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https://www.readbyqxmd.com/read/28822730/an-unusual-cause-of-upper-gastrointestinal-bleeding
#1
I-Chang Lin, Ching-Tai Lee, Yao-Chun Hsu, Chao-Ming Tseng
No abstract text is available yet for this article.
July 29, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28822355/baseline-assessment-of-25-hydroxyvitamin-d-assay-performance-a-vitamin-d-standardization-program-vdsp-interlaboratory-comparison-study
#2
Stephen Wise, Karen Phinney, Susan Tai, Johanna Camara, Gary Myers, Ramon Durazo-Arvizu, Lu Tian, Andrew Hoofnagle, Lorin Bachmann, Ian Young, Juanita Pettit, Grahame Caldwell, Andrew Liu, Stephen Brooks, Kurtis Sarafin, Michael Thamm, Gert Mensink, Markus Busch, Martina Rabenberg, Kevin Cashman, Mairead Kiely, Michael Kinsella, Karen Galvin, Joy Zhang, Kyungwon Oh, Sun-Wha Lee, Chae Jung, Lorna Cox, Gail Goldberg, Kate Guberg, Ann Prentice, Graham Carter, Julia Jones, Patsy Brannon, Robyn Lucas, Peter Crump, Etienne Cavalier, Joyce Merkel, Joseph Betz, Christopher Sempos
The Vitamin D Standardization Program (VDSP) coordinated an interlaboratory study to assess the comparability of measurements of total 25-hydroxyvitamin D [25(OH)D] in human serum, which is the primary marker of vitamin D status. A set of 50 individual donor samples were analyzed by 15 different laboratories representing national nutrition surveys, assay manufacturers, and clinical and/or research laboratories to provide results for total 25(OH)D using both immunoassays (IAs) and LC tandem MS (MS/MS). The results were evaluated relative to bias compared with the target values assigned based on a combination of measurements at Ghent University (Belgium) and the U...
August 19, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28822063/mind-body-therapies-in-cancer-what-is-the-latest-evidence
#3
REVIEW
Linda E Carlson, Erin Zelinski, Kirsti Toivonen, Michelle Flynn, Maryam Qureshi, Katherine-Ann Piedalue, Rachel Grant
PURPOSE OF REVIEW: Many people living with cancer use complementary therapies, and some of the most popular are mind-body therapies (MBTs), including relaxation and imagery, hypnosis, yoga, meditation, tai chi and qigong, and art therapies. The efficacy of these modalities was reviewed by assessing recent findings in the context of cancer care. RECENT FINDINGS: These therapies show efficacy in treating common cancer-related side effects, including nausea and vomiting, pain, fatigue, anxiety, depressive symptoms and improving overall quality of life...
August 18, 2017: Current Oncology Reports
https://www.readbyqxmd.com/read/28821665/molecular-and-functional-properties-of-regional-astrocytes-in-the-adult-brain
#4
Lydie Morel, Ming Sum R Chiang, Haruki Higashimori, Temitope Shoneye, Lakshmanan K Iyer, Julia Yelick, Albert Tai, Yongjie Yang
The molecular signature and functional properties of astroglial subtypes in the adult central nervous system (CNS) remain largely undefined. By employing translational ribosome affinity purification (TRAP) followed by RNA-seq, we profiled astroglial ribosome-associated (presumably translating) mRNAs in major cortical and subcortical brain regions (cortex, hippocampus, caudate putamen, nucleus accumbens, thalamus, and hypothalamus) of BAC aldh1l1-TRAP mice (both sexes). We found that the expression of astroglial translating mRNAs closely follows the dorsoventral axis especially from cortex/hippocampus to thalamus/hypothalamus posteriorly...
