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Hearing Preservation

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https://www.readbyqxmd.com/read/28304096/insertion-depth-impacts-speech-perception-and-hearing-preservation-for-lateral-wall-electrodes
#1
Brendan P O'Connell, Jacob B Hunter, David S Haynes, Jourdan T Holder, Matt M Dedmon, Jack H Noble, Benoit M Dawant, George B Wanna
OBJECTIVES: 1) Examine angular insertion depths (AID) and scalar location of Med-El (GmbH Innsbruck, Austria) electrodes; and 2) determine the relationship between AID and audiologic outcomes controlling for scalar position. STUDY DESIGN: Retrospective review. METHODS: Postlingually deafened adults undergoing cochlear implantation with Flex 24, Flex 28, and Standard electrode arrays (Med-El) were identified. Patients with preoperative and postoperative computed tomography scans were included so that electrode location and AID could be determined...
March 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28301392/combined-electric-and-acoustic-stimulation-with-hearing-preservation-effect-of-cochlear-implant-low-frequency-cutoff-on-speech-understanding-and-perceived-listening-difficulty
#2
René H Gifford, Timothy J Davis, Linsey W Sunderhaus, Christine Menapace, Barbara Buck, Jillian Crosson, Lori O'Neill, Anne Beiter, Phil Segel
OBJECTIVE: The primary objective of this study was to assess the effect of electric and acoustic overlap for speech understanding in typical listening conditions using semidiffuse noise. DESIGN: This study used a within-subjects, repeated measures design including 11 experienced adult implant recipients (13 ears) with functional residual hearing in the implanted and nonimplanted ear. The aided acoustic bandwidth was fixed and the low-frequency cutoff for the cochlear implant (CI) was varied systematically...
March 15, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28301390/pre-and-postoperative-binaural-unmasking-for-bimodal-cochlear-implant-listeners
#3
Benjamin M Sheffield, Gerald Schuchman, Joshua G W Bernstein
OBJECTIVES: Cochlear implants (CIs) are increasingly recommended to individuals with residual bilateral acoustic hearing. Although new hearing-preserving electrode designs and surgical approaches show great promise, CI recipients are still at risk to lose acoustic hearing in the implanted ear, which could prevent the ability to take advantage of binaural unmasking to aid speech recognition in noise. This study examined the tradeoff between the benefits of a CI for speech understanding in noise and the potential loss of binaural unmasking for CI recipients with some bilateral preoperative acoustic hearing...
March 15, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28298021/prophylactic-nimodipine-treatment-and-improvement-in-hearing-outcome-after-vestibular-schwannoma-surgery-a-combined-analysis-of-a-randomized-multicenter-phase-iii-trial-and-its-pilot-study
#4
Christian Scheller, Andreas Wienke, Marcos Tatagiba, Alireza Gharabaghi, Kristofer F Ramina, Oliver Ganslandt, Barbara Bischoff, Johannes Zenk, Tobias Engelhorn, Cordula Matthies, Thomas Westermaier, Gregor Antoniadis, Maria Teresa Pedro, Veit Rohde, Kajetan von Eckardstein, Thomas Kretschmer, Malte Kornhuber, Jörg Steighardt, Michael Richter, Fred G Barker, Christian Strauss
OBJECT In clinical routines, neuroprotective strategies in neurosurgical interventions are still missing. A pilot study (n = 30) and an analogously performed Phase III trial (n = 112) pointed to a beneficial effect of prophylactic nimodipine and hydroxyethyl starch (HES) in vestibular schwannoma (VS) surgery. Considering the small sample size, the data from both studies were pooled. METHODS The patients in both investigator-initiated studies were assigned to 2 groups. The treatment group (n = 70) received parenteral nimodipine (1-2 mg/hour) and HES (hematocrit 30%-35%) from the day before surgery until the 7th postoperative day...
