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https://www.readbyqxmd.com/read/29457125/enhanced-differentiation-of-dental-pulp-cells-cultured-on-microtubular-polymer-scaffolds-in-vitro
#1
Morteza Haeri, Karen Sagomonyants, Mina Mina, Liisa T Kuhn, A Jon Goldberg
Dental caries (tooth decay) is the most common chronic disease. Dental tissue engineering is a promising alternative approach to alleviate the shortcomings of the currently available restorative materials. Mimicking the natural extracellular matrix (ECM) could enhance the performance of tissue engineering scaffolds. In this study, we developed microtubular (~20 μm diameter) polymethyl methacrylate (PMMA) scaffolds resembling the tubular (~2.5 μm diameter) structure of dentin, the collagen-based mineralized tissue that forms the major portion of teeth, to study the effect of scaffold architecture on differentiation of mouse dental pulp cells in vitro ...
June 2017: Regenerative Engineering and Translational Medicine
https://www.readbyqxmd.com/read/29454320/obesity-and-caries-in-four-to-six-year-old-english-children-a-cross-sectional-study
#2
Martha Paisi, Elizabeth Kay, Irene Kaimi, Robert Witton, Robert Nelder, Ruth Potterton, Debra Lapthorne
BACKGROUND: Obesity and caries are common conditions in childhood and can have significant implications on children's wellbeing. Evidence into their association remains conflicting. Furthermore, studies examining the ssociation between obesity and caries commonly focus on individual-level determinants. The present study aimed to examine the association between obesity and caries in young English children and to determine the impact of deprivation and area-level characteristics on the distribution of the two conditions...
February 17, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29453208/parent-reported-prevalence-and-persistence-of-19-common-child-health-conditions
#3
Tracy Liu, Raghu Lingam, Kate Lycett, Fiona K Mensah, Joshua Muller, Harriet Hiscock, Md Hamidul Huque, Melissa Wake
OBJECTIVE: To estimate prevalence and persistence of 19 common paediatric conditions from infancy to 14-15 years. DESIGN: Population-based prospective cohort study. SETTING: Australia. PARTICIPANTS: Parallel cohorts assessed biennially from 2004 to 2014 from ages 0-1 and 4-5 years to 10-11 and 14-15 years, respectively, in the Longitudinal Study of Australian Children. MAIN OUTCOME MEASURES: 19 health conditions: 17 parent-reported, 2 (overweight/obesity, obesity) directly assessed...
February 16, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29442095/assessment-of-malocclusion-status-dentition-status-and-treatment-needs-among-15-year-old-school-children-of-mangalore
#4
Roshan Shetty, Vijaya Hegde, Pooja J Shetty
Background and Objectives: Dental caries and malocclusion are common dental public health problems. Surveys provide us with an insight into the oral health status and treatment needs and also help in proper treatment planning. Hence, the objective of this study was to assess the malocclusion status, dentition status, and treatment needs of 15-year-old school children of Mangalore. Methodology: A cross-sectional study of 1001 school children aged 15-year-old was conducted in Mangalore...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29436016/identification-of-caries-risk-in-2-year-olds
#5
Tove Irene Wigen, Christine Sophie Baumgartner, Nina Johanne Wang
OBJECTIVE: The first aim was to describe presence of plaque, caries and oral health behaviours in 2-year-old children. The second aim was to measure increments in caries experience from 2 to 5 years of age and to study whether national background, visible plaque, caries and oral health behaviour at 2 years of age were associated with increments in caries experience. METHODS: The study population consisted of 392 children, of whom 211 were monitored from 2 to 5 years of age...
February 13, 2018: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/29435836/oral-and-dental-health-in-head-and-neck-cancer-patients
#6
Joel B Epstein, Andrei Barasch
A diagnosis of head and neck cancer (HNC) is typically followed by therapy that is associated with immediate and long-lasting toxic consequences. HNC patients' oral health needs may be complex and are best addressed in multidisciplinary collaborative teams including surgical, medical, and radiation oncologists, dental providers, nutrition, speech/swallow specialists, and physical therapists. Oral health maintenance also requires patient compliance and caregiver support. The role of dental providers begins prior to cancer diagnosis and continues through survivorship...
2018: Cancer Treatment and Research
https://www.readbyqxmd.com/read/29435491/genomewide-identification-of-essential-genes-and-fitness-determinants-of-streptococcus-mutans-ua159
#7
Robert C Shields, Lin Zeng, David J Culp, Robert A Burne
Transposon mutagenesis coupled with next-generation DNA sequencing (Tn-seq) is a powerful tool for discovering regions of the genome that are required for the survival of bacteria in different environments. We adapted this technique to the dental caries pathogen Streptococcus mutans UA159 and identified 11% of the genome as essential, with many genes encoding products required for replication, translation, lipid metabolism, and cell wall biogenesis. Comparison of the essential genome of S. mutans UA159 with those of selected other streptococci for which such information is available revealed several metabolic pathways and genes that are required in S...
