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https://www.readbyqxmd.com/read/29208449/surgical-treatment-of-thoracic-spinal-tuberculosis-a-multi-center-retrospective-study
#1
Wenjie Wu, Jingtong Lyu, Xun Liu, Fei Luo, TianYong Hou, Qiang Zhou, Zhilin Li, Yuan Chen, Li Tao Li, Yonghong Zheng, Gaoju Wang, Jianzhong Xu, Zehua Zhang
OBJECTIVE: The aim present multicenter retrospective study is to assess safety and effectiveness of different surgery strategy in thoracic tuberculosis, and to provide a reference for surgical treatment of thoracic tuberculosis. MATERIALS AND METHODS: This study reviewed 394 patients with thoracic tuberculosis who were treated in six institution between January 2000 and January 2015. There were 208 males and 186 females with average ages of 34.92±13.14 years (range 5-76 years)...
December 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29205071/impact-of-helmet-use-in-equestrian-related-traumatic-brain-injury-a-matched-pairs-analysis
#2
Georg Bier, Malte N Bongers, Ahmed Othman, Johann-Martin Hempel, Volker Vieth, Walter Heindel, Ulrike Ernemann, Matthias C Burg
PURPOSE: Traumatic brain injury is an important health concern in equestrian sports. Nevertheless, the use of safety helmets, especially in recreational riding, is reported to be rare. The purpose of this study was to perform the first matched-pairs analysis of traumatic brain injury with regard to the use of helmets. MATERIALS AND METHODS: In a multicenter retrospective database analysis 40 patients (mean age: 35 ± 17.13 years; 34 female & 6 male) were combined in 20 matched pairs based on age group, gender and trauma mechanism...
December 5, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29201841/the-combined-use-of-cardiac-output-and-intracranial-pressure-monitoring-to-maintain-optimal-cerebral-perfusion-pressure-and-minimize-complications-for-severe-traumatic-brain-injury
#3
Jin Shup So, Jung-Ho Yun
Objective: To show the effect of dual monitoring including cardiac output (CO) and intracranial pressure (ICP) monitoring for severe traumatic brain injury (TBI) patiens. We hypothesized that meticulous treatment using dual monitoring is effective to sustain maintain minimal intensive care unit (ICU) complications and maintain optimal ICP and cerebral perfusion pressure (CPP) for severe TBI patiens. Methods: We included severe TBI, below Glasgow Coma Scale (GCS) 8 and head abbreviation injury scale (AIS) >4 and performed decompressive craniectomy at trauma ICU of our hospital...
October 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29198400/osteochondritis-dissecans-of-skeletal-elements-of-the-foot-in-a-19th-century-rural-farming-community-from-the-netherlands
#4
Irene Vikatou, Menno L P Hoogland, Andrea L Waters-Rist
Osteochondritis Dissecans (OD) is a pathological condition of the subchondral bone and surrounding cartilage of synovial joints, associated with strenuous activity and/or trauma. Reports of OD in archaeological skeletal remains are few and the majority demonstrate low OD prevalence (<1%). A predominantly 19th century skeletal sample from Middenbeemster, the Netherlands, was assessed for OD. The sample included adult individuals of both sexes. There were no definitive OD lesions in non-pedal elements, yet 12...
December 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29198186/screening-in-trauma-for-opioid-misuse-prevention-stomp-study-protocol-for-the-development-of-an-opioid-risk-screening-tool-for-victims-of-injury
#5
Randall Brown, Brienna Deyo, Chelsea Riley, Andrew Quanbeck, Joseph E Glass, Rebecca Turpin, Scott Hetzel, Christopher Nicholas, Maireni Cruz, Suresh Agarwal
BACKGROUND: Opioid addiction and overdose are epidemic in the U.S. Victims of traumatic injury are at greater than average risk for opioid misuse and related complications. Potential risk screens and preventive interventions in this clinical population remain under-investigated. The current project seeks to develop and pilot the implementation of a screening tool for opioid risk at American College of Surgeons (ACS) Level I and Level II trauma centers. METHODS: The project began with an online survey, which was sent to Wisconsin trauma center medical directors and trauma coordinators for the purpose of gathering information on current substance use screening practices...
