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adverse obstetric outcome

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https://www.readbyqxmd.com/read/28541800/incidence-of-superimposed-preeclampsia-among-pregnant-asian-women-with-chronic-hypertension
#1
Dittakarn Boriboonhirunsarn, Apichaya Pradyachaipimol, Boonlert Viriyapak
OBJECTIVE: To determine the incidence and associated factors of superimposed preeclampsia among pregnant women with chronic hypertension. METHODS: A total of 300 pregnant women diagnosed with chronic hypertension were reviewed. Data were retrieved from medical records, including obstetric data, characteristics of hypertension, and pregnancy outcomes. Incidence of superimposed preeclampsia was estimated. Various characteristics were compared to determine associated risk factors...
May 25, 2017: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/28522320/risks-and-consequences-of-puerperal-uterine-inversion-in-the-united-states-2004-2013
#2
Sarah L Coad, Leanne S Dahlgren, Jennifer A Hutcheon
BACKGROUND: Puerperal uterine inversion is a rare, potentially life-threatening obstetrical emergency. The current literature consists of small case series and a single nationwide study from Europe with only 15 cases. OBJECTIVE: We aimed to define the incidence, temporal trends and outcomes in women with uterine inversion using a nationally representative United States (US) cohort. STUDY DESIGN: We used the Nationwide Inpatient Sample, a 20% sample of US hospital admissions, to identify all deliveries from 2004 to 2013...
May 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28522033/placenta-directed-gene-therapy-for-fetal-growth-restriction
#3
REVIEW
Tara Krishnan, Anna L David
Fetal growth restriction (FGR) is a serious pregnancy complication affecting ∼8% of all pregnancies. There is no treatment to increase fetal growth in the uterus. Gene therapy presents a promising treatment strategy for FGR, with the use of adenoviral vectors encoding for proteins such as vascular endothelial growth factor (VEGF) and insulin-like growth factor demonstrating improvements in fetal growth, placental function, and neonatal outcome in preclinical studies. Safety assessments suggest no adverse risk to the mother or fetus for VEGF maternal gene therapy; a clinical trial is in development...
May 15, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28513120/gestational-weight-gain-and-its-relationship-with-maternal-characteristics
#4
Yeela Borenstein Ben Naftali, Ido Solt, Lior Lowenstein, Irit Chermesh
BACKGROUND: Both high and insufficient weight gain during pregnancy have been associated with adverse outcomes for mothers and their offspring. OBJECTIVES: To describe self-reported weight gain during pregnancy, assess the concurrence of this weight gain with issued recommendations, and investigate associations between lifestyle factors and weight gain. METHODS: In this cross-sectional study, 109 pregnant women hospitalized in one gynecological and obstetrics department completed questionnaires related to weight gain and lifestyle factors such as smoking, diet and exercise...
May 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28512745/implementation-of-multi-disciplinary-care-reduces-maternal-mortality-in-women-with-sickle-cell-disease-living-in-low-resource-setting
#5
Eugenia Vicky Asare, Edeghonghon Olayemi, Theodore Boafor, Yvonne Dei-Adomakoh, Enoch Mensah, Harriet Ghansah, Yvonne Osei-Bonsu, Selina Crabbe, Latif Musah, Charles Hayfron-Benjamin, Brittany Covert, Adetola A Kassim, Andra James, Mark Rodeghier, Michael R DeBaun, Samuel A Oppong
Sickle cell disease (SCD) is associated with adverse pregnancy outcome. In women with SCD living in low-resource settings, pregnancy is associated with significantly increased maternal and perinatal mortality rates. We tested the hypothesis that implementing a multidisciplinary obstetric and hematology care team in a low-resource setting would significantly reduce maternal and perinatal mortality rates. We conducted a before-and-after study, at the Korle-Bu Teaching Hospital in Accra, Ghana, to evaluate the effect of a multidisciplinary obstetric-hematology care team for women with SCD in a combined SCD-Obstetric Clinic...
May 16, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28511050/maternal-distress-in-late-pregnancy-alters-obstetric-outcomes-and-the-expression-of-genes-important-for-placental-glucocorticoid-signalling
#6
Katie L Togher, Eimear Treacy, Gerard W O'Keeffe, Louise C Kenny
The experience of maternal distress in pregnancy is often linked with poorer obstetric outcomes for women as well as adverse outcomes for offspring. Alterations in placental glucocorticoid signalling and subsequent increased fetal exposure to cortisol have been suggested to underlie this relationship. In the current study, 121 pregnant women completed the Perceived Stress Scale, State Trait Anxiety Inventory and Edinburgh Postnatal Depression Scale in the third trimester of pregnancy. Placental samples were collected after delivery...
