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Cultural adaptation

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https://www.readbyqxmd.com/read/28813068/cultural-adaptation-of-the-short-self-regulation-questionnaire-suggestions-for-the-speech-area
#1
Anna Alice Almeida, Mara Behlau
Purpose: To present the translated and linguistic and culturally adapted version of the Short self-regulation Questionnaire (SSRQ) for the Brazilian Portuguese and to check its applicability to patients with dysphonia. Methods: The SSRQ is a tool used to evaluate the ability to self-regulate behavior; it has 31 items and generates three scores: total index of individual self-regulation capacity and partial scores for goal setting and impulse control. Each item should be scored by means of a Likert-type 5-point scale; the total score ranges from 29 to 145 points...
August 14, 2017: CoDAS
https://www.readbyqxmd.com/read/28812935/motivations-for-learning-of-family-medicine-residents-trained-in-competency-based-education
#2
Oksana Babenko, Olga Szafran, Sudha Koppula, Lillian Au
BACKGROUND AND OBJECTIVE: Family physicians regularly encounter clinical uncertainty and ambiguity and thus, are expected to engage in on-going learning to respond to changing needs of family practice. Using Achievement Goal Theory, the objective of this study was to examine motivations for learning of family medicine residents in a competency-based program. METHOD: This was a cross-sectional study, employing a survey methodology with family medicine residents at the mid-point of training at a Canadian university...
August 16, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28812739/frequency-dependent-female-genital-cutting-behaviour-confers-evolutionary-fitness-benefits
#3
Janet A Howard, Mhairi A Gibson
Female genital cutting (FGC) has immediate and long-term negative health consequences that are well-documented, and its elimination is a priority for policymakers. The persistence of this widespread practice also presents a puzzle for evolutionary anthropologists due to its potentially detrimental impact on survival and reproductive fitness. Using multilevel modelling on demographic health survey datasets from five West African countries, here we show that FGC behaviour is frequency-dependent; the probability that girls are cut varies in proportion to the FGC frequency found in their ethnic group...
February 6, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812250/miv-150-and-zinc-acetate-combination-provides-potent-and-broad-activity-against-hiv-1
#4
Olga Mizenina, Mayla Hsu, Ninochka Jean-Pierre, Meropi Aravantinou, Keith Levendosky, Gabriela Paglini, Thomas M Zydowsky, Melissa Robbiani, José A Fernández-Romero
We previously showed that the combination of the non-nucleoside reverse transcriptase inhibitor (NNRTI) MIV-150 with zinc acetate (ZA) formulated in a carrageenan (CG; MZC) gel provided macaques significant protection against vaginal simian-human immunodeficiency virus-RT (SHIV-RT) challenge, better than either MIV-150/CG or ZA/CG. The MZC gel was shown to be safe in a phase 1 clinical trial. Herein, we used in vitro approaches to study the antiviral properties of ZA and the MIV-150/ZA combination, compared to other NNRTIs...
August 15, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28811613/transcriptomic-analysis-of-nickel-exposure-in-sphingobium-sp-ba1-cells-using-rna-seq
#5
M Volpicella, C Leoni, C Manzari, M Chiara, E Picardi, E Piancone, F Italiano, A D'Erchia, M Trotta, D S Horner, G Pesole, L R Ceci
Nickel acts as cofactor for a number of enzymes of many bacteria species. Its homeostasis is ensured by proteins working as ion efflux or accumulation systems. These mechanisms are also generally adopted to counteract life-threatening high extra-cellular Ni(2+) concentrations. Little is known regarding nickel tolerance in the genus Sphingobium. We studied the response of the novel Sphingobium sp. ba1 strain, able to adapt to high Ni(2+) concentrations. Differential gene expression in cells cultured in 10 mM Ni(2+), investigated by RNA-seq analysis, identified 118 differentially expressed genes...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809452/neurotoxin-synthesis-is-positively-regulated-by-the-sporulation-transcription-factor-spo0a-in-clostridium-botulinum-type-e
#6
Gerald Mascher, Anna Mertaoja, Hannu Korkeala, Miia Lindström
Clostridium botulinum produces the most potent natural toxin, the botulinum neurotoxin (BoNT), probably to create anaerobiosis and nutrients by killing the host, and forms endospores that facilitate survival in harsh conditions and transmission. Peak BoNT production coincides with initiation of sporulation in C. botulinum cultures, which suggests common regulation. Here we show that Spo0A, the master regulator of sporulation, positively regulates BoNT production. Insertional inactivation of spo0A in C. botulinum type E strain Beluga resulted in significantly reduced BoNT production and in abolished or highly reduced sporulation in relation to wild-type controls...
