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diagnosis of atopic dermatitis

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https://www.readbyqxmd.com/read/28904961/analysis-of-epidemiology-and-risk-factors-of-atopic-dermatitis-in-korean-children-and-adolescents-from-the-2010-korean-national-health-and-nutrition-examination-survey
#1
Kyung Suk Lee, In-Hwan Oh, Sun Hee Choi, Yeong-Ho Rha
BACKGROUND: Atopic dermatitis (AD) is a common chronic inflammatory skin disease, but only few studies involved samples of children and adolescents that are representative of the entire Korean population. This study aimed to estimate the prevalence and risk factors of AD among children and adolescents in Korea by using nationally representative data. METHODS: We used data from the fifth Korean National Health and Nutrition Examination Survey in 2010 and retrospectively evaluated 2,116 children and adolescents...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28901591/evaluation-of-the-correlation-between-scoring-feline-allergic-dermatitis-and-feline-extent-and-severity-index-and-skin-hydration-in-atopic-cats
#2
Marcin P Szczepanik, Piotr M Wilkołek, Łukasz R Adamek, Marcin Zając, Marcin Gołyński, Wiesław Sitkowski, Iwona Taszkun
BACKGROUND: Evaluation of the severity of clinical signs of cats with allergic skin diseases has used two scoring systems: Scoring Feline Allergic Dermatitis (SCORFAD) and the Feline Extent and Severity Index (FeDESI). The integrity of the cutaneous barrier can also be evaluated by measuring skin hydration. A correlation between the clinical score and skin hydration has been observed in humans and dogs with atopic dermatitis (AD). HYPOTHESIS: To demonstrate a correlation between the clinical score and skin hydration of cats affected with presumed AD...
September 13, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28895954/diagnosis-comorbidity-and-psychosocial-impact-of-atopic-dermatitis
#3
Dawn Marie Davis, Andrea Waldman, Sharon Jacob, Jennifer LeBovidge, Jusleen Ahluwalia, Megha Tollefson, Nathan Jetter, Jonathan Spergel
Atopic dermatitis (AD) is a chronic inflammatory skin disease, with a remitting relapsing course. The central diagnostic features of AD include pruritus, xerosis, eczematous lesions with a characteristic morphology and distribution, and a personal or family history of atopic disease. Several clinical studies have emphasized the link between AD and other atopic disorders including asthma, allergic rhinitis, and food allergies. More recent studies indicate possible links between AD and other nonatopic disorders, including ADHD, sleep disturbance, and mental health disorders, suggesting an even more profound impact of this disease...
September 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28895698/serum-prolactin-levels-in-atopic-dermatitis-and-the-relationship-with-disease-severity
#4
Burcu Tugrul Ayanoğlu, Özgül Muştu Koryürek, Songül Yıldırm Başkara
BACKGROUND: Prolactin performs as a neuroendocrine modulator of skin epithelial cell proliferation and the skin immune system. OBJETIVE: The aim was to assess the serum prolactin levels in patients with atopic dermatitis and the relationship with disease severity. METHODS: The study was performed on 46 patients with atopic dermatitis and 100 healthy controls aged between 0.5 years and 19.5 years. The diagnosis of atopic dermatitis was based on clinical findings and the severity of the disease was documented...
