keyword
MENU ▼
Read by QxMD icon Read
search

Mid trimester

keyword
https://www.readbyqxmd.com/read/29316516/polybrominated-diphenyl-ethers-pbdes-and-hydroxylated-pbde-metabolites-oh-pbdes-in-maternal-and-fetal-tissues-and-associations-with-fetal-cytochrome-p450-gene-expression
#1
Ami R Zota, Susanna D Mitro, Joshua F Robinson, Emily G Hamilton, June-Soo Park, Emily Parry, R Thomas Zoeller, Tracey J Woodruff
BACKGROUND: Human fetal exposures to polybrominated diphenyl ethers (PBDEs) and their metabolites (OH-PBDEs) are unique from adults, and in combination with a different metabolic profile, may make fetal development more sensitive to adverse health outcomes from these exposures. However, we lack data to characterize human fetal PBDE exposures and the metabolic factors that can influence these exposures. OBJECTIVE: We examined differences between 2nd trimester maternal and fetal exposures to PBDEs and OH-PBDEs...
January 6, 2018: Environment International
https://www.readbyqxmd.com/read/29236171/uterine%C3%A2-fibroid-size-modifications-during-pregnancy-and-puerperium-evidence-from-the-first-systematic-review-of-literature
#2
REVIEW
Amerigo Vitagliano, Marco Noventa, Attilio Di Spiezio Sardo, Gabriele Saccone, Salvatore Gizzo, Shara Borgato, Salvatore Giovannni Vitale, Antonio Simone Laganà, Giovanni Battista Nardelli, Pietro Salvatore Litta, Carlo Saccardi
PURPOSE: The influence of pregnancy on uterine fibroid size still remains an unsolved dilemma. Basing on current knowledge, physicians are not able to inform patients about the likelihood of uterine fibroids to modify their size during pregnancy. Study aim was to summarize available evidence concerning the size modifications of uterine fibroids during each trimester of pregnancy and during puerperium. METHODS: The review was reported following the PRISMA guidelines and registered in PROSPERO (registration number: CRD42017071117)...
December 13, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29219619/prenatal-and-early-life-fructose-fructose-containing-beverages-and-mid-childhood-asthma
#3
Lakiea S Wright, Sheryl L Rifas-Shiman, Emily Oken, Augusto A Litonjua, Diane R Gold
RATIONALE: Cross-sectional studies have linked intake of high fructose corn syrup sweetened beverages with asthma in school children. OBJECTIVE: To examine associations of maternal prenatal and early childhood intake of sugar sweetened beverages and fructose with current asthma in mid-childhood (median 7.7years). METHODS: We assessed maternal pregnancy (1st and 2nd trimester average) and child (median 3.3years) intake of sugar sweetened beverages and total fructose using food frequency questionnaires in 1068 mother-child pairs from Project Viva, a prospective pre-birth cohort...
December 8, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29197487/no-352-technical-update-the-role-of-early-comprehensive-fetal-anatomy-ultrasound-examination
#4
Ori Nevo, Richard Brown, Phyllis Glanc, Ken Lim
OBJECTIVE: This guideline presents an evidence-based technical update and recommendations for the performance of early comprehensive fetal anatomic scanning (ECFAS) at 11 to 16 weeks' gestation. OPTIONS: Patients at high risk for fetal anomalies and in whom traditional mid-second trimester transabdominal imaging may be challenging or who may benefit from earlier identification of fetal anomalies may be suitable for early fetal anatomy scanning. OUTCOMES: This practice may result in earlier identification of fetal anomalies and provide earlier intervention options in high-risk populations and/or in populations where mid-second trimester transabdominal scanning is challenging...
December 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29186303/maternal-and-neonatal-vitamin-d-status-are-not-associated-with-risk-of-childhood-type-1-diabetes-a-scandinavian-case-cohort-study
#5
Steffen U Thorsen, Karl Mårild, Sjurdur F Olsen, Klaus K Holst, German Tapia, Charlotta Granström, Thorhallur I Halldorsson, Arieh S Cohen, Margaretha Haugen, Marika Lundqvist, Torild Skrivarhaug, Pål R Njølstad, Geir Joner, Per Magnus, Ketil Størdal, Jannet Svensson, Lars C Stene
Studies on vitamin D status during pregnancy and risk of type 1 diabetes (T1D) lack consistency, and are limited by small sample sizes or single measures of 25-hydroxyvitamin D (25(OH)D). We investigated whether average maternal 25(OH)D plasma concentrations during pregnancy are associated with risk of childhood T1D. In a case-cohort design, we identified 459 children with T1D and a random sample (n = 1,561) from the Danish National Birth Cohort (n = 97,127) and Norwegian Mother and Child Cohort Study (n = 113,053)...
