keyword
MENU ▼
Read by QxMD icon Read
search

blood lipid level

keyword
https://www.readbyqxmd.com/read/27933294/branched-chain-amino-acid-levels-are-related-with-surrogates-of-disturbed-lipid-metabolism-among-older-men
#1
Urho M Kujala, Markku Peltonen, Merja K Laine, Jaakko Kaprio, Olli J Heinonen, Jouko Sundvall, Johan G Eriksson, Antti Jula, Seppo Sarna, Heikki Kainulainen
AIMS/HYPOTHESIS: Existing studies suggest that decreased branched-chain amino acid (BCAA) catabolism and thus elevated levels in blood are associated with metabolic disturbances. Based on such information, we have developed a hypothesis how BCAA degradation mechanistically connects to tricarboxylic acid cycle, intramyocellular lipid storage, and oxidation, thus allowing more efficient mitochondrial energy production from lipids as well as providing better metabolic health. We analyzed whether data from aged Finnish men are in line with our mechanistic hypothesis linking BCAA catabolism and metabolic disturbances...
2016: Frontiers in Medicine
https://www.readbyqxmd.com/read/27932762/-correlations-between-lipid-ratio-oxidative-stress-status-in-copd-patients-and-pulmonary-hypertension-%C3%A2-as-well-as-prognosis
#2
Chunzhi Li, Li Yan, Jinwei Xu
To investigate the correlations between lipid ratio/oxidative stress status in chronic obstructive pulmonary disease (COPD) patients and pulmonary hypertension as well as the prognosis.
 Methods: A total of 120 patients with COPD were randomly selected and served as the COPD group and 30 healthy persons were selected as the control group. The ratios of low density lipoprotein (LDL)/high-density lipoprotein (HDL), triglyceride (TG)/HDL and total cholesterol (TC)/HDL were measured. The superoxide dismutase (SOD) activity, malondialdehyde (MDA) content and total antioxidant capacity (T-AOC) level in the control group and COPD patients were detected...
November 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27932336/heat-stress-hydration-and-uric-acid-a-cross-sectional-study-in-workers-of-three-occupations-in-a-hotspot-of-mesoamerican-nephropathy-in-nicaragua
#3
Catharina Wesseling, Aurora Aragón, Marvin González, Ilana Weiss, Jason Glaser, Christopher J Rivard, Carlos Roncal-Jiménez, Ricardo Correa-Rotter, Richard J Johnson
OBJECTIVES: To study Mesoamerican nephropathy (MeN) and its risk factors in three hot occupations. DESIGN: Cross-sectional. SETTING: Chinandega and León municipalities, a MeN hotspot on the Nicaraguan Pacific coast, January-February 2013. PARTICIPANTS: 194 male workers aged 17-39 years: 86 sugarcane cutters, 56 construction workers, 52 small-scale farmers. OUTCOME MEASURES: (1) Differences between the three occupational groups in prevalences/levels of socioeconomic, occupational, lifestyle and health risk factors for chronic kidney disease (CKD) and in biomarkers of kidney function and hydration; (2) differences in prevalences/levels of CKD risk factors between workers with reduced estimated glomerular filtration rate (eGFRCKD-EPI <80 mL/min/1...
December 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27931773/protective-effect-of-propofol-on-noise-induced-hearing-loss
#4
Jian Wen, Na Duan, Qiang Wang, Gui-Xia Jing, Ying Xiao
PURPOSE: Iatrogenic noise produced by mastoid or craniotomy drills may cause hearing damage, which is induced by the generation of reactive oxygen species (ROS) and the reduction of cochlear blood flow (CoBF). This study investigated whether propofol could reduce noise-induced hearing loss (NIHL) in a guinea pig model. METHODS: Sixty-four male pigmented guinea pigs were randomly and equally divided into 4 groups: control, noise, propofol and propofol+noise. Propofol was infused intravenously for 20 min prior to noise exposure with a loading dose of 5 mg·kg(-1) for 5 min and a maintenance infusion of 20 mg·kg(-1)·h(-1) for 135 min...
