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"hypertriglyceridemic waist phenotype"

Priscila Ribas de Farias Costa, Ana Marlúcia Oliveira Assis, Carla de Magalhães Cunha, Emile Miranda Pereira, Gabriela Dos Santos de Jesus, Lais Eloy Machado da Silva, Wilanne Pinheiro de Oliveira Alves
Background: The hypertriglyceridemic waist (HTW) phenotype is defined as the simultaneous presence of increased waist circumference (WC) and serum triglycerides (TG) levels and it has been associated with cardiometabolic risk in children and adolescents. Objective: The objective was to evaluate the influence of HTW phenotype in the fasting glycemia and blood pressure in children and adolescents over one-year follow-up period. Methods: It is a cohort study involving 492 children and adolescents from 7 to 15 years old, both genders, who were submitted to anthropometric, biochemical and clinical evaluation at the baseline, and also after 6 and 12 months of follow-up...
July 2017: Arquivos Brasileiros de Cardiologia
Mohsen Janghorbani, Mohammad Reza Salamat, Ashraf Aminorroaya, Masoud Amini
BACKGROUND: The aim of this study was to assess the utility of the visceral adiposity index (VAI) and the hypertriglyceridemic waist (HTGW) phenotype as possible hypertension (HTN) predictors in a high-risk population without diabetes and HTN. METHODS: Incident HTN over a 7-year follow-up was assessed among 1,375 first-degree non-diabetic and non-hypertensive relatives of consecutive patients with type 2 diabetes who were 30 to 70 years of age. HTN was defined as a blood pressure reading ≥140/90 mm Hg or the use of antihypertensive medications...
June 2017: Endocrinology and Metabolism
Camila Weschenfelder, Aline Marcadenti, Airton Tetelbom Stein, Catarina Bertaso Andreatta Gottschall
CONTEXT AND OBJECTIVE: The association of serum triglycerides plus waist circumference seems to be a good marker of cardiovascular risk and has been named the "hypertriglyceridemic waist" phenotype. The aim of our study was to investigate the association between the hypertriglyceridemic waist phenotype and HDL-cholesterol among patients with heart failure. DESIGN AND SETTING: Cross-sectional study in a tertiary-level hospital in southern Brazil. METHODS: We included patients with heart failure aged > 40 years...
January 2017: São Paulo Medical Journal, Revista Paulista de Medicina
Ľ Cibičková, K Langová, H Vaverková, V Kubíčková, D Karásek
Hyperuricemia has been described as associated with the risk of development metabolic syndrome; however the relationship between the uric acid level and particular parameters of metabolic syndrome remained unclear. We performed a cross-sectional study on a cohort of 833 dyslipidemic patients and correlated their levels of uric acid with parameters of insulin resistance, lipid metabolism, C-reactive protein, anthropometric parameters. We also defined patients with hypertriglyceridemic waist phenotype and compered their uric acid levels with those without this phenotype...
February 28, 2017: Physiological Research
Shuang Chen, Xiaofan Guo, Siyuan Dong, Shasha Yu, Yintao Chen, Naijin Zhang, Yingxian Sun
The present study aimed to evaluate the relationship between the hypertriglyceridemic waist (HTGW) phenotype and hyperuricemia. We undertook a cross-sectional study with a sample of 11,576 adults from China. The HTGW phenotype was defined as elevated waist circumference (WC) and elevated triglyceride (TG) concentration. Logistic regression analysis was used to evaluate the association between the HTGW phenotype and hyperuricemia. The prevalence of hyperuricemia was significantly higher in individuals with the HTGW phenotype, as compared to those with the normal waist normal triglyceride (NWNT) group (25...
February 9, 2017: Clinical Rheumatology
Jing Zeng, Miao Liu, Lei Wu, Jianhua Wang, Shanshan Yang, Yiyan Wang, Yao Yao, Bin Jiang, Yao He
Background: The primary objective of this study was to explore the association of hypertriglyceridemic waist (HTGW) phenotype with chronic kidney disease (CKD) and its sex difference in an urban Chinese elderly population. Methods: In a cross-sectional study, a total of 2102 participants aged 60-95 years were recruited and classified into four phenotypes: normal waist-normal triglyceride (NWNT), normal waist-elevated triglycerides (NWET), elevated waist-normal triglycerides (EWNT), and HTGW. Logistic regression analysis was used to estimate the associations of interest...
December 13, 2016: International Journal of Environmental Research and Public Health
Shuang Chen, Xiaofan Guo, Shasha Yu, Hongmei Yang, Guozhe Sun, Zhao Li, Yingxian Sun
The aim of this study was to evaluate the relationship between the hypertriglyceridemic waist (HTGW) phenotype and metabolic abnormalities in hypertensive adults.A cross-sectional study, with a sample of 5919 hypertensive adults (2892 men and 3027 women) aged 35 years or older, was recruited from rural areas of China. The participants underwent anthropometric measurements and laboratory examinations. The self-reported information was collected by trained personnel. The HTGW phenotype was defined as elevated triglycerides and elevated waist circumference...