August 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821509/does-tai-chi-improve-psychological-well-being-and-quality-of-life-in-patients-with-cardiovascular-disease-and-or-cardiovascular-risk-factors-a-systematic-review-protocol
#5
Guoyan Yang, Wenyuan Li, Huijuan Cao, Nerida Klupp, Jianping Liu, Alan Bensoussan, Hosen Kiat, Dennis Chang
INTRODUCTION: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide. Psychological risk factors such as stress, anxiety and depression are known to play a significant and independent role in the development and progression of CVD and its risk factors. Tai Chi has been reported to be potentially effective for health and well-being. It is of value to assess the effectiveness and safety of Tai Chi on psychological well-being and quality of life in people with CVD and/or cardiovascular risk factors...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821088/microparticles-prepared-with-50-190kda-chitosan-as-promising-non-toxic-carriers-for-pulmonary-delivery-of-isoniazid
#6
Paula M Oliveira, Breno N Matos, Priscilla A T Pereira, Taís Gratieri, Lucia H Faccioli, Marcílio S S Cunha-Filho, Guilherme M Gelfuso
Chitosan biocompatibility and mucoadhesiveness make it an ideal polymer for antituberculotic drugs microcapsulation for pulmonary delivery. Yet, previous study indicated toxicity problems to J-774.1-cells treated with some medium molecular weight (190-310kDa) chitosan microparticles. As polymer molecular weight is a crucial factor to be considered, this paper describes the preparation and characterization of chitosan (50-190kDa) microparticles containing isoniazid (INH). Cytotoxicity assays were also performed on murine peritoneal (J-774...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820710/accuracy-of-a-rapid-diagnostic-test-cypress-chagas-quick-test-%C3%A2-for-the-diagnosis-of-chronic-chagas-disease-in-a-nonendemic-area-a-retrospective-longitudinal-study
#7
Andrea Angheben, Silvia Staffolani, Mariella Anselmi, Stefano Tais, Monica Degani, Federico Gobbi, Dora Buonfrate, Maria Gobbo, Zeno Bisoffi
We analyzed the accuracy of Chagas Quick Test(®), a rapid diagnostic test, for the diagnosis of chronic Chagas disease through a retrospective study on a cohort of 669 patients consecutively examined at a single reference center in Italy, during a 7-year period. We observed high concordance with serological reference standard but low accuracy for screening purposes (sensitivity/specificity: 82.8%/98.7%) at least in our nonendemic context.
August 14, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28820652/decreasing-stroke-code-to-ct-time-in-patients-presenting-with-stroke-symptoms
#8
Aleksandrs Kalnins, L Jake Mickelsen, Daisha Marsh, Christoph Zorich, Stephanie Casal, Waimei Amy Tai, Nirali Vora, Gennette Olalia, Max Wintermark, David B Larson
Guided quality improvement (QI) programs present an effective means to streamline stroke code to computed tomography (CT) times in a comprehensive stroke center. Applying QI methods and a multidisciplinary team approach may decrease the stroke code to CT time in non-prenotified emergency department (ED) patients presenting with symptoms of stroke. The aim of this project was to decrease this time for non-prenotified stroke code patients from a baseline mean of 20 minutes to one less than 15 minutes during an 18-week period by applying QI methods in the context of a structured QI program...
August 18, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28820636/clinical-effects-of-cpg-based-treatment-on-the-efficacy-of-hepatocellular-carcinoma-by-skewing-polarization-toward-m1-macrophage-from-m2
#9
Qing Zhang, Ru-Fei Yuan, Xiao-Huan Li, Tai-An Xu, Yan-Ni Zhang, Xiao-Lin Yuan, Yi-Fen Cui, Wan Shen, Qing-Lin Guan, Xiu-Yan Sun
OBJECTIVE: This study aims to explore the clinical efficacy of CpG-based therapy for treating hepatocellular carcinoma (HCC) by skewing polarization toward M1 macrophage from M2. METHODS: Pulmonary metastasis rate, overall survival time, and remission rate of 10 patients with HCC treated with transcatheter arterial chemoembolization (TACE) combined with CpG therapy and 10 age-, gender-, and TNM0-matched patients treated with TACE (control group) were compared. RESULTS: No pulmonary metastasis rate was 70% in the combined treatment group and 40% in the control group, respectively; and the differences between the two groups were statistically significant (p < 0...
