Marat Fudim, Nicolas Ashur, Aaron D Jones, Andrew P Ambrosy, Bradley A Bart, Javed Butler, Horng H Chen, Stephen J Greene, Yogesh Reddy, Margaret M Redfield, Abhinav Sharma, Adrian F Hernandez, Gary Michael Felker, Barry A Borlaug, Robert J Mentz
AIMS: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition, and tissue congestion manifested by oedema is not present in all patients. We compared clinical characteristics, exercise capacity, and outcomes in patients with HFpEF with and without oedema. METHODS AND RESULTS: This study was a post hoc analysis of pooled data of patients with left ventricular ejection fraction of ≥50% enrolled in the DOSE, CARRESS-HF, RELAX, ATHENA, ROSE, INDIE, and NEAT trials...
February 2021: ESC Heart Failure