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vertigo evaluation

Amanda Phillips, Ralf Strobl, Eva Grill, Gunter Laux
PURPOSE: To date, there is little information on the utilization of anticholinergic and sedative (AS) medications to vertigo or dizziness (VoD) patients in the German primary care setting. The objective of this study was to evaluate AS medication use and its association with VoD within the German primary care setting. METHODS: Cases with VoD from the CONTENT (CONTinuous morbidity registration Epidemiologic NeTwork) database were 1:1 matched to controls on age, sex, and comorbidities by propensity score matching...
June 13, 2018: Pharmacoepidemiology and Drug Safety
Mendel Jansen, Jeanne Mendell, Alexander Currie, James Dow, Ling He, Domenico Merante, Victor Dishy, Hitoshi Ishizuka, Hamim Zahir
Four randomized, double-blind, placebo-controlled, 4-period drug-drug interaction studies were conducted in healthy subjects to evaluate the pharmacokinetic and pharmacodynamic (PD) interactions between mirogabalin and commonly used central nervous system depressants. Mirogabalin or placebo was administered alone or with single-dose lorazepam, zolpidem, tramadol, ethanol, or interacting drug placebo. Safety was assessed and serial samples for pharmacokinetic parameters were collected for up to 48 hours postdose...
June 5, 2018: Clinical Pharmacology in Drug Development
C R Gordon, R Tamir, R Furas, C Klein, R Roth
OBJECTIVE: A pilot study to assess the efficacy and safety of a novel specs device developed to alleviate chronic dizziness using eyeglasses with referential marks fixed on the lenses. MATERIALS AND METHODS: Forty patients with stable symptoms of chronic dizziness for more than 3 months participated in a 4-week, double-blind, randomized treatment with Active-Specs or Sham-Specs. Efficacy was assessed using validated semiquantitative scales and questionnaires of vertigo, dizziness and anxiety...
June 3, 2018: Acta Neurologica Scandinavica
Enrique García Zamora, Pedro Espírito-Santo Araújo, Vanesa Pérez Guillén, María Fernanda Vargas Gamarra, Victoria Fornés Ferrer, Magdalena Courel Rauch, Herminio Pérez Garrigues
HYPOTHESIS: The knowledge of vibration-induced nystagmus test (SVINT) values in the normal population is highly relevant to provide a rapid orientation on the diagnosis attitude in a patient with vertigo. BACKGROUND: Although mastoid bone vibration should only induce nystagmus in the presence of vestibular asymmetry, it has also been reported in normal individuals raising doubts as to how to interpret the SVINT. To date, no population studies involving the use of the SVINT and that establish normative values have been published...
June 1, 2018: European Archives of Oto-rhino-laryngology
L A Rodríguez de Antonio, I García Castañón, M J Aguilar-Amat Prior, I Puertas, I González Suárez, C Oreja Guevara
OBJECTIVES: To describe non-relapse-related emergency consultations of patients with multiple sclerosis (MS): causes, difficulties in the diagnosis, clinical characteristics, and treatments administered. METHODS: We performed a retrospective study of patients who attended a multiple sclerosis day hospital due to suspected relapse and received an alternative diagnosis, over a 2-year period. Demographic data, clinical characteristics, final diagnosis, and treatments administered were evaluated...
May 26, 2018: Neurología: Publicación Oficial de la Sociedad Española de Neurología
Akihiko Yoshimura, Kenjiro Sawada, Tomoyuki Sasano, Hiromasa Kuroda, Katsumi Kozasa, Erika Nakatsuka, Koji Nakamura, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura
Loss of ovarian function by the treatment for gynecological malignancy results in a drastic decrease of estrogen causing physical and mental symptoms. The purpose of this study is to evaluate the effect of Japanese Kampo Kamikihito (KKT) and Kamishoyosan (KSS) on menopausal symptoms in gynecological cancer patients. Patients who had menopausal symptoms after gynecologic malignancy treatment were enrolled and randomly divided into a KKT or a KSS group. Kupperman Menopausal Index (KI) questionnaires were obtained before tumor treatment, at baseline, and at 4 and 8 weeks...
2018: Obstetrics and Gynecology International
X Gu, F L Dong, J H Gu
Objective: To study whether serum 25-hydroxy vitamin D can be used as an independent indicator of prognosis in patients with benign paroxysmal positional vertigo. Method: Two hundred and two patients with BPPV were collected and divided into vitamin D deficiency group and control group according to their serum 25-OHD level. The severity of the symptoms and the recurrence rate were compared between the two groups. Result: Compared with the control group, patients with vitamin D deficiency group showed severer symptoms, either in longer duration of vertigo, lower success rate of repositioning maneuver treatment at the first time, or higher recurrence rate within six months...
