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https://www.readbyqxmd.com/read/29191891/bone-voyage-osteoblasts-remotely-control-tumors
#1
COMMENT
Haiying Zhang, David Lyden
No abstract text is available yet for this article.
December 1, 2017: Science
https://www.readbyqxmd.com/read/29180516/the-egfr-odyssey-from-activation-to-destruction-in-space-and-time
#2
REVIEW
Jeroen Bakker, Menno Spits, Jacques Neefjes, Ilana Berlin
When cell surface receptors engage their cognate ligands in the extracellular space, they become competent to transmit potent signals to the inside of the cell, thereby instigating growth, differentiation, motility and many other processes. In order to control these signals, activated receptors are endocytosed and thoroughly curated by the endosomal network of intracellular vesicles and proteolytic organelles. In this Review, we follow the epidermal growth factor (EGF) receptor (EGFR) from ligand engagement, through its voyage on endosomes and, ultimately, to its destruction in the lysosome...
November 27, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29162205/gastroenteritis-outbreaks-on-cruise-ships-contributing-factors-and-thresholds-for-early-outbreak-detection
#3
Varvara A Mouchtouri, Eleni Verykouki, Dumitru Zamfir, Christos Hadjipetris, Hannah C Lewis, Christos Hadjichristodoulou, The Eu Shipsan Act Partnership
When an increased number of acute gastroenteritis (AG) cases is detected among tourists staying at the same accommodation, outbreak management plans must be activated in a timely manner to prevent large outbreaks. Syndromic surveillance data collected between 1 January 2010 and 31 December 2013 by five seagoing cruise ships were analysed to identify attack rate thresholds for early outbreak detection. The overall incidence rate of AG was 2.81 cases per 10,000 traveller-days (95% confidence interval (CI): 0...
November 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29146200/on-board-measurements-of-particle-and-gaseous-emissions-from-a-large-cargo-vessel-at-different-operating-conditions
#4
Thuy Chu-Van, Zoran Ristovski, Ali Mohammad Pourkhesalian, Thomas Rainey, Vikram Garaniya, Rouzbeh Abbassi, Sanaz Jahangiri, Hossein Enshaei, U-Shen Kam, Richard Kimball, Liping Yang, Ali Zare, Harry Bartlett, Richard J Brown
This study investigated particle and gaseous emission factors from a large cargo vessel for her whole voyage including at berth, manoeuvring and cruising. Quantification of these factors assists in minimising the uncertainty in the current methods of exhaust gas emission factor estimation. Engine performance and emissions from the main marine engine were measured on-board while the ship was manoeuvring and cruising at sea. Emissions of an auxiliary engine working at 55% of maximum continuous rating (MCR) were measured when the ship was at actual harbour stopovers...
November 13, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29119771/-the-crisis-of-science-and-democracy-a-voyage-to-a-destination-not-yet-revealed
#5
Bruna De Marchi, Silvio Funtowicz
No abstract text is available yet for this article.
September 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/29060703/brainwatch-software-for-interactive-exploration-of-brain-scans-in-3d-virtual-reality-systems
#6
S Koby Taswell, Teja Veeramacheneni, Carl Taswell
The ability to view medical images as 3D objects, which can be explored interactively, has now become possible due to the advent of rapidly emerging virtual reality (VR) technologies. In the past, VR has been used as an educational tool for learning anatomy, a visualization tool for assisting surgery, and a therapeutic tool for rehabilitating patients with motor disorders. However, these older systems were either expensive to build or difficult to acquire and use. Exploiting the arrival of new consumer devices such as the Oculus Rift that are now affordable, we have developed a software application called BrainWatch for VR ready computers to enable 3D visualization and interactive exploration of DICOM data sets focusing on PET and MRI brain scans...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29047582/composite-infrared-spectrometer-cirs-on-cassini
#7
D E Jennings, F M Flasar, V G Kunde, C A Nixon, M E Segura, P N Romani, N Gorius, S Albright, J C Brasunas, R C Carlson, A A Mamoutkine, E Guandique, M S Kaelberer, S Aslam, R K Achterberg, G L Bjoraker, C M Anderson, V Cottini, J C Pearl, M D Smith, B E Hesman, R D Barney, S Calcutt, T J Vellacott, L J Spilker, S G Edgington, S M Brooks, P Ade, P J Schinder, A Coustenis, R Courtin, G Michel, R Fettig, S Pilorz, C Ferrari
The Cassini spacecraft orbiting Saturn carries the composite infrared spectrometer (CIRS) designed to study thermal emission from Saturn and its rings and moons. CIRS, a Fourier transform spectrometer, is an indispensable part of the payload providing unique measurements and important synergies with the other instruments. It takes full advantage of Cassini's 13-year-long mission and surpasses the capabilities of previous spectrometers on Voyager 1 and 2. The instrument, consisting of two interferometers sharing a telescope and a scan mechanism, covers over a factor of 100 in wavelength in the mid and far infrared...
June 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/29042713/trivial-molecules-may-prevent-or-hamper-tooth-decay-a-potential-voyaged
#8
EDITORIAL
S G Damle
No abstract text is available yet for this article.
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28990466/task-dependent-cold-stress-during-expeditions-in-antarctic-environments
#9
Drew M Morris, June J Pilcher, Robert B Powell
This study seeks to understand the degree of body cooling, cold perception and physical discomfort during Antarctic tour excursions. Eight experienced expedition leaders across three Antarctic cruise voyages were monitored during occupational tasks: kayaking, snorkelling and zodiac outings. Subjective cold perception and discomfort were recorded using a thermal comfort assessment and skin temperature was recorded using a portable data logger. Indoor cabin temperature and outdoor temperature with wind velocity were used as measures of environmental stress...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28983042/a-fantastic-voyage-in-genomics
#10
Laura M Zahn
No abstract text is available yet for this article.