December 4, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29181183/internal-fixation-combined-with-bone-grafting-for-large-intraosseous-calcaneal-lipoma-a-case-report
#6
Yongxing Cao
Intraosseous lipoma is a rare benign bone tumor that has been reported to occur in the calcaneus and long bones. The etiology of intraosseous lipoma is unknown, although several theories have been proposed. The majority of the cases of intraosseous calcaneal lipoma reported in the literature were localized in the anterior portion of the calcaneus and were treated by curettage and bone grafting. However, for larger lipomas, no specific treatment protocol has been developed to date. We herein present a rare case involving a large intraosseous lipoma of the calcaneus in a 36-year-old man following hindfoot trauma...
November 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29177620/revisiting-traumatic-cardiac-arrest-should-cpr-be-initiated
#7
Katie L Konesky, Weidun Alan Guo
OBJECTIVES: Traumatic cardiac arrest (TCA) represents a unique problem, and poses difficult challenges in the care of trauma patients. Although the literature has suggested that attempted resuscitation from TCA in trauma is futile and consumptive of medical and human resources, studies have recently demonstrated that the outcome of TCA is comparable cardiac arrest secondary to non-traumatic events. The objective of this study was to determine the incidence, predictors, and outcomes following TCA...
November 25, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29176735/interplay-between-trauma-and-pseudomonas-entomophila-infection-in-flies-a-central-role-of-the-jnk-pathway-and-of-creba
#8
Ramy Ragheb, Alexandre Chuyen, Magali Torres, Arnaud Defaye, Denis Seyres, Laurent Kremmer, Nicolas Fernandez-Nunez, Hervé Tricoire, Pascal Rihet, Catherine Nguyen, Laurence Röder, Laurent Perrin
In mammals, both sterile wounding and infection induce inflammation and activate the innate immune system, and the combination of both challenges may lead to severe health defects, revealing the importance of the balance between the intensity and resolution of the inflammatory response for the organism's fitness. Underlying mechanisms remain however elusive. Using Drosophila, we show that, upon infection with the entomopathogenic bacterium Pseudomonas entomophila (Pe), a sterile wounding induces a reduced resistance and increased host mortality...
November 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29176329/inflammatory-processes-during-acute-respiratory-distress-syndrome-a-complex-system
#9
Lucy K Reiss, Andreas Schuppert, Stefan Uhlig
PURPOSE OF REVIEW: ARDS is a severe pulmonary disease characterized by inflammation. However, inflammation-directed therapies have yet failed to improve the outcome in ARDS patients. One of the reasons may be the underestimated complexity of inflammation. Here, we summarize recent insights into the complex interrelations between inflammatory circuits. RECENT FINDINGS: Gene expression analysis from animal models or from patients with ARDS, sepsis or trauma show an enormous number of differentially expressed genes with highly significant overlaps between the various conditions...
November 15, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29174329/initial-inferior-vena-cava-diameter-predicts-massive-transfusion-requirements-in-blunt-trauma-patients-a-retrospective-cohort-study
#10
Hiroaki Takada, Toru Hifumi, Hayato Yoshioka, Ichiro Okada, Nobuaki Kiriu, Junichi Inoue, Kohei Morimoto, Junichi Matsumoto, Yuichi Koido, Hiroshi Kato
OBJECTIVES: The inferior vena cava (IVC) diameter is associated with shock and increased mortality in trauma patients. However, there are no reports examining the association between the IVC diameter and massive transfusion (MT) requirements in trauma patients. The aim of this study was to evaluate the association between IVC diameter and MT requirements in patients with blunt trauma. METHODS: We retrospectively reviewed all patients who were consecutively hospitalized with blunt trauma (Injury Severity Score [ISS] ≥16) between from November 1, 2011 to March 30, 2016...
