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https://www.readbyqxmd.com/read/28088398/mindfulness-based-stress-reduction-for-adolescents-with-functional-somatic-syndromes-a-pilot-cohort-study
#1
Ather Ali, Theresa R Weiss, Anne Dutton, Douglas McKee, Kim D Jones, Susmita Kashikar-Zuck, Wendy K Silverman, Eugene D Shapiro
OBJECTIVE: To assess the feasibility of a mindfulness-based stress reduction (MBSR) program for adolescents with widespread chronic pain and other functional somatic symptoms and to make preliminary assessments of its clinical utility. STUDY DESIGN: Three cohorts of subjects completed an 8-week MBSR program. Child- and parent-completed measures were collected at baseline and 8 and 12 weeks later. Measures included the Functional Disability Inventory (FDI), the Fibromyalgia/Symptom Impact Questionnaire-Revised (FIQR/SIQR), the Pediatric Quality of Life Inventory, the Multidimensional Anxiety Scale (MASC2), and the Perceived Stress Scale...
January 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28028189/implementation-of-a-%C3%AE-agonist-airway-clearance-protocol-in-a-pediatric-icu
#2
Gary R Lowe, J Randy Willis, Shasha Bai, Mark J Heulitt
BACKGROUND: Respiratory therapist (RT)-driven protocols have been in use for over 30 years. Protocols have been reported to decrease unnecessary or harmful therapy, health-care costs, and hospital stay. This study represents the evaluation of an original respiratory care protocol in the pediatric ICU at Arkansas Children's Hospital for β-agonist and airway clearance interventions where one did not exist. METHODS: This project was composed of 2 parts: a survey administered to RTs and licensed independent practitioners and a retrospective review of outcome data comparing a therapist-driven β-agonist/airway clearance protocol with physician-directed respiratory care ordering in a patient population admitted for acute respiratory failure...
December 27, 2016: Respiratory Care
https://www.readbyqxmd.com/read/28017963/the-impacts-of-the-interaction-of-genetic-variation-cyp11%C3%AE-2-and-nedd4l-with-sodium-intake-on-pediatric-obesity-with-gender-difference-a-three-year-panel-study
#3
M Lee, D Y Kwon, J Park
Backgrounds/ObjectivesThis panel study was to predict the incidences of pediatric obesity by the interaction of sodium (Na) intake and 9 SNPs of salt-sensitive genes (SSGs), ACE, ADD1 G460W, AGT M235T, CYP11β2, GNB3 C285T, GRK4 A142V, GRK4 A486V, NEDD4L and SLC12A3, selected from GWAS.Subjects/MethodsNon-obese (non-OB) Korean children of 9 years old were recruited from eight elementary schools in Seoul in 2007 and 2009, each. Follow-up subjects (total=798) in 2010 and 2012 were final participants. Participants were classified as obese group (OB) for those whose BMI were over the 85th percentile using the 'Korean National Growth Charts', and others were classified as non-OB...
December 26, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28011445/drivers-and-barriers-to-acceptance-of-web-based-aftercare-of-patients-in-inpatient-routine-care-a-cross-sectional-survey
#4
Severin Hennemann, Manfred E Beutel, Rüdiger Zwerenz
BACKGROUND: Web-based aftercare can help to stabilize treatment effects and support transition after inpatient treatment, yet uptake by patients seems limited in routine care and little is known about the mechanisms of adoption and implementation. OBJECTIVE: The aim of this study was to (1) determine acceptance of Web-based aftercare and (2) explore its drivers and barriers in different subgroups of a mixed inpatient sample. METHOD: In a cross-sectional design, 38...
December 23, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27924146/mindfulness-based-intervention-for-female-adolescents-with-chronic-pain-a-pilot-randomized-trial
#5
Nicholas Chadi, Audrey McMahon, Majorie Vadnais, Catherine Malboeuf-Hurtubise, Anissa Djemli, Patricia L Dobkin, Jacques Lacroix, Thuy Mai Luu, Nancy Haley
OBJECTIVE: To test the feasibility of a randomized-controlled trial measuring the impact of an adapted mindfulness-based intervention (MBI) in female adolescents with chronic pain. METHODS: This was a single center, single-blind, prospective, experimental, longitudinal trial conducted in a pediatric tertiary care center. Participants had a history of chronic pain during at least three months. They were randomized into an intervention group or a wait-list control group...
