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https://www.readbyqxmd.com/read/28915423/premature-psychotherapy-termination-in-an-outpatient-treatment-program-for-personality-disorders-a-survival-analysis
#1
Dominick Gamache, Claudia Savard, Sophie Lemelin, Alexandre Côté, Evens Villeneuve
OBJECTIVE: Psychological treatment for patients with personality disorders (PD) is plagued with a high proportion of early dropouts, and attempts to identify risk factors for attrition have generated very few conclusive results. The purpose of the present study is to identify significant predictors of early treatment termination in a long-term psychotherapy program for PD. METHODS: Data was retrospectively retrieved from 174 files of patients who began long-term psychotherapy in an outpatient treatment program in Quebec City, Canada...
August 9, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28915301/the-work-of-us-public-health-service-officers-in-puerto-rico-1898-1919
#2
Jose G Rigau-Pérez
The history of the US Public Health Service (PHS) is usually presented in terms of diseases or discoveries; this article examines twenty years' activity in one location. When the United States invaded Puerto Rico in 1898, the Marine Hospital Service (now PHS) took responsibility for foreign quarantine, inspection of immigrants, and medical care for merchant seamen. Its officers evaluated the sanitary conditions of port cities, helped reorganize local disease surveillance and control, and investigated endemic diseases (e...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28913431/ultrahigh-current-density-anodes-with-interconnected-li-metal-reservoir-through-overlithiation-of-mesoporous-alf3-framework
#3
Hansen Wang, Dingchang Lin, Yayuan Liu, Yuzhang Li, Yi Cui
Lithium (Li) metal is the ultimate solution for next-generation high-energy density batteries but is plagued from commercialization by infinite relative volume change, low Coulombic efficiency due to side reactions, and safety issues caused by dendrite growth. These hazardous issues are further aggravated under high current densities needed by the increasing demand for fast charging/discharging. We report a one-step fabricated Li/Al4Li9-LiF nanocomposite (LAFN) through an "overlithiation" process of a mesoporous AlF3 framework, which can simultaneously mitigate the abovementioned problems...
September 2017: Science Advances
https://www.readbyqxmd.com/read/28905650/a-contextual-behavior-science-framework-for-understanding-how-behavioral-flexibility-relates-to-anxiety
#4
Kathleen M Palm Reed, Amy Y Cameron, Victoria E Ameral
There is a growing literature focusing on the emerging idea that behavioral flexibility, rather than particular emotion regulation strategies per se, provides greater promise in predicting and influencing anxiety-related psychopathology. Yet this line of research and theoretical analysis appear to be plagued by its own challenges. For example, middle-level constructs, such as behavioral flexibility, are difficult to define, difficult to measure, and difficult to interpret in relation to clinical interventions...
September 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/28905259/unintended-pregnancy-induced-abortion-and-mental-health
#5
REVIEW
Sarah Horvath, Courtney A Schreiber
PURPOSE OF REVIEW: The early medical literature on mental health outcomes following abortion is fraught with methodological flaws that can improperly influence clinical practice. Our goal is to review the current medical literature on depression and other mental health outcomes for women obtaining abortions. RECENT FINDINGS: The Turnaway Study prospectively enrolled 956 women seeking abortion in the USA and followed their mental health outcomes for 5 years. The control group was comprised of women denied abortions based on gestational age limits, thereby circumventing the major methodological flaw that had plagued earlier studies on the topic...
September 14, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28904964/plague-a-millenary-infectious-disease-reemerging-in-the-xxi-century
#6
REVIEW
A J Dos Santos Grácio, Maria Amélia A Grácio
Plague, in the Middle Ages known as Black Death, continues to occur at permanent foci in many countries, in Africa, Asia, South America, and even the USA. During the last years outbreaks were reported from at least 3 geographical areas, in all cases after tens of years without reported cases. The recent human plague outbreaks in Libya and Algeria suggest that climatic and other environmental changes in Northern Africa may be favourable for Y. pestis epidemiologic cycle. If so, other Northern Africa countries with plague foci also may be at risk for outbreaks in the near future...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28904707/perspectives-on-utilization-of-community-based-health-information-systems-in-western-kenya
#7
Otieno Careena Flora, Kaseje Margaret, Kaseje Dan
INTRODUCTION: Health information systems (HIS) are considered fundamental for the efficient delivery of high quality health care. However, a large number of legal and practical constraints influence the design and introduction of such systems. The inability to quantify and analyse situations with credible data and to use data in planning and managing service delivery plagues Africa. Establishing effective information systems and using this data for planning efficient health service delivery is essential to district health systems' performance improvement...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28903751/rna-seq-comparative-analysis-of-peking-ducks-spleen-gene-expression%C3%A2-24%C3%A2-h-post-infected-with-duck-plague-virulent-or-attenuated-virus
#8
Tian Liu, Anchun Cheng, Mingshu Wang, Renyong Jia, Qiao Yang, Ying Wu, Kunfeng Sun, Dekang Zhu, Shun Chen, Mafeng Liu, XinXin Zhao, Xiaoyue Chen
Duck plague virus (DPV), a member of alphaherpesvirus sub-family, can cause significant economic losses on duck farms in China. DPV Chinese virulent strain (CHv) is highly pathogenic and could induce massive ducks death. Attenuated DPV vaccines (CHa) have been put into service against duck plague with billions of doses in China each year. Researches on DPV have been development for many years, however, a comprehensive understanding of molecular mechanisms underlying pathogenicity of CHv strain and protection of CHa strain to ducks is still blank...
