keyword
https://read.qxmd.com/read/38487110/trigeminal-neuralgia-secondary-to-herpes-simplex-virus-type-1-infection-treated-with-oral-acyclovir
#1
Amal J Alfaifi, Ohood S Wasli, Thamer M Almalki, Ahmad Y Alqassim
Trigeminal neuralgia (TN) is characterized by episodic electric, shock-like facial pain. Though often idiopathic, herpes simplex virus type 1 (HSV-1) reactivation can rarely cause symptomatic TN. We report the case of a 30-year-old woman who developed oral HSV-1 lesions followed by right-sided TN pain. MRI of the brain did not reveal neurovascular compression. TN pain completely resolved with oral acyclovir treatment alone, without anticonvulsants. This highlights the importance of considering atypical etiologies such as HSV-1 reactivation in TN evaluation...
February 2024: Curēus
https://read.qxmd.com/read/38270619/in-situ-tissue-profile-of-rat-trigeminal-nerve-in-trigeminal-neuralgia-using-spatial-transcriptome-sequencing
#2
JOURNAL ARTICLE
Wenbin Wei, Yuemin Liu, Yifen Shen, Tao Yang, Yabing Dong, Zixiang Han, Yiwen Wang, Zhiyang Liu, Ying Chai, Mengjie Zhang, Hanshao Wang, Hao Shen, Yihang Shen, Minjie Chen
BACKGROUND: Trigeminal neuralgia (TN) is the most common neuropathic disorder in the maxillofacial region. The etiology and pathogenesis of TN have not been clearly determined to date, although there are many hypotheses. OBJECTIVE: The goal of this study was to investigate the interactions between different types of cells in TN, particularly the impact and intrinsic mechanism of demyelination on the trigeminal ganglion, and to identify new important target genes and regulatory pathways in TN...
January 25, 2024: International Journal of Surgery
https://read.qxmd.com/read/38246665/-developmental-history-of-microvascular-decompression-surgery-for-cranial-nerve-dysfunction
#3
JOURNAL ARTICLE
Akinori Kondo
Trigeminal neuralgia is characterized by severe lancinating pain in the face and hemifacial spasms displayed by continuous facial muscle twitching, which may impair a patient's quality of life. Before 1960, in the United States of America, the treatment of such symptoms was only partial rhizotomy of the cranial nerves, which resulted in postoperative complications.1, 2) Afterwards, in the late 1960s, it became evident that the etiology of symptoms was an elicited arterial compression of the cranial nerves at the "Root Entry/Exit zone...
January 2024: No Shinkei Geka. Neurological Surgery
https://read.qxmd.com/read/38154423/independent-association-of-the-meckel-s-cave-with-trigeminal-neuralgia-and-development-of-a-screening-tool
#4
JOURNAL ARTICLE
Fang Zhang, Yang Ni, Guoxuan Luo, Yong Zhang, Jinzhi Lin
PURPOSE: To 1) investigate the association of the properties of the Meckel's cave (MC) with TN occurrence (i.e., affected vs. unaffected nerves) and whether such association was independent of neurovascular contact (NVC); and 2) develop an objective screening tool for TN. MATERIALS AND METHODS: Two hundred and nineteen trigeminal nerves were included. (The severity of) NVC was identified for individual nerve, and a set of 107 radiomic features were extracted to characterize various properties of each MC...
December 16, 2023: European Journal of Radiology
https://read.qxmd.com/read/38148702/-dolichoectasia-of-the-basilar-artery-caused-by-cystic-medial-degeneration-as-a-cause-of-neurovascular-conflict-with-damage-to-the-trigeminal-facial-and-vestibulocochlear-nerves
#5
JOURNAL ARTICLE
T N Charnukha, I P Maryenko, S A Likhachev, H V Kleban, S A Mironov
Cystic medial degeneration (Gsell-Erdheim syndrome, cystic medial necrosis) is considered to be a nonspecific histological manifestation of a group of diseases characterized by degenerative changes in the media, affecting primarily the aorta and adjacent branches, which leads to destruction of the vessel wall, followed by its expansion and, possibly, rupture. The authors describe a case of a 65-year-old female patient with a neurovascular conflict of the three cranial nerves with dolichoectatic basilar artery due to cystic medial degeneration...