December 5, 2016: Brain Research
https://www.readbyqxmd.com/read/27930815/ctrp-3-is-permeable-to-the-blood-brain-barrier-and-is-not-regulated-by-glucose-or-lipids-in-vivo
#5
Andreas Schmid, Martin Berghoff, Alexandra Hochberg, Andreas Schäffler, Thomas Karrasch
C1q/TNF-related protein-3 (CTRP-3) represents a novel anti-inflammatory and anti-diabetic adipokine secreted by adipose tissue. The physiological and postprandial regulation of CTRP-3 remains obscure and it is not known whether CTRP-3 is permeable to the brain AIM: The postprandial regulation of CTRP-3 during an oral glucose tolerance test (n=100) and an oral lipid tolerance test (n=100) in humans was investigated. Moreover, CTRP-3 concentrations were measured in paired serum and cerebrospinal fluid (CSF) samples of patients (n=270) undergoing neurological evaluation...
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27930810/alamandine-abrogates-neutrophil-degranulation-in-atherosclerotic-mice
#6
Analina R Da Silva, Sébastien Lenglet, Federico Carbone, Fabienne Burger, Aline Roth, Luca Liberale, Aldo Bonaventura, Franco Dallegri, Nikolaos Stergiopulos, Robson A S Santos, François Mach, Rodrigo A Fraga-Silva, Fabrizio Montecucco
Neutrophil-mediated inflammation was recently identified as an active contributor to athero-progression. Therapeutic strategies inhibiting neutrophil degranulation or recruitment were hypothesized to positively impact on plaque vulnerability. In this study, we investigated whether treatment with the recently discovered agonist of the Mas-related G-coupled receptor type D (MrgD) alamandine would impact on neutrophil degranulation in vivo and in vitro MATERIALS AND METHODS: Fifteen-week old ApoE-/- mice were fed with a Western-type diet for an additional 11 weeks...
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27928525/effects-of-alcohol-consumption-frequency-on-health-index-in-korean-women
#7
Hee-Ju Kwon, Ik-Rae Cho, Hyo-Joo Park, Tae-Young Kim
BACKGROUND: In this study, we examined the status of Korean women's alcohol consumption and identified the physical changes they undergo according to the level of consumption. The results of this study may thus be used as raw data to effectively control women' drinking habits. METHODS: This study consists of a secondary analysis using data from female participants in the 6(th) Korea National Health and Nutrition Examination Survey, which was conducted by the Korea Centers for Disease Control and Prevention(2013-2014, V-2)...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27928227/baicalin-and-geniposide-inhibit-the-development-of-atherosclerosis-by-increasing-wnt1-and-inhibiting-dickkopf-related-protein-1-expression
#8
Bin Wang, Ping-Ping Liao, Li-Hua Liu, Xin Fang, Wei Li, Si-Ming Guan
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin and geniposide could inhibit atherosclerosis through Wnt1 and dickkopf-related protein-1 (DKK1). METHODS: The wild-type and ApoE(-/-) mice were treated with baicalin, geniposide, and baicalin plus geniposide daily by gavage for 12 weeks. Blood lipid levels were measured with an automatic biochemistry analyzer...
October 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27926952/growth-hormone-treatment-increases-plasma-irisin-concentration-in-patients-with-turner-syndrome
#9
B Wikiera, K Zawadzka, Ł Łaczmański, N Słoka, M Bolanowski, A Basiak, A Noczyńska, J Daroszewski
Irisin (Ir) deficiency may be a contributing factor in metabolic disease. This study aimed to investigate the effect of supraphysiological doses of recombinant human growth hormone (rhGH) on Ir plasma concentration in relation to metabolic disorders, including obesity and other components of metabolic syndrome. We studied 36 girls with Turner syndrome (mean age 8.2 years) treated with rhGH (0.05 mg/kg/day). Anthropometric data and fasting blood levels [e. g., Ir, insulin, glucose, glycated hemoglobin (HbA1c), IGF-1, IGFBP-3, cholesterol, insulin resistance (HOMA-IR), and β-cell function (HOMA-β)] were analyzed prior to and following rhGH therapy [mean (SD) follow-up of 1...
December 7, 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/27926460/association-of-serum-n-3-polyunsaturated-fatty-acids-with-psychological-distress-in-the-second-and-third-trimesters-of-pregnancy-adjunct-study-of-japan-environment-and-children-s-study
#10
Kei Hamazaki, Akiko Harauma, Satoru Tanabe, Miho Namai, Toru Moriguchi, Hidekuni Inadera
The results of several epidemiological studies and clinical trials investigating the effects of n-3 polyunsaturated fatty acids (PUFAs) on antenatal and postnatal depression remain controversial. In a previous case-control study of early pregnancy in Japan, we found an inverse association between eicosapentaenoic acid and risk of psychological distress after adjusting for possible confounders. Here, in a 1:2 matched case-control study, we further investigated the possible relationship between serum n-3 PUFAs and risk of psychological distress in the second and third trimesters of pregnancy...
