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https://www.readbyqxmd.com/read/29786162/hospitals-and-the-generic-versus-brand-name-prescription-decision-in-the-outpatient-sector
#1
Gerald J Pruckner, Thomas Schober
Health care payers try to reduce costs by promoting the use of cheaper generic drugs. We show strong interrelations in drug prescriptions between the inpatient and outpatient sectors by using a large administrative dataset from Austria. Patients with prior hospital visits have a significantly lower probability of receiving a generic drug in the outpatient sector. The size of the effect depends on both the patient and doctor characteristics, which could be related to the differences in hospital treatment and heterogeneity in the physicians' adherence to hospital choices...
May 22, 2018: Health Economics
https://www.readbyqxmd.com/read/29786127/crystal-ball-or-magic8-ball-reply-hazy-try-again
#2
EDITORIAL
A James O'Malley, Sandra L Wong
No abstract text is available yet for this article.
May 21, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29785539/the-effect-of-spironolactone-on-the-incidence-of-contrast-induced-nephropathy-in-patients-undergoing-cardiac-catheterization-study-design-and-rationale
#3
Alhasan Mujtaba, Mohammed A Taher, Mazin A Hazza, Hassan M Al-Rubaye, Asaad H Kata, Hamid AbdulWahab, AbdulAmeer AbdulBari, Hayder K AlRubay
INTRODUCTION: Patients undergoing coronary catheterization are at high risk of developing contrast-induced nephropathy (CIN) acute kidney injury (AKI). Several approaches have been supposed to limit such an effect but with mixed results or non-practical methods. Spironolactone is supposed to be effective as a nephroprotective agent in animal studies. This study will try to measure the effect of spironolactone on the incidence of CIN-AKI in patients undergoing coronary catheterization (angiography angioplasty)...
May 21, 2018: Cardiology and Therapy
https://www.readbyqxmd.com/read/29785224/pseudarthrosis-of-the-calcaneus-advantages-of-regenerative-medicine-in-the-management-of-a-rare-entity-a-case-report-and-review-of-literature
#4
Bouaziz Wajdi, Mohamed Ali Rebai, Walid Baya, Nabil Krid, Wassim Zribi, Hassib Keskes
Background: The follow-up of calcaneal fractures has shown that they are difficult to manage and lead to multiple complications such as malunion and subtalar osteoarthritis. Pseudarthrosis of the calcaneus is an extremely rare complication, which was described in the literature through case reports.In the existing literature, only seven studies, including thirteen patients have reported the nonunion. However, to the best of our knowledge, no study elucidates the role of new techniques of regenerative medicine such as Bone Marrow Concentrates (BMC) or Platelet Rich Plasma (PRP) in the management...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29785195/combined-therapies-of-modified-taiyi-miraculous-moxa-roll-and-cupping-for-patients-with-lumbar-intervertebral-disc-herniation
#5
Chunyue Cai, Yuefeng Gong, Dayong Dong, Jinbiao Xue, Xiaoting Zheng, Zhangfeng Zhong, Jialong Shao, Daguo Mi
Lumbar intervertebral disc herniation is a kind of syndrome caused by stimulation or pressure of nerve root and cauda equina due to intervertebral disc disorder, fibrous ring rupture, and pulpiform nucleus protrusion. Application of traditional Chinese medicine (TCM) including acupuncture therapy and cupping therapy is unique and effective treatment for lumbar intervertebral disc herniation in China. Hence, we try to investigate the combined clinical efficacy of modified Taiyi miraculous moxa roll and cupping therapy on patients with lumbar intervertebral disc herniation...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29783764/intensity-of-multilingual-language-use-predicts-cognitive-performance-in-some-multilingual-older-adults
#6
Anna Pot, Merel Keijzer, Kees de Bot
Cognitive advantages for bilinguals have inconsistently been observed in different populations, with different operationalisations of bilingualism, cognitive performance, and the process by which language control transfers to cognitive control. This calls for studies investigating which aspects of multilingualism drive a cognitive advantage, in which populations and under which conditions. This study reports on two cognitive tasks coupled with an extensive background questionnaire on health, wellbeing, personality, language knowledge and language use, administered to 387 older adults in the northern Netherlands, a small but highly multilingual area...
May 19, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29782796/resolution-measurement-from-a-single-reconstructed-cryo-em-density-map-with-multi-scale-spectral-analysis
#7
Yu-Jiao Yang, Shuai Wang, Biao Zhang, Hong-Bin Shen
As a relatively new technology to solve the 3D structure of a protein or protein complex, the Single-Particle Reconstruction (SPR) of cryo-EM images shows much superiority and is in a rapidly developing stage. Resolution measurement in SPR, which evaluates the quality of a reconstructed 3D density map, plays a critical role for promoting methodology development of SPR and structural biology. Due to there is no benchmark map in a new structure generation, how to realize the resolution estimation of a new map is still an open problem...
