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https://www.readbyqxmd.com/read/27914029/mid-term-results-and-responsiveness-predictors-after-two-step-single-anastomosis-duodeno-ileal-bypass-with-sleeve-gastrectomy
#1
José M Balibrea, Ramón Vilallonga, Marta Hidalgo, Andreea Ciudin, Óscar González, Enric Caubet, Andrés Sánchez-Pernaute, José M Fort, Manel Armengol-Carrasco
BACKGROUND: In patients with insufficient weight loss after sleeve gastrectomy (SG) or in super obese individuals, among many surgical options available, a single-anastomosis duodeno-ileal bypass (SADI) after SG (SADI-S) could be considered. Due to the limited information available about the use of SADI as a second-step procedure, the objective of this study was to evaluate the mid-term results and responsiveness of SADI after sleeve gastrectomy. METHODS: We present prospective data from 30 consecutive patients with a mean BMI of 40...
December 2, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27683784/sadi-s-with-right-gastric-artery-ligation-technical-systematization-and-early-results
#2
Jordi Pujol Gebelli, Amador Garcia Ruiz de Gordejuela, Almino Cardoso Ramos, Mario Nora, Ana Marta Pereira, Josemberg Marins Campos, Manoela Galvão Ramos, Eduardo Lemos de Souza Bastos, João Batista Marchesini
Background: Bariatric surgery is performed all over the world with close to 500.000 procedures per year. The most performed techniques are Roux-en-Y gastric bypass and sleeve gastrectomy. Despite this data, the most effective procedure, biliopancreatic diversion with or without duodenal switch, represents only no more than 1.5% of the procedures. Technical complexity, morbidity, mortality, and severe nutritional adverse effects related to the procedure are the main fears that prevent most universal acceptance...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27683783/safety-and-effectiveness-of-single-anastomosis-duodenal-switch-procedure-preliminary-result-from-a-single-institution
#3
Lars Nelson, Rena C Moon, Andre F Teixeira, Manoel Galvão, Almino Ramos, Muhammad A Jawad
Background: Single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) was introduced into bariatric surgery by Sanchez-Pernaute et al. as an advancement of the biliopancreatic diversion with duodenal switch. Aim: To evaluate the SADI-S procedure with regard to weight loss, comorbidity resolution, and complication rate in the super obese population. Methods: A retrospective chart review was performed on initial 72 patients who underwent laparoscopic or robot-assisted laparoscopic SADI-S between December 17th, 2013 and July 29th, 2015...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27455393/the-surgical-challenge-of-carotid-artery-and-fallopian-canal-dehiscence-in-chronic-ear-disease-a-pitfall-for-endoscopic-approach
#4
H F Pauna, R C Monsanto, P A Schachern, S S Costa, G Kwon, M M Paparella, S Cureoglu
OBJECTIVE: Endoscopic procedures are becoming common in middle ear surgery. Inflammation due to chronic ear disease can cause bony erosion of the carotid artery and Fallopian canals, making them more vulnerable during surgery. The objective of this study was to determine whether or not chronic ear disease increases dehiscence of the carotid artery and Fallopian canals. DESIGN: Comparative human temporal bone study. SETTING: Otopathology laboratory...
July 25, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/26718344/evaluation-of-novel-metrics-of-symptom-relief-in-acute-heart-failure-the-worst-symptom-score
#5
Omar F AbouEzzeddine, Yee Weng Wong, Robert J Mentz, Sadi S Raza, Jose Nativi-Nicolau, Robb D Kociol, Steven E McNulty, Kevin J Anstrom, Adrian F Hernandez, Margaret M Redfield
OBJECTIVE: To characterize a novel "worst"-symptom visual analogue scale (WS-VAS) versus the traditional dyspnea visual analogue scale (DVAS) in an acute heart failure (AHF) trial. BACKGROUND: AHF trials assess symptom relief as a pivotal endpoint with the use of dyspnea scores. However, many AHF patients' worst presenting symptom (WS) may not be dyspnea. We hypothesized that a WS-VAS may reflect clinical improvement better than DVAS in AHF. METHODS AND RESULTS: AHF patients (n = 232) enrolled in the Renal Optimization Strategies Evaluation in Acute Heart Failure (ROSE-AHF) Trial indicated their WS at enrollment and completed DVAS and WS-VAS at enrollment and 24, 48, and 72 hours...