October 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28893022/correlation-of-vitamin-d3-levels-and-scorad-index-in-atopic-dermatits-a-case-control-study
#5
Saurabh Sharma, Tejinder Kaur, Suresh Kumar Malhotra, Jaswant Rai, Sunil Chaudhari
INTRODUCTION: Atopic Dermatitis (AD) is a common chronic inflammatory condition characterized clinically by pruritus and eczematous lesions. An inverse relationship has been suggested between serum 25-hydroxyvitamin D concentration and severity of atopic dermatitis. AIM: We carried out this controlled cross-sectional study to evaluate the association between the serum vitamin D3 levels and SCORAD index. MATERIALS AND METHODS: For this study, 40 patients with clinical diagnosis of AD based on UK diagnostic criteria were enrolled and 40 patients with minor ailments like superficial bacterial, fungal or viral infections and not suffering from atopic dermatitis were taken as controls...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28842320/skin-colonization-by-staphylococcus-aureus-precedes-the-clinical-diagnosis-of-atopic-dermatitis-in-infancy
#6
P Meylan, C Lang, S Mermoud, A Johannsen, S Norrenberg, D Hohl, Y Vial, G Prod'hom, G Greub, M Kypriotou, S Christen-Zaech
Atopic dermatitis (AD) has a well-established association with skin colonization or infection by Staphylococcus aureus, which can exacerbate the disease. However, a causal relationship between specific changes in skin colonization during the first years of life and AD development still remains unclear. In this prospective birth cohort study, we aimed to characterize the association between skin colonization and AD development in 149 Caucasian infants with or without a family history of atopy. We assessed infants clinically and collected axillary and antecubital fossa skin swabs for culture-based analysis, at birth and at seven time points over the first two years of life...
August 22, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28838840/-hand-eczema-in-children-clinical-and-epidemiological-study-of-the-population-referred-to-a-tertiary-hospital
#7
José María Ortiz-Salvador, Daniela Subiabre-Ferrer, Ana García Rabasco, Altea Esteve-Martínez, Violeta Zaragoza-Ninet, Víctor Alegre de Miquel
INTRODUCTION: Hand eczema is a frequent disease in adults. Diagnosing the cause of hand eczema is difficult due to different classifications. There is lack of evidence on hand eczema and its causes in children. MATERIAL AND METHOD: A total of 389 children between 0 and 16 years were identified between 1996 and 2016, from whom 42 (10.8%) with exclusively hand eczema were selected. In all cases a standard battery of epicutaneous patch tests was performed, as well as additional batteries depending on the clinical suspicion...
August 21, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28799561/retinal-detachment-repair-and-cataract-surgery-in-patients-with-atopic-dermatitis
#8
V Gnana Jothi, S McGimpsey, J A Sharkey, W C Chan
PurposeThe aim of this study is to report a case series of ocular complications including retinal detachment (RD) and cataract in atopic dermatitis (AD) and surgical management involving a majority of Caucasian patients.Patients and methodsThis study is an observational case series, originally designed as an audit. It involves detailed discussion of history, clinical features, and surgical management of patients presenting with retinal detachment and cataracts secondary to severe AD. Six consecutive patients with diagnosis of severe AD requiring posterior segment and cataract surgery were included in the study...
September 2017: Eye
https://www.readbyqxmd.com/read/28789575/prescriptions-for-atopic-dermatitis-oral-corticosteroids-remain-commonplace
#9
Tiffany Alexander, Elena Maxim, Leah A Cardwell, Aneesh Chawla, Steven R Feldman
INTRODUCTION: Atopic dermatitis (AD) is a common, chronic inflammatory skin disease characterized by pruritic, often lichenified, patches and plaques. METHODS: Data were obtained from the Humana database, a large claims-based database encompassing more than 20 million patients under a commercial healthcare insurance plan. Our cohort included 39,526 subjects who saw a dermatologist for a primary ICD-9 diagnosis of atopic dermatitis (691.8) between the years of 2010-2015...
August 9, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28735503/association-between-allergic-disease-sleep-disordered-breathing-and-childhood-nocturnal-enuresis-a-population-based-case-control-study
#10
Jeng-Dau Tsai, Hsuan-Ju Chen, Min-Sho Ku, Shan-Ming Chen, Chih-Chuan Hsu, Min-Che Tung, Che-Chen Lin, Hsing-Yi Chang, Ji-Nan Sheu
BACKGROUND: Little is known about the associations between allergic disease, sleep-disordered breathing (SDB), and childhood nocturnal enuresis (NE). We examined whether allergic disease and SDB were associated with childhood NE. METHODS: Data were assessed from the 2007-2012 Taiwan National Health Insurance Research Database. We enrolled 4308 children aged 5-18 years having NE diagnosis and age- and sex-matched 4308 children as the control group. The odds ratios of NE were calculated to determine an association with preexisting allergic disease and SDB...
