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diagnosis of atopic dermatitis

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https://www.readbyqxmd.com/read/29783251/prevalence-of-risk-factors-of-allergic-diseases-among-children-aged-8-9-years-in-poltava-region-the-results-of-the-first-stage-of-the-research
#1
Tetyana O Kryuchko, Iryna A Holovanova, Olha Y Tkachenko, Mariya O Melnyk, Kateryna V Pocheniuk
OBJECTIVE: Introduction: According to the European Academy of Allergology and Clinical Immunology (EAACI, 2016), allergy is the most common chronic disease in Europe. The aim: The aim of the investigation is to study the spread of risk factors of allergic reactions in children who are 8-9 years old of Poltava region. PATIENTS AND METHODS: Materials and methods: The investigation included two stages: the 1st contained interviewing; the 2nd one - additional clinical and lab investigation of children, who require the further diagnosis specification...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29766369/nutritional-issues-in-food-allergy
#2
REVIEW
Isabel J Skypala, Rebecca McKenzie
Diet and nutrition play an important role in the development and management of food allergy. The diet of expectant mothers can have an effect on their offspring in terms of allergic outcomes. A host of confounding factors may influence this, with a maternal diet rich in fruits and vegetables, fish, vitamin D-rich foods associated with a lower risk of allergic disease in their children. More surprisingly, the consumption of milk and butter has also been shown to have a protective effect, especially in a farm environment...
May 15, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29763349/molar-incisor-hypomineralization-positive-correlation-with-atopic-dermatitis-and-food-allergies
#3
Miguel Hernandez, Juan Boj, Enric Espasa, Paloma Planells, Benjamin Peretz
AIM: Molar-incisor hypomineralization is a disturbance in dental development that involves first permanent molars as well as permanent incisors with a prevalence that ranges from 2.5% to 40%. The objective of this study was to investigate the etiology of molar-incisor hypomineralization among school children from two randomly selected towns in the province of Barcelona, Spain. STUDY DESIGN: A cross-sectional study was conducted with 705 children ranging in age from six years-old to 14 years and 11 months-old...
May 15, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29750772/the-ins-and-outs-of-an-outside-in-view-of-allergies-atopic-dermatitis-and-allergy-prevention
#4
Marcus Shaker, Robert G P Murray, Julianne A Mann
PURPOSE OF REVIEW: The skin barrier is a dynamic innate immune organ. This review summarizes the current understanding of how deficiencies associated with atopic dermatitis invite other atopic disorders of the allergic march. RECENT FINDINGS: Atopic dermatitis is characterized by skin barrier defects (such as mutations in filaggrin), intrinsic proallergic T-helper cell 2 immune dysregulation, and skin microbiome alterations. These factors promote the development of food allergy and asthma...
May 9, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29741524/disseminated-herpes-simplex-virus-a-case-of-eczema-herpeticum-causing-viral-encephalitis
#5
C Finlow, J Thomas
Eczema herpeticum is a dermatological emergency causing a mortality of up to 10% if untreated. It frequently presents in a localised form and rarely disseminates via haematogenous spread with pulmonary, hepatic, ocular and neurological manifestations. Although it commonly appears on a background of atopic dermatitis, many other dermatological conditions have been described preceding this disease. Eczema herpeticum can be easily mistaken for folliculitis and is often treated accordingly with antibacterial drugs; therefore patients will often deteriorate before a diagnosis of eczema herpeticum has been considered...
March 2018: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29725748/atopic-dermatitis-is-a-novel-demographic-risk-factor-for-surgical-site-infection-after-anterior-cruciate-ligament-reconstruction
#6
Manabu Kawata, Yusuke Sasabuchi, Shuji Taketomi, Hiroshi Inui, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Sakae Tanaka
PURPOSE: Although various risk factors for surgical site infection after anterior cruciate ligament reconstruction (ACLR) have been reported, the number of studies with large sample sizes on this topic is limited. The aim of the present study was to clarify the risk factors for early surgical site infection after ACLR in a large cohort using a national database in Japan. METHODS: The data of patients who underwent ACLR from 2010 to 2015 were obtained from the Diagnosis Procedure Combination database, which covers approximately half of all hospital admissions in Japan...
May 3, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29706103/topical-treatment-utilization-for-patients-with-atopic-dermatitis-in-the-united-states-and-budget-impact-analysis-of-crisaborole-ointment-2
#7
Ryan Clark, Duygu Bozkaya, Mark Levenberg, Steven Faulkner, Timothy W Smith, Robert A Gerber
BACKGROUND: Atopic dermatitis (AD), a chronic inflammatory skin disease, is often treated with topical corticosteroids (TCS) and topical calcineurin inhibitors (TCI). Crisaborole ointment is a nonsteroidal, phosphodiesterase 4 inhibitor for the treatment of mild to moderate AD. In December 2016, crisaborole was approved in the US for mild to moderate AD in patients ≥2 years of age. AIMS: To evaluate real-world utilization and cost of TCS and TCI in the US and estimate the budget impact of crisaborole over 2-years from a third-party payer perspective...
