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https://www.readbyqxmd.com/read/28077250/role-of-video-head-impulse-test-in-lateralization-of-vestibulopathy-comparative-study-with-caloric-test
#1
Pona Park, Joo Hyun Park, Ji Soo Kim, Ja-Won Koo
OBJECTIVE: To evaluate the lateralization value of video head-impulse test (vHIT) for the diagnosis of vestibulopathy and to analyze cases showing dissociated results with caloric test. METHODS: In total, 19 healthy volunteers and 92 dizzy patients who underwent both a caloric test and a vHIT were enrolled. Patients were divided into two groups depending on their fluctuating pattern of vertigo. The vestibulo-ocular reflex (VOR) gain and gain asymmetry (GA) of a vHIT as well as unilateral weakness (UW) and the sum of the slow-phase velocities (SPVs) of warm and cold irrigation of the same side were compared...
January 8, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28063321/clinical-implication-of-cervical-vestibular-evoked-myogenic-potentials-in-benign-paroxysmal-positional-vertigo
#2
Mun Young Chang, Ji Ho Shin, Kyung Hyun Oh, Young Ho Hong, Seog-Kyun Mun
OBJECTIVES: To evaluate the value of cervical vestibular evoked myogenic potential (cVEMP) as a prognostic factor for benign paroxysmal positional vertigo (BPPV). METHODS: We reviewed 65 patients with BPPV who underwent cVEMP. Patients were divided into two groups according to resistance to the repositioning maneuver. Univariable and multivariable analyses were performed with age, gender, affected semicircular canal, affected side and cVEMP parameters to find the associated factors for resistance to the repositioning maneuver...
December 18, 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28062802/moving-target-transient-rotational-stenosis-precipitating-jugular-bow-hunter-s-syndrome
#3
Waleed Brinjikji, Christopher S Graffeo, Avital Perry, Terence Zimmerman, Jeffrey R Janus, Pearce P Morris, Gregory D Cascino, Giuseppe Lanzino
A 60-year-old man presented with a 10-month history of of stereotypical spells characterized by vertigo, tinnitus, blurred vision, left hemibody numbness, and occasional syncope, precipitated by turning his head leftwards. Cerebral angiography and CT angiography of the head and neck with provocative maneuvers did not demonstrate vertebral artery narrowing. However, there was narrowing of the left internal jugular vein due to extrinsic compression from the sternocleidomastoid with leftward head rotation in the setting of hypoplasia of the right internal jugular vein...
January 6, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28055516/a-return-to-work-program-for-an-employee-with-resolving-vertigo
#4
Ann Regina Lurati
Vertigo is a disorder that affects equilibrium. Symptoms include a loss of balance with nausea and vomiting. Employees diagnosed with vertigo can return to work safely; however, they may need workplace restrictions and accommodation as symptoms may persist for months. This article reviews the evaluation and treatment of vertigo with back-to-work recommendations.
January 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28042454/exploratory-study-on-the-impact-of-switching-to-nilotinib-in-18-patients-with-chronic-myeloid-leukemia-in-chronic-phase-with-suboptimal-response-to-imatinib
#5
Sikander Ailawadhi, Luke P Akard, Carole B Miller, Anand Jillella, Daniel J DeAngelo, Solveig G Ericson, Felice Lin, Ghulam Warsi, Jerald Radich
BACKGROUND: The phase II, exploratory, open-label Exploring Nilotinib BCR-ABL Effects (ENABL) study [ClinicalTrials.gov identifier: NCT00644878] assessed the impact of switching to nilotinib therapy in patients with chronic myeloid leukemia in chronic phase (CML-CP) who had a suboptimal molecular response with imatinib. METHODS: Patients with CML-CP who had previously achieved a complete cytogenetic response (CCyR), but had a suboptimal molecular response, with frontline imatinib therapy (N = 18) were assigned to receive nilotinib 300 mg twice daily...
