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Hematology , internal medicine

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https://www.readbyqxmd.com/read/27854183/prognostic-factors-in-the-survival-of-patients-with-blood-disorders-recovering-from-septic-shock
#1
Anna Waszczuk-Gajda, Wieslaw Wiktor Jedrzejczak
BACKGROUND: Septic shock is one of the major direct causes of death in patients in hematology departments. OBJECTIVES: The knowledge about clinical outcomes and factors associated with negative outcome in these patients can be important and useful for physicians to identify the patients who are most likely to benefit from ICU therapy. METHODS: We retrospectively analyzed records of 214 episodes of septic shock in patients with different blood diseases hospitalized between 1998 and 2011 in the Department of Hematology, Oncology and Internal Medicine, the Medical University of Warsaw, Poland...
November 17, 2016: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/27808467/measuring-pediatric-hematology-oncology-fellows-skills-in-humanism-and-professionalism-a-novel-assessment-instrument
#2
Jennifer C Kesselheim, Anurag K Agrawal, Nita Bhatia, Angel Cronin, Rima Jubran, Paul Kent, Leslie Kersun, Amulya Nageswara Rao, Melissa Rose, Stephanie Savelli, Mukta Sharma, Evan Shereck, Clare J Twist, Michael Wang
BACKGROUND: Educators in pediatric hematology-oncology lack rigorously developed instruments to assess fellows' skills in humanism and professionalism. PROCEDURE: We developed a novel 15-item self-assessment instrument to address this gap in fellowship training. Fellows (N = 122) were asked to assess their skills in five domains: balancing competing demands of fellowship, caring for the dying patient, confronting depression and burnout, responding to challenging relationships with patients, and practicing humanistic medicine...
November 3, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27790959/igg4-related-syndrome-another-multiorgan-disease-in-the-interest-field-of-internal-medicine
#3
Antonino Tuttolomondo, Irene Simonetta, Domenico Di Raimondo, Tiziana Di Chiara, Roberta Conigliaro, Francesca Corpora, Valerio Vassallo, Antonio Pinto
BACKGROUND: IgG4-related disease is a rare, clinical and pathologic disease entity of unknown etiology. Its main features are increased serum concentrations of IgG4 > 1,35 g/l, lymphocyte and IgG4+plasma-cell infiltration within tissues, fibrosis or sclerosis. The classical presentation of IgG4-RSD is pancreatitis which is combined with the involvement of biliary ducts in 74 percent of patients. Extrapancreatic manifestations include: abdominal or mediastinal lymphadenopathy; the involvement of salivary glands and lacrimal glands, kidneys, lung, retroperitoneum...
2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27756146/cancer-associated-thrombosis-and-palliative-care-an-interview-with-simon-noble
#4
Simon Noble
Simon Noble speaks to Sebastian Dennis-Beron, Commissioning Editor: Simon Noble is Clinical Professor in Palliative Medicine at Cardiff University and honorary consultant at the Royal Gwent Hospital in Newport. His main research interests are in the management of venous thromboembolism in advanced cancer, quality of life effects of venous thromboembolism and their therapies, clinical decision-making in venous thromboembolism management and the patient journey. He is involved at a national level in the delivery of evidence-based thromboprophylaxis for hospitalized patients through the All Party Thrombosis Group and sits on the NICE Guideline development group for thromboprophylaxis...
January 2017: Future Oncology
https://www.readbyqxmd.com/read/27741957/where-teachers-are-few-documenting-available-faculty-in-five-tanzanian-medical-schools
#5
Charles A Mkony, Ephata E Kaaya, Alex J Goodell, Sarah B Macfarlane
BACKGROUND: Faced with one of the lowest physician-to-population ratios in the world, the Government of Tanzania is urging its medical schools to train more physicians. The annual number of medical students admitted across the country rose from 55 in the 1990s to 1,680 approved places for the 2015/16 academic year. These escalating numbers strain existing faculty. OBJECTIVE: To describe the availability of faculty in medical schools in Tanzania. DESIGN: We identified faculty lists published on the Internet by five Tanzanian medical schools for the 2011/12 academic year and analyzed the appointment status, rank, discipline, and qualifications of faculty members...
