Jierui Wang, Limei Luo, Zirui Meng, Yan Ren, Meng Tang, Zhuochun Huang, Bin Yang, Qian Niu, Dong Zhou, Minjin Wang, Jinmei Li
OBJECTIVES: To investigate the immunopathogenic mechanisms of anti-N-methyl-D-aspartate receptor encephalitis (NMDAR-E) by characterizing the changes of immune cells in both peripheral blood (PB) and cerebrospinal fluid (CSF) of patients with NMDAR-E. METHODS: Cytology and flow cytometry were used to explore and compare different immunological parameters in PB and CSF of patients with NMDAR-E, viral encephalitis (VE) and healthy volunteers. Moreover, different models were established to assess the possibility of identifying NMDAR-E patients based on PB and CSF parameters...
March 1, 2024: International Immunopharmacology