August 2017: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/28820379/conveyance-contact-investigation-for-imported-middle-east-respiratory-syndrome-cases-united-states-may-2014
#10
Susan A Lippold, Tina Objio, Laura Vonnahme, Faith Washburn, Nicole J Cohen, Tai-Ho Chen, Paul J Edelson, Reena Gulati, Christa Hale, Jennifer Harcourt, Lia Haynes, Amy Jewett, Robynne Jungerman, Katrin S Kohl, Congrong Miao, Nicolette Pesik, Joanna J Regan, Efrosini Roland, Chris Schembri, Eileen Schneider, Azaibi Tamin, Kathleen Tatti, Francisco Alvarado-Ramy
In 2014, the Centers for Disease Control and Prevention conducted conveyance contact investigations for 2 Middle East respiratory syndrome cases imported into the United States, comprising all passengers and crew on 4 international and domestic flights and 1 bus. Of 655 contacts, 78% were interviewed; 33% had serologic testing. No secondary cases were identified.
September 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28820337/paper-title-circular-rnas-isolation-characterisation-and-their-potential-role-in-diseases
#11
Lumei Liu, Jian Wang, Ramin Khanabdali, Bill Kalionis, Xiantao Tai, Shijin Xia
Circular RNA (circRNA) generated by alternative splicing represents a special class of non-coding RNA molecule. CircRNAs are abundant in the eukaryotic cell cytoplasm and have a characteristic organization, timing of action and disease specificity. In contrast to linear RNA, circRNAs are resistant to RNA exonuclease. Consequently, circRNA escapes normal RNA turnover and this improves circRNA stability. CircRNAs can be degraded by microRNA (miRNA) and this results in linearization of the circRNA, which can then act as competitor to endogenous RNA...
August 18, 2017: RNA Biology
https://www.readbyqxmd.com/read/28819842/separable-bilayer-microfiltration-device-for-label-free-enrichment-of-viable-circulating-tumor-cells
#12
Sijie Hao, Merisa Nisic, Hongzhang He, Yu-Chong Tai, Si-Yang Zheng
Analysis of rare circulating tumor cells enriched from metastatic cancer patients yields critical information on disease progression, therapy response, and the mechanism of cancer metastasis. Here we describe in detail a label-free enrichment process of circulating tumor cells based on its unique physical properties (size and deformability). Viable circulating tumor cells can be successfully enriched and analyzed, or easily released for further characterization due to the novel separable two-layer design.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28818559/-to-boldly-go-where-no-one-has-gone-before
#13
Keith W Kelley
Americans are suffering from a culture of taking pills. Six out of ten Americans utilize at least one prescription drug, and more than one in ten use five or more prescription medicines. Although this torrent of taking pills is already high, drug use in the USA has not yet crested. Prescription drugs have specific targets, but often they adversely affect other tissues and organs. In keeping with the mission of the recently named National Center for Complementary and Integrative Health (NCCIH), Brain, Behavior, and Immunity searches for the underlying cause and potential efficacy of both drug and non-drug interventions...
August 14, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28817703/quality-of-life-of-inguinal-hernia-patients-in-taiwan-the-application-of-the-hernia-specific-quality-of-life-assessment-instrument
#14
Chi-Cheng Huang, Feng-Chuan Tai, Tzung-Hsin Chou, Heng-Hui Lien, Jaan-Yeh Jeng, Thien-Fiew Ho, Ching-Shui Huang
BACKGROUND: With the development of prosthetic mesh and tension free techniques, the recurrence rate following inguinal hernia repair has been reduced, and hernia outcomes research should focus on post-operative quality of life and potential complications. STUDY DESIGN: A novel hernia quality of life assessment instrument, HERQL, was developed. The HERQL questionnaire comprises a 4-item summative pain score measuring pain and discomfort resulting from various strenuous activities...
2017: PloS One
https://www.readbyqxmd.com/read/28817486/overcoming-clopidogrel-resistance-three-promising-novel-antiplatelet-drugs-developed-in-china
#15
Hong-Guang Xie, Yu-Meng Jia, Ting Tai, Jin-Zi Ji
Clopidogrel is one of the most frequently prescribed drugs worldwide; however, the presence of clopidogrel resistance and high susceptibility to genetic variations and drug interactions are facilitating the development of other antiplatelet drugs. To overcome clopidogrel resistance, several promising clopidogrel analogues have been developed in China, such as vicagrel (and its deuterated analogues), PLD-301, and W1. These novel chemical analogues are all characterized by much faster and more efficient bioconversion to clopidogrel thiolactone (or 2-oxo-clopidogrel, the precursor of clopidogrel active metabolite) in the intestine than clopidogrel through bypassing the first-step P450-mediated oxidation of clopidogrel in the liver...
