Saleh Fahad Alqifari, Omar Alkomi, Abdullah Esmail, Khadijeh Alkhawami, Shahd Yousri, Mohamad Ayham Muqresh, Nawwarah Alharbi, Abdullah A Khojah, Ahmed Aljabri, Abdulrahman Allahham, Kousalya Prabahar, Hanan Alshareef, Mohammed Aldhaeefi, Tariq Alrasheed, Ali Alrabiah, Laila A AlBishi
In 2005, exenatide became the first approved glucagon-like peptide-1 receptor agonist (GLP-1 RA) for type 2 diabetes mellitus (T2DM). Since then, numerous GLP-1 RAs have been approved, including tirzepatide, a novel dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RA, which was approved in 2022. This class of drugs is considered safe with no hypoglycemia risk, making it a common second-line choice after metformin for treating T2DM. Various considerations can make selecting and switching between different GLP-1 RAs challenging...
March 15, 2024: World Journal of Diabetes