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https://www.readbyqxmd.com/read/28922575/the-hospital-anxiety-and-depression-scale-factor-structure-and-psychometric-properties-in-older-adolescents-and-young-adults-with-autism-spectrum-disorder
#1
Mirko Uljarević, Amanda L Richdale, Helen McConachie, Darren Hedley, Ru Ying Cai, Hannah Merrick, Jeremy R Parr, Ann Le Couteur
Despite the high frequency of anxiety and depression symptoms in individuals with Autism Spectrum Disorder (ASD) and a significant impact of these comorbidities on both individuals with ASD and their families, research on the validity of anxiety and depression measures in the ASD population is currently lacking. The aim of this study was to explore the psychometric properties of the Hospital Anxiety and Depression Scale [HADS; Zigmond & Snaith, ] in a sample of older adolescents and young adults with ASD. One hundred and fifty one participants (UK Transition longitudinal study: N = 106; 75 males, Mage  = 16...
September 18, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28920971/-dental-erosion-and-young-adults-what-do-they-know-and-how-would-they-like-to-receive-information
#2
V J N Verploegen, A A Schuller
Dental erosion occurs often among adolescents and young adults in the Netherlands. This problem requires attention because its consequences are irreversible. In this study (part of the 'Dental Research and Practice in the North Netherlands' project) a questionnaire was distributed to 331 young adults (age 20 to 25) from 25 dental practices. The goal of the study was to find out how much young adults know about dental erosion and how they wish to receive dental information. The results show that much is still unknown about dental erosion among young adults and that the extent of knowledge depended of the level of education and on information on dental erosion that had already been received...
September 2017: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/28920011/perceived-racial-ethnic-discrimination-and-mental-health-a-review-and-future-directions-for-social-epidemiology
#3
Anissa I Vines, Julia B Ward, Evette Cordoba, Kristin Z Black
PURPOSE OF REVIEW: Recent literature on racial or ethnic discrimination and mental health was reviewed to assess the current science and identify key areas of emphasis for social epidemiology. Objectives of this review were to: 1) Determine whether there have been advancements in the measurement and analysis of perceived discrimination; 2) Identify the use of theories and/or frameworks in perceived discrimination and mental health research; and 3) Assess the extent to which stress buffers are being considered and evaluated in the existing literature...
June 2017: Current Epidemiology Reports
https://www.readbyqxmd.com/read/28919875/psychological-support-for-young-adults-with-down-syndrome-dohsa-hou-program-for-maladaptive-behaviors-and-internalizing-problems
#4
Haruo Fujino
Psychological and psychiatric dysfunction is a major problem in a substantial proportion of young adults with Down syndrome. Some patients develop psychiatric issues, such as depressive, obsessive-compulsive, or psychotic-like disorders, in their late adolescence or young adulthood. Furthermore, these individuals may experience moderate to severe emotional and psychological distress. Development of a psychosocial treatment to address these issues is needed in addition to psychotropic medication. The current study reports two cases of young adults with Down syndrome, who presented psychiatric symptoms and marked disruption in their daily lives...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28919871/investigating-the-neural-correlates-of-emotion-cognition-interaction-using-an-affective-stroop-task
#5
Nora M Raschle, Lynn V Fehlbaum, Willeke M Menks, Felix Euler, Philipp Sterzer, Christina Stadler
