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Insulin adherence type 1 diabetes

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https://www.readbyqxmd.com/read/29773934/iglarlixi-a-new-once-daily-fixed-ratio-combination-of-basal-insulin-glargine-and-lixisenatide-for-the-management-of-type-2-diabetes
#1
Debbie Hinnen, Jodi Strong
Background: Patients with type 2 diabetes require treatment intensification to maintain glycemic control. Clinician reluctance, patient injection fears, hypoglycemia, weight gain, or other objections may lead to clinical inertia, whereby therapy is not intensified and patients live with uncontrolled hyperglycemia and increased risk for complications. Initiation of injectable therapy with a glucagon-like peptide (GLP)-1 receptor agonist and/or basal insulin is a recommended option for patients with type 2 diabetes inadequately controlled on one or more oral agents...
May 2018: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29756487/evaluation-of-the-relationship-between-loneliness-and-medication-adherence-in-patients-with-diabetes-mellitus-a-cross-sectional-study
#2
Dilek Kusaslan Avci
Objective The emotional status of patients with diabetes mellitus (DM) is important in the course of treatment. The present study aimed to determine the level of loneliness among patients with DM and to evaluate the relationship between the patients' level of loneliness and medication adherence. Method This cross-sectional study used a semi-structured questionnaire and the University of California, Los Angeles Loneliness Scale to collect data from 325 patients who were diagnosed with DM. Results We found that loneliness scores were significantly elevated in individuals with a low level of education, unmarried individuals, and students...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29745337/factors-associated-with-poor-hemoglobin-a1c-control-in-patients-with-type-2-diabetes
#3
Salam Alqudah, Anan S Jarab, Eman A Alefishat, Fadia Mayyas, Maher Khdour, Sharrel Pinto
Background The limited implementation of clinical pharmacy service programs and the lack of studies identifying barriers to achieve blood glucose control have all attributed to the increased proportion of type 2 diabetes patients who have poor glycemic control in Jordan. Objective To explore factors associated with higher HbA1c in patients with type 2 diabetes in Jordan. Method Variables including socio-demographics, disease and treatment factors were collected from171 patients with type2 diabetes at an outpatient diabetes clinic in Amman...
May 10, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29741747/health-related-stigma-in-young-adults-with-type-1-diabetes-mellitus
#4
Yoo Mi Jeong, Laurie Quinn, Nahyun Kim, Pamela Martyn-Nemeth
Young adults with type 1 diabetes mellitus (T1DM) often exhibit poor treatment adherence and suboptimal glucose control. Health-related stigma may adversely influence diabetes self-management behavior. The aim of the current study was to explore health-related stigma among young adults with T1DM using qualitative descriptive methods in focus groups. Data were collected from a purposive sample of 14 young adults ages 20 to 34 with T1DM. Using content analysis, transcripts from two focus groups were analyzed, and five main themes were identified: (a) Desire to be Seen as a Person, Not a Disease; (b) Wanting to be "Normal"; (c) Feeling Ashamed Managing Diabetes in Public; (d) Struggling to Overcome Anger and Distress; and (e) Feeling Distrusted by Others to Manage Their Condition...
May 8, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29674306/diabeo-app-software-and-telemedicine-versus-usual-follow-up-in-the-treatment-of-diabetic-patients-protocol-for-the-telesage-randomized-controlled-trial
#5
Nathalie Jeandidier, Lucy Chaillous, Sylvia Franc, Pierre-Yves Benhamou, Pauline Schaepelynck, Hélène Hanaire, Bogdan Catargi, Anne Farret, Pierre Fontaine, Bruno Guerci, Yves Reznik, Alfred Penfornis, Sophie Borot, Pierre Serusclat, Yacine Kherbachi, Geneviève D'Orsay, Bruno Detournay, Pierre Simon, Guillaume Charpentier
BACKGROUND: Self-management of diabetes minimizes the risk of macrovascular and microvascular complications, but understanding and/or adherence to self-management recommendations is often suboptimal. DIABEO is a smartphone app (downloaded via the internet) used to calculate bolus insulin doses. A previous study (TELEDIAB 1) showed that the use of DIABEO was associated with a significant improvement in glycemic control in patients with poorly controlled type 1 diabetes mellitus, particularly when combined with teleconsultations with physicians...
