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https://www.readbyqxmd.com/read/29791029/development-of-a-3d-ultrasound-guidance-system-for-permanent-breast-seed-implantation
#1
Justin Michael, Daniel Morton, Deidre Batchelar, Michelle Hilts, Juanita Crook, Aaron Fenster
PURPOSE: Permanent breast seed implantation (PBSI) is a promising radiotherapy technique for early-stage breast cancer, completed in a single visit by permanently implanting 103 Pd seeds using needles inserted through a template and guided by 2D ultrasound (US). However, operator dependence has been highlighted as a limitation of this procedure. Consequently, we propose and have developed an intraoperative guidance system using 3D US and an instrumented mechanical arm to provide intraoperative 3D imaging and needle template tracking...
May 23, 2018: Medical Physics
https://www.readbyqxmd.com/read/29785834/development-of-a-robust-mri-fiducial-system-for-automated-fusion-of-mr-us-abdominal-images
#2
Christopher P Favazza, Krzysztof R Gorny, Matthew R Callstrom, Anil N Kurup, Michael Washburn, Pamela S Trester, Charles L Fowler, Nicholas J Hangiandreou
We present the development of a two-component magnetic resonance (MR) fiducial system, that is, a fiducial marker device combined with an auto-segmentation algorithm, designed to be paired with existing ultrasound probe tracking and image fusion technology to automatically fuse MR and ultrasound (US) images. The fiducial device consisted of four ~6.4 mL cylindrical wells filled with 1 g/L copper sulfate solution. The algorithm was designed to automatically segment the device in clinical abdominal MR images...
May 21, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29774779/image-guided-radiation-therapy-for-post-operative-gynaecologic-cancer-patient-set-up-verification-with-and-without-implanted-fiducial-markers
#3
Donna H Murrell, Andrew Warner, Quinn Benwell, Wendy Wells, Danielle Scott, Vikram Velker, George Hajdok, David P D'Souza
BACKGROUND: Intensity modulated radiotherapy (IMRT) is increasingly being used to treat gynaecological malignancies in the postoperative setting. The purpose of this study was to evaluate the use of image-guided radiotherapy (IGRT) using cone-beam computed tomography (CBCT) with fiducial markers for daily localization. MATERIAL AND METHODS: A single institution study was performed of consecutive cervical or endometrial cancer patients receiving adjuvant external beam radiotherapy (n = 15)...
May 18, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29768185/a-simple-inexpensive-method-for-subcortical-stereotactic-targeting-in-nonhuman-primates
#4
J Nicole Bentley, Siri S S Khalsa, Michael Kobylarek, Karen E Schroeder, Kevin Chen, Ingrid L Bergin, Derek M Tat, Cynthia A Chestek, Parag G Patil
BACKGROUND: Many current neuroscience studies in large animal models have focused on recordings from cortical structures. While sufficient for analyzing sensorimotor systems, many processes are modulated by subcortical nuclei. Large animal models, such as nonhuman primates (NHP), provide an optimal model for studying these circuits, but the ability to target subcortical structures has been hampered by lack of a straightforward approach to targeting. NEW METHOD: Here we present a method of subcortical targeting in NHP that uses MRI-compatible titanium screws as fiducials...
May 13, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29765093/accurate-and-fiducial-marker-free-correction-for-three-dimensional-chromatic-shift-in-biological-fluorescence-microscopy
#5
Atsushi Matsuda, Lothar Schermelleh, Yasuhiro Hirano, Tokuko Haraguchi, Yasushi Hiraoka
Correction of chromatic shift is necessary for precise registration of multicolor fluorescence images of biological specimens. New emerging technologies in fluorescence microscopy with increasing spatial resolution and penetration depth have prompted the need for more accurate methods to correct chromatic aberration. However, the amount of chromatic shift of the region of interest in biological samples often deviates from the theoretical prediction because of unknown dispersion in the biological samples. To measure and correct chromatic shift in biological samples, we developed a quadrisection phase correlation approach to computationally calculate translation, rotation, and magnification from reference images...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29760592/4d-modeling-in-a-gimbaled-linear-accelerator-by-using-gold-anchor-markers
#6
Hideharu Miura, Shuichi Ozawa, Takaaki Matsuura, Atsushi Kawakubo, Fumika Hosono, Kiyoshi Yamada, Yasushi Nagata
Purpose: The purpose of this study was to verify whether the dynamic tumor tracking (DTT) feature of a Vero4DRT system performs with 10-mm-long and 0.28 mm diameter gold anchor markers. Methods: Gold anchor markers with a length of 10 mm and a diameter of 0.28 mm were used. Gold anchor markers were injected with short and long types into bolus material. These markers were sandwiched by a Tough Water (TW) phantom in the bolus material. For the investigation of 4-dimensional (4D) modeling feasibility under various phantom thicknesses, the TW phantom was added at 2 cm intervals (in upper and lower each by 1 cm)...
