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"hypertriglyceridemic waist phenotype"

Roberta Souza Freitas, Maria de Jesus Mendes da Fonseca, Maria Inês Schmidt, Maria Del Carmen Bisi Molina, Maria da Conceição Chagas de Almeida
This study's objectives were to estimate the prevalence of hypertriglyceridemic waist (HTW) phenotype in participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), identify associated risk factors, and compare with other cardiovascular and metabolic risk indicators. This was a cross-sectional study with baseline data from a cohort of public employees. HTW is defined as the simultaneous presence of increased waist circumference (WC) (≥ 80cm for women, ≥ 90cm for men according to the International Diabetes Federation - IDF; and ≥ 88cm for women, ≥ 102cm for men according to the U...
March 29, 2018: Cadernos de Saúde Pública
W Wang, C Shen, H Zhao, W Tang, S Yang, J Li, Z Ren, Y Zhao
OBJECTIVES: The hypertriglyceridemic waist phenotype has been reported as a practical tool to screen people with an increased risk of coronary artery disease and type 2 diabetes. The aim of this study was to investigate the relationship between the phenotype and ischemic stroke in a rural population in south China. MATERIALS AND METHODS: A total of 4081 participants aged over 35 years old without a stroke history were surveyed in 2009 and followed up from May 2014 to January 2016...
March 25, 2018: Acta Neurologica Scandinavica
Chaomin Zhou, Yongqiang Li, Xiaofei Shao, Hequn Zou
PURPOSE: Assessing and comparing the ability of the hypertriglyceridemic waist (HW) phenotype and anthropometric obesity indexes to identify subjects at high risk of chronic kidney disease (CKD) in a relatively lean population in South China. METHODS: Using data from a community-based, cross-sectional study conducted in Zhuhai City, Southern China, we examined associations between the HW phenotype, anthropometric obesity indexes, and incident CKD risk in a relatively lean population...
January 25, 2018: Eating and Weight Disorders: EWD
Juliana Rodrigues de Andrade, Gustavo Velasquez-Melendez, Sandhi Maria Barreto, Taísa Sabrina Silva Pereira, José Geraldo Mill, Maria Del Carmen Bisi Molina
OBJECTIVE: To investigate the association between fat and fiber intakes and the hypertriglyceridemic waist phenotype (HWP). METHODS: Cross-sectional survey conducted from the baseline of Brazilian Longitudinal Study of Health Adult (ELSA-Brasil). Anthropometric measurements were conducted and the body mass index was calculated (BMI). Participants were classified according to the presence of HWP when waist circumference ≥ 102 and ≥ 88 cm, respectively, in men and women, and triglycerides ≥ 150 mg/dL...
July 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Valeria Calcaterra, Rachele De Giuseppe, Ginevra Biino, Melissa Mantelli, Sonia Marchini, Giulia Bendotti, Alexandra Madè, Maria Antonietta Avanzini, Chiara Montalbano, Gianguido Cossellu, Daniela Larizza, Hellas Cena
BACKGROUND: The association between oxidative stress (OS) and metabolic syndrome (MetS) has been reported in adults. We analyzed the relation between circulating oxidized low-density lipoproteins (Ox-LDL) and MetS in pediatric ages in order to define whether plasma Ox-LDL levels are correlated to obesity and whether oxidative damage, using serum Ox-LDL levels as a proxy, are associated with MetS. METHODS: We enrolled 178 children (11.8±2.6 years). On the basis of a body mass index (BMI) threshold, the subjects were classified as: normal weight BMI <75th percentile; overweight BMI 75-97th percentile; obese BMI >97th percentile...
November 27, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
Chun-Ming Ma, Rui Wang, Xiao-Li Liu, Na Lu, Qiang Lu, Fu-Zai Yin
Background/Aims: The aim of this study was to explore the relationship between hypertriglyceridemic waist (HW) phenotype and early diabetic nephropathy in type 2 diabetes. Methods: A cross-sectional study was conducted on 538 type 2 diabetes patients in Qinhuangdao. The HW phenotype was defined as serum triglyceride concentrations ≥1.7 mmol/L and waist circumference ≥90 cm (males) and ≥85 cm (females). Results: The prevalence of the HW phenotype was 34...
