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pine nut allergy

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https://www.readbyqxmd.com/read/26948687/identification-and-characterization-of-dc-sign-binding-glycoproteins-in-allergenic-foods
#1
M Kamalakannan, L M Chang, G Grishina, H A Sampson, M Masilamani
BACKGROUND: DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin) is a C-type lectin receptor expressed on macrophages and dendritic cells. DC-SIGN has high affinity for fucosylated glycans in several plant glycoproteins and pathogens. DC-SIGN is thought to be crucial for the development of allergic sensitization. However, the precise role of DC-SIGN in food allergy pathogenesis is not yet understood. OBJECTIVE: We sought to characterize DC-SIGN-binding glycoproteins in a panel of allergenic and non-allergenic foods...
August 2016: Allergy
https://www.readbyqxmd.com/read/26727761/allergic-reactions-to-pine-nut-a-review
#2
REVIEW
B Cabanillas, N Novak
Pine nut is a nutrient-rich food with a beneficial impact on human health. The many bioactive constituents of pine nut interact synergistically to affect human physiology in a favorable way. However, pine nut can trigger dangerous allergic reactions. Severe anaphylactic reactions to pine nut accounted for most of the 45 cases reported in the scientific literature. Pine nut allergy seems to be characterized by low IgE cross-reactivity with other commonly consumed nuts and a high monosensitization rate. The present review provides updated information on allergic reactions to pine nut, molecular characterization of its allergens, and potential homologies with other nut allergens...
2015: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/24328105/crystal-structure-of-korean-pine-pinus-koraiensis-7s-seed-storage-protein-with-copper-ligands
#3
Tengchuan Jin, Yang Wang, Yu-Wei Chen, Tong-Jen Fu, Mahendra H Kothary, Tara H McHugh, Yuzhu Zhang
The prevalence of food allergy has increased in recent years, and Korean pine vicilin is a potential food allergen. We have previously reported the crystallization of Korean pine vicilin purified from raw pine nut. Here we report the isolation of vicilin mRNA and the crystal structure of Korean pine vicilin at 2.40 Å resolution. The overall structure of pine nut vicilin is similar to the structures of other 7S seed storage proteins and consists of an N-terminal domain and a C-terminal domain. Each assumes a cupin fold, and they are symmetrically related about a pseudodyad axis...
January 8, 2014: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/24129043/heterogenity-of-ige-response-to-walnut-and-hazelnut-in-italian-allergic-patients
#4
R Asero, A Arena, M Cervone, M Crivellaro, F Lodi Rizzini, R Longo, D Macchia, G Manzotti, P Minale, F Murzilli, B R Polillo, V Pravettoni, E Ridolo, E Savi, D Villalta, S Amato, G Mistrello
Background: The prevalence of IgE reactivity against genuine walnut and hazelnut allergens  is poorly defined. Objective: The IgE response to walnut and hazelnut was investigated in Italian patients with primary allergy to these nuts. Methods: Sera from 36 patients allergic to hazelnut and/or walnut, not reactive to PR-10, profilin, and LTP, underwent immunoblot analysis with extracts of both nuts. Results: Most patients had a history of systemic symptoms following the ingestion of the offending food(s). Twelve patients were sensitized to both walnut and hazelnut, and  13 were sensitized to other nuts and seeds  (cashew, peanut, sesame, pine nut, almond, Brazil nut, and pistachio)...
October 2013: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/23106493/children-monosensitized-to-pine-nuts-have-similar-patterns-of-sensitization
#5
Elio Novembre, Francesca Mori, Simona Barni, Giuliana Ferrante, Neri Pucci, Cinzia Ballabio, Francesca Uberti, Elena Penas, Patrizia Restani
BACKGROUND: Several cases of pine nut allergies and anaphylaxis have been reported in the literature, but only few pine nut allergens have been characterized. The aim of this research is to identify through immunoelectrophoretic techniques the major pine nut allergens in a group of children monosensitized to pine nuts. METHODS: We studied five children with pine nut allergies and no other sensitization to food except to pine nuts, confirmed by in vivo (prick test, prick-to-prick) and in vitro tests (specific IgE determinations [CAP-FEIA])...
