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https://www.readbyqxmd.com/read/30020508/adipose-tissue-inflammation-and-adrenomedullin-overexpression-contribute-to-lipid-dysregulation-in-diabetic-pregnancies
#1
Yuanlin Dong, Madhu Chauhan, Ancizar Betancourt, Michael Belfort, Chandra Yallampalli
Context: Impaired maternal lipid metabolism in gestational diabetes mellitus (GDM) has detrimental effects on maternal health and fetal growth. We have previously reported excessive expression of adrenomedullin (ADM) and its receptors in GDM adipose tissues when compared with normal glucose tolerant pregnancies. In this study we determine the mechanisms underlying enhanced ADM and its receptors expressions. Design: Omental adipose tissues (OAT) were collected from women during caesarian sections in term pregnancy with non-overweight (NOW, n=9), overweight (OW, n=8), obese (OBS, n=10), and GDM (n=10)...
July 17, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30018895/quality-improvement-and-antioxidant-activity-of-sugar-snap-cookies-prepared-using-blends-of-cereal-flour
#2
Na-Young Lee, Chon-Sik Kang
In this study, we investigated the changes in quality and antioxidant activity of sugar-snap cookies prepared with different blends of refined wheat (WHF) and oat flour (OAF). The crude protein contents of OAF and WHF were 12.24% and 7.17%, respectively, and the fiber contents of were 3.45% and 0.31%, respectively; both were increased by adding OAF. However, the total starch contents were decreased by adding OAF. The β-glucan content of the samples increased considerably upon the addition of OAF. The water-holding capacity was increased after adding OAF compared to WHF (79...
June 2018: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/30016806/long-term-opioid-agonist-treatment-participation-after-first-treatment-entry-is-similar-across-4-european-regions-but-lower-in-non-nationals
#3
Carlos Nordt, Lucas Wiessing, Wil Kuijpers, Jeroen Wisselink, Albert Espelt, M Teresa Brugal, Viktor Mravčik, Blanka Nechanská, Erich Seifritz, Marcus Herdener
Heroin users in opioid agonist treatment (OAT) show markedly reduced heroin consumption, less crime and a lower mortality rate. However, the extent of long-term OAT participation over subsequent treatment episodes remains unclear. We analysed the annual proportion of patients in treatment (at least 1 day) since the start of first OAT in 4 European regions: Barcelona (BA) 1996-2012: 8,602 patients; Czech -Republic (CZ) 2000-2014: 4,377 patients; Netherlands (NL) 1994-2014: 33,235 patients, Zurich (ZU) 1992-2015: 11,795...
July 17, 2018: European Addiction Research
https://www.readbyqxmd.com/read/30016529/higher-whole-grain-intake-is-associated-with-lower-risk-of-type-2-diabetes-among-middle-aged-men-and-women-the-danish-diet-cancer-and-health-cohort
#4
Cecilie Kyrø, Anne Tjønneland, Kim Overvad, Anja Olsen, Rikard Landberg
BACKGROUND: Type 2 diabetes is a major health concern worldwide. Whole grains and cereal fiber may offer protective effects on type 2 diabetes risk. However, few studies have been conducted in cohorts with detailed information on whole-grain cereal intakes and product types and with wide ranges of intake. Objective: We investigated the associations between whole-grain intake, including intakes of different cereal types and products, and the risk of type 2 diabetes in a population with wide and diverse whole-grain intake...
July 17, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/30014365/effect-of-petroleum-derived-substances-on-life-history-traits-of-bird-cherry-oat-aphid-rhopalosiphum-padi-l-and-on-the-growth-and-chemical-composition-of-winter-wheat
#5
Milena Rusin, Janina Gospodarek, Aleksandra Nadgórska-Socha, Gabriela Barczyk, Elżbieta Boligłowa, Marzena Dabioch
The aim of the study was to determine the effects of various petroleum-derived substances (PDSs), namely petrol, diesel fuel, and spent engine oil, on life history traits of the bird cherry-oat aphid Rhopalosiphum padi L., and on the growth and chemical composition of its host plant-winter wheat Triticum aestivum L. Each substance was tested separately, using two concentrations (9 and 18 g kg-1 ). Plants were cultivated in both control and contaminated soils. In early October 2013, soil was contaminated and after 1 week, winter wheat seeds, 'Batuta' cultivar, were sown...