July 22, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28730653/dermatitis-of-the-foot-epidemiologic-and-clinical-features-in-389-children
#11
José-María Ortiz-Salvador, Altea Esteve-Martínez, Ana García-Rabasco, Daniela Subiabre-Ferrer, Lorena Martínez-Leboráns, Violeta Zaragoza-Ninet
BACKGROUND/OBJECTIVES: Footwear dermatitis is a form of contact dermatitis resulting from exposure to shoes. There have been only small studies regarding foot contact dermatitis in children. The present study was undertaken to define the prevalence and epidemiologic and clinical features of shoe dermatitis in children. METHODS: A retrospective study was undertaken of all children referred for patch testing between 1996 and 2015. Children with dermatitis limited to the feet were selected...
July 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28703865/identification-of-unique-proteomic-signatures-in-allergic-and-non-allergic-skin-disease
#12
Jingya Wang, Mayte Suárez-Fariñas, Yeriel Estrada, Melissa L Parker, Lydia Greenlees, Geoffrey Stephens, James Krueger, Emma Guttman-Yassky, Michael D Howell
BACKGROUND: Atopic dermatitis (AD), psoriasis (PS), and contact dermatitis (CD) are common skin diseases, characterized by barrier disruption and systemic inflammation, with unique epidermal signatures and common inflammatory pathways identified by transcriptomic profiling. This study profiled proteomic signatures in serum from subjects with AD, PS, and CD compared with healthy controls (HC). OBJECTIVE: Identify unique proteomic signatures to distinguish between inflammatory diseases with similar epidermal disruption and overlapping epithelial inflammation...
July 13, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28697160/severe-infant-rash-resistant-to-therapy-due-to-zinc-deficiency-a-case-report
#13
Javed Mohammed, Shruti Mehrotra, Helene Schulz, Rodrick Lim
Pediatric skin diseases are a common presenting complaint to emergency medicine physicians but often pose a significant diagnostic challenge. Skin eruptions that are unusually severe for the diagnosis in question, lasting beyond the typical time of resolution, or not responding to conventional therapy should raise concern of a misdiagnosis. We present the case of a severe rash not responding to conventional atopic dermatitis therapy that led to a diagnosis of transient neonatal zinc deficiency. Clinicians caring for children should be aware of zinc deficiency and its corresponding clinical presentation, because it is readily treatable and may lead to the avoidance of unnecessary treatments and prevention of serious complications...
July 11, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28695412/-basis-for-the-treatment-of-eczematous-diseases-in-otorhinolaryngology
#14
REVIEW
R Fölster-Holst, A Sperl, T Albrecht, L Klimek
According to Coombs and Gell, cell-mediated immune responses belong to type IV reactions and are borne mainly by T lymphocytes. The eliciting allergens are usually so-called haptens. Haptens are substances which develop to whole antigens only by binding to protein carriers. In otorhinolaryngology, delayed allergic hypersensitivities are apparent mainly as contact eczemata. Facial dermatitis, auricle and ear canal eczema as well as perioral eczema belong to the most common forms of contact dermatitis in ENT patients...
July 10, 2017: HNO
https://www.readbyqxmd.com/read/28681396/association-of-atopy-and-tentative-diagnosis-of-skin-cancer-results-from-occupational-skin-cancer-screenings
#15
I Schäfer, P Mohr, N Zander, R Fölster-Holst, M Augustin
BACKGROUND: The relationship between atopic conditions and carcinoma of the skin has been described inconsistently. Population-based data providing information on atopic diseases as well as on skin cancer are sparse. OBJECTIVE: To determine the correlation between atopy and prevalence of precanceroses, non-melanoma skin cancer and malignant melanoma (MM), while taking into account known risk factors for skin cancer. METHODS: Data from occupational skin cancer screenings were analysed in a cross-sectional study...
