd.com/read/29342055/benefit-of-preoperative-temporal-bone-ct-for-atraumatic-cochlear-implantation
#1
Alexandre Karkas, Nicolas Menjot de Champfleur, Alain Uziel, Michel Mondain, Jean-Luc Puel, Frédéric Venail
HYPOTHESIS: Evaluate the benefit of preoperative surgical planning using computed tomography (CT) for atraumatic cochlear implantation. BACKGROUND: The surgical technique has a direct impact on hearing and structure preservation. Much interest has been given to depth of electrode insertion. We focused on electrode diameter depending on exposure of round window membrane (RWM) as calculated on preoperative CT. METHODS: Measurements were calculated radiologically and anatomically on 10 temporal bones...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29342037/preservation-of-cells-of-the-organ-of-corti-and-innervating-dendritic-processes-following-cochlear-implantation-in-the-human-an-immunohistochemical-study
#2
Takefumi Kamakura, Jennifer T O'Malley, Joseph B Nadol
HYPOTHESIS: This study evaluates the degree of preservation of hair cells, supporting cells, and innervating dendritic processes after cochlear implantation in the human using immunohistochemical methods. BACKGROUND: Surgical insertion of a cochlear implant electrode induces various pathologic changes within the cochlea including insertional trauma, foreign body response, inflammation, fibrosis, and neo-osteogenesis. These changes may result in loss of residual acoustic hearing, adversely affecting the use of hybrid implants, and may result in loss of putative precursor cells, limiting the success of future regenerative protocols...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29342035/systematic-review-of-hearing-preservation-after-radiotherapy-for-vestibular-schwannoma
#3
Adam R Coughlin, Tyler J Willman, Samuel P Gubbels
OBJECTIVE: To determine the long-term hearing preservation rate for spontaneous vestibular schwannoma treated by primary radiotherapy. DATA SOURCES: The MEDLINE/PubMed, Web of Science, Cochrane Reviews, and EMBASE databases were searched using a comprehensive Boolean keyword search developed in conjunction with a scientific librarian. English language papers published from 2000 to 2016 were evaluated. STUDY SELECTION: Inclusion criteria: full articles, pretreatment and posttreatment audiograms or audiogram based scoring system, vestibular schwannoma only tumor type, reported time to follow-up, published after 1999, use of either Gamma Knife or linear accelerator radiotherapy...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29339512/neural-preservation-underlies-speech-improvement-from-auditory-deprivation-in-young-cochlear-implant-recipients
#4
Gangyi Feng, Erin M Ingvalson, Tina M Grieco-Calub, Megan Y Roberts, Maura E Ryan, Patrick Birmingham, Delilah Burrowes, Nancy M Young, Patrick C M Wong
Although cochlear implantation enables some children to attain age-appropriate speech and language development, communicative delays persist in others, and outcomes are quite variable and difficult to predict, even for children implanted early in life. To understand the neurobiological basis of this variability, we used presurgical neural morphological data obtained from MRI of individual pediatric cochlear implant (CI) candidates implanted younger than 3.5 years to predict variability of their speech-perception improvement after surgery...
January 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29338942/international-consensus-icon-on-treatment-of-m%C3%A3-ni%C3%A3-re-s-disease
#5
J Nevoux, M Barbara, J Dornhoffer, W Gibson, T Kitahara, V Darrouzet
OBJECTIVE: To present the international consensus for recommendations for Ménière's disease (MD) treatment. METHODS: Based on a literature review and report of 4 experts from 4 continents, the recommendations have been presented during the 21st IFOS congress in Paris, in June 2017 and are presented in this work. RESULTS: The recommendation is to change the lifestyle, to use the vestibular rehabilitation in the intercritic period and to propose psychotherapy...