April 30, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29706022/terra-firma-forme-dermatosis-is-underestimated-in-children-and-is-associated-with-atopic-dermatitis
#8
I Neri, F Savoia, V Tengattini, A Sechi, P Rucci, A Patrizi
Terra firma-forme dermatosis (TFFD) is an acquired benign disorder that is characterized by brown-gray patches or plaques, presenting as dirt-like pigmented areas (1, 2). The diagnosis is usually confirmed by the clearing with isopropyl or 70% ethyl alcohol swab, that is also the gold standard of treatment. Dermoscopy of TFFD may show large polygonal plate-like brown scales arranged together giving a mosaic or cobblestone pattern (3) This article is protected by copyright. All rights reserved.
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29675643/eyelash-length-for-the-diagnosis-of-atopic-dermatitis-and-ichthyosis-vulgaris-in-children-a-case-control-study
#9
Mehak Singh, Manoj Pawar
Eyelash trichomegaly (ET) is increased length (≥ 12 mm), curling, pigmentation, or thickness of eyelashes. Among acquired causes, allergic diseases and atopic dermatitis (AD) have been found to be associated with eyelash trichomegaly especially in children; however, to date, this claim has not been studied in detail. To compare the eyelash lengths of AD and ichthyosis vulgaris (IV) patients with those of age- and sex-matched patients with unrelated skin disorders, we measured (with a digital Vernier caliper) and compared the eyelash lengths of AD (n = 58) and IV (n = 31) patients to those of age- and sex-matched patients with unrelated skin disorders (n = 178)...
April 19, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29668589/atopic-keratoconjunctivitis-a-diagnostic-dilemma-a-case-report
#10
Aipeng Li, Shang Li, Fang Ruan, Ying Jie
RATIONALE: Atopic keratoconjunctivitis (AKC) remains a difficult diagnosis despite advances in imaging technologies. This is a case study of the diagnostic and treatment course for a patient with AKC. PATIENT CONCERNS: A 15-year-old male complained of progressively increasing pain, redness, watering and blurred vision in the right eye. The medical history showed that the patient suffered from itching on the hands, knees, neck and the eye skin one year before the onset of initial symptoms in the affected eye...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29645380/s1-guidelines-dermatoses-associated-with-dermal-lymphostasis
#11
Joachim Dissemond, Finja Jockenhöfer, Anya Miller, Günter Kurzhals, Shahrouz Noori, Stefanie Reich-Schupke, Martin Schlaeger, Erich Schubert, Markus Stücker, Tobias Weberschock, Hans Wilfried Jungkunz
The objective of the present S1 guidelines is to present current knowledge about dermatologically relevant diseases associated with localized dermal lymphostasis, thus facilitating their early detection, diagnostic workup, and targeted treatment. Whenever possible, treatment should be based on stage-appropriate and clearly defined algorithms. The numerous issues regarding differential diagnosis and treatment clinicians are confronted with in everyday clinical practice seem to warrant the publication of up-to-date guidelines...
April 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29642409/squamous-cell-carcinoma-antigen-2-scca2-serpinb4-an-emerging-biomarker-for-skin-inflammatory-diseases
#12
REVIEW
Kenji Izuhara, Yukie Yamaguchi, Shoichiro Ohta, Satoshi Nunomura, Yasuhiro Nanri, Yoshinori Azuma, Noriko Nomura, Yasuhiko Noguchi, Michiko Aihara
Squamous cell carcinoma antigens 1 and 2 (SCCA1 and 2, SERPIN B3 and B4), members of the ovalbumin serpin (ov-serpin)/clade B serpin family, were originally discovered as tumor-specific antigens and are used as tumor markers for various kinds of squamous cell carcinomas. Recently, our understanding of the underlying mechanisms of how SCCA1/2 enhance tumor growth has greatly increased. Moreover, it has been shown that SCCA1/2 are involved in the pathogenesis of several inflammatory diseases: asthma, psoriasis, and atopic dermatitis (AD)...
April 6, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29630150/a-possible-role-for-dupilumab-dupixent-in-the-management-of-idiopathic-chronic-eczematous-eruption-of-aging
#13
Grace C Brummer, Lawrence T Wang, Richard D Sontheimer
Aging individuals can develop generalized, exquisitely-pruritic, eczematous eruptions of uncertain etiology that can be therapeutically-refractory and life-altering. Limited information exists in the literature to guide clinicians in the diagnosis and management of such patients. It is suggested that in approximately 40% of such patients a known cause for their chronic pruritic eruptions cannot be identified. In this report we will refer to this subgroup of patients as having idiopathic chronic eczematous eruption of aging (CEEA)...
