Giuseppina Gallucci, Fabio Maria Turazza, Alessandro Inno, Maria Laura Canale, Nicola Silvestris, Roberto Farì, Alessandro Navazio, Carmine Pinto, Luigi Tarantini
Atherosclerosis, a complex metabolic-immune disease characterized by chronic inflammation driven by the buildup of lipid-rich plaques within arterial walls, has emerged as a pivotal factor in the intricate interplay between cancer and cardiovascular disease. This bidirectional relationship, marked by shared risk factors and pathophysiological mechanisms, underscores the need for a comprehensive understanding of how these two formidable health challenges intersect and influence each other. Cancer and its treatments can contribute to the progression of atherosclerosis, while atherosclerosis, with its inflammatory microenvironment, can exert profound effects on cancer development and outcomes...
April 11, 2024: International Journal of Molecular Sciences