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https://www.readbyqxmd.com/read/27913931/prognostic-value-of-tumor-infiltrating-lymphocyte-subsets-in-breast-cancer-depends-on-hormone-receptor-status
#1
Yul Ri Chung, Hyun Jeong Kim, Min Hye Jang, So Yeon Park
PURPOSE: Interaction between immune-regulatory proteins and tumor infiltrating lymphocytes (TILs) is complex, and their associations may have significant clinical implications. This study was designed to evaluate the relationships between immunomodulatory proteins and TIL subsets and their impact on prognosis in breast cancer. METHODS: 377 invasive breast cancer cases were selected, and immunohistochemistry was performed for HLA-A, HLA-ABC, and indoleamine 2,3-dioxygenase (IDO); CD4+, CD8+, and FOXP3+ T cells were counted in intratumoral and stromal areas for both absolute numbers as well as their ratios...
December 2, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27907176/correction-potential-application-of-the-oryza-sativa-monodehydroascorbate-reductase-gene-osmdhar-to-improve-the-stress-tolerance-and-fermentative-capacity-of-saccharomyces-cerevisiae
#2
Il-Sup Kim, Young-Saeng Kim, Yul-Ho Kim, Ae Kyung Park, Han-Woo Kim, Jun-Hyuck Lee, Ho-Sung Yoon
[This corrects the article DOI: 10.1371/journal.pone.0158841.].
2016: PloS One
https://www.readbyqxmd.com/read/27904731/clinical-usefulness-of-long-term-application-of-fentanyl-matrix-in-chronic-non-cancer-pain-improvement-of-pain-and-physical-and-emotional-functions
#3
Jaewon Lee, Joon Shik Yoon, Jae Hyup Lee, So-Hak Chung, Kyu-Yeol Lee, Young Yul Kim, Jong Moon Kim, Min Ho Kong, Ung Gu Kang, Ye-Soo Park
BACKGROUND: Opioids are recently recommended for those who do not gain adequate pain relief from the use of acetaminophen or nonsteroidal anti-inflammatory drugs. Medical opioids are administered in various routes, and transdermal opioid products that can make up for the weaknesses of the oral or intravenous products have been developed. This study is to evaluate the clinical usefulness of fentanyl matrix in terms of the long-term improvement in pain and physical and mental functions...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27901174/metrics-for-electronic-nursing-record-based-narratives-cross-sectional-analysis
#4
Kidong Kim, Suyeon Jeong, Kyogu Lee, Hyeoun-Ae Park, Yul Ha Min, Joo Yun Lee, Yekyung Kim, Sooyoung Yoo, Gippeum Doh, Soyeon Ahn
OBJECTIVES: We aimed to determine the characteristics of quantitative metrics for nursing narratives documented in electronic nursing records and their association with hospital admission traits and diagnoses in a large data set not limited to specific patient events or hypotheses. METHODS: We collected 135,406,873 electronic, structured coded nursing narratives from 231,494 hospital admissions of patients discharged between 2008 and 2012 at a tertiary teaching institution that routinely uses an electronic health records system...
November 30, 2016: Applied Clinical Informatics
https://www.readbyqxmd.com/read/27871706/retrospective-study-of-maxillary-sinus-dimensions-and-pneumatization-in-adult-patients-with-an%C3%A2-anterior-open-bite
#5
Jesung Ryu, Sung-Hwan Choi, Jung-Yul Cha, Kee-Joon Lee, Chung-Ju Hwang
INTRODUCTION: The aim of this study was to evaluate differences in the maxillary sinus floor levels between adults with an anterior open bite and those without. METHODS: This retrospective study included 30 subjects: 15 adults with an anterior open bite (mean age, 21.5 ± 4.3 years) and 15 control subjects with normal occlusion (mean age, 21.7 ± 3.1 years). Cone-beam computed tomography and lateral cephalograms were analyzed before treatment. RESULTS: The open-bite group exhibited a significantly greater maxillary posterior alveolar height (P <0...