July 6, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28677360/a-metagenomic-analysis-provides-a-culture-independent-pathogen-detection-for-atopic-dermatitis
#16
Min Hye Kim, Mina Rho, Jun Pyo Choi, Hyun Il Choi, Han Ki Park, Woo Jung Song, Taek Ki Min, Sang Heon Cho, Young Joo Cho, Yoon Keun Kim, Sanghwa Yang, Bok Yang Pyun
PURPOSE: Atopic dermatitis (AD) is an inflammatory skin disease, significantly affecting the quality of life. Using AD as a model system, we tested a successive identification of AD-associated microbes, followed by a culture-independent serum detection of the identified microbe. METHODS: A total of 43 genomic DNA preparations from washing fluid of the cubital fossa of 6 healthy controls, skin lesions of 27 AD patients, 10 of which later received treatment (post-treatment), were subjected to high-throughput pyrosequencing on a Roche 454 GS-FLX platform...
September 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28677237/superiority-of-a-vitamin-b12-barrier-cream-compared-with-standard-glycerol-petrolatum-based-emollient-cream-in-the-treatment-of-atopic-dermatitis-a-randomized-left-to-right-comparative-trial
#17
S P Nistico, E Del Duca, F Tamburi, E Pignataro, N De Carvalho, F Farnetani, G Pellacani
Atopic dermatitis (AD) is a result of complex genetic, epigenetic, environmental, and immunological interactions with an overlapping epidermal barrier defect. The study evaluates the efficacy and tolerability of topical Vitamin B12-barrier cream (MB12) compared with standard glycerol-petrolatum-based emollient cream (GPC) used three times a day for mild AD. The study was conducted as a on one hemi-body randomized, controlled, single-blind, intra-patient left-to-right comparative trial by patients with clinical diagnosis of mild AD measured with total SCORAD index over 4 months...
July 4, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28676880/innovations-and-developments-in-dermatologic-non-invasive-optical-imaging-and-potential-clinical-applications
#18
Eric Tkaczyk
Most dermatologists are aware of the benefits of dermoscopy, and a few are familiar with laser-scanning confocal microscopy. Beyond confocal, there are fully 11 different categories of optical techniques that have been applied to clinical dermatology. This article first provides a comprehensive tabular overview of all these optical diagnostic technologies and then details 4 of the lesser known innovations that are already available or still in development (laser Doppler and speckle imaging, Raman spectroscopy, multiphoton microscopy, photoacoustic tomography), with some potential applications in clinical dermatology (blood flow monitoring, skin cancer diagnosis, composition measurements in atopic dermatitis, skin rejuvenation measurement, and noninvasive sentinel lymph node assessment in melanoma)...
July 5, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28668110/association-of-maternal-depression-and-allergic-diseases-in-korean-children
#19
Cheol Hong Kim, Sung Hoon Kim, Ju Suk Lee
PURPOSE: An association between childhood allergic disease and parental psychological disorders has been reported. However, little is known about the relationship between childhood allergic disease and maternal depression. This study was performed to determine if there is an association between childhood allergic disease and maternal depression. METHODS: Data were acquired from 13,782 subjects (8091 mothers) ages < 18 years who participated in the Korea National Health and Nutrition Examination Surveys, which was conducted from 2007 to 2014...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28654708/practical-strategies-for-the-diagnosis-and-assessment-of-atopic-dermatitis
#20
REVIEW
Lawrence F Eichenfield, Linda F Stein Gold
Atopic dermatitis (AD) has a significant, lifelong clinical impact on affected individuals and has profound effects on quality of life both for patients and their families. The diagnosis usually can be reliably established on the basis of the history and physical examination. In patients with skin of color, blanching of the skin may be helpful to detect erythema, lichenification, follicular accentuation, and hypopigmentation (all of which are more common than in lighter-skinned patients). Once the diagnosis of AD is established, an assessment of severity, persistence, and impact on the patient's and family's life is important as a guide to treatment decisions...
March 2017: Seminars in Cutaneous Medicine and Surgery
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