February 24, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28291479/does-combat-hearing-preservation-equipment-affect-balance
#5
Art Ambrosio, Ali N Hoffer, Michael Hoffer
OBJECTIVES: (1) To investigate whether the occlusion effect and hearing attenuation produced by 3M Combat Arms Ear Plugs (CAEP) affects balance when compared to no hearing protection and (2) to investigate whether the occlusion effect and noise-canceling capabilities of the Nacre QuietPro system affects balance when compared to no hearing protection. METHODS: This prospective study collected pilot data for investigation of mechanisms of balance. 20 subjects with normal hearing and no vestibular dysfunction were tested with blackened goggles in three conditions-no hearing protection, CAEP, and with the Nacre QuietPro...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28288478/benign-temporomandibular-joint-lesions-presenting-as-masses-in-the-external-auditory-canal
#6
Ryan A Williams, Robert K Jackler, C Eduardo Corrales
OBJECTIVE: Describe benign lesions arising from the temporomandibular joint (TMJ) that presented as masses in the external auditory canal (EAC). STUDY DESIGN: Retrospective case series of two academic medical centers. PATIENTS: Six patients with lesions emanating from the TMJ that presented as EAC masses. Lesions included pigmented villonodular synovitis (PVNS), nodular fasciitis, foramen of Huschke herniation with salivary fistula, fibroepithelial polyp, superficial angiomyxoma, and giant cell tumor (GCT)...
April 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28264554/hearing-improvement-in-a-j-mice-via-the-mouse-nerve-growth-factor
#7
Lixiang Gao, Ruli Ge, Gang Xie, Dandan Yao, Ping Li, Oumei Wang, Xiufang Ma, Fengchan Han
Objectives: To investigate the otoprotective effects of mouse nerve growth factor (mNGF) in A/J mice. Methods: The mice at postnatal day 7 (P7) were randomly separated into a mNGF treated group (mNGF group) and a distilled water (for injection) treated group (control group). The mNGF dissolved in distilled water or distilled water alone was given to the mice once every other day from P7 by intramuscular injection in the hips. The otoprotective effects of mNGF in A/J mice were observed in a time course manner...
March 8, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28253641/sensorineural-hearing-loss-enhances-auditory-sensitivity-and-temporal-integration-for-amplitude-modulation
#8
Nicolas Wallaert, Brian C J Moore, Stephan D Ewert, Christian Lorenzi
Amplitude-modulation detection thresholds (AMDTs) were measured at 40 dB sensation level for listeners with mild-to-moderate sensorineural hearing loss (age: 50-64 yr) for a carrier frequency of 500 Hz and rates of 2 and 20 Hz. The number of modulation cycles, N, varied between two and nine. The data were compared with AMDTs measured for young and older normal-hearing listeners [Wallaert, Moore, and Lorenzi (2016). J. Acoust. Soc. Am. 139, 3088-3096]. As for normal-hearing listeners, AMDTs were lower for the 2-Hz than for the 20-Hz rate, and AMDTs decreased with increasing N...
February 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28238160/insertion-forces-and-intracochlear-trauma-in-temporal-bone-specimens-implanted-with-a-straight-atraumatic-electrode-array
#9
Marjan Mirsalehi, Thomas S Rau, Lenka Harbach, Silke Hügl, Saleh Mohebbi, Thomas Lenarz, Omid Majdani
The aim of the study was to evaluate insertion forces during manual insertion of a straight atraumatic electrode in human temporal bones, and post-implantation histologic evaluation of the samples to determine whether violation of intracochlear structures is related to insertion forces. In order to minimize intracochlear trauma and preserve residual hearing during cochlear implantation, knowledge of the insertion forces is necessary. Ten fresh frozen human temporal bones were prepared with canal wall down mastoidectomy...
February 25, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28219164/-a-combination-use-of-endoscope-and-microscope-in-cerebral-pontine-angle-surgery
#10
Z Y Wang, H Jia, J Yang, H Y Tan, H Wu
Objective: To evaluate the application of combination use of microscope and endoscope in cerebral pontine angle (CPA) surgery. Methods: A total of 72 patients undergone lateral skull base surgeries via endoscope under microscopic control from January 2006 to January 2015 was reviewed respectively. The patients including 35 males and 37 females were composed of 22 cases of vestibular swannnomas, 45 cases of cranial neuropathy and 5 cases of CPA chelesteatoma. Twenty cases of vestibular swannnomas, 15 cases of cranial neuropathy and 2 cases of CPA chelesteatoma undergone the surgery via retrosigmoid approach, while other cases undergone the surgery via retrolabyrinthine approach...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28207578/the-impact-of-a-cochlear-implant-electrode-array-on-the-middle-ear-transfer-function
#11
David Pazen, Andreas Anagiotos, Maike Nünning, Antoniu-Oreste Gostian, Magdalene Ortmann, Dirk Beutner
OBJECTIVES: As a treatment for partial deafness with residual hearing in the lower frequency range, the combined acoustic and electric stimulation of the cochlea has become widespread. Acoustic stimulation is provided by a hearing aid's airborne sound and the electric stimulation by a cochlear implant electrode array, which may be inserted through the round window or a cochleostomy. To take advantage of that concept, it is essential to preserve residual hearing after surgery. Therefore, the intracochlear electrode array should not compromise the middle ear vibration transmission...
