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Hearing Preservation

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https://www.readbyqxmd.com/read/27928625/stereotactic-radiotherapy-of-vestibular-schwannoma-hearing-preservation-vestibular-function-and-local-control-following-primary-and-salvage-radiotherapy
#1
Florian Putz, Jan Müller, Caterina Wimmer, Nicole Goerig, Stefan Knippen, Heinrich Iro, Philipp Grundtner, Ilker Eyüpoglu, Karl Rössler, Sabine Semrau, Rainer Fietkau, Sebastian Lettmaier
OBJECTIVE: The aim of this publication is to present long-term data on functional outcomes and tumor control in a cohort of 107 patients treated with stereotactic radiotherapy (RT) for vestibular schwannoma. PATIENTS AND METHODS: Included were 107 patients with vestibular schwannoma (primary or recurrent following resection) treated with stereotactic RT (either fractioned or single-dose radiosurgery) between October 2002 and December 2013. Local control and functional outcomes were determined...
December 7, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27918363/tip-fold-over-in-cochlear-implantation-case-series
#2
M Geraldine Zuniga, Alejandro Rivas, Andrea Hedley-Williams, Rene H Gifford, Robert Dwyer, Benoit M Dawant, Linsey W Sunderhaus, Kristen L Hovis, George B Wanna, Jack H Noble, Robert F Labadie
OBJECTIVE: To describe the incidence, clinical presentation, and performance of cochlear implant (CI) recipients with tip fold-over. STUDY DESIGN: Retrospective case series. SETTING: Tertiary referral center. PATIENTS: CI recipients who underwent postoperative computed tomography (CT) scanning. INTERVENTION(S): Tip fold-over was identified tomographically using previously validated software that identifies the electrode array...
December 1, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27918225/clinical-surgical-and-electrical-factors-impacting-residual-hearing-in-cochlear-implant-surgery
#3
Adrien A Eshraghi, Jamal Ahmed, Eric Krysiak, Kadri Ila, Peter Ashman, Fred F Telischi, Simon Angeli, Sandra Prentiss, Diane Martinez, Sandra Valendia
CONCLUSIONS: This study recommends using soft surgical principal and round window insertion to protect residual hearing with favorable anatomical exposure. Further studies are needed to evaluate the impact of the electrical stimulation on the organ of corti and hearing. OBJECTIVE: The objective of this study is to analyze various factors that impact on preservation of residual hearing post-implantation. METHODS: A retrospective study was performed to analyze loss of residual hearing in a cohort of 225 patients implanted in a large academic center...
December 5, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27914381/modulation-masking-and-glimpsing-of-natural-and-vocoded-speech-during-single-talker-modulated-noise-effect-of-the-modulation-spectrum
#4
Daniel Fogerty, Jiaqian Xu, Bobby E Gibbs
Compared to notionally steady-state noise, modulated maskers provide a perceptual benefit for speech recognition, in part due to preserved speech information during the amplitude dips of the masker. However, overlap in the modulation spectrum between the target speech and the competing modulated masker may potentially result in modulation masking, and thereby offset the release from energetic masking. The current study investigated masking release provided by single-talker modulated noise. The overlap in the modulation spectra of the target speech and the modulated noise masker was varied through time compression or expansion of the competing masker...
September 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27913265/hearing-preservation-during-anterior-petrosectomy-the-cochlear-safety-line
#5
Xiaoming Guo, Halima Tabani, Dylan Griswold, Ali Tayebi Meybodi, Jose Juan Gonzalez Sanchez, Michael T Lawton, Arnau Benet
BACKGROUND: Identification and protection of the cochlea during anterior petrosectomy is key to prevent hearing loss. Currently, there is no optimal method to infer the position of the cochlea in relation to the Kawase quadrangle, therefore damage to the cochlea during anterior petrosectomy remains a substantial risk. OBJECTIVES: To identify and define landmarks available during anterior petrosectomy to locate the cochlea and prevent its damage. METHODS: Kawase approach was simulated in eleven specimens...