May 21, 2018: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29782228/participation-retention-and-utilization-of-a-web-based-chronic-disease-self-management-intervention-among-older-adults
#8
Jennifer Dickman Portz, Walter F LaMendola
BACKGROUND: Web-based self-management (web-based SM) interventions provide a potential resource for older adults to engage in their own chronic disease management. The purpose of this study is to investigate the effect of age on participation, retention, and utilization of a web-based SM intervention. MATERIALS AND METHODS: This study reports the results of a secondary data analysis of the effects of age in a randomized trial of a web-based diabetes SM intervention...
May 21, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29782184/the-growth-of-preantral-follicles-and-the-impact-of-different-supplementations-and-circumstances-a-review-study-with-focus-on-bovine-and-human-preantral-follicles
#9
Zahra Rajabi, Zunair Khokhar, Hossein Yazdekhasti
One of the most important concerns cancer survivors face is fertility. Current treatment modalities often result in damage to the reproductive system. Different options have been proposed to preserve the fertility of affected women, and many attempts have been made to improve their chance of childbearing after therapy. Cryopreservation of ovarian tissue and follicles before the onset of cancer treatment and then either transplantation of ovarian tissue or culture of ovarian tissue and individual follicles in vitro is a commonly cited approach...
May 21, 2018: Cellular Reprogramming
https://www.readbyqxmd.com/read/29780835/risk-factors-for-anterior-cruciate-ligament-injury-in-competitive-adolescent-alpine-skiers
#10
Maria Westin, Marita L Harringe, Björn Engström, Marie Alricsson, Suzanne Werner
Background: There is a high risk for anterior cruciate ligament (ACL) injuries in alpine skiers. To reduce or try to prevent these injuries, intrinsic and extrinsic risk factors need to be identified. Purpose: To identify possible intrinsic and extrinsic ACL injury risk factors among competitive adolescent alpine skiers. Study Design: Case-control study; Level of evidence, 3. Methods: Between 2006 and 2009, a cohort of 339 alpine ski students (176 male, 163 female) from Swedish ski high schools were prospectively observed in terms of ACL injuries...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29780698/multiculturalism-and-interculturalism-redefining-nationhood-and-solidarity
#11
Riva Kastoryano
Theoretical and normative approaches regarding the question of diversity and integration, such as multiucluturalims and interculturalims compete in an attempt to redefine citizenship and nationhood. Most analyses have been single-theory-oriented, leading to multiple, contested and controversial interpretations of integration and democratic public spaces. Transnationalism raises the question of the limits of national public space and extends the concept of cultural integration beyond borders challenging the normative theories of multiculturalism and interculturalism bounded to national societies...
2018: Comparative Migration Studies
https://www.readbyqxmd.com/read/29780430/healthcare-professionals-perceptions-on-the-emotional-impact-of-having-an-inadequate-response-to-antidepressant-medications-survey-and-prospective-patient-audit
#12
Rajnish Mago, Andrea Fagiolini, Emmanuelle Weiller, Catherine Weiss
Background: Despite the availability of effective antidepressants, about half of patients with major depressive disorder (MDD) display an inadequate response to their initial treatment. A large patient survey recently reported that 29.8% of MDD patients experiencing an inadequate treatment response felt frustrated about their medication and 19.2% were frustrated with their healthcare provider. This survey and chart audit evaluated healthcare professionals' (HCP) views on the emotional impact of having an inadequate response to antidepressant medication...
2018: Annals of General Psychiatry
https://www.readbyqxmd.com/read/29780297/impact-of-osteoarthritis-on-household-catastrophic-health-expenditures-in-korea
#13
Hyoungyoung Kim, Soo-Kyung Cho, Daehyun Kim, Dalho Kim, Sun-Young Jung, Eun Jin Jang, Yoon-Kyoung Sung
Background: Osteoarthritis (OA) is a disease of old age whose prevalence is increasing. This study explored the impact of OA on household catastrophic health expenditure (CHE) in Korea. Methods: We used data on 5,200 households from the Korea Health Panel Survey in 2013 and estimated annual living expenses and out-of-pocket (OOP) payments. Household CHE was defined when a household's total OOP health payments exceeded 10%, 20%, 30%, or 40% of the household's capacity to pay...
May 21, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29780247/impact-of-nanoparticles-on-neuron-biology-current-research-trends
#14
REVIEW
Firdos Alam Khan, Dana Almohazey, Munthar Alomari, Sarah Ameen Almofty
Nanoparticles have enormous applications in textiles, cosmetics, electronics, and pharmaceuticals. But due to their exceptional physical and chemical properties, particularly antimicrobial, anticancer, antibacterial, anti-inflammatory properties, nanoparticles have many potential applications in diagnosis as well as in the treatment of various diseases. Over the past few years, nanoparticles have been extensively used to investigate their response on the neuronal cells. These nanoparticles cause stem cells to differentiate into neuronal cells and promote neuronal cell survivability and neuronal cell growth and expansion...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29780203/only-when-the-societal-impact-potential-is-high-a-panel-study-of-the-relationship-between-public-service-motivation-and-perceived-performance
#15
Nina van Loon, Anne Mette Kjeldsen, Lotte Bøgh Andersen, Wouter Vandenabeele, Peter Leisink
Many studies find positive associations between public service motivation (PSM) and performance, but much of this literature is based on cross-sectional data prone to endogeneity and common method bias. Moreover, we know little about potential moderators. In this study, we test the moderating role of societal impact potential (SIP)-the degree to which the job is perceived to provide opportunities to contribute to society. We use cross-sectional data from 13,967 employees in 2010 and 2012 aggregated to construct longitudinal data for 42 organizations...