November 21, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29170311/14%C3%A2-prediction-of-massive-blood-transfusion-in-battlefield-trauma-development-and-validation-of-the-military-acute-severe-haemorrhage-mash-score
#11
Jackie Mclennan, Jason Smith, Kevin Mackway-Jones
BACKGROUND: The predominant cause of preventable death from trauma is bleeding. Many patients need resuscitation with massive blood transfusion (MBT). In some theatres of military operation there is limited blood product availability and walking donor panels can be required. This study aimed to produce a tool to predict the need for MBT using information available on patient arrival at the ED for patients sustaining battlefield trauma. METHODS: A retrospective database analysis was undertaken using the UK Joint Theatre Trauma Registry (JTTR) to provide derivation and validation datasets...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29166890/continuous-passive-motion-and-physical-therapy-cpm-versus-physical-therapy-pt-versus-delayed-physical-therapy-dpt-after-surgical-release-for-elbow-contractures-a-study-protocol-for-a-prospective-randomized-controlled-trial
#12
Jetske Viveen, Job N Doornberg, Izaak F Kodde, Pjotr Goossens, Koen L M Koenraadt, Bertram The, Denise Eygendaal
BACKGROUND: The elbow is prone to stiffness after trauma. To regain functional elbow motion several conservative- and surgical treatment options are available. Conservative treatment includes physical therapy, intra-articular injections with corticosteroids and a static progressive or dynamic splinting program. If conservative treatment fails, an operative release of the posttraumatic stiff elbow is often performed. The best Evidence-Based rehabilitation protocol for patients after an operative release is unknown to date and differs per surgeon, hospital and country...
November 22, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29157219/a-new-multiple-trauma-model-of-the-mouse
#13
Stefanie Fitschen-Oestern, Sebastian Lippross, Tim Klueter, Matthias Weuster, Deike Varoga, Mersedeh Tohidnezhad, Thomas Pufe, Stefan Rose-John, Hagen Andruszkow, Frank Hildebrand, Nadine Steubesand, Andreas Seekamp, Claudia Neunaber
BACKGROUND: Blunt trauma is the most frequent mechanism of injury in multiple trauma, commonly resulting from road traffic collisions or falls. Two of the most frequent injuries in patients with multiple trauma are chest trauma and extremity fracture. Several trauma mouse models combine chest trauma and head injury, but no trauma mouse model to date includes the combination of long bone fractures and chest trauma. Outcome is essentially determined by the combination of these injuries...
November 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29155254/association-of-riluzole-and-dantrolene-improves-significant-recovery-after-acute-spinal-cord-injury-in-rats
#14
Bernardo De Caro Martins, Bruno Benetti Junta Torres, Karen Maciel de Oliveira, Mario Sergio Lavor, Carla Maria Osório, Fabiola Bono Fukushima, Isabel Rodrigues Rosado, Eliane Gonçalves de Melo
BACKGROUND CONTEXT: Damage to the spinal cord can result in irreversible impairment or complete loss of motor, sensory, and autonomic functions. Riluzole and dantrolene have been shown to provide neuroprotection by reducing neuronal apoptosis after brain and spinal cord injury (SCI) in several animal models of neurological disorders. As these drugs protect the injured spinal cord through different mechanisms, we investigated the cumulative effects of riluzole and dantrolene. PURPOSE: This study aimed to investigate the neuroprotective efficacy of the combined administration of riluzole and dantrolene in experimental thoracic SCI...
November 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29149741/the-isolated-posterior-malleolar-fracture-and-syndesmotic-instability-a-case-report-and-review-of-the-literature
#15
Diederik P J Smeeing, Roderick M Houwert, Moyo C Kruyt, Falco Hietbrink
INTRODUCTION: Ankle fractures are among the most common type of fractures in the lower extremity. A posterior malleolar fracture is frequently part of a more complex ankle fracture and only in rare cases it occurs as isolated injury. Posterior malleolar fractures often occur with associated injuries, such as a Maisonneuve fracture or with bi- or trimalleolar ligamentous injuries. Knowledge about these associated injuries is essential to prevent missed diagnoses. The aim of this article is to describe the isolated posterior malleolar fracture, the possible associated injuries, the diagnostic work-up and therapeutic consequences...
