keyword
https://read.qxmd.com/read/38537312/small-fiber-neuropathy-in-children-adolescents-and-young-adults-with-chronic-orthostatic-intolerance-and-postural-orthostatic-tachycardia-syndrome-a-retrospective-study
#21
JOURNAL ARTICLE
Jeffrey P Moak, Carolyn B Ramwell, Heather Gordish-Dressman, Sangeeta D Sule, Elizabeth Bettini
PURPOSE: To determine in children, adolescent and young adult (CAYA) patients presenting with Orthostatic Intolerance (OI) or Postural Orthostatic Tachycardia Syndrome (POTS) associated with the additional symptoms of neuropathic discomfort (pain, paresthesia and/or allodynia): 1) the incidence of small fiber neuropathy, and 2) assess if there was serologic evidence for an underlying inflammatory or autoimmune state. METHODS: A cohort of 109 CAYA patients with the above symptoms underwent epidermal skin biopsy for nerve fiber density...
March 8, 2024: Autonomic Neuroscience: Basic & Clinical
https://read.qxmd.com/read/38536861/predictors-for-participation-in-mass-treatment-and-female-genital-schistosomiasis-re-investigation-and-the-effect-of-praziquantel-treatment-in-south-african-adolescents
#22
JOURNAL ARTICLE
Takalani Girly Nemungadi, Elisabeth Kleppa, Hashini Nilushika Galappaththi-Arachchige, Pavitra Pillay, Svein Gunnar Gundersen, Birgitte Jyding Vennervald, Patricia Doris Ndhlovu, Myra Taylor, Saloshni Naidoo, Eyrun Floerecke Kjetland
OBJECTIVE: Female Genital Schistosomiasis (FGS) causes intravaginal lesions and symptoms that could be mistaken for sexually transmitted diseases or cancer. In adults, FGS lesions [grainy sandy patches (GSP), homogenous yellow patches (HYP), abnormal blood vessels and rubbery papules] are refractory to treatment. The effect of treatment has never been explored in young women; it is unclear if gynaecological investigation will be possible in this young age group (16-23 years). We explored the predictors for accepting anti-schistosomal treatment and/or gynaecological reinvestigation in young women, and the effects of anti-schistosomal mass-treatment (praziquantel) on the clinical manifestations of FGS at an adolescent age...
March 27, 2024: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/38536600/characterizing-use-of-supervised-consumption-services-among-street-involved-youth-and-young-adults-in-the-context-of-an-overdose-crisis
#23
JOURNAL ARTICLE
Kiera Lee-Pii, Kora DeBeck, JinCheol Choi, Kali-Olt Sedgemore, Thomas Kerr, Mary Clare Kennedy
In response to an increase in overdose deaths, there was a rapid scale-up of supervised consumption services (SCS), including federally sanctioned SCS and low-barrier SCS known as overdose prevention sites (OPS), in Vancouver, Canada, beginning in December 2016. However, little is known about the use of such services among adolescents and young adults (AYA) in this context. We therefore sought to characterize factors associated with the use of federally sanctioned SCS and OPS among street-involved AYA who inject drugs in Vancouver during an overdose crisis...
March 27, 2024: Journal of Urban Health
https://read.qxmd.com/read/38535514/pediatric-lemierre-s-syndrome-a-comprehensive-literature-review
#24
REVIEW
Salvatore Lavalle, Edoardo Masiello, Salvatore Cocuzza, Piero Pavone, Alessandra Di Nora, Christian Calvo-Henriquez, Jerome Rene Lechien, Miguel Mayo Yanez, Andrea Praticò, Manuela Ceccarelli, Giannicola Iannella, Annalisa Pace, Federica Maria Parisi, Giuseppe Magliulo, Antonino Maniaci
BACKGROUND: Lemierre syndrome is a rare, potentially fatal complication of oropharyngeal infections characterized by septic thrombophlebitis of the internal jugular vein. It primarily affects healthy adolescents and young adults. Its incidence declined after the antibiotic era, but it may have resurged in recent decades, likely due to judicious antibiotic use and increasing bacterial resistance. Prompt diagnosis and treatment are imperative to prevent significant morbidity and mortality...
March 18, 2024: Pediatric Reports
https://read.qxmd.com/read/38534928/adapting-an-adolescent-and-young-adult-program-housed-in-a-quaternary-cancer-centre-to-a-regional-cancer-centre-creating-equitable-access-to-developmentally-tailored-support
#25
JOURNAL ARTICLE
Marlie Smith, Simone Kurup, Kaviya Devaraja, Shaayini Shanawaz, Lorrie Reynolds, Jill Ross, Andrea Bezjak, Abha A Gupta, Alisha Kassam
Adolescents and young adults (AYAs) with cancer, representing those between 15 and 39 years of age, face distinctive challenges balancing their life stage with the physical, emotional, and social impacts of a cancer diagnosis. These challenges include fertility concerns, disruptions to educational and occupational pursuits, issues related to body image and sexual health, and the need for age-appropriate psychosocial support within their communities. The Princess Margaret Cancer Centre (PM), a quaternary care center, established a specialized AYA program in 2014, offering holistic and developmentally tailored psychosocial support and currently, efforts are underway to expand this to other regions in the province to address the need for equitable access...
