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https://www.readbyqxmd.com/read/29969293/group-cognitive-behavioral-therapy-and-attention-bias-modification-for-childhood-anxiety-disorders-a-factorial-randomized-trial-of-efficacy
#1
Giovanni A Salum, Circe S Petersen, Rafaela B Jarros, Rudineia Toazza, Diogo DeSousa, Lidiane Nunes Borba, Stela Castro, Julia Gallegos, Paula Barrett, Rany Abend, Yair Bar-Haim, Daniel S Pine, Silvia H Koller, Gisele G Manfro
BACKGROUND: The objective of this study is to assess group differences in symptom reduction between individuals receiving group cognitive behavioral therapy (G-CBT) and attention bias modification (ABM) compared to their respective control interventions, control therapy (CT), and attention control training (ACT), in a 2 × 2 factorial design. METHODS: A total of 310 treatment-naive children (7-11 years of age) were assessed for eligibility and 79 children with generalized, separation or social anxiety disorder were randomized and received G-CBT (n = 42) or CT (n = 37)...
July 3, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29958505/a-questionnaire-based-analysis-of-parental-perspectives-on-pediatric-cochlear-implant-ci-re-habilitation-services-a-pilot-study-from-a-developing-ci-service-in-india
#2
Apurva Nidgundi Dev, Usha Lohith, Brigetta Pascal, Chandrika S Dutt, Sunil Narayan Dutt
OBJECTIVE: To study parental perspectives on re/habilitation services offered for pediatric cochlear implant (CI) users at a non-profit organization in India. METHODOLOGY: A non-standardized questionnaire comprising 46 items was created to understand perspectives of parents of pediatric CI users. Questions were designed to examine re/habilitation services from the angles of service delivery, parental stress levels, reasons for delay in obtaining services, sources of emotional support, concerns, and fears during each stage starting from diagnosis of hearing loss to CI surgery, re/habilitation services and parents' views of their children post-CI...
June 29, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29949420/evaluating-lens-dose-reduction-in-pediatric-neuroradiology-examinations-using-automated-kilovoltage-selection-software
#3
Justin Raudabaugh, Aaron K Smith, Bria Moore, Juan Carlos Ramirez-Giraldo, Natalie Januzis, Terry Yoshizumi
OBJECTIVE: The purpose of this study is to evaluate the potential of an automated kilo-voltage selection software for the reduction of lens dose in pediatric CT scans. MATERIALS AND METHODS: Two metal oxide semiconductor field effect transistor (MOSFET) detectors measured the lens dose in two anthropomorphic 1- and 5-year-old phantoms. These phantoms were scanned using a clinical pediatric brain protocol at 120 kVp as a control with the MDCT scanner. Scans were then repeated using automated kilovoltage software...
June 27, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29933521/next-generation-sequencing-improves-treatment-efficacy-and-reduces-hospitalization-in-children-with-drug-resistant-epilepsy
#4
Jing Peng, Nan Pang, Ying Wang, Xiao-Le Wang, Jian Chen, Juan Xiong, Pan Peng, Can-Hui Zhu, Miriam Barakael Kessi, Fang He, Fei Yin
BACKGROUND: The purposes of this study were three-fold: (i) to determine the contribution of known genes to the causation of a broad-spectrum of pediatric drug-resistant epilepsy (DRE), (ii) to compare the diagnostic yield and cost among different next-generation sequencing (NGS) approaches, and especially (iii) to assess how NGS approaches can benefit patients by improving diagnosis and treatment efficiency. METHODS: This study enrolled 273 pediatric DRE patients with no obvious acquired etiology...
June 22, 2018: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29880034/bmi-z-score-in-obese-children-is-a-poor-predictor-of-adiposity-changes-over-time
#5
Cassandra Vanderwall, Jens Eickhoff, R Randall Clark, Aaron L Carrel
BACKGROUND: The age and sex standardized body mass index (BMIz) is a simple and widely utilized screening tool for obesity in children and adolescents. The purpose of this study was to evaluate the relationship between the BMIz trajectory versus the percent body fat (%FAT) trajectory, and if BMIz could predict significant changes in %FAT in a sample of obese children and adolescents. METHODS: In this longitudinal observational study, body composition was measured by dual energy x-ray absorptiometry (DXA) in obese children within a multidisciplinary pediatric fitness clinic at an academic medical center over a 3-year time period...