February 15, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28193245/early-disease-progression-of-hurler-syndrome
#12
Bridget T Kiely, Jennifer L Kohler, Hannah Y Coletti, Michele D Poe, Maria L Escolar
BACKGROUND: Newborn screening for mucopolysaccharidosis type I (MPS I) shows promise to improve outcomes by facilitating early diagnosis and treatment. However, diagnostic tests for MPS I are of limited value in predicting whether a child will develop severe central nervous system disease associated with Hurler syndrome, or minimal or no central nervous system involvement associated with the attenuated phenotypes (Hurler-Scheie and Scheie syndromes). Given that the optimal treatment differs between Hurler syndrome and the attenuated MPS I phenotypes, the absence of a reliable prognostic biomarker complicates clinical decision making for infants diagnosed through newborn screening...
February 14, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28180036/low-dose-gamma-knife-radiosurgery-for-vestibular-schwannomas-tumor-control-and-cranial-nerve-function-preservation-after-11-gy
#13
Andrew J Schumacher, Rohan R Lall, Rishi R Lall, Allan Nanney Iii, Amit Ayer, Samir Sejpal, Benjamin P Liu, Maryanne Marymont, Plato Lee, Bernard R Bendok, John A Kalapurakal, James P Chandler
Objectives This study aims to report tumor control rates and cranial nerve function after low dose (11.0 Gy) Gamma knife radiosurgery (GKRS) in patients with vestibular schwannomas. Methods A retrospective chart review was performed on 30 consecutive patients with vestibular schwannomas treated from March 2004 to August 2010 with GKRS at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. The marginal dose for all patients was 11.0 Gy prescribed to the 50% isodose line. Median follow-up time was 42 months...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28167016/lateral-skull-base-surgery-in-a-pediatric-population-a-25-year-experience-in-a-referral-skull-base-center
#14
Golda Grinblat, Sampath Chandra Prasad, Andrea Fulcheri, Melissa Laus, Alessandra Russo, Mario Sanna
OBJECTIVE: To analyze the pathology and surgical outcomes of lateral skull base (LSB) procedures in a pediatric population. STUDY DESIGN: Retrospective case review in a referral skull base center. METHODS: Charts of pediatric patients who underwent defined LSB procedures from 1983 to 2015 for various pathologies were evaluated at our center. A systematic review of literature was performed and our results were compared with the literature. RESULTS: 63 patients presented with 65 diseased ears...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28165504/implementation-of-a-method-to-visualize-noise-induced-hearing-loss-in-mass-stranded-cetaceans
#15
Maria Morell, Andrew Brownlow, Barry McGovern, Stephen A Raverty, Robert E Shadwick, Michel André
Assessment of the impact of noise over-exposure in stranded cetaceans is challenging, as the lesions that lead to hearing loss occur at the cellular level and inner ear cells are very sensitive to autolysis. Distinguishing ante-mortem pathology from post-mortem change has been a major constraint in diagnosing potential impact. Here, we outline a methodology applicable to the detection of noise-induced hearing loss in stranded cetaceans. Inner ears from two mass strandings of long-finned pilot whales in Scotland were processed for scanning electron microscopy observation...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28159538/the-effect-of-systemic-lipoic-acid-on-hearing-preservation-after-cochlear-implantation-via-the-round-window-approach-a-guinea-pig-model
#16
Mun Young Chang, Tae Mok Gwon, Ho Sun Lee, Jun Ho Lee, Seung Ha Oh, Sung June Kim, Min-Hyun Park
The present study aimed to evaluate the effects of systemic lipoic acid on hearing preservation after cochlear implantation. Twelve Dunkin-Hartley guinea pigs were randomly divided into two groups: the control group and the lipoic acid group. Animals in the lipoic acid group received lipoic acid intraperitoneally for 4 weeks. A sterilised silicone electrode-dummy was inserted through the round window to a depth of approximately 5 mm. The hearing level was measured using auditory brainstem responses (ABRs) prior to electrode-dummy insertion, and at 4 days and 1, 2, 3 and 4 weeks after electrode-dummy insertion...