August 15, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28809151/the-pentameric-complex-of-human-cytomegalovirus-cell-tropism-virus-dissemination-immune-response-and-vaccine-development
#7
Giuseppe Gerna, Maria Grazia Revello, Fausto Baldanti, Elena Percivalle, Daniele Lilleri
Between the 1980s and 1990s, three assays were developed for diagnosis of human cytomegalovirus (HCMV) infections: leuko (L)-antigenemia, l-viremia and l-DNAemia, detecting viral protein pp65, infectious virus and viral DNA, respectively, in circulating leukocytes Repeated initial attempts to reproduce the three assays in vitro using laboratory-adapted strains and infected cell cultures were consistently unsuccessful. Results were totally reversed when wild-type HCMV strains were used to infect either fibroblasts or endothelial cells...
August 15, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28809029/model-clades-versus-model-species-anolis-lizards-as-an-integrative-model-of-anatomical-evolution
#8
Thomas J Sanger, Bonnie K Kircher
Anolis lizards , known for their replicated patterns of morphological diversification, are widely studied in the fields of evolution and ecology. As a textbook example of adaptive radiation, this genus has supported decades of intense study in natural history, behavior, morphological evolution, and systematics. Following the publication of the A. carolinensis genome, research on Anolis lizards has expanded into new areas, toward obtaining an understanding the developmental and genetic bases of anole diversity...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28808690/the-hemagglutinin-esterase-fusion-glycoprotein-is-a-primary-determinant-of-the-exceptional-thermal-and-acid-stability-of-influenza-d-virus
#9
Jieshi Yu, Busha Hika, Runxia Liu, Zizhang Sheng, Ben M Hause, Feng Li, Dan Wang
Influenza D virus (IDV) is unique among four types of influenza viruses in that it utilizes cattle as a primary reservoir. The thermal and acid stability of IDV were examined and directly compared with those of influenza A virus (IAV), influenza B virus (IBV), and influenza C virus (ICV). The results of our experiments demonstrated that only IDV had a high residual infectivity (~2.5 log units of 50% tissue culture infective dose [TCID50]/ml) after a 60-min exposure to 53°C in solution at a neutral pH, and remarkably, IDV retained this infectivity even after exposure to 53°C for 120 min...
July 2017: MSphere
https://www.readbyqxmd.com/read/28808412/cross-cultural-adaptation-translation-and-validation-of-the-toronto-extremity-salvage-score-for-extremity-bone-and-soft-tissue-tumor-patients-in-netherlands
#10
Julie J Willeumier, C W P G van der Wal, Robert J P van der Wal, P D S Dijkstra, Thea P M Vliet Vlieland, Michiel A J van de Sande
PURPOSE: The aim of this study was to translate and culturally adapt the Toronto Extremity Salvage Score (TESS) to Dutch and to validate the translated version. METHODS: The TESS lower and upper extremity versions (LE and UE) were translated to Dutch according to international guidelines. The translated version was validated in 98 patients with surgically treated bone or soft tissue tumors of the LE or UE. To assess test-retest reliability, participants were asked to fill in a second questionnaire after one week...