June 8, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29858509/technical-note-freect_icd-an-open-source-implementation-of-a-model-based-iterative-reconstruction-method-using-coordinate-descent-optimization-for-ct-imaging-investigations
#6
John M Hoffman, Frédéric Noo, Stefano Young, Scott S Hsieh, Michael McNitt-Gray
PURPOSE: To facilitate investigations into the impacts of acquisition and reconstruction parameters on quantitative imaging, radiomics and CAD using CT imaging, we previously released an open-source implementation of a conventional weighted filtered backprojection reconstruction called FreeCT_wFBP. Our purpose was to extend that work by providing an open-source implementation of a model-based iterative reconstruction method using coordinate descent optimization, called FreeCT_ICD. METHODS: Model-based iterative reconstruction offers the potential for substantial radiation dose reduction, but can impose substantial computational processing and storage requirements...
June 1, 2018: Medical Physics
https://www.readbyqxmd.com/read/29740810/development-of-a-caregiver-reported-experience-measure-for-pediatric-hospital-to-home-transitions
#7
Arti D Desai, Elizabeth A Jacob-Files, Sarah J Lowry, Douglas J Opel, Rita Mangione-Smith, Maria T Britto, Waylon J Howard
OBJECTIVE: To develop and test a caregiver-reported experience measure for pediatric hospital-to-home transitions. DATA SOURCES/STUDY SETTING: Primary data were collected between 07/2014 and 05/2015 from caregivers within 2-8 weeks of their child's discharge from a tertiary care children's hospital. STUDY DESIGN/DATA COLLECTION: We used a step-wise approach to developing the measure that included drafting de novo survey items based on caregiver interviews (n = 18), pretesting items using cognitive interviews (n = 18), and pilot testing revised items among an independent sample of caregivers (n = 500)...
May 8, 2018: Health Services Research
https://www.readbyqxmd.com/read/29727767/bioabsorbable-plating-in-the-treatment-of-pediatric-clavicle-fractures-a-biomechanical-and-clinical-analysis
#8
Emily J Osborn, Christine L Farnsworth, Joshua D Doan, Eric W Edmonds
BACKGROUND: Classic implants for operative intervention of mid-shaft clavicle fractures in adolescents can become symptomatic, requiring removal. This study compares 1) biomechanical properties and 2) clinical outcomes in adolescents of mid-shaft clavicle fracture fixation with bioabsorbable versus metal implants. METHODS: Six synthetic clavicles with mid-shaft fractures underwent bioabsorbable plating. A testing frame applied 10 non-destructive torsion and 10 axial compression cycles, followed by cantilever bending to failure...
June 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29720908/implementation-and-impact-of-an-antimicrobial-stewardship-program-at-a-non-freestanding-children-s-hospital
#9
J Michael Klatte, Kathleen Kopcza, Alexander Knee, Evan R Horton, Erica Housman, Donna J Fisher
OBJECTIVES: Pediatric Antimicrobial Stewardship Programs (ASP) have been associated with improvements in antibiotic utilization and patient outcomes; however, ASP studies originating from non-freestanding children's hospitals are lacking. In this study, we present the implementation and impact of a multidisciplinary ASP that employs a collaborative physician and pharmacist driven thrice-weekly prospective audit-with-feedback approach at a non-freestanding children's hospital. METHODS: Implementation was assessed via descriptive design...
March 2018: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/29698303/closed-reduction-osteotomy-and-fibular-graft-are-effective-in-treating-pediatric-femoral-neck-pseudarthrosis-after-infection
#10
Rajesh Kumar Kanojia, Sumit Gupta, Ajay Kumar, Bachha Kanakeya Reddy
BACKGROUND: When treatment of acute septic arthritis of the hip is delayed, severe sequelae can occur. This may take the form of coxa breva, vara, or valga. Pseudoarthrosis of the femoral neck is a rare complication with only a few studies to guide treatment. QUESTION/PURPOSES: In a small series of patients with pseudarthrosis of the femoral neck after acute septic arthritis, we wanted to determine (1) whether femoral neck union can be achieved using a variety of surgical approaches; (2) whether these patients satisfied criteria outlined by Hunka and Choi, defined as a stable hip, a flexion arc ≥ 70° and no fixed adduction or abduction contractures, fixed flexion deformity not more than 20°, pain relief, and restoration of activities of daily living after surgery; and (3) any treatment-related complications if observed...
