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Heart variability

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https://www.readbyqxmd.com/read/28727839/cardiac-autonomic-modulation-induced-by-doxorubicin-in-a-rodent-model-of-colorectal-cancer-and-the-influence-of-fullerenol-pretreatment
#1
Nejka Potočnik, Martina Perše, Anton Cerar, Rade Injac, Žarko Finderle
The very effective anticancer drug doxorubicin (DOX) is known to have cardiotoxic side effects, which could be accompanied by autonomic modulation. Autonomic disbalance might even be an initiating mechanism underlying DOX-induced cardiotoxicity and can be studied noninvasively by the analysis of heart rate variability (HRV). A number of strategies have been assessed to predict chemotherapy-induced cardiac dysfunction while HRV, a potential detecting tool, has not yet been tested. Thus, we aimed to determine the effect of DOX treatment on HRV in a rat model of colorectal cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28727739/survival-analysis-of-heart-failure-patients-a-case-study
#2
Tanvir Ahmad, Assia Munir, Sajjad Haider Bhatti, Muhammad Aftab, Muhammad Ali Raza
This study was focused on survival analysis of heart failure patients who were admitted to Institute of Cardiology and Allied hospital Faisalabad-Pakistan during April-December (2015). All the patients were aged 40 years or above, having left ventricular systolic dysfunction, belonging to NYHA class III and IV. Cox regression was used to model mortality considering age, ejection fraction, serum creatinine, serum sodium, anemia, platelets, creatinine phosphokinase, blood pressure, gender, diabetes and smoking status as potentially contributing for mortality...
2017: PloS One
https://www.readbyqxmd.com/read/28727660/alcohol-use-disorder-moderates-the-effect-of-age-on-heart-rate-variability-in-veterans-with-posttraumatic-stress-disorder
#3
John M Ray, Jeffrey M Pyne, Richard N Gevirtz
Research on heart rate variability (HRV) in posttraumatic stress disorder (PTSD) and comorbid alcohol use disorder (AUD) is limited despite its use as a biomarker of both disorders. This study examined whether AUD comorbidity contributes an additive effect on HRV for veterans with PTSD. HRV was assessed in 70 male Operation Enduring Freedom/Operation Iraqi Freedom veterans with PTSD, including 32 with co-occurring AUD. Mean HRV values for both groups were below the mean for healthy adults, but additive effects of PTSD and AUD on HRV were not observed...
July 19, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28727025/effect-of-handling-intensity-at-the-time-of-transport-for-slaughter-on-physiological-response-and-carcass-characteristics-in-beef-cattle-fed-ractopamine-hydrochloride
#4
J A Hagenmaier, C D Reinhardt, S J Bartle, J N Henningson, M J Ritter, M S Calvo-Lorenzo, G J Vogel, C A Guthrie, M G Siemens, D U Thomson
The effects of handling intensity on the physiological response and carcass characteristics of feedlot cattle fed ractopamine hydrochloride were evaluated at the time of transport to slaughter. Eighty steers (BW = 668 ± 36 kg) representing 10 lots of similar breed, frame size, and degree of finish were blocked by lot, stratified by weight, and randomly assigned to 1 of 2 handling intensities (HI) over a 1,600 m dirt alley course: 1) low-stress handling (LSH) or 2) high-stress handling (HSH). For the LSH treatment, 4 penmates were kept at a walk with the use of a lead rider...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726973/heart-rate-variability-biofeedback-stress-relief-program-for-depression-a-replicated-single-subject-design
#5
Bregje M A Hartogs, Agna Bartels-Velthuis, Karen Van der Ploeg, Elske H Bos
BACKGROUND: Depressive disorders often have a chronic course and the efficacy of evidence-based treatments may be overestimated. OBJECTIVE: To examine the effectiveness of the Heart Rate Variability Stress Reduction Program (SRP) as a supplement to standard treatment in patients with depressive disorders. METHODS: The SRP was individually administered in eight weekly sessions. Seven participants completed the full protocol and were enrolled in a single-subject ABA multiple baseline experimental design...