December 2012: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/23081934/pine-nut-allergy-clinical-features-and-major-allergens-characterization
#6
RANDOMIZED CONTROLLED TRIAL
Beatriz Cabanillas, Hsiaopo Cheng, Casey C Grimm, Barry K Hurlburt, Julia Rodríguez, Jesús F Crespo, Soheila J Maleki
SCOPE: The aims of this study were to evaluate IgE-mediated hypersensitivity to pine nut with details of clinical reactions and to characterize major pine nut allergens. METHODS AND RESULTS: The study included ten consecutive teenagers and adults diagnosed with IgE-mediated clinical allergy to pine nut. Two major pine nut allergens were purified and identified and the secondary structures and susceptibility to digestion were characterized. Severe reactions represent 80% of allergic reactions to pine nut in this study...
December 2012: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/19810428/a-not-so-healthy-muesli-a-case-report
#7
M Meysman, D Schelfaut, W Vincken
We present a patient with severe anaphylaxis, angioedema, hypotension and shock. The near fatal allergic reaction was caused by eating yogurt with muesli containing pine nuts. The patient developed an acute infero-posterolateral myocardial infarction due to systemic hypotension and shock. Food allergy to pine nut was demonstrated by dosage of specific IgE to pine nut.
July 2009: Acta Clinica Belgica
https://www.readbyqxmd.com/read/18690685/purification-and-characterization-of-the-7s-vicilin-from-korean-pine-pinus-koraiensis
#8
Tengchuan Jin, Silvia M Albillos, Yu-Wei Chen, Mahendra H Kothary, Tong-Jen Fu, Yu-Zhu Zhang
Pine nuts are economically important as a source of human food. They are also of medical importance because numerous pine nut allergy cases have been recently reported. However, little is known about the proteins in pine nuts. The purpose of this study was to purify and characterize pine nut storage proteins. Reported here is the first detailed purification protocol of the 7S vicilin-type globulin from Korean pine (Pinus koraiensis) by gel filtration, anion exchange, and hydrophobic interaction chromatography...
September 10, 2008: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/18386436/a-case-of-severe-allergy-to-pine-nut
#9
G Rossi
A case is reported of a patient who showed an immediate allergic reaction after ingestion of pine nut at the age of 38. Subsequently she developed acute allergic symptoms also by inhalation of the allergen, without food ingestion. Finally, the patient showed an acute systemic allergic reaction immediately after skin testing with fresh pine nut.
December 2007: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/12915766/tree-nut-allergens
#10
REVIEW
Kenneth H Roux, Suzanne S Teuber, Shridhar K Sathe
Allergic reactions to tree nuts can be serious and life threatening. Considerable research has been conducted in recent years in an attempt to characterize those allergens that are most responsible for allergy sensitization and triggering. Both native and recombinant nut allergens have been identified and characterized and, for some, the IgE-reactive epitopes described. Some allergens, such as lipid transfer proteins, profilins, and members of the Bet v 1-related family, represent minor constituents in tree nuts...
August 2003: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/12911512/anaphylaxis-induced-by-pine-nuts-in-two-young-girls
#11
M Dolores Ibáñez, Manuel Lombardero, Mercedes Martinez San Ireneo, M Carmen Muñoz
Pine nuts are the seeds of Pinus pinea. There are few reported cases of allergy to pine nut. We describe two young girls with anaphylaxis caused by small amounts of pine nuts. Specific IgE to pine nut was demonstrated by skin prick tests and RAST but no IgE to other nuts and pine pollen was detected. The patients had IgE against a pine nut protein band with apparent molecular weights of approximately 17 kDa that could be considered as the main allergen. Our patients were monosensitized to pine nut and the 17-kDa protein could be correlated with the severe clinical symptoms...
August 2003: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/11958743/allergy-to-pine-nut
#12
M A Añó, J P Maselli, M L Sanz, M Fernández-Benítez
BACKGROUND: food allergy is highly prevalent in our environment, especially among atopic patients. Pinus pinea is common in our region and its fruit, the pine nut, is allergologically important. Several cases have been reported in the literature that demonstrate the existence of common antigenic bands between pine nut and almond. In this study we try to assess this finding and the possible existence of common allergens by in vitro techniques. METHODS AND RESULTS: we present a 10-year-old boy, previously diagnosed of seasonal rhinoconjunctivitis with sensitisation to grass and olive pollen, who had an anaphylactic reaction after eating pine nut...
