keyword
MENU ▼
Read by QxMD icon Read
search

musculoskeletal injections

keyword
https://www.readbyqxmd.com/read/29150470/platelet-rich-plasma-in-achilles-tendon-healing-2-path-2-trial-protocol-for-a-multicentre-participant-and-assessor-blinded-parallel-group-randomised-clinical-trial-comparing-platelet-rich-plasma-prp-injection-versus-placebo-injection-for-achilles-tendon-rupture
#1
Joseph Alsousou, David J Keene, Philippa A Hulley, Paul Harrison, Susan Wagland, Christopher Byrne, Michael Maia Schlüssel, Susan J Dutton, Sarah E Lamb, Keith Willett
BACKGROUND: Achilles tendon injuries give rise to substantial long-lasting morbidity and pose considerable challenges for clinicians and patients during the lengthy healing period. Current treatment strategies struggle to curb the burden of this injury on health systems and society due to lengthy rehabilitation, work absence and reinjury risk. Platelet-rich plasma (PRP) is an autologous preparation that has been shown to improve the mechanobiological properties of tendons in laboratory and animal studies...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29112534/il1%C3%AE-inhibition-contributes-to-the-anti-nociceptive-effects-of-voluntary-exercise-on-ischemia-reperfusion-induced-hypersensitivity
#2
Jessica L Ross, Luis F Queme, Jordan E Lamb, Kathryn J Green, Zachary K Ford, Michael P Jankowski
Issues of peripheral circulation have been increasingly suggested as an underlying cause of musculoskeletal pain in many conditions, including sickle cell anemia and peripheral vascular disease. We have previously shown in our model of transient ischemia and reperfusion injury (I/R) of the forelimb that individual group III and IV muscle afferents display altered chemosensitivity and mechanical thresholds 1 d following injury. Functional alterations corresponded to increased evoked and spontaneous pain-related behaviors and decreased muscle strength and voluntary activity-all actions that echo clinical symptoms of ischemic myalgia...
October 30, 2017: Pain
https://www.readbyqxmd.com/read/29101774/dextrose-prolotherapy-for-chronic-shoulder-pain-a-case-report
#3
Casey Seenauth, Vance Inouye, Jeffrey O Langland
Context • Shoulder pain is one of the most common pain complaints reported by patients. Consensus is lacking on its ideal treatment, and many different treatments are available and used. Prolotherapy is an injection-based therapy that has shown significant results in treating many common musculoskeletal pain conditions, including osteoarthritis, lateral epicondylosis, and low-back pain. Objective • The study intended to evaluate the use of dextrose prolotherapy in the treatment of shoulder pain. Design • The research team performed a case study...
November 4, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29063827/subcutaneous-injection-of-adalimumab-trial-compared-with-control-sciatic-a-randomised-controlled-trial-of-adalimumab-injection-compared-with-placebo-for-patients-receiving-physiotherapy-treatment-for-sciatica
#4
Nefyn H Williams, Alison Jenkins, Nia Goulden, Zoe Hoare, Dyfrig A Hughes, Eifiona Wood, Nadine E Foster, David A Walsh, Dawn Carnes, Valerie Sparkes, Elaine M Hay, John Isaacs, Kika Konstantinou, Dylan Morrissey, Jaro Karppinen, Stephane Genevay, Clare Wilkinson
BACKGROUND: Biological treatments such as adalimumab (Humira(®); AbbVie Ltd, Maidenhead, UK) are antibodies targeting tumour necrosis factor alpha, released from ruptured intervertebral discs, which might be useful in sciatica. Recent systematic reviews concluded that they might be effective, but that a definitive randomised controlled trial was needed. Usual care in the NHS typically includes a physiotherapy intervention. OBJECTIVES: To test whether or not injections of adalimumab plus physiotherapy are more clinically effective and cost-effective than injections of saline plus physiotherapy for patients with sciatica...
