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https://www.readbyqxmd.com/read/28630831/unusual-presentation-of-mycetoma-of-the-foot-a-rare-case-report
#1
Amit Grover, Prashanth Nagaraj, Vinay M Joseph, Daksh Gadi
INTRODUCTION: Mycetoma is a chronic granulomatous infection. It is caused by actinomycetes or fungi. It is common in tropical countries and males. Predisposing conditions include malnutrition, poor hygiene, history of trauma, wounds on barefeet, and systemic infections. Eumycotic mycetoma commonly involves lower extremities whereas actinomycosis affects the cervicofacial, thoracic, and abdominal regions. Mycetoma presents with a chronic indurated ulcerated plague with swelling and yellowish discharge of sulfur granules...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28630117/confronting-the-firearm-injury-plague
#2
Eliot W Nelson
No abstract text is available yet for this article.
June 19, 2017: Pediatrics
https://www.readbyqxmd.com/read/28629124/microbial-diseases-of-bivalve-mollusks-infections-immunology-and-antimicrobial-defense
#3
REVIEW
Carla Zannella, Francesco Mosca, Francesca Mariani, Gianluigi Franci, Veronica Folliero, Marilena Galdiero, Pietro Giorgio Tiscar, Massimiliano Galdiero
A variety of bivalve mollusks (phylum Mollusca, class Bivalvia) constitute a prominent commodity in fisheries and aquacultures, but are also crucial in order to preserve our ecosystem's complexity and function. Bivalve mollusks, such as clams, mussels, oysters and scallops, are relevant bred species, and their global farming maintains a high incremental annual growth rate, representing a considerable proportion of the overall fishery activities. Bivalve mollusks are filter feeders; therefore by filtering a great quantity of water, they may bioaccumulate in their tissues a high number of microorganisms that can be considered infectious for humans and higher vertebrates...
June 17, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28628265/improving-preventive-locust-management-insights-from-a-multi-agent-model
#4
Pierre-Emmanuel Gay, Michel Lecoq, Cyril Piou
BACKGROUND: Preventive management of locust plagues works in some cases but still fails frequently. The role of funding institution awareness was suggested as a potential facilitating factor for cyclic locust plagues. We designed a multi-agent system to represent the events of locust plague development and a management system with three levels: funding institution, national control unit and field teams. A sensitivity analysis identified the limits and improvements of the management system...
June 19, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28628121/universal-quinone-electrodes-for-long-cycle-life-aqueous-rechargeable-batteries
#5
Yanliang Liang, Yan Jing, Saman Gheytani, Kuan-Yi Lee, Ping Liu, Antonio Facchetti, Yan Yao
Aqueous rechargeable batteries provide the safety, robustness, affordability, and environmental friendliness necessary for grid storage and electric vehicle operations, but their adoption is plagued by poor cycle life due to the structural and chemical instability of the anode materials. Here we report quinones as stable anode materials by exploiting their structurally stable ion-coordination charge storage mechanism and chemical inertness towards aqueous electrolytes. Upon rational selection/design of quinone structures, we demonstrate three systems that coupled with industrially established cathodes and electrolytes exhibit long cycle life (up to 3,000 cycles/3,500 h), fast kinetics (≥20C), high anode specific capacity (up to 200-395 mAh g(-1)), and several examples of state-of-the-art specific energy/energy density (up to 76-92 Wh kg(-1)/ 161-208 Wh l(-1)) for several operational pH values (-1 to 15), charge carrier species (H(+), Li(+), Na(+), K(+), Mg(2+)), temperature (-35 to 25 °C), and atmosphere (with/without O2), making them a universal anode approach for any aqueous battery technology...