November 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/26610027/utility-of-two-modified-live-virus-canine-distemper-vaccines-in-wild-caught-fishers-martes-pennanti
#6
Steven T Peper, Randall L Peper, Denise H Mitcheltree, George V Kollias, Robert P Brooks, Sadie S Stevens, Thomas L Serfass
BACKGROUND: Canine distemper virus (CDV) infects families in the order Carnivora. As a preventive measure, vaccinations against CDV are frequently given to mustelids in captive environments. OBJECTIVES: Our objectives were to compare the utility between two modified-live virus canine distemper vaccines (MLV CDV's), Fervac-D® (no longer manufactured) and Galaxy-D® (now manufactured by MSD Animal Health as part of a multivalent vaccine), in developing an immune response in wild-caught fishers...
November 26, 2015: Veterinary Quarterly
https://www.readbyqxmd.com/read/26555109/low-titers-of-canine-distemper-virus-antibody-in-wild-fishers-martes-pennanti-in-the-eastern-usa
#7
Steven T Peper, Randall L Peper, Denise H Mitcheltree, George V Kollias, Robert P Brooks, Sadie S Stevens, Thomas L Serfass
Canine distemper virus (CDV) infects species in the order Carnivora. Members of the family Mustelidae are among the species most susceptible to CDV and have a high mortality rate after infection. Assessing an animal's pathogen or disease load prior to any reintroduction project is important to help protect the animal being reintroduced, as well as the wildlife and livestock in the area of relocation. We screened 58 fishers for CDV antibody prior to their release into Pennsylvania, US, as part of a reintroduction program...
January 2016: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/26154844/hearing-impairment-in-children-and-adults-with-acquired-middle-ear-cholesteatoma-audiometric-comparison-of-385-ears
#8
COMPARATIVE STUDY
Letícia P S Rosito, Luciana S Netto, Adriane R Teixeira, Sady S da Costa
OBJECTIVE: Evaluate hearing impairment in acquired middle ear cholesteatoma and investigate audiometric differences between children and adults. STUDY DESIGN: Cross-sectional comparative study. SETTING: Tertiary hospital. PATIENTS: Three hundred twenty-three consecutive patients diagnosed as having acquired middle ear cholesteatoma in at least one ear (385 ears) between August 2000 and March 2013 and no surgical history (mean [standard deviation {SD}] age, 32...
September 2015: Otology & Neurotology
https://www.readbyqxmd.com/read/26048517/single-anastomosis-duodenoileal-bypass-with-sleeve-gastrectomy-sadi-s-for-obese-diabetic-patients
#9
Andrés Sánchez-Pernaute, Miguel Ángel Rubio, Lucio Cabrerizo, Ana Ramos-Levi, Elia Pérez-Aguirre, Antonio Torres
BACKGROUND: Bariatric operations achieve a high remission rate of type 2 diabetes in patients with morbid obesity. Malabsorptive operations usually are followed by a higher rate of metabolic improvement, though complications and secondary effects of these operations are usually higher. OBJECTIVES: Analyze the results of a simplified duodenal switch, the single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) on patients with obesity and type 2 diabetes mellitus (T2 DM)...
September 2015: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/26022923/is-klotho-f352v-polymorphism-the-missing-piece-of-the-bone-loss-puzzle-in-renal-transplant-recipients
#10
Sebahat Ozdem, Vural Taner Yılmaz, Sadi S Ozdem, Levent Donmez, Ramazan Cetinkaya, Gultekin Suleymanlar, F Fevzi Ersoy
BACKGROUND: Bone disorders are next to cardiovascular problems in frequency in renal transplant (RT) recipients. Reduction in 1,25-dihydroxycholecalciferol (1,25D) levels is among the reasons causing bone loss in these patients. Klotho (KL) serves as a co-receptor for fibroblast growth factor 23 (FGF23), and functions in vitamin D metabolism. KL polymorphisms have been identified in several studies, and phenylalanine to valine substitution at amino acid position 352 seemed to be important to KL function...