2016: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27919346/disease-control-via-intensified-lipoprotein-apheresis-in-three-siblings-with-familial-hypercholesterolemia
#6
Christina Taylan, Andrea Schlune, Thomas Meissner, Karolis Ažukaitis, Floris E A Udink Ten Cate, Lutz T Weber
BACKGROUND: Familial hypercholesterolemia (FH), the prevalent monogenic form of hypercholesterolemia, carries the risk of premature coronary heart disease. Lipoprotein-apheresis is established in children with severe dyslipidemia. We present 3 siblings with a negative/negative residual low-density lipoprotein (LDL) receptor mutation (p.Trp577Arg), unresponsive to drug treatment. OBJECTIVE: Intensified lipoprotein-apheresis is well tolerated and results in permanently low lipid values without harming the health-related quality of life in children...
November 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27773937/effect-of-phentermine-on-weight-reduction-in-a-pediatric-weight-management-clinic
#7
J R Ryder, A Kaizer, K D Rudser, A Gross, A S Kelly, C K Fox
Phentermine is the most widely prescribed obesity medication in adults, yet studies of its use in the pediatric population are limited. We conducted a retrospective chart review of adolescents with obesity treated in a pediatric weight management clinic to examine the weight loss effectiveness of phentermine added to standard of care (SOC) lifestyle modification therapy versus SOC alone. All patients receiving phentermine plus SOC (n=25) were matched with a comparison group receiving only SOC (n=274). Differences at 1, 3 and 6 months were evaluated using generalized estimated equations adjusting for age, sex and baseline body mass index (BMI) and robust variance standard error estimates for confidence intervals and P-values...
January 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27706462/effectiveness-of-prophylactic-non-invasive-ventilation-on-respiratory-function-in-the-postoperative-phase-of-pediatric-cardiac-surgery-a-randomized-controlled-trial
#8
Camilla R S Silva, Lívia B Andrade, Danielle A S X Maux, Andreza L Bezerra, Maria C M B Duarte
Objective: To evaluate the effectiveness of prophylactic, non-invasive ventilation (NIV) on respiratory function in seven- to 16-year-old children in the post-operative phase of cardiac surgery. Method: A randomized, controlled trial with 50 children who had undergone cardiac surgery with median sternotomy. After extubation, patients were randomly assigned to one of two groups: control group (n=26), which received instructions regarding posture, early ambulation, and cough stimulation, and CPAP group (continuous positive airway pressure; n=24), which received the same instructions as the control group and CPAP=10 cmH20 twice daily for 30 minutes from the 1st to the 5th post-operative day (POD)...
November 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27685196/two-year-follow-up-of-outcomes-related-to-scarring-and-distress-in-children-with-severe-burns
#9
Paul Wurzer, Abigail A Forbes, Gabriel Hundeshagen, Clark R Andersen, Kathryn M Epperson, Walter J Meyer, Lars P Kamolz, Ludwik K Branski, Oscar E Suman, David N Herndon, Celeste C Finnerty
PURPOSE: We assessed the perception of scarring and distress by pediatric burn survivors with burns covering more than one-third of total body surface area (TBSA) for up to 2 years post-burn. METHODS: Children with severe burns were admitted to our hospital between 2004 and 2012, and consented to this IRB-approved-study. Subjects completed at least one Scars Problems and/or Distress questionnaire between discharge and 24 months post burn. Outcomes were modeled with generalized estimating equations or using mixed linear models...