January 31, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28154277/mitochondrial-cardiomyopathy-with-a-unique-99m-tc-mibi-123-i-bmipp-mismatch-pattern
#17
Ryosuke Tashiro, Noriko Onoue, Hiroya Rikimaru, Kenichi Tsukita, Hiroshi Fujita, Nobuhiro Yamaguchi, Takeshi Ishizuka, Yasushi Suzuki, Hiroyoshi Suzuki, Tsuyoshi Shinozaki
A 42-year-old man was referred to our hospital due to chest pain, diabetes mellitus, and sensorineural hearing loss. Transthoracic echocardiography revealed diffuse left ventricular hypokinesis. He was diagnosed with mitochondrial disease and a c.A3243G mutation was identified in his mitochondrial DNA. This case of mitochondrial cardiomyopathy demonstrated a low uptake of (123)I-BMIPP, while the uptake of (99m)Tc-MIBI was preserved. In contrast, previous reports have noted the increased uptake of(123)I-BMIPP and the decreased uptake of (99m)Tc-MIBI...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28147573/low-frequency-fine-structure-cues-allow-for-the-online-use-of-lexical-stress-during-spoken-word-recognition-in-spectrally-degraded-speech
#18
Ying-Yee Kong, Alexandra Jesse
English listeners use suprasegmental cues to lexical stress during spoken-word recognition. Prosodic cues are, however, less salient in spectrally degraded speech, as provided by cochlear implants. The present study examined how spectral degradation with and without low-frequency fine-structure information affects normal-hearing listeners' ability to benefit from suprasegmental cues to lexical stress in online spoken-word recognition. To simulate electric hearing, an eight-channel vocoder spectrally degraded the stimuli while preserving temporal envelope information...
January 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28137246/functional-outcome-and-complications-after-the-microsurgical-removal-of-giant-vestibular-schwannomas-via-the-retrosigmoid-approach-a-retrospective-review-of-16-year-experience-in-a-single-hospital
#19
Xiang Huang, Jian Xu, Ming Xu, Mingyu Chen, Kaiyuan Ji, Junwei Ren, Ping Zhong
BACKGROUND: Intracranial vestibular schwannoma still remain to be difficulty for its unique microsurgical technique and preservation of neuro-function, as well as reducing common complications that may arise in surgery. METHODS: We consecutively enrolled 657 unilateral giant (>4 cm diameter) vestibular schwannoma patients treated in Huashan Hospital via the suboccipital retrosigmoid approach in the past 16 years. The extension of tumor removal, surgical mortality, facial nerve function, hearing, and the other main short and long-term complications were the studied parameters...
January 31, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28128697/gamma-knife-radiosurgery-for-treatment-of-growing-vestibular-schwannomas-in-patients-with-neurofibromatosis-type-2-a-matched-cohort-study-with-sporadic-vestibular-schwannomas
#20
Ivo J Kruyt, Jeroen B Verheul, Patrick E J Hanssens, Henricus P M Kunst
OBJECTIVE Neurofibromatosis Type 2 (NF2) is a tumor syndrome characterized by an autosomal dominant pattern of inheritance. The hallmark of NF2 is the development of bilateral vestibular schwannomas (VSs), generally by 30 years of age. One of the first-line treatment options for small to medium-large VSs is radiosurgery. Although radiosurgery shows excellent results in sporadic VS, its use in NF2-related VS is still a topic of dispute. The aim of this study was to evaluate long-term tumor control, hearing preservation rates, and factors influencing outcome of optimally dosed, contemporary Gamma Knife radiosurgery (GKRS) for growing VSs in patients with NF2 and compare the findings to data obtained in patients with sporadic VS also treated by means of GKRS...
January 27, 2017: Journal of Neurosurgery
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