July 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/30012028/understanding-the-care-needs-and-profile-of-people-living-at-home-with-moderate-to-advanced-stage-parkinson-disease
#6
Annette Hand, Lloyd L Oates, William K Gray, Richard W Walker
BACKGROUND: In the United Kingdom, people with Parkinson disease (PD) and atypical parkinsonism will require more support with their care needs as the condition progresses. There are few data on the nature of care input required and the amount of informal and formal care needed by people with PD to enable them to remain within their own home. METHOD: All people with moderate to advanced stage (Hoehn and Yahr III-V) idiopathic PD and atypical parkinsonism under the care of the Northumbria Healthcare NHS Foundation Trust PD service and living in their own home were invited to take part in The Northumbria Care Needs Project, a 10-year prospective longitudinal study...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/30010129/the-gwas-risk-genes-for-depression-may-be-actively-involved-in-alzheimer-s-disease
#7
Hua Ni, Min Xu, Gui-Lai Zhan, Yu Fan, Hejiang Zhou, Hong-Yan Jiang, Wei-Hong Lu, Liwen Tan, Deng-Feng Zhang, Yong-Gang Yao, Chen Zhang
Depression is one of the most frequent psychiatric symptoms observed in people during the development of Alzheimer's disease (AD). We hypothesized that genetic factors conferring risk of depression might affect AD development. In this study, we screened 31 genes, which were located in 19 risk loci for major depressive disorder (MDD) identified by two recent large genome-wide association studies (GWAS), in AD patients at the genomic and transcriptomic levels. Association analysis of common variants was performed by using summary statistics of the International Genomics of Alzheimer's Project (IGAP), and association analysis of rare variants was conducted by sequencing the entire coding region of the 31 MDD risk genes in 107 Han Chinese patients with early-onset and/or familial AD...
July 12, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/30009485/lactobacillus-parafarraginis-zh1-producing-anti-yeast-substances-to-improve-the-aerobic-stability-of-silage
#8
Qinhua Liu, Steven E Lindow, Jianguo Zhang
Enhancing the aerobic stability of silage is very important in silage production. The objective of this study was to compare the roles of a new bacterial strain Lactobacillus parafarraginis ZH1 with Lactobacillus plantarum Chikuso-1 (LP) and Lactobacillus buchneri NCIMB 40788 (LB) in improving the aerobic stability of oat silage and identify the anti-yeast substances produced by them. After ensiled for 45 days, either inoculated silages or control silage were of pH values lower than 4.2. The control and LP inoculated silage had poorer aerobic stability than LB and ZH1 inoculated ones (p < 0...
July 15, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/30001822/perceived-advantages-and-disadvantages-of-oral-anticoagulants-and-the-trade-offs-patients-make-in-choosing-anticoagulant-therapy-and-adhering-to-their-drug-regimen
#9
Melissa C W Vaanholt, Marieke G M Weernink, Clemens von Birgelen, Catharina G M Groothuis-Oudshoorn, Maarten J IJzerman, Janine A van Til
OBJECTIVE: The objective of this study was to explore the perceived advantages and disadvantages of oral anticoagulant therapies (OAT), and the trade-offs patients make in choosing therapy and adhering to their drug regimen. METHODS: Five focus group sessions were conducted across Europe among patients with atrial fibrillation to identify the most important factors impacting OAT's value and adherence. RESULTS: The most frequently identified barriers to OAT were lack of knowledge; poor patient-physician relationships; distraction due to employment or social environment; prior bleeding event(s) or the fear of bleeding; and changes in routine...
June 30, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29999533/engineered-gh11-xylanases-from-orpinomyces-sp-pc-2-improve-techno-functional-properties-of-bread-dough
#10
Amanda Tafuri Paniago Passarinho, Rafaela Zandonade Ventorim, Gabriela Piccolo Maitan-Alfenas, Eduardo Basílio de Oliveira, Valéria Monteze Guimarães
BACKGROUND: Endo-1,4-β-xylanases have remarkable hydrolytic activity towards arabinoxylans and xylanase (xynA), produced by the anaerobic fungus Orpinomyces sp. strain PC-2 was shown to be superior to specific activity, which strongly suggests their applicability in the bakery industry, for the processing of whole-wheat flour containing xylans. In this way, two xylanases from this source, the Small Wild-Type xylanase (SWT) and the Small Mutant xylanase (SM2) (V108A, A199T), were expressed in E...