April 19, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29666033/antidiabetics-usage-in-type-2-diabetes-mellitus-are-prescribing-guidelines-adhered-to-a-single-centre-study
#6
Viviane Khalil, Christy Sajan, Tiffany Tsai, David Ma
AIM: The primary aim of this study was to examine the prescribing patterns of antidiabetic agents (AA) in this hospital according to current prescribing contraindications (PCI). The secondary aims are to assess factors affecting the prescribing of AA and to evaluate the pharmacist impact on their prescribing. METHOD: A retrospective cross sectional study was performed to review all prescribed AA over a 3 month period. Data extracted from medical records included: patients' demographics, management and pharmacists' interventions...
April 11, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29644618/adherence-to-basal-insulin-therapy-among-people-with-type-2-diabetes-a-retrospective-cohort-study-of-costs-and-patient-outcomes
#7
Magaly Perez-Nieves, Kristina S Boye, Jacek Kiljanski, Dachung Cao, Maureen J Lage
INTRODUCTION: This research compares costs, resource utilization, and complications between adherent and nonadherent patients over the 3-year period post initiation on basal insulin therapy. METHODS: The study utilized the US-based Truven Health MarketScan® Research Databases from 2011 through 2015. Adults aged 18 years or older and identified with type 2 diabetes (T2D) who initiated therapy on basal insulin in 2012 were included. Patients were excluded if they were pregnant, filled their index basal insulin prescription via mail order, or were not continuously insured from 1 year before through 3 years following initiation of treatment with basal insulin...
April 11, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29602844/impact-of-gestational-weight-gain-and-prepregnancy-body-mass-index-on-the-prevalence-of-large-for-gestational-age-infants-in-two-cohorts-of-women-with-type-1-insulin-dependent-diabetes-a-cross-sectional-population-study
#8
Ketrell L McWhorter, Katherine Bowers, Lawrence M Dolan, Ranjan Deka, Chandra L Jackson, Jane C Khoury
OBJECTIVES: Despite improvements in treatment modalities, large-for-gestational age (LGA) prevalence has remained between 30% and 40% among infants of mothers with type 1 insulin-dependent diabetes mellitus (TIDM). Our objective was to estimate LGA prevalence and examine the association between gestational weight gain (GWG) and prepregnancy body mass index (BMI) with LGA among mothers with TIDM. DESIGN: Cross-sectional study. SETTING: Regional data in Cincinnati, Ohio, from the Diabetes in Pregnancy Program Project (PPG), a prospective cohort for the period 1978-1993; national data from Consortium on Safe Labor (CSL), a multicentre cross-sectional study for the period 2002-2008...
March 30, 2018: BMJ Open
https://www.readbyqxmd.com/read/29575241/randomized-controlled-feasibility-trial-of-supported-self-management-in-adults-with-type-2-diabetes-mellitus-and-an-intellectual-disability-ok-diabetes
#9
A House, L Bryant, Amy M Russell, A Wright-Hughes, L Graham, R Walwyn, J M Wright, C Hulme, J L O'Dwyer, G Latchford, A Stansfield, R Ajjan, A Farrin
AIMS: To undertake a feasibility randomized controlled trial of supported self-management vs treatment as usual in a population of adults with obesity, Type 2 diabetes and an intellectual disability. METHODS: We conducted an individually randomized feasibility trial. Participants were adults aged >18 years with a mild or moderate intellectual disability, living in the community with Type 2 diabetes, on any therapy other than insulin. Participants had mental capacity to consent to research and the intervention...
March 25, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29549246/an-audit-of-the-dietary-intake-of-australian-children-with-type-1-diabetes
#10
Heather R Gilbertson, Kristen Reed, Sarah Clark, Kate L Francis, Fergus J Cameron
To understand what children with type 1 diabetes in a representative tertiary hospital clinic are eating compared to their peers and explore dietary intake impact on HbA1c outcome. An open cross-sectional dietary audit of children and adolescents with diabetes aged 2-17 years attending the Royal Children's Hospital, Melbourne was conducted using an age-appropriate validated Food Frequency Questionnaire. Total energy, macronutrient intake and diet quality were calculated and compared to dietary advice provided and national intake data...