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726661/-heart-rate-variability-in-children-with-false-chords-in-the-left-cardiac-ventricular
#6
A Kuleshov
We examined 64 children with false tendons in the left cardiac ventricular. The research included evaluation of time and frequency domain parameters of the heart rhythm with cardiointervalography. The parameter changes were noted. Thus, sympathetic vegetative system (VS) part prevalence was present in boys and characterized by decreasing of SDNN when compared with control data (85,4±5,8 и 158,2 ±25,6, р<0,05). rMSSD and PNN50%, which are responsible for parasympathetic VS part have the tendency to increasing in girls...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28726651/factors-associated-with-post-stroke-fatigue-within-the-first-3-month-after-stroke
#7
I Delva, N Lytvynenko, M Delva
Aim - identify socio-demographic, personal and psychological factors associated with certain post-stroke fatigue (PSF) domains within first 3 months after stroke. There were examined patients consequently in definite time points after ischemic or hemorrhagic strokes: at hospital stay (234 patients), in 1 month (203 patients) and in 3 months (176 patients). Global PSF and certain PSF domains were measured by multidimensional fatigue inventory-20 (MFI-20) scale. In multivariate logistic regression analysis the majority of variables (gender, marital status, education level, smoking status, level of alcohol consumption, apathetic impairments, arterial hypertension, atrial fibrillation, ischemic heart disease, diabetes mellitus, body mass index, waist circumference) were not significantly associated with any PSF domain risk at any time point after stroke...
June 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28725953/prognostic-significance-of-low-systolic-blood-pressure-at-discharge-in-patients-with-heart-failure-and-preserved-ejection-fraction
#8
Shijun Li, Xiaoying Li
INTRODUCTION: Systolic blood pressure (SBP) is emerging as a predictor of outcome in chronic heart failure and low SBP has been shown to be related to higher mortality. AIM: To investigate the relationship between low SBP and long-term outcome in patients with heart failure with preserved ejection fraction (HFpEF). METHODS: We use prospectively collected data and recruited 297 patients with chronic HFpEF to investigate the relationship between low SBP at discharge and long-term outcome...
July 19, 2017: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/28725326/comparison-of-clopidogrel-with-prasugrel-and-ticagrelor-in-patients-with-acute-coronary-syndrome-clinical-outcomes-from-the-national-cardiovascular-database-action-registry
#9
Mohamed Khayata, Joseph N Gabra, M Farhan Nasser, George I Litman, Shyam Bhakta, Rupesh Raina
BACKGROUND: We aimed to compare the clinical outcomes of clopidogrel, prasugrel, and ticagrelor in clinical practice using the National Cardiovascular Database ACTION Registry(®). Treatment guidelines for patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention recommend dual antiplatelet therapy (DAPT) for 12 months. Few clinical trials have compared the safety and efficacy of clopidogrel with that of newer antiplatelet therapies. METHODS: A retrospective study of patients hospitalized for ACS at Cleveland Clinic Akron General was conducted...