January 12, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29334639/vestibular-schwannoma-and-hearing-preservation-usefulness-of-level-specific-ce-chirp-abr-monitoring-a-retrospective-study-on-25-cases-with-preoperative-socially-useful-hearing
#6
Luciano Mastronardi, Ettore Di Scipio, Guglielmo Cacciotti, Raffaelino Roperto
BACKGROUND AND OBJECTIVES: Decision-making regarding the therapy of vestibular schwannoma (VS) changed over the last decades, during which curative microsurgery has been promoted. Goals of VS microsurgery are: extensive resection, facial nerve (FN) preservation and, in selected cases, hearing preservation (HP). The aim of this study is to evaluate postoperative HP with reference to tumor size in patients operated on with Level Specific (LS)-CE-Chirp® ABR monitoring. PATIENTS AND METHODS: Twentyfive consecutive patients with socially useful hearing (SUH) underwent VS microneurosurgery by retrosigmoid (RS) approach...
January 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29332068/the-role-of-preoperative-steroids-for-hearing-preservation-cochlear-implantation-results-of-a-randomized-controlled-trial
#7
Jafri Kuthubutheen, Samidha Joglekar, Leah Smith, Lendra Friesen, Kari Smilsky, Tara Millman, Amy Ng, David Shipp, Harvey Coates, Christoph Arnoldner, Julian Nedzelski, Joseph Chen, Vincent Lin
OBJECTIVES: To determine whether preoperative steroids can improve hearing outcomes in cochlear implantation (CI). METHODS: This is a randomized controlled trial involving 30 postlingual deaf CI patients. Subjects had preoperative thresholds of better than or equal to 80 dB at 125 and 250 Hz, and better than or equal to 90 dB at 500 and 1,000 Hz. The subjects were randomized to a control group, an oral steroid group (receiving 1 mg/kg/day of prednisolone for 6 days prior to surgery), or a transtympanic steroid group (receiving a single dose of 0...
January 13, 2018: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/29327735/acquired-sensorineural-hearing-loss-in-children-current-research-and-therapeutic-perspectives
#8
M Ralli, R Rolesi, R Anzivino, R Turchetta, A R Fetoni
The knowledge of mechanisms responsible for acquired sensorineural hearing loss in children, such as viral and bacterial infections, noise exposure, aminoglycoside and cisplatin ototoxicity, is increasing and progressively changing the clinical management of affected patients. Viral infections are by far the most relevant cause of acquired hearing loss, followed by aminoglycoside and platinum derivative ototoxicity; moreover, cochlear damage induced by noise overexposure, mainly in adolescents, is an emerging topic...
December 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29315192/long-term-hearing-preservation-outcomes-for-small-vestibular-schwannomas-retrosigmoid-removal-versus-observation
#9
Weidong Zhu, Hongsai Chen, Huan Jia, Yongchuan Chai, Jie Yang, Zhaoyan Wang, Hao Wu
OBJECTIVE: Management of small vestibular schwannomas (VSs) consists of three options: serial observation, radiosurgery, and microsurgery. The authors reported the long-term hearing outcomes after retrosigmoid tumor removal in 110 patients and hearing follow-up outcomes in 160 serial observation patients with small VSs to explore the appropriate management strategy and predictive factors of hearing preservation for small VSs. STUDY DESIGN: Retrospective study. SETTING: Tertiary referral center...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29315191/ultra-long-term-audiometric-outcomes-in-the-treatment-of-vestibular-schwannoma-with-the-middle-cranial-fossa-approach
#10
Joseph P Roche, Erika A Woodson, Marlan R Hansen, Bruce J Gantz
OBJECTIVE: Define the long-term audiometric outcomes of vestibular schwannomas treated using the middle cranial fossa (MCF) approach. STUDY DESIGN: Retrospective records review. SETTING: University-based tertiary referral center. PATIENTS: Patients undergoing treatment of small vestibular schwannomas using the MCF approach. INTERVENTION(S): MCF exposure and treatment of small vestibular schwannomas...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29315190/audiological-outcomes-in-growing-vestibular-schwannomas-managed-either-conservatively-or-with-stereotactic-radiosurgery
#11
Thomas Daniel Milner, Richard R Locke, Georgios Kontorinis, John A Crowther