November 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27923453/circulating-micrornas-as-biomarkers-for-metabolic-disease
#11
REVIEW
Marcelina Párrizas, Anna Novials
Incidence of diabetes and other metabolic disorders is increasing worldwide, with almost half the cases remaining undiagnosed. This is cause for concern as poor management of glucose or lipid levels causes tissue damage that may result in micro- or macrovascular complications. Current methods of diagnosing metabolic disorders do not provide any clues on disease aetiology or their posterior evolution and incidence of complications, which are the main cause of disease-associated morbidity. Circulating microRNAs found in blood change with the physiological condition of the organism and may help to: (1) identify people at risk of developing metabolic disease, (2) diagnose diabetes or other metabolic disorders on the basis of their aetiology, (3) predict the development of complications, and (4) monitor response to treatment...
October 2016: Best Practice & Research. Clinical Endocrinology & Metabolism
https://www.readbyqxmd.com/read/27923262/circulating-levels-of-lamp2-in-coronary-artery-disease-association-with-serum-lipid-profile
#12
M Teimouri, P Shabani, F Zali, M Najafi, H Shateri, M Asadnia, A Vatannejad, M Najafi, M Doosti
Whereas several in vitro and in vivo studies have described the role of lysosomal associated membrane protein 2 (LAMP2) in lipid homeostasis, there is no study addressing LAMP2 serum concentration and its association with lipid profiles in the context of coronary artery disease (CAD). We aimed to determine the LAMP2 serum concentration and its association with serum lipid profiles as well as the gene expression of LAMP2 in peripheral blood mononuclear cells (PBMCs) of CAD patients and control group. Circulating levels of LAMP2 were quantified by enzyme-linked immunosorbent assay (ELISA) in CAD patients (n=85) and control group (n=65) and correlation to lipid parameters was assessed...
December 6, 2016: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/27923158/effect-of-intensive-lipid-lowering-therapies-on-cholinesterase-activity-in-patients-with-coronary-artery-disease
#13
Edyta Pytel, Bożena Bukowska, Maria Koter-Michalak, Małgorzata Olszewska-Banaszczyk, Paulina Gorzelak-Pabiś, Marlena Broncel
BACKGROUND: Many disease entities, including coronary artery disease (CAD), demonstrate abnormalities in the activity of cholinesterases. As CAD is characterized by an increase in cholesterol level, patients with this disease are treated with lipid-lowering drugs. The present study attempts to determine how statin or combined statin and ezetimibe therapy influences cholinesterase activity. METHODS: Plasma and erythrocytes were isolated from the peripheral blood of CAD patients (n=61) and healthy subjects (n=63)...
September 21, 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/27922551/sphingosine-1-phosphate-s1p-a-potential-biomarker-and-therapeutic-target-for-endothelial-dysfunction-and-sepsis
#14
Martin S Winkler, Axel Nierhaus, Annika Poppe, Gillis Greiwe, Markus Gräler, Guenter Daum
Sepsis is an acute life-threatening multiple organ failure caused by a dysregulated host response to infection. Endothelial dysfunction, particularly barrier disruption leading to increased vascular permeability, edema and insufficient tissue oxygenation is critical to sepsis pathogenesis. Sphingosine-1-phosphate (S1P) is a signaling lipid that regulates important pathophysiological processes including vascular endothelial cell permeability, inflammation and coagulation. It is present at high concentrations in blood and lymph and at very low concentrations in tissues due to the activity of the S1P-degrading enzyme S1P-lyase in tissue cells...