May 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28506952/retrospective-evaluation-of-pregnant-women-with-celiac-disease
#7
Kemal Beksaç, Gökçen Örgül, Murat Çağan, Ergun Karaağaoğlu, Serap Arslan, Mehmet Sinan Beksaç
OBJECTIVE: To show celiac disease (CD) and its poor pregnancy outcome relationship, and to demonstrate the importance of a gluten-free diet together with low-dose low-molecular-weight heparin (LMWH) and low-dose corticosteroid (LDC) in the management of pregnancies with CD. MATERIAL AND METHODS: This study consisted of 2 groups of patients. Six patients with CD (control group) on a gluten-free diet were monitored during their first pregnancies within the framework of antenatal care program and their pregnancy outcomes were compared with eight poorly-treated pregnant patients with CD (study group) who were referred from other medical institutions...
March 15, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28494268/pregnancy-outcome-and-cord-blood-cotinine-level-a-cross-sectional-comparative-study-between-secondhand-smokers-and-non-secondhand-smokers
#8
B Abdullah, B Muadz, M N Norizal, N Ismail, N K Kornain, M Kutty
OBJECTIVE: To compare the pregnancy outcome and cord blood cotinine levels between secondhand smokers and non-secondhand smokers. STUDY DESIGN: This was a cross-sectional comparative study in a Malaysian tertiary obstetric hospital involving 200 non-smoking pregnant women at term, of whom 100 were secondhand smokers and 100 were non-secondhand smokers. Those with multiple pregnancies, with a body mass index (BMI) of more than 30kg/m(2) or who delivered by Caesarean section were excluded...
May 3, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28491128/non-communicable-diseases-during-pregnancy-in-low-and-middle-income-countries
#9
Julia Hussein
Apart from the risks of obstetric complications like haemorrhage and eclampsia, a large number of medical conditions affect pregnancy and result in adverse outcomes for both the mother and offspring. Non-communicable diseases in pregnancy are becoming increasingly important in contributing to death and poor health. Changes in the patterns and distribution of these conditions mean that we need new perspectives and ways of dealing with these challenges for the future. This article reviews the burden of ill-health due to non-communicable diseases during pregnancy in low and middle income countries and presents some paradigms relevant to public health and health system needs of the future...
March 2017: Obstetric Medicine
https://www.readbyqxmd.com/read/28489924/neonatal-and-maternal-outcomes-of-successful-manual-rotation-to-correct-malposition-of-the-fetal-head-a-retrospective-and-prospective-observational-study
#10
Nicola Tempest, Naomi McGuinness, Steven Lane, Dharani K Hapangama
OBJECTIVE: To evaluate the neonatal and maternal outcomes associated with successful operative vaginal births assisted by manual rotation. DESIGN: Prospective and retrospective observational study. SETTING: Delivery suite in a tertiary referral teaching hospital in England. POPULATION: A cohort of 2,426 consecutive operative births, in the second stage of labour, complicated with malposition of the fetal head during 2006-2013...
2017: PloS One
https://www.readbyqxmd.com/read/28487015/macroscopic-and-microscopic-morphology-of-first-trimester-miscarriage-and-subsequent-pregnancy-outcome-an-exploratory-study
#11
Isabelle M A van Gruting, Moira A Müller, Krijn van Groningen, Niek Exalto
INTRODUCTION: Reduced chorionic villous vascularization is associated with first trimester miscarriage and second trimester fetal loss. Differences in villous vascularization have been observed in combination with complications in the third trimester of pregnancy. The aim of this study was to investigate whether abnormal morphology and reduced chorionic villous vascularization in first trimester miscarriages are associated with an increased risk on adverse outcome and/or pregnancy complications in subsequent pregnancy...
May 2017: Placenta
https://www.readbyqxmd.com/read/28486373/medical-and-obstetric-complications-among-pregnant-women-with-liver-cirrhosis
#12
Anna Palatnik, Mary E Rinella
OBJECTIVE: To evaluate clinical characteristics and obstetric outcomes in pregnant women with liver cirrhosis. METHODS: This was a retrospective matched cohort study of women with liver cirrhosis between January 2005 and January 2016 in a university hospital. Women in a case group were matched to women in a control group according to year of delivery, age, body mass index, and parity in a 1:4 ratio. Bivariable and multivariable analyses were performed to compare the prevalence of the primary composite outcome, which included any one of the following: fetal or neonatal demise, placental abruption, preeclampsia, preterm delivery at less than 37 weeks of gestation, and small-for-gestational age neonate between women in the case group and those in the control group...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28485783/influence-of-screening-and-intervention-of-hyperthyroidism-on-pregnancy-outcome
#13
Y Wang, X-L Sun, C-L Wang, H-Y Zhang
OBJECTIVE: To discuss the influence of screening and intervention of hyperthyroidism on pregnancy outcome. PATIENTS AND METHODS: The clinical data of 122 pregnant women who had been confirmed with hyperthyroidism from April 2012 to July 2014 in the Weifang People's Hospital were analyzed retrospectively (25 untreated, 97 treated). 60 with normal pregnancy check were randomly selected as control group. The pregnancy outcomes of the two groups of patients were analyzed...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28484356/associations-of-body-mass-index-and-gestational-weight-gain-with-term-pregnancy-outcomes
#14
Tatjana Barisic, Vjekoslav Mandic, Ivana Barac
INTRODUCTION: Obesity is one of the greatest health problems in the world. The World Health Organization (WHO) defined obesity as a disease in which the excess of adipose tissue accumulates in such a degree that is endangers health. Obesity is a very complex multifactor disease that is developed under the influence of genetic and metabolic factors, environment, social and cultural environment as well as bad habits. The causes of obesity can be numerous. The most common source of obesity is the development of energetic imbalance...