July 12, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29998945/novel-self-etch-adhesive-with-antibacterial-and-protein-repellent-functions-to-prevent-enamel-demineralization
#11
Bo Wang, Ning Zhang, Xiaomeng Wang, Soo Ro Park, Michael D Weir, Thomas W Oates, Hockin H K Xu, Yuxing Bai
Enamel demineralization is the most undesired side-effect of fixed orthodontic treatments. This study were to develop a novel adhesive that is self-etching instead of using the traditional etching method, and to form a sealant on the enamel to prevent demineralization. 2-methacryloyloxyethyl phosphorylcholine (MPC) and quaternary ammonium dimethylaminohexadecyl methacrylate (DMAHDM) were mixed into a self-etch adhesive (Adper Easy One, 3M, St. Paul, MN, USA; referred to as AEO). Enamel shear bond strength (SBS) was measured...
July 12, 2018: Dental Materials Journal
https://www.readbyqxmd.com/read/29998744/nondestructive-assessment-of-articular-cartilage-electromechanical-properties-after-osteochondral-autologous-and-allogeneic-transplantation-in-a-goat-model
#12
Tomas Mickevicius, Alius Pockevicius, Audrius Kucinskas, Rimtautas Gudas, Justinas Maciulaitis, Arvydas Usas
Objective To determine the applicability of a minimally invasive diagnostic device to evaluate the quality of articular cartilage following autologous (OAT) and allogeneic (OCA) osteochondral graft transplantation in goat model. Design OAT grafts were harvested from lateral femoral condyles (LFCs) and transplanted into osteochondral defects created in medial femoral condyles (MFCs) of contralateral knees. OCA grafts were transplanted into MFC condyles after in vitro storage. Autologous platelet-rich plasma (PRP) was administered intraarticularly after the surgery and at 1 and 2 months postoperatively...
July 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29997720/symptomatic-cholelithiasis-in-an-ectopic-retrocolic-retroduodenal-subhepatic-duplicated-gallbladder
#13
Roman O Kowalchuk, Roman M Kowalchuk, Katia Kaplan-List, Theodore K Oates, Sean C Smith
Gallbladder duplication is a rare anatomic variant of biliary anatomy, which can present diagnostic and treatment challenges. In this case, a 49-year-old male presented with classic symptoms of biliary colic to his primary care physician, and while computed tomography (CT) noted the presence of gallstones, neither CT nor ultrasound was able to locate a gallbladder within the gallbladder fossa. Initial surgery found and cauterized a rudimentary gallbladder, but symptoms persisted, requiring a second surgery and secondary analysis of CT, ultrasound, and magnetic resonance imaging with magnetic resonance cholangiopancreatography...
August 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29995241/secondary-metabolite-production-by-cereal-associated-penicillia-during-cultivation-on-cereal-grains
#14
Magnus Hallas-Møller, Kristian Fog Nielsen, Jens Christian Frisvad
Cereals are vulnerable substrates for fungal growth and subsequent mycotoxin contamination. One of the major fungal genera to colonize the ecosystem of stored grain is Penicillium, especially species in the series of Viridicata and Verrucosa. Culturing these species on grains, we hoped to induce the production of relevant secondary metabolites produced by these fungi in the early stage of cereal breakdown. In a multivariate setup six different cereal grains (wheat, rye, barley, oat, rice, and maize), one kind of white beans, and two standard fungal media, Yeast Extract Sucrose agar (YES agar) and Czapek Yeast Autolysate agar (CYA agar), were inoculated with the ten most important cereal-associated species from Penicillium (P...
July 11, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29993154/-always-say-something-positive-about-the-child-t-berry-brazelton-1918-2018
#15
Kim Oates
No abstract text is available yet for this article.