October 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29027984/the-effect-of-intra-articular-injection-of-autologous-microfragmented-fat-tissue-on-proteoglycan-synthesis-in-patients-with-knee-osteoarthritis
#5
Damir Hudetz, Igor Borić, Eduard Rod, Željko Jeleč, Andrej Radić, Trpimir Vrdoljak, Andrea Skelin, Gordan Lauc, Irena Trbojević-Akmačić, Mihovil Plečko, Ozren Polašek, Dragan Primorac
Osteoarthritis (OA) is one of the leading musculoskeletal disorders in the adult population. It is associated with cartilage damage triggered by the deterioration of the extracellular matrix tissue. The present study explores the effect of intra-articular injection of autologous microfragmented adipose tissue to host chondrocytes and cartilage proteoglycans in patients with knee OA. A prospective, non-randomized, interventional, single-center, open-label clinical trial was conducted from January 2016 to April 2017...
October 13, 2017: Genes
https://www.readbyqxmd.com/read/28990574/an-evidence-based-evaluation-on-the-use-of-platelet-rich-plasma-in-orthopedics-a-review-of-the-literature
#6
Nasir Hussain, Herman Johal, Mohit Bhandari
Within orthopedics, the use of platelet-rich plasma (PRP) has been rapidly increasing in popularity, however, its true effectiveness has yet to be fully established. Several studies find that injecting PRP to the site of injury does not provide any significant benefit with respect to clinical outcomes; however, many others report the contrary. Due to the conflicting evidence and multiple meta-analyses conducted on the topic, a literature review of high-quality evidence on the use of PRP for common orthopaedic conditions was performed...
2017: SICOT-J
https://www.readbyqxmd.com/read/28988225/persistent-de-quervain-tenosynovitis-induced-by-somatotropin-treatment
#7
Ozan Volkan Yurdakul, Lütfiye Aytüre, Ebru Yilmaz Yalçinkaya
BACKGROUND: Growth hormone deficiency is a well-known clinical entity that is usually treated with somatotropin (growth hormone). Growth hormone has some frequent side effects such as intracranial hypertension, lymphedema and diabetes mellitus. CASE PRESENTATION: We report the case of a 14-year-old girl with a history of wrist pain and clumsiness. Magnetic resonance imaging revealed de Quervain tenosynovitis. The patient had a history of using growth hormones for 12 months...
October 26, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28987659/relationship-between-radiologist-training-level-and-radiation-exposure-for-therapeutic-hip-injections
#8
Brendan S P Sanders, Matthew D F McInnes, Marcos Loreto Sampaio, Kawan S Rakhra
OBJECTIVE: The aim of this study was to determine the relationship between the level of training of the performing radiologist and patient radiation exposure, as measured by fluoroscopy time (FT) and dose area product (DAP), during fluoroscopic guided hip injections. MATERIALS AND METHODS: This IRB-approved retrospective review of our institutional radiology report database identified all fluoroscopic guided hip injections performed between August 1st, 2012 and May 30th, 2015...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28979593/analysis-of-the-clinical-outcome-of-arthrographic-steroid-injection-for-the-treatment-of-adhesive-capsulitis
#9
Allison Tucker, Hiscox Christina, AlQahtani Saad, Ryan Bicknell
BACKGROUND: Idiopathic adhesive capsulitis is a condition of uncertain etiology characterized by pain and decreased shoulder range of motion (ROM) that occurs without a known intrinsic disorder. Many treatments have been advocated, yet the best option remains unclear. The purpose of this study was to determine if arthrographic injection of the shoulder joint with steroid and local anesthetic results in decreased pain and increased shoulder function in a cohort of patients with idiopathic adhesive capsulitis...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28937277/injectable-viscoelastic-supplements-a-review-for-radiologists
#10
REVIEW
Dermot J Bowden, Caoimhe A Byrne, Abdullah Alkhayat, Stephen J Eustace, Eoin C Kavanagh
OBJECTIVE: Hyaluronic acid (HA) is increasingly used by musculoskeletal radiologists in the treatment of osteoarthritis (OA). Although the evidence base for its efficacy is controversial, it remains in common use. With initial evidence suggesting its efficacy in the knee, it is now offered for treating OA of the hip, ankle, and elsewhere. CONCLUSION: HA is available in a wide variety of preparations, which may vary in concentration and chemical composition. Clinicians offering intraarticular HA injection should be familiar with the common preparations available and the principal differences between them, its mechanism of action, and the profile of adverse effects associated with its use...