October 2017: Cardiorenal Medicine
Marina Augusta Dias Braz, Jallyne Nunes Vieira, Flayane Oliveira Gomes, Priscilla Rafaella da Silva, Ohanna Thays de Medeiros Santos, Ilanna Marques Gomes da Rocha, Iasmin Matias de Sousa, Ana Paula Trussardi Fayh
OBJECTIVE: We aimed to evaluate the prevalence of hypertriglyceridemic waist (HTGW) phenotype among users of primary health care using two different cutoff points used in the literature. METHODS: We evaluated adults and elderly individuals of both sexes who attended the same level of primary health care. HTGW phenotype was determined with measurements of waist circumference (WC) and triglyceride levels and compared using cutoff points proposed by the National Cholesterol Education Program - NCEP/ATP III (WC ≥102 cm for men and ≥88 cm for women; triglyceride levels ≥150 mg/dL for both sexes) and by Lemieux et al (WC ≥90 cm for men and ≥85 cm for women; triglyceride levels ≥177 mg/dL for both)...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Valérie Lévesque, Paul Poirier, Jean-Pierre Després, Natalie Alméras
Although cardiovascular disease (CVD) and diabetes mellitus are largely lifestyle driven, lifestyle metrics are not used in clinical practice. This study examined the relevance of using a simple lifestyle risk score designed for primary care medicine by testing its ability to predict biological CVD risk factors in a cohort of 3,712 individuals involved in a workplace health evaluation or management program ("Grand Défi Entreprise" project). Using a lifestyle risk score based on waist circumference, fitness, nutritional quality, and physical activity level, employees were categorized into 3 distinct estimated lifestyle risk levels (low, intermediate, and high)...
December 1, 2017: American Journal of Cardiology
Priscila Ribas de Farias Costa, Ana Marlúcia Oliveira Assis, Carla de Magalhães Cunha, Emile Miranda Pereira, Gabriela Dos Santos de Jesus, Lais Eloy Machado da Silva, Wilanne Pinheiro de Oliveira Alves
Background: The hypertriglyceridemic waist (HTW) phenotype is defined as the simultaneous presence of increased waist circumference (WC) and serum triglycerides (TG) levels and it has been associated with cardiometabolic risk in children and adolescents. Objective: The objective was to evaluate the influence of HTW phenotype in the fasting glycemia and blood pressure in children and adolescents over one-year follow-up period. Methods: It is a cohort study involving 492 children and adolescents from 7 to 15 years old, both genders, who were submitted to anthropometric, biochemical and clinical evaluation at the baseline, and also after 6 and 12 months of follow-up...
July 2017: Arquivos Brasileiros de Cardiologia
Mohsen Janghorbani, Mohammad Reza Salamat, Ashraf Aminorroaya, Masoud Amini
BACKGROUND: The aim of this study was to assess the utility of the visceral adiposity index (VAI) and the hypertriglyceridemic waist (HTGW) phenotype as possible hypertension (HTN) predictors in a high-risk population without diabetes and HTN. METHODS: Incident HTN over a 7-year follow-up was assessed among 1,375 first-degree non-diabetic and non-hypertensive relatives of consecutive patients with type 2 diabetes who were 30 to 70 years of age. HTN was defined as a blood pressure reading ≥140/90 mm Hg or the use of antihypertensive medications...
June 2017: Endocrinology and Metabolism
Camila Weschenfelder, Aline Marcadenti, Airton Tetelbom Stein, Catarina Bertaso Andreatta Gottschall
CONTEXT AND OBJECTIVE: The association of serum triglycerides plus waist circumference seems to be a good marker of cardiovascular risk and has been named the "hypertriglyceridemic waist" phenotype. The aim of our study was to investigate the association between the hypertriglyceridemic waist phenotype and HDL-cholesterol among patients with heart failure. DESIGN AND SETTING: Cross-sectional study in a tertiary-level hospital in southern Brazil. METHODS: We included patients with heart failure aged > 40 years...
January 2017: São Paulo Medical Journal, Revista Paulista de Medicina
Ľ Cibičková, K Langová, H Vaverková, V Kubíčková, D Karásek
Hyperuricemia has been described as associated with the risk of development metabolic syndrome; however the relationship between the uric acid level and particular parameters of metabolic syndrome remained unclear. We performed a cross-sectional study on a cohort of 833 dyslipidemic patients and correlated their levels of uric acid with parameters of insulin resistance, lipid metabolism, C-reactive protein, anthropometric parameters. We also defined patients with hypertriglyceridemic waist phenotype and compered their uric acid levels with those without this phenotype...
July 18, 2017: Physiological Research
Shuang Chen, Xiaofan Guo, Siyuan Dong, Shasha Yu, Yintao Chen, Naijin Zhang, Yingxian Sun
The present study aimed to evaluate the relationship between the hypertriglyceridemic waist (HTGW) phenotype and hyperuricemia. We undertook a cross-sectional study with a sample of 11,576 adults from China. The HTGW phenotype was defined as elevated waist circumference (WC) and elevated triglyceride (TG) concentration. Logistic regression analysis was used to evaluate the association between the HTGW phenotype and hyperuricemia. The prevalence of hyperuricemia was significantly higher in individuals with the HTGW phenotype, as compared to those with the normal waist normal triglyceride (NWNT) group (25...
