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https://www.readbyqxmd.com/read/28239878/-appeals-to-nature-in-marriage-equality-debates-a-content-analysis-of-newspaper-and-social-media-discourse
#1
Cliodhna O'Connor
In May 2015, Ireland held a referendum to legalize same-sex marriage, which passed with 62% of the vote. This study explores the role played by 'appeals to nature' in the referendum debate. Little research has investigated how biological attributions are spontaneously generated in real-world discourse regarding sexual rights. Through content analysis of newspaper and Twitter discussion of the referendum, this study aims to (1) establish the frequency of appeals to nature and their distribution across the various 'sides' of the debate and (2) analyse the forms these natural claims took and the rhetorical functions they fulfilled...
February 27, 2017: British Journal of Social Psychology
https://www.readbyqxmd.com/read/28239756/culturally-relevant-human-subjects-protection-training-a-case-study-in-community-engaged-research-in-the-united-states
#2
Jennifer Kue, Laura A Szalacha, Mary Beth Happ, Abigail L Crisp, Usha Menon
Non-academic members of research teams, such as community members, can perceive traditional human subjects protection training as lacking in cultural relevance. We present a case exemplar of the development of a human subjects protection training for research staff with limited English proficiency and/or no or limited research experience. Seven modules were adapted for language, cultural examples, etc., from the standard Collaborative Institutional Training Initiative (CITI) human subjects protection training...
February 27, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28238622/validation-of-the-portuguese-severe-respiratory-insufficiency-questionnaire-for-home-mechanically-ventilated-patients
#3
C Ribeiro, D Ferreira, S Conde, P Oliveira, W Windisch
The aim of this study was to develop and validate the professional translation and cultural adaptation of the Portuguese Severe Respiratory Insufficiency (SRI) Questionnaire. The sample was composed of 93 patients (50 male patients, 53.8%) with a mean age of 66.3 years. The most frequent diagnostic groups were chronic obstructive pulmonary disease, obesity hypoventilation syndrome and restrictive chest wall disorders. The patients were asked to fill in both the SRI and SF-36 questionnaires. Factor analysis of the SRI questionnaire was performed leading to an explained variance of 73%, and resulted in 13 components...
February 23, 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/28237106/methods-to-study-chaperone-mediated-autophagy
#4
E Arias
Chaperone-mediated autophagy (CMA), a selective form of degradation of cytosolic proteins in lysosomes, contributes to maintenance of proteostasis and to the cellular adaptation to stress. CMA substrates are selectively recognized and delivered by a cytosolic chaperone to the lysosomal surface, where, upon unfolding, they are internalized through a membrane translocation complex. Defective or dysfunctional CMA has been associated with human pathologies such as neurodegeneration, cancer, immunodeficiency, or diabetes, increasing the overall interest in methods to monitor this selective autophagic pathway...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28237099/assessment-of-glycolytic-flux-and-mitochondrial-respiration-in-the-course-of-autophagic-responses
#5
V Sica, J M Bravo-San Pedro, F Pietrocola, V Izzo, M C Maiuri, G Kroemer, L Galluzzi
Autophagy is an evolutionarily conserved process that mediates prominent homeostatic functions, both at the cellular and organismal level. Indeed, baseline autophagy not only ensures the disposal of cytoplasmic entities that may become cytotoxic upon accumulation, but also contributes to the maintenance of metabolic fitness in physiological conditions. Likewise, autophagy plays a fundamental role in the cellular and organismal adaptation to homeostatic perturbations of metabolic, physical, or chemical nature...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28230713/the-impact-of-ethnic-and-cultural-differences-on-parental-satisfaction-in-the-picu
#6
Qian Wen Sng, Angela H P Kirk, Siti Nur Hanim Buang, Jan Hau Lee
OBJECTIVES: This study examined satisfaction of parents whose children were admitted to the PICU to identify priority areas for improvement. We hypothesized that differences exist in satisfaction of parents of different ethnicities. DESIGN: Prospective observational study. SETTING: PICU in a tertiary care pediatric hospital. PATIENTS: All English-literate parents whose child was admitted to our PICU between February 2014 and February 2015 were eligible after informed consent was obtained...
February 20, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28229417/a-simplified-and-systematic-method-to-isolate-culture-and-characterize-multiple-types-of-human-dental-stem-cells-from-a-single-tooth
#7
Mohammed Bakkar, Younan Liu, Dongdong Fang, Camille Stegen, Xinyun Su, Murali Ramamoorthi, Li-Chieh Lin, Takako Kawasaki, Nicholas Makhoul, Huan Pham, Yoshinori Sumita, Simon D Tran
This chapter describes a simplified method that allows the systematic isolation of multiple types of dental stem cells such as dental pulp stem cells (DPSC), periodontal ligament stem cells (PDLSC), and stem cells of the apical papilla (SCAP) from a single tooth. Of specific interest is the modified laboratory approach to harvest/retrieve the dental pulp tissue by minimizing trauma to DPSC by continuous irrigation, reduction of frictional heat from the bur rotation, and reduction of the bur contact time with the dentin...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28228972/emergency-preparedness-and-management-at-the-university-of-l-aquila-central-italy-and-the-role-of-students-associations-in-the-april-6th-2009-earthquake
#8
Michele Magni, Rita Fraboni, Fausto Marincioni
INTRODUCTION: On April 6th 2009 an earthquake of Mw=6.3 hit the historical downtown of L'Aquila and its hinterland causing more than 300 fatalities and severe damage to private and public buildings. At the time, the University of L'Aquila represented a major source of employment and income for the city. The earthquake impacted both the facilities and the administrative, financial and patrimonial activities of the university, bringing into the open the tendency - widespread in Italy - to rely on adaptive tactics rather than on strategic pre-disaster plans...