June 19, 2017: Nature Materials
https://www.readbyqxmd.com/read/28623426/comparative-physical-mapping-of-18s-rdna-in-the-karyotypes-of-six-leafcutter-ant-species-of-the-genera-atta-and-acromyrmex-formicidae-myrmicinae
#6
Gisele Amaro Teixeira, Luísa Antônia Campos Barros, Hilton Jeferson Alves Cardoso de Aguiar, Silvia das Graças Pompolo
Leafcutter ants of the Atta and Acromyrmex genera are important plagues in different cultures. Cytogenetic data on chromosome number, morphology, and chromosomal banding pattern are only available for 17 species of leafcutter ants. Molecular cytogenetic data for the detection of ribosomal genes by the FISH technique are scarce, and only 15 Neotropical ant species have been studied. This study aimed to physically map the 18S ribosomal RNA genes (rDNA) of six leafcutter ants belonging to the genera Atta and Acromyrmex using FISH...
June 16, 2017: Genetica
https://www.readbyqxmd.com/read/28621021/three-dimensional-binder-free-nanoarchitectures-for-advanced-pseudocapacitors
#7
REVIEW
Jianli Kang, Shaofei Zhang, Zhijia Zhang
The ever-increasing energy demands for electrification of transportation and powering of portable electronics are driving the pursuit of energy-storage technologies beyond the current horizon. Pseudocapacitors have emerged as one of the favored contenders to fill in this technology gap, owing to their potential to deliver both high power and energy densities. The high specific capacitance of pseudocapacitive materials is rooted in the various available oxidation states for fast surface or near-surface redox charge transfer...
June 16, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28620271/glutamine-ameliorates-mucosal-damage-caused-by-immune-responses-to-duck-plague-virus
#8
Yuanyuan Zhang, Lili Zhao, Yan Zhou, Chenxi Diao, Lingxia Han, Niu Yinjie, Shengwang Liu, Hongyan Chen
The immune-releasing effects of L-glutamine (Gln) supplementation in duck plague virus (DPV)-infected ducklings were evaluated in 120 seven-day-old ducklings that were divided into 8 groups. The ducklings in control and DPV, 0.5Gln and DPV + 0.5Gln, 1.0Gln and DPV + 1.0Gln, and 2.0Gln and DPV + 2.0Gln received 0, 0.5, 1.0, and 2.0 g of Gln/kg feed/d by gastric perfusion, respectively. Then, the ducklings in control to 2.0Gln were injected with 0.2 mL of phosphate-buffered saline, while those in DPV to DPV + 2...
April 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/28618345/a-nir-controlled-cage-mimicking-system-for-hydrophobic-drug-mediated-cancer-therapy
#9
Chaoqun Liu, Yan Zhang, Min Liu, Zhaowei Chen, Youhui Lin, Wei Li, Fangfang Cao, Zhen Liu, Jinsong Ren, Xiaogang Qu
Most chemotherapeutic drugs commonly suffer from several shortcomings, including the lack of aqueous solubility, limited stability and adverse side effects. Although caging strategy has recently been employed as an effective approach to conceal and stabilize these drugs to achieve light-activated cancer therapy, it is plagued by the sophisticated drug modification process and deleterious solvent usage. In addition, using UV or Visible light to remove photocaged group is restricted to its limited tissue penetration ability in and phototoxicity...
September 2017: Biomaterials
https://www.readbyqxmd.com/read/28617987/the-sex-selective-impact-of-the-black-death-and-recurring-plagues-in-the-southern-netherlands-1349-1450
#10
Daniel R Curtis, Joris Roosen
Although recent work has begun to establish that early modern plagues had selective mortality effects, it was generally accepted that the initial outbreak of Black Death in 1347-52 was a "universal killer." Recent bioarchaeological work, however, has argued that the Black Death was also selective with regard to age and pre-plague health status. The issue of the Black Death's potential sex selectivity is less clear. Bioarchaeological research hypothesizes that sex-selection in mortality was possible during the initial Black Death outbreak, and we present evidence from historical sources to test this notion...