2016: Global Health Action
https://www.readbyqxmd.com/read/27428874/quality-requirements-for-veterinary-hematology-analyzers-in-small-animals-a-survey-about-veterinary-experts-requirements-and-objective-evaluation-of-analyzer-performance-based-on-a-meta-analysis-of-method-validation-studies-bench-top-hematology-analyzer
#6
Andrea M Cook, Andreas Moritz, Kathleen P Freeman, Natali Bauer
BACKGROUND: Scarce information exists about quality requirements and objective evaluation of performance of large veterinary bench top hematology analyzers. OBJECTIVE: The study was aimed at comparing the observed total error (TEobs ) derived from meta-analysis of published method validation data to the total allowable error (TEa ) for veterinary hematology variables in small animals based on experts' opinions. Ideally, TEobs should be < TEa . METHODS: An online survey was sent to veterinary experts in clinical pathology and small animal internal medicine for providing the maximal allowable deviation from a given result for each variable...
September 2016: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/27413526/the-icet-a-survey-on-current-criteria-used-by-clinicians-for-the-assessment-of-central-adrenal-insufficiency-in-thalassemia-analysis-of-results-and-recommendations
#7
Vincenzo De Sanctis, Ashraf T Soliman, Heba Elsedfy, Alice Albu, Soad Al Jaouni, Saif Al Yaarubi, Salvatore Anastasi, Duran Canatan, Massimo Di Maio, Salvatore Di Maio, Mohamed El Kholy, Mehran Karimi, Doaa Khater, Yurdanur Kilinc, Su Han Lum, Nicos Skordis, Praveen Sobti, Iva Stoeva, Ploutarchos Tzoulis, Yasser Wali, Christos Kattamis
BACKGROUND: In March 2015, the International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescent Medicine (ICET-A) implemented a two-step survey on central adrenal insufficiency (CAI) assessment in TM patients and after analysis of the collected data, recommendations for the assessment of hypothalamic-pituitary- adrenal (HPA) axis in clinical practice were defined. METHODS: To ascertain the current practice for assessment of CAI in thalassemia, the Coordinator of ICET-A sent two questionnaires by email: i) The first to evaluate the current interpretation of basal serum cortisol level (first step) and ii) The second to assess the current usage of ACTH test and the variability in practice" (second step)...
2016: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/27413440/the-effect-of-paging-reminders-on-fellowship-conference-attendance-a-multi-program-randomized-crossover-study
#8
Joshua Smith, Lorenzo Zaffiri, Julie Clary, Tyler Davis, Gabriel T Bosslet
BACKGROUND: Educational conferences have long served as a foundation of medical education. Sending reminder text pages prior to the start of conferences is a method that may be employed to enhance conference attendance. OBJECTIVE: The goal of our study was to determine if routine text paging before regularly scheduled conferences improves attendance among fellows in 3 internal medicine programs. METHODS: A prospective, randomized, crossover study included 3 fellowship programs: pulmonary and critical care, cardiovascular disease, and hematology-oncology...
July 2016: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/27376752/-pruritus-in-systemic-diseases-common-and-rare-etiologies
#9
A E Kremer, T Mettang
Chronic pruritus is a symptom of various internal disorders. In contrast to dermatological diseases, pruritus does not present with primary skin alterations in these patients. However, intense scratching may cause secondary skin changes such as abrasion, excoriation, prurigo nodularis, or in rare cases even scaring. The most common internal medicine causes for chronic pruritus are chronic kidney disease, hepatobiliary and hematological disorders as well as adverse drug reactions. Pruritus is less commonly seen in patients with endocrine or metabolic diseases, malabsorption syndromes, infectious diseases and solid tumors...
August 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27342424/identification-of-high-resource-utilizing-patients-on-internal-medicine-hospital-services
#10
David W Walsh, Molly C McVey, Abigal Gass, Jingwen Zhang, Patrick D Mauldin, Don C Rockey
In order to provide high quality, cost-efficient care, it is critical to understand drivers of the cost of care. Therefore, we sought to identify clinical variables associated with high utilization (cost) in patients admitted to medical services and to develop a robust model to identify high utilization patients. In this case-control analysis, cases were identified as the 200 most costly patients admitted to internal medicine/internal medicine subspecialty services using our institution's computerized clinical data warehouse over a 7-month time period (November 1, 2012-May 31, 2013)...