June 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
L B Sun, Z Y Zheng, B Q Wang, W Y Yu, J Yang, W J Guo, H J Ren
Objective: To explore the curative effect and quality life of the vestibular rehabilitation training on residual dizziness after successful canalith repositioning maneuvers in patients with benign paroxysmal positional vertigo (BPPV). Method: Residual dizziness after successful canalith repositioning maneuvers in patients with BPPV were enrolled in our study. They were randomized into three groups, the control group A were no disposition which include 32 patients, the intervention group B were guided to self rehabilitation training which include 33 patients, the control group C were guided to Brandt Daroff training which include 33 patients...
June 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Q Yuan, Y Zhang, D L Liu, X L Zhang, Q F Zhang
Objective: To review the results of caloric test and the video head impulse test (vHIT) in a cohort of VM patients and assessed the value of each for predicting the prognosis in VM patients. Method: A retrospective analysis was performed on VM patients in our vertigo clinic, vestibular function were assessed by caloric test and vHIT at the initial visit and 6 months after treatment. Complete response (CR) was defined as no need for continued medication, uncomplete response (UR) as improved symptoms but need for continued medication, no symptomatic improvement...
July 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
S Z Zou, J R Li, S Y Tian, J Ju, M Y Jia
Objective: To observe the short-term efficacy of modified Semont maneuver for posterior canal benign paroxysmal positional vertigo (PC-BPPV) Method: This was a prospective randomized controlled trial on 130 PC-BPPV patients. Subjects were randomized divided into two groups: modified Semont (65 patients),and Epley(65 patients).Each maneuver was repeated twice,and the presence of sequelae,nystagmus and vertigo on positional testing were evaluated 3rd day and 1 week after treatment. Result: Five patients were lost to follow up (all five in the modified Semont group),and three patients failed to complete treatment (all three in the Epley group)...
October 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y X Chen, X Sun, L Y Shi, N T Wang, X Peng, N Wang, C L Ren, X Z Shan
Objective: To analyze the clinical characteristics of patients with cerebellar and brainstem infarction who initially presented with isolated vertigo to avoid misdiagnosing of this disease. Method: Eleven patients with cerebellar and brainstem infarction who initially presented with isolated vertigo treated in our clinic between January 2014 and September 2017 were reviewed and the clinical characteristics and imaging presentation of the patients were evaluated. Result: Vertigo as the first attack was in 5 cases, recurrent attacks was in 6 cases,10 cases were with vascular risk factors except for 1 case, initially diagnosed as vestibular neuritis was 4 cases, Meniere's disease was 1 case, posterior circulartion ischemia was 1 case,and unknown causes was 5 cases; delayed neurological symptoms and signs occurring was 4 cases, but not in other cases; finally determined by brain MRI as acute cerebellar infarction was 5 cases, brainstem infarction was 5 cases, and concurrent cerebellar and brainstem infarction was 1 case...
April 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Y J Li, X R Xu
Vestibular rehabilitation is one of the treatments of vertigo, which major based on vestibular exercise. Unlike general exercise, it is a highly specialized designed method without medication or traumatic. Vestibular rehabilitation includes peripheral rehabilitation,central rehabilitation, alternative rehabilitation, visual conflict rehabilitation and fall prevention rehabilitation. The cross-coupling mechanism of vestibular reflex is the basis of vestibular compensation. The characteristics of visual reflex and the proprioception mediated cervical reflex are the foundation of alternative rehabilitation, and cognitive mechanism is the basis of all kinds of vestibular rehabilitation...
October 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Eric X Wei, Yuri Agrawal
Recent evidence has shown that individuals with vestibular impairment have higher rates of self-reported driving difficulty compared with individuals without vestibular impairment. However, it is unknown whether individuals with vestibular impairment are more likely to be involved in motor vehicle accidents. We used data from the 2016 National Health Interview Survey of U.S. adults to evaluate whether individuals with vestibular vertigo are more likely to experience motor vehicle accidents relative to individuals without vestibular vertigo...