February 27, 2024: Current Oncology
https://read.qxmd.com/read/38534905/alexithymia-as-a-risk-factor-for-an-internet-addiction-in-adolescents-and-young-adults-with-autism-spectrum-disorder
#26
JOURNAL ARTICLE
Magdalena Anna Skotalczyk, Karolina Anna Dąbrowska, Joanna Smorońska-Rypel, Krzysztof Maria Wilczyński, Małgorzata Janas-Kozik
The aim of the study is to investigate the association of alexithymia with Internet addiction and autism spectrum disorders among adolescents and young adults. The links between alexithymia, ASD and other mental disorders are still a largely unexplored topic in psychiatry. An intriguing question is to what extent alexithymia can be a component of the clinical picture of ASD, and to what extent it is an independent phenomenon often co-occurring with ASD. The study group consisted of young Poles aged 11 to 35 ( n = 229), including women ( n = 167; 73%), men ( n = 53; 23%) and non-binary people ( n = 9; 4%)...
March 12, 2024: European journal of investigation in health, psychology and education
https://read.qxmd.com/read/38533787/adaptive-to-maladaptive-gradient-of-emotion-regulation-tendencies-are-embedded-in-the-functional-structural-hybrid-connectome
#27
JOURNAL ARTICLE
Wonyoung Kim, M Justin Kim
BACKGROUND: Emotion regulation tendencies are well-known transdiagnostic markers of psychopathology, but their neurobiological foundations have mostly been examined within the theoretical framework of cortical-subcortical interactions. METHODS: We explored the connectome-wide neural correlates of emotion regulation tendencies using functional and diffusion magnetic resonance images of healthy young adults ( N = 99; age 20-30; 28 females). We first tested the importance of considering both the functional and structural connectome through intersubject representational similarity analyses...
March 27, 2024: Psychological Medicine
https://read.qxmd.com/read/38533276/primary-hyperparathyroidism-in-young-and-adolescents-alike-or-unlike-adult-hyperparathyroidism-a-series-from-south-india
#28
JOURNAL ARTICLE
Dhalapathy Sadacharan, Smitha S Rao, Shriraam Mahadevan, G Shanmugasundar, S Murthy, Shruti Chandrashekaran, Vijay Bhaskar Reddy, Bharath Ramji
BACKGROUND: Primary hyperparathyroidism (PHPT) is a common endocrine condition but rare in the pediatric and adolescent populations. The presentations can be unique, accounting for significant morbidity in the case of untimely detection. AIM: To study surgically treated pediatric PHPT retrospectively. METHODS: Surgically treated children of PHPT up to 20 years of age between 2010 to 2022 were analyzed. All of them were operated on by an endocrine surgeon and team...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38532574/comparison-of-the-skindex-teen-and-the-skindex-29-quality-of-life-survey-instruments-in-a-predominantly-american-indian-adolescent-population
#29
JOURNAL ARTICLE
Micah G Pascual, Sarah J Schmiege, Spero M Manson, Lucinda L Kohn
BACKGROUND/OBJECTIVES: The Skindex-29 and Skindex-Teen assess dermatology-related quality of life among adults and adolescents, respectively. This study directly compared the same adolescents' responses to the Skindex-29 relative to Skindex-Teen in a predominantly American Indian and/or Alaska Native population. This population is underrepresented in medical research. Although skin-related quality-of-life issues are widespread, American Indian and/or Alaska Native adolescents are not well-represented in related studies...
March 26, 2024: Pediatric Dermatology
https://read.qxmd.com/read/38532465/bulk-rna-sequencing-for-analysis-of-post-covid-19-condition-in-adolescents-and-young-adults
#30
JOURNAL ARTICLE
Silke Lauren Sommen, Zhi Zhao, Sunniva Segtnan, Tonje Stiansen-Sonerud, Joel Selvakumar, Lise Beier Havdal, Johannes Gjerstad, Vegard Bruun Bratholm Wyller, Lise Lund Berven
BACKGROUND: Post COVID-19 condition (PCC) is a complication of SARS-COV-2 infection and can lead to long-term disability. METHODS: The present study was designed to analyse the gene expression patterns of PCC through bulk RNA sequencing of whole blood and to explore the potential molecular mechanisms of PCC. Whole blood was collected from 80 participants enrolled in a prospective cohort study following SARS-CoV-2 infected and non-infected individuals for 6 months after recruitment and was used for bulk RNA sequencing...