December 2016: Medicine (Baltimore)
Ahmet Karagöz, Altan Onat, Mesut Aydın, Günay Can, Barış Şimşek, Murat Yüksel
OBJECTIVE: The associations of total testosterone (TT) and sex hormone-binding globulin (SHBG) with the hypertriglyceridemic waist (HtgW) phenotype and coronary heart disease (CHD) risk have scarcely been examined. We explored such cardiometabolic risk mediations in middle-aged adults. METHODS: Participants (n = 1924) in a population-based study were studied by forming categories consisting of abdominal obesity, hypertriglyceridemia, both (HtgW), or none ('healthy')...
March 2017: Postgraduate Medicine
Mercè Fernández-Miró, Juan J Chillarón, Mercè Albareda, Sara Fontserè, Cristina Colom, Lluís Vila, Juan Pedro-Botet, Juana A Flores LE-Roux
BACKGROUND: The hypertriglyceridemic waist has been linked to a higher number of cardiovascular risk factors and a greater probability of developing diabetes and cardiovascular disease. Around 50% of individuals with type 1 diabetes (T1D) are overweight or obese and triglyceridemia is associated with the onset of micro- and macrovascular complications. METHODS: A cross-sectional study was conducted in men with T1D to assess the association between the prevalence of hypertriglyceridemic waist and cardiovascular risk factors and hypogonadism...
March 2017: Minerva Endocrinologica
Francieli Barreiro-Ribeiro, Ana Carolina Junqueira Vasques, Cleliani de Cassia da Silva, Mariana Porto Zambon, Ana Maria De Bernardi Rodrigues, Daniella Fernandes Camilo, Maria Ângela Reis de Góes Monteiro Antonio, Ana Raimunda Dâmaso, Raquel Munhoz da Silveira Campos, Sergio Tufik, Marco Túlio de Mello, Bruno Geloneze
OBJECTIVE: This study aimed to identify cutoff points for detecting hypertriglyceridemic waist phenotype (HTWP) in adolescents and to investigate the association of the HTWP with insulin resistance (IR) and metabolic syndrome components. METHODS: A multicentric cross-sectional study of 861 adolescents (10-19 years of age, 504 girls) was conducted. Pubertal stage, anthropometric, and laboratory parameters were assessed. IR was assessed by Homeostasis Model Assessment for Insulin Resistance (HOMA1-IR) index and hyperglycemic clamp (n = 80)...
September 14, 2016: Childhood Obesity
Kang Chen, Ping Li, Yi-Jun Li, Ting Li, Yi-Ming Mu
OBJECTIVE: To investigate the association between hypertriglyceridemic waist (HTGW) phenotype and arterial stiffness in a Chinese population without hypertension, diabetes and cardiovascular diseases. METHODS: A total number of 3028 subjects aged 40 years and over were enrolled in this cross-sectional study. All participants provided a clinical history and underwent a physical examination. Brachial-ankle pulse wave velocity (baPWV) was used to evaluate arterial stiffness...
November 2016: Postgraduate Medicine
Roya Kelishadi, Fahimeh Jamshidi, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Ramin Heshmat, Gelayol Ardalan, Silva Hovsepian
OBJECTIVE: This study aims to investigate the role of metabolic syndrome (MetS) and the hypertriglyceridemic-waist (HW) phenotype in determining cardiometabolic risk factors and elevated liver enzymes in a national sample of Iranian pediatric population. METHOD: This nationwide study was conducted in the framework of the third survey of a surveillance program. Students, aged 10-18 years, were recruited from 27 provinces in Iran. The prevalence of cardiometabolic risk factors was compared in students with and without HW and MetS...
September 2016: Jornal de Pediatria
Ambre Deveaux, Hélène Fouillet, Klaus J Petzke, Dominique Hermier, Etienne André, Pierre Bunouf, Frédérique Lantoine-Adam, Robert Benamouzig, Véronique Mathé, Jean-François Huneau, François Mariotti
BACKGROUND: Oral l-arginine supplements can have a beneficial effect on nitric oxide (NO)-related functions when subjects have cardiovascular disease risk factors. OBJECTIVE: The study was designed to determine the utilization for NO synthesis of oral l-arginine as a function of the cardiometabolic risk and the speed of absorption by comparing immediate-release arginine (IR-Arg), as in supplements, and sustained-release arginine (SR-Arg), which mimics the slow release of dietary arginine...
July 2016: Journal of Nutrition
Yongcheng Ren, Ming Zhang, Jingzhi Zhao, Chongjian Wang, Xinping Luo, Jiatong Zhang, Tian Zhu, Xi Li, Lei Yin, Chao Pang, Tianping Feng, Bingyuan Wang, Lu Zhang, Linlin Li, Xiangyu Yang, Hongyan Zhang, Dongsheng Hu
AIMS/INTRODUCTION: To clarify the association of the hypertriglyceridemic waist phenotype and type 2 diabetes mellitus among adults in China. MATERIALS AND METHODS: In the present case-control study, we included 1,685 patients with type 2 diabetes mellitus and 7,141 normal glucose-tolerant controls from the Henan Province of China in 2011. Elevated waist circumference (GW) was defined as ≥90 cm for men and ≥80 cm for women. Hypertriglyceridemia (HT) was defined as >1...