May 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29740971/target-position-reproducibility-in-left-breast-irradiation-with-deep-inspiration-breath-hold-using-multiple-optical-surface-control-points
#7
Aurora Fassi, Giovanni B Ivaldi, Paola Tabarelli de Fatis, Marco Liotta, Ilaria Meaglia, Patrizia Porcu, Lea Regolo, Marco Riboldi, Guido Baroni
The aim of this study was to investigate the use of 3D optical localization of multiple surface control points for deep inspiration breath-hold (DIBH) guidance in left-breast radiotherapy treatments. Ten left-breast cancer patients underwent whole-breast DIBH radiotherapy controlled by the Real-time Position Management (RPM) system. The reproducibility of the tumor bed (i.e., target) was assessed by the position of implanted clips, acquired through in-room kV imaging. Six to eight passive fiducials were positioned on the patients' thoraco-abdominal surface and localized intrafractionally by means of an infrared 3D optical tracking system...
May 8, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29730884/a-novel-integrated-quality-assurance-phantom-for-radiographic-and-non-radiographic-radiotherapy-localization-and-positioning-systems
#8
Amy S Yu, Tyler L Fowler, Piotr Dubrowski
PURPOSE: Various localization and positioning systems utilizing radiographic or non-radiographic methods have been developed to improve the accuracy of radiation treatment. Each quality assurance (QA) procedure requires its own phantom and is independent from each other, so the deviation between each system is unavailable. The purpose of this work is to develop and evaluate a single integrated QA phantom for different localization and positioning systems. METHODS: The integrated phantom was designed in 3D CAD software and 3D printed...
May 6, 2018: Medical Physics
https://www.readbyqxmd.com/read/29728517/a-first-in-man-study-of-68-ga-nanocolloid-pet-ct-sentinel-lymph-node-imaging-in-prostate-cancer-demonstrates-aberrant-lymphatic-drainage-pathways
#9
Jacki A Doughton, Michael S Hofman, Peter Eu, Rodney J Hicks, Scott G Williams
Purpose: To assess feasibility, safety and utility of a novel 68 Ga-nanocolloid radio-tracer with PET-CT lymphoscintigraphy for identification of sentinel lymph nodes (SLN). Methods: Pilot study of patients from a tertiary cancer hospital who required insertion of gold fiducials for prostate cancer radiation therapy. Participation did not affect cancer management. Ultrasound-guided transperineal intra-prostatic injection of PET tracer (iron oxide nanocolloid labelled with gallium-68) after placement of fiducials...
May 4, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29727310/rectal-culture-and-sensitivity-analysis-for-reducing-sepsis-risk-after-fiducial-marker-placement
#10
William M Mendenhall, Gail Sarto, Curtis M Bryant, Christopher G Morris, Christopher R Williams, Joseph A Costa, Mark Bandyk, Bradford S Hoppe, Randal H Henderson, R Charles Nichols, Nancy P Mendenhall
PURPOSE: Placement of fiducial markers for prostate radiotherapy (RT) is associated with a 2% to 3% risk of bacterial urinary tract infection (UTI) that may progress to sepsis necessitating hospitalization. These bacterial UTIs are primarily due to flouroquinolone (FQ) resistant Escherichia coli (E. coli). The incidence of this complication has increased in recent years. The purpose of this study is to determine whether rectal culture and sensitivity (C&S) to identify FQ resistant E...