July 11, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29991946/long-term-dietary-changes-after-diagnosis-of-rheumatoid-arthritis-in-swedish-women-data-from-a-population-based-cohort
#16
Cecilia Lourdudoss, Laurent Arnaud, Alicja Wolk, Ronald F van Vollenhoven, Daniela Di Giuseppe
Objective: To investigate long-term dietary changes after rheumatoid arthritis (RA) diagnosis in Swedish women, compared to women without RA. Methods: This study included 21,602 women from the Swedish Mammography Cohort (SMC), who completed dietary questionnaires in 1997 and 2009. Between 1997 and 2009, 191 women were diagnosed with RA. Dietary changes after RA diagnosis were analyzed based on intake of 82 food items. Statistical analysis included linear mixed models...
2018: International Journal of Rheumatology
https://www.readbyqxmd.com/read/29990648/assessment-of-barrier-severity-and-willingness-to-enter-opioid-agonist-treatment-among-people-who-inject-drugs-in-ukraine
#17
Alexei Zelenev, Portia Shea, Alyona Mazhnaya, Julia Rozanova, Lynn Madden, Ruthanne Marcus, Frederick L Altice
BACKGROUND: Opioid agonist therapies (OAT) in Ukraine were first introduced in 2004 not as addiction treatment, but for HIV prevention. Numerous obstacles have thwarted OAT scale-up, including individual constraints and structural barriers. METHODS: A cross-sectional survey of 1613 opioid dependent people who inject drugs (PWID) were recruited in 2014-2015 using stratified sampling in Kyiv, Odesa, Mykolayiv, Dnipro and Lviv. Analysis was restricted to a subset of 811 PWID who never received OAT...
June 30, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29989018/effect-of-korean-red-ginseng-extracts-on-drug-drug-interactions
#18
Se-Jin Kim, Seungmok Choi, Minsoo Kim, Changmin Park, Gyu-Lee Kim, Si-On Lee, Wonku Kang, Dong-Kwon Rhee
Background: Ginseng has been the subject of many experimental and clinical studies to uncover the diverse biological activities of its constituent compounds. It is a traditional medicine that has been used for its immunostimulatory, antithrombotic, antioxidative, anti-inflammatory, and anticancer effects. Ginseng may interact with concomitant medications and alter metabolism and/or drug transport, which may alter the known efficacy and safety of a drug; thus, the role of ginseng may be controversial when taken with other medications...
July 2018: Journal of Ginseng Research
https://www.readbyqxmd.com/read/29986797/-standard-method-performance-requirements-smprs%C3%A2-2017-021-quantitation-of-wheat-rye-and-barley-gluten-in-oats
#19
Joe Boison, Laura Allred, David Almy, Laura Anderson, Joseph Baumert, Sneh Bhandari, Angel Cebolla, Yumin Chen, Erin Crowley, Carmen Diaz-Amigo, Hirotoshi Doi, Clyde Don, Melanie Downs, Nyla Dubiel, Benjamin Dyer, Luke Emerson, Michael Farrow, Ron Fritz, Carlos Galera, Eric Garber, Samuel Godefroy, Thomas Grace, Rupert Hochegger, Kurt Johnson, Prabhakar Kasturi, Terry Koerner, Markus Lacorn, Frank Massong, Patti Meinhardt, Tracy Mui, Mary O'Meara, Shang-Jing Pan, Bert Popping, Michael Prinster, Elena Quesada, Scott Radcliffe, Katharina Scherf, Girdhari Sharma, Masahiro Shoji, Melonie Stoughton, Lynne Sweeney, John Szpylka, Stephen Taylor, Sheryl Tittlemier, Catherine Torgler, Paul Wehling, Jupiter Yeung, Jerry Zweigenbaum
No abstract text is available yet for this article.
July 1, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29985603/avenanthramide-aglycones-and-glucosides-in-oat-bran-chemical-profile-levels-in-commercial-oat-products-and-cytotoxicity-to-human-colon-cancer-cells
#20
Wenbin Wu, Yao Tang, Junli Yang, Emmanuel Idehen, Shengmin Sang
Avenanthramides (AVAs), unique phytochemicals in oat, have attracted an increasing amount of attention due to their outstanding health benefits. However, the chemical profile and the levels of AVAs in commercial oat products as well as their health benefits have not been examined in detail. In the present study, a total of twenty-nine AVA aglycones and AVA glucosides were identified and characterized from oat bran, using NMR (1D- and 2D-NMR) and LC-MS techniques. Among them, seventeen novel AVA glucosides were reported in oat bran for the first time...
July 9, 2018: Journal of Agricultural and Food Chemistry
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