2023: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38130833/trigeminal-neuralgia-associated-with-dural-arteriovenous-fistula-a-case-report-and-literature-reviews
#6
Hao Zhou, Xingrong Wei, Defeng Zeng, Shuguang Zhang, Xueqian Hu, Zhenqin Wei, Yang Li
Trigeminal neuralgia is a paroxysmal, intense electric shock-like, or knife-like, recurrent pain that affects one or more sense areas of the unilateral facial trigeminal nerve. It can be classified into two groups from an etiological standpoint: primary and secondary. The pain episodes brought on by such vascular compression are still categorized as primary trigeminal neuralgia, despite the fact that microvascular compression of the trigeminal nerve root has now been demonstrated to be the primary cause. A rare and complicated condition known as a dural arteriovenous fistula (DAVF) can irritate the Gasserian ganglion or compress the trigeminal nerve's root entry zone (REZ), leading to secondary trigeminal neuralgia (TN)...
2023: Frontiers in Neurology
https://read.qxmd.com/read/38062385/trigeminal-neuralgia-caused-by-a-persistent-primitive-trigeminal-artery-variant-passing-through-meckel-s-cavity-a-case-report
#7
JOURNAL ARTICLE
Zhengyan Zhu, Zhenpan Zhang, Risheng Liang
BACKGROUND: Persistent primitive trigeminal artery variant (PPTAv) is a rare remnant of the primitive intracranial embryonic anastomotic arteries, and its persistence has an unknown etiology. Trigeminal neuralgia attributed to a PPTAv passing through Meckel's cavity is extremely uncommon. CASE PRESENTATION: A 73-year-old woman presented with right-sided facial pain for 10 years that had failed to respond to medication. Magnetic resonance angiography suggested the presence of a PPTAv compressing the trigeminal nerve, as the abnormal artery originated from the right internal carotid artery...
December 7, 2023: BMC Neurology
https://read.qxmd.com/read/38048567/trigeminal-neuralgia-secondary-to-osteoma-and-vascular-compression-illustrative-case
#8
JOURNAL ARTICLE
Chenglong Cao, Mingwu Li, Min Wu, Xiaofeng Jiang
BACKGROUND: Trigeminal neuralgia (TN) is a common neurosurgical issue that has a detrimental impact on patients' quality of life. Osteoma at the petrous apex is a rare etiology of TN. Here, the authors present a case involving the co-occurrence of petrous osteoma and a vascular loop around the trigeminal nerve. Both exerted pressure or compression on the exit of the trigeminal nerve. OBSERVATIONS: A 46-year-old male presented with a 3-year history of persistent severe pain in the right side of his face...
December 4, 2023: J Neurosurg Case Lessons
https://read.qxmd.com/read/38033529/the-role-of-artificial-intelligence-in-the-management-of-trigeminal-neuralgia
#9
REVIEW
Marco Battistelli, Alessandro Izzo, Manuela D'Ercole, Quintino Giorgio D'Alessandris, Nicola Montano
Trigeminal neuralgia (TN) is the most frequent facial pain. It is difficult to treat pharmacologically and a significant amount of patients can become drug-resistant requiring surgical intervention. From an etiologically point of view TN can be distinguished in a classic form, usually due to a neurovascular conflict, a secondary form (for example related to multiple sclerosis or a cerebello-pontine angle tumor) and an idiopathic form in which no anatomical cause is identifiable. Despite numerous efforts to treat TN, many patients experience recurrence after multiple operations...