June 15, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28613894/individual-defects-in-inas-ingaassb-gasb-nanowire-tunnel-field-effect-transistors-operating-below-60-mv-decade
#11
Elvedin Memisevic, Markus Hellenbrand, Erik Lind, Axel R Persson, Saurabh Sant, Andreas Schenk, Johannes Svensson, Lars-Erik Wernersson, Lars Reine Wallenberg
Tunneling Field-Effect Transistors (TunnelFET), a leading steep-slope transistor candidate, is still plagued by defect response and there is a large discrepancy between measured and simulated device performance. In this work, highly scaled InAs-InxGa1-xAsySb1-y-GaSb vertical nanowire TunnelFET with ability to operate well below 60 mV/decade at technically relevant currents are fabricated and characterized. The structure, composition, and strain is characterized using transmission electron microscopy with emphasis on the heterojunction...
June 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28612058/vesicoureteral-reflux-and-continuous-prophylactic-antibiotics
#12
REVIEW
Ted Lee, John M Park
Vesicoureteral reflux (VUR) management must be tailored based on the risk for further infections and renal scarring, gender, likelihood of spontaneous resolution, and parental preferences. Because we now understand that sterile VUR is benign and most reflux spontaneously resolves over time, the initial approach in majority of children is non-surgical with continuous antibiotic prophylaxis (CAP) and correction of bladder and bowel dysfunction. Despite increasing utilization of CAP over the past four decades, the efficacy of antibiotic prophylaxis has been questioned due to conflicting results of studies plagued with design flaws and inadequate subject sample size...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28609137/an-attempt-to-develop-a-detection-method-specific-for-virulent-duck-plague-virus-strains-based-on-the-ul2-gene-b-fragment
#13
Liji Xie, Li Huang, Zhixun Xie, Sheng Wang, Jiaoling Huang, Yanfang Zhang, Chuande Zhong
A comparison of the unique long region 2 (UL2) gene sequences between 10 virulent and 11 attenuated duck plague virus (DPV) strains (including all DPV UL2 gene sequences registered in GenBank) showed that the UL2 genes in the attenuated DPV strains had a 528bp deletion in the B fragment. Primers were designed based on the B fragment sequence of the UL2 gene in an attempt to establish a fluorescence quantitative polymerase chain reaction (PCR) and a conventional PCR detection method that could specifically detect virulent DPV strains (i...
June 13, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28607526/a-unified-framework-for-constructing-tuning-and-assessing-photometric-redshift-density-estimates-in-a-selection-bias-setting
#14
P E Freeman, R Izbicki, A B Lee
Photometric redshift estimation is an indispensable tool of precision cosmology. One problem that plagues the use of this tool in the era of large-scale sky surveys is that the bright galaxies that are selected for spectroscopic observation do not have properties that match those of (far more numerous) dimmer galaxies; thus, ill-designed empirical methods that produce accurate and precise redshift estimates for the former generally will not produce good estimates for the latter. In this paper, we provide a principled framework for generating conditional density estimates (i...
July 2017: Monthly Notices of the Royal Astronomical Society
https://www.readbyqxmd.com/read/28606812/novel-ctl-epitopes-identified-through-a-y-pestis-proteome-wide-analysis-in-the-search-for-vaccine-candidates-against-plague
#15
Anat Zvi, Shahar Rotem, Ayelet Zauberman, Uri Elia, Moshe Aftalion, Erez Bar-Haim, Emanuelle Mamroud, Ofer Cohen
The causative agent of Plague, Yersinia pestis, is a highly virulent pathogen and a potential bioweapon. Depending on the route of infection, two prevalent occurrences of the disease are known, bubonic and pneumonic. The latter has a high fatality rate. In the absence of a licensed vaccine, intense efforts to develop a safe and efficacious vaccine have been conducted, and humoral-driven subunit vaccines containing the F1 and LcrV antigens are currently under clinical trials. It is well known that a cellular immune response might have an essential additive value to immunity and protection against Y...