January 2017: Therapeutic Advances in Hematology
https://www.readbyqxmd.com/read/28033296/intratympanic-steroids-injection-is-effective-for-the-treatment-of-drop-attacks-with-m%C3%A3-ni%C3%A3-re-s-disease-and-delayed-endolymphatic-hydrops-a-retrospective-study
#6
Bo Liu, Yangming Leng, Renhong Zhou, Jingjing Liu, Dongdong Liu, Su-Lin Zhang, Wei-Jia Kong
Drop attack (DA) associated with Ménière's disease (MD) and delayed endolymphatic hydrops (DEH) is not common and may cause life-threatening clinical problems. The intratympanic dexamethasone (ITD) is one of primary treatments for MD or DEH. Our study investigated the effect of ITD on the DA associated with endolymphatic hydrops (EH).We retrospectively reviewed 10 patients with MD- and DEH-associated DA between January 2009 and December 2013 in Outpatient Department of Otolaryngology, Union Hospital, Wuhan, China...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28031157/evaluation-of-cervical-vestibular-evoked-myogenic-potential-findings-in-benign-paroxysmal-positional-vertigo
#7
Abdullah Karataş, Turgut Yüce, Işıl Taylan Çebi, Gülşah Acar Yüceant, Cemal Hacı, Mehti Salviz
OBJECTIVE: Although there has been a wide consensus on the mechanism of nystagmus and clinical presentation of benign paroxysmal positional vertigo (BPPV), the neuroepithelial pathophysiology of BPPV still remains unclear. In this study, we aimed to clarify the pathophysiology of BPPV by evaluating the cervical vestibular-evoked myogenic potential (cVEMP) findings of patients. MATERIALS AND METHODS: Thirty-six BPPV patients and 20 healthy volunteers were included...
December 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28031156/endolymphatic-duct-blockage-for-refractory-m%C3%A3-ni%C3%A3-re-s-disease-assessment-of-endolymphatic-sac-biopsy-on-short-term-surgical-outcomes
#8
Marc Henri Asmar, Issam Saliba
OBJECTIVE: Endolymphatic sac decompression (ESD) for the treatment of Ménière's disease (MD) has had limited success and variable results in the literature. We have devised a novel technique that involves blocking the endolymphatic duct with surgical clips. In a separate effort to study the endolymphatic sac (ELS), we have sectioned the lateral part of the main body of the ELS as biopsies from a subset of patients. We aimed to evaluate the effect of the lateral part sectioning of the ELS on short-term surgical outcomes...
December 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28031153/surgical-management-and-hearing-outcome-of-traumatic-ossicular-injuries
#9
Stefan Delrue, Nicolas Verhaert, Joost van Dinther, Andrzej Zarowski, Thomas Somers, Christian Desloovere, Erwin Offeciers
OBJECTIVE: The purpose of this study was to investigate etiological, clinical, and pathological characteristics of traumatic injuries of the middle ear ossicular chain and to evaluate hearing outcome after surgery. MATERIAL AND METHODS: Thirty consecutive patients (31 ears) with traumatic ossicular injuries operated on between 2004 and 2015 in two tertiary referral otologic centers were retrospectively analyzed. Traumatic events, clinical features, ossicular lesions, treatment procedures, and audiometric results were evaluated...