May 2017: Clinical Rheumatology
Jing Zeng, Miao Liu, Lei Wu, Jianhua Wang, Shanshan Yang, Yiyan Wang, Yao Yao, Bin Jiang, Yao He
Background : The primary objective of this study was to explore the association of hypertriglyceridemic waist (HTGW) phenotype with chronic kidney disease (CKD) and its sex difference in an urban Chinese elderly population. Methods : In a cross-sectional study, a total of 2102 participants aged 60-95 years were recruited and classified into four phenotypes: normal waist-normal triglyceride (NWNT), normal waist-elevated triglycerides (NWET), elevated waist-normal triglycerides (EWNT), and HTGW. Logistic regression analysis was used to estimate the associations of interest...
December 13, 2016: International Journal of Environmental Research and Public Health
Shuang Chen, Xiaofan Guo, Shasha Yu, Hongmei Yang, Guozhe Sun, Zhao Li, Yingxian Sun
The aim of this study was to evaluate the relationship between the hypertriglyceridemic waist (HTGW) phenotype and metabolic abnormalities in hypertensive adults.A cross-sectional study, with a sample of 5919 hypertensive adults (2892 men and 3027 women) aged 35 years or older, was recruited from rural areas of China. The participants underwent anthropometric measurements and laboratory examinations. The self-reported information was collected by trained personnel. The HTGW phenotype was defined as elevated triglycerides and elevated waist circumference...
December 2016: Medicine (Baltimore)
Ahmet Karagöz, Altan Onat, Mesut Aydın, Günay Can, Barış Şimşek, Murat Yüksel
OBJECTIVE: The associations of total testosterone (TT) and sex hormone-binding globulin (SHBG) with the hypertriglyceridemic waist (HtgW) phenotype and coronary heart disease (CHD) risk have scarcely been examined. We explored such cardiometabolic risk mediations in middle-aged adults. METHODS: Participants (n = 1924) in a population-based study were studied by forming categories consisting of abdominal obesity, hypertriglyceridemia, both (HtgW), or none ('healthy')...
March 2017: Postgraduate Medicine
Mercè Fernández-Miró, Juan J Chillarón, Mercè Albareda, Sara Fontserè, Cristina Colom, Lluís Vila, Juan Pedro-Botet, Juana A Flores LE-Roux
BACKGROUND: The hypertriglyceridemic waist has been linked to a higher number of cardiovascular risk factors and a greater probability of developing diabetes and cardiovascular disease. Around 50% of individuals with type 1 diabetes (T1D) are overweight or obese and triglyceridemia is associated with the onset of micro- and macrovascular complications. METHODS: A cross-sectional study was conducted in men with T1D to assess the association between the prevalence of hypertriglyceridemic waist and cardiovascular risk factors and hypogonadism...
March 2017: Minerva Endocrinologica
Francieli Barreiro-Ribeiro, Ana Carolina Junqueira Vasques, Cleliani de Cassia da Silva, Mariana Porto Zambon, Ana Maria De Bernardi Rodrigues, Daniella Fernandes Camilo, Maria Ângela Reis de Góes Monteiro Antonio, Ana Raimunda Dâmaso, Raquel Munhoz da Silveira Campos, Sergio Tufik, Marco Túlio de Mello, Bruno Geloneze
OBJECTIVE: This study aimed to identify cutoff points for detecting hypertriglyceridemic waist phenotype (HTWP) in adolescents and to investigate the association of the HTWP with insulin resistance (IR) and metabolic syndrome components. METHODS: A multicentric cross-sectional study of 861 adolescents (10-19 years of age, 504 girls) was conducted. Pubertal stage, anthropometric, and laboratory parameters were assessed. IR was assessed by Homeostasis Model Assessment for Insulin Resistance (HOMA1-IR) index and hyperglycemic clamp (n = 80)...
December 2016: Childhood Obesity
Kang Chen, Ping Li, Yi-Jun Li, Ting Li, Yi-Ming Mu
OBJECTIVE: To investigate the association between hypertriglyceridemic waist (HTGW) phenotype and arterial stiffness in a Chinese population without hypertension, diabetes and cardiovascular diseases. METHODS: A total number of 3028 subjects aged 40 years and over were enrolled in this cross-sectional study. All participants provided a clinical history and underwent a physical examination. Brachial-ankle pulse wave velocity (baPWV) was used to evaluate arterial stiffness...
November 2016: Postgraduate Medicine
Roya Kelishadi, Fahimeh Jamshidi, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Ramin Heshmat, Gelayol Ardalan, Silva Hovsepian
OBJECTIVE: This study aims to investigate the role of metabolic syndrome (MetS) and the hypertriglyceridemic-waist (HW) phenotype in determining cardiometabolic risk factors and elevated liver enzymes in a national sample of Iranian pediatric population. METHOD: This nationwide study was conducted in the framework of the third survey of a surveillance program. Students, aged 10-18 years, were recruited from 27 provinces in Iran. The prevalence of cardiometabolic risk factors was compared in students with and without HW and MetS...
September 2016: Jornal de Pediatria
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