October 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28916228/cellular-therapy-injections-in-today-s-orthopedic-market-a-social-media-analysis
#11
Prem N Ramkumar, Sergio M Navarro, Heather S Haeberle, Morad Chughtai, Christopher Demetriades, Nicolas S Piuzzi, Michael A Mont, Thomas W Bauer, George F Muschler
BACKGROUND: The current state of cellular therapy for musculoskeletal conditions is at a crossroads. Marketing efforts are often outpacing clinical evidence and regulatory control. QUESTIONS/PURPOSES: This study was an effort to describe the marketing of cellular therapy in musculoskeletal medicine by evaluating the content in popular social media channels. Specifically, media posts were evaluated for the following: (1) perspective, (2) tone, (3) content and (4) visibility...
September 12, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28895673/the-effect-of-interferential-current-therapy-on-patients-with-subacromial-impingement-syndrome-a-randomized-double-blind-sham-controlled-study
#12
Tuba Nazligul, Pinar Akpinar, Ilknur Aktas, Feyza Unlu Ozkan, Hulya Cagliyan Hartevioglu
BACKGROUND: Although interferential current (IFC) is a common electrotherapeutic modality used to treat musculoskeletal pain, there is not any randomized controlled trial investigating its clinical efficacy in subacromial impingement syndrome (SAIS). AIM: Investigation of effectiveness of IFC treatment in patients with SAIS. DESIGN: Randomized, double-blind, sham-controlled study. SETTING: Physical medicine and rehabilitation outpatient clinic...
September 11, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28893220/the-added-value-of-musculoskeletal-ultrasound-to-clinical-evaluation-in-the-treatment-decision-of-rheumatoid-arthritis-outpatients-physician-experience-matters
#13
C Sifuentes-Cantú, I Contreras-Yáñez, L Saldarriaga, A C Lozada, M Gutiérrez, V Pascual-Ramos
BACKGROUND: Musculoskeletal ultrasound improves the accuracy of detecting the level of disease activity (DA) in RA patients, although its impact on the final treatment decision in a real clinical setting is uncertain. The objectives were to define the percentage of clinical scenarios from an ongoing cohort of RA outpatients in which the German Ultrasound Score on 7 joints (GUS-7) impacted the treatment and to explore if the impact differed between a senior rheumatologist (SR) vs. a trainee (TR)...
September 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28885963/three-year-analysis-of-value-and-utilization-after-development-of-an-ultrasound-based-orthopedic-injection-clinic
#14
Chase Dukes, Thomas Melton, Eric Turner, Andrew Jackson, Jason Grassbaugh, John Slevin, Edward D Arrington, Josef K Eichinger
INTRODUCTION: Sonography is an effective method of diagnosing and treating musculoskeletal conditions, and the use of ultrasound has been shown to improve the accuracy, safety, and efficacy of both therapeutic and diagnostic injections. In 2012, we established an injection clinic at our institution to address our growing need for diagnostic and therapeutic injections. METHODS: We performed an analysis of value and utilization following the development of an orthopedic injection clinic...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28865187/sustained-release-of-multicomponent-platelet-rich-plasma-proteins-from-hydrolytically-degradable-peg-hydrogels
#15
Era Jain, Saahil Sheth, Andrew Dunn, Silviya P Zustiak, Scott A Sell
Platelet-rich plasma (PRP), an autologous blood derived product is a concentrated mix of multiple growth factors and cytokines. Direct injections of PRP are clinically used for treatment of various musculoskeletal disorders and in wound healing. However, PRP therapy has met with limited clinical success possibly due to unpredictable and premature bolus delivery of PRP growth factors. The objective of this study was to predictably control the bioavailability of PRP growth factors using a hydrolytically degradable polyethylene glycol (PEG) hydrogel...
December 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28763567/low-intensity-extracorporeal-shock-wave-therapy-promotes-myogenesis-through-perk-atf4-pathway
#16
Bohan Wang, Jun Zhou, Lia Banie, Amanda B Reed-Maldonado, Hongxiu Ning, Zhihua Lu, Yajun Ruan, Tie Zhou, Hsun Shuan Wang, Byung Seok Oh, Guifang Wang, Stanley Lei Qi, Guiting Lin, Tom F Lue
AIM: Stress urinary incontinence (SUI) is a significant health problem for women. Treatments employing muscle derived stem cells (MDSCs) may be a promising approach to this prevalent, bothersome condition, but these treatments are invasive and require collection of cells from one site for injection into another. It is also unknown whether or not these cells establish themselves and function as muscle cells in the target tissues. Alternatively, low-intensity extracorporeal shock wave therapy (Li-ESWT) is non-invasive and has shown positive outcomes in the treatment of multiple musculoskeletal disorders, but the biological effects responsible for clinical success are not yet well understood...