The human brain has the capacity to integrate various sources of information and continuously adapts our behavior according to situational needs in order to allow a healthy functioning. Emotion-cognition interactions are a key example for such integrative processing. However, the neuronal correlates investigating the effects of emotion on cognition remain to be explored and replication studies are needed. Previous neuroimaging studies have indicated an involvement of emotion and cognition related brain structures including parietal and prefrontal cortices and limbic brain regions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28919126/low-dose-ct-for-the-diagnosis-of-appendicitis-in-adolescents-and-young-adults-locat-a-pragmatic-multicentre-randomised-controlled-non-inferiority-trial
#6
Hyuk Jung Kim, Byeong Geon Jeon, Chong Kun Hong, Kye Won Kwon, Seung Bong Han, Soya Paik, Suk Ki Jang, Young Rock Ha, Young Sik Kim, Min Hee Lee, Boem Ha Yi, Eung Jin Shin, Hae Kyung Lee, Hee Kyung Kim, Ho Jung Kim, Jae Hyung Choi, Young Soon Cho, Min-Jeong Kim, Dong Kyu Kim, Ji-Young Choe, Kyueng-Whan Min, Man Sup Lim, Sang Ook Ha, Sang Woo Lim, Youdong Sohn, Young Hwan Lee, Ji Hoon Park, Bon Seung Gu, Hye Seung Lee, Jae Hyuk Lee, Ji Ye Sim, Joonghee Kim, Kyoung Ho Lee, Kyuseok Kim, Soyeon Ahn, Sung-Bum Kang, Yoon Jin Lee, You Hwan Jo, Young Hoon Kim, Yousun Ko, Seung Joon Choi, Bohyung Song, Byung Ho Goh, Chaesuk Lim, Chang Rae Kim, Cho Rong Seo, Eunbaeck Kim, Gio Han, Jae-Hyug Woo, Jinhyun Kim, Kyoungjin Min, Min-A Lee, Min Ju Jeong, Min Kyoung Lee, Yong Su Lim, Young Sup Shim, Sung Bin Park, Chan Woong Kim, Dong Hoon Lee, Seung Eun Lee, Sung Eun Kim, Yoo Shin Choi, Sung Eun Rha, Eun Sun Jung, Gun Hyung Na, Han Joon Kim, Han Mo Yoo, Hye Kyung Chang, Joon Il Choi, Kyu Nam Park, Michael Yong Park, Moon Hyung Choi, Sang Hoon Oh, Seung Eun Jung, Sohee Lee, Soo Ah Im, Soo Hyun Kim, Soon Nam Oh, Tae Ho Hong, Won-Kyung Kang, Young Joon Lee, Young Hwan Lee, Dong Baek Kang, Hyun Soo Han, Jeong Woo Choi, Ki-Jung Yoon, Yong Hwang, Seong Sook Hong, Eui Sung Hwang, Heajin Chung, Hye Young Jang, Jiyoung Hwang, Jun Bum Park, Kyung Yul Hur, Yoon Mi Jeen, Young Joo Lee, Young Shin Cho, Han Jin Cho, Inyoung Choi, Jong Hak Park, Jooyeong Kim, Suk Keu Yeom, Sung Woo Moon, Young Sik Kim, Mi Sung Kim, Dong Hyuk Shin, Heon-Ju Kwon, Pil Cho Choi, Sang Kuk Han, Ji Young Woo, Gu Hyun Kang, Han Myun Kim, Hyun Young Choi, Ik Yang, Jae Ho Jang, Jeong Won Kim, Sang Nam Yoon, Won Hee Kim, Yong Soo Jang, Mi-Suk Park, In Cheol Park, Jae Gil Lee, Min Joung Kim, Yong Eun Chung, Jongmee Lee, Baek-Hui Kim, Chang Hee Lee, Jung-Youn Kim, Sanghee Kang, Sung-Hyuk Choi, Yang Shin Park, Seong Whi Cho, Chan Woo Park, Gi Bong Chae, Taek Guen Ohk, Yong-Hwan Jeon, Nurhee Hong, Dae Han Wi, Jun Hee Lee, Jung Nam Kwon, Seok Youn Lee, Weon-Cheol Han, Young Cheol Song, Mi Jeong Kim, Jung Hyeok Kwon, Seoung Kyu Beak, Sung Jin Kim, Woo Ik Choi, Yu Na Kang, Cheong-Il Shin, Dong Ho Lee, Gyeong Hoon Kang, Ijin Joo, Jeong Hee Yoon, Ji Won Park, Kyu Joo Park, Sang Do Shin, Seung-Bum Ryoo, Seung-Yong Jeong, Su Joa Ahn, Tae Han Kim, Won Chang, Yoon-Hye Kwon, Sang Soo Shin, Hee Joon Kim, Ho Goon Kim, Yong Soo Cho, Yoo Duk Choi, Bong Soo Kim, Chang Lim Hyun, Guk Myung Choi, In Ho Jeong, Kyeong Won Kang, Seung Hyoung Kim, Woo Jeong Kim, Young Joon Kang, Kwang Pyo Kim
BACKGROUND: CT radiation is arguably carcinogenic. Results from single-centre studies, mostly retrospective, have advocated lowering the CT radiation dose for the diagnosis of appendicitis. However, adoption of low-dose CT has been slow. We aimed to assess the effectiveness of low-dose CT compared with standard-dose CT in the diagnosis of appendicitis in adolescents and young adults. METHODS: We did this pragmatic, multicentre, randomised controlled non-inferiority trial at 20 South Korean teaching hospitals with little experience with low-dose CT...