2023: Frontiers in Surgery
https://read.qxmd.com/read/38020635/association-of-concomitant-continuous-pain-in-trigeminal-neuralgia-with-a-narrow-foramen-ovale
#10
JOURNAL ARTICLE
Shuo Li, Chenlong Liao, Xiaosheng Yang, Wenchuan Zhang
BACKGROUND: The pathogenesis of concomitant continuous pain remains unclear and is worthy of further study. In this clinical study, we aimed to explore the potential role of a narrow foramen ovale in the development of concomitant continuous pain. METHODS: A total of 108 patients with classical trigeminal neuralgia affecting the third branch of the trigeminal nerve and 46 healthy individuals were enrolled in this study. Three-dimensional reconstructed computerized tomography images of all participants were collected, and the morphometric features of the foramen ovale were examined by two investigators who were blinded to the clinical data of the patients...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37996213/microvascular-decompression-for-trigeminal-neuralgia-a-retrospective-analysis-of-long-term-outcomes-and-prognostic-factors
#11
JOURNAL ARTICLE
L Amaya Pascasio, B De La Casa-Fages, E Esteban de Antonio, F Grandas, R García-Leal, F Ruiz Juretschke
INTRODUCTION: Microvascular decompression is considered to be the most effective and only etiological surgical treatment for classical trigeminal neuralgia, relieving the neurovascular compression found in up to 95% of cases. This study aims to report the long-term outcomes and to identify prognostic factors in a series of patients with trigeminal neuralgia treated by microvascular decompression. METHODS: A retrospective observational study of 152 consecutive patients operated by microvascular decompression with at least six months of follow-up...
2023: Neurología
https://read.qxmd.com/read/37942652/recurrent-cryptogenic-strokes-in-a-young-female-as-a-novel-presentation-of-parry-romberg-syndrome-a-case-report-and-review
#12
JOURNAL ARTICLE
Vijaya Lakshmi Valaparla, Milena Lobaina, Chilvana Patel, Xiangping Li, Anand Vilaschandra Patel
INTRODUCTION: Parry Romberg Syndrome (PRS) is a less common genetic condition presenting with progressive hemifacial atrophy involving skin, underlying connective tissue, muscle and facial bone. Neurological manifestations include seizures, headaches, deafness and trigeminal neuralgia refractory to medications, while stroke is a less common presentation. MATERIALS AND METHODS: A 43-year-old right-handed female with previous history of Lower Motor Neuron (LMN) type facial palsy, seizure disorder and linear scleroderma, presented to our clinic with recurrent cryptogenic strokes...
November 9, 2023: International Journal of Neuroscience
https://read.qxmd.com/read/37809543/debilitating-trigeminal-neuralgia-secondary-to-idiopathic-intracranial-hypertension
#13
Assad Ali, Raphael Bastianon Santiago, Julio Isidor, Mauricio Mandel, Mohamad Adada, Michal Obrzut, Badih Adada, Hamid Borghei-Razavi
Idiopathic intracranial hypertension (IIH) is characterized by raised intracranial pressure with unknown etiology. The most common neurological manifestations are headache and visual loss. Often, other cranial nerve impairments are also found, most commonly in the VI nerve. Trigeminal neuralgia (TN) is a debilitating condition that is most frequently caused by neurovascular pathology, but TN secondary to IIH is a rare and poorly described topic. Possible explanations of TN in these patients include the distortion of the local anatomy at CN entry zones and fluid displacement causing distortion of the Meckel's cave...
September 2023: Heliyon
https://read.qxmd.com/read/37643657/trigeminal-neuralgia-as-a-primary-demyelinating-disease-potential-multimodal-evidence-and-remaining-controversies
#14
REVIEW
Seyed H Mousavi, John W Lindsey, Karin N Westlund, Sascha R A Alles
Trigeminal neuralgia is a heterogeneous disorder with likely multifactorial and complex etiology; however, trigeminal nerve demyelination and injury are observed in almost all patients with trigeminal neuralgia. The current management strategies for trigeminal neuralgia primarily involve anticonvulsants and surgical interventions, neither of which directly address demyelination, the pathological hallmark of trigeminal neuralgia, and treatments targeting demyelination are not available. Demyelination of the trigeminal nerve has been historically considered a secondary effect of vascular compression, and as a result, trigeminal neuralgia is not recognized nor treated as a primary demyelinating disorder...
February 2024: Journal of Pain
https://read.qxmd.com/read/37539368/unique-etiology-of-trigeminal-neuralgia-after-acute-ischemic-stroke
#15
James L Walker, Jared McLaughlin, John Dickerson, Sukruta S Pradhan, Felecia A Newton
No abstract text is available yet for this article.