June 2017: Cardiology Research
https://www.readbyqxmd.com/read/28725206/physiological-signal-analysis-for-evaluating-flow-during-playing-of-computer-games-of-varying-difficulty
#10
Yu Tian, Yulong Bian, Piguo Han, Peng Wang, Fengqiang Gao, Yingmin Chen
Flow is the experience of effortless attention, reduced self-consciousness, and a deep sense of control that typically occurs during the optimal performance of challenging tasks. On the basis of the person-artifact-task model, we selected computer games (tasks) with varying levels of difficulty (difficult, medium, and easy) and shyness (personality) as flow precursors to study the physiological activity of users in a flow state. Cardiac and respiratory activity and mean changes in skin conductance (SC) were measured continuously while the participants (n = 40) played the games...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28725199/heart-performance-determination-by-visualization-in-larval-fishes-influence-of-alternative-models-for-heart-shape-and-volume
#11
Prescilla Perrichon, Martin Grosell, Warren W Burggren
Understanding cardiac function in developing larval fishes is crucial for assessing their physiological condition and overall health. Cardiac output measurements in transparent fish larvae and other vertebrates have long been made by analyzing videos of the beating heart, and modeling this structure using a conventional simple prolate spheroid shape model. However, the larval fish heart changes shape during early development and subsequent maturation, but no consideration has been made of the effect of different heart geometries on cardiac output estimation...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28724799/galantamine-alleviates-inflammation-and-insulin-resistance-in-patients-with-metabolic-syndrome-in-a-randomized-trial
#12
Fernanda M Consolim-Colombo, Carine T Sangaleti, Fernando O Costa, Tercio L Morais, Heno F Lopes, Josiane M Motta, Maria C Irigoyen, Luiz A Bortoloto, Carlos Eduardo Rochitte, Yael Tobi Harris, Sanjaya K Satapathy, Peder S Olofsson, Meredith Akerman, Sangeeta S Chavan, Meggan MacKay, Douglas P Barnaby, Martin L Lesser, Jesse Roth, Kevin J Tracey, Valentin A Pavlov
BACKGROUND: Metabolic syndrome (MetS) is an obesity-driven condition of pandemic proportions that increases the risk of type 2 diabetes and cardiovascular disease. Pathophysiological mechanisms are poorly understood, though inflammation has been implicated in MetS pathogenesis. The aim of this study was to assess the effects of galantamine, a centrally acting acetylcholinesterase inhibitor with antiinflammatory properties, on markers of inflammation implicated in insulin resistance and cardiovascular risk, and other metabolic and cardiovascular indices in subjects with MetS...
July 20, 2017: JCI Insight
https://www.readbyqxmd.com/read/28724511/apps-for-health-related-education-in-pharmacy-practice-needs-assessment-survey-among-patients-within-a-large-metropolitan-area
#13
Sean M Mirk, Nicole Marie Wegrzyn
BACKGROUND: Patient education resources are crucial to the effectiveness of prescribed pharmacotherapy. However, user interest and patient preference for these materials is lacking. Regardless of the field, nearly every article on designing mHealth apps references the lack of end-user involvement as a key flaw to sustainable design. The traditional paper-based methods of patient education are difficult to tailor to a patient's specific needs and learning styles, but a customizable app might be beneficial...
July 19, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28724493/oral-transmucosal-detomidine-gel-in-new-zealand-white-rabbits-oryctolagus-cuniculus
#14
Morika D Williams, C Tyler Long, Jessica R Durrant, Gabriel P McKeon, Heather R Shive, Emily H Griffith, Kristen M Messenger, Richard E Fish
Handling and restraining rabbits for routine procedures may be impossible without prior sedation, result in unnecessary stress or injury to the rabbit or handler, and increase experimental variability. Parenteral administration of sedatives can cause stress also, as well as localized pain and tissue damage, especially in fractious animals. Detomidine hydrochloride, an α2-adrenergic receptor agonist, is commercially available in an oral transmucosal (OTM) gel formulation that is FDA-approved for sedation and restraint in horses...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28724487/effect-of-wearing-a-telemetry-jacket-on-behavioral-and-physiologic-parameters-of-dogs-in-the-open-field-test
#15
Richard E Fish, Melanie L Foster, Margaret E Gruen, Barbara L Sherman, Davidc C Dorman