November 23, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29170495/first-trimester-vaginal-microbiome-diversity-a-potential-indicator-of-preterm-delivery-risk
#6
Mohammed Monzoorul Haque, Mitali Merchant, Pinna Nishal Kumar, Anirban Dutta, Sharmila S Mande
Preterm birth is a leading cause of global neonate mortality. Hospitalization costs associated with preterm deliveries present a huge economic burden. Existing physical/biochemical markers for predicting preterm birth risk are mostly suited for application at mid/late pregnancy stages, thereby leaving very short time (between diagnosis and delivery) for adopting appropriate intervention strategies. Recent studies indicating correlations between pre/full-term delivery and the composition of vaginal microbiota in pregnant women have opened new diagnostic possibilities...
November 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29168294/association-of-prenatal-folate-status-with-early-childhood-wheeze-and-atopic-dermatitis
#7
Aditi Roy, Mehmet Kocak, Terryl J Hartman, Shanda Vereen, Margaret Adgent, Chandrika Piyathilake, Frances A Tylavsky, Kecia N Carroll
BACKGROUND: Prenatal folic acid supplementation is recommended to prevent birth defects. Some foods are fortified in the U.S.to ensure sufficient intake among reproductive-aged women. However, high prenatal folate exposure may be a risk factor for childhood atopic diseases. We investigated associations between prenatal folate and early childhood wheeze and atopic dermatitis in a U.S. cohort. METHODS: We studied 858 mother-child dyads, enrolled prenatally. Folate was measured in 2(nd) and 3(rd) trimester maternal plasma...
November 23, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29153670/protocol-for-measurement-of-mean-arterial-pressure-at-10-40weeks-gestation
#8
Llinos Roberts, Piya Chaemsaithong, Daljit S Sahota, Kypros H Nicolaides, Liona C Y Poon
The study aimed to identify the simplest protocol for the measurement of mean arterial pressure (MAP) across 10-40weeks' gestation. 2726 women with uncomplicated singleton pregnancy attending for their routine hospital visit between 10 and 40weeks' gestation were recruited prospectively. The blood pressure (BP) was measured according to the National Heart Foundation of Australia (NHFA) protocol using automated devices. Linearizing regression models were determined for MAP derived from single, repeat and average measurements taken in the left and right arms using the same polynomial power of the best fit model determined using the NHFA protocol...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29131362/sex-discordance-identification-following-non-invasive-prenatal-testing
#9
Ebony J Richardson, Fergus P Scott, Andrew C McLennan
OBJECTIVE: To characterize genotype-phenotype discordance identified in the routine clinical setting, and explore the associated diagnostic and counseling challenges. METHOD: Cases were derived from a cohort of pregnant women who attended a multi-site specialist prenatal screening and ultrasound service for non-invasive prenatal testing by cell-free DNA analysis and mid-trimester fetal morphology assessment. RESULTS: Seven cases of genotype-phenotype discordance were identified from a cohort of 12,919 women between June 2013 - March 2017 (incidence 1/1845 pregnancies)...
November 13, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29111424/abnormal-mid-trimester-cardiac-strain-in-women-with-chronic-hypertension-predates-superimposed-preeclampsia
#10
Sajid Shahul, Hadi Ramadan, Ariel Mueller, Junaid Nizamuddin, Rabab Nasim, Joana Lopes Perdigao, Sireesha Chinthala, Avery Tung, Sarosh Rana
BACKGROUND: Chronic hypertension (cHTN) affects 7% of all pregnancies. We hypothesized that cHTN during pregnancy would be associated with abnormal myocardial strain patterns and adverse perinatal outcomes. METHODS: This was a retrospective cohort study of patients seen in a high-risk obstetrics clinic with cHTN. Parturients with a singleton pregnancy who had undergone an echocardiogram as part of routine clinical care were eligible. Clinical and demographic information was collected from medical records...
