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Cultural adaptation

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https://www.readbyqxmd.com/read/28102790/an-adaptable-instrument-and-method-for-exploring-care-and-compassion
#1
Roger Newham, Louise Terry
Background Narratives, particularly when visual and auditory elements are added to words, reveal more about cultures and behaviours, including those present in professional and service settings. Discourse analysis (DA) enables researchers to explicate meanings and understandings linking culture and behaviour. Aim To explain the development of a DA instrument and method for a research study of caring and compassion as expressed in different media. Discussion The DA instrument assisted in systematic and multi-modal data analysis by several researchers from different countries and backgrounds...
January 23, 2017: Nurse Researcher
https://www.readbyqxmd.com/read/28101845/feasibility-acceptability-and-preliminary-treatment-outcomes-in-a-school-based-cbt-intervention-program-for-adolescents-with-asd-and-anxiety-in-singapore
#2
Irene E Drmic, Mariam Aljunied, Judy Reaven
Adolescents with autism spectrum disorder (ASD) are at high risk for anxiety difficulties and disorders. Clinic-based cognitive behavioral therapy (CBT) is effective; however, few published school-based CBT programs for youth with ASD exist. In this study, the Facing Your Fears CBT protocol was adapted for delivery and piloted within a school setting by non-clinicians, with culturally appropriate adaptations. 44 13-15 aged youth with ASD from 22 mainstream schools in Singapore participated. Feasibility, acceptability and preliminary treatment outcomes were examined...
January 18, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28100643/fluid-shear-stress-increases-transepithelial-transport-of-ca2-in-ciliated-distal-convoluted-and-connecting-tubule-cells
#3
Sami G Mohammed, Francisco J Arjona, Femke Latta, René J M Bindels, Ronald Roepman, Joost G J Hoenderop
In kidney, transcellular transport of Ca(2+) is mediated by transient receptor potential vanilloid 5 and Na(+)-Ca(2+) exchanger 1 proteins in distal convoluted and connecting tubules (DCT and CNT, respectively). It is not yet understood how DCT/CNT cells can adapt to differences in tubular flow rate and, consequently, Ca(2+) load. This study aims to elucidate the molecular mechanisms by which DCT/CNT cells sense fluid dynamics to control transepithelial Ca(2+) reabsorption and whether their primary cilia play an active role in this process...
January 18, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28100438/high-dose-rifampicin-moxifloxacin-and-sq109-for-treating-tuberculosis-a-multi-arm-multi-stage-randomised-controlled-trial
#4
Martin J Boeree, Norbert Heinrich, Rob Aarnoutse, Andreas H Diacon, Rodney Dawson, Sunita Rehal, Gibson S Kibiki, Gavin Churchyard, Ian Sanne, Nyanda E Ntinginya, Lilian T Minja, Robert D Hunt, Salome Charalambous, Madeleine Hanekom, Hadija H Semvua, Stellah G Mpagama, Christina Manyama, Bariki Mtafya, Klaus Reither, Robert S Wallis, Amour Venter, Kim Narunsky, Anka Mekota, Sonja Henne, Angela Colbers, Georgette Plemper van Balen, Stephen H Gillespie, Patrick P J Phillips, Michael Hoelscher
BACKGROUND: Tuberculosis is the world's leading infectious disease killer. We aimed to identify shorter, safer drug regimens for the treatment of tuberculosis. METHODS: We did a randomised controlled, open-label trial with a multi-arm, multi-stage design. The trial was done in seven sites in South Africa and Tanzania, including hospitals, health centres, and clinical trial centres. Patients with newly diagnosed, rifampicin-sensitive, previously untreated pulmonary tuberculosis were randomly assigned in a 1:1:1:1:2 ratio to receive (all orally) either 35 mg/kg rifampicin per day with 15-20 mg/kg ethambutol, 20 mg/kg rifampicin per day with 400 mg moxifloxacin, 20 mg/kg rifampicin per day with 300 mg SQ109, 10 mg/kg rifampicin per day with 300 mg SQ109, or a daily standard control regimen (10 mg/kg rifampicin, 5 mg/kg isoniazid, 25 mg/kg pyrazinamide, and 15-20 mg/kg ethambutol)...