November 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27908047/assessing-the-perceptual-contributions-of-level-dependent-segments-to-sentence-intelligibility
#6
Tian Guan, Guang-Xing Chu, Yu Tsao, Fei Chen
The present work assessed the contributions of high root-mean-square (RMS) level (H-level, containing primarily vowels) and middle-RMS-level (M-level, with mostly consonants and vowel-consonant transitions) segments to the intelligibility of noise-masked and noise-suppressed sentences. In experiment 1, noise-masked (by speech-spectrum shaped noise and 6-talker babble) Mandarin sentences were edited to preserve only H- or M-level segments, while replacing the non-target segments with silence. In experiment 2, Mandarin sentences were subjected to four commonly-used single-channel noise-suppression algorithms before generating H-level-only and M-level-only noise-suppressed sentences...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27908030/influences-of-noise-interruption-and-information-bearing-acoustic-changes-on-understanding-simulated-electric-acoustic-speech
#7
Christian Stilp, Gail Donaldson, Soohee Oh, Ying-Yee Kong
In simulations of electrical-acoustic stimulation (EAS), vocoded speech intelligibility is aided by preservation of low-frequency acoustic cues. However, the speech signal is often interrupted in everyday listening conditions, and effects of interruption on hybrid speech intelligibility are poorly understood. Additionally, listeners rely on information-bearing acoustic changes to understand full-spectrum speech (as measured by cochlea-scaled entropy [CSE]) and vocoded speech (CSECI), but how listeners utilize these informational changes to understand EAS speech is unclear...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27903183/stereotactic-radiosurgery-for-vestibular-schwannomas-average-10-year-follow-up-results-focusing-on-long-term-hearing-preservation
#8
Shinya Watanabe, Masaaki Yamamoto, Takuya Kawabe, Takao Koiso, Tetsuya Yamamoto, Akira Matsumura, Hidetoshi Kasuya
OBJECTIVE The aim of this study was to reappraise long-term treatment outcomes of stereotactic radiosurgery (SRS) for vestibular schwannomas (VSs). The authors used a database that included patients who underwent SRS with a unique dose-planning technique, i.e., partial tumor coverage designed to avoid excess irradiation of the facial and cochlear nerves, focusing on tumor control and hearing preservation. Clinical factors associated with post-SRS tumor control and long-term hearing preservation were also analyzed...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27888040/evidence-that-hidden-hearing-loss-underlies-amplitude-modulation-encoding-deficits-in-individuals-with-and-without-tinnitus
#9
Brandon T Paul, Ian C Bruce, Larry E Roberts
Damage to auditory nerve fibers that expresses with suprathreshold sounds but is hidden from the audiogram has been proposed to underlie deficits in temporal coding ability observed among individuals with otherwise normal hearing, and to be present in individuals experiencing chronic tinnitus with clinically normal audiograms. We tested whether these individuals may have hidden synaptic losses on auditory nerve fibers with low spontaneous rates of firing (low-SR fibers) that are important for coding suprathreshold sounds in noise while high-SR fibers determining threshold responses in quiet remain relatively unaffected...
November 23, 2016: Hearing Research
https://www.readbyqxmd.com/read/27885877/surgical-outcomes-of-middle-fossa-approach-in-intracanalicular-vestibular-schwannoma
#10
Woo Seok Kang, Shin Ae Kim, Chan Joo Yang, Sung Hoon Nam, Jong Woo Chung
CONCLUSION: Middle fossa approach (MFA) shows a hearing preservation rate of 86% and facial nerve function was preserved with HB grade I or II in 93%. MFA is a good treatment option for intra-canalicular vestibular schwannomas when surgical excision is needed. BACKGROUND: Surgical outcomes of vestibular schwannoma have progressively improved with the advancement of microsurgical instruments. MFA is known to have better chances to preserve hearing, while it has limited access to the posterior fossa, limitation of tumor size, and higher risk of post-operative facial nerve weakness...
November 25, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27882946/er-stress-inhibitor-attenuates-hearing-loss-and-hair-cell-death-in-cdh23-erl-erl-mutant-mice
#11
Juan Hu, Bo Li, Luke Apisa, Heping Yu, Shami Entenman, Min Xu, Ruben Stepanyan, Bo-Jhih Guan, Ulrich Müller, Maria Hatzoglou, Qing Yin Zheng
Hearing loss is one of the most common sensory impairments in humans. Mouse mutant models helped us to better understand the mechanisms of hearing loss. Recently, we have discovered that the erlong (erl) mutation of the cadherin23 (Cdh23) gene leads to hearing loss due to hair cell apoptosis. In this study, we aimed to reveal the molecular pathways upstream to apoptosis in hair cells to exploit more effective therapeutics than an anti-apoptosis strategy. Our results suggest that endoplasmic reticulum (ER) stress is the earliest molecular event leading to the apoptosis of hair cells and hearing loss in erl mice...
November 24, 2016: Cell Death & Disease
https://www.readbyqxmd.com/read/27879225/efficacy-of-posterior-canal-wall-reconstruction-using-autologous-auricular-cartilage-and-bone-p%C3%A3-t%C3%A3-in-chronic-otitis-media-with-cholesteatoma
#12
Min Kwan Baek, Sung Ho Choi, Dong Young Kim, Chang Hyun Cho, Yong Woo Kim, Kwang Ha Moon, Ju Hyoung Lee
OBJECTIVE: This study was designed to investigate the long-term results using the technique of canal wall up mastoidectomy and reconstruction of the posterior canal wall using bone pâté and auricular cartilage in the treatment of chronic otitis media with cholesteatoma. MATERIALS AND METHODS: A retrospective review was performed on 42 patients who underwent canal wall up mastoidectomy and posterior canal wall reconstruction at a single institution between November 2005 and November 2012...