August 1, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28744328/ultrasonographic-imaging-and-anti-inflammatory-therapy-of-muscle-and-tendon-injuries-using-polymer-nanoparticles
#17
Gi-Wook Kim, Changsun Kang, Young-Bin Oh, Myoung-Hwan Ko, Jeong-Hwan Seo, Dongwon Lee
Ultrasonography is a reliable diagnostic modality for muscle and tendon injuries, but it has been challenging to find right diagnosis of minor musculoskeletal injuries by conventional ultrasonographic imaging. A large amount of hydrogen peroxide (H2O2) are known to be generated during tissue damages such as mechanical injury and therefore H2O2 holds great potential as a diagnostic and therapeutic marker for mechanical injuries in the musculoskeletal system. We previously developed poly(vanillyl alcohol-co-oxalate) (PVAX), which rapidly scavenges H2O2 and exerts antioxidant and anti-inflammatory activity in H2O2-associated diseases...
2017: Theranostics
https://www.readbyqxmd.com/read/28743830/role-of-melatonin-combined-with-exercise-as-a-switch-like-regulator-for-circadian-behavior-in-advanced-osteoarthritic-knee
#18
Yunkyung Hong, Hyunsoo Kim, Seunghoon Lee, Yunho Jin, Jeonghyun Choi, Sang-Rae Lee, Kyu-Tae Chang, Yonggeun Hong
Here, we show the role of melatonin combined with or without exercise as a determinant of multicellular behavior in osteoarthritis. We address the relationship between the molecular components governing local circadian clock and changes in the osteoarthritic musculoskeletal axis. Melatonin was injected subcutaneously in animals with advanced knee osteoarthritis (OA) for 4 weeks. Concurrently, moderate treadmill exercise was applied for 30 min/day. Morphometric, histological, and gene/protein-level analyses were performed in the cartilage, synovium, bone, and gastrocnemius muscle...
July 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28727716/the-relationship-between-body-mass-index-and-fluoroscopy-time-during-intraarticular-hip-injection-a-multicenter-cohort-study
#19
Zachary L McCormick, Meghan Bhave, David T Lee, Paul Scholten, Samuel K Chu, Ashwin N Babu, Mary Caldwell, Craig Ziegler, Humaira Ashraf, Ryan Clark, Claire Gross, Jeffrey Cara, Kristen McCormick, Brendon Ross, Joel Press, David R Walega, Daniel Cushman
BACKGROUND: Higher body mass index (BMI) is associated with difficulty in obtaining imaging studies. While there is a small body of literature regarding the relationship between fluoroscopy time and BMI during injections for pain management, this has not been studied for intraarticular (IA) hip injections. Further, in academic training centers, trainee involvement may affect this relationship. OBJECTIVE: To determine the relationship between BMI and fluoroscopy time during IA hip injections, both with and without involvement of a trainee...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28727705/activation-of-the-rage-stat3-pathway-in-the-dorsal-root-ganglion-contributes-to-the-persistent-pain-hypersensitivity-induced-by-lumbar-disc-herniation
#20
Xin-Sheng Zhang, Xiao Li, Hai-Jie Luo, Zhu-Xi Huang, Cui-Cui Liu, Qing Wan, Shu-Wei Xu, Shao-Ling Wu, Song-Jian Ke, Chao Ma
BACKGROUND: Clinically, chronic low back pain and sciatica associated with lumbar disc herniation (LDH) is a common musculoskeletal disorder. Due to the unawareness of detailed mechanisms, it is difficult to get an effective therapy. OBJECTIVE: The aim of the present study was to identify the role of the RAGE/STAT3 pathway in the dorsal root ganglion (DRG) on the formation and development of persistent pain hypersensitivity induced by LDH. STUDY DESIGN: Controlled animal study...
July 2017: Pain Physician
keyword
keyword
109643
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"