January 2018: MSphere
https://www.readbyqxmd.com/read/29434225/mechanical-stretch-induced-osteogenic-differentiation-of-human-jaw-bone-marrow-mesenchymal-stem-cells-hjbmmscs-via-inhibition-of-the-nf-%C3%AE%C2%BAb-pathway
#8
Xiaoyan Chen, Yuan Liu, Wanghui Ding, Jiejun Shi, Shenglai Li, Yali Liu, Mengjie Wu, Huiming Wang
Severe malocclusion can contribute to several serious dental and physical conditions, such as digestive difficulties, periodontal disease, and severe tooth decay. Orthodontic treatment is mainly used to treat malocclusion. Forces in orthodontic tooth results in bone resorption on the pressure side and bone deposition on the tension side. Osteoblasts have been considered as the key component in bone regeneration on the tension side. However, the underlying mechanisms remain unclear. In this study, we focus on how mechanical stretch regulates the osteogenesis during orthodontic treatment...
February 12, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29422576/neighbourhood-incidence-rate-of-paediatric-dental-extractions-under-general-anaesthetic-in-south-west-england
#9
P J Lucas, D Patsios, K Walls, P Neville, P Harwood, J G Williams, J Sandy
Introduction Extraction of decayed teeth is the most common reason for UK children aged 5-9 years to receive a general anaesthetic. Inequalities in oral health are well recognised, but is under-explored in dental general anaesthesia (DGA).Methods Secondary analysis of routinely collected data from three local authorities in South West England was used to assess: 1) dental activities recorded for children <18 years attending NHS general dental practitioners (GDP); 2) the incidence rate of DGA and disease severity among <16-year-olds; and 3) individual and neighbourhood factors associated with higher rates of child DGA, and greater severity of disease...
February 9, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29415972/synthesis-of-hybrid-copper-chitosan-nanoparticles-with-antibacterial-activity-against-cariogenic-streptococcus-mutans
#10
Cristian Covarrubias, Diego Trepiana, Camila Corral
Hybrid nanoparticles (CuChNP) comprising of copper nanoparticles with a chitosan shell were synthesized. Antimicrobial properties of CuChNP were assessed against Streptococcus mutans (S. mutans), one of the main bacterium that causes tooth decay. Antibacterial activity of CuChNP against S. mutans was comparable to that of oral antimicrobial agents, such as chlorhexidine, and cetylpyridinium chloride. Particularly, CuChNP exhibited superior capacity to prevent the S. mutans growth on human tooth surface as well as disrupt and kill the bacterial cells in an established dental biofilm...
February 8, 2018: Dental Materials Journal
https://www.readbyqxmd.com/read/29412349/dental-caries-in-peoples-of-xingu-indigenous-park-brazil-2007-and-2013
#11
Pablo Natanael Lemos, Douglas Antonio Rodrigues, Paulo Frazão, Clayton Carvalho Coelho, Juliana Nogueira de Souza Campos, Paulo Capel Narvai
OBJECTIVE: to describe the prevalence of dental caries and the supply of dental care in the population of Xingu Indigenous Park, Brazil, at 5, 12 and 15-19 years old, in 2007 and 2013. METHODS: cross-sectional study panel, with secondary data provided by the Indigenous Special Sanitary District of Xingu and Project Xingu. RESULTS: 368 indigenous people were examined in 2007 and 423 in 2013; there was no significant difference between the means of the number of decayed, missing and filled teeth at 5 years (6...
February 1, 2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/29410771/inhibition-of-steptococcus-mutans-biofilm-formation-by-extracts-of-tenacibaculum-sp-20j-a-bacterium-with-wide-spectrum-quorum-quenching-activity
#12
Andrea Muras, Celia Mayer, Manuel Romero, Tamara Camino, Maria D Ferrer, Alex Mira, Ana Otero
Background: Previous studies have suggested the quorum sensing signal AI-2 as a potential target to prevent the biofilm formation by Streptococcus mutans, a pathogen involved in tooth decay. Objective: To obtain inhibition of biofilm formation by S. mutans by extracts obtained from the marine bacterium Tenacibaculum sp. 20J interfering with the AI-2 quorum sensing system. Design: The AI-2 inhibitory activity was tested with the biosensors Vibrio harveyi BB170 and JMH597. S. mutans ATCC25175 biofilm formation was monitored using impedance real-time measurements with the xCELLigence system®, confocal laser microscopy, and the crystal violet quantification method...
2018: Journal of Oral Microbiology
https://www.readbyqxmd.com/read/29405300/evidence-of-effectiveness-of-preventive-dental-care-in-reducing-dental-treatment-use-and-related-expenditures
#13
Nadereh Pourat, Moonkyung Kate Choi, Xiao Chen
OBJECTIVES: Preventive dental health services are intended to reduce the likelihood of development of tooth decay and the need for more intensive treatment overtime. The evidence on the effectiveness of preventive dental care in reducing treatment services and expenditures is lagging for adults, particularly those with lower incomes and chronic conditions. We assessed the impact of preventive dental services on dental treatment service use and expenditures overall and by category of service...