March 26, 2024: Journal of Translational Medicine
https://read.qxmd.com/read/38531612/individual-outcomes-after-tailored-versus-generic-self-management-strategies-for-persistent-fatigue-in-youth-with-a-fatigue-syndrome-or-rheumatic-condition-a-multiple-single-case-study
#31
JOURNAL ARTICLE
Anouk Vroegindeweij, Jan Houtveen, Desiree A Lucassen, Elise M Van De Putte, Nico M Wulffraat, Sanne L Nijhof, Joost F Swart
OBJECTIVE: To examine individual outcomes after tailored lifestyle (PROfeel) or generic dietary advice as self-management intervention for persistent fatigue in adolescents and young adults with a chronic condition, to compare participants who did and did not benefit and to explore changes to factors in the biopsychosocial model of fatigue after PROfeel. METHOD: A multiple single-case AB-phase design was embedded in a randomized crossover trial (N = 45)...
March 26, 2024: British Journal of Health Psychology
https://read.qxmd.com/read/38531533/2023-obesity-fact-sheet-prevalence-of-obesity-and-abdominal-obesity-in-adults-adolescents-and-children-in-korea-from-2012-to-2021
#32
JOURNAL ARTICLE
Su-Min Jeong, Jin-Hyung Jung, Ye Seul Yang, Wonsock Kim, In Young Cho, You-Bin Lee, Kye-Yeung Park, Ga Eun Nam, Kyungdo Han
BACKGROUND: The 2023 Obesity Fact Sheet aims to present an updated overview of obesity prevalence across all age groups, including children and adolescents. METHODS: This study included individuals aged ≥20 years who underwent health checkups provided by the Korean National Health Insurance Service between 2012 and 2021. The prevalence of obesity and abdominal obesity was standardized by age and sex using data from the 2010 population and housing census. For children and adolescents (6 to 18 years), we used the Korea National Health and Nutrition Examination Survey (2012 to 2021), and obesity was defined by the corresponding sex- and age-specific body mass index percentile of 95th or greater based on the 2017 Korean National Growth Chart for Children and Adolescents...
March 27, 2024: Journal of obesity & metabolic syndrome
https://read.qxmd.com/read/38531508/patient-and-provider-medication-preferences-affect-treatment-outcomes-among-adolescents-and-young-adults-with-opioid-use-disorder
#33
JOURNAL ARTICLE
Laura B Monico, Jesse B Fletcher, Tyler Ross, Robert P Schwartz, Marc J Fishman, Jan Gryczynski, Shannon Gwin Mitchell
BACKGROUND: The opioid epidemic in the United States has not spared youth or young adults, as evidenced by a six-fold increase in opioid use disorder (OUD) diagnoses in the last two decades. Given this dramatic rise, a call for greater uptake and accessibility of medications for opioid use disorder (MOUDs) among youth and young adults has ensued, resulting in an increasing number of MOUD treatment pathways for this vulnerable population. METHODS: This secondary data analysis seeks to characterize patient and provider preferences for MOUD treatment pathways, and test for associations between baseline MOUD treatment preferences and opioid use and treatment adherence outcomes...
March 24, 2024: J Subst Use Addict Treat
https://read.qxmd.com/read/38531425/adolescent-activity-based-anorexia-has-a-substantial-and-prolonged-impact-on-social-behavior-in-young-adult-female-rats
#34
JOURNAL ARTICLE
Melinda Karth, Kimberly Kinzig
Activity-based anorexia (ABA) is a rodent model of anorexia nervosa (AN) that induces several key components of AN, including voluntary reduction in food intake, reduced body weight, hyperactivity, and alterations to the hypothalamic-pituitary-adrenal (HPA) axis. Previous research has demonstrated persistently increased anxiety-like behavior in the elevated plus maze (EPM), a test measuring avoidance of novel and open areas in adult female rats that experienced ABA during adolescence and are weight-restored in adulthood...
March 24, 2024: Physiology & Behavior
https://read.qxmd.com/read/38531294/young-carers-supporting-a-relative-with-cancer-what-is-the-healthcare-professionals-knowledge-in-france-an-exploratory-study
#35
REVIEW
Pauline Justin, Géraldine Dorard, Agnes Leu, Aurélie Untas
PURPOSE: Many children and adolescents support relatives with cancer. However, literature about young carers (YCs) shows a lack of awareness among professionals, especially in oncology. This quantitative study aims to explore the level of knowledge and perceptions of healthcare professionals working with cancer patients about the situations and characteristics of YCs. METHODS: 395 professionals participated in an online survey. Professionals reported sociodemographic and professional information and answered several questions evaluating their perceptions about YCs, such as the types of support provided and the consequences of being a YC...