2023: Kansas Journal of Medicine
https://read.qxmd.com/read/37508941/multiple-sclerosis-a-demyelinating-disorder-and-its-dental-considerations-a-literature-review-with-own-case-report
#16
REVIEW
Khalid Al Johani, Mashael Fudah, Mohammad Al-Zahrani, Hassan Abed, Kumar Chandan Srivastava, Deepti Shrivastava, Marco Cicciù, Giuseppe Minervini
Multiple sclerosis (MS) is a chronic, autoimmune condition that primarily affects the myelin sheath covering the neurons of the central nervous system, including those of the brain and spinal cord. Although the etiology is not completely understood, various factors, such as genetic infections and environmental background, play a role in the pathogenesis. Repeated active episodes of MS characterized with marked inflammation results in the scarring of particular nerve segments, and eventually results in functional impairment over a period of time...
June 29, 2023: Brain Sciences
https://read.qxmd.com/read/37480619/progress-in-animal-models-of-trigeminal-neuralgia
#17
REVIEW
Xiaohan Ma, Taomin Zhu, Jin Ke
OBJECTIVE: This review aims to systematically summarize the methods of establishing various models of trigeminal neuralgia (TN), the scope of application, and current animals used in TN research and the corresponding pain measurements, hoping to provide valuable reference for researchers to select appropriate TN animal models and make contributions to the research of pathophysiology and management of the disease. DESIGN: The related literatures of TN were searched through PubMed database using different combinations of the following terms and keywords including but not limited: animal models, trigeminal neuralgia, orofacial neuropathic pain...
July 11, 2023: Archives of Oral Biology
https://read.qxmd.com/read/37436558/sex-differences-in-trigeminal-neuralgia-a-focus-on-radiological-and-clinical-characteristics
#18
JOURNAL ARTICLE
Gianfranco De Stefano, Daniel Litewczuk, Cristina Mollica, Giuseppe Di Pietro, Eleonora Galosi, Caterina Leone, Pietro Falco, Maria Giulia Tullo, Francesca Caramia, Andrea Truini, Giulia Di Stefano
BACKGROUND: It is well established that trigeminal neuralgia is more prevalent in females than in males. Neurovascular compression with morphological changes of the trigeminal root represents the most recognized etiological factor. However, other factors may play a role in the framework of a multi-hit model. The primary aim of this study was to investigate sex differences in radiological and clinical characteristics of trigeminal neuralgia to better understand the multifactorial origin of this peculiar neuropathic pain condition...
July 12, 2023: Neurological Sciences
https://read.qxmd.com/read/37293433/preclinical-orofacial-pain-assays-and-measures-and-chronic-primary-orofacial-pain-research-where-we-are-and-where-we-need-to-go
#19
REVIEW
Shirin Sadighparvar, Faez Saleh Al-Hamed, Reza Sharif-Naeini, Carolina Beraldo Meloto
Chronic primary orofacial pain (OFP) conditions such as painful temporomandibular disorders (pTMDs; i.e., myofascial pain and arthralgia), idiopathic trigeminal neuralgia (TN), and burning mouth syndrome (BMS) are seemingly idiopathic, but evidence support complex and multifactorial etiology and pathophysiology. Important fragments of this complex array of factors have been identified over the years largely with the help of preclinical studies. However, findings have yet to translate into better pain care for chronic OFP patients...
2023: Front Pain Res (Lausanne)
https://read.qxmd.com/read/37275345/imaging-the-neural-substrate-of-trigeminal-neuralgia-pain-using-deep-learning
#20
JOURNAL ARTICLE
Yun Liang, Qing Zhao, Zhenhong Hu, Ke Bo, Sreenivasan Meyyappan, John K Neubert, Mingzhou Ding
Trigeminal neuralgia (TN) is a severe and disabling facial pain condition and is characterized by intermittent, severe, electric shock-like pain in one (or more) trigeminal subdivisions. This pain can be triggered by an innocuous stimulus or can be spontaneous. Presently available therapies for TN include both surgical and pharmacological management; however, the lack of a known etiology for TN contributes to the unpredictable response to treatment and the variability in long-term clinical outcomes. Given this, a range of peripheral and central mechanisms underlying TN pain remain to be understood...
2023: Frontiers in Human Neuroscience
keyword
keyword
109560
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.