OBJECTIVE: Recent studies have suggested good hearing preservation following stereotactic radiosurgery (STRS) in patients with vestibular schwannomas (VS). This study aims to assess audiological outcomes in patients with growing VS treated either with STRS, or managed conservatively. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary referral center. PATIENTS: Out of 540 patients with VS, 69 patients with growing VS fulfilled the inclusion criteria; 24 treated conservatively and 45 with STRS...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29305691/the-capos-mutation-in-atp1a3-alters-na-k-atpase-function-and-results-in-auditory-neuropathy-which-has-implications-for-management
#12
Lisbeth Tranebjærg, Nicola Strenzke, Sture Lindholm, Nanna D Rendtorff, Hanne Poulsen, Himanshu Khandelia, Wojciech Kopec, Troels J Brünnich Lyngbye, Christian Hamel, Cecile Delettre, Beatrice Bocquet, Michael Bille, Hanne H Owen, Toke Bek, Hanne Jensen, Karen Østergaard, Claes Möller, Linda Luxon, Lucinda Carr, Louise Wilson, Kaukab Rajput, Tony Sirimanna, Katherine Harrop-Griffiths, Shamima Rahman, Barbara Vona, Julia Doll, Thomas Haaf, Oliver Bartsch, Hendrik Rosewich, Tobias Moser, Maria Bitner-Glindzicz
Cerebellar ataxia, areflexia, pes cavus, optic atrophy and sensorineural hearing impairment (CAPOS) is a rare clinically distinct syndrome caused by a single dominant missense mutation, c.2452G>A, p.Glu818Lys, in ATP1A3, encoding the neuron-specific alpha subunit of the Na+/K+-ATPase α3. Allelic mutations cause the neurological diseases rapid dystonia Parkinsonism and alternating hemiplegia of childhood, disorders which do not encompass hearing or visual impairment. We present detailed clinical phenotypic information in 18 genetically confirmed patients from 11 families (10 previously unreported) from Denmark, Sweden, UK and Germany indicating a specific type of hearing impairment-auditory neuropathy (AN)...
January 5, 2018: Human Genetics
https://www.readbyqxmd.com/read/29298539/cholesteatoma-surgery-with-the-canal-wall-up-technique-combined-with-mastoid-obliteration-results-from-primary-surgery-in-230-consecutive-cases
#13
Johanna Westerberg, Elina Mäki-Torkko, Henrik Harder
OBJECTIVE: To evaluate the canal wall up (CWU) technique combined with mastoid obliteration used in cholesteatoma surgery from the aspects of safety and function. STUDY DESIGN: Retrospective chart review. Information was extracted from a medical database and complementary data from patient files and audiograms were collected and recorded retrospectively. SETTING: A tertiary-stage hospital and a secondary-stage hospital. Surgeons of various levels of experience...
January 3, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29279723/diagnostics-and-therapy-of-vestibular-schwannomas-an-interdisciplinary-challenge
#14
REVIEW
Steffen Rosahl, Christopher Bohr, Michael Lell, Klaus Hamm, Heinrich Iro
Vestibular schwannomas (VS) expand slowly in the internal auditory canal, in the cerebellopontine angle, inside the cochlear and the labyrinth. Larger tumors can displace and compress the brainstem. With an annual incidence of 1:100,000 vestibular schwannoma represent 6-7% of all intracranial tumors. In the cerebellopontine angle they are by far the most neoplasm with 90% of all lesions located in this region. Magnetic resonance imaging (MRI), audiometry, and vestibular diagnostics are the mainstays of the clinical workup for patients harboring tumors...
2017: GMS Current Topics in Otorhinolaryngology, Head and Neck Surgery
https://www.readbyqxmd.com/read/29273266/in-vitro-and-in-vivo-measurement-of-the-animal-s-middle-ear-acoustical-response-by-partially-implantable-fiber-optic-sensing-system
#15
Zoran Djinović, Robert Pavelka, Miloš Tomić, Georg Sprinzl, Hanns Plenk, Udo Losert, Helga Bergmeister, Roberto Plasenzotti
The main obstacle in realization of a totally implantable hearing aid is a lack of reliable implantable microphone. In this paper we have described a potentially miniature fiber-optic vibrometer based on a modified Michelson interferometer, designed to serve as a middle-ear microphone for totally implantable cochlear- or middle-ear hearing aids. A model of the sensing system was used for in-vitro and in-vivo investigation of acoustical response of sheep's middle-ear ossicles. Surgical and implantation procedure of introducing the sensing optical fiber into the middle-ear and its aiming at the incus was investigated and described here in detail...