August 4, 2017: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/28817102/anticancer-activity-of-ramalin-a-secondary-metabolite-from-the-antarctic-lichen-ramalina-terebrata-against-colorectal-cancer-cells
#16
Sung-Suk Suh, Tai Kyoung Kim, Jung Eun Kim, Ju-Mi Hong, Trang Thu Thi Nguyen, Se Jong Han, Ui Joung Youn, Joung Han Yim, Il-Chan Kim
Colorectal cancer is a leading cause of death worldwide and occurs through the highly complex coordination of multiple cellular pathways, resulting in carcinogenesis. Recent studies have increasingly revealed that constituents of lichen extracts exhibit potent pharmaceutical activities, including anticancer activity against various cancer cells, making them promising candidates for new anticancer therapeutic drugs. The main objective of this study was to evaluate the anticancer capacities of ramalin, a secondary metabolite from the Antarctic lichen Ramalina terebrata, in the human colorectal cancer cell line HCT116...
August 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28815249/-effect-of-hemostatic-agent-on-bonding-strength-of-deciduous-tooth-dentin
#17
Qiu-Hua Pan, Da-Wei Huang, Qing-Tai Wang
PUPPOSE: To investigate the effect of hemostatic agent on bonding strength of deciduous tooth dentin. METHODS: Forty deciduous molars were used to make dentin grinding model and randomly divided into observation group and control group, 20 teeth in each group. Teeth in the observation group were covered with hemostatic agent for 30s, and then washed, followed by processing; while teeth in the control group were subjected to bonding directly. Micro tensile bond strength and micro leakage were measured and compared in the two groups...
April 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/28814034/automated-assessment-of-symptom-severity-changes-during-deep-brain-stimulation-dbs-therapy-for-parkinson-s-disease
#18
Paolo Angeles, Yen Tai, Nicola Pavese, Samuel Wilson, Ravi Vaidyanathan
Deep brain stimulation (DBS) is currently being used as a treatment for symptoms of Parkinson's disease (PD). Tracking symptom severity progression and deciding the optimal stimulation parameters for people with PD is extremely difficult. This study presents a sensor system that can quantify the three cardinal motor symptoms of PD - rigidity, bradykinesia and tremor. The first phase of this study assesses whether data recorded from the system during physical examinations can be used to correlate to clinician's severity score using supervised machine learning (ML) models...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812352/ca-%C3%AE-sialon-eu-phosphors-oxidation-states-energy-transfer-and-emission-enhancement-by-incorporation-aimed-surface-engineering
#19
Xiangyang Chen, Lin Gan, Zhi-Jun Zhang, Ping Lu, Xionghui Zeng, Linlin Zhang, Heliang Yao, FangFang Xu, Jing-Tai Zhao
Ca-α-SiAlON: Eu is one of the most promising phosphors exhibiting potential applications in high power LEDs owing to its excellent thermal stability and relative high luminescence efficiency comparable to YAG: Ce commercial phosphors. The oxidation states of Eu ions in Ca-α-SiAlON: Eu are still questionable and furthermore it yet exhibits lower luminescence intensity than commercial yellow phosphors. Therefore, in the present work, the valances of Eu ions in Ca-α-SiAlON have been examined which observed a mixture of divalence and trivalence...
August 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28811955/the-effects-of-group-based-versus-individual-based-tai-chi-training-on-nonmotor-symptoms-in-patients-with-mild-to-moderate-parkinson-s-disease-a-randomized-controlled-pilot-trial
#20
Jing Hui Yang, Ya Qun Wang, Sai Qing Ye, You Gen Cheng, Yu Chen, Xiao Zhen Feng
OBJECTIVE: To compare the effects of group-based and individual-based Tai Chi training on nonmotor symptoms in patients with mild to moderate Parkinson's disease. DESIGN: Randomized controlled pilot study. METHODS: 36 community-dwelling patients with Parkinson's disease (PD) were randomly assigned to either group-based training group (n = 19) or individual-based group (n = 17). Both groups received same content of Tai Chi training 3 times a week for 13 weeks...
2017: Parkinson's Disease
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