January 12, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28228841/an-update-on-the-management-of-breast-cancer-in-africa
#9
REVIEW
V Vanderpuye, S Grover, N Hammad, PoojaPrabhakar, H Simonds, F Olopade, D C Stefan
BACKGROUND: There is limited information about the challenges of cancer management and attempts at improving outcomes in Africa. Even though South and North Africa are better resourceds to tackle the burden of breast cancer, similar poor prognostic factors are common to all countries. The five-year overall Survival rate for breast cancer patients does not exceed 60% for any low and middle-income country (LMIC) in Africa. In spite of the gains achieved over the past decade, certain characteristics remain the same such as limited availability of breast conservation therapies, inadequate access to drugs, few oncology specialists and adherence to harmful socio-cultural practices...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28228769/toward-an-evolved-concept-of-landrace
#10
Francesc Casañas, Joan Simó, Joan Casals, Jaime Prohens
The term "landrace" has generally been defined as a cultivated, genetically heterogeneous variety that has evolved in a certain ecogeographical area and is therefore adapted to the edaphic and climatic conditions and to its traditional management and uses. Despite being considered by many to be inalterable, landraces have been and are in a constant state of evolution as a result of natural and artificial selection. Many landraces have disappeared from cultivation but are preserved in gene banks. Using modern selection and breeding technology tools to shape these preserved landraces together with the ones that are still cultivated is a further step in their evolution in order to preserve their agricultural significance...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28227795/simplified-realistic-human-head-model-for-simulating-tumor-treating-fields-ttfields
#11
Cornelia Wenger, Ze'ev Bomzon, Ricardo Salvador, Peter J Basser, Pedro C Miranda, Cornelia Wenger, Ze'ev Bomzon, Ricardo Salvador, Peter J Basser, Pedro C Miranda, Peter J Basser, Pedro C Miranda, Cornelia Wenger, Ricardo Salvador, Ze'ev Bomzon
Tumor Treating Fields (TTFields) are alternating electric fields in the intermediate frequency range (100-300 kHz) of low-intensity (1-3 V/cm). TTFields are an anti-mitotic treatment against solid tumors, which are approved for Glioblastoma Multiforme (GBM) patients. These electric fields are induced non-invasively by transducer arrays placed directly on the patient's scalp. Cell culture experiments showed that treatment efficacy is dependent on the induced field intensity. In clinical practice, a software called NovoTal(TM) uses head measurements to estimate the optimal array placement to maximize the electric field delivery to the tumor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226863/synaptic-depression-depends-on-charge-delivered-to-network
#12
Robert D Graham, Sharon Jose, Alex Kaiser, Nathalia Peixoto, Robert D Graham, Sharon Jose, Alex Kaiser, Nathalia Peixoto, Sharon Jose, Alex Kaiser, Robert D Graham, Nathalia Peixoto
In vitro neuronal networks cultured on microelectrode arrays enable the study of network electrophysiology on a fundamental level. Neuronal response to electrical stimulation is an area of interest at the laboratory bench and in the clinic, given its wide application for remedying neurological disorders. Here we investigated the change in cortical network response over time to varied amounts of charge used for stimulation, which may lead to a phenomenon known as selective adaptation. There is a charge threshold that invokes a reverberating network response; when stimulating at 900 mV, five stimulation electrodes were required to elicit a response across the entire network...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226195/global-transcriptional-response-of-human-liver-cells-to-ethanol-stress-of-different-strength-reveals-hormetic-behavior
#13
Wolfgang Schmidt-Heck, Eva C Wönne, Thomas Hiller, Uwe Menzel, Dirk Koczan, Georg Damm, Daniel Seehofer, Fanny Knöspel, Nora Freyer, Reinhard Guthke, Steven Dooley, Katrin Zeilinger
BACKGROUND: The liver is the major site for alcohol metabolism in the body and therefore, the primary target organ for ethanol-induced toxicity. In this study, we investigated the in vitro response of human liver cells to different ethanol concentrations in a perfused bioartificial liver device that mimics the complex architecture of the natural organ. METHODS: Primary human liver cells were cultured in the bioartificial liver device and treated for 24 hours with medium containing 150 mM (low), 300 mM (medium) or 600 mM (high) ethanol, while a control culture was kept untreated...