November 2016: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/27867928/world-health-organization-grade-ii-oligodendroglioma-occurring-after-successful-treatment-for-childhood-acute-lymphoblastic-leukemia
#6
Sang-In Yoon, Kyung-Jae Park, Dong-Hyuk Park, Shin-Hyuk Kang, Jung-Yul Park, Yong-Gu Chung
When treating childhood acute lymphoblastic leukemia (ALL), secondary neoplasms are a significant long term problem. Radiation is generally accepted to be a major cause of the development of secondary neoplasms. Following treatment for ALL, a variety of secondary tumors, including brain tumors, hematologic malignancies, sarcomas, thyroid cancers, and skin cancers have been reported. However, oligodendroglioma as a secondary neoplasm is extremely rare. Herein we present a case of secondary oligodendroglioma occurring 13 years after the end of ALL treatment...
October 2016: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/27861567/age-related-cataract-is-associated-with-elevated-serum-immunoglobulin-e-levels-in-the-south-korean-population-a-cross-sectional-study
#7
Tae Keun Yoo, Sun Woong Kim, Kyoung Yul Seo
BACKGROUND: Previous research has suggested that immunoglobulin E (IgE)-mediated events lead to several chronic diseases. We investigated the association between allergic conditions and age-related cataracts in the South Korean adult population. METHODS: A cross-sectional study was performed using data obtained from 1,170 participants aged 40 years or older who were enrolled in the Korean National Health and Nutrition Examination Survey 2010. Multivariable logistic regression was used to examine the relationship between age-related cataracts and allergic conditions, including total serum IgE and allergen-specific serum IgE levels, after adjustment for potential confounders (age, sex, alcohol consumption, smoking, sun exposure, blood pressure, plasma glucose and cholesterol levels, as well as histories of asthma, atopic dermatitis, and rheumatoid arthritis)...
2016: PloS One
https://www.readbyqxmd.com/read/27852939/sea-ice-rain-on-snow-and-tundra-reindeer-nomadism-in-arctic-russia
#8
Bruce C Forbes, Timo Kumpula, Nina Meschtyb, Roza Laptander, Marc Macias-Fauria, Pentti Zetterberg, Mariana Verdonen, Anna Skarin, Kwang-Yul Kim, Linette N Boisvert, Julienne C Stroeve, Annett Bartsch
Sea ice loss is accelerating in the Barents and Kara Seas (BKS). Assessing potential linkages between sea ice retreat/thinning and the region's ancient and unique social-ecological systems is a pressing task. Tundra nomadism remains a vitally important livelihood for indigenous Nenets and their large reindeer herds. Warming summer air temperatures have been linked to more frequent and sustained summer high-pressure systems over West Siberia, Russia, but not to sea ice retreat. At the same time, autumn/winter rain-on-snow (ROS) events have become more frequent and intense...
November 2016: Biology Letters
https://www.readbyqxmd.com/read/27836546/apbb1-reinforces-cancer-stem-cell-and-epithelial-to-mesenchymal-transition-by-regulating-the-igf1r-signaling-pathway-in-non-small-cell-lung-cancer-cells
#9
Jei Ha Lee, Jung Yul Kim, Seo Yeon Kim, Soo Im Choi, Kuk Chan Kim, Eun Wie Cho, In Gyu Kim
Amyloid β precursor protein binding family B member 1(APBB1) was first identified as a binding partner of amyloid precursor protein during brain development, but its function in the context of cancer remain unclear. Here we show for the first time that APBB1 is partly associated with intensifying cancer stem cell(CSC) and epithelial-to-mesenchymal transition (EMT) and enhancing radiation-resistant properties of lung cancer cells. We found that APBB1 was highly expressed in ALDH1(high) CSC-like cells sorted from A549 lung cancer cells...
November 9, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27834403/erratum-map-based-cloning-and-characterization-of-the-bph18-gene-from-wild-rice-conferring-resistance-to-brown-planthopper-bph-insect-pest
#10
Hyeonso Ji, Sung-Ryul Kim, Yul-Ho Kim, Jung-Pil Suh, Hyang-Mi Park, Nese Sreenivasulu, Gopal Misra, Suk-Man Kim, Sherry Lou Hechanova, Hakbum Kim, Gang-Seob Lee, Ung-Han Yoon, Tae-Ho Kim, Hyemin Lim, Suk-Chul Suh, Jungil Yang, Gynheung An, Kshirod K Jena
No abstract text is available yet for this article.
