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https://www.readbyqxmd.com/read/29036217/-abc-the-awareness-body-chart-a-new-tool-assessing-body-awareness
#1
Ursula Danner, Alexander Avian, Tanja Macheiner, Beate Salchinger, Nina Dalkner, Frederike T Fellendorf, Armin Birner, Susanne A Bengesser, Martina Platzer, Hans-Peter Kapfhammer, Michel Probst, Eva Z Reininghaus
BACKGROUND: Despite the importance of body awareness for health and well-being there is still a lack of valid assessment tools to scan proper body awareness. To respond to the limitations of questionnaires (reading/interpretation problems) the Awareness-Body-Chart (ABC) was designed to assess body awareness by colouring 51 regions according to their awareness. The objective of this study was to investigate the psychometric characteristics of the ABC. METHODS: In a questionnaire-study, 106 students in Graz (79 females, 27 males, age median 21 (IQR 20-23) years) filled in the ABC, furthermore a German body awareness questionnaire "KEKS", and the Beck Depression Inventory II...
2017: PloS One
https://www.readbyqxmd.com/read/29032287/adaptation-of-the-mabc-2-test-age-band-2-for-children-with-low-vision
#2
Hanne Alves Bakke, Silvia Wanick Sarinho, Maria Teresa Cattuzzo
BACKGROUND: The tools used to assess motor performance in children with low vision often have no validity and reliability data concerning this population and use non-standardized modifications. Adaptations of these tools could help to identify motor problems and mitigate their effects. AIM: To assess aspects of validity and reliability in an adaptation of the Movement ABC-2 Test (MABC-2) for children with low vision. METHODS AND PROCEDURES: The research was undertaken in two stages: 1) application of the original MABC-2 to 10 children with low vision, adaptation and pilot test; 2) administration and re-administration of the adapted MABC-2 in 30 children with low vision...
October 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29027815/l-carnosine-as-an-adjunctive-therapy-to-risperidone-in-children-with-autistic-disorder-a-randomized-double-blind-placebo-controlled-trial
#3
Reihaneh Hajizadeh-Zaker, Alireza Ghajar, Bita Mesgarpour, Mohsen Afarideh, Mohammad-Reza Mohammadi, Shahin Akhondzadeh
OBJECTIVES: This study aimed at investigating the efficacy and tolerability of l-carnosine as an add-on to risperidone in the management of children with autism. METHODS: This was a 10-week, randomized, double-blind, placebo-controlled study. Seventy drug-free children aged 4-12 years old with a diagnosis of autism spectrum disorder (ASD), according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition. (DSM-5) who had an Aberrant Behavior Checklist-Community (ABC-C) scale irritability subscale score of ≥12, entered the study...
October 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29025170/-the-motor-development-of-children-with-infantile-esotropia
#4
Julia Dillmann, Claudia Freitag, Kerstin Holve, Silke Schweinfurth, Birgit Lorenz, Gudrun Schwarzer
Background Until now, many studies have investigated the link between motor development and visual-spatial abilities in infancy and childhood. Most of these studies found evidence that there is such a link in typically developing children or children with locomotor delay. Only a few studies have tested the consequences of this link in children with abnormal visual development because of infantile esotropia. Moreover, little is known about the effects of late surgery on motor development. Patients and Methods We assessed the motor abilities of 3- to 7-year old children with severe deficits in stereopsis due to infantile esotropia (angle ≥ 12°) and typically developing children prior to and 12 to 16 months after surgery...
October 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29020355/effects-of-empagliflozin-on-risk-for-cardiovascular-death-and-heart-failure-hospitalization-across-the-spectrum-of-heart-failure-risk-in-the-empa-reg-outcome%C3%A2-trial
#5
David Fitchett, Javed Butler, Philippe van de Borne, Bernard Zinman, John M Lachin, Christoph Wanner, Hans J Woerle, Stefan Hantel, Jyothis T George, Odd Erik Johansen, Silvio E Inzucchi
Aims: Empagliflozin reduced the risk of cardiovascular (CV) death and heart failure (HF) hospitalizations in patients with type 2 diabetes (T2D) and established CV disease (CVD) in the EMPA-REG OUTCOME® trial. We investigated whether the benefit of empagliflozin was observed across the spectrum of HF risk. Methods and results: Seven thousand and twenty patients with T2D (HbA1c 7-10% and eGFR > 30 mL/min/1.73 m2) were treated with empagliflozin 10 or 25 mg, or placebo once daily and followed for median 3...