March 9, 2018: Nutrition & Diabetes
https://www.readbyqxmd.com/read/29535079/human-factors-and-data-logging-processes-with-the-use-of-advanced-technology-for-adults-with-type-1-diabetes-systematic-integrative-review
#11
REVIEW
Marion Waite, Clare Martin, Rachel Franklin, David Duce, Rachel Harrison
BACKGROUND: People with type 1 diabetes (T1D) undertake self-management to prevent short and long-term complications. Advanced technology potentially supports such activities but requires consideration of psychological and behavioral constructs and usability issues. Economic factors and health care provider capacity influence access and uptake of advanced technology. Previous reviews have focused upon clinical outcomes or were descriptive or have synthesized studies on adults with those on children and young people where human factors are different...
March 15, 2018: JMIR Human Factors
https://www.readbyqxmd.com/read/29416318/adherence-to-dietary-recommendations-in-diabetes-mellitus-disease-acceptance-as-a-potential-mediator
#12
Mariusz Jaworski, Mariusz Panczyk, Małgorzata Cedro, Alicja Kucharska
Background: Adherence by diabetic patients to dietary recommendations is important for effective therapy. Considering patients' expectations in case of diet is significant in this regard. The aim of this paper was to analyze the relationship between selected independent variables (eg, regular blood glucose testing) and patients' adherence to dietary recommendations, bearing in mind that the degree of disease acceptance might play a mediation role. Subjects and methods: A cross-sectional study was conducted in 91 patients treated for type 2 diabetes mellitus in a public medical facility...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29394488/effect-of-7-days-of-exercise-on-exogenous-carbohydrate-oxidation-and-insulin-resistance-in-children-with-obesity
#13
Lisa Chu, Katherine M Morrison, Michael C Riddell, Sandeep Raha, Brian W Timmons
PURPOSE: The capacity to match carbohydrate (CHO) oxidation with CHO availability (deemed metabolic flexibility (MetFlex)) may be important for type 2 diabetes prevention. In adults, impaired MetFlex is associated with insulin resistance (IR), which can be improved with as little as 7 days of exercise. Whether this occurs similarly in children is unknown. We hypothesized 7 consecutive days of exercise would improve MetFlex and IR in children with obesity. METHODS: Twelve children (8 boys, 4 girls) completed 2 study visits before (PRE) and 2 study visits after (POST) exercise training...
February 2, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29357987/patient-perspectives-on-nurse-led-consultations-within-a-pilot-structured-transition-program-for-young-adults-moving-from-an-academic-tertiary-setting-to-community-based-type-1-diabetes-care
#14
Sandra Zoni, Marie-Elise Verga, Michael Hauschild, Marie-Paule Aquarone-Vaucher, Teresa Gyuriga, Anne-Sylvie Ramelet, Andrew A Dwyer
PURPOSE: We aimed to evaluate patient self-management activities, patient perceptions of the therapeutic relationship and satisfaction with nurse-led consultations as part of a structured, pilot program transitioning young adults with type 1 diabetes (T1DM) to adult-oriented community-based practices. DESIGN AND METHODS: A descriptive, cross-sectional study of patients receiving nurse-led consultations. Patients provided sociodemographic/health information, glycated hemoglobin (HbA1c) measures and completed questionnaires assessing self-management (Revised Self-Care Inventory) and the therapeutic relationship (Caring Nurse-Patient Interaction - short scale)...
January 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29356607/effects-of-aerobic-and-resistance-exercise-on-metabolic-syndrome-sarcopenic-obesity-and-circulating-biomarkers-in-overweight-or-obese-survivors-of-breast-cancer-a-randomized-controlled-trial
#15
Christina M Dieli-Conwright, Kerry S Courneya, Wendy Demark-Wahnefried, Nathalie Sami, Kyuwan Lee, Thomas A Buchanan, Darcy V Spicer, Debu Tripathy, Leslie Bernstein, Joanne E Mortimer
Purpose Metabolic syndrome is associated with an increased risk of cardiovascular disease, type 2 diabetes, and breast cancer recurrence in survivors of breast cancer. This randomized controlled trial assessed the effects of a 16-week combined aerobic and resistance exercise intervention on metabolic syndrome, sarcopenic obesity, and serum biomarkers among ethnically diverse, sedentary, overweight, or obese survivors of breast cancer. Methods Eligible survivors of breast cancer (N = 100) were randomly assigned to exercise (n = 50) or usual care (n = 50)...