July 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29685491/initial-development-and-validation-of-a-fecal-incontinence-specific-quality-of-life-measure
#11
Christopher C Cushing, Melody R S Threlkeld, Bruno Martinez-Leo, Jennifer Hall, Monir Hossain, Belinda H Dickie, Beth Rymeski, Michael Helmrath, Meg H Zeller, Jason S Frischer
BACKGROUND/PURPOSE: Fecal incontinence is a prevalent pediatric condition with psychosocial impacts on both children and their caregivers. We sought to develop and validate the Cincinnati Fecal Incontinence Scale (CINCY-FIS) as a psychometrically valid measure to assess the quality of life and caregiver impacts of pediatric fecal incontinence. METHODS: Items were generated through review of previous measures, expert consensus, and pilot testing with feedback from 8 families...
June 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29629048/prophylactic-effect-of-riboflavin-on-pediatric-migraine-a-randomized-double-blind-placebo-controlled-trial
#12
Ahmad Talebian, Babak Soltani, Hamid Reza Banafshe, Gholam Abbas Moosavi, Motahhareh Talebian, Siamak Soltani
Background and aim: Riboflavin may have an acceptable effect on migraine among children. This study was carried out to determine the prophylactic effect of riboflavin on migraine in children. Methods: This randomized clinical trial study was performed at Shahid Beheshti Hospital in Kashan, Iran from December 2012 to February 2015. Ninety children with migraine were allocated randomly into 3 groups (placebo, low-dose and high-dose riboflavin). The outcomes (frequency, intensity and duration of headaches) were measured at baseline and 12 weeks of medication in each group, and the decrease of them were compared...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29605825/potassium-citrate-is-better-in-reducing-salt-and-increasing-urine-ph-than-oral-intake-of-lemonade-a-cross-over-study
#13
Jing Shen, Xicheng Zhang
BACKGROUND Urine solute supersaturation leads to the formation of urinary tract caliceal stones. Many parameters can be involved in the supersaturation of solutes in urine, such as pH. Uric acid has pKa ≤5.5, and it is solubilized at pH ≥5.5. The objective of the study was to evaluate the effects of potassium citrate and lemonade supplementation in pediatric patients with urolithiasis. MATERIAL AND METHODS A total of 126 children who had lower ureteral stones calculi and fragments with severe colic pain participated in this cross-over study...
April 1, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29562929/the-influence-of-an-accredited-pediatric-emergency-medicine-program-on-the-management-of-pediatric-pain-and-anxiety
#14
Tali Capua, Zohar Bar Kama, Ayelet Rimon
BACKGROUND: The emergency department (ED) setting is an environment where children may experience intense physical pain and emotional stress. This study sought to determine the availability of pain and anxiety management practices in all Israeli emergency departments which accept children, specifically looking for differences between accredited pediatric emergency medicine departments and others. METHODS: A cross-sectional survey of all Israeli emergency departments that accept children was performed...
March 21, 2018: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29552422/diabetes-empowerment-council-integrative-pilot-intervention-for-transitioning-young-adults-with-type-1-diabetes
#15
Marc J Weigensberg, Cheryl Vigen, Paola Sequeira, Donna Spruijt-Metz, Magaly Juarez, Daniella Florindez, Joseph Provisor, Anne Peters, Elizabeth A Pyatak
Background: The transition of young adults with type 1 diabetes (T1D) from pediatric to adult care is challenging and frequently accompanied by worsening of diabetes-related health. To date, there are no reports which prospectively assess the effects of theory-based psycho-behavioral interventions during the transition period neither on glycemic control nor on psychosocial factors that contribute to poor glycemic control. Therefore, the overall aim of this study was to develop and pilot test an integrative group intervention based on the underlying principles of self-determination theory (SDT), in young adults with T1D...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/29402854/feasibility-validity-and-reliability-of-the-italian-pediatric-quality-of-life-inventory-multidimensional-fatigue-scale-for-adults-in-inpatients-with-severe-obesity
#16
Gian Mauro Manzoni, Alessandro Rossi, Nicoletta Marazzi, Fiorenza Agosti, Alessandra De Col, Giada Pietrabissa, Gianluca Castelnuovo, Enrico Molinari, Allessandro Sartorio
OBJECTIVE: This study was aimed to examine the feasibility, validity, and reliability of the Italian Pediatric Quality of Life Inventory Multidimensional Fatigue Scale (PedsQL™ MFS) for adult inpatients with severe obesity. METHODS: 200 inpatients (81% females) with severe obesity (BMI ≥ 35 kg/m2) completed the PedsQL MFS (General Fatigue, Sleep/Rest Fatigue and Cognitive Fatigue domains), the Fatigue Severity Scale, and the Center for Epidemiologic Studies Depression Scale immediately after admission to a 3-week residential body weight reduction program...
