Claudia Hülpüsch, Avidan Uriel Neumann, Matthias Reiger, Julius Clemens Fischer, Amedeo de Tomassi, Gertrud Hammel, Carina Gülzow, Megan Fleming, Hendrik Dapper, Michael Mayinger, Marco Vogel, Christina Ertl, Stephanie Elisabeth Combs, Claudia Traidl-Hoffmann, Kai Joachim Borm
IMPORTANCE: The interindividual differences in severity of acute radiation dermatitis are not well understood. To date, the pathomechanism and interplay of microbiome and radiodermatitis before and during treatment remain largely unknown. OBJECTIVE: To assess the association of skin microbiome baseline composition and dynamics with severity of radiodermatitis in patients undergoing adjuvant radiotherapy for breast cancer. DESIGN, SETTING, AND PARTICIPANTS: A longitudinal prospective pilot observational study was conducted between January 2017 and January 2019...
February 1, 2024: JAMA Oncology