September 11, 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28917270/cancer-related-fatigue-in-adolescents-and-young-adults-a-systematic-review-of-the-literature
#7
REVIEW
E Nowe, Y Stöbel-Richter, A Sender, K Leuteritz, M Friedrich, K Geue
Adolescents and young adults with cancer (AYA) represent a specific age cohort dealing with the disease in a stage of life characterized by development, upheavals, and establishment. The aim of this study was to point out the state of research on how AYA are affected by cancer-related fatigue (CRF). RESULTS: Twelve articles were included. CRF was found to be higher in AYA than in either of the comparison groups, healthy peers and older cancer patients. Most included studies did not measure CRF with multidimensional, fatigue-specific instruments...
October 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28915993/marching-to-a-different-drummer-a-cross-cultural-comparison-of-young-adolescents-who-challenge-gender-norms
#8
Chunyan Yu, Xiayun Zuo, Robert W Blum, Deborah L Tolman, Anna Kågesten, Kristin Mmari, Sara De Meyer, Kristien Michielsen, Sharmistha Basu, Rajib Acharya, Qiguo Lian, Chaohua Lou
PURPOSE: Little is known about how gender norms regulate adolescents' lives across different cultural settings. This study aims to illustrate what is considered as violating gender norms for boys and girls in four urban poor sites as well as the consequences that follow the challenging of gender norms. METHODS: Data were collected as part of the Global Early Adolescent Study, a 15-country collaboration to explore gender norms and health in early adolescence. The current study analyzed narrative and in-depth interviews conducted in urban poor sites in two middle-income (Shanghai, China; and New Delhi, India) and two high-income countries (Baltimore, U...
October 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28915987/interpreting-narratives-within-a-cross-national-interdisciplinary-study-a-case-study-of-a-collaborative-process
#9
Deborah L Tolman, Chunyan Yu, Kristin Mmari
PURPOSE: This article presents a case study of a collaborative process for the analysis of a young girl's narrative on becoming an adolescent in Shanghai. The purpose was to illuminate how interpretation of narratives can be strengthened with a diverse team of researchers. METHODS: Three different researchers, each representing a different discipline and lens for analyzing qualitative data, collaboratively analyzed and interpreted a 12-year-old girl's narrative from Shanghai as part of the Global Early Adolescent Study...
October 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28915986/exploration-of-gender-norms-and-socialization-among-early-adolescents-the-use-of-qualitative-methods-for-the-global-early-adolescent-study
#10
REVIEW
Kristin Mmari, Robert W Blum, Rebkha Atnafou, Elisa Chilet, Sara de Meyer, Omaima El-Gibaly, Sharmista Basu, Bamidele Bello, Beatrice Maina, Xiayun Zuo
PURPOSE: The Global Early Adolescent Study (GEAS) was launched in 2014 with the primary goal of understanding the factors in early adolescence that predispose young people to subsequent sexual risks, and conversely, those that promote healthy sexuality across different cultural contexts. The present article describes the methodology that was used for the first phase of GEAS, which consisted of conducting qualitative research to understand the gendered transitions into adolescence and the role that gender norms play within the key relationships of adolescents...