February 15, 2018: Dermatology Online Journal
https://www.readbyqxmd.com/read/29559151/established-and-novel-approaches-for-teaching-and-learning-of-veterinary-parasitology-in-berlin
#14
Peter-Henning Clausen, Sandra Stelzer, Ard Nijhof, Jürgen Krücken, Georg von Samson-Himmelstjerna
The teaching of veterinary parasitology to the large number of students at the Freie Universität Berlin is mainly limited to conventional face-to-face lectures, supplemented by practical classes. Extensive parasite descriptions and diagnostic techniques are at the core of the practical classes, which are also intended to emphasise key biological and veterinary aspects covered in lectures. Further in-depth and specific learning is achieved within a detailed framework of elective courses, with defined learning outcomes for small groups of students, focusing on themes such as 'diagnosis and treatment of ectoparasites in companion animals' or 'zoonotic parasites'...
March 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29555105/assessment-of-il-31-levels-and-disease-severity-in-children-with-atopic-dermatitis
#15
D Ozceker, M Bulut, A Celik Ozbay, F Dilek, M Koser, Z Tamay, N Guler
INTRODUCTION AND OBJECTIVES: Atopic dermatitis is a chronic, relapsing, highly pruritic, inflammatory skin disease characterized by typical localization with increasing prevalence of 10-20% in children. Pruritus is one of the major diagnostic criteria of atopic dermatitis and also the main complaint altering quality-of-life of affected patients, inducing and aggravating inflammation. Although pruritus is the absolute symptom of AD, the etiology has not been fully explained yet and current antihistamine therapies are ineffective...
March 16, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29552874/allergic-conjunctivitis-current-concepts-on-pathogenesis-and-management
#16
M Sacchetti, I Abicca, A Bruscolini, C Cavaliere, M Nebbioso, A Lambiase
Allergic conjunctivitis (AC) includes a wide spectrum of clinical entities characterized by different incidence, age of onset, natural course, clinical outcome and response to treatment. Taken together, they represent one of the most frequent ocular surface diseases affecting more than 30% of the young-adult population and show an increasing incidence over the years. Moreover, comorbidities with other systemic atopic conditions such as asthma, atopic dermatitis and rhinitis require a multidisciplinary approach...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29536938/not-all-that-vesicles-is-herpes
#17
Robert R Gruhl, Andrew Wu, Micah Niermann, Andrew Olson
BACKGROUND: Eczema coxsackium (EC) can manifest in patients with underlying atopic dermatitis (AD) as a diffuse vesicular rash in a febrile child. The presentation overlaps clinically with the feared diagnosis of eczema herpeticum (EH), which makes differentiating between the conditions very important. CASE PRESENTATION: A 6-month-old girl with known AD presented with fever and rapidly spreading vesicular rash. The patient had multiple exposures including a new antibiotic prescription, introduction of new foods, 6-month vaccinations and a sick contact...
November 27, 2017: Diagnosis
https://www.readbyqxmd.com/read/29527381/an-8-year-old-child-with-delayed-diagnosis-of-netherton-syndrome
#18
Alexander K C Leung, Benjamin Barankin, Kin Fon Leong
We report an 8-year-old boy with Netherton syndrome who was misdiagnosed and treated as severe atopic dermatitis. The diagnosis of Netherton syndrome was not made until the child was 8 years of age. We discuss the pitfalls in the diagnosis and alert physicians to the proper and early diagnosis of this syndrome. The child was treated with a low dose (0.25 mg/kg) of oral acitretin and a topical moisturizer with marked improvement of his skin and pruritus in 2 months. At 6-month follow-up, the skin was almost clear of erythema and scaling, and the hair was longer and stronger...
2018: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29499796/evaluating-and-optimizing-the-diagnosis-of-erythematotelangiectatic-rosacea
#19
REVIEW
Mohammed D Saleem, Jonathan K Wilkin
Erythematotelangiectatic rosacea is the most prevalent rosacea subtype. Multiple dermatologic conditions may mimic erythematotelangiectatic rosacea. The authors review a comprehensive approach to evaluating subjects with a suspected diagnosis of erythematotelangiectatic rosacea and discuss findings that may warrant further investigation. Differential diagnoses can be narrowed based on the presence of characteristics such as transient erythema, nontransient erythema, and telangiectasias. A thorough history and physical examination are critical in ruling out conditions such as dermatomyositis, lupus erythematosus, atopic dermatitis, and seborrheic dermatitis...
April 2018: Dermatologic Clinics
https://www.readbyqxmd.com/read/29498135/a-preliminary-study-of-serum-ige-against-cross-reactive-carbohydrate-determinants-ccd-in-client-owned-atopic-dogs
#20
Britt J Levy, Douglas J DeBoer
BACKGROUND: Cross-reactive carbohydrate determinants (CCD) are defined carbohydrate portions of glycoprotein cell surface molecules common to many plant and insect species. Mammalian species recognize CCD as foreign antigens and can mount humoral immune responses against them. Approximately 20-37% of grass and venom allergic people possess circulating IgE against CCD; these antibodies are generally considered clinically irrelevant. Anti-CCD IgE is, however, recognized as a cause of false positive, clinically incongruent serum allergen test results in people; this phenomenon has not been investigated in animals...
March 1, 2018: Veterinary Dermatology
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