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27834351/corrigendum-time-dependent-effects-of-ultraviolet-and-nonthermal-atmospheric-pressure-plasma-on-the-biological-activity-of-titanium
#11
Sung-Hwan Choi, Won-Seok Jeong, Jung-Yul Cha, Jae-Hoon Lee, Hyung-Seog Yu, Eun-Ha Choi, Kwang-Mahn Kim, Chung-Ju Hwang
No abstract text is available yet for this article.
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27803041/association-between-duration-of-dual-antiplatelet-therapy-and-angiographic-multivessel-disease-on-outcomes-in-patients-treated-with-newer-generation-drug-eluting-stents
#12
Seung-Yul Lee, Myeong-Ki Hong, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Hyo-Soo Kim, Marco Valgimigli, Antonio Colombo, Martine Gilard, Tullio Palmerini, Gregg W Stone
BACKGROUND: There is general agreement that the optimal duration of dual antiplatelet therapy (DAPT) in patients treated with drug-eluting stents should be individualized. We hypothesized that the extent of coronary artery disease may affect the clinical outcomes of DAPT. METHODS AND RESULTS: We pooled patient-level data from 5 large, randomized trials comparing short-term DAPT with prolonged therapy. From the data, we identified 5476 patients who received newer-generation drug-eluting stents...
November 2016: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27793102/resequencing-of-capsicum-annuum-parental-lines-ycm334-and-taean-for-the-genetic-analysis-of-bacterial-wilt-resistance
#13
Yang Jae Kang, Yul-Kyun Ahn, Ki-Taek Kim, Tae-Hwan Jun
BACKGROUND: Bacterial wilt (BW) is a widespread plant disease that affects a broad range of dicot and monocot hosts and is particularly harmful for solanaceous plants, such as pepper, tomato, and eggplant. The pathogen responsible for BW is the soil-borne bacterium, Ralstonia solanacearum, which can adapt to diverse temperature conditions and is found in climates ranging from tropical to temperate. Resistance to BW has been detected in some pepper plant lines; however, the genomic loci and alleles that mediate this are poorly studied in this species...
October 28, 2016: BMC Plant Biology
https://www.readbyqxmd.com/read/27789170/intravascular-ultrasound-predictors-of-major-adverse-cardiovascular-events-after-implantation-of-everolimus-eluting-stents-for-long-coronary-lesions
#14
Seung-Yul Lee, Dong-Ho Shin, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
INTRODUCTION AND OBJECTIVES: There are limited data on the usefulness of intravascular ultrasound (IVUS) for long coronary lesions treated with second-generation drug-eluting stents. We evaluated IVUS predictors of major adverse cardiovascular events (MACE) 12 months after implantation of everolimus-eluting stents for long coronary lesions. METHODS: A total of 804 patients who underwent both postintervention IVUS examination and long everolimus-eluting stent (≥ 28mm in length) implantation were included from 2 randomized trials...
October 24, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27785555/clinical-and-radiologic-outcomes-of-arthroscopic-suture-bridge-repair-for-the-greater-tuberosity-fractures-of-the-proximal-humerus
#15
Jong-Hun Ji, Jae-Jung Jeong, Young-Yul Kim, Se-Won Lee, Do-Yeol Kim, Sang-Eun Park
PURPOSE: To report the clinical and radiological outcomes of arthroscopic suture bridge repair for the GT fractures of the shoulder joint. METHODS: From March 2008 to July 2013, we performed arthroscopic suture bridge repair of the GT fractures displaced more than 5 mm superiorly or posteriorly, but less than 2 cm in 40 cases [20 men, 20 women; mean age, 56 (27-80) years] with the average 32 (24-48) months follow-up. At the final follow-up, clinical (ASES, UCLA, SST, KSS score and range of motions) and radiological outcomes using post-operative MRI or CT scan were evaluated...