March 2002: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/10780800/anaphylaxis-to-pine-nuts-and-immunological-cross-reactivity-with-pine-pollen-proteins
#13
G Senna, D Roncarolo, A Dama, G Mistrello
Despite the wide use of pine nuts, the fruit of Pinus pinea, only a few reports of allergic reactions to them have been published. We present herein a case of food allergy to pine nuts in a patient who showed no clinical symptoms to pine pollen despite the presence in her serum of specific IgE antibodies. In order to verify whether the reaction against pine nuts was IgE mediated, specific IgE against pine nuts and pollen were evaluated by skin-prick test, prick by prick and RAST. Immunoblotting and immunoblotting-inhibition were used to evaluate the allergenic components of both extracts and their cross-reactivity...
January 2000: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/10753022/a-17-kda-allergen-detected-in-pine-nuts
#14
J M García-Menaya, M A Gonzalo-Garijo, I Moneo, B Fernández, F García-González, F Moreno
BACKGROUND: Few cases of allergy to pine nuts have been described. We report a case of anaphylactic reaction to pine nuts. The patient needed to be treated in the emergency room due to a systemic reaction immediately after eating pine nuts. METHODS: The patient was studied by prick tests and prick by prick tests. Specific IgE was measured by CAP and by SDS-PAGE/immunoblotting by a diffusion method. RESULTS: The patient showed positive prick by prick tests to pine nuts (12 mm of maximum wheal diameter)...
March 2000: Allergy
https://www.readbyqxmd.com/read/9823420/allergy-to-pine-nuts-in-children
#15
REVIEW
N Rubira, J Botey, J L Eseverri, A Marin
BACKGROUND: Allergy to nuts is a common and well-known disease. Despite the fact that pine nut is a widely eaten food, only nine cases have been described in literature. OBJECTIVE: To describe four paediatric patients suffering from allergy reaction on ingestion of pine nuts and compare them with cases described in literature, taking into account clinical symptoms, epidemiological and diagnostic methods. METHODS: The immuno-allergic study was carried out with skin tests (prick tests) using a commercial and native extract, and specific IgE serum test...
September 1998: Allergie et Immunologie
https://www.readbyqxmd.com/read/9534929/allergy-to-pine-nuts
#16
D de las Marinas, L Vila, M L Sanz
No abstract text is available yet for this article.
February 1998: Allergy
https://www.readbyqxmd.com/read/8905003/allergy-to-pine-nuts-in-a-bird-fancier
#17
A Jansen, A Vermeulen, P H Dieges, A W van Toorenenbergen
A patient is described with the bird-egg syndrome who experienced an anaphylactic reaction after eating some of her parrot's food (pine nuts: Pinus pinea). Specific IgE against this nut and another pine nut (P. cembra) was demonstrated by RAST. Cross-reactivity between these botanically related seeds was shown by RAST inhibition. Besides avian antigens, bird food antigens should be taken into consideration when symptoms of allergy occur on exposure to birds.
October 1996: Allergy
https://www.readbyqxmd.com/read/2923327/pine-nut-allergy-in-perspective
#18
C J Falliers
Anaphylaxis and other acute allergic reactions following the ingestion of pine--or pinon--nuts are documented and reviewed in perspective. Systemic allergic reactions to other relatively uncommon or "exotic" foods are also considered. Although hypersensitivity to more than one type of "nuts" is reported by some individuals, no significant cross-reactivity between any of these, or between pine pollen, pine resin, and pine nuts has been demonstrated.
March 1989: Annals of Allergy
https://www.readbyqxmd.com/read/2297145/allergy-to-pine-pollen-and-pinon-nuts-a-review-of-three-cases
#19
A Armentia, A Quintero, A Fernández-García, J Salvador, J M Martín-Santos
No abstract text is available yet for this article.
January 1990: Annals of Allergy
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