September 13, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28888767/recent-acute-crayfish-mortality-reveals-aphanomyces-astaci-presence-in-bosnia-and-herzegovina
#9
Mrugała Agata, Šanda Radek, Petrusek Adam, Marić Dario, Vukić Jasna
Although the introduction of the crayfish plague pathogen Aphanomyces astaci to Europe is responsible for substantial declines in native crayfish populations throughout the whole continent, its presence has never been officially confirmed in many European regions, including most of the Balkan Peninsula. We demonstrate that the recent crayfish mortality observed in Bosnia and Herzegovina (Mostarsko blato karst field, Neretva river drainage) was caused by A. astaci. The causative strain is known only from European crayfish, indicating that A...
September 6, 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/28888210/antibody-cytokine-fusion-proteins-for-improving-efficacy-and-safety-of-cancer-therapy
#10
REVIEW
Zahra Valedkarimi, Hadi Nasiri, Leili Aghebati-Maleki, Jafar Majidi
Cytokines are key players in the regulation of immune responses both in physiological and pathological states. A number of cytokines have been evaluated in clinical trials and shown promising results in the treatment of different malignancies. Despite this, the clinical application of these molecules may be plagued by undesirable side effects The development of recombinant antibody-cytokine fusion proteins, which offer a means for target delivery of cytokines toward the tumor site, has significantly improved the therapeutic index of these immunomodulatory molecules...
September 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28887770/optimization-of-1-h-decoupling-eliminates-sideband-artifacts-in-3d-trosy-based-triple-resonance-experiments
#11
Youlin Xia, Paolo Rossi, Marco Tonelli, Chengdong Huang, Charalampos G Kalodimos, Gianluigi Veglia
TROSY-based triple resonance experiments are essential for protein backbone assignment of large biomolecular systems by solution NMR spectroscopy. In a survey of the current Bruker pulse sequence library for TROSY-based experiments we found that several sequences were plagued by artifacts that affect spectral quality and hamper data analysis. Specifically, these experiments produce sidebands in the (13)C(t 1) dimension with inverted phase corresponding to (1)HN resonance frequencies, with approximately 5% intensity of the parent (13)C crosspeaks...
September 8, 2017: Journal of Biomolecular NMR
https://www.readbyqxmd.com/read/28886687/-fleaing-the-plague-adaptations-of-yersinia-pestis-to-its-insect-vector-that-lead-to-transmission
#12
B Joseph Hinnebusch, Clayton O Jarrett, David M Bland
Interest in arthropod-borne pathogens focuses primarily on how they cause disease in humans. How they produce a transmissible infection in their arthropod host is just as critical to their life cycle, however. Yersinia pestis adopts a unique life stage in the digestive tract of its flea vector, characterized by rapid formation of a bacterial biofilm that is enveloped in a complex extracellular polymeric substance. Localization and adherence of the biofilm to the flea foregut is essential for transmission. Here, we review the molecular and genetic mechanisms of these processes and present a comparative evaluation and updated model of two related transmission mechanisms...
September 8, 2017: Annual Review of Microbiology
https://www.readbyqxmd.com/read/28886032/emergence-phenology-uncertainty-and-the-evolution-of-migratory-behavior-in-anax-junius-odonata-aeshnidae
#13
Michael L May, John A Gregoire, Suzanne M Gregoire, Maria Aliberti Lubertazzi, John H Matthews
Mass migrations by Odonata, although less studied than those of Monarch butterflies and plague locusts, have provoked comment and study for many years. Relatively recently, increasing interest in dragonflies, supported by new technologies, has resulted in more detailed knowledge of the species involved, behavioral mechanisms, and geographic extent. In this paper we examine, in four independent but complementary studies, how larval habitat and emergence phenology interact with climate to shape the evolution of migratory strategy in Anax junius, a common species throughout much of the eastern United States and southern Canada...
2017: PloS One
https://www.readbyqxmd.com/read/28885380/use-of-durable-continuous-flow-ventricular-assist-devices-in-patients-on-immunosuppression
#14
Robert A Sorabella, Jiho Han, Veli K Topkara, A Reshad Garan, Melana Yuzefpolskaya, Paolo C Colombo, Koji Takeda, Yoshifumi Naka, Hiroo Takayama
Durable ventricular assist device (VAD) therapy remains an important treatment for end-stage heart failure. Despite advancements in device design, postimplant infectious complications continue to plague this population. In this study, we aim to evaluate the use of durable VAD therapy in patients on active immunosuppression. All patients undergoing durable, continuous-flow VAD placement on active immunosuppression at our center from 2004 to 2012 were included in the analysis (group immunosuppressed [IS]; n = 13)...