October 23, 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29106643/zika-virus-replicates-in-proliferating-cells-in-explants-from-first-trimester-human-placentas-potential-sites-for-dissemination-of-infection
#11
Takako Tabata, Matthew Petitt, Henry Puerta-Guardo, Daniela Michlmayr, Eva Harris, Lenore Pereira
Background: Maternal Zika virus (ZIKV) infection with prolonged viremia leads to fetal infection and congenital Zika syndrome. We reported that ZIKV infects primary cells from human placentas and fetal membranes. Here, we studied viral replication in numerous explants of anchoring villi and basal decidua from first-trimester human placentas and mid-gestation amniotic epithelial cells (AmEpCs). Methods: Explants and AmEpCs were infected with American and African ZIKV strains at low multiplicities, and ZIKV proteins were visualized by immunofluorescence...
November 2, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29060631/automatic-measurement-of-fetal-nuchal-translucency-from-three-dimensional-ultrasound-data
#12
Siqing Nie, Jinhua Yu, Ping Chen, Yuanyuan Wang, Yi Guo, Jian Qiu Zhang
The Nuchal translucency (NT), which is the collection of fluid at the back of the fetal neck, is related to chromosomal defects and early cardiac failure in first trimester of pregnancy. In clinic, the thickness of NT is used as an important marker in prenatal screening, and is manually measured by sonographers in the mid-sagittal plane. In this paper, an automatic method based on dynamic programming is proposed to detect the thickness and area of NT in the mid-sagittal plane. Furthermore, the volume of NT in the whole three-dimensional ultrasound data is also measured...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060332/investigating-fetal-myocardial-function-in-heart-anomalies-by-doppler-myocardial-performance-indices
#13
Ahsan H Khandoker, Haitham M Al-Angari, F Marzbanrad, Y Kimura
Fetal myocardial performance index are used to assess aspects of systolic and diastolic function in developing fetal heart. The aim of this study was to determine normal values of fetal left ventricular (LV) Tei Index (TI) for measuring systolic performance and K-Index (KI) for diastolic performance in early (<;32 weeks), Mid (32-35 weeks) and late trimester (35-41 weeks) normal fetuses and fetuses with congenital heart diseases (CHD). Simultaneous recordings of Doppler Ultrasound Signal (DUS) of the LV outflow tracts and fetal electrocardiogram signals were obtained in 57 normal and 14 fetuses with CHD...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29055173/safety-and-efficacy-of-the-cervical-pessary-combined-with-vaginal-progesterone-for-the-prevention-of-spontaneous-preterm-birth
#14
Georgios Daskalakis, Dimitrios Zacharakis, Marianna Theodora, Panagiotis Antsaklis, Nikolaos Papantoniou, Dimitris Loutradis, Aris Antsaklis
INTRODUCTION: The aim of this study was to evaluate the safety and efficacy of the combined treatment of cervical pessary and endovaginal progesterone for the prevention of spontaneous preterm birth (SPB) in women with a short cervical length (CL) between 20 and 24 weeks of gestation. MATERIALS AND METHODS: This is a prospective study of women with a singleton pregnancy and a sonographically detected mid-trimester CL ≤25 mm. The primary outcome measure was spontaneous delivery before 34 weeks (238 days) of gestation...
October 21, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29026216/associations-of-maternal-and-cord-blood-adipokines-with-offspring-adiposity-in-project-viva-is-there-an-interaction-with-child-age
#15
L-J Li, S L Rifas-Shiman, I M Aris, J G Young, C Mantzoros, M-F Hivert, E Oken
OBJECTIVES: Higher leptin and lower adiponectin correlate with adult and childhood adiposity, but it is unclear how exposure to these adipokines during gestation relates to offspring growth. We aimed to investigate the relationships of maternal and cord adipokines with offspring adiposity across childhood to early adolescence, as well as interactions with child age. METHODS: In mother-child pairs in the Project Viva cohort, we measured adipokines in mothers at 2nd trimester (n=1106) and in cord blood at birth (n=657)...