February 6, 2018: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/29402495/effect-of-inhaled-medication-on-dental-caries-index-in-asthmatic-children
#14
Z Bahrololoomi, M H Bemanian, R Ghaffourifard, B Ahmadi
INTRODUCTION: Asthma is a chronic inflammatory disease of airways with a high prevalence among children in pre-school ages. Considering controversial results in different studies about the effect of this disease on the indices of dental caries, the aim of this study was to compare dmft (decay, missing, filling teeth) situation in asthmatic and non-asthmatic 6-12-year-old children. METHODS: This was a case-control study on 46 asthmatic and 47 non-asthmatic children aged 6-12 years...
February 2, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29384297/-an-illustrated-guide-to-dental-screening-a-school-survey
#15
Annabelle Tenenbaum, Mélanie Sayada, Sylvie Azogui-Levy
AIM: Marked social inequalities in oral health are observed right from early childhood. A mandatory complete health check-up, including dental screening, is organized at school for 6-year-old children. School healthcare professionals are not well trained in dental health. The aim of this study was to assess the relevance of an illustrated guide as a simple and rapid dental screening training tool in order to ensure effective, standardized and reproducible screening. METHODS: A cross-sectional study was conducted in the context of the dental examination performed as part of the health check-up...
December 5, 2017: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/29383701/demographic-profile-oral-health-impact-profile-and-dental-anxiety-scale-in-patients-with-chronic-periodontitis-a-case-control-study
#16
Liran Levin, Avraham Zini, Jonathan Levine, Maor Weiss, Ron Lev, Daniella Chebath Taub, Avihai Hai, Galit Almoznino
OBJECTIVES: To examine whether dental anxiety (DA) and oral health-related quality of life (OHRQoL) differ between persons with and those without chronic periodontitis. METHODS: One-hundred patients with chronic periodontitis and 50 age- and- sex-matched controls were included. Data were collected on the following: demographics; smoking habits; Numerical Rating Scale (NRS) for dental pain assessment; Corah's Dental Anxiety Scale (DAS); Oral Health Impact Profile 14 (OHIP-14); Decayed, Missing and Filled Teeth (DMFT) index; Plaque Index (PI); probing depth (PD); bleeding on probing (BOP); and radiographic bone loss...
January 30, 2018: International Dental Journal
https://www.readbyqxmd.com/read/29380853/oral-health-indicators-for-risk-of-malnutrition-in-elders
#17
L L Wu, K Y Cheung, P Y P Lam, X L Gao
OBJECTIVES: Using both clinical parameters and subjective measures of oral health, this study aimed to identify useful oral health indicators for the risk of malnutrition in elders. DESIGN: Cross-sectional study. SETTING: Five community centers run by non-government organizations (NGOs). PARTICIPANTS: 195 community dwelling elders (65 or above). MEASUREMENTS: An interviewer-administered questionnaire was completed to collect information on elders' socio-demographic background and oral health perception and practice...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29380620/parental-oral-health-literacy-of-children-with-severe-early-childhood-caries-in-hong-kong
#18
S Hiu Fong Lai, M Kok Wun Wong, H Ming Wong, C Kar Yung Yiu
AIM: To assess the parental oral health literacy of children with severe early childhood caries. MATERIALS AND METHODS: A total of 315 children diagnosed with severe early childhood caries, and their parents were recruited to participate in the study. A clinical examination was conducted to assess the children's oral health status. Their parents were asked to complete a Hong Kong Oral Health Literacy Assessment Task for Paediatric Dentistry (HKOHLAT-P) questionnaire...
December 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29380611/evaluation-of-the-relationship-between-obesity-dental-caries-and-periodontal-disease-in-adolescents
#19
G Vallogini, V Nobili, R Rongo, S De Rosa, F Magliarditi, V D'Antò, A Galeotti
AIM: To assess the prevalence of caries, oral hygiene quality and periodontal disease in a cohort of obese adolescents compared to a control group. MATERIALS AND METHODS: Study Design: cross-sectional study conducted on 204 subjects (age range 10-16 years). Ninety obese subjects (BMI >90) and 114 normal-weight subjects (BMI <75) were visited at the Bambino Gesù Children's Hospital and in a junior high school in Rome, respectively. An ad hoc questionnaire (investigating demographic and oral health behaviour data) was filled in by patients and their caregivers...
December 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29379311/postoperative-discomfort-and-emergence-delirium-in-children-undergoing-dental-rehabilitation-under-general-anesthesia-comparison-of-nasal-tracheal-intubation-and-laryngeal-mask-airway
#20
Sultan Keles, Ozlem Kocaturk
Background: Several studies have identified side effects of general anesthesia with endotracheal intubation, such as laryngeal pain, dysphonia, and postoperative nausea and vomiting (PONV). The laryngeal mask airway (LMAw) is believed to decrease these side effects. The aim of this trial was to compare postoperative discomfort, emergence delirium, and recovery time of patients who received either an LMAw or nasotracheal intubation (NTI). Patients and methods: A total of 70 children were randomly assigned to the LMAw group (n=35) or the NTI group (n=35)...
2018: Journal of Pain Research
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