October 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28915582/microrna-610-suppresses-osteosarcoma-oncogenicity-via-targeting-twist1-expression
#11
Chi Jin, Yongjian Feng, Yongjian Ni, Zhonglin Shan
Osteosarcoma is the most frequent primary bone tumor affects adolescents and young adults. Recently, microRNAs (miRNAs) are short, non-coding and endogenous RNAs that played as important roles in the initiation and progression of tumors. In this study, we try to explore the biological function and expression of miR-610 in the osteosarcoma. We showed that miR-610 expression was downregulated in the osteosarcoma tissues and cell lines. Elevated expression of miR-610 suppressed the osteosarcoma cell proliferation, cell cycle, invasion and EMT program...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28914364/unhealthy-lifestyle-habits-and-diabetes-specific-health-related-quality-of-life-in-youths-with-type-1-diabetes
#12
Enza Mozzillo, Eugenio Zito, Claudio Maffeis, Elena De Nitto, Giulio Maltoni, Marco Marigliano, Stefano Zucchini, Adriana Franzese, Giuliana Valerio
AIMS: Management of type 1 diabetes mellitus (T1DM) influences several aspects of life, such as adherence to healthy lifestyle habits and health-related quality of life (HRQoL). Our aim was to evaluate the association between unhealthy lifestyle habits and HRQoL in adolescents and young adults with T1DM. METHODS: Two hundred and forty-two Caucasian patients (13-19 years) consecutively enrolled over a 12-month period in three Regional Pediatric Diabetes Centers in Italy...
September 15, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28914116/defining-a-core-outcome-set-for-adolescent-and-young-adult-patients-with-a-spinal-deformity
#13
Marinus de Kleuver, Sayf S A Faraj, Roderick M Holewijn, Niccole M Germscheid, Raphael D Adobor, Mikkel Andersen, Hans Tropp, Benny Dahl, Heli Keskinen, Anders Olai, David W Polly, Miranda L van Hooff, Tsjitske M Haanstra
Background and purpose - Routine outcome measurement has been shown to improve performance in several fields of healthcare. National spine surgery registries have been initiated in 5 Nordic countries. However, there is no agreement on which outcomes are essential to measure for adolescent and young adult patients with a spinal deformity. The aim of this study was to develop a core outcome set (COS) that will facilitate benchmarking within and between the 5 countries of the Nordic Spinal Deformity Society (NSDS) and other registries worldwide...
September 15, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28913981/age-dependent-expression-of-nav1-9-channels-in-medial-prefrontal-cortex-mpfc-pyramidal-neurons-in-rats
#14
Maciej Gawlak, Bartłomiej Szulczyk, Adam Berlowski, Katarzyna Grzelka, Anna Stachurska, Justyna Pelka, Katarzyna Czarzasta, Maciej Malecki, Przemyslaw Kurowski, Ewa Nurowska, Pawel Szulczyk
Developmental changes that occur in the prefrontal cortex during adolescence alter behavior. These behavioral alterations likely stem from changes in prefrontal cortex neuronal activity, which may depend on the properties and expression of ion channels. Nav1.9 sodium channels conduct a Na(+) current that is TTX resistant with a low threshold and noninactivating over time. The purpose of this study was to assess the presence of Nav1.9 channels in medial prefrontal cortex (mPFC) layer II and V pyramidal neurons in young (20-day-old), late adolescent (60-day-old) and adult (6-7-month-old) rats...