August 28, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29017765/accuracy-of-shock-index-versus-abc-score-to-predict-need-for-massive-transfusion-in-trauma-patients
#6
Rebecca Schroll, David Swift, Danielle Tatum, Stuart Couch, Jiselle B Heaney, Monica Llado-Farrulla, Shana Zucker, Frances Gill, Griffin Brown, Nicholas Buffin, Juan Duchesne
BACKGROUND: Various scoring systems have been developed to predict need for massive transfusion in traumatically injured patients. Assessments of Blood Consumption (ABC) score and Shock Index (SI) have been shown to be reliable predictors for Massive Transfusion Protocol (MTP) activation. However, no study has directly compared these two scoring systems to determine which is a better predictor for MTP activation. The primary objective was to determine whether ABC or SI better predicted the need for MTP in adult trauma patients with severe hemorrhage...
September 15, 2017: Injury
https://www.readbyqxmd.com/read/29017727/effects-of-low-level-prenatal-exposure-to-dioxins-on-cognitive-development-in-japanese-children-at-42months
#7
Tamiko Ikeno, Chihiro Miyashita, Sonomi Nakajima, Sumitaka Kobayashi, Keiko Yamazaki, Yasuaki Saijo, Toshiko Kita, Seiko Sasaki, Kanae Konishi, Junboku Kajiwara, Tsuguhide Hori, Reiko Kishi
BACKGROUND: Prenatal exposure to polychlorinated dibenzo-p-dioxins (PCDDs) or polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dioxin-like compounds [DLCs]) through environmental chemicals may affect the neurodevelopment of children. In our previous study, an inverse association was observed between prenatal DLCs and neurodevelopment of infants aged 6months in both sexes. However, studies are yet to determine how long these adverse effects last. OBJECTIVE: To examine whether the effects of DLCs on cognitive development remains at 42months...
October 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28991676/sulfonylurea-drug-pretreatment-and-functional-outcome-in-diabetic-patients-with-acute-intracerebral-hemorrhage
#8
Jason J Chang, Yasser Khorchid, Ali Kerro, L Goodwin Burgess, Nitin Goyal, Anne W Alexandrov, Andrei V Alexandrov, Georgios Tsivgoulis
PURPOSE: Intracerebral hemorrhage (ICH) is associated with poor clinical outcome and high mortality. Sulfonylurea (SFU) use may be a viable therapy for inhibiting sulfonylurea receptor-1 and NCCa-ATP channels and reducing perihematomal edema and blood-brain barrier disruption. We sought to evaluate the effects of prehospital SFU use with outcomes in diabetic patients with acute ICH. METHODS: We retrospectively analyzed a cohort of diabetic patients presenting with acute ICH at a tertiary care center...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28977197/collaborative-quality-improvement-in-the-congenital-heart-defects-development-of-the-assist-consortium-and-a-preliminary-surgical-outcomes-report
#9
Fabio Carmona, Paulo Henrique Manso, Mariana Nicoletti Ferreira, Nana Miura Ikari, Marcelo Biscegli Jatene, Luciana Amato, Aida Luiza Turquetto, Luiz Fernando Caneo
OBJECTIVE: ASSIST is the first Brazilian initiative in building a collaborative quality improvement program in pediatric cardiology and congenital heart disease. The purposes of this manuscript are: (a) to describe the development of the ASSIST project, including the historical, philosophical, organizational, and infrastructural components that will facilitate collaborative quality improvement in congenital heart disease care; (b) to report past and ongoing challenges faced; and (c) to report the first preliminary data analysis...
July 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28958324/physical-activity-and-mortality-in-patients-with-stable-coronary-heart-disease
#10
RANDOMIZED CONTROLLED TRIAL
Ralph A H Stewart, Claes Held, Nermin Hadziosmanovic, Paul W Armstrong, Christopher P Cannon, Christopher B Granger, Emil Hagström, Judith S Hochman, Wolfgang Koenig, Eva Lonn, José C Nicolau, Philippe Gabriel Steg, Ola Vedin, Lars Wallentin, Harvey D White
BACKGROUND: Recommendations for physical activity in patients with stable coronary heart disease (CHD) are based on modest evidence. OBJECTIVES: The authors analyzed the association between self-reported exercise and mortality in patients with stable CHD. METHODS: A total of 15,486 patients from 39 countries with stable CHD who participated in the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) study completed questions at baseline on hours spent each week taking mild, moderate, and vigorous exercise...