January 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28100299/pathogenicity-of-modified-bat-influenza-virus-with-different-m-genes-and-its-reassortment-potential-with-swine-influenza-a-virus
#5
Jianmei Yang, Jinhwa Lee, Jingjiao Ma, Yuekun Lang, Jerome Nietfeld, Yuhao Li, Michael Duff, Yonghai Li, Yuju Yang, Haixia Liu, Bin Zhou, David E Wentworth, Juergen A Richt, Zejun Li, Wenjun Ma
In our previous studies the reassortant virus containing only the PR8 H1N1 matrix (M) gene in the background of the modified bat influenza Bat09:mH1mN1 virus could be generated. However, whether M genes from other origins can be rescued in the background of the Bat09:mH1mN1 virus and whether the resulting novel reassortant virus is virulent remain unknown. Herein, two reassortant viruses were generated in the background of the Bat09:mH1mN1 virus containing either a North American or a Eurasian swine influenza virus M gene...
January 18, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28099953/social-networks-among-the-older-chinese-population-in-the-usa-findings-from-the-pine-study
#6
XinQi Dong, E-Shien Chang
BACKGROUND: Social network research has become central to studies of health and aging. Its results may yield public health insights that are actionable and improve the quality of life of older adults. However, little is known about the social networks of older immigrant adults, whose social relationships often develop in the context of migration, compounded by cultural and linguistic barriers. OBJECTIVES: This report aims to describe the structure, composition, and emotional components of social networks in the Chinese aging population of the USA, and to explore ways in which their social networks may be critical to their health decision-making...
January 19, 2017: Gerontology
https://www.readbyqxmd.com/read/28099561/macarthur-competence-assessment-tool-for-treatment-in-alzheimer-disease-cross-cultural-adaptation
#7
Raquel Luiza Santos, Maria Fernanda Barroso de Sousa, José Pedro Simões, Elodie Bertrand, Daniel C Mograbi, Jesus Landeira-Fernandez, Jerson Laks, Marcia Cristina Nascimento Dourado
Objective: We adapted the MacArthur Competence Assessment Tool for Treatment (MacCAT-T) to Brazilian Portuguese, pilot testing it on mild and moderate patients with Alzheimer's disease (AD). Methods: The cross-cultural process required six steps. Sixty-six patients with AD were assessed for competence to consent to treatment, global cognition, working memory, awareness of disease, functionality, depressive symptoms and dementia severity. Results: The items had semantic, idiomatic, conceptual and experiential equivalence...
January 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28098628/the-abcdef-bundle-science-and-philosophy-of-how-icu-liberation-serves-patients-and-families
#8
E Wesley Ely
Over the past 20 years, critical care has matured in a myriad of ways resulting in dramatically higher survival rates for our sickest patients. For millions of new survivors comes de novo suffering and disability called "the postintensive care syndrome." Patients with postintensive care syndrome are robbed of their normal cognitive, emotional, and physical capacity and cannot resume their previous life. The ICU Liberation Collaborative is a real-world quality improvement initiative being implemented across 76 ICUs designed to engage strategically the ABCDEF bundle through team- and evidence-based care...
February 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28098504/effects-of-culturally-adaptive-walking-intervention-on-cardiovascular-disease-risks-for-middle-aged-korean-chinese-female-migrant-workers
#9
Hyeonkyeong Lee, Sunghye Cho, JoEllen Wilbur, Jung Hee Kim, Chang-Gi Park, Young-Me Lee, Haryong Lee
The purpose was to examine the effects of a standard treatment (ST) walking program compared to a ST walking program enhanced (Enhanced Treatment, ET) on cardiovascular health outcomes among Korean-Chinese female migrant workers in Korea. A quasi-experimental sequential design was used. A total of 132 Korean-Chinese women without contraindications to physical activity participated in the study. Both ST and ET groups had monthly goal settings and the ET group received text messages to encourage walking adherence and acculturation...
January 18, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28095107/bioremediation-of-petroleum-wastewater-by-hyper-phenol-tolerant-bacillus-cereus-preliminary-studies-with-laboratory-scale-batch-process
#10
Aditi Banerjee, Aloke K Ghoshal
Petroleum wastewater samples from oil refinery and oil exploration site were treated by hyper phenol-tolerant Bacillus cereus (AKG1 and AKG2) in laboratory-scale batch process to assess their bioremediation efficacy. Quality of the treated wastewater samples were analyzed in terms of removal of chemical oxygen demand (COD), total organic carbon (TOC) and ammonium nitrogen content, and improvement of biological oxygen demand (BOD). Adaptation of these bacteria to the toxic environment through structural changes in their cell membranes was also highlighted...