2018: Obesity Facts
https://www.readbyqxmd.com/read/29329282/induction-of-high-mobility-group-box-1-in-vitro-and-in-vivo-by-respiratory-syncytial-virus
#17
Sara Manti, Terri J Harford, Carmelo Salpietro, Fariba Rezaee, Giovanni Piedimonte
BackgroundDespite decades that have passed since its discovery, accurate biomarkers of respiratory syncytial virus (RSV) disease activity and effective therapeutic strategies are still lacking. The high-mobility group box type 1 (HMGB1) protein has been proposed as a possible link between RSV and immune system, but only limited information is currently available to support this hypothesis.MethodsExpression of HMGB1 gene and protein was analyzed by quantitative PCR, enzyme-linked immunosorbent assay (ELISA), western blot, immunocytochemistry, and confocal microscopy in immortalized and primary human bronchial epithelial cells, as well as in rat pup lungs...
May 2018: Pediatric Research
https://www.readbyqxmd.com/read/29282591/performance-of-regional-oxygen-saturation-monitoring-by-near-infrared-spectroscopy-nirs-in-pediatric-inter-hospital-transports-with-special-reference-to-air-ambulance-transports-a-methodological-study
#18
Tova Hannegård Hamrin, Peter J Radell, Urban Fläring, Jonas Berner, Staffan Eksborg
The aim of the present study was to evaluate the performance of regional oxygen saturation (rSO2 ) monitoring with near infrared spectroscopy (NIRS) during pediatric inter-hospital transports and to optimize processing of the electronically stored data. Cerebral (rSO2 -C) and abdominal (rSO2 -A) NIRS sensors were used during transport in air ambulance and connecting ground ambulance. Data were electronically stored by the monitor during transport, extracted and analyzed off-line after the transport. After removal of all zero and floor effect values, the Savitzky-Golay algorithm of data smoothing was applied on the NIRS-signal...
December 28, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29279946/adaptive-statistical-iterative-reconstruction-use-for-radiation-dose-reduction-in-pediatric-lower-extremity-ct-impact-on-diagnostic-image-quality
#19
Amisha Shah, Mitchell Rees, Erica Kar, Kimberly Bolton, Vincent Lee, Ashok Panigrahy
BACKGROUND: For the past several years, increased levels of imaging radiation and cumulative radiation to children has been a significant concern. Although several measures have been taken to reduce radiation dose during computed tomography (CT) scan, the newer dose reduction software adaptive statistical iterative reconstruction (ASIR) has been an effective technique in reducing radiation dose. To our knowledge, no studies are published that assess the effect of ASIR on extremity CT scans in children...
June 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29278646/impact-of-dietary-nutrient-intake-and-physical-activity-on-body-composition-and-growth-in-indian-children
#20
Anuradha V Khadilkar, Shashi A Chiplonkar, Neha A Kajale, Veena H Ekbote, Lavanya Parathasarathi, Raja Padidela, Vaman V Khadilkar
BackgroundTo investigate interrelationships of dietary composition and physical activity (PA) with growth and body composition (BC) in urban Indian school children.MethodsA cross-sectional study was performed in 4,747 Indian school children (2,623 boys) aged 3-18 years. Weight, height, BC by body impedance analyzer, PA and dietary food intakes by questionnaire method were recorded.ResultsMean daily energy and protein intakes as recommended dietary allowance were significantly lower in both boys and girls (P<0...
April 2018: Pediatric Research
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