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"hypertriglyceridemic waist phenotype"

Francieli Barreiro-Ribeiro, Ana Carolina Junqueira Vasques, Cleliani de Cassia da Silva, Mariana Porto Zambon, Ana Maria De Bernardi Rodrigues, Daniella Fernandes Camilo, Maria Ângela Reis de Góes Monteiro Antonio, Ana Raimunda Dâmaso, Raquel Munhoz da Silveira Campos, Sergio Tufik, Marco Túlio de Mello, Bruno Geloneze
OBJECTIVE: This study aimed to identify cutoff points for detecting hypertriglyceridemic waist phenotype (HTWP) in adolescents and to investigate the association of the HTWP with insulin resistance (IR) and metabolic syndrome components. METHODS: A multicentric cross-sectional study of 861 adolescents (10-19 years of age, 504 girls) was conducted. Pubertal stage, anthropometric, and laboratory parameters were assessed. IR was assessed by Homeostasis Model Assessment for Insulin Resistance (HOMA1-IR) index and hyperglycemic clamp (n = 80)...
September 14, 2016: Childhood Obesity
Kang Chen, Ping Li, Yijun Li, Ting Li, YiMing Mu
OBJECTIVE: To investigate the association between hypertriglyceridemic waist (HTGW) phenotype and arterial stiffness in a Chinese population without hypertension, diabetes and cardiovascular diseases. METHODS: A total number of 3028 subjects aged 40 years and over were enrolled in this cross-sectional study. All participants provided a clinical history and underwent a physical examination. Brachial-ankle pulse wave velocity (baPWV) was used to evaluate arterial stiffness...
July 19, 2016: Postgraduate Medicine
Roya Kelishadi, Fahimeh Jamshidi, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Ramin Heshmat, Gelayol Ardalan, Silva Hovsepian
OBJECTIVE: This study aims to investigate the role of metabolic syndrome (MetS) and the hypertriglyceridemic-waist (HW) phenotype in determining cardiometabolic risk factors and elevated liver enzymes in a national sample of Iranian pediatric population. METHOD: This nationwide study was conducted in the framework of the third survey of a surveillance program. Students, aged 10-18 years, were recruited from 27 provinces in Iran. The prevalence of cardiometabolic risk factors was compared in students with and without HW and MetS...
September 2016: Jornal de Pediatria
Ambre Deveaux, Hélène Fouillet, Klaus J Petzke, Dominique Hermier, Etienne André, Pierre Bunouf, Frédérique Lantoine-Adam, Robert Benamouzig, Véronique Mathé, Jean-François Huneau, François Mariotti
BACKGROUND: Oral l-arginine supplements can have a beneficial effect on nitric oxide (NO)-related functions when subjects have cardiovascular disease risk factors. OBJECTIVE: The study was designed to determine the utilization for NO synthesis of oral l-arginine as a function of the cardiometabolic risk and the speed of absorption by comparing immediate-release arginine (IR-Arg), as in supplements, and sustained-release arginine (SR-Arg), which mimics the slow release of dietary arginine...
July 2016: Journal of Nutrition
Yongcheng Ren, Ming Zhang, Jingzhi Zhao, Chongjian Wang, Xinping Luo, Jiatong Zhang, Tian Zhu, Xi Li, Lei Yin, Chao Pang, Tianping Feng, Bingyuan Wang, Lu Zhang, Linlin Li, Xiangyu Yang, Hongyan Zhang, Dongsheng Hu
AIMS/INTRODUCTION: To clarify the association of the hypertriglyceridemic waist phenotype and type 2 diabetes mellitus among adults in China. MATERIALS AND METHODS: In the present case-control study, we included 1,685 patients with type 2 diabetes mellitus and 7,141 normal glucose-tolerant controls from the Henan Province of China in 2011. Elevated waist circumference (GW) was defined as ≥90 cm for men and ≥80 cm for women. Hypertriglyceridemia (HT) was defined as >1...
September 2016: Journal of Diabetes Investigation
Mohsen Janghorbani, Masoud Amini
AIM/INTRODUCTION: We evaluated the association between hypertriglyceridemic waist (HTW) phenotype and the risks of type 2 diabetes in an Iranian high-risk population. MATERIALS AND METHODS: We analyzed 7-year follow-up data (n = 1,865) in non-diabetic first-degree relatives of consecutive patients with type 2 diabetes aged 30-70 years. The primary outcome was the diagnosis of type 2 diabetes based on repeated oral glucose tolerance tests. We used multiple logistic regressions to estimate the odds ratio (OR) for incident type 2 diabetes across four groups according to baseline fasting serum triglycerides (TG) level and waist circumference (WC): normal WC and normal TG, normal WC and high TG, enlarged WC and normal TG, and HTW (enlarged WC high TG)...