January 17, 2017: Bioengineered
https://www.readbyqxmd.com/read/28094347/endozoicomonas-genomes-reveal-functional-adaptation-and-plasticity-in-bacterial-strains-symbiotically-associated-with-diverse-marine-hosts
#11
Matthew J Neave, Craig T Michell, Amy Apprill, Christian R Voolstra
Endozoicomonas bacteria are globally distributed and often abundantly associated with diverse marine hosts including reef-building corals, yet their function remains unknown. In this study we generated novel Endozoicomonas genomes from single cells and metagenomes obtained directly from the corals Stylophora pistillata, Pocillopora verrucosa, and Acropora humilis. We then compared these culture-independent genomes to existing genomes of bacterial isolates acquired from a sponge, sea slug, and coral to examine the functional landscape of this enigmatic genus...
January 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28093024/reliability-and-validity-of-the-turkish-version-of-the-rapid-estimate-of-adult-literacy-in-dentistry-treald-30
#12
Kadriye Peker, Taha Emre Köse, Beliz Güray, Ömer Uysal, Tamer Lütfi Erdem
OBJECTIVE: To culturally adapt the Turkish version of Rapid Estimate of Adult Literacy in Dentistry (TREALD-30) for Turkish-speaking adult dental patients and to evaluate its psychometric properties. MATERIAL AND METHODS: After translation and cross-cultural adaptation, TREALD-30 was tested in a sample of 127 adult patients who attended a dental school clinic in Istanbul. Data were collected through clinical examinations and self-completed questionnaires, including TREALD-30, the Oral Health Impact Profile (OHIP), the Rapid Estimate of Adult Literacy in Medicine (REALM), two health literacy screening questions, and socio-behavioral characteristics...
January 16, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28092796/global-open-data-management-in-metabolomics
#13
REVIEW
Kenneth Haug, Reza M Salek, Christoph Steinbeck
Chemical Biology employs chemical synthesis, analytical chemistry and other tools to study biological systems. Recent advances in both molecular biology such as next generation sequencing (NGS) have led to unprecedented insights towards the evolution of organisms' biochemical repertoires. Because of the specific data sharing culture in Genomics, genomes from all kingdoms of life become readily available for further analysis by other researchers. While the genome expresses the potential of an organism to adapt to external influences, the Metabolome presents a molecular phenotype that allows us to asses the external influences under which an organism exists and develops in a dynamic way...
January 13, 2017: Current Opinion in Chemical Biology
https://www.readbyqxmd.com/read/28092422/international-consensus-principles-for-ethical-wildlife-control
#14
Sara Dubois, Nicole Fenwick, Erin A Ryan, Liv Baker, Sandra E Baker, Ngaio J Beausoleil, Scott Carter, Barbara Cartwright, Federico Costa, Chris Draper, John Griffin, Adam Grogan, Gregg Howald, Bidda Jones, Kate E Littin, Amanda T Lombard, David J Mellor, Daniel Ramp, Catherine A Schuppli, David Fraser
Human-wildlife conflicts are commonly addressed by excluding, relocating, or lethally controlling animals with the goal of preserving public health and safety, protecting property, or conserving other valued wildlife. However, declining wildlife populations, a lack of efficacy of control methods in achieving desired outcomes, and changes in how people value animals have triggered widespread acknowledgment of the need for ethical and evidence-based approaches to managing such conflicts. We explored international perspectives on and experiences with human-wildlife conflicts to develop principles for ethical wildlife control...
January 16, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28091847/using-the-newly-developed-floor-sitting-movement-analysis-proforma-to-study-the-effect-of-age-and-activity-on-floor-sitting-in-indian-adults
#15
Anjana Nagrajan, Sebestina A D'Souza
Floor-sitting is culturally relevant to the Indian context. The present study aimed to examine the effect of age and activity on the movement patterns used and time taken to perform floor-sitting in Indian adults. Video-recordings of 30 young (23.30 ± 2.53 years) and 30 older (69.67 ± 6.45 years) adults performing floor-sitting without and with an activity (simulated feeding) were analyzed using the Floor-sitting Movement Analysis Proforma (FMAP) developed for the study. For inter-rater reliability of the FMAP, two raters analyzed the performance of a random sample of 20 participants...
