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https://www.readbyqxmd.com/read/27928470/co2bold-assessment-of-moyamoya-syndrome-validation-with-single-photon-emission-computed-tomography-and-positron-emission-tomography-imaging
#1
Alain Pellaton, Philippe Bijlenga, Laurie Bouchez, Victor Cuvinciuc, Isabelle Barnaure, Valentina Garibotto, Karl-Olof Lövblad, Sven Haller
AIM: To compare the assessment of cerebrovascular reserve (CVR) using CO2BOLD magnetic resonance imaging (MRI) vs positron emission tomography (PET) and single photon emission computed tomography (SPECT) as reference standard. METHODS: Ten consecutive patients (8 women, mean age of 41 ± 26 years) with moyamoya syndrome underwent 14 pre-surgical evaluations for external-internal carotid artery bypass surgery. CVR was assessed using CO2BOLD and PET (4)/SPECT (11) with a maximum interval of 36 d, and evaluated by two experienced neuroradiologists...
November 28, 2016: World Journal of Radiology
https://www.readbyqxmd.com/read/27919270/delayed-hyperbaric-oxygen-therapy-for-air-emboli-after-open-heart-surgery-case-report-and-review-of-a-success-story
#2
Eva Niyibizi, Guillaume Elyes Kembi, Claude Lae, Rodrigue Pignel, Tornike Sologashvili
BACKGROUND: The current case describes a rare diagnosis of iatrogenic air emboli after elective cardiopulmonary bypass that was successfully treated with delayed hyperbaric oxygen therapy, with good clinical evolution in spite of rare complications. CASE PRESENTATION: A 35 years old male was admitted to the intensive care unit (ICU) for post-operative management after being placed on cardiopulmonary bypass (CPB) for an elective ventricular septal defect closure and aortic valvuloplasty...
December 5, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27891675/surgical-management-of-infective-endocarditis-complicated-by-ischemic-stroke
#3
Kevin E Hodges, Syed T Hussain, William J Stewart, Gosta B Pettersson
Embolism to the central nervous system is a frequent and important complication of infective endocarditis. While early surgery improves outcomes in many groups of patients with infective endocarditis, ischemic stroke secondary to septic embolism carries the risk of hemorrhagic transformation and neurological deterioration with heparinization and cardiopulmonary bypass. We review the literature regarding the surgical management of infective endocarditis in patients with cerebral emboli.
November 27, 2016: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/27891422/panvascular-disease-in-familial-hypercholesterolaemia-treated-with-endovascular-simultaneous-bilateral-carotid-stenting
#4
Anand Alurkar, Lakshmi Sudha Prasanna Karanam, Shripal Shah, Pandurang Mare
Familial Hypercholesterolaemia (FH) is a monogenic autosomal dominant disorder affecting 1 in 500 individuals. We report a case of 32-year-old female with FH, previously not on any treatment, who presented with recurrent bilateral Middle Cerebral Artery (MCA) territory strokes and dyspnoea on exertion due to severe panvascualar disease involving descending aorta, innominate, subclavian, common carotid, internal carotid and coronary vessels. Her complete clinical work up was done and was started on lipid lowering drug treatment and low calorie diet...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27885823/novel-functionalization-strategies-of-polymeric-nanoparticles-as-carriers-for-brain-medications
#5
Corinne Portioli, Michele Bovi, Donatella Benati, Marta Donini, Massimiliano Perduca, Alessandro Romeo, Stefano Dusi, Hugo L Monaco, Marina Bentivoglio
For targeted brain delivery, nanoparticles (NPs) should bypass the blood-brain barrier (BBB). Novel functionalization strategies, based on low-density lipoprotein receptor (LDLR) binding domain, have been here tested to increase the brain targeting efficacy of poly d,l-lactic-co-glycolic acid (PLGA) NPs, biodegradable and suited for biomedical applications. Custom-made PLGA NPs were functionalized with an apolipoprotein E modified peptide (pep-apoE) responsible for LDLR binding, or with lipocalin-type prostaglandin-d-synthase (L-PGDS), highly expressed in the brain...