March 21, 2016: Journal of Diabetes Investigation
Shuang Chen, Xiaofan Guo, Shasha Yu, Guozhe Sun, Zhao Li, Yingxian Sun
BACKGROUND: The objective was to evaluate the association of the hypertriglyceridemic waist (HTGW) phenotype with prediabetes and diabetes (DM) in rural Chinese population. METHODS: In a cross-sectional study, 11,579 adults (5361 men and 6218 women) aged 35 years or older were recruited from rural areas of China. Anthropometric measurements, laboratory examinations and self-reported information were collected by trained personnel. The HTGW phenotype was defined as elevated triglycerides and elevated waist circumference...
April 2016: International Journal of Environmental Research and Public Health
Abraham Wall-Medrano, Arnulfo Ramos-Jiménez, Rosa P Hernandez-Torres, Rafael Villalobos-Molina, Diana C Tapia-Pancardo, J Rafael Jiménez-Flores, A René Méndez-Cruz, Miguel Murguía-Romero, Itzell A Gallardo-Ortíz, René Urquídez-Romero
BACKGROUND: A body mass index (BMI) ≥30 kg/m(2) and a waist circumference (WC) ≥80 cm in women (WCF) or ≥90 cm in men (WCM) are reference cardiometabolic risk markers (CMM) for Mexicans adults. However, their reliability to predict other CMM (index tests) in young Mexicans has not been studied in depth. METHODS: A cross-sectional descriptive study evaluating several anthropometric, physiological and biochemical CMM from 295 young Mexicans was performed. Sensitivity (Se), specificity (Sp) and Youden's index (J) of reference BMI/WC cutoffs toward other CMM (n = 14) were obtained and their most reliable cutoffs were further calculated at Jmax...
2016: BMC Public Health
J Poirier, S Kubow, M Noël, C Dupont, G M Egeland
BACKGROUND AND AIMS: For primary prevention of cardiovascular disease (CVD), Canadian guidelines recommend that asymptomatic Canadians with abdominal obesity undergo Framingham risk score (FRS) assessment, and that in Indigenous Peoples, indicators of metabolic syndrome also be used to identify at-risk individuals. The hypertriglyceridemic-waist phenotype (HTGW) has been proposed to be a surrogate marker of visceral obesity and a simple proxy measure for metabolic syndrome. The primary aim of this study was to evaluate whether the HTGW and the FRS associated with sub-clinical atherosclerosis...
November 2015: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Jesús Millán Núñez-Cortés, Teresa Mantilla Morató, Rocio Toro, Joaquín Millán Pérez, Alipio Mangas Rojas
INTRODUCTION: hypertriglyceridemic waist phenotype has been associated with metabolic syndrome. OBJETIVES: in the present work has been raised to study the relationship between hypertriglyceridemic waist phenotype and metabolic syndrome as well as other metabolic risk factors. And finally, assess whether it is associated with an increased cardiovascular risk. METHODS: this study was conducted recruiting patients in a national registry of hypertriglyceridemia of the Spanish Society of Artherosclerosis...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Anna Ligia Cabral Rocha, Patricia Feliciano Pereira, Milene Cristine Pessoa, Rita de Cassia Gonçalves Alfenas, Wellington Segheto, Danielle Cristina Guimarães da Silva, Marcio Pacheco Andrade, Giana Zarbato Longo
AIMS: the present study aims to evaluate the prevalence of cardiometabolic changes according to the hypertriglyceridemic waist (HW) phenotype in Brazilian adults. METHODS: it is a population based transversal study with 976 adults (n = 533 women) 20-59 years old. Phenotype was defined by triglycerides concentration (TGL) ≥ 150 mg/dl and waist circumference (WC) ≥80 cm in females and ≥ 90 cm in males. All the analyses were adjusted according to the study design and pondered by gender, age and schooling...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Veronica Lucas de Olivera Guattini, Carla Haas Piovesan, Estefânia Wittke, Aline Marcadenti
INTRODUCTION: hypertriglyceridemic waist phenotype (EWET) has been poorly tested in patients with established cardiovascular disease. OBJECTIVES: to evaluate a possible association between EWET, glycidic and lipid profile in patients with newly diagnosed heart attack (HA). METHODS: cross-sectional study among 45 inpatients with myocardial infarction. Lipid profile (total cholesterol, HDL-c, LDL-c, serum triglycerides, TC/HDL-c ratio, non-HDL cholesterol) and glycidic profile (fasting glucose, serum insulin, glycated hemoglobin, HOMA-IR, glucose/insulin ratio) were obtained...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Ricardo Lanzetta Haack, Bernardo Lessa Horta, Denise Petrucci Gigante, Fernando C Barros, Isabel Oliveira, Vera M F Silveira
OBJECTIVE: To evaluate the association of birthweight and weight gain during different periods in childhood with the prevalence of hypertriglyceridemic waist phenotype (HWP). METHODS: In 1982, all hospitals births in Pelotas, South Brazil, were identified, and the 5914 liveborn were examined and their mothers interviewed. This population has been followed for several times. In 2004-05, we tried to follow the whole cohort and the subjects were interviewed, examined, and a blood sample was collected...