January 16, 2017: Journal of Cross-cultural Gerontology
https://www.readbyqxmd.com/read/28090774/biakamides-a-d-unique-polyketides-from-a-marine-sponge-act-as-selective-growth-inhibitors-of-tumor-cells-adapted-to-nutrient-starvation
#16
Naoyuki Kotoku, Ryosuke Ishida, Hirokazu Matsumoto, Masayoshi Arai, Kazunari Toda, Andi Setiawan, Osamu Muraoka, Motomasa Kobayashi
Biakamides A-D, novel unusually unique polyketides, were isolated from an Indonesian marine sponge (Petrosaspongia sp.) with a constructed bioassay using PANC-1 human pancreatic cancer cells. Through detailed analyses of the one- and two-dimensional nuclear magnetic resonance (NMR) spectra of biakamides, planar chemical structures possessing a terminal thiazole, two N-methyl amides, a chloromethylene, and a substituted butyryl moiety were obtained. After elucidation of the configuration of the secondary alcohol moiety in biakamides A and B, the absolute stereostructures of the two secondary methyl groups in biakamides A-D were determined by the asymmetric total syntheses of all possible stereoisomers from the optically pure monoprotected 2,4-dimethyl-1,5-diol...
January 16, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28089517/hypoxia-induces-a-hif-1-dependent-transition-from-collective-to-amoeboid-dissemination-in-epithelial-cancer-cells
#17
Steffi Lehmann, Veronika Te Boekhorst, Julia Odenthal, Roberta Bianchi, Sjoerd van Helvert, Kristian Ikenberg, Olga Ilina, Szymon Stoma, Jael Xandry, Liying Jiang, Reidar Grenman, Markus Rudin, Peter Friedl
Cancer metastases arise from a multi-step process that requires metastasizing tumor cells to adapt to signaling input from varying tissue environments [1]. As an early metastatic event, cancer cell dissemination occurs through different migration programs, including multicellular, collective, and single-cell mesenchymal or amoeboid migration [2-4]. Migration modes can interconvert based on changes in cell adhesion, cytoskeletal mechanotransduction [5], and/or proteolysis [6], most likely under the control of transcriptional programs such as the epithelial-to-mesenchymal transition (EMT) [7, 8]...
January 11, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28088227/simplified-chinese-version-of-the-forgotten-joint-score-fjs-for-patients-who-underwent-joint-arthroplasty-cross-cultural-adaptation-and-validation
#18
Shiqi Cao, Ning Liu, Wuxiang Han, Yunpeng Zi, Fan Peng, Lexiang Li, Qiwei Fu, Yi Chen, Weijie Zheng, Qirong Qian
BACKGROUND: The Forgotten Joint Score (FJS) is a newly developed health-related quality of life (HRQoL) questionnaire designed to evaluate the awareness after total knee arthroplasty (TKA). This study cross-culturally adapted and psychometrically validated a simplified Chinese version of the FJS (SC-FJS). METHODS: Cross-cultural adaptation was performed according to the internationally recognized guidelines. One-hundred and fifty participants who underwent primary TKA were recruited in this study...
January 14, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28086967/translation-cross-cultural-adaption-and-measurement-properties-of-the-evidence-based-practice-profile
#19
Kristine Berg Titlestad, Anne Kristin Snibsoer, Hilde Stromme, Monica Wammen Nortvedt, Birgitte Graverholt, Birgitte Espehaug
BACKGROUND: The evidence-based practice profile (EBP(2)) questionnaire assesses students' self-reported knowledge, behaviour and attitudes related to evidence-based practice. The aim of this study was to translate and cross-culturally adapt EBP(2) into Norwegian and to evaluate the reliability, validity and responsiveness of the Norwegian version. METHODS: EBP(2) was translated and cross-culturally adapted using recommended methodology. Face validity and feasibility were evaluated in a pilot on bachelor students and health and social workers (n = 18)...
January 13, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28086956/differential-expression-of-e-type-prostanoid-receptors-2-and-4-in-microglia-stimulated-with-lipopolysaccharide
#20
Ester Bonfill-Teixidor, Amaia Otxoa-de-Amezaga, Miriam Font-Nieves, M Glòria Sans-Fons, Anna M Planas
BACKGROUND: Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 (PGE2) is one of the products of COX activity. PGE2 has pleiotropic actions depending on the activation of specific E-type prostanoid EP1-4 receptors. We investigated the involvement of PGE2 and EP receptors in glial activation in response to an inflammatory challenge induced by LPS. METHODS: Cultures of mouse microglia or astroglia cells were treated with LPS in the presence or absence of COX-2 inhibitors, and the production of PGE2 was measured by ELISA...
January 5, 2017: Journal of Neuroinflammation
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