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https://www.readbyqxmd.com/read/27919020/psychosocial-factors-associated-with-migraine-and-tension-type-headache-in-medical-students
#1
Elena R Lebedeva, Natalia R Kobzeva, Denis V Gilev, Nadezhda V Kislyak, Jes Olesen
BACKGROUND: In our previous study of workers, blood donors and medical students, students stood out with a higher 1-year prevalence of migraine (28%) and tension-type headache (TTH) (74%). General factors associated with headache were common for all groups except low physical activity. The hypothesis of this study was therefore that a number of psychosocial factors relating to the personal sphere would better explain the high prevalence of migraine and TTH in students. METHODS: The study population consisted of 1042 students (719 females, 323 males, mean age 20...
November 8, 2016: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/27913001/cancer-related-fatigue-persistent-pervasive-and-problematic
#2
REVIEW
Lynn H Gerber
Cancer-related fatigue (CRF) is commonly reported by patients with cancer before, during, and after treatment. It is a persistent sense of tiredness that interferes with function, is distressing, and requires monitoring and, possibly, treatment. Fatigue assessment requires objective measures and self-reports, such as Functional Assessment of Cancer Therapy-Fatigue. Significant contributors to CRF include anemia, pain, insomnia, depressive symptoms, and elevated BMI. Elevated inflammatory cytokines, diabetes mellitus, cortisol, and cellular dysregulation have been associated with CRF...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27909987/orexin-ox2-receptor-antagonists-as-sleep-aids
#3
Laura H Jacobson, Sui Chen, Sanjida Mir, Daniel Hoyer
The discovery of the orexin system represents the single major progress in the sleep field of the last three to four decades. The two orexin peptides and their two receptors play a major role in arousal and sleep/wake cycles. Defects in the orexin system lead to narcolepsy with cataplexy in humans and dogs and can be experimentally reproduced in rodents. At least six orexin receptor antagonists have reached Phase II or Phase III clinical trials in insomnia, five of which are dual orexin receptor antagonists (DORAs) that target both OX1 and OX2 receptors (OX2Rs)...
December 2, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/27908913/comfrey-herbal-remedy-causing-second-degree-heart-block-do-not-be-outfoxed-by-digitalis
#4
Mathew Kurian Vithayathil, Matthew Edwards
A previously well woman aged 63 years presents to the emergency department with vomiting, palpitations and 3 presyncopal episodes. She had no previous medical or cardiac history, with the patient stating that she tried a herbal remedy of boiled comfrey leaves for insomnia 18 hours before arrival to the department. Her ECG showed multiple abnormalities, including bradycardia, second-degree atrioventricular node block, Mobitz Type 2, a shortened QT interval, downsloping ST depression and presence of U waves...
December 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27908262/sleep-alterations-in-non-demented-older-individuals-the-role-of-cortisol
#5
Ana Belén Castelló-Domenech, Vanessa Ibáñez Del Valle, Julio Fernández-Garrido, Mary Martínez-Martínez, Omar Cauli
BACKGROUND: Sleep alterations can impair quality of life and contribute to disease progression but they, and their features and contributing factors, are rarely analysed in institutionalised older individuals. In this study we investigated sleep alterations, the factors involved, and the role of cortisol in sleep-related problems in institutionalised individuals. METHODS: We conducted a descriptive cross-sectional study in participants living in nursing homes in Valencia (Spain); sleep alterations were determined based on two validated tools: the Athens insomnia scale and Oviedo sleep questionnaire...
November 30, 2016: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/27907210/assessing-potentially-inappropriate-prescribing-in-community-dwelling-older-patients-using-the-updated-version-of-stopp-start-criteria-a-comparison-of-profiles-and-prevalences-with-respect-to-the-original-version
#6
Encarnación Blanco-Reina, Maria Rosa García-Merino, Ricardo Ocaña-Riola, Lorena Aguilar-Cano, Jennifer Valdellós, Inmaculada Bellido-Estévez, Gabriel Ariza-Zafra
Emerging and changing evidence made it necessary to update STOPP-START criteria, and version 2 was published recently. In this study the objectives were to determine the prevalence of potentially inappropriate medication prescribing (PIM) in primary care using STOPP versions 1 (v1) and 2 (v2), as well as 2012 AGS Beers criteria, and analyze the factors associated with inappropriate prescribing according to STOPP/START v2. A cross-sectional study was carried out including community-dwelling older adults over the age of 65...
2016: PloS One
https://www.readbyqxmd.com/read/27904656/the-berlin-treatment-algorithm-recommendations-for-tailored-innovative-therapeutic-strategies-for-multiple-sclerosis-related-fatigue
#7
REVIEW
Christian Veauthier, Helge Hasselmann, Stefan M Gold, Friedemann Paul
More than 80% of multiple sclerosis (MS) patients suffer from fatigue. Despite this, there are few therapeutic options and evidence-based pharmacological treatments are lacking. The associated societal burden is substantial (MS fatigue is a major reason for part-time employment or early retirement), and at least one out of four MS patients view fatigue as the most burdensome symptom of their disease. The mechanisms underlying MS-related fatigue are poorly understood, and objective criteria for distinguishing and evaluating levels of fatigue and tiredness have not yet been developed...