September 2016: Journal of Diabetes Investigation
Mohsen Janghorbani, Masoud Amini
AIM/INTRODUCTION: We evaluated the association between hypertriglyceridemic waist (HTW) phenotype and the risks of type 2 diabetes in an Iranian high-risk population. MATERIALS AND METHODS: We analyzed 7-year follow-up data (n = 1,865) in non-diabetic first-degree relatives of consecutive patients with type 2 diabetes aged 30-70 years. The primary outcome was the diagnosis of type 2 diabetes based on repeated oral glucose tolerance tests. We used multiple logistic regressions to estimate the odds ratio (OR) for incident type 2 diabetes across four groups according to baseline fasting serum triglycerides (TG) level and waist circumference (WC): normal WC and normal TG, normal WC and high TG, enlarged WC and normal TG, and HTW (enlarged WC high TG)...
November 2016: Journal of Diabetes Investigation
Shuang Chen, Xiaofan Guo, Shasha Yu, Guozhe Sun, Zhao Li, Yingxian Sun
BACKGROUND: The objective was to evaluate the association of the hypertriglyceridemic waist (HTGW) phenotype with prediabetes and diabetes (DM) in rural Chinese population. METHODS: In a cross-sectional study, 11,579 adults (5361 men and 6218 women) aged 35 years or older were recruited from rural areas of China. Anthropometric measurements, laboratory examinations and self-reported information were collected by trained personnel. The HTGW phenotype was defined as elevated triglycerides and elevated waist circumference...
March 25, 2016: International Journal of Environmental Research and Public Health
Abraham Wall-Medrano, Arnulfo Ramos-Jiménez, Rosa P Hernandez-Torres, Rafael Villalobos-Molina, Diana C Tapia-Pancardo, J Rafael Jiménez-Flores, A René Méndez-Cruz, Miguel Murguía-Romero, Itzell A Gallardo-Ortíz, René Urquídez-Romero
BACKGROUND: A body mass index (BMI) ≥30 kg/m(2) and a waist circumference (WC) ≥80 cm in women (WCF) or ≥90 cm in men (WCM) are reference cardiometabolic risk markers (CMM) for Mexicans adults. However, their reliability to predict other CMM (index tests) in young Mexicans has not been studied in depth. METHODS: A cross-sectional descriptive study evaluating several anthropometric, physiological and biochemical CMM from 295 young Mexicans was performed. Sensitivity (Se), specificity (Sp) and Youden's index (J) of reference BMI/WC cutoffs toward other CMM (n = 14) were obtained and their most reliable cutoffs were further calculated at Jmax...
March 8, 2016: BMC Public Health
J Poirier, S Kubow, M Noël, C Dupont, G M Egeland
BACKGROUND AND AIMS: For primary prevention of cardiovascular disease (CVD), Canadian guidelines recommend that asymptomatic Canadians with abdominal obesity undergo Framingham risk score (FRS) assessment, and that in Indigenous Peoples, indicators of metabolic syndrome also be used to identify at-risk individuals. The hypertriglyceridemic-waist phenotype (HTGW) has been proposed to be a surrogate marker of visceral obesity and a simple proxy measure for metabolic syndrome. The primary aim of this study was to evaluate whether the HTGW and the FRS associated with sub-clinical atherosclerosis...
November 2015: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Jesús Millán Núñez-Cortés, Teresa Mantilla Morató, Rocio Toro, Joaquín Millán Pérez, Alipio Mangas Rojas
INTRODUCTION: hypertriglyceridemic waist phenotype has been associated with metabolic syndrome. OBJETIVES: in the present work has been raised to study the relationship between hypertriglyceridemic waist phenotype and metabolic syndrome as well as other metabolic risk factors. And finally, assess whether it is associated with an increased cardiovascular risk. METHODS: this study was conducted recruiting patients in a national registry of hypertriglyceridemia of the Spanish Society of Artherosclerosis...
September 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Anna Ligia Cabral Rocha, Patricia Feliciano Pereira, Milene Cristine Pessoa, Rita de Cassia Gonçalves Alfenas, Wellington Segheto, Danielle Cristina Guimarães da Silva, Marcio Pacheco Andrade, Giana Zarbato Longo
AIMS: the present study aims to evaluate the prevalence of cardiometabolic changes according to the hypertriglyceridemic waist (HW) phenotype in Brazilian adults. METHODS: it is a population based transversal study with 976 adults (n = 533 women) 20-59 years old. Phenotype was defined by triglycerides concentration (TGL) ≥ 150 mg/dl and waist circumference (WC) ≥80 cm in females and ≥ 90 cm in males. All the analyses were adjusted according to the study design and pondered by gender, age and schooling...
September 1, 2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
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