February 22, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28226041/evaluation-of-the-hospital-accreditation-program-face-and-content-validation
#14
Graziela Caldana, Carmen Silvia Gabriel
Objective: to describe the results of face and content validation of the questionnaire entitled Quality Improvement Implementation Survey, and of two complementary scales as part of the adaptation process to the Brazilian language and culture. Method: included the following stages: (1) translation and synthesis of translations; (2) consideration by the expert committee; (3) back translation; (4) evaluation of verbal understanding by the target population. Results: the questionnaire was translated into Portuguese and its final version included 90 items...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28225878/the-p-a-c-i-e-n-t-e-protocol-an-instrument-for-breaking-bad-news-adapted-to-the-brazilian-medical-reality
#15
Carolina Rebello Pereira, Marco Antônio Marchetti Calônego, Lino Lemonica, Guilherme Antonio Moreira de Barros
OBJECTIVE: There are plenty of published tools for breaking bad medical news; however, none of them is culturally appropriate to our reality or published in the Brazilian literature. This study proposes a genuinely Brazilian communication tool and evaluates its acceptance among doctors and nurses. METHOD: This was a prospective study. The data were collected after specific training of doctors and nurses on the bad news communication techniques based on the P-A-C-I-E-N-T-E ("patient," in Portuguese) Protocol...
January 1, 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28225802/effect-of-various-nitrogen-conditions-on-population-growth-temporary-cysts-and-cellular-biochemical-compositions-of-karenia-mikimotoi
#16
Yan Zhao, Xuexi Tang, Xiaowei Zhao, You Wang
The harmful algal bloom (HAB)-forming dinoflagellate Karenia mikimotoi was exposed to different nitrogen (N) conditions, in order to study the population growth, temporary cyst production and cellular biochemical compositions in laboratory. The results indicated the population growth of K. mikimotoi was inhibited by different levels of N starvation but showed similar fast recovery after the resupplement of N, and temporary cysts were induced in the period of N starvation. K. mikimotoi grew well in inorganic (NO3-, NO2- and NH4+) and organic (urea) nitrogen sources, but the growth parameters (K, Tp, r) showed differences when simulated by Logistic model regressions...
2017: PloS One
https://www.readbyqxmd.com/read/28225616/a-straightforward-approach-for-3d-bacterial-printing
#17
Benjamin A E Lehner, Dominik T Schmieden, Anne Sara Meyer
Sustainable and personally tailored materials production is an emerging challenge to society. Living organisms can produce and pattern an extraordinarily wide range of different molecules in a sustainable way. These natural systems offer an abundant source of inspiration for the development of new environmentally-friendly materials production techniques. In this paper, we describe the first steps towards the 3-dimensional printing of bacterial cultures for materials production and patterning. This methodology combines the capability of bacteria to form new materials with the reproducibility and tailored approach of 3D printing systems...
February 22, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28225536/reliability-and-cross-cultural-adaptation-of-the-turkish-version-of-the-spinal-cord-injury-spasticity-evaluation-tool
#18
Pinar Akpinar, Arzu Atici, Kubra N Kurt, Feyza U Ozkan, Ilknur Aktas, Duygu G Kulcu
The Spinal Cord Injury Spasticity Evaluation Tool is a 7-day recall self-reported questionnaire that assesses the problematic and useful effects of spasticity on daily life in patients with spinal cord injury (SCI). We aimed to determine the reliability and cross-cultural validation of the Turkish translation of the Spinal Cord Injury Spasticity Evaluation Tool (SCI-SETT). After translation and back translation of the Spinal Cord Injury Spasticity Evaluation Tool, 66 patients between the ages of 18 and 88 years with SCI, American Spinal Injury Association impairment scale grades from A to D with spasticity, and at least 6 months after injury were assessed...
February 20, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28225443/bringing-big-data-to-the-forefront-of-healthcare-delivery-the-experience-of-carolinas-healthcare-system
#19
Michael F Dulin, Carol A Lovin, Jean A Wright
The use of big data to transform care delivery is rapidly becoming a reality. To deliver on the promise of value-based care, providers must know the key drivers of wellness at the patient and community levels, as well as understand resource constraints and opportunities to improve efficiency in the health-care system itself. Data are the linchpin. By gathering the right data and finding innovative ways to glean knowledge, we can improve clinical care, advance the health of our communities, improve the lives of our patients, and operate more efficiently...
January 2017: Frontiers of Health Services Management
https://www.readbyqxmd.com/read/28224095/culturally-adapted-pictorial-screening-tool-for-autism-spectrum-disorder-a-new-approach
#20
Hemamali Perera, Kamal Chandima Jeewandara, Sudarshi Seneviratne, Chandima Guruge
AIM: To assess the performance of a newly designed, culturally adapted screening tool for autism spectrum disorder (ASD). METHODS: Items for the screening tool were modeled from already documented checklists and diagnostic criteria for ASD. Each item in text was paired with a photograph that illustrated the written content, which was in the 2 main local languages. The final product had 21 items and was named the pictorial autism assessment schedule (PAAS). Performance of PAAS was tested on a clinical sample of 18-48 mo old children, diagnosis naïve, presenting with developmental deficits...
February 8, 2017: World Journal of Clinical Pediatrics
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