October 3, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28938872/effect-of-vitamin-a-supplementation-on-gut-microbiota-in-children-with-autism-spectrum-disorders-a-pilot-study
#11
Juan Liu, Xiao Liu, Xue-Qin Xiong, Ting Yang, Ting Cui, Na-Li Hou, Xi Lai, Shu Liu, Min Guo, Xiao-Hua Liang, Qian Cheng, Jie Chen, Ting-Yu Li
BACKGROUND: Dysbiosis of gut microbiota are commonly reported in autism spectrum disorder (ASD) and may contribute to behavioral impairment. Vitamin A (VA) plays a role in regulation of gut microbiota. This study was performed to investigate the role of VA in the changes of gut microbiota and changes of autism functions in children with ASD. RESULTS: Sixty four, aged 1 to 8 years old children with ASD completed a 6-month follow-up study with VA intervention. High-performance liquid chromatography was used to assess plasma retinol levels...
September 22, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28927344/structural-elucidation-of-transmembrane-domain-zero-tmd0-of-ecdl-a-multidrug-resistance-associated-protein-mrp-family-of-atp-binding-cassette-transporter-protein-revealed-by-atomistic-simulation
#12
Krishnendu Bera, Priyanka Rani, Gaurav Kishor, Shikha Agarwal, Antresh Kumar, Durg Vijay Singh
ATP-Binding cassette (ABC) transporters play an extensive role in the translocation of diverse sets of biologically important molecules across membrane. EchnocandinB (antifungal) and EcdL protein of Aspergillus rugulosus are encoded by the same cluster of genes. Co-expression of EcdL and echinocandinB reflects tightly linked biological functions. EcdL belongs to Multidrug Resistance associated Protein (MRP) subfamily of ABC transporters with an extra transmembrane domain zero (TMD0). Complete structure of MRP subfamily comprising of TMD0 domain, at atomic resolution is not known...
September 20, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28922315/validation-of-fear-of-falling-and-balance-confidence-assessment-scales-in-persons-with-dystonia
#13
M J Boyce, L Lam, F Chang, N Mahant, V S C Fung, L Bradnam
BACKGROUND AND PURPOSE: Falls are problematic for people living with neurological disorders and a fear of falling can impact on actual falls. Fear of falling is commonly assessed using the Falls Self-Efficacy Scale International (FES-I) or the Activities-specific Balance Confidence (ABC) Scale. These scales can predict risk of falling. We aimed to validate the FES-I and the ABC in persons with dystonia. METHODS: We conducted an online survey of people with dystonia, collecting information on demographics, 6-month falls history, dystonia disability, and the FES-I and ABC scales...
October 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28919764/levetiracetam-is-associated-with-decrease-in-subclinical-epileptiform-discharges-and-improved-cognitive-functions-in-pediatric-patients-with-autism-spectrum-disorder
#14
Minjian Wang, Li Jiang, Xiaoju Tang
OBJECTIVE: Subclinical epileptiform discharges (SEDs) are common in pediatric patients with autism spectrum disorder (ASD), but the effect of antiepileptic drugs on SEDs in ASD remains inconclusive. This physician-blinded, prospective, randomized controlled trial investigated an association between the anticonvulsant drug levetiracetam and SEDs in children with ASD. METHODS: A total of 70 children with ASD (4-6 years) and SEDs identified by electroencephalogram were randomly divided into two equal groups to receive either levetiracetam and educational training (treatment group) or educational training only (control)...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28906207/high-absolute-basophil-count-is-a-powerful-independent-predictor-of-inferior-overall-survival-in-patients-with-primary-myelofibrosis
#15
Marko Lucijanic, Ana Livun, Tajana Stoos-Veic, Vlatko Pejsa, Ozren Jaksic, David Cicic, Jelena Lucijanic, Zeljko Romic, Biserka Orehovec, Gorana Aralica, Marko Miletic, Rajko Kusec
OBJECTIVES: To investigate the clinical and prognostic significance of absolute basophil count (ABC) in patients with primary myelofibrosis (PMF). METHODS: We retrospectively investigated 58 patients with PMF treated in our institution in the period from 2006 to 2017. ABC was obtained in addition to other hematological and clinical parameters. Patients were separated into high and low ABC groups using the Receiver operating characteristic curve analysis. RESULTS: ABC was higher in PMF patients than in healthy controls (P < 0...