2015: Pharmacology
https://www.readbyqxmd.com/read/25314818/efficacy-of-two-canine-distemper-vaccines-in-wild-nearctic-river-otters-lontra-canadensis
#11
Steven T Peper, Randall L Peper, George V Kollias, Robert P Brooks, Sadie S Stevens, Thomas L Serfass
Canine distemper virus (CDV), a contagious morbillivirus, infects families in the order Carnivora, including Nearctic river otters (Lontra canadensis). As a preventative measure, vaccinations against CDV are frequently given to mustelids in captive environments. The Pennsylvania River Otter Reintroduction Project (PRORP) used wild-caught river otters to evaluate the efficacy and need for vaccinations against CDV as part of any reintroduction project. The objectives of this study were to: 1) evaluate the prevalence of exposure to CDV in wild river otters, 2) determine the immunologic response of river otters (i...
September 2014: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/24909165/nuclear-translocation-of-igf-1r-via-p150-glued-and-an-importin-%C3%AE-ranbp2-dependent-pathway-in-cancer-cells
#12
S Packham, D Warsito, Y Lin, S Sadi, R Karlsson, B Sehat, O Larsson
Mounting evidence has shown that the insulin-like growth factor-1 receptor (IGF-1R) has critical roles in cancer cell growth. This has prompted pharmacological companies to develop agents targeting the receptor. Surprisingly, clinical trials using specific IGF-1R antibodies have, however, revealed disappointing results. Further understanding of the role of IGF-1R in cancer cells is therefore necessary for development of efficient therapeutic strategies. Recently, we showed that IGF-1R is sumoylated and translocated into the cell nucleus where it activates gene transcription...
April 23, 2015: Oncogene
https://www.readbyqxmd.com/read/24887687/effects-of-glucagon-like-peptide-1-in-diabetic-rat-small-resistance-arteries
#13
Zeliha Bayram, Cahit Nacitarhan, Sadi S Ozdem
We investigated the functional effects of glucagon-like peptide-1 [GLP-1(7-36)] and GLP-1(9-36) and the mechanism(s) playing a role in the effects of these agents in isolated small resistance arteries from control and diabetic rats. Cumulative concentrations of GLP-1(7-36) and GLP-1(9-36) produced concentration-dependent relaxations in endothelium-intact but not endothelium-denuded arteries that were significantly decreased in diabetic rats. GLP-1 receptor antagonist exendin(9-39) significantly inhibited responses to GLP-1 analogs...
September 2014: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/21245203/the-effect-of-ascorbic-acid-supplementation-on-endosulfan-toxicity-in-rabbits
#14
Sebahat Ozdem, Cahit Nacitarhan, Mehmet S Gulay, Fatma S Hatipoglu, Sadi S Ozdem
We investigated the endosulfan-induced alterations and the effect of vitamin C supplementation on endosulfan-induced alterations in serum biochemical markers of oxidative stress and antioxidant capacity in rabbits. Basal, 4th and 6th week serum levels of total oxidant status (TOS), thiobarbituric acid reactive substances (TBARS), advanced oxidation protein products (AOPP), total antioxidant capacity (TAC), total protein sulfhydryl (T-SH) and glutathione-S-transferase (GST) were measured in rabbits administered endosulfan (1 mg/kg) alone or in combination with vitamin C (20 mg/kg) for 6 weeks...
June 2011: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/20798995/single-anastomosis-duodeno-ileal-bypass-with-sleeve-gastrectomy-sadi-s-one-to-three-year-follow-up
#15
Andrés Sánchez-Pernaute, Miguel Angel Rubio Herrera, María Elia Pérez-Aguirre, Pablo Talavera, Lucio Cabrerizo, Pilar Matía, Luis Díez-Valladares, Ana Barabash, Estaban Martín-Antona, Alejandra García-Botella, Ester Martín Garcia-Almenta, Antonio Torres
Single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is a new operation for morbid obesity based on the biliopancreatic diversion in which a sleeve gastrectomy is followed by an end-to-side duodeno-ileal diversion. The preservation of the pylorus makes possible the reconstruction in one loop, which reduces operating time and needs no mesentery opening. We review the results obtained on the first 50 operated patients with 1 to 3 years follow-up. Eighteen men and 32 women with a mean BMI of 44 kg/m(2) were operated on...