March 20, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29327220/patient-perceptions-and-preferences-for-a-mealtime-insulin-delivery-patch
#16
Mark Peyrot, Darlene Dreon, Vivien Zraick, Brett Cross, Meng H Tan
INTRODUCTION: A basal-bolus insulin regimen is needed to achieve glycated hemoglobin A1c (HbA1c) below 7.0% in people with type 1 (T1D) or type 2 (T2D) diabetes who have significant loss of beta-cell function. Nonadherence to therapy is common and negatively affects the ability to reach treatment goals. We examined patient assessment of a new, wearable mealtime insulin-delivery system (patch) relative to their current mealtime insulin-delivery system (syringe, pen, or pump). The patch is designed to deliver only boluses of fast-acting insulin (no basal insulin), mechanically controlled by the patient...
February 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29261476/user-experience-of-an-innovative-mobile-health-program-to-assist-in-insulin-dose-adjustment-outcomes-of-a-proof-of-concept-trial
#17
Hang Ding, Farhad Fatehi, Anthony W Russell, Mohan Karunanithi, Anish Menon, Dominique Bird, Leonard C Gray
BACKGROUND: Many patients with diabetes require insulin therapy to achieve optimal glycemic control. Initiation and titration of insulin often require an insulin dose adjustment (IDA) program, involving frequent exchange of blood glucose levels (BGLs) and insulin prescription advice between the patient and healthcare team. This process is time consuming with logistical barriers. OBJECTIVE: To develop an innovative mobile health (m-Health) mobile-based IDA program (mIDA) and evaluate the user adherence and experience through a proof-of-concept trial...
December 20, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29247092/factors-associated-with-high-levels-of-glycated-haemoglobin-in-patients-with-type-1-diabetes-a-multicentre-study-in-brazil
#18
Carine Sousa Andrade, Guilherme Sousa Ribeiro, Carlos Antonio Souza Teles Santos, Raimundo Celestino Silva Neves, Edson Duarte Moreira
OBJECTIVE: Long-term complications of type 1 diabetes mellitus (DM1) can be prevented with adequate glycaemic control. However, high levels of glycated haemoglobin (HbA1c) occur in 60%-90% of the patients with DM1. Thus, we aimed to investigate the role of sociodemographic, behavioural and clinical factors on the HbA1c levels of patients with DM1 in Brazil. DESIGN, SETTING AND PARTICIPANTS: A cross-sectional study was conducted in ambulatory patients with DM1 aged ≥18 years from 10 Brazilian cities...
December 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29215299/complex-assessment-of-metabolic-effectiveness-of-insulin-pump-therapy-in-patients-with-type-2-diabetes-beyond-hba1c-reduction
#19
Rudolf Chlup, Sarah Runzis, Javier Castaneda, Scott W Lee, Xuan Nguyen, Ohad Cohen
BACKGROUND: This prospective single-center study recruited insulin-resistant continuous subcutaneous insulin infusion (CSII) therapy-naive patients with type 2 diabetes (T2D) using insulin analog-based multiple daily injections (MDI) therapy and metformin. METHODS: A total of 23 individuals with T2D (70% male), aged a mean ± standard deviation 57.2 ± 8.03 years, with body mass index of 36.2 ± 7.02 kg/m2 , diabetes duration of 13.3 ± 4.64 years, and HbA1c of 10...
February 2018: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29183910/predictors-of-quality-of-life-and-other-patient-reported-outcomes-in-the-panorama-multinational-study-of-people-with-type-2-diabetes
#20
Clare Bradley, Eveline Eschwège, Pedro de Pablos-Velasco, Klaus G Parhofer, Dominique Simon, Hans Vandenberghe, Linda Gönder-Frederick
OBJECTIVE: PANORAMA, a nine-country cross-sectional type 2 diabetes study, investigated factors associated with quality of life (QoL), health status, and other patient-reported outcome measures (PROMs). RESEARCH DESIGN AND METHODS: Patients were randomly or consecutively selected from primary/secondary care. PROMs included the Audit of Diabetes-Dependent Quality of Life (ADDQoL) (generic QoL item and average weighted impact [AWI] scores), Diabetes Treatment Satisfaction Questionnaire (DTSQ) (patient- and physician-completed), Hypoglycemia Fear Survey-II worry subscale, and the EuroQoL-5 Dimension visual analog scale (EQ-VAS) measuring patient-reported health...
February 2018: Diabetes Care
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