November 5, 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27876287/mid-term-outcomes-of-common-congenital-heart-defects-corrected-through-a-right-subaxillary-thoracotomy
#6
Guoying An, Hongyu Zhang, Shanguang Zheng, Weixin Wang, Liming Ma
OBJECTIVE: To evaluate the mid-term outcomes of the correction of various congenital heart defects through a right subaxillary thoracotomy. METHODS: Between June 2004 and April 2014, all eligible patients were those with a common congenital heart defect corrected via an approach through a right subaxillary thoracotomy. There were 836 patients (male 417, female 419; median age, 3.5 years; median weight 13.6kg) with ventricular septal defect (VSD) closure (523 patients), atrial septal defect (ASD) closure (235 patients), partial atrioventricular canal (PAVC) correction (55 patients), mild tetralogy of Fallot (TOF) (23 patients)...
February 17, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27875660/successful-use-of-targeted-temperature-management-after-repair-of-myocardial-rupture-from-blunt-chest-trauma-a-case-report
#7
Wook-Jin Choi, Yun Seok Kim, Jung Seok Hong, Jeong Won Kim
Targeted temperature management (TTM) improves survival and neurological outcome after nontraumatic cardiac arrest. However, TTM is not used widely after traumatic cardiac arrest because of concerns that it might exacerbate bleeding. We report the use of postarrest TTM after repair of blunt myocardial rupture. A 48-year-old man was admitted after being rescued from a major traffic accident by the local emergency service. Focused sonography showed pericardial fluid without cardiac tamponade. Computed tomography showed a large hematoma in the anterior mediastinum associated with hemopericardium...
November 22, 2016: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/27857034/superficial-temporal-artery-to-middle-cerebral-artery-bypass-with-interposed-saphenous-vein-graft-in-patients-with-atherosclerotic-internal-carotid-artery-occlusive-disease-and-impaired-cerebral-hemodynamics
#8
Petr Galkin, Artem Gushcha, Andrey Chechetkin, Irina Krotenkova
BACKGROUND: The aim of this study was to evaluate the efficacy of interposed saphenous vein graft (SVG) usage during extracranial-intracranial (EC-IC) bypass surgery in patients with cerebral ischemia and appropriate donor artery absence. METHODS: Since October 2010 till January 2014, 62 EC-IC bypass surgeries were applied in 60 patients. In nineteen patients SVG was used to create low-flow bypasses between superficial temporal artery trunk and cortical segment of middle cerebral artery...
February 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27852286/the-carotid-and-middle-cerebral-artery-occlusion-surgery-study-cmoss-a-study-protocol-for-a-randomised-controlled-trial
#9
Yan Ma, Yuxiang Gu, Xiaoguang Tong, Jiyue Wang, Dong Kuai, Donghai Wang, Jun Ren, Lian Duan, Aili Maimaiti, Yiling Cai, Yujie Huang, Xiaojian Wang, Yi Cao, Chao You, Jiasheng Yu, Liqun Jiao, Feng Ling
BACKGROUND: Patients with symptomatic internal carotid artery (ICA) or middle cerebral artery (MCA) occlusion with haemodynamic insufficiency are at high risk for recurrent stroke when treated medically. METHODS: The Carotid or Middle cerebral artery Occlusion Surgery Study (CMOSS) trial is an ongoing, government-funded, prospective, multicentre, randomised controlled trial. The CMOSS will recruit 330 patients with symptomatic ICA or MCA occlusion (parallel design, 1:1 allocation ratio) and haemodynamic insufficiency...
November 16, 2016: Trials
https://www.readbyqxmd.com/read/27847780/recurrent-carotid-cavernous-fistula-originating-from-a-giant-cerebral-aneurysm-after-placement-of-a-covered-stent
#10
Jung Wook Baek, Sung Tae Kim, Young Seo Lee, Young-Gyun Jeong, Hae Woong Jeong, Jin Wook Baek, Jung Hwa Seo
We report the case of a recurrent carotid cavernous fistula (CCF) originating from a giant cerebral aneurysm (GCA) after placement of a covered stent. A 47-year-old woman presented with sudden onset of severe headache, and left-sided exophthalmos and ptosis. Cerebral angiography revealed a CCF caused by rupture of a GCA in the cavernous segment of the left internal carotid artery. Two covered stents were placed at the neck of the aneurysm. The neurological symptoms improved at first, but were aggravated in the 6 months following the treatment...