December 2, 2016: Shock
https://www.readbyqxmd.com/read/27921357/interrelationship-between-mini-mental-state-examination-scores-and-biochemical-parameters-in-patients-with-mild-cognitive-impairment-and-alzheimer-s-disease
#15
Ramasamy Vasantharekha, Hannah P Priyanka, Thangavel Swarnalingam, Avathvadi Venkatesan Srinivasan, Srinivasan ThyagaRajan
AIM: The aim of the present study was to provide first-hand information about the prevalence of mild cognitive impairment (MCI) and Alzheimer's disease (AD) in Tamil Nadu, a southern state in India, and examine if there exists a relationship between cognitive functions and biochemical parameters in these patients. METHODS: Surveys were collected from adults, older men and women (n = 3126) from different regions of Tamil Nadu, which were followed up after 12 months for 1337 participants...
December 6, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27921196/danshen-injection-as-adjuvant-treatment-for-unstable-angina-pectoris-a-systematic-review-and-meta-analysis
#16
Jia-Rui Wu, Shi Liu, Xiao-Meng Zhang, Bing Zhang
OBJECTIVE: To systematically evaluate the clinical effectiveness and safety of Danshen Injection (, DS) as one adjuvant treatment for conventional therapy with Western medicine (WM) for unstable angina pectoris (UAP). METHODS: Using literature databases, a thorough and systematic retrieval of randomized controlled trials (RCTs) comparing DS plus WM with WM was conducted from inception to April 2015. The extracted data from included studies was analyzed by Review Manager 5...
December 5, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27921025/prostate-specific-antigen-rising-in-iranian-men-in-correlation-with-body-mass-index-fasting-blood-sugar-and-blood-lipid-profile
#17
Davood Arab, Arash Ardestani Zadeh, Majid Mirmohammadkhani, Azadeh Beiglarzadeh
BACKGROUND: Prostate-specific antigen (PSA) is a serine protease that is secreted by prostate cells and it is useful as a tumor marker for prostate cancer. OBJECTIVES: In this study, the relationship between some of metabolic factors and serum PSA level was investigated. MATERIALS AND METHODS: In this cross-sectional study, patients with urinary symptoms or for screening of the prostate cancer (after 50 years of age or 40 years with a family history of prostate cancer), were evaluated...
October 2016: Journal of Nephropathology
https://www.readbyqxmd.com/read/27920511/relationships-between-fto-rs9939609-mc4r-rs17782313-and-ppar%C3%AE-rs1801282-polymorphisms-and-the-occurrence-of-selected-metabolic-and-hormonal-disorders-in-middle-aged-and-elderly-men-a-preliminary-study
#18
Iwona Rotter, Karolina Skonieczna-Żydecka, Danuta Kosik-Bogacka, Grażyna Adler, Aleksandra Rył, Maria Laszczyńska
PURPOSE: Metabolic disorders, including MetS, obesity, and lipid disorders, may be related to genetic factors. Metabolic disorders are associated with decreased TS levels in aging men. The aim of this study was to evaluate the relationship between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the presence of MetS and its components, the concurrent lipid disorders, as well as sex hormone concentrations. SUBJECTS AND METHODS: This study involved 272 men of Caucasian descent aged 50-75 years...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27920412/leptin-and-calorie-intake-among-different-nicotine-dependent-groups
#19
Muhammad Zulhusni Suhaimi, Zulkefli Sanip, Hamid Jan Jan, Harmy Mohamed Yusoff
BACKGROUND: Exposure to nicotine via tobacco smoking may influence leptin release and decrease food intake among smokers. However, the effect of nicotine exposure on leptin and food intake among different nicotine dependent groups is unclear. OBJECTIVE: We aimed to measure leptin and calorie intake among different nicotine dependent groups. DESIGN: Cross-sectional study. SETTING: Research department in school of medical sciences...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27919543/maternal-plasma-polyunsaturated-fatty-acid-levels-during-pregnancy-and-childhood-lipid-and-insulin-levels
#20
A J Vidakovic, V W V Jaddoe, T Voortman, H Demmelmair, B Koletzko, R Gaillard
BACKGROUND AND AIMS: Maternal polyunsaturated fatty acid (PUFA) levels are associated with cord blood lipid and insulin levels. Not much is known about the influence of maternal PUFAs during pregnancy on long-term offspring lipid and insulin metabolism. We examined the associations of maternal plasma n-3 and n-6 PUFA levels during pregnancy with childhood lipid and insulin levels. METHODS AND RESULTS: In a population-based prospective cohort study, among 3230 mothers and their children, we measured maternal second trimester n-3 and n-6 PUFA plasma levels...
October 12, 2016: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
keyword
keyword
109700
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"