John E Fleming, Moaad Benjaber, Robert Toth, Mayela Zamora, Kei Landin, Ali Kavoosi, Jonathan Ottoway, Tom Gillbe, Rory J Piper, Tara Noone, Hannah Campbell, Ivor Gillbe, Marios Kaliakatsos, Martin Tisdall, Antonio Valentin, Timothy Denison
Providing clinicians with objective outcomes of neuromodulation therapy is a key unmet need, especially in emerging areas such as epilepsy and mood disorders. These diseases have episodic behavior and circadian/multidien rhythm characteristics that are difficult to capture in short clinical follow-ups. This work presents preliminary validation evidence for an implantable neuromodulation system with integrated physiological event monitoring, with an initial focus on seizure tracking for epilepsy. The system was developed to address currently unmet requirements for patients undergoing neuromodulation therapy for neurological disorders, specifically the ability to sense physiological data during stimulation and track events with seconds-level granularity...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society