Federico Alberici, Elisa Delbarba, Chiara Manenti, Laura Econimo, Francesca Valerio, Alessandra Pola, Camilla Maffei, Stefano Possenti, Simone Piva, Nicola Latronico, Emanuele Focà, Francesco Castelli, Paola Gaggia, Ezio Movilli, Sergio Bove, Fabio Malberti, Marco Farina, Martina Bracchi, Ester Maria Costantino, Nicola Bossini, Mario Gaggiotti, Francesco Scolari
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus disease (COVID-19), is a major pandemic challenging health care systems around the world. The optimal management of patients infected with COVID-19 is still unclear, although the consensus is moving toward the need of a biphasic approach. During the first phase of the disease (from onset of the symptoms up to 7-10 days) viral-induced effects are prominent, with the opportunity to institute antiviral therapy. In the second inflammatory phase of the disease, immunosuppressive strategies (for example with glucocorticoids or anticytokine drugs) may be considered...
May 2020: KI Reports