November 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29145287/transforaminal-endoscopy-in-lumbar-burst-fracture-a-case-report
#16
Yuanyi Wang, Cong Ning, Liyu Yao, Xiuying Huang, Chengliang Zhao, Bin Chen, Nan Zhang
RATIONALE: Lumbar burst fractures are frequent injury resulting from high-energy trauma, and the patients suffer from pain and the neurologic dysfunction. Although minimally invasive techniques have advanced rapidly, it was the first time to apply transforaminal endoscopic combined with percutaneous pedicle screw fixation to treatment of lumbar burst fractures. PATIENT CONCERNS: A 33-year-old man underwent Magerl type A3.1 burst fracture at L2 and compression fractures at L3 due to falling from a height with severe lower back pain, sensory loss, and atony of the right leg...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29140953/contemporary-management-of-rectal-injuries-at-level-i-trauma-centers-the-results-of-an-american-association-for-the-surgery-of-trauma-multi-institutional-study
#17
Carlos V R Brown, Pedro G Teixeira, Elisa Furay, John P Sharpe, Tashinga Musonza, John Holcomb, Eric Bui, Brandon Bruns, H Andrew Hopper, Michael S Truitt, Clay C Burlew, Morgan Schellenberg, Jack Sava, John VanHorn, Brian Eastridge, Alicia M Cross, Richard Vasak, Gary Vercruysse, Eleanor E Curtis, James Haan, Raul Coimbra, Phillip Bohan, Stephen Gale, Peter G Bendix
INTRODUCTION: Rectal injuries have been historically treated with a combination of modalities including direct repair, resection, proximal diversion, presacral drainage, and distal rectal washout. We hypothesized that intraperitoneal rectal injuries may be selectively managed without diversion and the addition of distal rectal washout and pre-sacral drainage in the management of extraperitoneal injuries are not beneficial. METHODS: This is an American Association for the Surgery of Trauma multi-institutional retrospective study from 2004-2015 of all patients who sustained a traumatic rectal injury and were admitted to one of the 22 participating centers...
November 14, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29132543/intravenous-administration-of-functionalized-magnetic-iron-oxide-nanoparticles-does-not-induce-cns-injury-in-the-rat-influence-of-spinal-cord-trauma-and-cerebrolysin-treatment
#18
Preeti K Menon, Aruna Sharma, José V Lafuente, Dafin F Muresanu, Zoraida P Aguilar, Y Anderw Wang, Ranjana Patnaik, Herbert Mössler, Hari S Sharma
Influence of iron oxide magnetic nanoparticles (IOMNPs, 10nm in diameter, 0.25 or 0.50mg/mL in 100μL, i.v.) on the blood-brain barrier (BBB) permeability, edema formation, and neuronal or glial changes within 4-24h after administration was examined in normal rats and after a focal spinal cord injury (SCI). Furthermore, effect of cerebrolysin, a balanced composition of several neurotrophic factors, and active peptide fragments was also evaluated on IOMNP-induced changes in central nervous system (CNS) pathology...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/29126602/the-potential-of-blended-learning-in-education-and-training-for-advanced-civilian-and-military-trauma-care
#19
Linda Sonesson, Kenneth Boffard, Lars Lundberg, Martin Rydmark, Klas Karlgren
INTRODUCTION: In the field of advanced care of the complex trauma patient, there is an emerging need for focused education and training. However, several hospitals do not support further education and training in this field, and the challenge of releasing time for physicians and nurses is well-known. Educational strategies using blended learning, which combines traditional classroom methods with modern computer-assisted methods and media, have not yet been widely used. This study analysed the educational challenges and areas for improvement, according to senior physicians and nurses, and investigated the potential use of blended learning...
November 6, 2017: Injury
https://www.readbyqxmd.com/read/29125800/the-trauma-factor-examining-the-relationships-among-different-types-of-trauma-dissociation-and-psychopathology
#20
Adriano Schimmenti
Extensive research has reported a dose-response relationship between exposure to trauma and the severity of both dissociation and psychopathology. However, certain types of trauma may co-occur more frequently than others and specific combinations of traumatic experiences may relate differently to dissociative processes and psychiatric symptoms. In the current study, 359 adult participants completed questionnaires on traumatic experiences, dissociation, and psychopathology. A correlation network analysis showed that some types of trauma are more likely to co-occur and that especially traumatic experiences in attachment relationships during childhood were significantly associated with other trauma in life...
November 10, 2017: Journal of Trauma & Dissociation
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