August 16, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27684849/elastic-stable-intramedullary-nailing-for-severely-displaced-distal-tibial-fractures-in-children
#10
Kaiying Shen, Haiqing Cai, Zhigang Wang, Yunlan Xu
Elastic stable intramedullary nailing (ESIN) has became a well-accepted method of osteosynthesis of diaphyseal fractures in the skeletally immature patient for many advantages, the purpose of this study is to evaluate the preliminary results of this minimally invasive treatment for severely displaced distal tibial diaphyseal metaphyseal junction (DTDMJ) fractures.This study was carried out over a 6-year period. Twenty-one severely displaced DTDMJ fractures treated using ESIN were evaluated clinically and radiographically...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27602915/cost-analysis-and-performance-in-distal-pediatric-forearm-fractures-is-a-short-arm-cast-superior-to-a-sugar-tong-splint
#11
Joshua S Acree, John Schlechter, Scott Buzin
The aim of this study is to compare splint versus cast immobilization for maintaining alignment following closed reduction of distal 1/3 radius and both-bone forearm fractures. We performed a retrospective review of patient records between 5 and 14 years old with a distal 1/3 radius or radius and ulna fracture requiring reduction. A cost comparison was also performed using facility costs for materials. Reduction was maintained with acceptable alignment in most cases (94%). Although a sugar-tong splint slightly maintained fracture alignment better, this was not significant...
September 3, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27513224/ct-radiation-dose-reduction-in-robot-assisted-pediatric-spinal-surgery
#12
William F Sensakovic, Matthew Cody O'Dell, Ali Agha, Raymund Woo, Laura Varich
STUDY DESIGN: Retrospective Consecutive Cohort Series OBJECTIVE.: To develop a low-dose computed tomography (CT) protocol for use in robot-assisted pediatric spinal surgery. SUMMARY OF BACKGROUND DATA: CT scans are utilized preoperatively for preoperative planning, by navigation software during robot-assisted surgery, and postoperatively to assess surgical implant placement. Traditionally high radiation doses produced by CT scanning are a concern in the highly radiosensitive pediatric population...
August 10, 2016: Spine
https://www.readbyqxmd.com/read/27439031/montelukast-for-children-with-obstructive-sleep-apnea-results-of-a-double-blind-randomized-placebo-controlled-trial
#13
Leila Kheirandish-Gozal, Hari P R Bandla, David Gozal
RATIONALE: Obstructive sleep apnea (OSA) is highly prevalent in children and is usually treated by adenotonsillectomy. Nonsurgical therapies for OSA consist primarily of antiinflammatory approaches and have gained popularity, but their efficacy remains to be critically examined. OBJECTIVES: To determine the effect of montelukast on pediatric OSA. METHODS: A prospective randomized double-blind controlled trial of polysomnographically diagnosed OSA in children ages 2-10 years who were treated with either oral montelukast (4 or 5 mg daily) or placebo for 16 weeks...
October 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27416322/reliable-and-developmentally-appropriate-study-end-points-are-needed-to-achieve-drug-development-for-treatment-of-pediatric-pulmonary-arterial-hypertension
#14
H Sun, N Stockbridge, R L Ariagno, D Murphy, R M Nelson, W Rodriguez
OBJECTIVE: To identify suitable end points and surrogates for pediatric pulmonary arterial hypertension (PAH) as the lack of developmentally appropriate end point and clinical trials contribute to the unmet medical need. STUDY DESIGN: Reviewed the efficacy end points and surrogates for all trials (1995 to 2013) that were submitted to the Food and Drug Administration (FDA) to support the approval of PAH therapy and conducted literature search. RESULTS: An increase in the 6 min walking distance (6MWD) was used as a primary end point in 8/9 adult PAH trials...
December 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27373823/influence-of-graft-ischemic-time-and-geographic-distance-between-donor-and-recipient-on-survival-in-children-after-lung-transplantation
#15
Don Hayes, Brian F Joy, Susan D Reynolds, Joseph D Tobias, Dmitry Tumin
BACKGROUND: The optimal ischemic time in pediatric lung transplantation (LTx) is unclear, as recent studies have challenged the relevance of 6 hours as an upper limit to acceptable ischemic time. METHODS: Pediatric LTx recipients transplanted between 1987 and 2013 were identified in the United Network for Organ Sharing (UNOS) registry to compare survival according to ischemic time, which was categorized as <4 hours, 4 to 6 hours and >6 hours. RESULTS: Nine hundred thirty patients, all <18 years of age and receiving a first-time LTx from a cadaveric donor, were included in our investigation...