October 13, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29023931/evaluation-of-the-right-and-left-ventricles-an-integrated-approach-measuring-the-area-length-and-width-of-the-chambers-in-normal-fetuses
#16
Greggory R DeVore, Berthold Klas, Gary Satou, Mark Sklansky
INTRODUCTION: The purpose of this study was to simultaneously measure with speckle tracking software the end-diastolic ventricular area (A), basal transverse width (BW), mid-chamber transverse width (MW), and basal-apical length (BAL) in normal fetuses and those with pathology. METHODS: The 4-chamber view of the fetal heart was obtained in 200 control fetuses between 20 and 40 weeks of gestation and in 9 third-trimester fetuses with heart malformations. The mean and standard deviation for the A, BW, MW, and BAL were computed from the control fetuses and Z scores computed from the 9 fetuses with cardiac malformations...
December 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28975446/determinants-of-preeclampsia-in-women-with-type-1-diabetes
#17
Paweł Gutaj, Agnieszka Zawiejska, Urszula Mantaj, Ewa Wender-Ożegowska
AIMS: Despite improvement in diabetic care over the years, the incidence of hypertensive disorders of pregnancy is still very high. Therefore, the aim of our study was to determine risk factors for PE in women with T1DM. METHODS: This study was a prospective, nested case-control study on a population of 165 women with T1DM. Women were divided into 3 subgroups: normotensive (N = 141), gestational hypertension (GH) (N = 8), and PE (N = 16). Clinical data were collected in the first trimester (< 12th week), in mid-pregnancy (20-24th weeks), and just prior to delivery (34-39th weeks)...
December 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28966619/changes-in-t-cell-and-dendritic-cell-phenotype-from-mid-to-late-pregnancy-are-indicative-of-a-shift-from-immune-tolerance-to-immune-activation
#18
Nishel Mohan Shah, Anna A Herasimtschuk, Adriano Boasso, Adel Benlahrech, Dietmar Fuchs, Nesrina Imami, Mark R Johnson
During pregnancy, the mother allows the immunologically distinct fetoplacental unit to develop and grow. Opinions are divided as to whether this represents a state of fetal-specific tolerance or of a generalized suppression of the maternal immune system. We hypothesized that antigen-specific T cell responses are modulated by an inhibitory T cell phenotype and modified dendritic cell (DC) phenotype in a gestation-dependent manner. We analyzed changes in surface markers of peripheral blood T cells, ex vivo antigen-specific T cell responses, indoleamine 2,3-dioxygenase (IDO) activity (kynurenine/tryptophan ratio, KTR), plasma neopterin concentration, and the in vitro expression of progesterone-induced blocking factor (PIBF) in response to peripheral blood mononuclear cell culture with progesterone...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28935154/inducible-knockout-of-syncytin-a-gene-leads-to-an-extensive-placental-vasculature-deficiency-implications-for-preeclampsia
#19
Shan Qiao, Fengchao Wang, Haibin Chen, Shi-Wen Jiang
Syncytin-1, a human endogenous retroviral envelope gene (HERVW1), is specifically expressed in placental trophoblasts and mediates the formation of syncytiotrophoblasts through a fusogenic activity. Syncytin-1 expression deficiency has been repeatedly observed in preeclamptic/IUGR placentas. Previous gene knockout studies indicated that in mice, complete syncytin-A null mouse embryos died in utero between 11.5 and 13.5days of gestation. However, the complete knockout model could not fully recapitulate the mid- to third-trimester, time-specific syncytin-1 deficiency in preeclampsia patients...
November 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28931691/vertical-transmission-of-hepatitis-c-virus-variable-transmission-bottleneck-and-evidence-of-midgestation-in-utero-infection
#20
Sébastien Fauteux-Daniel, Ariane Larouche, Virginie Calderon, Jonathan Boulais, Chanel Béland, Doris G Ransy, Marc Boucher, Valérie Lamarre, Normand Lapointe, Isabelle Boucoiran, Armelle Le Campion, Hugo Soudeyns
Hepatitis C virus (HCV) can be transmitted from mother to child during pregnancy and childbirth. However, the timing and precise biological mechanisms that are involved in this process are incompletely understood, as are the determinants that influence transmission of particular HCV variants. Here we report results of a longitudinal assessment of HCV quasispecies diversity and composition in 5 cases of vertical HCV transmission, including 3 women coinfected with human immunodeficiency virus type 1 (HIV-1). The population structure of HCV variant spectra based on E2 envelope gene sequences (nucleotide positions 1491 to 1787), including hypervariable regions 1 and 2, was characterized using next-generation sequencing and median-joining network analysis...
December 1, 2017: Journal of Virology
keyword
keyword
109637
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"