June 2018: Review of Public Personnel Administration
https://www.readbyqxmd.com/read/29779652/the-enzymology-of-prochlorosin-biosynthesis
#16
Silvia C Bobeica, Wilfred A van der Donk
Lanthipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links formed through addition of a cysteine to a dehydroalanine (to form lanthionine) or to a dehydrobutyrine (to form 3-methyllanthionine). Genome sequencing of marine cyanobacteria lead to the discovery of 1.6 million open reading frames encoding lanthipeptides. In many cases, a genome encodes a single lanthipeptide synthetase, but a large number of substrates. The enzymatic modification process in Prochlorococcus MIT9313 has been reconstituted in vitro, and a variety of experimental approaches have been used to try and understand how one enzyme is capable of modifying 30 different substrates...
2018: Methods in Enzymology
https://www.readbyqxmd.com/read/29779391/-is-preoperative-systemic-chemotherapy-recommended-for-resectable-colorectal-liver-metastases-oncosurgical-aspects
#17
Kristóf Dede, Zsuzsa Póti, Attila Bursics
Surgical resection is still the only curative treatment for colorectal liver metastases, but this is one part of a complex therapy. Nowadays a patient with colorectal liver metastasis is not treated only by a surgeon or by an oncologist or even only by an invasive radiologist. Collective decisions, complement treatments give the only chance to treat these patients for longer time. Patients with colorectal liver metastases could be regarded as patients with chronic disease. Specially interesting are the various treatment options of resectable colorectal liver metastases...
May 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29777800/cardiotoxicity-associated-with-radiotherapy-in-breast-cancer-a-question-based-review-with-current-literatures
#18
REVIEW
Qian Zhu, Youlia M Kirova, Lu Cao, Alexandre Arsene-Henry, Jiayi Chen
Radiotherapy is an indispensable unit of multidisciplinary treatment of breast cancer. Although the application of modern techniques has led to a significantly reduction in radiation-induced heart disease, it is still recognized as the leading causes of morbidity and mortality among breast cancer survivors. With the growing number of long-term survivors, it is important to understand the cardiovascular risks associated with radiotherapy. Questions exist regarding the existence or not of a safe radiation threshold dose that the heart (or its substructures) can receive and strategies to minimize risk of radiation...
May 2, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29777368/organizational-context-and-individual-adaptability-in-promoting-perceived-importance-and-use-of-best-practices-for-substance-use
#19
Danica K Knight, George W Joe, David T Morse, Corey Smith, Hannah Knudsen, Ingrid Johnson, Gail A Wasserman, Nancy Arrigona, Larkin S McReynolds, Jennifer E Becan, Carl Leukefeld, Tisha R A Wiley
This study examines associations among organizational context, staff attributes, perceived importance, and use of best practices among staff in community-based, juvenile justice (JJ) agencies. As part of the National Institute on Drug Abuse's Juvenile Justice-Translational Research on Interventions for Adolescents in the Legal System (JJ-TRIALS) study, 492 staff from 36 JJ agencies were surveyed about the perceived importance and use of best practices within their organization in five substance use practice domains: screening, assessment, standard referral, active referral, and treatment support...
May 18, 2018: Journal of Behavioral Health Services & Research
https://www.readbyqxmd.com/read/29776369/prevention-and-treatment-of-malaria-in-pregnancy-what-do-pregnant-women-and-health-care-workers-in-east-india-know-and-do-about-it
#20
Lora Sabin, Evan M S Hecht, Mohamad I Brooks, Mrigendra P Singh, Kojo Yeboah-Antwi, Abanish Rizal, Blair J Wylie, Philip A Bondzie, Matthew Banos, Jordan Tuchman, Neeru Singh, Davidson H Hamer
BACKGROUND: Limited qualitative research has been performed in India to investigate views and behaviours of pregnant women regarding malaria despite the threat of malaria-related adverse maternal and neonatal outcomes. To address this gap, a comprehensive study on malaria prevention and treatment attitudes, knowledge and behaviour among pregnant women in India was conducted. METHODS: Pregnant women and healthcare workers (HCWs), encompassing clinic-based providers, traditional birth attendants, and auxiliary nurse-midwives were enrolled for in-depth interviews (IDIs) at 7 hospital sites and nearby communities in Jharkhand and Chhattisgarh States...
May 18, 2018: Malaria Journal
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