2017: Sarcoma
https://www.readbyqxmd.com/read/28808237/coding-and-small-non-coding-transcriptional-landscape-of-tuberous-sclerosis-complex-cortical-tubers-implications-for-pathophysiology-and-treatment
#11
James D Mills, Anand M Iyer, Jackelien van Scheppingen, Anika Bongaarts, Jasper J Anink, Bart Janssen, Till S Zimmer, Wim G Spliet, Peter C van Rijen, Floor E Jansen, Martha Feucht, Johannes A Hainfellner, Pavel Krsek, Josef Zamecnik, Katarzyna Kotulska, Sergiusz Jozwiak, Anna Jansen, Lieven Lagae, Paolo Curatolo, David J Kwiatkowski, R Jeroen Pasterkamp, Ketharini Senthilkumar, Lars von Oerthel, Marco F Hoekman, Jan A Gorter, Peter B Crino, Angelika Mühlebner, Brendon P Scicluna, Eleonora Aronica
Tuberous Sclerosis Complex (TSC) is a rare genetic disorder that results from a mutation in the TSC1 or TSC2 genes leading to constitutive activation of the mechanistic target of rapamycin complex 1 (mTORC1). TSC is associated with autism, intellectual disability and severe epilepsy. Cortical tubers are believed to represent the neuropathological substrates of these disabling manifestations in TSC. In the presented study we used high-throughput RNA sequencing in combination with systems-based computational approaches to investigate the complexity of the TSC molecular network...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28808030/oxytocin-enforced-norm-compliance-reduces-xenophobic-outgroup-rejection
#12
Nina Marsh, Dirk Scheele, Justin S Feinstein, Holger Gerhardt, Sabrina Strang, Wolfgang Maier, René Hurlemann
Never before have individuals had to adapt to social environments defined by such magnitudes of ethnic diversity and cultural differentiation. However, neurobiological evidence informing about strategies to reduce xenophobic sentiment and foster altruistic cooperation with outsiders is scarce. In a series of experiments settled in the context of the current refugee crisis, we tested the propensity of 183 Caucasian participants to make donations to people in need, half of whom were refugees (outgroup) and half of whom were natives (ingroup)...
August 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28807698/-cross-cultural-adaptation-and-psychometric-evaluation-of-the-turkish-version-of-the-cancer-behavior-inventory-brief-version
#13
Emine Iyigun, Sevinc Tastan, Elif Gezginci, Serap Korkmaz, Selcuk Demiral, Murat Beyzadeoglu
CONTEXT: Cancer Behavior Inventory-Brief Version is a simple and non-burdensome tool used to evaluate the self-efficacy of the cancer patients. OBJECTIVES: The aim of this study was to examine the psychometric properties of the Turkish version of the Cancer Behavior Inventory-Brief Version. METHODS: This methodological study was conducted on 143 cancer patients who received radiotherapy at the Department of Radiation Oncology at a Training and Research Hospital in Turkey...
August 11, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28807411/timp3-is-regulated-by-pericytes-upon-shear-stress-detection-leading-to-a-modified-endothelial-cell-response
#14
C Schrimpf, T Koppen, J S Duffield, U Böer, S David, W Ziegler, A Haverich, O E Teebken, M Wilhelmi
OBJECTIVES: Atherosclerosis is a hallmark of cardiovascular disease. Shear stress on endothelial cells has been linked to atherogenesis and to fibrous cap thinning and rupture. Pericytes reside in the sub-endothelial space of vessels and have vasoprotective effects. They are subjected to shear stress when endothelial cell integrity is disrupted. The aim was to investigate the susceptibility and response of pericytes to shear stress. METHODS: Endothelial cells and pericytes were seeded in two dimensional monocultures and co-cultures, and in a novel three dimensional co-culture system and were subjected to no, low and high shear stress (0, 10, 30 dyne/cm(2)) for 48 h...
August 11, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28807332/synthetic-biology-regulation-and-governance-lessons-from-tapic-for-the-united-states-european-union-and-singapore
#15
Benjamin D Trump
Synthetic biology is an emerging technology with potential benefits to various fields, yet also contains potential risks to human and environmental health. The field remains in an emerging state with limited quantitative guidance and a small but growing population of international researchers that conduct work within this field. Given the uncertain nature of this technology, an adaptive and anticipatory governance framework may be necessary to balance the potential benefits that may accrue from the technology's continued research alongside a desire to reduce or eliminate potential risks that may arise...