September 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/27847771/emergent-double-barrel-bypass-shortly-after-intravenous-administration-of-recombinant-tissue-plasminogen-activator-for-acute-ischemic-stroke
#11
Joon-Ho Choi, Hyun-Seok Park
Although intravenous recombinant tissue plasminogen activator (IV rt-PA) is effective in many cases of acute ischemic stroke, the neurologic symptoms can worsen after IV rt-PA because of sustained vessel occlusion. For such cases, several reperfusion modalities are available, including intra-arterial thrombolysis (IAT), carotid endarterectomy, and superficial temporal artery-middle cerebral artery (STA-MCA) bypass. Invasive procedures, such as major surgery, should be generally avoided within 24 hours after the administration of IV rt-PA...
September 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/27847768/the-efficacy-of-single-barrel-superficial-temporal-artery-middle-cerebral-artery-bypass-in-treatment-of-adult-patients-with-ischemic-type-moyamoya-disease
#12
Mahnjeong Ha, Chang Hwa Choi, Jae Il Lee, Seung Heon Cha, Sang Weon Lee, Jun Kyeung Ko
OBJECTIVE: So far, there is no study answering the question of which type of surgical technique is practically the most useful in the treatment of adult patients with ischemic type moyamoya disease (MMD). We evaluated the efficacy of single barrel superficial temporal artery (STA)-middle cerebral artery (MCA) bypass in the treatment of adult patients with ischemic type MMD by retrospectively collecting clinical and radiological data. MATERIALS AND METHODS: A retrospective review identified 31 adult patients who underwent 43 single barrel STA-MCA bypass procedures performed for treatment of ischemic-type MMD between 2006 and 2014...
September 2016: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/27843336/treatment-of-bleeding-in-acquired-hemophilia-a-with-the-proper-administration-of-recombinant-activated-factor-vii-single-center-study-of-7-cases
#13
Makoto Saito, Minoru Kanaya, Koh Izumiyama, Akio Mori, Tatsuro Irie, Masanori Tanaka, Masanobu Morioka, Masahiro Ieko
Recombinant activated factor VII (rFVIIa) is the bypassing agent used in the first-line hemostatic therapy for acquired hemophilia A (AHA); however, the occurrence of thrombotic complications in rFVIIa-treated AHA patients was recently reported to be 2.9-6.5%. Therefore, the investigation of the proper administration of rFVIIa for AHA is needed. In the present study, we retrospectively investigated the clinical features of AHA with regards to the use of rFVIIa (presence or absence of use and total amount) in 7 AHA patients encountered in our department for 7 years between January 2008 and December 2014...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27836703/surgical-treatment-of-traumatic-intracranial-aneurysms-experiences-at-a-single-center-over-30-years
#14
Seung-Hoon Jung, Sung-Hyun Kim, Tae-Sun Kim, Sung-Pil Joo
OBJECTIVE: Traumatic intracranial aneurysms (tIA) are rare and are associated with high rates of morbidity and mortality. We describe our experiences with tIA at our institution. METHODS: We retrospectively reviewed records from patients who underwent treatment for tIA between January 1986 and December 2015. RESULTS: Data from 5,532 patients diagnosed with cerebral aneurysms between January 1986 and December 2015 in our hospital were reviewed...
November 8, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27834592/the-anterior-temporal-artery-an-underutilized-but-robust-donor-for-revascularization-of-the-distal-middle-cerebral-artery
#15
Ali Tayebi Meybodi, Michael T Lawton, Dylan Griswold, Pooneh Mokhtari, Andre Payman, Arnau Benet
OBJECTIVE The anterior temporal artery (ATA) supplies an area of the brain that, if sacrificed, does not cause a noticeable loss of function. Therefore, the ATA may be used as a donor in intracranial-intracranial (IC-IC) bypass procedures. The capacities of the ATA as a donor have not been studied previously. In this study, the authors assessed the feasibility of using the ATA as a donor for revascularization of different segments of the distal middle cerebral artery (MCA). METHODS The ATA was studied in 15 cadaveric specimens (8 heads, excluding 1 side)...