2016: EPMA Journal
https://www.readbyqxmd.com/read/27902836/effect-of-a-web-based-cognitive-behavior-therapy-for-insomnia-intervention-with-1-year-follow-up-a-randomized-clinical-trial
#8
Lee M Ritterband, Frances P Thorndike, Karen S Ingersoll, Holly R Lord, Linda Gonder-Frederick, Christina Frederick, Mark S Quigg, Wendy F Cohn, Charles M Morin
Importance: Although cognitive behavior therapy for insomnia (CBT-I) has been established as the first-line recommendation for the millions of adults with chronic insomnia, there is a paucity of trained clinicians to deliver this much needed treatment. Internet-delivered CBT-I has shown promise as a method to overcome this obstacle; however, the long-term effectiveness has not been proven in a representative sample with chronic insomnia. Objective: To evaluate a web-based, automated CBT-I intervention to improve insomnia in the short term (9 weeks) and long term (1 year)...
November 30, 2016: JAMA Psychiatry
https://www.readbyqxmd.com/read/27900743/-the-relationship-between-coping-behaviors-and-symptom-distress-in-elderly-patients-with-cancer-undergoing-initial-chemotherapy
#9
Shih-Ping Wu, Ya-Chuan Hsu
BACKGROUND: Elderly cancer patients undergoing initial chemotherapy often suffer discomfort from medication-related symptom distress. This discomfort may affect treatment responses and outcomes negatively. PURPOSE: This correlational, cross-sectional design study used a purposive sample of 100 patients who were both over 60 years of age and currently undergoing initial chemotherapy. The participants completed a structured questionnaire that was administered at a medical center in southern Taiwan...
December 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27893672/risk-factors-of-severe-hypoglycemia-requiring-medical-assistance-and-neurological-sequelae-in-patients-with-diabetes-a-case-control-study
#10
Ja Young Jeon, Se Ran Kim, Hae Jin Kim, Dae Jung Kim, Kwan-Woo Lee, Jung-Dong Lee, Seung Jin Han
Hypoglycemia commonly occurs in patients who are being treated for diabetes. In some cases, these patients suffer from severe hypoglycemia that requires medical assistance and which can unfortunately result in long-term disabilities. Therefore, we investigated risk factors associated with severe hypoglycemia requiring medical assistance (HMA) and the resulting neurological sequelae in patients with diabetes. This investigation was a case-control study that assessed 129 patients with diabetes and documented hypoglycemia from a single tertiary hospital between February 2013 and May 2015...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27875034/risk-factors-of-post-traumatic-stress-symptoms-in-patients-with-cancer
#11
Yu-Hua Lin, Chia-Chan Kao, Shu-Fen Wu, Shu-Ling Hung, Hsing-Yu Yang, Hong-Yu Tung
AIM AND OBJECTIVES: To determine the level of PTSS and to identify demographics, disease history, and clinical symptoms that were associated with PTSS among gynecological, breast, or colorectal cancer patients in Taiwan. BACKGROUND: Literature indicated that 7.3 % to 35.2% of patients with cancer had experienced level of post-traumatic stress symptoms (PTSS). However, the PTSS among patients with cancer in Taiwan was not documented. DESIGN: A cross-sectional study...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27870551/poor-feeding-and-severe-sedation-in-a-newborn-nursed-by-a-mother-on-a-low-dose-of-amitriptyline
#12
Faruk Uguz
Sleep problems are frequently seen during the postpartum period. Some mothers need to use sedative agents for insomnia. Amitriptyline is a tricyclic antidepressant that has sedative effects. Despite no adverse reports, data on safety for the maternal use of this medication on breastfed infants are limited. This case report presents severe sedation and poor feeding in the breastfed baby of a woman using amitriptyline at 10 mg/day.
November 21, 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27863901/a-systematic-review-of-the-literature-on-disorders-of-sleep-and-wakefulness-in-parkinson-s-disease-from-2005-to-2015
#13
REVIEW
Lama M Chahine, Amy W Amara, Aleksandar Videnovic
Sleep disorders are among the most common non-motor manifestations in Parkinson's disease (PD) and have a significant negative impact on quality of life. While sleep disorders in PD share most characteristics with those that occur in the general population, there are several considerations specific to this patient population regarding diagnosis, management, and implications. The available research on these disorders is expanding rapidly, but many questions remain unanswered. We thus conducted a systematic review of the literature published from 2005 to 2015 on the following disorders of sleep and wakefulness in PD: REM sleep behavior disorder, insomnia, nocturia, restless legs syndrome and periodic limb movements, sleep disordered breathing, excessive daytime sleepiness, and circadian rhythm disorders...
August 31, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/27855756/a-population-based-study-on-nighttime-road-traffic-noiseand-insomnia
#14
Jorunn Evandt, Bente Oftedal, Norun Hjertager Krog, Per Nafstad, Per Schwarze, Gunn Marit Aasvang
STUDY OBJECTIVES: The aims of the present study were to investigate how nighttime road traffic noise relates to self-reported symptoms of insomnia and sleep medication use. METHODS: We used questionnaire data from the population-based study Health and Environment in Oslo (HELMILO) (2009-10) (N=13,019). The insomnia symptoms difficulties falling asleep, awakenings during the night and waking up too early in the morning, as well as self-reported sleep medication use were included as outcomes...