December 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28018691/intra-attack-vestibuloocular-reflex-changes-in-m%C3%A3-ni%C3%A3-re-s-disease
#10
Dario A Yacovino, John B Finlay
Ménière's attack has been shown to temporarily alter the vestibuloocular reflex (VOR). A patient with unilateral Ménière's disease was serially evaluated with the video Head Impulse Test during single, untreated episodes of acute vertigo. Spontaneous nystagmus activity was concurrently recorded in order to establish the three typical phases of Ménière's attack (irritative, paralytic, and recovery) and correlate them with VOR performance. The onset of attack was associated with a quick change in VOR gain on the side of the affected ear...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28008227/transbuccal-delivery-of-betahistine-dihydrochloride-from-mucoadhesive-tablets-with-a-unidirectional-drug-flow-in-vitro-ex-vivo-and-in-vivo-evaluation
#11
Mohamed A El-Nabarawi, Adel A Ali, Heba M Aboud, Amira H Hassan, Amany H Godah
OBJECTIVE: Betahistine dihydrochloride (BH.2HCl), an anti-vertigo histamine analog used in the treatment of Ménière's disease, undergoes extensive first-pass metabolism and suffers from short biological half-life. The aim of the present work was to develop and estimate controlled release mucoadhesive buccal tablets of BH.2HCl with a unidirectional drug flow to overcome this encumbrance. METHODS: A direct compression method was adopted for preparation of the tablets using mucoadhesive polymers like guar gum, hydroxypropyl methyl cellulose K4M, sodium carboxymethyl cellulose and their combinations...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27999539/an-overview-of-systematic-reviews-of-ginkgo-biloba-extracts-for-mild-cognitive-impairment-and-dementia
#12
REVIEW
Hong-Feng Zhang, Li-Bo Huang, Yan-Biao Zhong, Qi-Hui Zhou, Hui-Lin Wang, Guo-Qing Zheng, Yan Lin
Ginkgo biloba extracts (GBEs) have been recommended to improve cognitive function and to prevent cognitive decline, but earlier evidence was inconclusive. Here, we evaluated all systematic reviews of GBEs for prevention of cognitive decline, and intervention of mild cognitive impairment (MCI) and dementia. Six databases from their inception to September 2015 were searched. Ten systematic reviews were identified, including reviews about Alzheimer's disease (n = 3), about vascular dementia (n = 1), about both Alzheimer's disease and vascular dementia (n = 2), about Alzheimer's disease, vascular dementia and mixed dementia (n = 3), and a review about MCI (n = 1)...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27999126/moving-target-transient-rotational-stenosis-precipitating-jugular-bow-hunter-s-syndrome
#13
Waleed Brinjikji, Christopher S Graffeo, Avital Perry, Terence Zimmerman, Jeffrey R Janus, Pearce P Morris, Gregory D Cascino, Giuseppe Lanzino
A 60-year-old man presented with a 10-month history of of stereotypical spells characterized by vertigo, tinnitus, blurred vision, left hemibody numbness, and occasional syncope, precipitated by turning his head leftwards. Cerebral angiography and CT angiography of the head and neck with provocative maneuvers did not demonstrate vertebral artery narrowing. However, there was narrowing of the left internal jugular vein due to extrinsic compression from the sternocleidomastoid with leftward head rotation in the setting of hypoplasia of the right internal jugular vein...
December 20, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27974932/correlations-between-the-semiologic-changes-and-the-imaging-aspects-in-the-lateral-bulbar-infarction
#14
Cristea I, Popa C
The study aimed to evaluate the correlations between the clinical and paraclinical data in the lateral bulbar infarction, benefiting from the access to the semiologic characteristics of a group studied and the MRI angiography, without a contrast agent, through the 3D TOF technique combined with MIP, as an imaging technique for the evaluation of the arterial lesion. The study group included 20 patients with lateral bulbar infarction, 14 men, and 6 women aged between 21 and 80 years, the mean age being 56, 9 years, who were enrolled in the study in the period 2012 and 2014, following the admission in the National Institute of Neurology and Neurovascular Diseases...
July 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27942604/clinical-analysis-of-dizzy-patients-with-high-levels-of-depression-and-anxiety
#15
Sung Kyun Kim, Yong Bok Kim, Il-Seok Park, Seok Jin Hong, Heejin Kim, Seok Min Hong
BACKGROUND AND OBJECTIVES: Some patients experiencing dizziness also report psychological distress. However, the association between vestibular deficits and psychological symptoms remains controversial. Thus, the aim of this paper is to report the proportion of patients who complained of dizziness who also had high depression and anxiety indices. Also we investigated the severity of their dizziness and the distribution of the diseases underlying this symptom. SUBJECTS AND METHODS: We assessed the dizziness and psychological distress of 544 patients experiencing dizziness using the Korean versions of the Dizziness Handicap Inventory (DHI), the Beck Depression Inventory (BDI), and the Spielberger State-Trait Anxiety Inventory (STAI)...
