Jean-Antoine Ribeil, Myriam Labopin, Aurélie Stanislas, Benjamin Deloison, Delphine Lemercier, Anoosha Habibi, Souha Albinni, Caroline Charlier, Olivier Lortholary, François Lefrere, Mariane De Montalembert, Stéphane Blanche, Frédéric Galactéros, Jean-Marc Tréluyer, Eliane Gluckman, Yves Ville, Laure Joseph, Delville Marianne, Alexandra Benachi, Marina Cavazzana
Sickle cell disease (SCD) in pregnancy can be associated with adverse maternal and perinatal outcomes. Furthermore, complications of SCD can be aggravated by pregnancy. Optimal prenatal care aims to decrease the occurrence of maternal and fetal complications. A retrospective, French, two-center study compared two care strategies for pregnant women with SCD over two time periods. In the first study period (2005-2010), the women were systematically offered prophylactic transfusions. In the second study period (2011-2014), a targeted transfusion strategy was applied whenever possible, and home-based prophylactic nocturnal oxygen therapy was offered to all the pregnant women...
March 30, 2018: American Journal of Hematology