December 2010: Obesity Surgery
https://www.readbyqxmd.com/read/20562340/insulin-enhances-the-effect-of-nitric-oxide-at-inhibiting-neointimal-hyperplasia-in-a-rat-model-of-type-1-diabetes
#16
Vinit N Varu, Sadie S Ahanchi, Melissa E Hogg, Hussein A Bhikhapurwala, Amy Chen, Daniel A Popowich, Ashley K Vavra, Janet Martinez, Qun Jiang, Joseph E Saavedra, Joseph A Hrabie, Larry K Keefer, Melina R Kibbe
Diabetes confers greater restenosis from neointimal hyperplasia following vascular interventions. While localized administration of nitric oxide (NO) is known to inhibit neointimal hyperplasia, the effect of NO in type 1 diabetes is unknown. Thus the aim of this study was to determine the efficacy of NO following arterial injury, with and without exogenous insulin administration. Vascular smooth muscle cells (VSMC) from lean Zucker (LZ) rats were exposed to the NO donor, DETA/NO, following treatment with different glucose and/or insulin concentrations...
September 2010: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/20079376/the-role-of-nitric-oxide-and-potassium-channels-in-the-effect-of-adrenomedullin-in-human-internal-thoracic-arteries
#17
Zeliha Bayram, Ilhan Golbasi, Sadi S Ozdem
We investigated the effects of adrenomedullin (ADM) and the role(s) of cyclooxygenase, nitric oxide (NO) synthase and potassium channels in the effects of ADM in human internal thoracic artery (ITA) rings. Samples of redundant ITA rings were suspended in organ baths and isometric tension was continuously recorded. ADM (10(-10)-10(-7)M) produced concentration-dependent relaxation responses in ITA rings precontracted by phenylephrine. The relaxant responses to ADM were significantly higher in endothelium-intact than denuded preparations...
April 9, 2010: Regulatory Peptides
https://www.readbyqxmd.com/read/18444889/monovalent-virus-like-particle-vaccine-protects-guinea-pigs-and-nonhuman-primates-against-infection-with-multiple-marburg-viruses
#18
Dana L Swenson, Kelly L Warfield, Tom Larsen, D Anthony Alves, Sadie S Coberley, Sina Bavari
BACKGROUND: Virus-like particle (VLP)-based vaccines have the advantage of being morphologically and antigenically similar to the live virus from which they are derived. Expression of the glycoprotein and VP40 matrix protein from Lake Victoria marburgvirus (MARV) results in spontaneous production of VLPs in mammalian cells. Guinea pigs vaccinated with Marburg virus VLPs (mVLPs) or inactivated MARV (iMARV) develop homologous humoral and T-cell responses and are completely protected from a lethal homologous MARV challenge...
May 2008: Expert Review of Vaccines
https://www.readbyqxmd.com/read/17906499/contralateral-ear-in-chronic-otitis-media-a-histologic-study
#19
Letícia Petersen Schmidt Rosito, Sady S da Costa, Patricia A Schachern, Cristina Dornelles, Sebahatin Cureoglu, Michael M Paparella
OBJECTIVE: The objective of this study is to determine the prevalence of the contralateral ear changes in human temporal bones of donors with chronic otitis media. STUDY DESIGN: Transversal. MATERIAL AND METHODS: The temporal bones were examined under light microscopy and then described. Chronic otitis media was defined by the presence of irreversible inflammatory alterations in the middle ear cleft. The contralateral ear was defined as the normal or the less affected ear...
October 2007: Laryngoscope
https://www.readbyqxmd.com/read/17706378/two-herpesviruses-associated-with-disease-in-wild-atlantic-loggerhead-sea-turtles-caretta-caretta
#20
Brian A Stacy, James F X Wellehan, Allen M Foley, Sadie S Coberley, Lawrence H Herbst, Charles A Manire, Michael M Garner, Milagros D Brookins, April L Childress, Elliott R Jacobson
Herpesviruses are associated with lung-eye-trachea disease and gray patch disease in maricultured green turtles (Chelonia mydas) and with fibropapillomatosis in wild sea turtles of several species. With the exception fibropapillomatosis, no other diseases of wild sea turtles of any species have been associated with herpesviral infection. In the present study, six necropsied Atlantic loggerhead sea turtles (Caretta caretta) had gross and histological evidence of viral infection, including oral, respiratory, cutaneous, and genital lesions characterized by necrosis, ulceration, syncytial cell formation, and intranuclear inclusion bodies...
January 1, 2008: Veterinary Microbiology
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