2015: PloS One
Zahra Bahadoran, Parvin Mirmiran, Asghar Ghasemi, Fereidoun Azizi
BACKGROUND AND AIM: There are some controversial issues regarding the association of nitric oxide and obesity-related states. This study was conducted to investigate whether serum nitric oxide metabolites (NOx) could predict the occurrence of visceral lipid accumulation, defined as hypertriglyceridemic-waist (HTW) phenotype. METHODS: We used a prospective approach for this study conducted on participants of the Tehran Lipid and Glucose Study, 2243 adult men and women were followed for a median of 6...
August 15, 2015: Nitric Oxide: Biology and Chemistry
D S Buchan, L M Boddy, J-P Despres, F M Grace, N Sculthorpe, C Mahoney, J S Baker
BACKGROUND: It is unclear whether the hypertriglyceridemic waist phenotype (HTWP) can be used to identify those at most risk of cardiometabolic disorders. OBJECTIVES: The utility of the HTWP as a useful predictor of cardiometabolic risk in youth stratified by body mass index was assessed. METHODS: Three hundred and eighty-seven children (12-17.5 years) were used within this cross-sectional study. Participants were classified as normal weight or overweight/obese according to the International Obesity Task Force criteria...
August 2016: Pediatric Obesity
P G Cogate, A J Natali, A de Oliveira, R C Alfenas, H H M Hermsdorff
OBJECTIVE: To assess the potential associations of branched-chain amino acids (BCAA) consumption with central obesity (CObesity) and cardiometabolic risk factors in a population of Brazilian middle-aged men. Special attention was given to leucine intake. DESIGN: Cross-sectional study. SETTING: Universidade Federal de Viçosa, Viçosa, Brazil. PARTICIPANTS: Two-hundred ninety-six middle-aged men (Age: 50.5 ± 5.0 years; Body mass index: 25...
August 2015: Journal of Nutrition, Health & Aging
Jun Huang, Chaomin Zhou, Yongqiang Li, Shuangshuang Zhu, Aiqun Liu, Xiaofei Shao, Xinyu Liu, Harry Holthfer, Hequn Zou
OBJECTIVE: To explore the relationships between visceral adiposity index (VAI), hypertriglyceridemic waist phenotype (HW phenotype) and chronic kidney disease (CKD). METHODS: A cross-sectional study was conducted in Zhuhai City June-October 2012. A total of 2142 participants were recruited. Logistic regression was used to evaluate the associations between VAI, HW phenotype and CKD. RESULTS: After adjustment for age, VAI was significantly associated with CKD (OR 2...
August 2015: International Urology and Nephrology
Byung Sub Moon, Hye-Jeong Park, Min-Kyung Lee, Won Seon Jeon, Se Eun Park, Cheol-Young Park, Won-Yong Lee, Ki-Won Oh, Sung-Woo Park, Eun-Jung Rhee
BACKGROUND: Hypertriglyceridemic waist phenotype is a simple screening parameter to identify people at increased risk for cardiovascular disease. We evaluated whether hypertriglyceridemic waist (HTGW) phenotype increases the risk for coronary artery calcification (CAC) in apparently healthy Korean adults. METHODS: A total of 32,186 participants (mean age 41.3, 80.2% men) in a health screening program, in whom the coronary artery calcium score (CACS) was measured, were analyzed...
September 1, 2015: International Journal of Cardiology
Patrícia Feliciano Pereira, Franciane Rocha de Faria, Eliane Rodrigues de Faria, Helen Hermana Miranda Hermsdorff, Maria do Carmo Gouveia Peluzio, Sylvia do Carmo Castro Franceschini, Silvia Eloiza Priore
OBJECTIVE: To determine the prevalence of metabolic syndrome (MS) and the hypertriglyceridemic waist phenotype (HW) in a representative adolescent sample; as well as to establish which anthropometric indicator better identifies MS and HW, according to gender and adolescent age. METHODS: This cross sectional study had the participation of 800 adolescents (414 girls) from 10-19 years old. Anthropometric indicators (body mass index, waist perimeter, waist/stature ratio, waist/hip ratio, and central/peripheral skinfolds) were determined by standard protocols...
April 2015: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Xiao-li Liu, Fu-zai Yin, Chun-peng Ma, Guo-qin Gao, Chun-ming Ma, Rui Wang, Qiang Lu
OBJECTIVE: The purpose of the present study was to investigate the relationship between waist-to-height ratio (WHtR) and the hypertriglyceridemic waist (HTGW) phenotype to test the hypothesis that WHtR can identify adolescents at high risk of the HTGW phenotype. METHODS: In 2006, anthropometric measurements were assessed in a cross-sectional population-based study of 3136 Han adolescents aged 13-17 years. Blood samples were collected to measure triacylglycerol concentrations...
September 2015: Journal of Pediatric Endocrinology & Metabolism: JPEM
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