August 2, 2017: Health Policy
https://www.readbyqxmd.com/read/28806483/mandate-for-the-nursing-profession-to-address-climate-change-through-nursing-education
#16
Jeanne Leffers, Ruth McDermott Levy, Patrice K Nicholas, Casey F Sweeney
PURPOSE: The adverse health effects from climate change demand action from the nursing profession. This article examines the calls to action, the status of climate change in nursing education, and challenges and recommendations for nursing education related to climate change and human health. ORGANIZING CONSTRUCT: Discussion paper. FINDINGS: The integration of climate change into nursing education is essential so that knowledge, skills, and insights critical for clinical practice in our climate-changing world are incorporated in curricula, practice, research, and policy...
August 14, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28805418/adaptation-of-a-nursing-home-culture-change-research-instrument-for-frontline-staff-quality-improvement-use
#17
Christine W Hartmann, Jennifer A Palmer, Whitney L Mills, Camilla B Pimentel, Rebecca S Allen, Nancy J Wewiorski, Kristen R Dillon, A Lynn Snow
Enhanced interpersonal relationships and meaningful resident engagement in daily life are central to nursing home cultural transformation, yet these critical components of person-centered care may be difficult for frontline staff to measure using traditional research instruments. To address the need for easy-to-use instruments to help nursing home staff members evaluate and improve person-centered care, the psychometric method of cognitive-based interviewing was used to adapt a structured observation instrument originally developed for researchers and nursing home surveyors...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28805414/a-culturally-adapted-family-intervention-for-rural-pacific-island-veterans-with-ptsd
#18
Julia M Whealin, Athena C Yoneda, Dawna Nelson, Todd S Hilmes, Michelle M Kawasaki, Oscar H Yan
The Veterans Affairs mission to provide equitable, accessible, and patient-centered care necessitates that culturally appropriate interventions are available when cultural differences may jeopardize engagement in care. However, within the VA, wounded warriors residing in rural areas in the Pacific Islands have been offered interventions that were developed and tested using largely urban mainland populations. The objectives of this article were to (a) document the cultural adaptation of a cognitive-behavioral clinical intervention for use by rural Pacific Island veterans, and (b) report feasibility data for the intervention...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28803884/challenging-the-colonisation-of-birth-koori-women-s-birthing-knowledge-and-practice
#19
Karen Adams, Shannon Faulkhead, Rachel Stanfield, Petah Atkinson
BACKGROUND: The 2007 United Nations Declaration on the Rights of Indigenous Peoples states that Indigenous peoples have the right to self-determination for social and cultural development. This fundamental right has been impeded worldwide through colonisation where many Indigenous peoples have had to adapt to ensure continuation of cultural knowledge and practice. In South East Australia colonisation was particularly brutal interrupting a 65,000 year-old oral culture and archives have increasing importance for cultural revival...
August 10, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28803615/spanish-cultural-adaptation-of-the-questionnaire-early-arthritis-for-psoriatic-patients
#20
J García-Gavín, L Pérez-Pérez, I Tinazzi, D Vidal, D McGonagle
INTRODUCTION AND OBJECTIVES: The Early Arthritis for Psoriatic patients (EARP) questionnaire is a screening tool for psoriatic arthritis with good measuring properties in its original Italian version but has not been culturally adapted to Spanish. This article presents the adaptation for Spanish population, prior to validation step. MATERIAL AND METHOD: Application of the methodology recommended by the International Society Pharmacoeconomic and Outcome Research for cultural adaptations of measures focused on the patient and comprising the steps of: preparation, translation, reconciliation, back translation and review, harmonization, cognitive debriefing and review, proofreading...
August 10, 2017: Actas Dermo-sifiliográficas
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