October 2016: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/27275266/a-very-rare-presentation-of-multiple-myeloma-unilateral-raccoon-eye
#11
Ceyhun Varım, Hasan Ergenc, Mehmet Sevki Uyanık, Tezcan Kaya, Ahmet Nalbant, Cengiz Karacaer, Cenk Sunu, Ali Tamer
Multiple myeloma (MM), the second most common hematological malignancy, is caused by the accumulation of monoclonal plasma cells in bone marrow. It accounts for 10-15% of deaths from hematological malignancies and approximately 2% of deaths from cancer. The median age at presentation is 70 years old. The diagnosis is incidental in 30% of cases. MM is often discovered through routine blood screening with a large gap between the total protein and the albumin levels. Two thirds of patients complain of bone pain, especially lower back pain...
September 15, 2015: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27218428/resilience-of-internal-medicine-house-staff-and-its-association-with-distress-and-empathy-in-an-oncology-setting
#12
Daniel C McFarland, Andrew Roth
CONTEXT: Resilience is a beneficial trait for resident physicians who are exposed to adversity through their work with patients. Inpatient hematology-oncology produces vicarious trauma for physicians in training. Physician distress and empathy influence patient care and may be associated with respectively lower and greater levels of resilience. METHODS: We collected measures of resilience (Connor-Davidson Resilience Scale), distress (Impact of Events Scale - Revised), and rotation-specific information (e...
May 24, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27152483/identifying-existing-choosing-wisely-recommendations-of-high-relevance-and-importance-to-hematology
#13
Lisa K Hicks, Anita Rajasekhar, Harriet Bering, Kenneth R Carson, Judith Kleinerman, Vishal Kukreti, Alice Ma, Brigitta U Mueller, Sarah H O'Brien, Julie A Panepinto, Marcelo C Pasquini, Ravi Sarode, William A Wood
Choosing Wisely (CW) is a medical stewardship initiative led by the American Board of Internal Medicine Foundation in collaboration with professional medical societies in the United States. In an effort to learn from and leverage the work of others, the American Society of Hematology CW Task Force developed a method to identify and prioritize CW recommendations from other medical societies of high relevance and importance to patients with blood disorders and their physicians. All 380 CW recommendations were reviewed and assessed for relevance and importance...
August 2016: American Journal of Hematology
https://www.readbyqxmd.com/read/27052648/cns-infections-in-patients-with-hematological-disorders-including-allogeneic-stem-cell-transplantation-guidelines-of-the-infectious-diseases-working-party-agiho-of-the-german-society-of-hematology-and-medical-oncology-dgho
#14
M Schmidt-Hieber, G Silling, E Schalk, W Heinz, J Panse, O Penack, M Christopeit, D Buchheidt, U Meyding-Lamadé, S Hähnel, H H Wolf, M Ruhnke, S Schwartz, G Maschmeyer
Infections of the central nervous system (CNS) are infrequently diagnosed in immunocompetent patients, but they do occur in a significant proportion of patients with hematological disorders. In particular, patients undergoing allogeneic hematopoietic stem-cell transplantation carry a high risk for CNS infections of up to 15%. Fungi and Toxoplasma gondii are the predominant causative agents. The diagnosis of CNS infections is based on neuroimaging, cerebrospinal fluid examination and biopsy of suspicious lesions in selected patients...
July 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/26937313/provider-perspective-on-integrative-medicine-for-pediatric-sickle-cell-disease-related-pain
#15
Caitlin M Neri, Tishra Beeson, Holly Mead, Deepika S Darbari, Emily Riehm Meier
OBJECTIVE: Integrative medicine (IM) approaches are sometimes used to manage sickle cell disease (SCD)-related pain. The purpose of this research is to (1) understand provider perspective towards the use of IM for pain in children with SCD at a large urban children's hospital and (2) provide recommendations on how to better promote IM for children and adolescents with SCD. METHODS: After approval from the institutional review board, a qualitative case study approach was used with criterion-type purposeful sampling to select providers from the division of hematology to adequately inform the study...