November 23, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27878601/reduction-of-permanent-hearing%C3%A2-loss-by-local-glucocorticoid-application-guinea-pigs-with-acute-acoustic-trauma
#13
M Müller, M Tisch, H Maier, H Löwenheim
BACKGROUND: High-intensity noise exposure from impulse and blast noise events often leads to acute hearing loss and may cause irreversible permanent hearing loss as a long-term consequence. Here, a treatment regime was developed to limit permanent damage based on a preclinical animal model of acute noise trauma. AIM: To develop clinical trials for the treatment of acute noise traumas using approved drugs. The otoprotective potential of glucocorticoids applied locally to the inner ear was examined...
November 23, 2016: HNO
https://www.readbyqxmd.com/read/27866146/hearing-preservation-after-penetrating-cochlear-injury
#14
George S Tarasidis, Richard H Wiggins, Richard K Gurgel
OBJECTIVES: To share results and recommendations for management of penetrating cochlear injury. METHODS: A patient underwent repair of a penetrating cochlear injury after a projectile led to a traumatic cochleostomy with a narrow miss of the facial nerve and intracranial carotid artery. RESULTS: Postoperatively, the patient's audiogram demonstrated a pure tone average of 47.5 dB for air conduction and 35 dB for bone conduction, worse in the high frequencies, with a Word Recognition Score of 76%...
November 19, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27852135/long-term-results-of-hearing-preservation-cochlear-implant-surgery-in-patients-with-residual-low-frequency-hearing
#15
Hideaki Moteki, Shin-Ya Nishio, Maiko Miyagawa, Keita Tsukada, Satoshi Iwasaki, Shin-Ichi Usami
CONCLUSION: Differences were found between patients with stable hearing and those with progressive hearing loss in the lower frequencies with respect to the rate of progression in the contralateral ear. It is suggested that the electric acoustic stimulation (EAS) can provide improvement in hearing ability over the long-term if residual hearing might be lost to some extent. OBJECTIVE: To evaluate the long-term threshold changes in the low frequency hearing of the implanted ear as compared with the non-implanted ear, and the hearing abilities with EAS along with the extent of residual hearing...
November 17, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27832010/response-to-comment-on-a-systematic-review-on-complications-of-tissue-preservation-surgical-techniques-in-percutaneous-bone-conduction-hearing-devices
#16
Emmy Verheij, Aren Bezdjian, Wilko Grolman, Henricus G X M Thomeer
No abstract text is available yet for this article.
November 9, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27832009/comment-on-a-systematic-review-on-complications-of-tissue-preservation-surgical-techniques-in-percutaneous-bone-conduction-hearing-devices
#17
Ivo J Kruyt, Christine A den Besten, Rik C Nelissen, Myrthe K S Hol
No abstract text is available yet for this article.
November 9, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27829464/minimally-invasive-ponto-surgery-compared-to-the-linear-incision-technique-without-soft-tissue-reduction-for-bone-conduction-hearing-implants-study-protocol-for-a-randomized-controlled-trial
#18
Tim G A Calon, Marc van Hoof, Herbert van den Berge, Arthur J G de Bruijn, Joost van Tongeren, Janny R Hof, Jan Wouter Brunings, Sofia Jonhede, Lucien J C Anteunis, Miranda Janssen, Manuela A Joore, Marcus Holmberg, Martin L Johansson, Robert J Stokroos
BACKGROUND: Over the last years, less invasive surgical techniques with soft tissue preservation for bone conduction hearing implants (BCHI) have been introduced such as the linear incision technique combined with a punch. Results using this technique seem favorable in terms of rate of peri-abutment dermatitis (PAD), esthetics, and preservation of skin sensibility. Recently, a new standardized surgical technique for BCHI placement, the Minimally Invasive Ponto Surgery (MIPS) technique has been developed by Oticon Medical AB (Askim, Sweden)...
November 9, 2016: Trials
https://www.readbyqxmd.com/read/27818997/the-role-of-the-transcription-factor-foxo3-in-hearing-maintenance-informed-speculation-on-a-new-player-in-the-cochlea
#19
REVIEW
Patricia M White
Molecular genetics has proven to be a powerful approach for understanding early-onset hearing loss. Recent work in late-onset hearing loss uses mouse genetics to identify molecular mechanisms that promote the maintenance of hearing. One such gene, Foxo3, is ontologically involved in preserving mitochondrial function. Significant evidence exists to support the idea that mitochondrial dysfunction is correlated with and can be causal for hearing loss. Foxo3 is also ontologically implicated in driving the circadian cycle, which has recently been shown to influence the molecular response to noise damage...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27816972/vestibular-schwannoma-resection-with-ipsilateral-simultaneous-cochlear-implantation-in-patients-with-normal-contralateral-hearing
#20
Mario Sanna, María Del Mar Medina, Aldin Macak, Gianluca Rossi, Valerio Sozzi, Sampath Chandra Prasad
OBJECTIVE: To report the hearing results of cochlear implantation simultaneous to vestibular schwannoma (VS) resection by means of a translabyrinthine approach in patients with normal contralateral hearing. METHODS: This was a prospective study including adults with sporadic VS. Tumors were resected by means of a modified translabyrinthine approach with preservation of the cochlear nerve. RESULTS: A total of 13 patients underwent cochlear implantation...
November 5, 2016: Audiology & Neuro-otology
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