October 26, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27775893/5l-scale-magnesio-milling-reduction-of-nanostructured-sio2-for-high-capacity-silicon-anodes-in-lithium-ion-batteries
#16
Wonchul Cho, Hye Jin Kim, Hae In Lee, Myung Won Seo, Ho Won Ra, Sang Jun Yoon, Tae-Young Mun, Yong Ku Kim, Jae Ho Kim, Bo Hwa Kim, Jin Woo Kook, Chung-Yul Yoo, Jae Goo Lee, Jang Wook Choi
Nanostructured silicon (Si) is useful in many applications, and has typically been synthesized by bottom-up colloid-based solution processes or top-down gas phase reactions at high temperatures. These methods, however, suffer from toxic precursors, low yields, and impractical processing conditions (i.e., high pressure). The magnesiothermic reduction of silicon oxide (SiO2) has also been introduced as an alternative method. Here, we demonstrate the reduction of SiO2 by a simple milling process using a lab-scale planetary-ball mill and industry-scale attrition-mill...
October 24, 2016: Nano Letters
https://www.readbyqxmd.com/read/27768390/unpredictability-of-soft-tissue-changes-after-camouflage-treatment-of-class-ii-division-1-malocclusion-with-maximum-anterior-retraction-using-miniscrews
#17
Kayoung Kim, Sung-Hwan Choi, Eun-Hee Choi, Yoon-Jeong Choi, Chung-Ju Hwang, Jung-Yul Cha
OBJECTIVE: To compare soft and hard tissue responses based on the degree of maxillary incisor retraction using maximum anchorage in patients with Class II Division 1 malocclusion. MATERIALS AND METHODS: This retrospective study sample was divided into moderate retraction (<8.0 mm; n = 28) and maximum retraction (≥8.0 mm; n = 29) groups based on the amount of maxillary incisor retraction after extraction of the maxillary and mandibular first premolars for camouflage treatment...
September 19, 2016: Angle Orthodontist
https://www.readbyqxmd.com/read/27765503/valgus-extension-overload-syndrome-in-adolescent-baseball-players-clinical-characteristics-and-surgical-outcomes
#18
Jin-Young Park, Hyun-Yul Yoo, Seok Won Chung, Seung-Jun Lee, Na Ra Kim, Se-Young Ki, Kyung-Soo Oh
BACKGROUND: Little is known about the clinical characteristics and surgical outcomes of valgus extension overload syndrome (VEOS) in adolescent athletes. We evaluated posteromedial compartment pathology, including combined lesions, and reported the surgical outcomes in adolescent baseball players. METHODS: We retrospectively reviewed the medical records of 13 male adolescent baseball players (mean age, 15.4 years) who underwent arthroscopic olecranon tip resection (n = 9) or staged operations (arthroscopic olecranon tip resection, followed by medial collateral ligament reconstruction 2 weeks later; n = 4)...
December 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/27757136/the-relationship-between-personality-sense-of-efficacy-and-stress-in-korean-teachers
#19
Subin Park, Yul-Mai Song, Guy-Nueo Ko, Kyungun Jhung, Kyooseob Ha, Young-Ryeol Lee, Yeni Kim
Several studies have linked teachers' personality characteristics and sense of efficacy to stress. However, investigating the relationship between these three constructs in this context was limited. This study aims to investigate the relationship between personality, sense of efficacy and perceived stress among Korean teachers. A total of 137 teachers working in elementary, middle, and high schools located in Seoul, South Korea were recruited for the study. The participants were administered Temperament and Character Inventory, Teacher's Sense of Efficacy Scale (TSES), and Perceived Stress Scale...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27752121/osterix-represses-adipogenesis-by-negatively-regulating-ppar%C3%AE-transcriptional-activity
#20
Younho Han, Chae Yul Kim, Heesun Cheong, Kwang Youl Lee
Osterix is a novel bone-related transcription factor involved in osteoblast differentiation, and bone maturation. Because a reciprocal relationship exists between adipocyte and osteoblast differentiation of bone marrow derived mesenchymal stem cells, we hypothesized that Osterix might have a role in adipogenesis. Ablation of Osterix enhanced adipogenesis in 3T3-L1 cells, whereas overexpression suppressed this process and inhibited the expression of adipogenic markers including CCAAT/enhancer-binding protein alpha (C/EBPα) and peroxisome proliferator-activated receptor gamma (PPARγ)...
October 18, 2016: Scientific Reports
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