May 18, 2018: Ear and Hearing
Francesco Comacchio, Marta Mion
The goal of the present study was to describe a case of perilymphatic fistula (PLF) of the round window (RW) that occurred after sneezing, along with a review of the literature. We report a case of PLF of RW, which was provoked by sneezing, and its consequent medical and surgical treatments. With respect to the review of the literature, articles were initially selected based on their titles or abstracts, followed by methodological evaluation. The patient underwent an explorative tympanotomy (ET) with packaging of RW with the pericondrium, following which the patient's complaints regarding vertigo and imbalance disappeared, but the severe sensorineural hearing loss persisted...
April 2018: Journal of International Advanced Otology
Biao Chen, Ying Shi, Yue Gong, Jing Yuan Chen, Dan Mo Cui, Ting Liu, Jie Wang, Xin Ping Hao, Yong Xin Li
Objective: To investigate the long-term efficacy of endolymphatic sac mastoid drainage for Ménière disease. Method: Data from 26 patients diagnosed with MD strictly meeting the criteria issued by " Guideline of diagnosis and treatment of Meniere disease(2017)" from 2006 to 2015 were analyzed in this study.Endolymphatic sac mastoid shunt surgery was performed for each patient.The therapeutic effect was evaluated against the " Guideline of diagnosis and treatment of Meniere disease(2017)"...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Jie Zeng, Hong Ming Huang, Xiao Qian Wang, Kai Bang Zhong, Pei Na Wu
Objective: To analyze the functional change of horizontal semicircular canals after cochlear implantation. Method: Eighteen patients were enrolled in this study.Their vestibular function was evaluated by using the caloric test and video head impulse test before and one week,one month after CI surgery,respectively.The unilateral weakness(UW),slow phase velocity(SPV)in caloric test and gain in video head impulse test(vHIT-G)were observed.Caloric test was abnormal when UW>25% or SPV mean<6°/s,while vHIT was abnormal when vHIT-G<0...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Marzena Bielińska, Anna Polaczkiewicz, Piotr Pietkiewicz, Jarosław Miłoński, Jurek Olszewski
INTRODUCTION: The aim of the study was to evaluate concurrent recording of ENG and VNG measurements in selected diagnostic tests in healthy subjects so as to explore potential sensitivity and applicability of this kind of testing in the diagnostics of vertigo. MATERIAL AND METHODS: The study was carried out in 50 healthy subjects including 24 women and 26 men aged 20-22 (mean age of 20.5 years) reporting no otorhinolaryngological organ-related complaints and no history of any balance disorders or vertigo...
April 30, 2018: Otolaryngologia Polska
Montaser Abdel-Salam, Osama G Abdel-Naby Awad, Mohamed El-Badry, Ahmed Ibrahim, Mahmoud Hosny Ibrahiem
OBJECTIVE: Human menopausal gonadotropin (HMG) is one of the commonest drugs used for ovarian stimulation with no reports on the audio-vestibular system. This study aims to examine HMG on the hearing profile of patients planning intracytoplasmic sperm injection (ICSI). METHODS: This prospective study was conducted from June 2016 to June 2017 in a tertiary referral hospital. The audio-vestibular system of a total of 30 patients was evaluated using pure tone audiometry, distortion product otoacoustic emissions (DPOAEs in the form of a DP-gram) and Vestibular-evoked myogenic potential (VEMP) immediately before therapy and at the day 10 after therapy...
May 7, 2018: Auris, Nasus, Larynx
Inés Sánchez-Sellero, Elena San-Román-Rodríguez, Sofía Santos-Pérez, Marcos Rossi-Izquierdo, Andrés Soto-Varela
OBJECTIVES: Dietary changes are useful in the management of Menière's disease; regarding alcohol, many clinicians recommend to avoid or reduce its consumption. However, there are no researches aimed to evaluate whether habitual alcohol consumption is more prevalent and/or more intense in patients with Menière's disease. METHODS: Cross-sectional, observational, case-control study, including three groups: patients with Menière's disease, patients with vertigo of other origins, and control subjects...
May 7, 2018: Nutritional Neuroscience
Yi Zhang, Yuzheng Du
OBJECTIVE: Based on the western medication, to evaluate the advantages in the morning blood pressure treated with acupuncture at Fengchi (GB 20) and Neck-Jiaji (EX-B 2) combined with acupuncture technique for activating blood circulation, eliminating wind and regulating the liver and spleen in the patients with essential hypertension. METHODS: A total of 90 patients of essential hypertension of the mild and moderate degrees were randomized into a medication group (30 cases, 3 dropping), No...
April 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
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