November 11, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27832618/-indocyanine-green-videoangiography-guided-target-bypass-for-surgical-trapping-of-distal-middle-cerebral-artery-aneurysm-a-technical-case-report
#16
Takaya Yasuda, Hitoshi Fukuda, Masanori Kinosada, Masaki Chin, Sen Yamagata
Intraoperative indocyanine green(ICG)videoangiography is simple, less invasive, and enables real-time observation of hemodynamics during neurovascular surgery. In this article, we describe a case of ruptured distal middle cerebral artery aneurysm, which was unclippable and required parent artery occlusion with extracranial-intracranial bypass. Under temporary clipping of the proximal vessel, ICG videoangiography demonstrated the proper target vessel for bypass through delayed and retrograde filling of the dye...
November 2016: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/27829638/comparison-of-percutaneous-coronary-intervention-versus-coronary-artery-bypass-graft-in-aged-patients-with-unprotected-left-main-artery-lesions
#17
Zhonghai Wei, Jun Xie, Kun Wang, Lina Kang, Qing Dai, Jian Bai, Biao Xu
There is still much debate about revascularization strategies in aged patients with unprotected left main coronary artery (UPLM) lesions. This study compared the outcomes of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) in this population.A total of 126 patients older than 60 years of age with LM lesions who underwent revascularization in our hospital from January 2012 to December 2013 were followed up for an average of 15.2 months. The cumulative incidence of major adverse cardiac and cerebral events (MACCE) was estimated by Kaplan-Meier plots...
November 9, 2016: International Heart Journal
https://www.readbyqxmd.com/read/27825691/long-term-outcomes-of-open-arch-repair-after-a-prior-aortic-operation-our-experience-in-154-patients
#18
Roberto Di Bartolomeo, Paolo Berretta, Antonio Pantaleo, Giacomo Murana, Mariano Cefarelli, Jacopo Alfonsi, Giuseppe Barberio, Alessandro Leone, Luca Di Marco, Davide Pacini
BACKGROUND: This study assessed the early and long-term results of arch operations performed after a prior aortic operation. METHODS: From 1994 to 2014, 154 consecutive patients (mean age, 59.7 years) underwent an aortic arch repair, after a previous aortic operation, at our institution. Antegrade selective cerebral perfusion was used in all cases. Chronic postdissection aortic aneurysm (87 [56.5%]) and degenerative aneurysm (43 [27.9%]) represented the most common indications for surgical intervention...
November 5, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27815377/endovascular-recanalization-of-the-common-carotid-artery-in-a-patient-with-radio-induced-chronic-occlusion
#19
Lorena Nico, Giacomo Cester, Federica Viaro, Claudio Baracchini, Francesco Causin
Recanalization of chronic occlusion of the common carotid artery (CCA) in patients with a history of neck irradiation is challenging, both for vascular surgeons and interventional neuroradiologists. We describe a case of successful stenting of radio induced chronic occlusion of the right CCA in a 41-year-old patient with neurological deterioration and minor stroke due to cerebral hypoperfusion caused by concomitant bilateral arterial occlusions. Direct surgery and surgical bypass were considered contraindicated...
November 4, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27813463/bypass-surgery-for-complex-middle-cerebral-artery-aneurysms-an-algorithmic-approach-to-revascularization
#20
Ali Tayebi Meybodi, Wendy Huang, Arnau Benet, Olivia Kola, Michael T Lawton
OBJECT Management of complex aneurysms of the middle cerebral artery (MCA) can be challenging. Lesions not amenable to endovascular techniques or direct clipping might require a bypass procedure with aneurysm obliteration. Various bypass techniques are available, but an algorithmic approach to classifying these lesions and determining the optimal bypass strategy has not been developed. The objective of this study was to propose a comprehensive and flexible algorithm based on MCA aneurysm location for selecting the best of multiple bypass options...
November 4, 2016: Journal of Neurosurgery
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