March 18, 2024: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://read.qxmd.com/read/38530870/mother-child-closeness-and-adult-children-s-time-and-financial-assistance
#36
JOURNAL ARTICLE
I-Fen Lin, Anna M Hammersmith
OBJECTIVE: Drawing on the intergenerational solidarity framework and life course perspective, the authors assessed how mother-child closeness across different life stages is associated with adult children's time and financial assistance to mothers in later life. METHOD: Using children's reports of their perceived closeness to mothers from waves 1 to 4 of the National Longitudinal Study of Adolescent to Adult Health (Add Health) and mothers' reports about adult children's time and financial assistance from wave 2 of the Add Health Parent Study (AHPS) in the United States, the authors investigated how mother-child closeness during adolescence, emerging adulthood, and young adulthood is related to midlife adult children's support with a focus on difference between mother-daughter (N = 934) and mother-son (N = 899) dyads...
March 26, 2024: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://read.qxmd.com/read/38529528/juveniles-young-adults-and-infants-with-hepatitis-b-virus-infection-a-genomic-study
#37
JOURNAL ARTICLE
Hanwen Zhang, Meina Li, Huijuan Liu, Yi Dong, Weijie Li, Pan Zhao
Integration of hepatitis B virus (HBV) DNA into the human genome is recognized as an oncogenic factor and a barrier to hepatitis B cure. In the study, biopsy liver tissues were collected from adolescents and young adults with acute HBV infection younger than or equal to 35 years of age and from HBV-infected infant patients younger than or equal to 6 months of age. A high-throughput sequencing method was used to detect HBV DNA integration. Totally, 12 adolescents, young adults, and 6 infants were included. Among the 12 patients with acute HBV infection, immunohistochemical staining of intrahepatic hepatitis B surface antigen for all displayed negative results, and no HBV DNA integrants in the hepatocyte DNA were confirmed...
March 2024: Journal of Medical Virology
https://read.qxmd.com/read/38529082/identification-of-psychosis-risk-and-diagnosis-of-first-episode-psychosis-advice-for-clinicians
#38
REVIEW
Nancy B Lundin, Alexandra M Blouin, Henry R Cowan, Aubrey M Moe, Heather M Wastler, Nicholas J K Breitborde
Early detection of psychotic-spectrum disorders among adolescents and young adults is crucial, as the initial years after psychotic symptom onset encompass a critical period in which psychosocial and pharmacological interventions are most effective. Moreover, clinicians and researchers in recent decades have thoroughly characterized psychosis-risk syndromes, in which youth are experiencing early warning signs indicative of heightened risk for developing a psychotic disorder. These insights have created opportunities for intervention even earlier in the illness course, ideally culminating in the prevention or mitigation of psychosis onset...
2024: Psychology Research and Behavior Management
https://read.qxmd.com/read/38528292/global-burden-and-trends-of-acute-viral-hepatitis-among-children-and-adolescents-from-1990-to-2019-a-systematic-analysis-of-the-global-burden-of-disease-study-2019
#39
JOURNAL ARTICLE
Wanglong Xiao, Jingwei Zhao, Yiwen Chen, Xingzhu Liu, Chang Xu, Jiaxu Zhang, Yongbing Qian, Qiang Xia
BACKGROUND: Children and adolescents are at high risk for acute viral hepatitis (AVH), but epidemiological research focusing on them has been overshadowed by adult chronic B and C. We provide global, regional, and national estimates of the AVH burden and their trends on people under 20 years from 1990 to 2019. METHODS: AVH data from Global Burden of Disease Study (GBD) 2019 was used. Incidence and disability-adjusted life years (DALYs) were calculated, analyzing trends with estimated annual percentage change (EAPC) and Joinpoint regression...
March 26, 2024: Hepatology International
https://read.qxmd.com/read/38528215/poverty-and-birth-cohort-effects-of-experiencing-the-2007-2009-great-recession-during-adolescence-on-major-depressive-episodes-and-mental-health-treatment-of-young-adults-in-the-united-states
#40
JOURNAL ARTICLE
Melanie S Askari, Daniel W Belsky, Mark Olfson, Ramin Mojtabai, Joshua Breslau, Katherine M Keyes
PURPOSE: Household economic adversity during adolescence is hypothesized to be a risk factor for poor mental health later in life. To test this hypothesis, we conducted a quasi-experimental analysis of an economic shock, the Great Recession of 2007-2009. We tested if going through adolescence during the Great Recession was associated with increased risk of major depressive episodes (MDE) and mental health treatment in young adulthood with potential moderation by household poverty to explore differences by economic adversity...
March 26, 2024: Social Psychiatry and Psychiatric Epidemiology
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