May 4, 2018: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29707354/fiducial-marker-placement-for-stereotactic-body-radiation-therapy-via-convex-probe-endobronchial-ultrasound-a-case-series-and-review-of-literature
#11
REVIEW
Benjamin J Seides, John P Egan, Kim D French, Kevin L Kovitz, Neeraj R Desai
Convex probe endobronchial ultrasound (CP-EBUS) and stereotactic body radiotherapy (SBRT) are valuable tools in the diagnosis, staging, and treatment of thoracic malignancies. With widespread clinical adoption, novel uses of CP-EBUS beyond mediastinal diagnosis and staging continue to be discovered. SBRT is an attractive treatment strategy in early-stage lung cancer and oligo-metastatic disease of the chest when a surgical approach is either not feasible or desirable. Accurate application of SBRT is aided by the placement of radio-opaque fiducial markers (FM) to compensate for respiratory cycle movements...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29681676/tilted-light-sheet-microscopy-with-3d-point-spread-functions-for-single-molecule-super-resolution-imaging-in-mammalian-cells
#12
Anna-Karin Gustavsson, Petar N Petrov, Maurice Y Lee, Yoav Shechtman, W E Moerner
To obtain a complete picture of subcellular nanostructures, cells must be imaged with high resolution in all three dimensions (3D). Here, we present tilted light sheet microscopy with 3D point spread functions (TILT3D), an imaging platform that combines a novel, tilted light sheet illumination strategy with engineered long axial range point spread functions (PSFs) for low-background, 3D super localization of single molecules as well as 3D super-resolution imaging in thick cells. TILT3D is built upon a standard inverted microscope and has minimal custom parts...
February 2018: Proceedings of SPIE
https://www.readbyqxmd.com/read/29678783/safety-and-efficacy-of-stereotactic-radioablation-targeting-pulmonary-vein-tissues-in-an-experimental-model
#13
Paul C Zei, Doug Wong, Edward Gardner, Thomas Fogarty, Patrick Maguire
BACKGROUND: Stereotactic radioablation (SR), a commonly used therapy to treat malignancies, has been utilized to treat refractory ventricular tachycardia, but the feasibility of treating atrial fibrillation (AF) with SR is unknown. OBJECTIVE: We evaluated the safety and efficacy of SR targeting pulmonary vein (PV) antral tissues as potential therapy for AF. METHODS: Seventeen adult canines and two adult swine underwent surgical fiducial marker placement, 3D anatomic rendering CT angiogram of the left atrium (LA), and creation of a treatment plan targeting the right superior pulmonary veins (RSPVs)...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29667117/ecg-derived-respiration-based-on-iterated-hilbert-transform-and-hilbert-vibration-decomposition
#14
Hemant Sharma, K K Sharma
Monitoring of the respiration using the electrocardiogram (ECG) is desirable for the simultaneous study of cardiac activities and the respiration in the aspects of comfort, mobility, and cost of the healthcare system. This paper proposes a new approach for deriving the respiration from single-lead ECG based on the iterated Hilbert transform (IHT) and the Hilbert vibration decomposition (HVD). The ECG signal is first decomposed into the multicomponent sinusoidal signals using the IHT technique. Afterward, the lower order amplitude components obtained from the IHT are filtered using the HVD to extract the respiration information...
April 17, 2018: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/29663272/fiducial-based-fusion-of-3d-dental-models-with-magnetic-resonance-imaging
#15
Amir H Abdi, Alan G Hannam, Sidney Fels
PURPOSE: Magnetic resonance imaging (MRI) is widely used in study of maxillofacial structures. While MRI is the modality of choice for soft tissues, it fails to capture hard tissues such as bone and teeth. Virtual dental models, acquired by optical 3D scanners, are becoming more accessible for dental practice and are starting to replace the conventional dental impressions. The goal of this research is to fuse the high-resolution 3D dental models with MRI to enhance the value of imaging for applications where detailed analysis of maxillofacial structures are needed such as patient examination, surgical planning, and modeling...