December 10, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29251689/the-summating-potential-is-a-reliable-marker-of-electrode-position-in-electrocochleography-cochlear-implant-as-a-theragnostic-probe
#16
Victor Helmstaedter, Thomas Lenarz, Peter Erfurt, Andrej Kral, Peter Baumhoff
OBJECTIVE: For the increasing number of cochlear implantations in subjects with residual hearing, hearing preservation, and thus the prevention of implantation trauma, is crucial. A method for monitoring the intracochlear position of a cochlear implant (CI) and early indication of imminent cochlear trauma would help to assist the surgeon to achieve this goal. The aim of this study was to evaluate the reliability of the different electric components recorded by an intracochlear electrocochleography (ECochG) as markers for the cochleotopic position of a CI...
December 14, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/29240567/theoretical-evaluation-and-experimental-validation-of-localized-therapeutic-hypothermia-application-to-preserve-residual-hearing-after-cochlear-implantation
#17
Ilmar Tamames, Curtis King, Chin-Yuh Huang, Fred F Telischi, Michael E Hoffer, Suhrud M Rajguru
OBJECTIVES: Cochlear implantation surgery has been shown to result in trauma to inner ear sensory structures, resulting in loss of residual hearing. Localized therapeutic hypothermia has been shown in clinical care to be a neuroprotective intervention. Previously, we have shown in an experimental model that localized hypothermia protects cochlear hair cells and residual hearing function against surgical and cochlear implantation trauma. Using experimental temperature measurements carried out in human cadaver temporal bones and a finite element model of the inner ear, the present study examined the temperature distribution of a custom-designed hypothermia delivery system in the human inner ear organs...
December 13, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/29227454/immediate-and-long-term-hearing-outcomes-with-the-middle-cranial-fossa-approach-for-vestibular-schwannoma-resection
#18
Sameer Ahmed, H Alexander Arts, Hussam El-Kashlan, Gregory J Basura, B Gregory Thompson, Steven A Telian
OBJECTIVE: To analyze the immediate postoperative and long-term hearing outcome data in patients who have undergone hearing preservation attempts with the middle cranial fossa (MCF) approach for the resection of sporadic vestibular schwannoma. STUDY DESIGN: Retrospective review of a surgical patient cohort. SETTING: Tertiary academic referral center. PATIENTS: Adult patients with unilateral sporadic vestibular schwannoma...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29227449/early-outcomes-with-a-slim-modiolar-cochlear-implant-electrode-array
#19
Jonathan L McJunkin, Nedim Durakovic, Jacques Herzog, Craig A Buchman
OBJECTIVE: To describe outcomes from cochlear implantation with a new, slim modiolar electrode array. STUDY DESIGN: Retrospective cohort study. SETTING: Tertiary referral centers. PATIENTS: Adult cochlear implant candidates. INTERVENTIONS: Cochlear implantation with CI532 (Cochlear Corp). MAIN OUTCOME MEASURES: Pre- and postoperative speech perception scores, operative details, and postoperative computed tomography (CT) reconstructions of array location...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29227447/heat-shock-proteins-in-human-perilymph-implications-for-cochlear-implantation
#20
Heike Schmitt, Ariane Roemer, Carsten Zeilinger, Rolf Salcher, Martin Durisin, Hinrich Staecker, Thomas Lenarz, Athanasia Warnecke
OBJECTIVE: Biomarkers reflecting the etiology and pathophysiology of inner ear diseases are limited. Evaluation of proteins in the perilymph may improve our understanding of inner ear disease. Heat shock proteins (HSP) belong to a superfamily of stress proteins and promote refolding of denatured proteins. The aim of the study was to analyze HSP in human perilymph and to identify possible correlation with audiological and etiologic data. METHODS: Sampling of the perilymph was performed during cochlear implantation and vestibular schwannoma removal...
January 2018: Otology & Neurotology
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