December 2016: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/27934541/association-between-endothelial-dysfunction-and-otoneurological-symptoms-in-children-with-sickle-cell-disease
#16
Mara Renata Rissatto-Lago, Cristina Salles, Fernando Gesteira Campos de Pinho, Isa Menezes Lyra, Regina Terse-Ramos, Rozana Teixeira, Ana Marice Ladeia
OBJECTIVE: To evaluate the association between endothelial dysfunction and otoneurological symptoms and vaso-occlusive phenomena in children with sickle cell disease (SCD). METHODS: Cross-sectional study with 54 children, aged between 6 and19 years of age, of whom 28 had genotype SS and 26 apparently healthy (AA genotype) whose parents or guardians, or the children themselves, filled out a questionnaire designed to assess their otoneurological symptoms. All the individuals were submitted assessment of endothelial function by flow-mediated dilation (FMD) percentage with reactive hyperemia of brachial artery Doppler...
December 9, 2016: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/27929596/primary-solitary-intralabyrinthine-schwannoma-a-report-of-7-cases-and-a-review-of-the-literature
#17
Avi Shupak, Yehuda Holdstein, Margalit Kaminer, Itzhak Braverman
Intralabyrinthine schwannomas (ILSs) are uncommon benign tumors that originate in the Schwann cell sheath of the intralabyrinthine distal branches of the vestibulocochlear nerve. They have no initial involvement in the internal auditory canal, although that might develop later. These lesions can arise inside the cochlea, originate in the vestibule or, in rare cases, develop in the semicircular canals. From these sites, spread might take place via the anatomic connections between the perilymphatic spaces in the scala vestibuli and the anterior vestibule...
December 2016: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/27926585/fluctuating-vestibulo-ocular-reflex-in-m%C3%A3-ni%C3%A3-re-s-disease
#18
Dario A Yacovino, Timothy C Hain, Maria Musazzi
OBJECTIVES: To describe the fluctuating high velocity vestibular ocular-reflex (VOR) during the Ménière's attacks and correlate those features with pathophysiology. PATIENTS: A patient with unilateral Ménière's disease (MD) was evaluated closely during and after acute vertigo episodes. MAIN OUTCOME MEASURES: The spontaneous nystagmus and the dynamic VOR changes were measured by the video head impulse test (VHIT) at different stages of the vertigo crisis and during the quiescent phase of the condition...
December 6, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27918366/oculographic-clinical-test-of-sensory-integration-and-balance-and-computerized-dynamic-posturography-findings-in-patients-with-psoriatic-arthritis
#19
Juan Carlos Amor-Dorado, Maria P Barreira-Fernandez, Javier Llorca, Miguel A Gonzalez-Gay
OBJECTIVE: To assess the frequency and characteristics of the oculographic findings and the usefulness of the clinical test of sensory integration and balance (CTSIB) for the evaluation of balance in patients with psoriatic arthritis (PsA) by comparing this test with the computerized dynamic posturography (CDP). STUDY DESIGN: A series of consecutive patients that fulfilled the Moll and Wright criteria for PsA and matched controls were studied. SETTING: The study was performed at the Otolaryngology Division of a tertiary reference center...
December 1, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27917721/prognostic-factors-for-idiopathic-sudden-sensorineural-hearing-loss-treated-with-hyperbaric-oxygen-therapy-and-intravenous-steroids
#20
S Hosokawa, K Sugiyama, G Takahashi, S Takebayashi, H Mineta
OBJECTIVE: This study evaluated the prognosis of idiopathic sudden sensorineural hearing loss when treated with hyperbaric oxygen therapy and intravenous steroids. METHODS: The clinical data for 334 patients with idiopathic sudden sensorineural hearing loss treated by hyperbaric oxygen therapy and intravenous steroids at our hospital were retrospectively reviewed. These data included the initial averaged five-frequency hearing level, patient age, interval between onset of symptoms and treatment, vertigo as a complication, and co-existence of diabetes mellitus...
January 2017: Journal of Laryngology and Otology
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