September 15, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/28913329/structured-transition-protocol-for-children-with-cystinosis
#15
Rupesh Raina, Joseph Wang, Vinod Krishnappa
The transition from pediatric to adult medical services has a greater impact on the care of adolescents or young adults with chronic diseases such as cystinosis. This transition period is a time of psychosocial development and new responsibilities placing these patients at increased risk of non-adherence. This can lead to serious adverse effects such as graft loss and progression of the disease. Our transition protocol will provide patients, families, physicians, and all those involved a structured guide to transitioning cystinosis patients...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28912181/hypertrophic-cardiomyopathy-genetics-pathogenesis-clinical-manifestations-diagnosis-and-therapy
#16
REVIEW
Ali J Marian, Eugene Braunwald
Hypertrophic cardiomyopathy (HCM) is a genetic disorder that is characterized by left ventricular hypertrophy unexplained by secondary causes and a nondilated left ventricle with preserved or increased ejection fraction. It is commonly asymmetrical with the most severe hypertrophy involving the basal interventricular septum. Left ventricular outflow tract obstruction is present at rest in about one third of the patients and can be provoked in another third. The histological features of HCM include myocyte hypertrophy and disarray, as well as interstitial fibrosis...
September 15, 2017: Circulation Research
https://www.readbyqxmd.com/read/28910871/-mucosa-associated-lymphoid-tissue-lymphoma-in-children-and-adolescents-a-clinicopathologic-study-of-5-cases
#17
J Hu, J L Xie, Z J Zhou, X G Zhou
Objective: To investigate the pathological features and clinical manifestations of mucosa-associated lymphoid tissue (MALT) lymphoma in children and adolescents. Methods: Five cases of MALT lymphoma in children were investigated by morphology and immunophenotyping along with clinical follow-up. Results: Five cases of MALT lymphoma occurred in the antrum, orbit, parotid gland and nasopharynx. All patients had no B symptoms and only one patient showed a local mass with ulcer. One case presented with cervical lymph node enlargement, and 4 cases showed no evidence of lymphadenopathy...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28910258/recommendations-will-the-tobacco-and-vaping-products-act-go-far-enough
#18
Kurt L Tulsieram, Sylvia Rinaldi, Jacob J Shelley
E-cigarette use among adolescents and young adults in Canada is increasing. Potvin's (2016) editorial outlined the need for more evidence on e-cigarettes as a gateway to combustible cigarettes and their toxicity. Since then, new evidence has emerged supporting the gateway effect and establishing toxicity. Health Canada has reviewed the evidence and recently opted to regulate e-cigarettes, including prohibiting brick-and-mortar retail access for youth under 18 years of age. However, many online e-cigarette retailers exist, which increases adolescents' access to e-cigarettes and currently unregulated nicotine-containing refills...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28910174/family-and-peer-group-substance-abuse-as-a-risk-factor-for-opioid-misuse-behaviors-for-a-young-adult-with-cancer-related-pain-a-case-study
#19
Kelly R Peck, Jennifer L Harman, Doralina L Anghelescu
The purpose of this report is to illustrate the importance of assessing for family, peer, and personal substance abuse risk factors in the case of a young adult with cancer-related pain and behaviors potentially indicative of opioid misuse (OM). A thorough clinical interview and an OM screening measure revealed important information about the patient's family and social environment. Based on this information, the treatment team acted quickly to prevent additional aberrant opioid-associated behaviors (AOBs)...
September 14, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28905489/consensus-and-controversies-regarding-the-treatment-of-rhabdomyosarcoma
#20
REVIEW
Scott C Borinstein, Diana Steppan, Masanori Hayashi, David M Loeb, Michael S Isakoff, Odion Binitie, Andrew S Brohl, Julia A Bridge, Mark Stavas, Eric T Shinohara, William H Meyer, Damon R Reed, Lars M Wagner
Optimal treatment of rhabdomyosarcoma (RMS) requires multidisciplinary approach, incorporating chemotherapy with local control. Although current therapies are built on cooperative group trials, a comprehensive standard of care to guide clinical decision making has been lacking, especially for relapsed patients. Therefore, we assembled a panel of pediatric and adolescent and young adult sarcoma experts to develop treatment guidelines for managing RMS and to identify areas in which further research is needed...
September 14, 2017: Pediatric Blood & Cancer
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