January 2016: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/26897634/medical-knowledge-assessment-by-hematology-and-medical-oncology-in-training-examinations-are-better-than-program-director-assessments-at-predicting-subspecialty-certification-examination-performance
#16
Frances A Collichio, Brian J Hess, Elaine A Muchmore, Lauren Duhigg, Rebecca S Lipner, Steven Haist, Janine L Hawley, Carol A Morrison, Charles P Clayton, Marilyn J Raymond, Karen M Kayoumi, Scott D Gitlin
The Accreditation Council for Graduate Medical Education's Next Accreditation System requires training programs to demonstrate that fellows are achieving competence in medical knowledge (MK), as part of a global assessment of clinical competency. Passing American Board of Internal Medicine (ABIM) certification examinations is recognized as a metric of MK competency. This study examines several in-training MK assessment approaches and their ability to predict performance on the ABIM Hematology or Medical Oncology Certification Examinations...
February 20, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/26875468/-clinical-features-and-antibiotic-resistance-of-escherichia-coli-bloodstream-infections-in-children
#17
Shaoying Li, Lingyun Guo, Linlin Liu, Fang Dong, Gang Liu
OBJECTIVE: To analyze risk factors, clinical features, outcomes and antibiotic resistance of Escherichia coli(E.coli) causing bloodstream infections in children. METHOD: All inpatients with E. coli positive blood culture in Beijing Children's Hospital from January 2012 to May 2014 were enrolled; 112 cases were included, 66 cases (58.9%) were male, and 46 cases(41.1%) were female. Age range was 2 days to 16 years. Among them, 43 cases (38.4%) were neonates, 19 cases (17...
February 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/26814071/-training-evaluation-of-clinical-laboratory-excellence-for-technologists-from-some-county-and-township-hospitals-in-31-provinces-of-china
#18
Hong Shang, Wei Cui, Man Zhang, Hongying Yang, Ziyong Sun, Yong Duan, Ming Chen, Hong Yuan, Ming Guan, Shufang Zhang, Mei Jia
OBJECTIVE: To improve clinical testing excellence through a large scale training project targeting laboratory operators at China's county and township hospitals. METHODS: The Chinese Society of Laboratory Medicine launched the "Clinical Laboratory Standards and Training Support Project" from 2010 to 2013. The project innovatively created a model of partnership between government, professional association, individual hospitals and other social forces. A survey before training was conducted in 445 county-hospital laboratories in 31 provinces...
September 22, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/26789902/images-in-clinical-medicine-spontaneous-retropharyngeal-hematoma
#19
Noah Ditkofsky, Tarek Hanna
A 56-year-old man presented to the emergency department with a 5-hour history of throat swelling and pain and difficulty breathing that was exacerbated by supine positioning; he had not had any obvious antecedent trauma. His medical history included prostate cancer, hypertension, hyperlipidemia, deep-vein thrombosis, and stroke. Medications included warfarin (presumably for deep-vein thrombosis), antihypertensive agents, and a statin. He was afebrile, and the physical examination was notable for minor swelling of the posterior oropharynx...
January 21, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/26776456/acute-empathy-decline-among-resident-physician-trainees-on-a-hematology-oncology-ward-an-exploratory-analysis-of-house-staff-empathy-distress-and-patient-death-exposure
#20
Daniel C McFarland, Adriana K Malone, Andrew Roth
OBJECTIVE: A reason for empathy decline during medical training has not been fully elucidated. Empathy may decrease acutely during an inpatient hematology-oncology rotation because of the acuity of death exposures. This study aimed to explore physician trainee empathy, distress, death exposures, and their attributed meaning for the trainee. METHODS: Internal medicine interns and residents at a single academic center were evaluated before and after hematology-oncology ward rotations using Interpersonal Reactivity Index for empathy, previously cited reasons for empathy decline, Impact of Event Scale-Revised for distress, death exposures (no...
January 18, 2016: Psycho-oncology
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