September 5, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28879613/vaccines-for-conservation-plague-prairie-dogs-black-footed-ferrets-as-a-case-study
#15
Daniel J Salkeld
The endangered black-footed ferret (Mustela nigripes) is affected by plague, caused by Yersinia pestis, both directly, as a cause of mortality, and indirectly, because of the impacts of plague on its prairie dog (Cynomys spp.) prey base. Recent developments in vaccines and vaccine delivery have raised the possibility of plague control in prairie dog populations, thereby protecting ferret populations. A large-scale experimental investigation across the western US shows that sylvatic plague vaccine delivered in oral baits can increase prairie dog survival...
September 6, 2017: EcoHealth
https://www.readbyqxmd.com/read/28874801/divergent-evolution-of-carbonaceous-aerosols-during-dispersal-of-east-asian-haze
#16
Wenzheng Fang, August Andersson, Mei Zheng, Meehye Lee, Henry Holmstrand, Sang-Woo Kim, Ke Du, Örjan Gustafsson
Wintertime East Asia is plagued by severe haze episodes, characterized by large contributions of carbonaceous aerosols. However, the sources and atmospheric transformations of these major components are poorly constrained, hindering development of efficient mitigation strategies and detailed modelling of effects. Here we present dual carbon isotope (δ(13)C and Δ(14)C) signatures for black carbon (BC), organic carbon (OC) and water-soluble organic carbon (WSOC) aerosols collected in urban (Beijing and BC for Shanghai) and regional receptors (e...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28874081/physicochemical-investigation-and-in-vivo-activity-of-anti-malarial-drugs-co-loaded-in-tween-80-niosomes
#17
Miloni Thakkar, Brijesh S
Drugs used for the treatment and prevention of malaria are often plagued by the problem of development of resistance. This has hampered their therapeutic efficiency and rendered them ineffective for monotherapy. However, if re-packaged and combined properly, many of these neglected anti-malarial drugs can possibly find their way back into the treatment regime. The present study evaluates the use of curcumin (CC) and primaquine (PRI) as an anti-malarial combination, packaged within niosomes, in comparison to their respective monotherapy options...
September 5, 2017: Journal of Liposome Research
https://www.readbyqxmd.com/read/28873421/russian-isolates-enlarge-the-known-geographic-diversity-of-francisella-tularensis-subsp-mediasiatica
#18
Vitalii Timofeev, Irina Bakhteeva, Galina Titareva, Pavel Kopylov, David Christiany, Alexander Mokrievich, Ivan Dyatlov, Gilles Vergnaud
Francisella tularensis, a small Gram-negative bacterium, is capable of infecting a wide range of animals, including humans, and causes a plague-like disease called tularemia-a highly contagious disease with a high mortality rate. Because of these characteristics, F. tularensis is considered a potential agent of biological terrorism. Currently, F. tularensis is divided into four subspecies, which differ in their virulence and geographic distribution. Two of them, subsp. tularensis (primarily found in North America) and subsp...
2017: PloS One
https://www.readbyqxmd.com/read/28873412/temporal-phylogeography-of-yersinia-pestis-in-madagascar-insights-into-the-long-term-maintenance-of-plague
#19
Amy J Vogler, Voahangy Andrianaivoarimanana, Sandra Telfer, Carina M Hall, Jason W Sahl, Crystal M Hepp, Heather Centner, Genevieve Andersen, Dawn N Birdsell, Lila Rahalison, Roxanne Nottingham, Paul Keim, David M Wagner, Minoarisoa Rajerison
BACKGROUND: Yersinia pestis appears to be maintained in multiple, geographically separate, and phylogenetically distinct subpopulations within the highlands of Madagascar. However, the dynamics of these locally differentiated subpopulations through time are mostly unknown. To address that gap and further inform our understanding of plague epidemiology, we investigated the phylogeography of Y. pestis in Madagascar over an 18 year period. METHODOLOGY/PRINCIPAL FINDINGS: We generated whole genome sequences for 31 strains and discovered new SNPs that we used in conjunction with previously identified SNPs and variable-number tandem repeats (VNTRs) to genotype 773 Malagasy Y...
September 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28868095/a-mechanistic-account-of-wide-computationalism
#20
Luke Kersten
The assumption that psychological states and processes are computational in character pervades much of cognitive science, what many call the computational theory of mind. In addition to occupying a central place in cognitive science, the computational theory of mind has also had a second life supporting "individualism", the view that psychological states should be taxonomized so as to supervene only on the intrinsic, physical properties of individuals. One response to individualism has been to raise the prospect of "wide computational systems", in which some computational units are instantiated outside the individual...
2017: Review of Philosophy and Psychology
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