June 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28605463/stereotactic-radiosurgery-and-hypofractionated-radiotherapy-for-glioblastoma
#16
Jennifer L Shah, Gordon Li, Jenny L Shaffer, Melissa I Azoulay, Iris C Gibbs, Seema Nagpal, Scott G Soltys
Glioblastoma is the most common primary brain tumor in adults. Standard therapy depends on patient age and performance status but principally involves surgical resection followed by a 6-wk course of radiation therapy given concurrently with temozolomide chemotherapy. Despite such treatment, prognosis remains poor, with a median survival of 16 mo. Challenges in achieving local control, maintaining quality of life, and limiting toxicity plague treatment strategies for this disease. Radiotherapy dose intensification through hypofractionation and stereotactic radiosurgery is a promising strategy that has been explored to meet these challenges...
June 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28604289/a-suitable-soil-plague-s-urban-breeding-grounds-at-the-dawn-of-the-third-pandemic
#17
Christos Lynteris
A pressing question during the first half-decade of the third plague pandemic (1894-9) was what was a 'suitable soil' for the disease. The question related to plague's perceived ability to disappear from a given city only to reappear at some future point; a phenomenon that became central to scientific investigations of the disease. However, rather than this simply having a metaphorical meaning, the debate around plague's 'suitable soil' actually concerned the material reality of the soil itself. The prevalence of plague in the working-class neighbourhood of Taipingshan during the first major outbreak of the pandemic, in 1894 in Hong Kong, led to an extensive debate regarding the ability of the soil to harbour and even spread the disease...
July 2017: Medical History
https://www.readbyqxmd.com/read/28603999/defect-healing-and-charge-transfer-mediated-valley-polarization-in-mos2-mose2-mos2-trilayer-van-der-waals-heterostructures
#18
Alessandro Surrente, Dumitru Dumcenco, Zhuo Yang, Agnieszka Kuc, Yu Jing, Thomas Heine, Yen-Cheng Kung, Duncan K Maude, Andras Kis, Paulina Plochocka
Monolayer transition metal dichalcogenides (TMDCs) grown by chemical vapor deposition (CVD) are plagued by a significantly lower optical quality compared to exfoliated TMDCs. In this work, we show that the optical quality of CVD-grown MoSe2 is completely recovered if the material is sandwiched in MoS2/MoSe2/MoS2 trilayer van der Waals heterostructures. We show by means of density functional theory that this remarkable and unexpected result is due to defect healing: S atoms of the more reactive MoS2 layers are donated to heal Se vacancy defects in the middle MoSe2 layer...
June 15, 2017: Nano Letters
https://www.readbyqxmd.com/read/28600652/wallerian-demyelination-chronicle-of-a-cellular-cataclysm
#19
REVIEW
Nicolas Tricaud, Hwan Tae Park
Wallerian demyelination is characteristic of peripheral nerve degeneration after traumatic injury. After axonal degeneration, the myelinated Schwann cell undergoes a stereotypical cellular program that results in the disintegration of the myelin sheath, a process termed demyelination. In this review, we chronologically describe this program starting from the late and visible features of myelin destruction and going backward to the initial molecular steps that trigger the nuclear reprogramming few hours after injury...
June 9, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28598813/identification-of-a-novel-atm-inhibitor-with-cancer-cell-specific-radiosensitization-activity
#20
Amy J C Dohmen, Xiaohang Qiao, Anja Duursma, Ruud H Wijdeven, Cor Lieftink, Floor Hageman, Ben Morris, Pasi Halonen, Conchita Vens, Michiel W M van den Brekel, Huib Ovaa, Jacques Neefjes, Charlotte L Zuur
Treatment of advanced head and neck squamous cell carcinoma (HNSCC) is plagued by low survival and high recurrence rates, despite multimodal therapies. Presently, cisplatin or cetuximab is used in combination with radiotherapy which has resulted in minor survival benefits but increased severe toxicities relative to RT alone. This underscores the urgent need for improved tumor-specific radiosensitizers for better control with lower toxicities. In a small molecule screen targeting kinases, performed on three HNSCC cell lines, we identified GSK635416A as a novel radiosensitizer...
May 19, 2017: Oncotarget
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