September 14, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/28901688/poly-glycerol-sebacate-combined-with-chondroitinase-abc-promotes-spinal-cord-repair-in-rats
#16
Qi Pan, Yan Guo, Fanyong Kong
This study was to investigate the feasibility of PGS combined with ChABC for repairing the transection of spinal cords (TSC) in rats. A thoracic 10 (T10) TSC model of rats was employed. The effects of PGS with ChABC on the morphology and histological structure of the spinal cords, Basso, Beattie, Bresnahan (BBB) scores, and the expression of GAP-43 and NF-200 were comparatively studied. The BBB scores indicated that all rats with TSC were paralyzed immediately after surgery and then recovered hind limb movement gradually, but did not fully recover until the end of week 12...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28900668/validation-of-the-baragwanath-mortality-prediction-score-for-cerebral-gunshot-wounds-the-pietermaritzburg-experience
#17
V Y Kong, G V Oosthuizen, B Sartorious, J L Bruce, G L Laing, R Weale, D L Clarke
INTRODUCTION: Cerebral gunshot wounds (GSW) are highly lethal injuries. To date, only one clinical scoring system to predict mortality in a developing world setting has been described. This is the Baragwanath mortality prediction score ("ABC": admission blood pressure, brain matter spillage and consciousness level). MATERIALS AND METHODS: We performed a retrospective review of prospectively entered data for a cohort of patients with isolated cerebral GSWs over a 5-year period (January 2010-December 2014) in our institution...
September 12, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28886676/validity-reliability-and-minimal-detectable-change-of-the-balance-evaluation-systems-test-bestest-mini-bestest-and-brief-bestest-in-patients-with-end-stage-renal-disease
#18
Cristina Jácome, Inês Flores, Filipa Martins, Conceição Castro, Charlotte C McPhee, Ellen Shepherd, Sara Demain, Daniela Figueiredo, Alda Marques
PURPOSE: This study determined the validity, test-retest reliability and minimal detectable change of the balance evaluation systems test (BESTest), mini-balance evaluation systems test (Mini-BESTest) and brief-balance evaluation systems test (Brief-BESTest) in patients with end-stage renal disease. METHODS: A cross-sectional study with 74 patients with end-stage renal disease (male 66.2%; 63.9 ± 15.1 years old) was conducted. Participants were asked to report the number of falls during the previous 12 months and to complete the activity-specific balance confidence (ABC) scale...
September 8, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28880238/implications-of-abcg2-expression-on-irinotecan-treatment-of-colorectal-cancer-patients-a-review
#19
REVIEW
Dorte Lisbet Nielsen, Jesper Andreas Palshof, Nils Brünner, Jan Stenvang, Birgitte Martine Viuff
BACKGROUND: One of the main chemotherapeutic drugs used on a routine basis in patients with metastatic colorectal cancer ((m)CRC) is the topoisomerase-1 inhibitor, irinotecan. However, its usefulness is limited by the pre-existing or inevitable development of resistance. The ATP-binding cassette (ABC) transporter ABCG2/breast cancer resistance protein (BRCP) through its function in xenobiotic clearance might play an important role in irinotecan resistance. With a goal to evaluate the clinical significance of ABCG2 measurements, we here review the current literature on ABCG2 in relation to irinotecan treatment in CRC patients...
September 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28880130/the-effects-of-semi-immersive-virtual-reality-therapy-on-standing-balance-and-upright-mobility-function-in-individuals-with-chronic-incomplete-spinal-cord-injury-a-preliminary-study
#20
Chang-Man An, Young-Hyun Park
Background Individuals with chronic incomplete spinal cord injury (iSCI) commonly face persistent balance or mobility impairments. Virtual reality (VR) therapy is a useful rehabilitation approach; however, little is known about its effects in individuals with chronic iSCI. Objective To investigate the effects of semi-immersive VR therapy on standing balance and upright mobility function in individuals with chronic iSCI. Methods Ten subjects with chronic iSCI underwent VR therapy 30 minutes a day, 3 days a week, for 6 weeks...
September 7, 2017: Journal of Spinal Cord Medicine
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