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chronic pain physiopatology

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https://www.readbyqxmd.com/read/19780420/-quality-of-life-assessment-in-patients-with-multiple-sclerosis
#1
Darija Kisić Tepavcević, Tatjana Pekmezović, Jelena Drulović
BACKGROUND/AIM: Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. The main physiopatological feature of MS is demyelination. Multiple sclerosis is one of three most common causes of severe disability in youngest people. In patients with MS, apart from complete psychophysical status and objective neurologic status, a subjective perception of symptoms and signs, known as quality of life, must be considered, too. The aim of this study was to estimate a health related quality of life (HRQoL) in patients with multiple sclerosis (MS) and to investigate the correlations between scores of HRQoL and selected demographic and clinical parameters...
August 2009: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/16047719/usefulness-of-montelukast-to-prevent-adverse-reactions-to-cox-2-selective-inhibitors-a-case-report
#2
C Serrano, A Valero, C Picado
Nonsteroidal anti-inflammatory drug (NSAID)-sensitivity is a frequent condition in patients with chronic urticaria and/or asthma. The physiopatologic process underlying respiratory and cutaneous reactions probably involves an increased production of cysteinyl leukotrienes. Cyclooxygenase 2 (COX-2) selective inhibitor, has been proposed as the main alternative to control pain and inflammatory diseases in these patients. However, a small percentage of patients with NSAID-induced skin reactions does not even tolerate COX-2 selective inhibitors...
2005: Journal of Investigational Allergology & Clinical Immunology
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