March 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28483805/treating-the-dysfunctional-placenta
#15
Colin Peter Sibley
Placental dysfunction underlies major obstetric diseases such as pre-eclampsia and fetal growth restriction (FGR). Whilst there has been a little progress in prophylaxis there are still no treatments for placental dysfunction in normal obstetric practice. However, a combination of increasingly well described in vitro systems for studying the human placenta, together with the availability of more appropriate animal models of pre-eclampsia and FGR, has facilitated a recent surge in work aimed at repurposing drugs and therapies, developed for other conditions, as treatments for placental dysfunction...
May 8, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28476691/oxytocin-administration-during-spontaneous-labor-guidelines-for-clinical-practice-guidelines-short-text
#16
C Dupont, M Carayol, C Le Ray, C Deneux-Tharaux, D Riethmuller
No abstract text is available yet for this article.
May 2, 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28473516/is-vaginal-breech-delivery-associated-with-higher-risk-for-perinatal-death-and-cerebral-palsy-compared-with-vaginal-cephalic-birth-registry-based-cohort-study-in-norway
#17
Solveig Bjellmo, Guro L Andersen, Marit Petra Martinussen, Pål Richard Romundstad, Sissel Hjelle, Dag Moster, Torstein Vik
OBJECTIVE: This paper aims to study if vaginal breech delivery is associated with increased risk for neonatal mortality (NNM) or cerebral palsy (CP) in Norway where vaginal delivery accounts for 1/3 of all breech deliveries. DESIGN: Cohort study using information from the national Medical BirthRegister and Cerebral Palsy Register. SETTING: Births in Norway 1999-2009. PARTICIPANTS: 520 047 term-born singletons without congenital malformations...
May 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28467228/dental-health-dispositions-of-pregnant-women-a-survey-from-a-hospital-clinic-in-istanbul
#18
Ayse Filiz Gokmen Karasu, Nukhet Kutuk, Serdar Aydin, Ilknur Adanir, Seda Ates, Neslihan Bademler
Dental hygienic habits should be maintained in pregnancy despite challenges. We aimed to study the dental attitudes and habits of pregnant women. The patients attending our hospital clinic were invited to fill out a structured questionnaire categorised into three major domains: (1) general oral hygiene status, (2) dental habits, and (3) dental attandence both during pregnancy and prior to pregnancy. Four hundred and seventy four women agreed to participate. Mean age of participants was 28 (18-43). While 184 (38%) women reported brushing twice a day, only 98 (20%) women claimed using floss and or mouth rinse...
May 3, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28464913/prevalence-of-hyperglycaemia-first-detected-during-pregnancy-and-subsequent-obstetric-outcomes-at-st-francis-hospital-nsambya
#19
Betty Nakabuye, Silver Bahendeka, Romano Byaruhanga
BACKGROUND: Women with hyperglycaemia detected during pregnancy are at greater risk for adverse pregnancy outcomes. Data on hyperglycaemia in pregnancy in sub-Saharan Africa is scanty and varied depending on the populations studied and the methodologies used to define hyperglycaemia in pregnancy. With the recent 2013 World Health Organisation (WHO) diagnostic criteria and classification, there is yet no sufficient data on the prevalence of hyperglycaemia in sub-Saharan Africa. The objective was to determine the prevalence of Hyperglycaemia first detected during pregnancy and subsequent obstetric outcomes among patients attending antenatal care (ANC) at St...
May 2, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28464238/ondansetron-for-neuraxial-morphine-induced-pruritus-a-meta-analysis-of-randomized-controlled-trials
#20
REVIEW
W Wang, L Zhou, L Sun
WHAT IS KNOWN AND OBJECTIVE: Pruritus is one of the most common adverse effects associated with neuraxial morphine. Ondansetron has been used to deal with the problem of neuraxial morphine-induced pruritus (NMIP). The aim of this meta-analysis was to evaluate the preventive efficacy of ondansetron on NMIP. METHODS: Online databases such as PubMed, EMBASE and the Cochrane Central Register of Controlled Trials were searched for eligible randomized controlled trials (RCTs)...
May 2, 2017: Journal of Clinical Pharmacy and Therapeutics
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