October 6, 2017: Science
https://www.readbyqxmd.com/read/28968434/data-reconstruction-can-improve-abundance-index-estimation-an-example-using-taiwanese-longline-data-for-pacific-bluefin-tuna
#11
Shui-Kai Chang, Hung-I Liu, Hiromu Fukuda, Mark N Maunder
Catch-per-unit-effort (CPUE) is often the main piece of information used in fisheries stock assessment; however, the catch and effort data that are traditionally compiled from commercial logbooks can be incomplete or unreliable due to many reasons. Pacific bluefin tuna (PBF) is a seasonal target species in the Taiwanese longline fishery. Since 2010, detailed catch information for each PBF has been made available through a catch documentation scheme. However, previously, only market landing data with a low coverage of logbooks were available...
2017: PloS One
https://www.readbyqxmd.com/read/28940259/efficacy-of-guselkumab-in-subpopulations-of-patients-with-moderate-to-severe-plaque-psoriasis-a-pooled-analysis-of-the-phase-3-voyage-1-and-voyage-2-studies
#12
K B Gordon, A Blauvelt, P Foley, M Song, Y Wasfi, B Randazzo, Y K Shen, Y You, C E M Griffiths
OBJECTIVES: To evaluate the efficacy of guselkumab in patient subgroups with moderate-to-severe psoriasis from the pooled guselkumab VOYAGE 1 and VOYAGE 2 Phase 3 studies. METHODS: Using data from the pooled VOYAGE 1 and VOYAGE 2 psoriasis studies, analyses were performed to evaluate the consistency of efficacy (Investigator's Global Assessment [IGA] 0/1 [cleared or minimal psoriasis] and IGA 0 [cleared]) across subpopulations defined by demographics, baseline disease characteristics, and previous psoriasis treatment...
September 22, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28931133/a-descriptive-study-of-advising-practices-during-travel-health-consultations-in-france
#13
C Marchand, F Merrina, R Gagnayre, O Bouchaud
Background: Recommendations for improving traveler adherence address both the content of the advice given and the structure of the consultation. The objective of this article is to describe how travel health consultations are structured in France. Methods: A questionnaire based on both theoretical foundations and recommendations in the literature was sent to health professionals who practice in travel clinics, all of them members of France's Société de Médecine des Voyages...
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28863328/effects-of-age-gender-and-statin-dose-on-lipid-levels-results-from-the-voyager-meta-analysis-database
#14
Björn W Karlson, Michael K Palmer, Stephen J Nicholls, Philip J Barter, Pia Lundman
BACKGROUND AND AIMS: The effectiveness of statins in the treatment of dyslipidaemia and reduction of cardiovascular risk is well established. However, the association of statin-mediated lipid effects with age and gender is unclear. This study aimed to determine whether age and gender are associated with statin-mediated changes in low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and non-HDL-C. METHODS: Individual patient data (n = 32,258) were obtained from VOYAGER...
August 19, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28836599/space-science-voyager-at-40
#15
Alexandra Witze
No abstract text is available yet for this article.
August 23, 2017: Nature
https://www.readbyqxmd.com/read/28757485/francis-bacon-s-i-valerius-terminus-i-and-the-voyage-to-the-great-instauration
#16
Richard Serjeantson
Francis Bacon's earliest surviving natural philosophical treatise (composed circa 1603) bears the title Valerius Terminus of the Interpretation of Nature. This study, resting on fresh attention to the surviving authorial manuscript, has three goals. It begins by identifying a lost precursor work apparently entitled "Of Active Knowledge." It then examines the significance of the pseudonyms Bacon chose to introduce his ideas, considering especially his invocation of Erasmus's emblem, the Roman deity Terminus...
2017: Journal of the History of Ideas
https://www.readbyqxmd.com/read/28753364/novel-cosmic-ray-electron-and-positron-constraints-on-mev-dark-matter-particles
#17
Mathieu Boudaud, Julien Lavalle, Pierre Salati
MeV dark matter (DM) particles annihilating or decaying to electron-positron pairs cannot, in principle, be observed via local cosmic-ray (CR) measurements because of the shielding solar magnetic field. In this Letter, we take advantage of spacecraft Voyager 1's capacity for detecting interstellar CRs since it crossed the heliopause in 2012. This opens up a new avenue to probe DM in the sub-GeV energy/mass range that we exploit here for the first time. From a complete description of the transport of electrons and positrons at low energy, we derive predictions for both the secondary astrophysical background and the pair production mechanisms relevant to DM annihilation or decay down to the MeV mass range...
July 14, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28743677/maiden-voyage-of-the-collaborative-cross-mouse-exploring-variability-in-animals-response-to-perchloroethylene
#18
Charles W Schmidt
No abstract text is available yet for this article.
July 24, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28741379/tiny-rnas-and-their-voyage-via-extracellular-vesicles-secretion-of-bacterial-small-rna-and-eukaryotic-microrna
#19
REVIEW
Ji-Woong Choi, Jee-Hyun Um, Jin-Hyun Cho, Heon-Jin Lee
MicroRNAs are small non-coding RNAs that bind to the 3'-untranslated region of target mRNAs and have transcriptional or translational inhibitory function in eukaryotes. Before microRNAs were widely known, bacterial non-coding small RNAs around 50-200 nt in length were discovered whose mechanism of action resembled that of microRNAs. Recently, RNAs that are of similar size to or smaller than microRNAs have been discovered in bacteria and indeed, this class of small RNAs have been found throughout all domains of life...
September 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28691800/three-lessons-for-the-microplastics-voyage
#20
David Sedlak
No abstract text is available yet for this article.
July 10, 2017: Environmental Science & Technology
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