May 27, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27348057/model-based-iterative-reconstruction-in-ultra-low-dose-pediatric-chest-ct-comparison-with-adaptive-statistical-iterative-reconstruction
#16
COMPARATIVE STUDY
Hae Jin Kim, So-Young Yoo, Tae Yeon Jeon, Ji Hye Kim
PURPOSE: To evaluate image quality and dose reduction of ultra-low-dose pediatric chest CT reconstructed with model-based iterative reconstruction (MBIR), as compared with adaptive statistical iterative reconstruction (ASIR). MATERIALS AND METHODS: Fifty-seven patients (mean age 14 years, M:F=31:26) who underwent ultra-low-dose chest CT reconstructed with both MBIR and ASIR were enrolled in the study. The subjective and objective image qualities of both reconstruction techniques were assessed by 3 radiologists, and compared using statistical analysis...
September 2016: Clinical Imaging
https://www.readbyqxmd.com/read/27347233/transphyseal-femoral-neck-fracture-in-a-twenty-month-old-male-child
#17
Matthew J Brown, Michael R Ferrick
Transphyseal femoral neck fractures are an extremely rare event, mainly occurring in children subjected to an significant traumatic force. The diagnosis is usually suggested by clinical examination with radiographic confirmation. Management varies; however, no consensus exists as to proper treatment. Intervention is primarily focused on the prevention of avascular necrosis (AVN) of the femoral epiphysis. We present the case of a 20-month-old male with a delayed diagnosis of transphyseal femoral neck fracture...
2016: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/27312248/a-comparative-study-of-two-percutaneous-pinning-techniques-lateral-vs-medial-lateral-for-gartland-type-iii-pediatric-supracondylar-fracture-of-the-humerus
#18
Kumar Prashant, Devendra Lakhotia, Tulsi Das Bhattacharyya, Anil Kumar Mahanta, Aakhil Ravoof
BACKGROUND: The management of displaced supracondylar fracture of the humerus with closed reduction and percutaneous pin fixation is the most widely accepted method of treatment, but controversy continues regarding the pin fixation techniques. A prospective randomized controlled study was undertaken to compare the stability, functional outcome and iatrogenic ulnar nerve injury between lateral pin fixation and medial-lateral pin fixation. MATERIAL AND METHOD: Sixty-two patients with Gartland type III supracondylar fracture of the humerus were randomized into two groups-lateral pin fixation (n = 31) and medial-lateral pin fixation (n = 31)...
September 2016: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/27289341/a-toolkit-for-pediatric-ct-dose-reduction-in-community-hospitals
#19
Diane Armao, Terry Hartman, Christopher M Shea, Cassandra Sams, Marija Ivanovic, Lynn Ansley Fordham, J Keith Smith
Pediatric CT radiation dose optimization is a challenging process for pediatric-focused facilities and community hospitals alike. Ongoing experience and trial-and-error approaches to dose reduction in the large academic hospital setting may position these centers to help community hospitals that strive for CT quality improvement. We describe our hands-on approach in a pilot project to create a partnership between an academic medical center and a community hospital to develop a toolkit for implementing CT dose reduction...
November 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27234569/take-a-breath-study-protocol-for-a-randomized-controlled-trial-of-an-online-group-intervention-to-reduce-traumatic-stress-in-parents-of-children-with-a-life-threatening-illness-or-injury
#20
Meredith Rayner, Frank Muscara, Anica Dimovski, Maria C McCarthy, Jackie Yamada, Vicki A Anderson, Kylie Burke, Robyn Walser, Jan M Nicholson
BACKGROUND: A substantial proportion of parents whose child is diagnosed with a life-threatening illness, experience high levels of distress that can lead to long-term difficulties in mental health, family functioning and child adjustment. This study evaluates the efficacy of an Acceptance Commitment Therapy-based group intervention designed to reduce distress symptoms in these parents. The program is delivered using videoconferencing to overcome factors that prevent participation in traditional face-to-face therapy...
2016: BMC Psychiatry
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