Safety pharmacology studies in dogs often integrate behavioral assessments made using video recording with physiologic measurements collected by telemetry. However, whether merely wearing the telemetry vest affects canine behavior and other parameters has not been evaluated. This pilot study assessed the effect of a telemetry vest on behavioral and physiologic responses to an environmental stressor, the sounds of a thunderstorm, in Labrador retrievers. Dogs were assigned to one of 2 experimental groups (Vest and No-Vest, n = 8 dogs per group) by using a matched pairs design, with a previously determined, sound-associated anxiety score as the blocking variable...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28724484/echocardiographic-parameters-of-clinically-normal-geriatric-rhesus-macaques-macacamulatta
#16
Yu Ueda, Catherine T Gunther-Harrington, Christina L Cruzen, Jeffrey A Roberts, Joshua A Stern
The goal of this study was to generate reference intervals for echocardiographic variables in a population of clinically normal geriatric rhesus macaques (Macaca mulatta). To do this, we studied 51 animals (age, 18-29 y; weight, 5.24-17.04 kg). The normal values for cardiac indices, including geometry and systolic and diastolic function, were determined by 2D, M-mode, spectral Doppler, and tissue Doppler echocardiography under ketamine hydrochloride sedation. Statistical correlations between the echocardiographic parameters and age, body weight, sex, and heart rate were investigated...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28723813/effect-of-resistance-training-on-blood-pressure-and-autonomic-responses-in-treated-hypertensives
#17
Gabriela Alves Trevizani, Mariana Balbi Seixas, Paulo Roberto Benchimol-Barbosa, Jeferson Macedo Vianna, Lilian Pinto da Silva, Jurandir Nadal
This study evaluated the effect of resistance training (RT) on heart rate variability (HRV) and on blood pressure (BP) responses to acute and short-term exposure in treated hypertensive subjects. Twenty one men participated in the study, eight hypertensive under drug treatment regimen and achieving adequate blood pressure control prior to inclusion (HT) and thirteen normotensive (NT). The RT protocol consisted of 12 sessions with 8 exercises (leg extension, leg press, leg curl, bench press, seated row, triceps push-down, seated calf flexion and seated arm curl) performed for 2 sets of 15-20 repetitions with 50% of one repetition-maximum (1RM) with 2-minute rest intervals in between sets, 3x/week...
July 17, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28723347/heart-rate-variability-is-enhanced-by-long-lasting-pleasant-touch-at-ct-optimized-velocity
#18
Chantal Triscoli, Ilona Croy, Susann Steudte-Schmiedgen, Håkan Olausson, Uta Sailer
INTRODUCTION: The present study explores whether long-lasting pleasant touch has positive effects on the stress response, reward sensitivity, mood, and interoceptive awareness. METHODS: 40 participants received either 35minutes of brush stroking targeting C-tactile fibres (CT) or vibration on the forearm, and rated pleasantness and intensity. Prior and after, stress response (cortisol and heart rate variability), reward sensitivity, mood and interoceptive awareness were measured...
July 16, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28722077/invasive-haemodynamic-evaluation-of-the-pulmonary-circulation-in-pulmonary-hypertension
#19
Alberto Pagnamenta, Andrea Azzola, Maurice Beghetti, Frédéric Lador, On Behalf Of The Swiss Society Of Pulmonary Hypertension
The term pulmonary hypertension refers to a serious condition characterised by high pulmonary vascular pressure, mainly as a consequence of various cardiac and respiratory diseases. Current clinical classification of pulmonary hypertension considers five distinct groups. Transthoracic echocardiography represents the first and most important noninvasive screening tool for estimating the probability of pulmonary hypertension. The diagnostic approach to pulmonary hypertension is supported by a proposed algorithm, which identifies the underlying cause...
July 19, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28721895/late-cardiac-toxicity-after-mediastinal-radiation-therapy-for-hodgkin-lymphoma-contributions-of-coronary-artery-and-whole-heart-dose-volume-variables-to-risk-prediction
#20
Ezra Hahn, Haiyan Jiang, Angela Ng, Shaheena Bashir, Sameera Ahmed, Richard Tsang, Alexander Sun, Mary Gospodarowicz, David Hodgson
PURPOSE: Mediastinal radiation therapy (RT) for Hodgkin lymphoma (HL) is associated with late cardiotoxicity, but there are limited data to indicate which dosimetric parameters are most valuable for predicting this risk. This study investigated which whole heart dosimetric measurements provide the most information regarding late cardiotoxicity, and whether coronary artery dosimetry was more predictive of this outcome than whole heart dosimetry. METHODS AND MATERIALS: A random sample of 125 HL patients treated with mediastinal RT was selected, and 3-dimensional cardiac dose-volume data were generated from historical plans using validated methods...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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