April 16, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29658392/reconstruction-of-a-deformed-tumor-based-on-fiducial-marker-registration-a-computational-feasibility-study
#16
Ye Han, Emily Oakley, Gal Shafirstein, Yoed Rabin, Levent Burak Kara
Interstitial photodynamic therapy has shown promising results in the treatment of locally advanced head and neck cancer. In this therapy, systemic administration of a light-sensitive drug is followed by insertion of multiple laser fibers to illuminate the tumor and its margins. Image-based pretreatment planning is employed in order to deliver a sufficient light dose to the complex locally advanced head-and-neck cancer anatomy, in order to meet clinical requirements. Unfortunately, the tumor may deform between pretreatment imaging for the purpose of planning and intraoperative imaging when the plan is executed...
January 1, 2018: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29652670/multi-layer-imager-design-for-mega-voltage-spectral-imaging
#17
Marios E Myronakis, Yue-Houng Hu, Rony Fueglistaller, Adam Wang, Paul Baturin, Pascal Huber, Daniel Morf, Josh M Star-Lack, Ross I Berbeco
The architecture of multi-layer imagers (MLIs) can be exploited to provide megavoltage spectral imaging (MVSPI) for specific imaging tasks. In the current work, we investigated bone suppression and gold fiducial contrast enhancement as two clinical tasks which could be improved with spectral imaging. A method based on analytical calculations that enables rapid investigation of MLI component materials and thicknesses was developed and validated against Monte Carlo computations. The figure of merit for task-specific imaging performance was the contrast-to-noise ratio (CNR) of the gold fiducial when the CNR of bone was equal to zero after a weighted subtraction of the signals obtained from each MLI layer...
April 13, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29644256/registration-and-alignment-between-in-vivo-functional-and-cytoarchitectonic-maps-of-mouse-visual-cortex
#18
Jun Zhuang, Quanxin Wang, Marc Takeno, Jack Waters
This protocol describes a method for registration of in vivo cortical retinotopic map with cytochrome c oxidase (CO) labeled architectonic maps of the same mouse brain through the alignment of vascular fiducials. By recording surface blood vessel pattern and sequential alignment at each step, this method overcomes the challenge imposed by tissue distortion during perfusion, mounting, sectioning and histology procedures. This method can also be generalized to register and align other types of in vivo functional maps like ocular dominance map and spatial/temporal frequency tuning map with various anatomical maps of mouse cortex...
February 20, 2018: Bio-protocol
https://www.readbyqxmd.com/read/29623867/image-based-food-portion-size-estimation-using-a-smartphone-without-a-fiducial-marker
#19
Yifan Yang, Wenyan Jia, Tamara Bucher, Hong Zhang, Mingui Sun
OBJECTIVE: Current approaches to food volume estimation require the person to carry a fiducial marker (e.g. a checkerboard card), to be placed next to the food before taking a picture. This procedure is inconvenient and post-processing of the food picture is time-consuming and sometimes inaccurate. These problems keep people from using the smartphone for self-administered dietary assessment. The current bioengineering study presents a novel smartphone-based imaging approach to table-side estimation of food volume which overcomes current limitations...
April 6, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29621319/dosimetric-impact-of-intra-fraction-prostate-motion-under-a-tumour-tracking-system-in-hypofractionated-robotic-radiosurgery
#20
Yuhei Koike, Iori Sumida, Hirokazu Mizuno, Hiroya Shiomi, Keita Kurosu, Seiichi Ota, Yasuo Yoshioka, Osamu Suzuki, Keisuke Tamari, Kazuhiko Ogawa
For CyberKnife-mediated prostate cancer treatment, a tumour-tracking approach is applied to correct the target location by acquiring X-ray images of implanted fiducial markers intermittently. This study investigated the dosimetric impact of intra-fraction prostate motion during CyberKnife treatment. We retrospectively analyzed 16 patients treated using the CyberKnife (35 Gy delivered in five fractions). Using log files of recorded prostate motion, the intra-fraction prostate motion was simulated. We defined the worst-case intra-fraction prostate motion as the difference between pre- and post-deviation on log files and shifted structure sets according to the corresponding offsets for each beam...
2018: PloS One
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