November 14, 2016: Sleep
https://www.readbyqxmd.com/read/27855734/pareidolias-in-effectiveness-of-benzodiazepine-receptor-agonists-in-the-treatment-of-insomnia-an-examination-of-response-and-remission-rates
#15
Vivek Pillai, Thomas Roth, Timothy Roehrs, Kenneth Moss, Edward L Peterson, Christopher L Drake
STUDY OBJECTIVES: To examine the real-world effectiveness of benzodiazepine receptor agonists (BzRAs) by quantifying response and remission rates in a clinical sample receiving chronic BzRA treatment for insomnia. METHODS: Participants were outpatients (N = 193; 72% female; 55.2 ± 11.1 yo) who had an insomnia diagnosis per medical records, and who were taking a therapeutic dose of BzRA for their insomnia. Endpoints were nocturnal sleep disturbance and Insomnia Severity Index (ISI) scores...
October 28, 2016: Sleep
https://www.readbyqxmd.com/read/27846774/insomnia-in-female-nurses-a-nationwide-retrospective-study
#16
Kasumi Tsai, Tzu-Yin Lee, Min-Huey Chung
OBJECTIVE: This study explored the incidence of insomnia in female nursing staff and compared the incidence with that in other medical and nonmedical female workers. METHODS: This retrospective study analyzed female nurses with insomnia using data from January 1, 2004 to December 31, 2008. The incidence of insomnia in other female medical workers and nonmedical female workers was also analyzed and compared with that of the nurses. Using the Taiwan National Health Insurance Research Database, each study patient was identified by ID number...
November 16, 2016: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/27846729/the-effects-of-age-and-gender-on-the-prevalence-of-insomnia-in-a-sample-of-the-saudi-population
#17
Anwar E Ahmed, Hamdan Al-Jahdali, Abdulhamid Fatani, Khalid Al-Rouqi, Fares Al-Jahdali, Abdullah Al-Harbi, Salim Baharoon, Yosra Z Ali, Mohammad Khan, Ahmad Rumayyan
OBJECTIVES: The aim of this study was to determine the prevalence of insomnia among the Saudi adult population. STUDY DESIGN: A cross-sectional insomnia survey was conducted at King Abdulaziz Medical City (KAMC) in Riyadh, Saudi Arabia. The presence of insomnia was defined by difficulty initiating sleep, early morning awakening, or frequent awakening, in addition to the second-day effect in the form of fatigue, tiredness, or changes in the mode because of lack of sleep...
November 16, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27825412/restless-legs-syndrome-in-adults-in-peking-union-medical-college-hospital
#18
Jian-Hua Chen, Rong Huang, Jin-Mei Luo, Yi Xiao, Xu Zhong, Xiu-Qin Liu
Objective To investigate the clinical characteristics of restless legs syndrome (RLS) in adults in Peking Union Medical College Hospital and explore the sleep quality,fatigue degree,daytime sleepiness,disease severity,depression and anxiety of RLS patients.Methods Totally 4739 consecutive patients who visited the outpatient departments with any sleep complaint or leg discomforts were recruited in the study. Patients under 18 years were excluded. All participants answered RLS questionnaire. The subjects fulfilled all four criteria would be followed up and given advanced examinations to rule out secondary RLS and RLS mimics...
October 10, 2016: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/27823719/individual-and-socio-demographic-factors-related-to-presenting-problem-and-diagnostic-impressions-at-a-pediatric-sleep-clinic
#19
Sonia L Rubens, Kristina E Patrick, Ariel A Williamson, Melisa Moore, Jodi A Mindell
OBJECTIVE: Individual and socio-demographic factors have been found to be associated with sleep disturbances in children. Few studies have examined these factors among children presenting for care at pediatric sleep clinics. This study examined individual and socio-demographic factors in association with presenting problems and diagnostic impressions for new patients at an interdisciplinary pediatric sleep clinic. METHODS: Data were collected from electronic medical records of 207 consecutive patients (54% male, 59% White, Meanage = 7...
September 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27823713/insomnia-among-current-and-remitted-common-mental-disorders-and-the-association-with-role-functioning-results-from-a-general-population-study
#20
Margreet Ten Have, Brenda W J H Penninx, Saskia van Dorsselaer, Marlous Tuithof, Marloes Kleinjan, Ron de Graaf
OBJECTIVE AND BACKGROUND: Insomnia is a neglected topic in psychiatric epidemiological studies. Despite the fact that insomnia is a common phenomenon and usually co-occurs with mental disorders, it remains to be addressed to what extent insomnia is associated with remitted and current common mental disorders and with impaired functioning in the population, after considering a wide variety of confounders. PATIENTS AND METHODS: Data were used from three waves of the Netherlands Mental Health Survey and Incidence Study-2 (N = 4618), a nationally representative face-to-face survey of the general population...
September 2016: Sleep Medicine
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